>gi|37651167|dbj|BAC98943.1|	Oncorhynchus masou
------------------------------------------------------------
-MSRNLSLLRPPLVGVTGSMQP------ALSNMSQFPPLVDWEAP--------------T
FTRAAQFRVSATLILFLFAACSNLALL-----VSVC-RGRGR-RLA---SHLRPLIMSLA
AADLMMTFVVMPLDAIWNITVQWYGGD---AMCKMLCFLKLFAMHSSAFILVVVSLDRHH
AILHPL---E-SLNSHHRNKRMLGLAWGLSVLLALPQLFIFRAIKA-------------E
GVD------------------FTQCVTHGSF---------------------------KE
RWQETVYNMFYFVTLYVFPLLVMSFCYTHILIEINQQLHRN-------------------
---------KAGES--CLRRSGTDMIPKARMKTLKMTIIIVMSFVV--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|37359724|dbj|BAC97836.1|	Oryzias latipes
------------------------------------MNESSCCHPPAITYQQS-------
-SRWDLNASCDWSAPRCN-WTS---------------GDGPLQLP--------------T
FSTAAKVRVITTFILCGVSTLCNSAVL-----WAAI---GH--KRK---SHVRVLIINLT
AADLLVTFIVMPVDAAWNITVQWLAGD---AACRFLMFLKLQAMYSCAFVTVVISLDRQS
AILRPL---S-ISAAPRRNRSMLTVAWTMSAVLSVPQMFIFHNVTI-------------T
HPA----------------N-FTQCTTRGSF---------------------------VT
HWQETAYNMFTFTCLFLLPLSIMIICYTRIFIQISKQMTKK-------------------
-------NVSSDEP--HLRCSKNN-IPKARMRTLKMSVVIVVGFIVCWTPYYLLGLWYWF
FPDDL-EGK---VSHSLTHILFIF--GLFNTCLDPIIYGLFTTR---FHRGRRKCY-GGA
TATL--------------SLESKVVTAEAVKRSSDASASRG----------DAG------
-----------------------------------------EKDNNSARTERQSSGGNI-
-----------
>gi|6754032|ref|NP_034453.1|	Mus musculus
-----------------------------------------------------------M
ANNASLEQDPNHCSAINNSIPL-----------------IQGKLP--------------T
LTVSGKIRVTVTFFLFLLSTAFNASFLLKLQKWTQK---RKKGKKL---SRMKVLLKHLT
LANLLETLIVMPLDGMWNITVQWYAGE---FLCKVLSYLKLFSMYAPAFMMVVISLDRSL
AITQPL---A-VQSNSKLEQSMISLAWILSIVFAGPQLYIFRMIYLAD----------GS
GPT----------------V-FSQCVTHCSF---------------------------PQ
WWHQAFYNFFTFGCLFIIPLLIMLICNAKIIFALTRVLHQD-------------------
----------PRKL--QLNQSKNN-IPRARLRTLKMTVAFATSFVVCWTPYYVLGIWYWF
DPEML--NR---VSEPVNHFFFLF--AFLNPCFDPLIYGYFSL-----------------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|38230726|gb|AAR14318.1|	Manduca sexta
------------------------------MANGGNNTTLYSDLLFTSDPTLHQDFSVDG
SIYTNHQVVWPIEKCIDEHLINDSNIDISKMYMYNGSLVSCLEHA-------------PI
LTKSTVIRASVLSAMAILSFFGNLATI-----ISIQRGKRGRGRARPSWTAIYSLIFQLS
IADLLVTIFCIAGEAAWSFTVQWYAGN---IACKIFKFLQMFALYQSTFILVLIGVDRWL
AVKYPM---K-SMATATRSGRLVVIAWVLSVVLSIPQTVVFRVAKG-------------P
FVE----------------E-FYQCVTHGFY---------------------------TE
RWQEQAYTTLSLVFMFVLPLVILISTYVSTVRTIARSEKVF-------------------
-----KPEVRRQEKYFTPDMNRRRLIDRAKMKSLRMSVVIVAAFLVWWAPYYVMMIIFTF
LNPD---KD---QSEELLSGIFFF--GMSNSLVNPVIYGAFHL----WPKKKRSHR-HSD
RESG--------------GHHASLLRRGDNNTSSIRLTTIR-------------------
------------------------------------------SLRSSAKYSNGHNISLL-
-----------
