>gi|125817345|ref|XP_696465.2|	Danio rerio
-------------------------------MAEQASGSTRPPQHDGVEQEQDRTDFL--
KLKQQLEMEFNQKRAKFKELYLSKEEELKRQ---------TAILEKAQAEMCSVQEELAD
AKAEMETIKAVATLSESTKQEAID---QVKQLWQEEVASLQAIMKDAE------------
--REFKLQFQQKLEQERAQWTQYRDGVE---REIA-------------------------
----ELRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMESEIAALKAKLSSSE-DRVK
---------------------------------ELEAAKVKELNHVLEAEKSCRTDLEMY
VAVLNTQKSVLQE----DAEKL------RKELH------EVVHLLELERQQHNQLKHTWQ
RANDQFLESQRLLMQDMQRIESVLSSEQLRQVEEIKKRDQEEDEQERLSQAKEASEDDGT
------------EHAEAVEDSLLGLSIEESHLSHSIHSSLHSLDAD------TPGRPDSS
DPYKDGLRRVQSTDSLGSSGGSLQPHGLGGHNNKAKSASQLDESDFGPLVGADCGGFDSM
DTSSISSLQPGHFLLTKDQEKAIKAMTPEQEETASLLSSISHTADTAYLPPSGYRLVSES
EWNLLQQELKNAGRKLGRRCDMCSNYEKQLQVIQGQEAETRDQVKKLQAILRQAN-DQLE
RTMNEKQELEDSVKQANEDTT---------------------AKISELKQKVQESESLFS
ALQQAF----SQAKRNTQEQMAVLLQSREQVSEEL---NRLQRDNESLQGKH-RLHMTLQ
QQEDFHMPTTVQELQKLVLQYREDIVSARTAAEHLEEKLKA----------EILFLKEQ-
---IQAEQCLKENLED--------------TLQLEIEGCKEEIASFSSLKTELERVKSEK
EQLESSLAEKSQMLESVQ----RLKNSLEE------------------------------
QLKDTLGSKSALETQVFEEKDKSQRLQAEL------------DVSEQVQRDFVKLSQTLQ
---------VQLERIRQAE---------------------SLDRIRA-------------
------ILNDTNLTDISQLPET--------------------------------------
----------------------------------
>gi|24650559|ref|NP_733203.1|	Drosophila melanogaster
--------------------MSTDDLLVRRERSEDSQSSSVSIPVTPTTGGAAPAPSAPT
SSLDRLRNTFRRTESISSQIFSHISTQFSNAAAAAASSEVIDGTTTYPYPDEPAPPVVPV
APDTVASASASSPSPSKLKAKRLKRARDTAEIERSNLVNICKLVVKEL------------
--LEQSLRYGRMLDSDHLPLQHFFIVIEHVLGHGL-------------------------
----RPKKGL----------LGPRKELWDLLQSVEHYCPEAQDITASVRDLPTVR-----
-------------------------------------THIGRARAWLRIALMQKKLSDYL
QALIEHREDSLFDYYEPHALMM------SDEIV------VIMGIL---------------
------------------------------------------------------------
---------------VGLNVIDCNLCVKEEDL-DSQQGVI--------------------
------------------------------------------------------------
-----------DFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQKNYI-----
-------------------EELNRHLNATVGNLQAKVESLTTTNALMKEDLAIAR-NSLL
ALQAENQAMRQSTSAGDNNST---------------------------------------
GSGGSS----DKDKEKASEELVEERRKNSELEKELKLQVSLKAESDMAMKLL-EKDIHEK
QDTIVSLRRQLDDIKQINLEMYRKLQDCKASLTHKTELMTKLEVQKEDMASTIDQLEKK-
---WSHDKSNLGEILKTTSQ----------TLTTQVTASEERA---ARAEAESRIEREWR
ISLQEKELKLKEKIANLQGCLKELSEEKE-------------------------------
RNGKLKADLDKVRTQWSEAQTTLEELGIQL------------SVSKLKVSEMQDQERRQR
----------QLLSGSAQSLQAMPEAVGSPGIWAPDSIATHCTACEREF--NLTR-RKHH
CRSCGEIFCKACSEH--TLPLLNAQGQPGKPVR-----VCDNCYAAK-------------
----------------------------------
>gi|93003178|tpd|FAA00172.1|	Ciona intestinalis
---------------------------------MPEYPTLCTTLKAMETLYLCNFKVSVD
GDWLCLKE----------------------------------------------------
-----------------ICDDNVT---TPNYLISSAIRGMAKLSVKGL------------
--IESSLSAGHTLDSDHVPLQQFFVIIEYVLRQGL-------------------------
----KAPKNF----------FMPNKYFWPPLEAIEKFNSEASEITSSVRSLPGIR-----
-------------------------------------THLGKGRAWLRLALMQKKLADYF
KILIDNK-AILSEWYDDGALIM------NDEAT------VLAGHL---------------
------------------------------------------------------------
---------------VGLNCIDANLCMKGDDL-DNQEMVI--------------------
------------------------------------------------------------
-----------DYSLYMKDGNHGNHGMFMEDD----NVEDEESQMQKLMDQKNYL-----
-------------------EERNRHLEDASVDLQKRSDHLEEENKSMLLEVEALK-IQIT
ELKNERVKMMDEKKDMTVTHQ---------------------KTLEIREKDLDTERETLR
KSKAGL----DEMYTQIQKQLKHETQMRMEVEKELELQMSLKSELDVAMKLL-EKDIFAK
