>gi|114051015|ref|NP_001040400.	Bombyx mori
--------------------------MCLQG-------IRLVTFDATNTLLKFKMVPSQY
YTKMART-----YGY---RGSESDAQNKMREN--FKMMWEQHPNFG---RN-S---ILWE
EWWRQVVKLTLQD----HLP-----VGADTRSLGNTLINDFK---TSKCWDVAAG-SDTL
LQIIKKKGIA----------IGVISNSDPRLYDILQNLGLS-------------------
---------------------KYF--DFILTSYDCGFSKPDSRIFQEA-----L------
--LRCKEITKASE--SLHIGDDLEKDYIGARESGWHALLI-SNNE---------TKIPPA
-KD------------------------------------HVFANIDLLSIAISQNKLKLV
-------
>gi|50311663|ref|XP_455858.1|	Kluyveromyces lactis
------------MVPVRIPREVLKNGSLQHSR------PKIITFDAYNTLYSIKKPVMEQ
YCIVGAK-----YGI---NGNPQELTKRFPGV--FSNIRKKYPLYG---KN-SG--ITAE
QWWEYLIRDMFE-------------PIQIPNEMVEEILERFE---GDAAYTVYPD-VREF
LETMRRNHPE--------VSLGIVSNTDPIVLTLLENLDLK-------------------
---------------------KYF-DGNIYLSYDLEIKKPDPAMFNYAVSHM-LKRHNTS
GQRENLENIRPHV---WHVGDEEKTDLGGAFQAGVNGILV-DRSNSFGYFDITTPDVC--
-KKELSEDDLSLRKVLHHSEVILQESDAVTDVVQLNSRQYVLPNFKSLEALLFQQ-----
-------
>gi|21312204|ref|NP_077219.1|	Mus musculus
--------------------------MAHRLQ------MRLLTWDVKDTLIKLRRPVGEE
YASKARA-----HGV---VVEDITVEQAFRQA--YRAQSHNFPNYG---LS-RG--LTSR
QWWKDVVLHTFRLA---GVP-----DAQAMTPVADQLYEDFS---SPFTWQVLEG-AEMT
LKGCRKRGLK----------LAVVSNFDRRLEDILTGLGLR-------------------
---------------------EHF--DFVLTSEAVGCPKPDPRIFREA-----LQ-----
--RAC---VEPAV--AAHVGDSYLCDYQGSQAVGMHSFLV-AGSEPLDSAVR--DSVP--
-KE------------------------------------HILPSLSHLLPALDLLEASSP
MS-----
>gi|119607781|gb|EAW87375.1|	Homo sapiens
--------------------------MAHRLQ------IRLLTWDVKDTLLRLRHPLGEA
YATKARA-----HGL---EVEPSALEQGFRQA--YRAQSHSFPNYG---LS-HG--LTSR
QWWLDVVLQTFHLA---GVQ-----DAQAVAPIAEQLYKDFS---HPCTWQVLDG-AEDT
LRECRTRGLR----------LAVISNFDRRLEGILEGLGLR-------------------
---------------------EHF--DFVLTSEAAGWPKPDPRIFQEA-----LR-----
--LAH---MEPVV--AAHVGDNYLCDYQGPRAVGMHSFLV-VGPQALDPVVR--DSVP--
-KE------------------------------------HILPSLAHLLPALDCLEGSTP
GL-----
>gi|125977548|ref|XP_001352807.	Drosophila pseudoobscura
--------------------------MRSLNR------FRLITFDVTNTLLQFRTSPGKQ
YGEIGAL-----FGA---RCDNNELAKNFKAN--WYKMNRDYPNFG---RD-TKPPLEWQ
QWWRQLIAGTFSES---GAA----IPTEKLTNFSNHLLELYK---TSICWQPCNG-SVEL
LQHLRKELKP------NKCKLGVIANFDPRLPALLQNTKLD-------------------
---------------------QYL--DFALTSYEAQAEKPDPLIFQRA-----ME----E
SGLKH---LKPEE--CLHVGDGPTTDYLAAKELGWHAALV-HEKSYSYLMKKYGEDID--
-RD------------------------------------HVFPSLYDFHKKIS--DGAVV
-W-----
