>gi|126342737|ref|XP_001362233.	Monodelphis domestica
------------------------------------------------------------
------MASSVGNVADSTE-----------------------------------------
------------------------------------------------------------
-------PTKCMFSFQGLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
SPYEHPTDLKVAEG-RLRVRYVSSYFGNHPTSHLMQ--SIPGMHNSDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPNTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADS-NSAL
SMPVIPMNTIAEAVIEMINRGQIQITI-NGFNISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKNRQ-EY
EDIAVKLGTDLEYLKKV-RGKVWKQRISSPLFNTKQYTMELERLYLQMWDHYAAGNKPDH
--MI--KPVEATESA----
>gi|114646136|ref|XP_522486.2|	Pan troglodytes
------------------------------------------------------------
---------------MANI-----------------------------------------
------------------------------------------------------------
-------NLKEITLIVGVVT-ACYWNSLFCGFVFDDVSAILDNKDLHPSTPLK-TLFQND
FWGTPMSEERSHKSYRPLTVLTFRLNYLLSE-LKPMSYHLLNMIFHAVVSVIFLKVC-KL
FLDNKS--------------SVIASLLFAVHPIHTEAVTGVVGRAELLSSIFFLAAFLSY
TRS-------KGPDNSIIWTPIALTVFLVAVA-TLCKEQGITVVGICCVYEVFIAQGYTL
PL-------------LCTT--AGQFLRGKGSIP----------FSMLQTLVKLIVL----
----MFSTLLLVVIRVQVIQSQLPVFTRFDNPAAVSPT-PT--RQLTFNYLLPVNAWLLL
NPSELCCDWTMGTIPLIESLLDIRNLATFTFFCFLG------------------------
------------------------------------------------------------
------------------------TLGVFSI-------RYSGDSSK--------------
-------------------------------------TVLMALCLMALPFIPA-----SN
LFFPVGFVVAERVLYVPSMGFCILVAHGWQKI-----STKS-------VFKKLSWICLSM
VILTHSLKTFHRNWDWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQA
THVQPDDIGAHMNVGRTYKNLNRTKEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYI
NLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALE-
----L-----DRNN-ADLWYNLAIVHIELKEPNEALKNFNRALELNP----------KHK
LALFNSAIVMQESG-EVKLRPEARK-------RLLS--YINEEPLDANGYFNLG-MLAMD
DK----------------------KDNEAEIWMKKAIKLQADF-------RSALFNLA--
---------------LLY-----SQTAKELKALPILEELLRYYPDHIKGLILKGD--ILM
NQKK-----DILGAKKCFERILEMDPSNVQGKHNL----------C--------------
--------------VVYFEEKDLLKAE---------------------------------
-----RCLLETLALAPHEEYIQRHLNIVRDKISSSSFIEP--------------------
----------IFPTSKISSVEGKKIPTESVK-EIRGES------------RQTQIVKT--
------------------------------SDNKSQSKSNKQLGKNGDEETPHKTTK-DI
KEIEKKRVAALKRLEEI-E-----------------------------------------
------RILNGE-------
>gi|66793439|ref|NP_001019747.1	Xenopus tropicalis
------------------------------------------------------------
------MAASVGSVADST------------------------------------------
------------------------------------------------------------
----------------GLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVVDAEECYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKASDG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFVDLSQIPCNGKAADRIHQDGVHILINMNGYTKGARNELFALKAA
PIQAMWLGYPGTSGASFMDYIISDIETSPVDVAEQYSEKLAYMPNTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLESLPDVKIVKMKGPDSGDNVDN-NSAL
NMPVIPMSSIAEAVIEMINRGQIQITI-NGFNISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAVVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQSRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GDTLASRVAASQLTCLGCPELIAKGRQ-DY
EDTAVKLGTDLEYLKKI-RSKVWKQRISSPLFNTKQYTIDLERLYLQMWEHYSAGNKTDH
--LI--KTVESTESA----
>gi|109096064|ref|XP_001101625.	Macaca mulatta
MCPSPAPFGGEGWGRGRGGEHSPAPQVGPRGALLRNSRAAARREPRSTCTRGGPGAEGAG
LWGETARVPGLGGGGESERACAVGRRRWRWPGEAGGCCLFAAGPTRRRRRRSVRGALAAG
PAAAAPLPRAPLRAAAARRRGPGRGGCQTPGRGQGSSGGGGAMVLTTSARGGGGDRAPSR
RQGCGLAPAGAAALLAGASC-LCYGRSLQGEFVHDDVWAIVNNPDVRPGAPLRWSIFTND
FWGKGMAENTSHKSYRPLCVLTFKLNIFLTG-MNPFYFHAVNVILHCLVTLVLMYTCDKT
VFKNRGL-------------AFVTALLFAVHPIHTEAVAGIVGRADVLACLLFLLAFLSY