QDGLVTLREQLDNVKAINMDVYNKLQAKSILEEEKNKTIAKLENETRSLAKKVSTLQQQ-
---IEEEERKTLVAREQAG-----------RYNQQLDDSENKR---GALVTNLQIEREWR
QSLEDQVGKLEQEKMLLEERLSVMEQMRE-------------------------------
ELRLVTTDRDDLRQTCHEQELTITDLAGHL------------GRSKQDLGDLKEVHKTMT
-----------------------------SSQWESDRQVTSCTQCEKAF--NLSR-RKHH
CRNCGLIYCNTCSDN--TMPLASS----AKPVR-----VCDTCHTTLLQRFSA-----SN
SAA-------------------------------
>gi|73955343|ref|XP_546569.2|	Canis familiaris
------------------MDVAVVYYSGVCEEIKSLYHNIVSLQQRVAELEKINAEFL--
RAQQQLEQEFNQKRAKFKELYLAKEEDLKRQ---------NAVLQAAQDDLGHLRTQLWE
AQAEVENIKAIATVSENTKQEAID---EVKRQWREEVASLQAVMKETV------------
--RDYEHQFHLRLEQERSQWAQYRESAE---REIA-------------------------
----DLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTETE-DKVK
---------------------------------ELEASKVKELNHYLEAEKSCRTDLEMY
VAVLNTQKSVLQE----DAEKL------RKELH------EVCHLLEQERQQHNQLKHTWQ
KANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKRDQEEDEQQRFHKKKEHNRTDVE
-----EEAKASAACALTHEEACAQLSNEEEHL-DSTHGSVHSLDADLLLPSGDSFSKSDT
DMFKDGLRRAQSTDSLGTSGS--LQSKALGYNYKAKSAGNLDESDFGPLVGADSVSENFD
TASLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSET
EWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQAMLRQAN-EQLE
RTARERQELEDALQRSTQDTG---------------------HQISALVLRAQASEILLE
ELQQGF----SQAKRDVQEQMAVLMQSREQVSEEL---ARLQKDNDSLQGKH-SLHVSLQ
QAEDFILPDTVEALRELVLKYRESIVHVRTAAEHTEEKLKA----------EILFLKEQ-
---IQAEQCLKENLEE--------------TLQLEIENCKEELASISSLKAELERIKVEK
GQLETTLREKSQQLEGLQ----EMRITLEE------------------------------
QLKKEAAAKVSVEQLMFEEKNKAQRLQTEL------------DVSEQVQRDFVKLSQTLQ
---------VQLERIRQAG---------------------SLERVRA-------------
------ILNDTKLTDINQLPET--------------------------------------
----------------------------------
>gi|91077810|ref|XP_970297.1|	Tribolium castaneum
-------------------------MKVQEIIEGGNNAMEQEMAGAQDTIYLCNFRVSVD
GEWLCLKELQDVEFNMQDSITQPLSTPSPDV-----------------------------
-----------------PVQPFGR---DPVVIERSNLVNISKLVVKEL------------
--IEQSLRYGRMLDSDHMPLQHFFIVLEHVLRHGL-------------------------
----RPKKGL----------LGPKKELWDILQMVEKYAPEAQDITASVRDLPTVR-----
-------------------------------------THMGRARAWLRLALMQKKLADYL
KVLIDHKDEALVEYFEPDALML------SDEAI------VIIGLL---------------
------------------------------------------------------------
---------------VGLNVIDCNLCVKEEDL-DCPQGVI--------------------
------------------------------------------------------------
-----------DFSLYLRSSNHVSSDSSNDEQG---------DNMTTVLDQKNYI-----
-------------------EELNRHLNATVTNLQSKVESLTTMNALMKEDLAIAK-NSLL
DLYEENRQLKQELGRDVSGYCMSS------------------SGVQITNVEPETNGKAVV
----------TGEVDELKQRLDEERKLRQEADKELELQMCLKAEMEVAMKLL-EKDIHEK
QDTIVSLRRQLDDIKLINLEMYKKLQECEASLKHKSELVTKLEAKAQSMTDTMQTLELK-
---FRESEANRATAEHLKR-----------ELDVQAAQHEEQT---SNVEGDLKVEREWR
ISLQETMQQDRERISKLQTEISQLKIIAQ-------------------------------
KYATLQEEYYNLKDKCLEQEQTLEELGTQL------------SKSKLQISDLKEEASRGK
---------T-------------------DGAWVQDKTATHCKACSKEF--NLTR-RRHH
CRNCGDIFCNACSDN--SMSLPSS----AKPVR-----VCDDCHTMLMGKYTVM------
----------------------------------
>gi|125811551|ref|XP_001361915.	Drosophila pseudoobscura
---------------------------MEENESPTDSRVSTVAANGDDDDATNQHTSIEQ
TEIRKMQNEFNTQRAKMRELYMQKEAEHAQS-----------------------MAERKK
LQDELDELKTHLMVADLKSENEMQ---LKDIKAQEEISSLQQLVQDTI------------
---EESSNYKSELERIKLELNKYQQQQQ---QQLQ-------------------------
----QIQVQV----------QQPQAE--SSGGLAPQMLNQVKRTLGSVRKLGSDSLNSSF
---------------------------------QQEDDSLRGSSNKGNGKQYASEDAEML
HSIVEQLQEEMKA--------L------KEKLR---------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------EQDGQLQSKSIAKQAVVTDMSAIHKSTSMDVAESS--------