>gi|109097601|ref|XP_001116798.	Macaca mulatta
------------------------------------------------MDSMRFSAGPDA
GPSGNSSLWWPLATSAGNTSRE------------AEALGEDNGPP-----------RDVR
NEELAKLEIAVLAVTFTVAVLGNSSVL-----LALH---RTP-RKT---SRMHLFIRHLS
LADLAVAFFQVLPQMCWDITYRFRGPD---WLCRVVKHLQVFGMFASAYMLVVMTADRYI
AVCHPL---KTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEV-------------N
NVT----------------K-ARDC--WATF---------------------------IQ
PWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWRNVRGK-------------TASRQS
KGAAQAGAAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVW
DPKSVWTES---ENPTITITALL---GSLNSCCNPWIYMFFSGH---LLQDCVQSF-PCC
QNIK--------------EKFNKEDTDSMSRRQTFYSNNRS-------------------
------------------------------------------PTNSTDKKMRTG------
-----------
>gi|119892405|ref|XP_580347.3|	Bos taurus
------------------------------------------------MDSMRFSGSPSA
EPASNSSRWWPLTAGGANTSGD------------SEALGEDGGPQ-----------ADTR
NEELAKLEIAVLAVIFVVAVLGNSSVL-----LALH---RTP-RKT---SRMHLFIRHLS
LADLAVAFFQVLPQLGWDITYRFRGPD---GLCRVVKHMQVFAMFASAYMLVVMTADRYI
AVCHPL---KTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSVVEV-------------S
NVT----------------K-TYDC--WANF---------------------------IQ
PWGLPAYVTWMTGSVFLAPMVILGTCYGFICHHIWGNVRGK----------TAGRQGTGA
PAEGAGEGALHRGVLHARCVSSVKTISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSAW
DKNFSWVES----ENPATAIPALL--ASLNSCCNPWIYMFFSGH---LLQDCAQSF-PCC
QNVK--------------RTFTRENSDSMNRRPTSFTNTRS----------PTN------
----------------------------------SMGTWKGSPKSSKSIKFIPVST----
-----------
>gi|108872369|gb|EAT36594.1|	Aedes aegypti
------------------------------MSNAILKTERDEVLNYSHSYGENYNNDVNT
MPYVLSSSTSKTGVFDNETWYG------------TNSSNWNEPLP-----------IDMQ
FNDGHKLQIVVYSVLMVISAIGNITVL-----ALLI---KRRLKSH---SRIDMMLTHLA
IADLLVTFLMMPLEIGWAATVQWRAGD---IMCRVMAFFRTFGLHLSSFVLVCISVDRYY
AVLQPL------NLSKSRGKIMILIAWAMATLCSAPQPFIFHVEIH-------------P
NHT----------------W-YEQCVTYNTF---------------------------SN
DNYHTVYNILVMMFMYALPLLTIICSYASIYMEIFRHSRMP-------------------
-------------NSEGFRRSSIDVLGRAKRRTLKMTITIVMAFVICWTPYYVMSVWYWL
DQKSA--EN---VDQRVQKGLFLF--ACTNSCMNPIVYGIYNVK---LRKKKKPDG----
--VK--------------SGQSSVILRNSAKYTRHSESIRS----------SSG------
----------------------------------KIRGYRDLDIPSCAIKPV--------
-----------
>gi|50978830|ref|NP_001003121.1	Canis lupus
------------------------------------------------------------
MASASPEQNQNHCSAVNNSNML-----------------MQGNLP--------------T
LTLSGKIRVTVTFFLFLLSTIFNASFLLKLQKWTQK---KEKGKKL---SRMKVLLKHLT
LANLLETLIVMPLDGMWNITVQWYAGE---FLCKVLSYLKLFSMYAPAFMMVVISLDRSL
AITRPL---A-MKNNGKLGQSMIGLAWLLSGIFAGPQLYIFRMIHL-------------A
DSSG------------QTEG-FPQCVTHCSF---------------------------PQ