>gi|45198745|ref|NP_985774.1|	Ashbya gossypii
-----------------MSRGVLLEALARNRQ------PKVITFDAYNCLFSTRLPVAEQ
YSAVGRR-----HGV---DVAPSVLAARFPAGMLFRETSARHPDYG---KY-TG--LSVQ
GWWTLVIQRLFK-------------PAEVGEKMVAEILQRFQ---GHGAYKVFPD-ALWL
LEELRVRRPE--------VVVGVLSNSDPTMRQVLLNLGLG-------------------
---------------------SYF-TDAIYLSYDLGAKKPERRAFDAALERI-LERNPQL
LGDLGAEELRAA---CWHVGDEKSADLCGATGAGWNGILV-DRQDIYGQLGQG-SAVALG
LNQ------------------------------------FVVPDFYTVGKLFGLAYNI--
-------
>gi|114626293|ref|XP_001153430.	Pan troglodytes
--------------------------MAHRLQ------IRLLTWDVKDTLLRLRHPLGEE
YATKARA-----HGL---EVEPSALEQGFRQA--YRAQSHSFPNYG---LS-HG--LTSR
QWWLDVVLQTFHLA---GVQ-----DAQAVAPIAEQLYKDFS---HPCTWQVLDG-AEDT
LRECRTRGLR----------LAVISNFDRRLEGILGGLGLR-------------------
---------------------EHF--DFVLTSEAAGWPKPDPRIFQEA-----LR-----
--LAH---MEPVV--AAHVGDNYLCDYQGPRAVGMHSFLV-VGPQALDPVVR--DSVP--
-KE------------------------------------HILPSLAHLLPALDCLEGSTP
GL-----
>gi|110760582|ref|XP_001122672.	Apis mellifera
--------------------------MIKFVR------PRLITFDVTDTLL--MTNLEKH
YAEIGSQ-----HGL---SIDPHKLARSFKNN--FRKLSLEHPVYG---KH-TG--IGWK
NWWRQIVHNIFKEQ---HNY----ISDATLDKVANSLIKCYG---TSLCWHKYPG-TIEL
LEYLREKDLI----------LGVISNFDERLEAVLKDTRIR-------------------
---------------------FYF--SFVLTSYDFGIEKPDTLIFNEA-----LR----L
TKERHNINIIPQQ--AIHIGDSISNDYIGAKNANWNAILVQHNNDVIDE-----KKVP--
-TK------------------------------------DVFRNLQDLKLHLSTLLDKDI
-------
>gi|109110520|ref|XP_001101765.	Macaca mulatta
--------------------------MAHRLQ------IRLLTWDVKDTLLKLRHPLGEE
YATKARA-----HGL---EVEPSALEQGFRQA--YRVQSHSFPNYG---LS-HG--LTSR
QWWLDVVLQTFHLA---GVQ-----DAQAVAPIAEQLYEDFS---RPCTWQVLDG-AEDT
LRECRTRGLR----------LAVISNFDRRLEGILGALGLR-------------------
---------------------EHF--EFVLTSEAAGWPKPDPRIFQEA-----LR-----
--LAH---TEPVV--TAHVGDNYLCDYQGPRAVGMHSFLV-VDPQALDPVVR--DSVP--
-KE------------------------------------HILPSLAHLLPALDCLEGSTP
GL-----
>gi|109474992|ref|XP_001068126.	Rattus norvegicus
--------------------------MAHRLQ------MRLLTWDVKDTLIKVRRPVGEE
YASKARA-----HGV---LVEATAVEQAFRQA--FRAQSHSFPNYG---LS-LG--LTSR
QWWMDVVLHTFRLA---GVP-----DAQAMAPVADQLYEDFS---SPFAWRVLEG-AETT
LKGCRKRGMK----------LAVVSNFDRRLEDILTGLGLR-------------------
---------------------EHF--DFVLTSEAVGCPKPDPRIFREA-----LQ-----
--LAC---VEPSA--AAHVGDSYRCDYQGARAVGMHSFLV-VGAEPLDSSVR--DAVP--
-KE------------------------------------HILPSLSHLLPALDLLEASSP
VS-----