-------------------CEACSVAQKTAEDLTANIKKQQKQVDLLQKQLVEAR-ETLG
REAALRKDLEDQWQEKREAHK---------------------SEVQNLREKSTANEQQLL
DMQQKF----LDTKDAVMRQLQRITDDRERVNKQL---ETLQADNDFLSGRY-LATSEEI
ENQYINLPNTVVELQELMLRQQSELIQARVSSEYEKQRCVS-------TLDEIQILRAQ-
---LEESNNERRTYKR--------------QTQLDIKSLQDRL---TEHLLTVQSYETTK
TQLERKEAELNKQLSESRV-----------------------------------------
EIIELQEANEKQNKTNADYKTKIKTLQEEL------------STMETVQKDFVKLSQTLQ
---------ISLEELRHADT---------EVRWQDDEDVNNCPTCHAGF--TVMV-RKIH
CRHCGHIYCDKCLTK--TVPSGPR----KRVAR-----VCDICHTLLTPNTAPYFSQGQP
PQQHHNQNQNHSQGQQQQSN--------------
>gi|76643458|ref|XP_874808.1|	Bos taurus
-----------------------------MAQPGPAPQPDVSLQQRVAELEKINAEFL--
RAKQQLEQEFNQKRAKFKELYLAKEEDLKRQ---------NAVLQAAQDDLGHLRTQLWE
AQAEMENIKAIATVSENTKQEAID---EVKRQWREEVASLQAVMKETV------------
--RDYEHQFHLRLEQERTQWAQYRESAE---REIA-------------------------
----DLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAE-DKIK
---------------------------------ELEASKVKELNHYLEAEKSCRTDLEMY
VAVLNTQKSVLQE----DAEKL------RKELH------EVCHLLEQERQQHNQLKHTWQ
KANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRLSKRKDHKKTDVE
-----EEVKIPVVCALTHEESSAQLSNEEEHL-DSTHGSVHSLDADLLLPSGDPFSKPDN
DVFKDGLRRAQSTDSLGTSGS--LQSKALGYNYKAKSAGNLDESDFGPLVGADSVTENFD
TASLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSET
EWNLLQKEIHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQVMLRQAN-DQLE
KTMKDKQELEDFIKQSTEDSS---------------------HQISALVLRAQASEILLE
ELQQGF----SQAKRDVQEQMAVLMQSREQVSEEL---VRLQKDNDSLQGKH-SLHVSLQ
QAEDFILPDTMEALRELVLKYRENIVNVRTAADHMEEKLKA----------EILFLKEQ-
---IQAEQCLKENLEE--------------TLQLEIENCKEEIASISSLKAELERIKVEK
GQLESTLREKSQQLESLQ----EMKMTLEE------------------------------
QLKKETAAKVTVEQLMFEEKNKAQRLQTEL------------DVSEQVQRDFVKLSQTLQ
---------VQLERIRQAD---------------------SLERIRA-------------
------ILNDTKLTDINQLPET--------------------------------------
----------------------------------
>gi|149030467|gb|EDL85504.1|	Rattus norvegicus
-----MEKQKPFTLFVPPRLSSSQVSAVKPQTAGGDSNYFKTVNKCTEGDFGVPLTMS--
-SLSKNRENIDTDPAFQKLSILPMLEQVANSGSCHYQEGVNDSDFENSEPMSRLYSKLYK
EAEKIKKWKVSIESELKQKENKLQ---ENRKIIEAQRKAIQELQFENE------------
---KVSLKLEEEIQENKDLIKENNATRHWCNLLKE-------------------------
----TCARSA----------EKTSKYEYEREETRQVYVDLNNNIEKMILAFEELR-----
---------------------------------------VQAENARLEMHFKLKEDHEKI
QHLEEEYQKEVNNKENQVSLLLIQSTEKENKMK------DLTFLLEESRDKANQLEEKTK
LQDENLKELNEKKDHLTSELEDIKMSMQRSMSTQKTLEEDLQIATKTIYQLTEEKEAQME
-----ELNKAKTTHSLVVTELKATTCTLEELL-RTEQQRLENNEDQLKLITMELQKKSSE
LEEMTKFKNNKEVELEELKTILAEDQKLLDEKKQVEKLAEELQGKEQELTFLLQ--TREK
EIHDLEVQVTVTKTSEEHYLKQVEEMKTELEKEKLKNIELTANCDMLLLENKKLVQ----
--------------EASDMVLELKKHQEDIINCKKQEERMLKQIETLEEKEMNLR-DELE
SVRKEFIQQGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKSKNIE
ELHQEN----KALKKKSSAENKQLNAYEIKVNKLELELASTKQKFEEMINNY-QKEIEIK
KISEEKLLGEVEKAKATVDEAVKLQKEIDLRCQHKIAEMVALMEKHKHQYDKIVEERDSE
LGLYKNREQEQSSAKV--------------ALETELSNIRNEL---VSLKKQLEVEKEEK
EKLKME-QENTAILTDKKDKKIQASLLESPEATSWKFDSKTTPSQNISRLS---------
SSMDSGKSKDNRDSLRASAKSILSTTVTKE------------YTVKTPTKKSIYQRENKY
---------LPTGGSNKKRKTVFEF----DVNSDSSETTDLLSLVSEED--ISNRIY-NN
NTPDSHLLVKTPKQTPLSLSTPASFTKFGSLKK-----MREDRWATIAKIDRKRRLK-EA
EKLFT-----------------------------
>gi|47605987|sp|P61584|ROCK1_PA	Pan troglodytes
---------------------------VAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIP
KAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQ
LKDEMEQKCRTSNIKLDKIMKELD---EEGNQRRNLESTVSQIEKEKM------------
-------LLQHRINEYQRKAEQENEKRRNVENEVS-------------------------