WWHQAFYNFFTFSCLFIIPLFITLICNAKIIFTLTRVLHQD-------------------
----------PHEL--QLNQSKNN-IPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWF
DPEML--NR---VSDPVNHFFFLF--ALLNPCFDPLIYGYFSL-----------------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|82754178|gb|ABB89901.1|	Eublepharis macularius
---------------------------------------------MNTTFPMKVHKMVES
GLSIVDNQSHGKPNSIEEIWAD-------GTTNGSCSGEELFQLP--------------T
FSTAAKVRVAITIVLFLSSAFFNIAVL-----WTIT---QKY-HKR---PHLRILLMNLA
AADLLVTFVVMPLDAVWNITVQWYAGD---VACRLLMFLKLVAMYASAFVTVVISLDRRA
AILNPL---S-VGEAKRKNKVMLCVAWALSLLLALPQMFVFHTVSR-------------S
QPV----------------Y-FIQCATVGSF---------------------------HA
HWQEILYNMFTFCFLFLLPLLIMVVCYSRIFIEISRKMKKA-------------------
-----CAPPKSREF--HLRRSYNN-IPRARMRTLKMSVVIVLTFVVCWTPYYMLGLWYWF
SPEMLTREQ---VPPSLSHILFLF--GLFNACLDPIIYGLFAVH---FRVESKQGC-CCG
RRKK--------------EPEASSMFTSSFRASTTMPVRQP----------EDI------
----------------------------REKYKAEFTVGESPPGAKLPLYRRKMVESFI-
-----------
>gi|115969606|ref|XP_001188548.	Strongylocentrotus purpuratus
-------------------------------------MAVPTSHRDGSEPGMNAEWGKPG
GFDGADVVIIAPTMDIGFAYNY-----SLNDSLDASGNETDFEVP--------------V
FTPEYLIRVVTLTSIMVLSGPLNVAVF-----ASLW---RER-RRK---SRINLLIMHLT
LADLLITFINIPTDVIWFCTVRWLAGN---VMCKLLMFIESSAMYASSFVLIVISLDRFA
AIVHPL---S-VSKADRRCKIMLRVAWSSSVFCSIPQLFVHEVGSP-------------P
EDP----------------S-FTQCVDYNFANN------------------------RPR
LWWL--YHVFVTLAMYIVPLIAIFGCYVAIVYKICKKSREV-------------------
------TKALKNGNHPGLRRTGLDRLPRARMKALQLTATIVTAFIICWSPYYIVSTWYHF
DSGWQSEEKKMLKPEWVIDVLMAL--GYSNICVDPIIYGLFSTK---LWRQLRSCW-KKK
SLSD--------------SRSPKTMTKRTLSSSHSTVTRAT-------------------
-------------------------SVRFGVMTSVHSCPHEHPGIEMSHMTQTRVDSVSD
-----------
>gi|45552233|ref|NP_995639.1|	Drosophila melanogaster
------------------------------------------------------MAKVAE
ENDHRDLSNWSNVNDTNGTIHL---------------------------------TKDMV
FNDGHRLSITVYSILFVISTIGNSTVL-----YLLT---KRRLRGP---LRIDIMLMHLA
IADLMVTLLLMPMEIVWAWTVQWLSTD---LMCRLMSFFRVFGLYLSSYVMVCISLDRYF
AILKPL------KRSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEH-------------P
AVT----------------G-YFQCVIFNSF---------------------------RS
DFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIYRKSQRV-------------------
---------LKDVIAERFRRSNDDVLSRAKKRTLKMTITIVIVFIICWTPYYTISMWYWL
DKHSA--GK---INPLLRKALFIF--ASTNSCMNPLVYGLYNIR---GRMNNNNPS-VNN
RHTSLSNRLDSSNQLMQKQLTNNSLLNGRGQVMAAAVSATTKLANVVSLKGTANGNGSAA
AAGTVPITPPLTVTIAPLATDDEANDDSCLSAVTIRCQDQSPIRQKCGDSIELTSVVK--
-----------
>gi|18075913|emb|CAD11992.1|	Dicentrarchus labrax
---------------------------------------------MNTTLCDSAVALYHL