NRSLDQGCVGESFPSTVSPFFLLFSLFLGTCA-MLVKETGITVFGVCLVYDLFSLSNKED
KS-------------SNGALCPCSPQQPGSPQP----------SSLPGHPHRENGKQQRF
PHKGAWGGCH---------SPLPPEPKSSGFPVSPRAV-WSMMRFLTYSYLLAFNVWLLL
APVTLCYDWQVGSIPLVETIWDMRNLATILLAVVMA------------------------
------------------------------------------------------------
------------------------LLSLHCLAAFKRLEHK--------------------
-------------------------------------EVLVGLLFLVFPFIPA-----SN
LFFRVGFVVAERVLYMPSMGYCILFVHGLSKL-----CTWL-----NRCGATTLIVSTVL
LLLLFSWKTVKQNEIWLSRESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTA
LKLYPRHASALNNLGTLIR---DTAEAKMYYQKA--------------LQLHPQHNRALF
NLGN-LLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQAGIKN
CPDS-----------SDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSP----------SHH
VAMVNLGRLYRSLG----ENSMAEE-------WYKR--ALQVAHKAEILSP-LG-ALYYN
TG----------------------RYEEALQIYQEAAALQPSQ-------RELRLALA--
---QVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENH--------------
-----------DKALDVIEKALQLKPKDPKVISELF-------FTKGNQLREQNLLDKAF
ESYRVAVQLNPDQAQAWMNMGGIQHIK-------------------------------GK
YVSARAYYERALQLVPDSKL-------LKENLAKLDRLEK--------------------
------------------------------------------------------------
----------------------------------------------------------RL
QEVREKDQT---------------------------------------------------
-------------------
>gi|149042178|gb|EDL95885.1|	Rattus norvegicus
------------------------------------------------------------
------MASSVGNVADSTE-----------------------------------------
------------------------------------------------------------
-------PTKRMLSFQGLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VAEQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKLSDG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADTTNTAL
NMPVIPMNTIAEAVIEMINRGQIQITI-NGFSISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKSRQ-EY
EDIAVKLGTDLEYLKKI-RGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDH
--MI--KPVEVTESA----
>gi|74007678|ref|XP_858808.1|	Canis familiaris
------------------------------------------------------------
------MASSVGNVADSTE-----------------------------------------
------------------------------------------------------------
-------PTKRMLSFQGLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFH----------------TLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AKPPYATALHMMRNMACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKLSDG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNGDSSNTAL
NMPVIPMNTIAEAVIEMINRGQIQITI-NGFSISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKNRQ-DY
EDIAVKLGTDLEYLKKI-RGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDH
--MI--KPVEVTESA----
>gi|157013713|gb|EAA14710.5|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------RAILGNPDVLGTGSWS-QMLHND
FWGTPLVDSGSHGSYRPLCVASFKLNYLLDG-FKPFGYHLVNVLLHSLATGLVVKLA-RH
LLPAGRSG------------VAIAGLLFAAHPIHTEAVAGVVGRADLTGCIFYLLALLAY
IRH----VRWRQWGDRRQWLALAATVLLAAAA-LLCKETAVTALVVC-------------
---------------AIYDIIKGYAGSRDKHRA------------------RSLGI----
----IALSLAFIVHCRLTLPRPATLFSTADNPTARSGSLWT--RFLTFTYLPVVNFKLLL
LPDVLSFDWGMDAIPRLGTVCDRKVALAALFYLALGWALWSSCRALVNRQQSPVRPSGSK
TTPNASSFNRKLANKLNLARLLRTTTTNNNDSASINYNQSFQGAVVGKKFACHWPLGTVG
DGASKEKPFPFTTLLTAPADMCSPSLSSSSYASSSSSSSS-------------------S
STSSSCASSVRGDSADGSTDEPCLPDEGNSLHNSPAAALVMSVALLALPFLPA-----SN
LLFYVGFVVAERILYLPSVGYCLLVGLAGRGG-----RVGRSTKPFGPRRRQLVLVCVGL
LLIAYSAKTVRRNRDWADEESLFRSAVAVNP--PKALGNLGSVLSAQGRYQEAKEALKAA
LNHRPNMADVHYNLGI--------------------------------------------
-----LLQNQQDYNEAVESFRKAIRFRPSLALAYLNLGTSLIALGRCQEAASVLREGTKL
DGAGLRDRAAHENARISALLQLGNLYADQGKLQRALAIYREA---------------LHT