----TLKDQL----------EDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTES-DTAV
---------------------------------RLRKSHTEMSKSISQLESLNRELQERN
RILENSKSQTDKDYYQLQAILE---AERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLE
KVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIE
-----EAK------SVAMCEMEKKLKEEREAR-EKAENRVVQIEKQCSMLDVDL------
---------------------------------------KQSQQKLEHLTGNKE--RMED
EVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEF----
--------------ELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELK-EEIE
EKNRENLKKIQELQNEKETLA---------------------TQLDLAETKAESEQLARG
LLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMK
KAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQD-
---LRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASK
---ESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTR
>gi|149412132|ref|XP_001505794.	Ornithorhynchus anatinus
--------------------MAEEEAGVAPGPGSGPDSELGGGGGGEGEGEGEGCLAPRP
AERSREEKEKAPEEAGWSAPILSLAKKASEN-------------------LSAGYGNALK
SAVSLGGGGGGEGSAGTASKCQMM---EE----RSNLMNMMKLSVKVL------------
--IQSALSLGRSLDSDYPPLQQFFVVMEHCLKHGL-------------------------
----KVKKSF----------IGQNKSFFGPLELVEKLCPEASDIATSVKNLPELK-----
-------------------------------------TAVGRGRAWLYLALMQKKLADYL
KVLIDNK-HLLSEFYEPEALMV------EEEGA------VIVGLL---------------
------------------------------------------------------------
---------------VGLNVLDANLCLKGEDL-DSQVGVI--------------------
------------------------------------------------------------
-----------DFSLYLKDGQDIGGTEHEN--------------ITDVLDQKNYV-----
-------------------EELNRRLSCTVGDLQAKIDCLEKTNAKLQEEVSS---PPCS
XXXEEQLQLKKQNELIRERSE---------------------KSVEVTKQDTKVELETYK
QTRQGL----DELYSDVWKQLKEEKRVRAELEKELELQIGLKTEMEIAMKLL-EKDTHEK
QDSLVALRQQVEEVKAINLQMFQKAQNAESSLQQKSEAITSYEGKTCQVMTAMKQMEER-
---WRHSEKARQGAEEKNSKLKQEFGGQIEALRQQLSQLDKQC---SSLERELKSEKEQR
QTLQQELEREKDTTSLLKTELQQVDGLKQ-------------------------------
ELRKLQGEKEKLQNTCEEQEQALQEMGLHL------------SQSKLKMEDIKEVNKALK
-----------------------------GHTWLKDDEATQCKQCEKEF--SISR-RKHH
CRNCGHIFCNTCSSN--ELALPSY----PKPVR-----VCDACHTLLLQRCSS-----NS
S---------------------------------
>gi|157018777|gb|EAA06576.4|	Anopheles gambiae
--------------------------GKQPEPMEGEKEQTVEPSPAASAAKEESATAQ--
KELARMREEFNQQRARMKELYLAKENECKRH-----------------------AAEATA
ARKELEEAKAQLRIMEYSREKDAE---EQRNKVEDENRTLKQLVNETL------------
---DESSCMRESVQQLQDENGRLLEEIR--------------------------------
----QLKEEL-----------------ADSNQVSPSLAKTVQQAKKIILKLGAAD-----
-----------------------------------SSSCDNLEESMRKVKKYAQEDAEVL
RSLVVPLEEEIKS--------L------KEKLR---------------------------
------------------------------------------------------------
---------------LAYEEIETYSATRE-------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------PAEKPCERCAAHEAALA---RQQEEERKRTAGWEKSLQRLR-EQVA
KEAALRADPEVQWHKKREEHK---------------------NEVQKLTDWATETERALD
KLRREY----GQLKVALRDELQKLTQEREHVCYRL---NGLQQDNDFLSGKY-VASSDAL
KDQEINLPQSIEELQELVLTLHENLIVTKAGCEFAERKARS-------MQDEVALLQEQ-
---QHCRDREAKKAEQ--------------HYHQKQHQLHEQL---RKQQHDFQLLDSLR
SELECAEVEHKKQNSELRM-----------------------------------------
QIIELQAANERLDRQNGDLRSKMTVLQEDL------------ANNEAVQKDFVKLSQSLQ
---------MQLEKIRSADT---------QVRWQDDDDVDQCPNCKKEF--TVTR-RKQH
CRHCGTIYCQPCLGK--SVPSGPN----RKPAR-----VCDVCHTLLVQDTAPYFSR-EP
PQSP------------------------------
>gi|45597449|ref|NP_035646.1|	Mus musculus
-----MEKQKPFTLFVPPRLSSSQVSAVKPQTAGGDSNYFKTVNKCTEGDFGVPFTMS--
-----SRENIDKDPAFQKLSILPMLEQVANSGSCHYQEGVNDSDFENSEPMSRLYSKLYK
EAEKIKKWKVSIESELKQKENKLQ---ENRKIIEAQRKAIQELQFENE------------