>gi|50757516|ref|XP_415547.1|	Gallus gallus
-----------------------------MLR------LRLLTWDVKDTLLRLRRPVGLI
YAAEAQA-----HGV---QVQPEALSQSFQAA--YRAQSRRFPNYG---RA-EG--LSSR
QWWVDVVKETFRLT---GVH-----EDTVLTLIAENLYRDYC---SARNWELLPE-ASET
LSWCHQHGLR----------MGVVSNFDNRLESILVQCNLR-------------------
---------------------HHF--HFVLTSEAVGVAKPDPKIFKAA-----LR-----
--LGG---VLPEQ--AAHIGDDYSKDYRAAREVGMHSFLL-HTPGQSTQ-----PEVP--
-PG------------------------------------HILPTLSHLLAVIE--KG---
-------
>gi|73971982|ref|XP_538805.2|	Canis familiaris
--------------------------MGRWLP------IRLLTWDVKDTLLRLRHPVGEE
YAAKARA-----HGL---EVEAATLGQAFRQA--YRTQSHSFPNYG---LS-QG--LTSR
RWWLDVVLQTFYLA---GVR-----DAQAVAPIADQLYEDFS---KPCTWQVLEG-AAAT
LRGCRKRGLR----------LAVVSNFDRRLEDILTGLGLR-------------------
---------------------EHF--DFVLTSEAAGWPKPDPRIFHEA-----LR-----
--LAQ---VEPAG--AAHIGDSYLCDYKGAQGVGMHSFLV-FGPEPLDSAVK--CSVP--
-QE------------------------------------HLLPSLSHLLPALDRLEGSAL
EL-----
>gi|91078274|ref|XP_971567.1|	Tribolium castaneum
-------------------------MNLSR--------FRLITFDVTDTLLKFRSAPGKQ
YGEVGAM-----YGV---LVDSNSLSANFKSH--WHKMNAEHPNFG---KN--G--LGWQ
SWWKQIVVGTFKDS---KLD----LDDRKLDSIASHLIELYE---TSMCWQPSYG-ALGL
LSYLRHRGVP----------MGVISNFDPRLDSTLVNTKLR-------------------
---------------------HYF--KFVTASYEVGVAKPSQGIFEKA-----ME----M
SGISD---IKPEE--CLHVGNTVLLDYVGARKSGWSAALI-HDKDLKQVKEKY-PFVN--
-GN------------------------------------YVFSSLYELHRYF--LENSDV
KLSAQSF
>gi|6323778|ref|NP_013849.1|	Saccharomyces cerevisiae
-------------MTYPKRIPINAWSEVHRVAR-----PLIITFDAYNTLYATKLPVMEQ
YCIVGRK-----YGI---KANPSTLTNNFPHV--FKKLKEDYPQYG---KY-SG--IKPE
QWWSILIRNVFA-------------PNEIPDEMINEILMRFE---GFDSYFVYPD-LIKF
LKDLKSRHPD--------VILGIVSNTDPIFYKLLKNIGLF-------------------
---------------------ETF-SGHIYLSYELNLAKPDRAIFQYALDDIISK----Q
PHLLEKYTREEILQHCFHIGDELKNDLEGAEAAGWTGILL-DRNDKYGFLS---NSIS--
-KPMRDEYKLSIDKIDNNSINTWEANTKQTDTLQLSERKYVVSNLEVLEELFP-------
-------
>gi|150864086|ref|XP_001382782.	Pichia stipitis
MSTEVPRGQFLSNPFEIDNIQVIRETKDHFPK------PSLISFDVFGTLYEPSPAISHQ
YHKIASE----EFGI---IKPVAEIEKEFPVL--FKELEELYPNYG---RF-NDEIQGSD
HWWSELIVRLYNIE---SYK-----TNKHSAALCNRLLNHFT---GPSAYKLYDD-VIPT
LTKLKNNGIN----------MVISTNSDGRVRDIIHNLGLA-------------------
---------------------QFFPNDNFYLSYDIGAVKPSRQFFDSVSSQFYMNNYHKR
LLRKN---QGAFLENCWHVGDSHSKDFLGAIRSGWNGVLV-DRDQTSEFFSTRTKKPE--
-KE----------EYAGCGLSGMPGKNKPTDMLMLANNRVVLTRLEQLLEMFNIE-----
-------