LPERYP-----PQGIYHRLGDIFARLNQWSEAERFQRAALEAQPDHIAAHLSYGTMLARN
SS----------------------RTSEAEQWFRRALRLAPND-------ASVHHHYA--
---------------EFL-----SSQRRTEEAFQYRVKAAELAPEDY---ALVMAAASSL
RLLDRKL-----EAERWYRQAVKLRPQEARAHTNL-------------------------
-----------GAILHLL--GRTQEAA---------------------------------
-----NSYREALRLQPDDLTTL-------SNLAKL-------------------------
------------------------------------------------------------
-----------------GVPAIS-------------------------------------
------------------------------------------------------------
-------------------
>gi|147905472|ref|NP_001087168.	Xenopus laevis
------------------------------------------------------------
---------MIAELLSSAL-----------------------------------------
------------------------------------------------------------
----------------GL---LLYLNTLGADFCYDDSRAIKTNQDLLPETPWN-HIFFND
FWGTLLTHSGSHKSYRPLCTLSFRLNYLFGG-LDPWNYHLVNVLLHSAVTGLFTNLC-KA
LFGSGCW-------------TLIAGLLFASHPIHTEAVSGIVGRADVGSGLFFLLSLLCY
MKH-----CSTRGYSLSSWCWILCAGFWAACS-MLWKEQGVTVLAVSAVYDVFVFHKLKM
NQ-------------IISV----VFKEKNVSF-----------FFSVGLLF-AWGV----
----ILLGARFY-----WMGNTPPSFSNSDNPAADCEVLLT--RTLTFFYLPTKNLWLLF
CPDTLSFDWSMDAVPLIKTITDWRNIHTVAFYILLI------------------------
------------------------------------------------------------
------------------------LLAYSSL--KGSAIKRDCNGKVFMNGKQNTNGHSCQ
SDLEHKNAEQNPVIASKLENGVKHHNSHEMQLPSTENIVVLALSLLIVPFVPA-----SN
LFFYVGFVIAERVLYIPSMGFCLLVTVGARALYIKAQKNIL---------KNLLFYATAA
LIVFYGLKTVVRNGDWKNEEMLYRSGIKVNP--AKAWGNLGNVLKSQSKIDEAENAYRNA
LYYRSNMADMLYNLGL--------------------------------------------
-----LLQENSKFSEALHYYKLAIGSRPTLASGYLNTGIILMNQGRTEEARRTFLKCSEI
PDENLKDPNAHKSSVTSCLYNLGKLYHEQGQYEDALIVYKEAI--------------QKM
PRQFSPQSLYNMMG----EAYMRLNVVSEAEHWYTE--SLKSKPDHIPAHLTYGKLLTL-
TG----------------------RKNEAERYFLKAIQLDPNK-------GNCYMHY---
-------------GQFLL------EEGRILEAAEMAKKAAELDSSEF-------DVVFNA
AHMLRQASLN-EEAEKFYKLAAGLRQNYPAALMNL-------------------------
------------GAILHLN-GKLEEAE---------------------------------
-----YNYLRALQLKPDDAI-------TQSNLRKLWNI----------------------
--------------MEKQGLKNSKT-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------
>gi|156549360|ref|XP_001601753.	Nasonia vitripennis
------------------------------------------------------------
-----MGVPARGALAAVVA-----------------------------------------
------------------------------------------------------------
-----------------ATAFACYLNSLGCGFVFDDISAIKDNRDLRPHTPLK-NVFFND
FWGTPMHKEQSHKSYRPLCVLTFRWNYMIHQ-LDPMGYHLLNVILHVGVCLLYFRTC-LM
FLPDVA--------------SFVSALLFAVHPIHTEAVTGVVGRAETLSSLFYLAALITY
TKC-------CRSKRSTGWRSLIMSMFFVFIA-MLCKEQGITATAVCVLYEIFVVQRVTL
DI-------------VLAV--KSAFDGKKISPT----------WSSEGTK-RLTAV----
----TLVTFSLLILRLHVMGSKLPVFTRFDNPASVAST-PT--RQLTYNYLAAVNLRLLF
LPIDLCCDWTMGTIPLIETLLDVRNVATLAAHSTVI------------------------
------------------------------------------------------------
------------------------GLLVTAV---LTRSRQ---TSI--------------
-------------------------------------IIIMSLAMMILPFLPA-----SN
LFFPVGFVVAERVLYAPSMGFCMLVGYGWHIL-----CEKS---------KKISVILLLS
LLLAHATKTYVRNYDWLDEYQIFMSGLKVNDRNAKLFNNVGHALESQGRFKEALNFFNMA
VQVQGDDIGAHINVGRTYNHLKMFKEAEDAYLKAKSLLPKAKPGESYQARIAPNHLNVFV
NLANLIAKNATRLEEADLLYRQAISMRADYTLAYINRGDVLIKLNRTKEAQEVYERAL--
----F-----YDSNNPDIYYNLGVVFLEQGKASQALAYLDKALEFDP----------EHE
QALLNSAILLQELG-RAELRKVARE-------RLLK--LLRKDSNNERVHFNLG-MLAMD
DH----------------------DSESAERWFRNAVALKEDF-------RSALFNLA--
---------------LLL-----ADEQRPLEAAPFLNQLVRFHPDHVKGLILLGD--IYI
NNIK-----DLDAAENCYRRILQLDPTNIQGLHNL----------C--------------
--------------VVMVERGKLGLAA---------------------------------
-----QCLERAAALAPQQDYVHRHLAIVRARISRLPKEELAAAGVSEEDVERFDES-LWM
EQPDEEQQPQSQPLHQQQTLSGAGDSGAAVDDPTSEQF------------LGKPDNSVFL