---KVSLKLEEEIQENKDLIKENNATIHWCNLLKE-------------------------
----TCARSA----------EKTNKYEYEREETRQVYVDLNSNIEKMILAFEELR-----
---------------------------------------VQAENARLEMHFKLKEDHEKI
QHLEEEYQKEVNNKENQVSELLIQSAEKENKMK------DLTFLLEESRDKANQLEEKTK
LQDENLKELSEKKDHLTSELEDIKMSMQRSMSTQKALEEDLQIATKTISQLTEVKEAQME
-----ELNKAKTTHSFVVTELKATTCTLEELL-RTEQQRLEKNEDQLKLITVELQKKSNE
LEEMTKFKNNKEVELEELKNILAEDQKLLDEKKQVEKLAEELQEKEQELTFLLE--TREK
EVHDLQEQVTVTKTSEQHYLKQVEEMKTELEKEKLKNTELTASCDMLLLENKKFVQ----
--------------EASDMALELKKHQEDIINCKKQEERLLKQIENLEEKEMHLR-DELE
SVRKEFIQQGDEVKCKLDKSEENARSIECEVLKKEKQMKILESKCNNLKKQVENKSKNIE
ELHQEN----KTLKKKSSAEIKQLNAYEIKVSKLELELESTKQRFEEMTNNY-QKEIENK
KISEGKLLGEVEKAKATVDEAVKLQKEIDLRCQHKIAEMVALMEKHKHQYDKIVEERDSE
LGLYKNREQEQSSAKI--------------ALETELSNIRNEL---VSLKKQLEIEKEEK
EKLKMA-KENTAILKDKKDKKIQASLLESPEATSWKFDSKTTPSQNISRLS---------
SSMDSGKSKDNRDNLRASAKSILPTTVTKE------------YTVKTPTKKSIYQRENKY
---------IPTGGSNKKRKTAFEF----DVNSDSSETADLLSLVSEED--VSNRLY-DN
NPPDSHLLVKTPKQTPLSLSTPASFMKFGSLKK-----MREDRWTTIAKIDRKRRLK-EA
EKLFS-----------------------------
>gi|126272594|ref|XP_001369199.	Monodelphis domestica
MAFRRRSSIPSTWAELRFHDIDEEHNRKASLTSSWSAPKRAAGRRRKARVRTATKDFQCP
NGVFLLDRGMPWSSLGFGKVIWAALRKVWRE-------------SPPQSPQSEPLTRPGR
IGVLVQLSLAFISQNTFISPSTVK---DPTAVERANLLNMAKLSIKGL------------
--IESALSFGRTLDSDYPPLQQFFVVMEHCLKHGL-------------------------
----KVRKSF----------LSYNKTIWGPLELVEKLYPEAEEIAASVRDLPGLK-----
-------------------------------------TPLGRARAWLRLALMQKKMADYL
RCLIIQR-DLLSEFYEYHALMM------EEEGA------VIVGLL---------------
------------------------------------------------------------
---------------VGLNVIDANLCVKGEDL-DSQVGVI--------------------
------------------------------------------------------------
-----------DFSMYLKNEEDIGSKERNVQ-------------IAAILDQKNYV-----
-------------------EELNRQLNSTVSSLHSRVDSLEKSNTRLIEELAIAK-NNII
KLQEENHQLRSENKLILMKTQ---------------------QHLEVTKVDVETELQTYK
QSRQGL----DEMYNEARRQLREEAQLRQDVENELMVQVSMKHEIELAMKLL-EKDIHEK
QDTLIGLRQQLEDVKAINIEMYQKLQGSEEGMKEKNEIIGRLEDKTNKITAAMKQLEQR-
---LQQAEKAQMEAKNEDEKFEQECLSQSDSLQKQICQKETQL---AQLETDLKIEKEWR
QTLQEDLQRESEALCQLRSETRHITSLKK-------------------------------
EFLSLQNENRQLKRVSRDQEQALQELGNKL------------SESKLKIEDIKEANKALQ
-----------------------------GQVWLKDEDATHCKLCEKEF--SLSK-RKHH
CRNCGEIFCNACSDN--ELPLPSS----PKPVR-----VCDSCHALLIQRCSS-----TG
P---------------------------------
>gi|108870996|gb|EAT35221.1|	Aedes aegypti
----------------------------QQEELDRNLGNEVPAKVAGETAPEAEKSRELQ
LELKRIRDEFNQQRAKMKELYLAKEAECKRF-----------------------SKEAAA
VRKELDEAKSQIMVMEYNREKDLE---EQNRRAQEEIHTLQQLVQETV------------
-----------------DESAFSNGEVRRLAEENE-------------------------
----RLRTEQ----------QELKEALAAAQQDTPSLAPVLNQAKKIIRKLGAAD-----
-----------------------------------SNSHDNLEDSMRKVNKYAQEDAEVL
RSLVVPLEEEIKT--------L------KEKLR---------------------------
------------------------------------------------------------
---------------DAYEELEKHPPKEPNPD----------------------------
------------------------------------------------------------
-----------------------NPQEPSTNNPSP-------------------------
-------------------CEMCSNYESKLVHCQEQINGEKQKVQQLEKSVERMK-EELA
KEGAMRADLEAQWQLKREDHK---------------------AEVQRLNEQTAKAEQELA
ALRKDY----GQLKQTVNDELQKLTEEREQVTE--------------AGGKR--------
----GFLFKYLQTTRTLTLTARLTVILLPLSRGTPRNMLCE------GHADEVTLLRDQ-
---QHIREREVRRAER--------------DYSNKVAQLEEQL---RQQYQHYQRLAAHK
EELERADADNKRQISELRM-----------------------------------------
QTIELQATNEKLDKHNVDLKNKMSVLQEDL------------ANNEAVQKDFVKLSQSLQ