TTDHQLNASCNYSSPTSN-WTS---------------GGGALQLP--------------T
FTTAAKVRVIITCILCGISAFCNLAVL-----WAAH---SDG-KRK---SHVRVLIINLT
VADLLVTFIVMPVDAVWNITVQWLAGD---LACRLLMFLKLQAMYSCAFVTVVISLDRQS
AILNPL---A-INKARKRNRVMLTVAWGMSVVLSVPQLFLFHNVTI-------------I
HPE----------------D-FTQCTTRGSF---------------------------VT
HWHETAYNMFTFSCLFLLPLVIMITCYTRIFCEISKRMKKD-------------------
-------NLPSNEV--HLRRSKNN-IPRARMRTLKMGIVIVSSFIVCWTPYYLLGLWYWF
FPDDL-EGK---VSHSLTHILFIF--GLVNACLDPVIYGLFTIH---FRKGLRRYY-CNA
TKAA--------------DLDNNTVITGSFICAANSLPLKR----------EAS------
-----------------------QERFMLYSDNHSRAESTSPRSSFLRDPNQSSSESNL-
-----------
>gi|126471027|dbj|BAF48112.1|	Bufo marinus
-----------------------------------------------------------M
RFSVAGDSGKDSSLGNDIAWKG---------VGFTVPSLFPTILPNTTQMSLNSSDLLSR
DEELAKVEIAVLAIIFVAAVLGNCSVL-----LGLY---RSK-KKM---SRMHLFIKHLS
LADLVVAFFQVLPQLFWEVTYRFYGPD---FLCRVIKHLQVFGMFASAYMLVVMTADRYI
AICHPL---KTLQQPTKRSYLMISGAWILSFILSTPQYGIFYLKEL-------------G
D------------------G-VYDC--WADF---------------------------VL
KDGAKAYITWITISIFVVPVTILLTCYGFICYNIWKNIKCK-----------------TK
KEETEGRKGNNGLL--STSVSSVRTISRAKIRTVKMTFVIVSAYIICYSPFFAIQLWSVY
AEDTNWTEN---ENMAITVSALL---ASLNSCCNPWIYMFFSGH---LLQDFIISI-LCC
SKFK--------------QSTSKEDSDSSTRRQ-TSFTRMQ----------SRS------
-------------------------------PTNSMDTWKESPKSSRSIKFLAYKPDTGQ
-----------
>gi|70910044|emb|CAI64587.1|	Crassostrea gigas
------------------------------------------------------------
-----MDEHLSTNESTSLPSYL-------------------------------------K
FSDNYAHSIISLGVVFLIGALGNIASF-----VTLL---CSK-NRK---SPTNFFLLHLS
SADLLVMFVIPVGEMIHNATIAWLGGN---FLCKLYHFLWNFGQYVATFLLCCISIDRYL
AFVFPL---RSLTQSPRTRSFMAATAWVLSAILSAPESVIFHVETH-------------P
KYR----------------T-FRQCVTFNFF---------------------------PS
HNHELAYNLFNLITLYALPLLIITTSYSLILWEISKKTKQC-------------------
-----KEETKCLSTRSRLRRSSVGNMERARIRTLKMTLVIVSVFVICWTPYFVLSAWWWF
DSDSA--SQ---LDPKVQRGLFLF--AVSNSCMDPIVYGMFTTT---FRRETQKWG-RWL
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|47606680|gb|AAT36323.1|	Anopheles gambiae
-------------------------------------MYLAAGLLNIMDISLQHEYLQEY
LQSAAAMANFSGANPYGLGGFGGLAPNGTGLLGGLDKNGTEVTIT------------APG
HTDSTVAVIIVYCVLFVIAAGGNLSVV-----ITLF---RSRRHRR---SRVSLMICHLA
VADLMVAFIMIPLEVGWRITVQWHAGN---VACKVFLFMRAFCLYLSSNVLVCVSLDRCF
AVIYPL---R-VSAARKRGKIMLGGAWFIAFVNAMPQSIIFRVQQH-------------P
QVP----------------G-FTQCVTFGFF---------------------------AT
PGLETAYNLFCVIAMYFLPLMIISGAYTVILCEISNRSREK-------------------
---ETSDSNSTGTM--RLRCNDLTHIERARQRTLRLTITIVVVFVWCWTPYVVMTLWYMF
DRESA--AK---VDVAVQDGLFLM--AVSNSCMNPLVYGSYAMK---CRLPCRRRN-TLG
GAQT---------------PNAAQRRSTGFRCQQRWDPKMN----------LRF------