NHAVVHNHLGSKPQQKQGS-----------GDTVNARRAPVNIKGPSKHQPSAQQQQ---
--PPPQQHHPDSVVDGLSSMLKQQPSATSGVFDRTISADATAELELAQKRAASARSKLEQ
QQMLIANRSQAAAITRSKV
>gi|118089398|ref|XP_001232519.	Gallus gallus
------------------------------------------------------------
------MATSVGNVADST------------------------------------------
------------------------------------------------------------
----------------GLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEECYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHSFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKASEG-RLRIGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFVDLSQIPCNGKAADRIHQDGIHILINMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDKETSPVEVAEQYSEKLAYMPNTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDSGDSADS-NAAL
SMPVIPMNTIAEAVIEMINRGQIQITI-NGFNISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAVVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNLGLSQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKSRQ-EY
EDIAVKLGTDLEYLKKI-RGKVWKQRISSPLFNTKQYTMDLERLYLQMWDHYAAGNKPDH
--MI--KPVEASESA----
>gi|157112300|ref|XP_001657484.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MGSH
HIGIPRE---------------------------------------------------AT
LSRVLP--------------KF--------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------WS-------QGL----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------AFMILPFLPA-----SN
LFFPVGFVIAERVLYMPSMGFCILVAYGFQLL-----SERW--------NRKMTWCCLGF
LLLSHSVKTYNRNADWESEYTIFMSGLKVNQRNAKLFNNVGHALESEGKFEEALQFFHKA
VSVQQDDVGAHINVGRTYNHLKMFKEAEQAYLKAKSLLPKAKPGESYQARIAPNHLNVFL
NLANLISKNATRLEEADLLYRQAISMRSDYTQAYINRGDILIKLNRTKEAQEVYERAL--
----L-----YDSTNPDIYYNLGVVFLEQGKASQALAYLDKALEFDP----------EHE
QALLNSAILLQELG-RPELRKIARE-------RLLK--LLAKDESNERVHFNLG-MLAMD
DR----------------------NTDEAENWFRRAVHLKQDF-------RSALFNLA--
---------------LLL-----ADDHRPLEAAPFLNQLVKYHPDHIKGLILLGD--IYI
NNIK-----DLDAAENCYKRILQLDPVNIQGLHNL----------C--------------
--------------VVYVERGKLAQAQ---------------------------------
-----ACLSHAHQLAPGEDYILRHLQIVQTRIQRLRGTPDPSREKDIAFAEYDPRE----
FGGSPLTDVDLQQLINSKSVNSNDNNEEDVQ-QGEESSSSSSSSSGEASSNNDNLNNLKT
SLPHADGADGATKVSDGSSPDSSDPIFIDSEDPISATASAGDPLVANESHQQQEHRQPRI
SETSSSSGSGSSSSSSSPQTHQNHHQQHQHQHQRRRRSNSHQRHHHHQHREHADGASDRL
GGKDLDDPSSGMS------
>gi|149758509|ref|XP_001493422.	Equus caballus
------------------------------------------------------------
------MASSVGNVADSTE-----------------------------------------
------------------------------------------------------------
-------PTKRMLSFQGLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKLSDG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTAL
NMPVIPMNTIAEAVIEMINRGQIQITI-NGFSISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKNRQ-EY
EDIAVKLGTDLEYLKKI-RGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDH
--MI--KPVEVTESA----
>gi|32307150|ref|NP_858059.1|	Homo sapiens
------------------------------------------------------------
------MASSVGNVADST------------------------------------------
------------------------------------------------------------
----------------GLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKLSDG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTAL
NMPVIPMNTIAEAVIEMINRGQIQITI-NGFSISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKNRQ-EY
EDIAVKLGTDLEYLKKV-RGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDH
--MI--KPVEVTESA----
>gi|47222947|emb|CAF99103.1|	Tetraodon nigroviridis
------------------------------------------------------------
------MATSVGNVADST------------------------------------------
------------------------------------------------------------
----------------GLAE-LAHREYQSGDFEAAERHCMQLWRQEPDNTA---MLATRD