---------MQLEKIRSADT---------QVRWQDEEDIDQCPNCRKEF--TVTR-RKQH
CRHCGTIYCPPCLTK--TVSMGTN----RRPAH-----VCDVCHTLLVQDTAPYFSR-EP
PQSP------------------------------
>gi|45384236|ref|NP_990388.1|	Gallus gallus
-----------------------------MAQPGPSAPTDVALLQRVAELEKVNAEFL--
RTKQQLEQEFNQKRAKFKELYLAKEEDLKRQ---------NAVLQAAQDDLGQLRTQLME
AHAEMENIKAIATVSENTKQEAID---EVKRQWQEEVASLQAIMKETV------------
--RDYELQYHHRMEQERAQWNQYRENVE---REIA-------------------------
----ELRRRLSEAQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKEKLIEAE-EKIK
---------------------------------ELEASKVKELNHYLEAEKSCRTDLEMY
VAVLNTQKSVLQE----DAEKL------RKELH------EVCHLLEQERQQHNQLKHTWQ
KANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDDQQRLSKRKEQKQKDSD
-----DETKAS--CSLAHEESLTQFSNEEVHL-NSTHSSVHSLDADLLLSSGESFNKSEN
DMFKDGLRRAQSTDSLGTSGS--LQSKALGYNNKAKSAGNLDESDFGPLVGADSVSENYD
TASLGSLQMPSGFMLTKDQEKAIKAMTPEQEETASLLSSVTQGVESAYVSPSGYRLVSET
EWNLLQKEVQNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQVMLRQAN-DQLE
KTMKDKQELEEYMKQSAEDSS---------------------NQISLLMVKCQKSENFLN
ELQQAF----SQAKRSVQEQMAVLTQSREQVSEEL---VRLQKDNESLQGKH-SLHVSLQ
QAEDFILPEAAEELRELILKYREDIISVRTAADHLEEKLKA----------EILFLKEQ-
---IQAEQYLQENIEE--------------TLQLEIENCKEEIASISSLKAELERIKVEK
EQLESSSQEYLQQLESLQ----ETKNTLEE------------------------------
QLKKETAAKANLEQLVFEEKNKAQRLQTEL------------DVSEQVQRDFVKLSQTLQ
---------VQLERIRQAD---------------------SLERIRA-------------
------ILNDTKLTDINQLPET--------------------------------------
----------------------------------
>gi|149724871|ref|XP_001502902.	Equus caballus
-------MYGSASFRYERGLDYDFSIVLRKHFEIGRVVQAVSLQQRVAELEKINAEFL--
RAQQQLEQEFNQKRAKFKELYLAKEEDLKRQ---------NAVLQAAQDDLGHLRTQLWE
AQAEMENIKAIATVSENTKQEAID---EVKRQWREEVASLQAVMKETV------------
--RDYEHQFHHRLEQERTQWAQYRESAE---REIA-------------------------
----DLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAE-DKIK
---------------------------------ELEASKVKELNHYLEAEKSCRTDLEMY
VAVLNTQKSVLQE----DAEKL------RKELH------EVCHLLEQERQQHNQLKHTWQ
KANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRLNKRKDHKKTDVE
-----EEVKIPVVCALTHEESSAQLSNEEEHL-DSTHGSVHSLDGDLLLPSGDPFSKSDN
DVFKDGLRRAQSTDSLGTSGS--LQSKALGYNYKAKSAGNLDESDFGPLVGADSVSENFD
TASLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYRLVSET
EWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQVMLRQAN-DQLE
KTVKDKQGLEDFIKQSAGDSS---------------------HQISALALRAQASEILLE
ELQQAF----SQAKRDIQEQMAVLMQSREQVSEEL---VRLQKDNDSLQGKH-SLHVSIQ
QAEDFILPDSVEALRELVLKYRENIVNVQTAADHVEEKLKA----------EILFLKEQ-
---IQAEQCLKENLEE--------------TLQLEIENCKEEIASISSLKAELERIKIEK
GQLESTLREKSQQLESLQ----EMKVTLED------------------------------
ELKKESAAKVTIEQLMFEEKNKAQRLQTEL------------DVSEQVQRDFVKLSQTLQ
---------VQLERIRQAD---------------------SLERIRA-------------
------ILNDTKLTDINQLPET--------------------------------------
----------------------------------
>gi|47218705|emb|CAG05677.1|	Tetraodon nigroviridis
-------------------MASADHDLVLSEADGSREKGQVFGVLRLQEEKSGSGDKAST
TARGGGGGGGGGGDGRWQAPIFALARKASET----------------ISGSIHVLPKVSE
---------HRTSLPGDWAVQALR---DPMTMERANLLNMAKLSIKGL------------
--IESALSFGRTLDSDYPPLQQFFVVMEHCLKHGL-------------------------
----KVKKSF----------LGFNKSLWGPLELVEKLCPEAAEISASVRDLPGLK-----
-------------------------------------TPLRRARAWLRLALMQKRLADYL
RLLI-TRKDLLSDFYETSALML------EEEGA------VIVGLL---------------
------------------------------------------------------------
---------------VGLNVIDANLCVKGEDL-DSQVGVI--------------------
------------------------------------------------------------
-----------DFSLYLRNDVDDYRGEERYGTPSG----------AAVLANTALDV----