----------------------------------------------CMSILKNISFSLLL
LW---------
>gi|126313702|ref|XP_001369168.	Monodelphis domestica
------------------------------------------------------------
--MTTSNDTVWGSSVGEEAWAG------------AGVQVEESALP--------------T
FSTAAKIRVGVTAALFLSSAVGNLAVL-----WSVTRPRSSR-LRP---SPVRRLFGHLA
AADLLVTFVVMPLDAAWNTTVQWLAGD---VACRTLMFLKLLAMYAAAFLPVVIGLDRQA
AVLHPL---G----PRGGGRKLLGTAWGLSFLLALPQLFLFHTVRR-------------A
GPV----------------P-FIQCVTKGSF---------------------------KA
RWQEIAYNLFTFCGLFLIPLTAMAICYGRIVFSVSRHRTGK-------------------
-----GEHAPAGQF--ALRRSFDN-RPRVRLRALRLALLVLLTFVICWTPYYLLGLWYWF
SPSML--SN---VPPSLSHILFLF--GLLNAPLDPLLYGAFTLG---CKKGHQGLG----
-------------------SDSSRGRMDSWRVPQQVVQPPS-------------------
---------------------------------------QLEVNTEGNGKAGEMEETTL-
-----------
>gi|57619282|ref|NP_001009752.1	Ovis aries
------------------------------------------------------------
-MEGAFAANWSAEAVNGSAAPP------------GTEGNRTAGPP-------------QR
NEALARVEVAVLSLILFLALSGNACVL-----LALR---TTR-HKH---SRLFFFMKHLS
IADLAVAVFQVLPQLLWDITFRFYGPD---LLCRLVKYLQVVGMFASTYLLLLMSLDRCL
AICQPL---RSLR--RRTDRLAVLATWLGCLVASAPQVHIFSLREV-------------A
DGV------------------FD-C--WAVF---------------------------IQ
PWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLK-----------TEAAAAEA
AAGAEGAAADCAGRAALARVSNVKLISKAKIRTVKMTFIVVLAFIVCWTPFFFVQMWSVW
DAD---------APKEASAFIIAMLLASLNSCCNPWIYTLFTGH---LFQDLVQRFLCCS
FRRL--------------KGSQPGETSVSKKTHSYTFVLSR-------------------
---------------------------------------HSSSQRSCSQPSTV-------
-----------
>gi|35215011|dbj|BAC77240.2|	Oreochromis niloticus
---------------------------------------------MNASLCDPAAVMYQL
VADHQLNTSCNCSSGLSN-WTA---------------RGEAPQLP--------------T
FSAAAKARVIITFILCGISAFCNLAVL-----WAAR---VDG-NEN---PHVRVLIVNLT
MADLLVTFIVMPVDAVWNITVQWLAGD---FACRLLMFLKLQAMYSCAFVTVVISLDRQS
AILNPL---A-INKARKRNRIMLMVAWAMSVVLSVPQMFLFHNVTI-------------I
HPE----------------D-FTRCTTRGSF---------------------------VT
HWQGKKNNMFTFCCLFLLPLVIMITCYTRIFCEISRRLKKD-------------------
-------NLPSSEM--HLRCSKNN-IPRARMRTLKMSIVIVLSFIICWTPYYLLGLWYWF
FPGDL-EGK---VSHSLTHILFIF--GLVNACLDPLIYGLFTIH---FRKGLRRFY-TGT
TTAA--------------DLENNTVITGSFSCAANSLSL---------------------
------------------------------------------------------------
-----------
>gi|33316064|gb|AAQ04564.1|AF43	Petromyzon marinus
---------------------------------------MKCALMEPINMNMTPRAAFLN
NVTGPPNASHTGDEQLTNSSIN-----------------SDIRLP---------------
---ATQFRVISTFALFIFAAISNLTVL-----CTIS---HNHRKTK---SHVRILIVNLT
TADLLITFIVMPLDAVWHITTQWYAGE---FACRLLMFLRLLAMYSSAFITVVISLDRHS
AILNPL---G-IGKAKAKNKTMLSVAWVLSVLLAVPQLFLFHVKSP-------------K
GNK----------------N-FVQCVTHGNF---------------------------VE