DF---------------FYTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AKPAAATSLTKSKNMACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-GYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGNVSEAEECYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAIQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVTI
VADQL-----DKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINA-------LHK
PPYEHPKDLKASGG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPEKFEVFCY-ALSPD
DSTNFRVKVVAEAHHFVDLSQISCNGKAADRIHQDGVHILVNMNGYTKGARNELFALRPA
PVQAMWLGYPGTSGAPFMDYIISDKETSPIEVAEQYSEKLAYMPHTF----FIGDHANMF
PHLKKKAVIDFKSNGHIFDNRIVLNGIDLKAFLDSLPDVKVIKMKCDNNQEPSADTNGAL
SMPVIPMNTAAEAIINMINQGQIQVTI-NGFTVSNGLATT----------------QITN
KAATGEEVLRTVVVTTRSQYGLPEDAIVYCNFNQLYKIDPPTLQMWANILTRVPNSVLWL
LRFPAVGEPNIQQYAQKVGLPASRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVATSQLSCLGCPELIAQSHE-EY
EDIAVKLGSDMEYLKMV-RARVWKQRICSPLFNTKQYTMDLEKLYLRMWEHYSKGNKPEH
--LV--QTVEASENA----
>gi|115660714|ref|XP_784504.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
----------MGDATTTTT-----------------------------------------
------------------------------------------------------------
-------------ATTGLAE-LAHREYQAGDYENAEKHCMQLWRQEPENTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPMLAEAYSNLG----NVFKEKGQLQEALENY-RH
AVRLKP--------------DFIDGYI--------NLAAALVAAADMEGAVQAYVTALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLDE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNSQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVG-AYLRALQ----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------KR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEQGKVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNVEGSIQLYCKALEIFPEFAAAHSNLASVLQQQGKLQEALLHYKEA
IRISPTFADAYSNMGNTLKEMQDIQGALQCYTRA--------------IQINPAFADAHS
NLAS-VHKDSGNIPEAIESYRTALKLKPNFPDAYCNLAHCLQIVCDWTDYESRMKRLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAARHGNLCLEKITV-------LHK
PAFNHPQDLTASGG-RLRVGYVSSDFGNHPTSHLMQ--SIPGKHSKDMVEIFCY-ALSPD
DNTSFRSKAMKEAEHFVDLSQIQCNGKAADRISADGIHVLVNMNGYTKGARNEIFALRPA
PIQVMWLGYPGTSGASFMDYLITDSVTSPMELASQYSEKLAFMRHTF----FIGDHWNMF
PHLLDKAIVEVKS-GSSRDNVAVINSINLKATLE--------KLGVATNGEVSN--GEKL
HFPVIE-SSTSQALHSLIQSGQVQGTI-NGITVCNGLALT----------------QSIP
KSATGEEVPSYPLITTRNMYGLPDDAIVFCNFNQLYKIDPATLRMWVNIIQKVPNSVLWL
LRFPAAGEPHLLATATQLGMPKGSLVFSAVA-SKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMITLP-----GETLASRVAASQLQTLGCPELIASSKQ-EY
EDIAIRLGTDIKFRQHI-RAKVWRRRVESPLFNTKMYAQSLELLYTKLWEKYEKGEPCDH
VDMSTMSPINGKINDTIKN
>gi|147899141|ref|NP_001091539.	Bos taurus
------------------------------------------------------------
------MASSVGNVADST------------------------------------------
------------------------------------------------------------
----------------GLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKLSDG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNVDSSNTAL
NMPVIPMNTIAEAVIEMINRGQIQITI-NGFSISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKNRQ-EY
EDIAVKLGTDLEYLKKI-RGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDH
--MI--KPVEVTESA----
>gi|89886173|ref|NP_001034837.1	Sus scrofa
------------------------------------------------------------
------MASSVGNVADSTE-----------------------------------------
------------------------------------------------------------
-------PTKRMLSFQGLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKLSDG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTAL
NMPVIPMNTIAEAVIEMINRGQIQITI-NGFSISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKNRQ-EF
EDIAVKLGTDLEYLKKI-RGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDH
--MI--KPVEVTESA----
>gi|66347873|ref|NP_001018115.1	Danio rerio