-------------------TELPFPWQQEQPDCFYFGPEELCGGAEPSAKLAIAK-NNII
KLQEENQHLRSENSLILLKSQ---------------------QQLEVTQGDVSVERDTYK
QSRQGL----DEMYNEARRQLKEECQLRQDVENELVAQVSMKQEMELAMKLL-EKDIHEK
QDTLIGLRHQLDEVKAINVEMYQKMQASDDEMKKKNNMISRLEEKTNQITATMKQLEQR-
---LQEAERHRGSAEEGTRRFKLDFANKADSLQRRIEHREKQL---QQLETDLKIERQWR
QTLQKDLDREKDTVAQLSTEALQISALKKVESQGPAGLGPAHPPLTHRSPTAVSVLLCVQ
EFHRLQDENLQLKSVCGDQEQALEELGSKL------------SESKMKIEDIKEANKALQ
-VEWRRSPRCWCGSLRPVGDASVDRLFQGGQVWLKDKDASRCKLCEKEF--SISR-RKHH
CRNCGEIFCNGCSDN--ELPLPAS----PKPVR-----VCDTCHALLLQRCSS-----NA
T---------------------------------
>gi|58331917|ref|NP_001011070.1	Xenopus tropicalis
-----------------------------MAEYGNVVRPDAALQQRVQELERDNAEFH--
RTKQLLELEFNQKRAKFKELYLAKEEDLKRQ---------QAVIQVAQEEIVQLNVHLSQ
ARAEMENIKAVATVSENTKQEAID---EVKKQWQEEVASLQAIMKDTV------------
--REYEIQFHHRLEQERAQWGQYRESVE---REIA-------------------------
----ELRRRLSEGQQEENLESDMKKAQEDAEKLRSVVMPMEKEIGTLKEKLTEAE-EKIK
---------------------------------ELEASKMKELNHYLEAEKSCRTDLEMY
VAVLNTQKSVLQE----DAEKL------RKELH------EVCHLLEQERQQHNQLKHTWQ
KANDQFLESQRLMMQDMKRMESVLTTEQLRQVEESKKKDQEEEQRTRKRKEKETVQKEEE
------------YTKVILEESVSNLKQEEQI--NSLHGSIHSLDTDIMLHEGDSFNK-QE
DLFKDGLRRAQSSDSLGASGP--MQTKTLGHNNKAKSAGNLDESDFGPLVGADSVSENFD
TSSLGSLHMPSGFMLTKDQEKAIKAMTPEQEETASLLSSVTQTLECTYVPPSGYRLVSET
EWNLLQKEVQTAGNKLGRRCDMCSNYEKQLQGIQTQEAEIRDQVKKLQSMLRQVN-DQLE
KTLKDKKDLEDYMKQNTEETS---------------------TQISTLTIRTNQSETLLA
DLQQAF----TQAKRNIQDQMAVLMHSREQVSEEL---LRLQRDNESLQGKH-SLHVSLQ
QAENFSLPETSEELQNLVLKYREDIISVRTAADHLEEKLKA----------EILFLKEQ-
---IQAEQCQKENIEE--------------TLQIEIENCKEEIASTSSLKLELDRVKAER
EQLEASLQEKTRELQNLQ----TLKDSLED------------------------------
QLKKETGGKASLEQLVFEEKNKAQRLQTEL------------DVSEQVQRDFVKLSQTLQ
---------VQLERIRQTD---------------------SLEAIRA-------------
------ILNDTKLTDINQLPET--------------------------------------
----------------------------------
>gi|119577025|gb|EAW56621.1|	Homo sapiens
-----MEKQKPFALFVPPRSSSSQVSAVKPQTLGGDSTFFKSFNKCTEDDFEFPFAKT--
-NLSKNGENIDSDPALQKVNFLPVLEQVGNS-DCHYQEGLKDSDLENSEGLSRVYSKLYK
EAEKIKKWKVSTEAELRQKESKLQ---ENRKIIEAQRKAIQELQFGNE------------
---KVSLKLEEGIQENKDLIKENNATRHLCNLLKE-------------------------
----TCARSA----------EKTKKYEYEREETRQVYMDLNNNIEKMITAFEELR-----
---------------------------------------VQAENSRLEMHFKLKEDYEKI
QHLEQEYKKEINDKEKQVSLLLIQITEKENKMK------DLTFLLEESRDKVNQLEEKTK
LQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQME
-----ESNKARAAHSFVVTEFETTVCSLEELL-RTEQQRLEKNEDQLKILTMELQKKSSE
LEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQ--AREK
EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQ----
--------------ETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRQNELE
YVREELKQKRDEVKCKLDKSE---------------------ENCNNLRKQVENKNKYIE
ELQQEN----KALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTY-QKEIEDK
KISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSE
LGLYKSKEQEQSSLRA--------------SLEIELSNLKAEL---LSVKKQLEIEREEK
EKLKREAKENTATLKEKKDKKTQTFLLETPE-IYWKLDSKAVPSQTVSRNF---------
TSVDHGISKDKRDYLWTSAKNTLSTPLPKA------------YTVKTPTKPKLQQRENLN
---------IPIEESKKKRKMAFEF----DINSDSSETTDLLSMVSEEE--TLKTLYRNN
NPPASHLCVKTPKKAPSSLTTPGSTLKFGAIRK-----MREDRWAVIAKMDRKKKLK-EA
EKLFV-----------------------------
>gi|3024609|sp|Q15431|SYCP1_HUM	Homo sapiens
-----MEKQKPFALFVPPRSSSSQVSAVKPQTLGGDSTFFKSFNKCTEDDLEFPFAKT--
-NLSKNGENIDSDPALQKVNFLPVLEQVGNS-DCHYQEGLKDSDLENSEGLSRVFSKLYK
EAEKIKKWKVSTEAELRQKESKLQ---ENRKIIEAQRKAIQELQFGNE------------
---KVSLKLEEGIQENKDLIKENNATRHLCNLLKE-------------------------
----TCARSA----------EKTKKYEYEREETRQVYMDLNNNIEKMITAHGELR-----