>gi|126297578|ref|XP_001364074.	Monodelphis domestica
--------------------------MAPRLQ--------LLTWDVKDTLLRLRHPVGKG
YAAEAQA-----HGL---KVEAAALESAFHQA--YKVQNQKFPNYG---LS-QG--LTSQ
QWWLDVVLQTFHLA---GVQ-----NSNILDSIANKLYKDFS---SAKTWQLLEG-AEST
LRQCRERGLR----------LGVVSNFDRRLEDILAHYGLL-------------------
---------------------EHF--DFILTSEAAGRAKPDPQIFRQA-----LQ-----
--LAD---VEPTQ--AAHIGDHYLNDYQAPREVGMYSFLL-MGTKPQDPFP---GTIP--
-KE------------------------------------HILPSLPHLLVALNHLEGPDP
KQ-----
>gi|121710808|ref|XP_001273020.	Aspergillus clavatus
-------------------------MASRRPR------TLLLTLDAFDTIFHPRQPVPEQ
YAAAADA-----FGLPRSTITPERLAAAFKST--FKAQSKAYPNYGREYVL-RGQYGGPR
QWWEEVIRGSFSRA-MTGDSEQFGVNNEIPPALVTYLVERFA---SSEGYALFDD-VEPF
LAAVREIKSRKRGSVFDRVLLGVISNSDDRVPAVLKSLGLRVGHVRADQGVESRRLPGFE
TDGAVGSPSRSKDGDEQVRQVDDV--DLVITSYEAGEEKPSRVIFDVA-----RR---QA
QRLAHGADDADSDWVCMHVGDDVDKDYHAALSVGWDGYYI-PRGDTA-------HDTH--
-GV------------------------------------KTIHSLLDLIPTIETYR----
-------
>gi|72081102|ref|XP_795618.1|	Strongylocentrotus purpuratus
-----------------------------MLR------YRLLTFDVNNTLMRVRNSVGDQ
YRKVAKQ-----FGV---NIKASDVNREFRIA--YKDQLCRHPNFG---VT-TS--QTTE
QWWGEVVHRTFHAA---GCD----CDKETLDNVSSKLFNDFK---TSQTWETYAE-VKEM
LIFLNRNGIA----------LGVLSNNDERLMSVMKAVDIA-------------------
---------------------EHF--AFILPSALAKCEKPDAEFFNMA-----LE-----
--RLN---IEPGL--CAHIGDNVKLDYHAARAVGMDAYLV-DREGTLIE-KH--PEVN--
-PV------------------------------------HVLSDISDLEPLIFMQ-----
-------
>gi|50291919|ref|XP_448392.1|	Candida glabrata
-------------MVFPKKIPIQNWNSKISLRT-----PKLITFDAYNTLYATVLPVMEQ
YSNVASI-----YGV---KVDPQELSANFPSV--YSKLKLEHPNYG---KN-TG--ISAK
QWWQIMITEVFK-------------PIKLSDDVVEAILDRFG---SCEAFFVYPD-LIAL
LKGIRQKYPD--------VIFGVISNADPYAGDVIKSFGLD-------------------
---------------------KYF-DGNIYLSYDVGFSKPDQKIYEYALDDI-LNRFPDL
IKNCS---KEEFKQFCWHIGDEKINDMEGPAKTGLVGILI-DRVNKYGYFDGSFADIK--
-HD------LDMHKIDNNSLESWEIGIKQTDTFQVSDREYVISNLRTLATILDVQVNE--
-------
>gi|62460484|ref|NP_001014896.1	Bos taurus
--------------------------MAHRLQ------LRLLTWDVKDTLLRLRHPVGVE
YATKARA-----HGL---EVEATALGQAFKQA--YKAQSQSFPNYG---LG-HG--LTSH
QWWLDLVQQTFHQA---GVR-----DAQAVAPIAEQLYKDFS---SPSTWQVLEG-AEAT
LRGCRKRGLK----------LAVVSNFDRRLEDILEGVGLR-------------------
---------------------EHF--DFVLTSEAAGWPKPDPRIFHEA-----LH-----
--LAQ---VEPAV--GAHIGDSYQRDYKGARAVGMHSFLV-AGPEPLDPAVK--DSVP--
-QE------------------------------------HFLPSLSHLLPALDYLEGSSA
RL-----