QWHHNLYYMFTFVFLFILPLFIMIFCYCRILLEISKRMREG-------------------
-------SISSKEI--RLRRSNNN-IPKARMRTLKMSIAIVSSFVVCWTPYYVLGIWYWF
DRSIVSRKV---VPHFVEEMSLTF--GLLNACLDPVIYGVFAAH---VRREVRRCC-RWP
RTAAHD------------RDSSSTPVTGSFRYSASSVRSRRVPFACGEQPEATGAHPTPA
TRLLQRGCLVAGVPVNRAAAGMAAGAKAFCDASGGGAGGGGGGGEGCTEKTLVCPESCI-
-----------
>gi|30144694|gb|AAP15164.1|	Rana ridibunda
------------------------------------------MNASDQPMEDGEAALPGL
CAFKGFNLSCVHTNGFEKPHGP----------NITFLNEDHFVLP--------------T
FSTAAKIRVAITCVLFISSACFNMATL-----WTIT---YKY-RKK---SHIRILIINLV
AADLLITFVVMPLDAVWNVTIQWYAGD---VACRILMFLKLVAMYSSAFVTVVISLDRHA
AILNPL---G-IGDAKKKNKTMLSIAWTLSLLLATPQLFVFHTVSR-------------S
QPV----------------H-FVQCATLGSF---------------------------KA
HWLETLYNMFTFCCFFLLPLLIMVFCYGRILLEISRKMKKA-------------------
-----EAS--SREV--NLRRSYNN-IPRARMRTFKMSLVIVLTFIVCWTPYYLLGIWYWF
SPEMLTSRR---VPPSLSHIPFLF--GLFNTCLDPIIYGLFTIH---FRREIRRVC-RCA
TQGK--------------DADATSLGTGSFRVSTAAVPLKR----------SAG------
-------------VSGGS-----------CKFDLEVT-GVGLHSGKCEHCKRQIVESFM-
-----------
>gi|125987283|ref|XP_001357404.	Drosophila pseudoobscura
------------------------------------------------------------
--DHRILKDWSNVNNTNGTMHL---------------------------------SKDMI
FNDGHRLSITVYSILFVISTIGNSTVL-----YLLT---KRRLRGP---LRIDIMLMHLA
IADLMVTLLLMPLEIAWAWTVQWRSTD---LMCRLMSFFRVFGLYLSSFVMVCISLDRYY
AILKPL------QRSYNRGRIMLACAWMGSVICSIPQAFLFHLEEH-------------P
VVR----------------G-YFQCVTFHSF---------------------------VS
DFDNWLYQIATMCAMYAFPLIVFIYCYGAIYLEIYRKSQRV-------------------
---------LKDVIAERFRRSNDDVLSRAKKRTLKMTISIVIVFIICWTPYYTICMWYSL
DKTSV--DK---VNSLVRKALFIF--ASTNSCMNPLVYGLYNIR---GRMNNNNNV-SVN
NRHT--------------SLSNRLDSSNQLMQKPAAANNNS-------------------
----------------------------LANRHGTVMAAAVAATTKLAHVVGLKSNGSNG
SA---------
>gi|11993050|gb|AAG42574.1|AF14	Rana catesbeiana
------------------------------------------MNASDQPMGDGEAAPPGL
CAFKGFNFSCVHANGFEKPHGP----------NITFLNEDHFVLP--------------T
FSTAAKIRVAITCVLFISSACFNMATL-----WTIT---YKY-RKK---SHIRILIINLV
AADLLITFVVMPLDAVWNVTIQWYAGD---VACRILMFLKLVAMYSSAFVTVVISLDRHA
AILNPL---G-IGDAKKKNKAMLSVAWTLSLLLATPQLFVFHTVSR-------------S
QPV----------------H-FVQCATVGSF---------------------------KA
HWLETLYNMFTFCCLFLLPLLIMVFCYGRILVEISRKMKKA-------------------
-----EVS--SREV--NLRRSYNN-IPRARMRTFKMSLVIVLTFIVCWTPYYLLGIWYWF
SPEMLTSRK---VPPSLSHILFLF--GLFNTCLDPIIYGLFTIH---FRREIRRVC-RCA
TQGK--------------DADATSLGTGSFRISTAAVPLKR----------SAG------
-------------ASGGS-----------CKFDLEVT-GVGLHSGKCEHCKRQIVESFM-
-----------
>gi|108514727|gb|ABF93210.1|	Epinephelus coioides
------------------------------------------------------------