------------------------------------------------------------
------MASSVGNVADST------------------------------------------
------------------------------------------------------------
----------------GLAE-LAHREYQSGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPMLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-GYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGNVSEAEECYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVQLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VADQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINA-------LHK
PAYEHPKDLKASSG-RLRVGYISSDFGNHPTSHLMQ--SIPGMHNSEKFEVFCY-ALSPD
DGTNFRVKVMAEAHHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLAYPGTSGAPFMDYIVSDKATSPIEVAEQYSEKLAYMPNTF----FIGDHANMF
PHLKKKAVIDFKSNGHIFDNRIVLNGIDLKAFLESLPDVKVVKMEC--DGQEVADSNGAL
SMPIIPMNTAAEAIINMINQGQIQVTI-NGFTVSNGLATTQIFTVEEVVVSGTVALQINN
KAATGEEVPRTIVVTTRSQYGLPEDSIVYCNFNQLYKIDPPTLQMWANILKRVPNSVIWL
LRFPAVGEPNIQQYAQNLGLPASRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCPELIAQSRQ-EY
EDVAVKLGTDMEFLKKV-RARVWKQRICSPLFNTKQYTMDLEKLYLQMWENHASGGKPDH
--LVKMQSLETSEST----
>gi|91080933|ref|XP_974172.1|	Tribolium castaneum
----------------------------------------------------MAAITPVG
FLRLSAFELLAGPQSAKDM-----------------------------------------
------------------------------------------------------------
-------GHKAMGAIVALTCVLCYYNSCYCGFVFDDISAIKDNRDLRPHSPLL-NIFFND
FWGTPMHKEQSHKSYRPLCVLTFRWNYLLWQ-LEPMGYHLVNMLLHSVVCLMYFRMC-SM
FLPELS--------------SFVAAMLFAVHPIHTEAVTGVVGRAETLSSVFFLAAFMLY
AKA-------SKSKKSTGWKYLSFSMLSIATA-MLCKEQGITVAGVCAAYEIFVTQKVRL
PE-------------IKHVVKAAITAKSSYHLP----------WSSEATK-RLLVL----
----SATTMCLLLARLQIMGSQLPVFTRFDNPASVAPT-PA--RQLTYHYLISVNLWLLL
FPCNLCCDWTMGTIPLVETFADGRNLATIAAYTFFT------------------------
------------------------------------------------------------
------------------------ALLVTAYTTENRQQRT--------------------
-------------------------------------VILMSLALMALPFMPA-----SN
LFFPVGFVIAERVLYMPSMGFCMLVAYGWTVL-----AEKK--------GKKLAFFLLSI
LVVTHGTKTYLRNWDWEDEYSIFMSGLRVNQKNAKLFNNVGHALESQGKYEEALKFFKTA
VSVQEDDVGAHINVGRTYNHLKMFKEAEEAYLRAKSLLPKAKPGESYQARIAPNHLNVFL
NLANLISKNSTRLEEADMLYRQAISMRADYTQAYINRGDILIKLNRTKEAQEVYERAL--
----L-----YDSNNPDIYYNLGVVFLEQGKASQALAYLDKALEFDP----------EHE
QALLNSAILLQEFN-RPELRKIARE-------RLLK--LLDKDSNNERVHFNLG-MLAMD
EK----------------------NIEEAEHWFRRAVHLKADF-------RSSLFNLA--
---------------LLL-----ADDQRPLEAAPFLNQLVKYHPDHVKGLILLGD--IYI
NNIK-----DLDAAENCYRRILELDPENIQGLHNL----------C--------------
--------------VVHVERGKLLEAQ---------------------------------
-----ACLEKAHQLAPGEDYVLKHLQIVKNRIAKM-KLNPDEVET---------------
-------EKSRSQVVSNKSIDESDRKTRPVV-TGDSEE------------QR--------
---------------------------------YSSRVVNTEPMFVKNVDNIDYVDE-DL
GEVEFEEGMEQNVSNK--------------------------------WRHGKVGTDNDD
-------PSSGMS------
>gi|66524297|ref|XP_393964.2|	Apis mellifera
------------------------------------------------------------
-----MGVPARGALAA--------------------------------------------
------------------------------------------------------------
--------------IVAISAFAVYLNSLNCGFVFDDISAIKDNRDLRPHTPLK-NVFYND
FWGTPMHKEQSHKSYRPLCVLTFRWNYLIHQ-LDPMGYHLLNVILHIGVCLLYFRTC-LM
FLSDSA--------------TFVSSLLFAVHPIHTEAVTGVVGRAETLSSLFYLAALITY
TKC-------CRSRRSTGWKSLILSMFFVFTA-MLCKEQGITATAVCVFYEIFVVQKIRA
VD--------------IFLTLKAAFGGKKISLT----------WSSEGTK-RLTVL----
----TLVTFSLLILRLHVMGSKLPVFTRFDNPASVAPT-PI--RQLTYNYLAAVNLRLLF
LPSDLCCDWTMGTIPLIESFSDPRNLATIATHTTIL------------------------
------------------------------------------------------------
------------------------GLLITAI---LTPNRQ---TSI--------------
-------------------------------------ILIMSLAMMVLPFLPA-----SN