>gi|21483246|gb|AAM52598.1|	Drosophila melanogaster
-------STRVESQEFSSGISEISGKMRSLSR------FRLITFDVTNTLLQFRTTPGKQ
YGEIGAL-----FGA---RCDNNELAKNFKAN--WYKMNRDYPNFG---RD-TNPQMEWQ
QWWRKLIAGTFAES---GAA----IPDEKLHNFSNHLIELYK---TSICWQPCNG-SVEL
LQQLRKELKP------EKCKLGVIANFDPRLPTLLQNTKLD-------------------
---------------------QYL--DFAINSYEVQAEKPDPQIFQKA-----ME----K
SGLKN---LKPEE--CLHIGDGPTTDYLAAKELGWHSALV-HEKSYAYLVKKYGEDID--
-RD------------------------------------HVFPSLYDFHKKIS--DGAVV
-W-----
>gi|118781035|ref|XP_311235.3|	Anopheles gambiae
--------------------------SFHSPVRNNLARFRLITFDVTDTLLEYAVRPERH
YAHVINAVLEPRLGL---TLREDQIGPAFGRC--FRAMKQQYPNFGAERRRPTGSEEGWR
WWWRTLVERVVVDAAATGTDRHQAIPAPLLRAIAEQLIDDYTYDGRRVCWRQRPG-VDEL
LAKLRQPAAP-------TRTLGIVSNFDPRLEIILRNNGITPG-----------------
-------------------PPGVV--DFVVTSYEARVEKPSAAIFEAA-----LRRANQL
RRAPAGQEIRPDE--ALHIGNLCREDYGGARSAGWCALLL-L------------ATIP--
-SG------------------------------------HVFTGLPELQRRLE--QAEPL
EW-----
>gi|149633957|ref|XP_001507131.	Ornithorhynchus anatinus
-----MIVEAVTAVLETLECLFSAIGHGSRHPHLMASTLRLLTWDVKDTLLRLRRPVGEE
YAIQARA-----HGL---QLEPAALSQAFHQA--YKAQSQDYPNYG---LN-RG--LSSR
QWWTDVVRRTFLLA---GVS-----DAAATDPIADRLYRDFC---SAGNWEVVAG-AAWT
LQRCRERGLR----------LAVISNFDRRLEEILAQCGLR-------------------
---------------------QHF--EFVLTSEAAGWAKPDLRIFQEA-----LR-----
--RAH---VSPTQ--AAHIGDHLLNDYQAARRAGMHSFLV-KGSEPPSPGT---GAVP--
-SD------------------------------------HILPTLPHLLTALDHLESSNL
SH-----
>gi|124481649|gb|AAI33115.1|	Danio rerio
----------------------------MRVP------VRWVLWDVKDTLLKVRRSVGEQ
YCREAQQ-----AGL---QLSPAQVETAFRQA--YKQKSQLLPNYG---RA-QG--MDSQ
VWWTGLVRDTFGQC---GVH-----DPALLDKLANNLYHNFC---GPENWEVFSD-SNST
LKSCTALGLK--------------------------------------------------
-------------------------------QEDARVAKPDPAIFSQA-----LE-----
--RCG---VPASS--VVHVGDHYVKDYLTSRSLGIRGYLL-NRKDGQTH-----LDIP--
-PE------------------------------------HILQSLDELPARLQHNTD---
-------
>gi|63100917|gb|AAH95713.1|	Danio rerio
----------------------------MRVP------VRWVLWDVKDTLLKVRRSVGEQ
YCREAQQ-----AGL---QLSPAQVETAFRLA--YKQKSQLLPNYG---RA-QG--MDSQ
VWWTGLVRDTFGQC---GVH-----DPALLDKLANNLYHNFC---GPENWEVFSD-SNST
LKSCTALGLK----------QGVVSNFDRRLEGILRGCGLL-------------------
---------------------THF--SFIVTSEDARVAKPDPAIFSQA-----LE-----
--RCG---VPASS--VVHVGDHYVKDYLTSRSLGIRGYLL-NRKDGQKTH----LDIP--
-PE------------------------------------HILQSLDELPARLQHDTD---
-------