---------------------------------------VQAENSRLEMHFKLKEDYEKI
QHLEQEYKKEINDKEKQVSLLLIQITEKENKMK------DLTFLLEESRDKVNQLEEKTK
LQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQME
-----ESNKARAAHSFVVTEFETTVCSLEELL-RTEQQRLEKNEDQLKILTMELQKKSSE
LEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQ--AREK
EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQ----
--------------ETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLR-NELE
YVREELKQKRDEVKCKLDKSE---------------------ENCNNLRKQVENKNKYIE
ELQQEN----KALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTY-QKEIEDK
KISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSE
LGLYKSKEQEQSSLRA--------------SLEIELSNLKAEL---LSVKKQLEIEREEK
EKLKREAKENTATLKEKKDKKTQTFLLETPE-IYWKLDSKAVPSQTVSRNF---------
TSVDHGISKDKRDYLWTSAKNTLSTPLPKA------------YTVKTPTKPKLQQRENLN
---------IPIEESKKKRKMAFEF----DINSDSSETTDLLSMVSEEE--TLKTLYRNN
NPPASHLCVKTPKKAPSSLTTPGPTLKFGAIRK-----MREDRWAVIAKMDRKKKLK-EA
EKLFV-----------------------------
>gi|109089608|ref|XP_001083568.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
--------------------MATK---DPTAVERANLLNMAKLSIKGL------------
--IESALSFGRTLDSDYPPLQQFFVVMEHCLKHGL-------------------------
----KVRKSF----------LSYNKTIWGPLELVEKLYPEAEEIGASVRDLPGLK-----
-------------------------------------TPLGRARAWLRLALMQKKMADYL
RCLIIQR-DLLSEFYEYHALMM------EEEGA------VIVGLL---------------
------------------------------------------------------------
---------------VGLNVIDANLCVKGEDL-DSQVGVI--------------------
------------------------------------------------------------
-----------DFSMYLKNEEDIGNKERNVQ-------------IAAILDQKNYV-----
-------------------EELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAK-NNII
KLQEENHQLRSENKLILMKTQ---------------------QHLEVTKVDVETELQTYK
HSRQGL----DEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKLL-EKDIHEK
QDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLEEKTNKITAAMRQLEQR-
---LQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQL---VQLETDLKIEKEWR
QTLQEDLQKEKDALSHLRNETQQIISLKK-------------------------------
EFLNLQDENQQLKKIYHEQEQALQELGNKL------------SESKLKIEDIKEANKALQ
-----------------------------GLVWLKDKEATHCKLCEKEF--SLSK-RKHH
CRNCGEIFCNACSDN--ELPLPSS----PKPVR-----VCDSCHALLIQRCSS-----NL
P---------------------------------
>gi|115770453|ref|XP_789966.2|	Strongylocentrotus purpuratus
---------------------------------MDIEGEVLNVQQRVGDLESSLQAVL--
QEKKLQEEDFAQKRAKFKELYLTREQELIKE-------------------VDNIREEKDR
LSEELAGLNTAASVIESSKDEEIA---EIKQKWTDEVASLQQIVSHTAAITAEETAMTYL
MERDKLLALNDKLTQELQELSQYPAGEKTMTSSGSAGLLTSMTKSFRNLTSTTTSPSPTR
EEKPSLPPTPVSPSAQDNLEQSMLKAQKDSEMLRAVVVPLEREIESLKQKLSDVGSDNRR
LHARLKKATGSKDYSDAVPTPDHYGYEVTKDDIDILNEKIRDLNKVLETEKAARTDLELY
VAVLGKQKHVMQD----EGDQM------RDELK------DVCSILEQEKQAHSQLQQTWQ
MANDQFLESQRLQMMDMRRMESVLTEEQQRQIGEVLKKDQEREEQEKKVRVLQEKRESLE
KRHSKETAEQEPTQQVPPAQTNSSLLLSRDDI-EDSDDALLVPSSMDTPNSSTPSRLHPS
INFVGPNVDPEEL----------LQFDTTDSSGGAKTTVHGSISEIGAQSGHNT--SDML
GTSYDSVSLCSNISLTEAQERAI-SGTPESEEMKSVLASARSKTD-LYSLLAGKRVVSDT
EWTKLQEEVRFAREKLGRPCDLCTNYEQQLQSLQTKYSESLESSRTLRQQLEQEI-DNVL
REQKIRSELEESLKNAAEDAQ---------------------IQIKTLTTKNGESEELLS
NLRLQY----SKSQNEIHSQMQILIESREQLYQEV---MKLQKENDSLSAKR-SLHQSLQ
SSEPFDLPTSPQELSHLCMKYRDDIITVRVNADHTESSLRS----------ELSFTKEQ-
---LSSEQHQRMTMED--------------TYQTELDDYKEELLVFRNLREEYEKEKKAR
GEVEETLKEVQESKKSMQGKSKEVITTLRE------------------------------
QVEELSAHKANIEADLQDRRNKVQNLQLEL------------ENSEAVQKDFVKLSQSLQ
---------VQLEIIRQKDN---------EVRWQHEDDADKCNNCKTAF--GSSKKKKNH
CKHCGKLFCADCVTK--SVESGPR----RRKMP-----VCDVCHTLLVNESAPYFSK-EA
PDNT------------------------------