LFFPVGFVIAERVLYAPSMGFCMLIGYGWSIL-----CDKK--------FKKLTLFLLIT
LLAAHTTKTFMRNYDWLDEYSIFMSGLKVNDRNAKLFNNVGHALESQGKFKEALNFFNMA
VQVQGDDIGAHINVGRTYNHLKMFKEAEDAYLKAKSLLPKAKPGESYQARIAPNHLNVFV
NLANLIAKNATRLEEADLLYRQAISMRADYTQAYINRGDVLIKLNRTKEAQEVYERAL--
----F-----YDSNNPDIYYNLGVVFLEQGKASQALAYLDKALEFDP----------EHE
QALLNSAILLQELG-RAELRKVARE-------RLLK--LLRKDSNNERVHFNLG-MLAMD
DH----------------------DSGSAERWFRNAVALKEDF-------RSALFNLA--
---------------LLL-----ADEQRPLEAAPFLNQLVRFHPDHVKGLILLGD--IYI
NNIK-----DLDAAENCYRRILQLDPTNIQGLHNL----------C--------------
--------------VVMVERGKLGLAA---------------------------------
-----QCLERAAALAPHQDYVHRHLAIVKARISRLSPEQRDTEVFDDSFWQSGPKERNFN
MG-DISNSNSIGSTSGTSGL--NNMENSQFL-GKTDSV------------FSNHHNHI--
------GHKRNTD---STNHMVHLK-----SSSKPARVTLTEMK-----PEVKNTHI-DH
DKSSANLNNQQEYSSGN-FFNKNMNSDATELTIDRERAINSEKFDRTAPAFSTNGKHGTI
-------RRKDTALS----
>gi|125811561|ref|XP_001361920.	Drosophila pseudoobscura
------------------------------------------------------------
PCNRNREREVVVRGSSSQR-----------------------------------------
------------------------------------------------------------
-------NLLEFVCICVACI-ACYYNSTQCGLVFDDISAIRDNKDLRPHTPLR-NVFLND
FWGTPMRKEQSHKSYRPLTVMTFRFNYLLHA-LEPFGYHLVNLLLHLLVCLLWRRVC-RL
VLRQCAAVGSNAPSSSLNTCAFVASLLFAIHPVHTEAVTGVVGRAELLSSICFLAAFLSY
AKSVGDSGCT----RRTNWLGLFFCFGSCLSASMLCKEQGITIAGICVVYELFVVHQLRP
LH-------------LCNFVLRFFEEQPEQQSPKLGSVSGARRWSSSTLWKRLFFL----
----GGITVALLAGRVYVMGSQLPIFTRFDNPASAADT-PE--RQLTYGYLIYLNCWLLL
CPSLLCCDWTMGTVPLLEGFSDARNVTTLCTFLALG------------------------
------------------------------------------------------------
------------------------ALVAKACFTRNLAQSR--------------------
-------------------------------------TLLMCLGWMVLPFLPA-----SN
LFFPVGFVVAERILYMPSMGYCLLVAYGFEQL-----QRRW-----CLKWRIVGQVALCV
LLLSHALKTHQRNRDWRTEYSLFMSGVHVNQRNAKLYNNVGHALENEGGYEEALLYFQEA
VRIQTDDIGAHINVGRTLNNLKRYAEAEQAYVKAKALFPQAKPGVSYHARIAPNHLNVFI
NLANLIAKNQTRLEEADHLYRQAISMRSDYVQAYINRGDILMKLNRTAQAQEVYEQAL--
----L-----YDSENADIYYNLGVVFLEQGKSQQAQVYFNKAIELYP----------DHE
QALLNSAILLQELG-GEEARKVSRS-------RLYK--VLAKDDHNEKVYFNLG-MLAMD
ES----------------------SFEEAEQFFKRAIHLKSDF-------RSALFNLA--
---------------LLL-----ADTKRPLDAVPFLNQLIRHHASHVKGLILLGD--IYI
NHMK-----DLDAAEKCYRSILHYEPQNTQGLHNL----------C--------------
--------------VVFVERKRLAKAA---------------------------------
-----ACLQYAQRLAPAEDYIGRHLQIVHSRLQKINKLPESA------------------
--------------------PERQLAYE--------------------------------
----------------------------------------------------------DY
DPHEFKLPQDR----------------ASPLKSRKR------------------------
-------------------
>gi|46909607|ref|NP_631883.2|	Mus musculus
------------------------------------------------------------
------MASSVGNVADSTE-----------------------------------------
------------------------------------------------------------
-------PTKRMLSFQGLAE-LAHREYQAGDFEAAERHCMQLWRQEPDNTGVL-LLLSSI
HFQCRRLDRSAH-----FSTLAIKQNPLLAEAYSNLG----NVYKERGQLQEAIEHY-RH
ALRLKP--------------DFIDGYI--------NLAAALVAAGDMEGAVQAYVSALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETQPNFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALS----L
SPNHAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPHFPDAYCNLAN
ALKEKGSVAEAEDCYNTALRLCPTHADSLNNL-----ANIK-------------------
----------REQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA
IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSI
VAEQL-----EKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINV-------LHK
PPYEHPKDLKLSDG-RLRVGYVSSDFGNHPTSHLMQ--SIPGMHNPDKFEVFCY-ALSPD
DGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPA
PIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTF----FIGDHANMF
PHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNPDSSNTAL
NMPVIPMNTIAEAVIEMINRGQIQITI-NGFSISNGLATT----------------QINN
KAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWL
LRFPAVGEPNIQQYAQNMGLPQNRIIFSPVA-PKEEHV------------RRGQLADVCL
DTPLCNGHTTGMDVLWAGTPMVTMP-----GETLASRVAASQLTCLGCLELIAKSRQ-EY
EDIAVKLGTDLEYLKKI-RGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDH
--MI--KPVEVTESA----
>gi|148668308|gb|EDL00638.1|	Mus musculus
--------------------------------------------KISNERNAGAGGCRPA
DFKMVELDADLDHIVPSVL-----------------------------------------
------------------------------------------------------------
-------PPFWAKLVVGFVSLLCFARSYDGDFVFDDSEAIVNNKDLQSDTPLG-DLWHHD
FWGSKLSSNTSHKSYRPLTVLTFRINYYLSGGFHPVGFHVVNILLHGSISILMLDVF-SV
LFGGLQYTGKGQRVHLAPRASLLATLLFAVHPVHTECVAGVVGRADLLCALFFLLSFLGY
CQAFKETGNKEGTHSSTFWVLLSIFLGAVA---MLCKEQGITVLGLNAVFDILVIGKLDI
LA-------------AVRKVLHKDKSQENAGM-----------FKNGGLLFRIALL----
----TIGGTSMLYIRWKIMGTGPPAFTEVDNPASFADSMLV--RAINYNYYYSLNAWLLL
CPWWLCFDWSMGCIPLIKSVGDWRVIALAALWLCLI------------------------
------------------------------------------------------------
------------------------GLIFQALCSEDSCKRR--------------------
-------------------------------------ILTLGLGFLVIPFLPA-----SN
LFFRVGFVVAERVLYLPSAGYCVLLTFGFGAL-----SRHT-------KKKKPVAAIILG
ILLINALRCVIRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADQGNQTAAIKYYREA
VRLNPKYVHAMNNLGN--------------------------------------------
-----ILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEEAEQSYRTAI--
----K-----HRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKP----------EHS
LAWNNMIILLDNTG-NLAQAEAVGR-------EALQ--LI---PNDHSLMFSLANVLGKS
Q-----------------------KYKESEALFLKAIKANPNVASYH-------GNLA--
---------------------------------------VLYHRWGH-------------
----------LDSAKKHYEISLQLDP----------------------------------
------------------------------------------------------------
-----------VAVGTKENYSL-----LRRKLEQTQKKDV--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------
>gi|5052534|gb|AAD38597.1|AF145	Drosophila melanogaster
-------------------------------------MHVEQTRINMQSQGQSHQLPSAA
HILLDQNPNSTGSNLVVKQ-----------------------------------------
------------------------------------------------------------
-------NDIQSLSSVGLLE-LAHREYQAVDYESAEKHCMQLWRQDSTNTGVL-LLLSSI
HFQCRRLDKSAQ-----FSTLAIKQNPVLAEAYSNLG----NVFKERGQLQEALDNY-RR
AVRLKP--------------DFIDGYI--------NLAAALVAARDMESAVQAYITALQY
NPD------------------------------LYCVRSDLGNL-------LKALGRLEE
AK-------------ACYL--KAIETCPGFAVA----------WSNLGCVFNAQGE----
----IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI-FD--RAVA-AYLRALN----L
SPNNAVVHGNLACVYYEQGLID--------------------------------------
------------------------------------------------------------
-------------------------LAIDTY-------RR--------------------
-------------------------------------------AIELQPNFPDAYCNLAN
ALKEKGQVKEAEDCYNTALRLCSNHADSLNNL-----ANIK-------------------
----------REQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEA
IRIQPTFADAYSNMGNTLKELQDVSGALQCYTRA--------------IQINPAFADAHS
NLAS-IHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDIRMKKLVSI
VTEQL-----EKNRLPSVHPHHSMLYPLTHDCRKAIAARHANLCLEKVHV-------LHK
KPYNFLKKL-PTKG-RLRIGYLSSDFGNHPTSHLMQ--SVPGLHDRSKVEIFCY-ALSPD
DGTTFRHKISRESENFVDLSQIPCNGKAADKIFNDGIHILVNMNGYTKGARNEIFALRPA
PIQVMWLGYPGTSGASFMDYIITDSVTSPLELAYQYSEKLSYMPHTY----FIGDHKQMF
PHLKERIIVCDKQQSSVVDNVTVINATDLSPLVEN-TDVKEIK-EVVNAQKPVEITHKVA
ELP------NTTQIVSMIATGQVQTSL-NGVVVQNGLATT----------------QTNN
KAATGEEVPQNIVITTRRQYMLPDDAVVYCNFNQLYKIDPQTLESWVEILKNVPKSVLWL
LRFPAVGEQNIKKTVSDFGISPDRVIFSNVA-AKEEHV------------RRGQLADICL
DTPLCNGHTTSMDVLWTGTPVVTLP-----GETLASRVAASQLATLGCPELIARTRE-EY
QNIAIRLGTKKKKKK---------------------------------------------
-------------------