-----MSGNWSPSPNTSQFPPL-----------------TDWEAP--------------T
FTRAAQFRVGATFILFLFTACSNLALF-----ASVW-CGRGR-RLA---SHLRPLMLSLA
SADLMMTFVVMPLDAVWNVTVQWYGGD---VLCKLLCFLKLFAMHASAFILVVISLDRQH
AILHPL---D-ALNAHRRNRRMLLLAWSLSLVLASPQLFIFRTIRV-------------E
AVD------------------FTQCATHGSF---------------------------SH
RWQETVYNMFHFITLYVVPLLVMSCCYSRILLHIHLQHLRD-------------------
---------KAGES--YLRRSGTDIIPKARLKTLKMTVVIVLSFVVCWTPYYLLGIWYWF
QPDML--RV---TPEYVHHALFLF--GNLNTCCDPIIYGFYTPS---FRADLAA---CCR
RTKS--------------DASLRSPDRLSARQDPHSAEHEA-------------------
------------------------------------------DPTTNNQPAGD-------
-----------
>gi|28380055|sp|Q9TTI8|GNRHR_TR	Trichosurus vulpecula
-----------------------------------------------------------M
ANRAYLEQKQTQCSIINSSFSM-----------------THRDLP--------------T
LTLSGKIRVMVTFFLFLVSTAFNASFLMKLQRQTQK---KEEVKKL---TRMKVLLKHLT
LANLLETVIVMPLDGIWNVTVQWYAGE---FLCKALSYLKLFSMYAPAFMMVVISLDRFL
AITRPL---A-VKSNTKVGQSLIAVAWFLSIVLAGPQLYIFRMIYV-------------E
DISG------------QTGN-FSQCVTHCSF---------------------------PE
WWQEAFYNLLTFSCLFIGPLLIMLVCNAKIIFTLTQVLHQD-------------------
----------PHEL--QLNRSKNN-IPRARLRTLKMTVAFATLFTICWTPYYVLGIWYWF
DPEML--NR---VSDPVNHFFFLF--GLLNPCFDPLIYGYFSL-----------------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|110749162|ref|XP_392570.3|	Apis mellifera
------------------------------------MTILNNYTTYMLLACDNLTNFFNH
TRDLTLDSRLWNTSELSHPFHS----------YNLKNITCLEQAP--------------H
SNGNTLFKSLILTIMAVVSILANLATI-----YSIVRCR-RRHHSW---SAIYTLILQLA
VADLFVSVFCIGGEAMWNYTVEWIWGN---VACKLFKFFQVFSLYLSTFVLVLIGVDRFF
AIRYPM---K-GMNTADRCLKFIVAAWILSFVLSLPQIIIFRVVQG-------------P
FVE----------------K-FEQCVTYGFY---------------------------TE
PWQEQLYVSFGLFSMFLLPLGILIATYVFTIITISRSERMF-------------------
----KVKLANNDICHVNGDVNRRKLMYRAKAKSLRISIVIVTAFIFWWTPYYTMMIIFMF
SCPD---KH---VSDELQNIIFFF--GMSNSLVNPLIYGAFHLW---PRKRRNFMH-REI
STTQ--------------RRLTPTSYGSSYRRDSRETRIPIL---------PKN------
------------------------------------------------------------
-----------
>gi|6808613|gb|AAF28464.1|	Morone saxatilis
---------------------------------------------MNTTLCDSAVAMYHL
TTDHQLNASCNYSSPTSN-WTS---------------GGGSLQLP--------------T
FTTAAKVRVIITCILCGISAFCNLAVL-----WAAH---SDG-KRK---SHVRVLIINLT
VADLLVTFIVMPVDAVWNITVQWLAGD---LACRLLMFLKLQAMYSCAFVTVVISLDRQS
AILNPL---A-INKARKRNRVMLTVAWGMSVVLSVPQLFLFHNVTI-------------I
YPE----------------D-FTQCTTRGSF---------------------------VT
HWHETAYNMFTFSCLFLLPLIIMITCYTRIFCEISKRLKKD-------------------
-------NLPSNEV--HLRRSKNN-IPRARMRTLKMSIVIVSSFIVCWTPYYLLGLWYWF
FPDDL-EGK---VSHSLTHILFIF--GLVNACLDPVIYGLFTIH---FRKGLRRYY-CNA
TKAS--------------DLDNNTVITGSFICAANSLPLKR-------------------
-----------------EVSPASQERFVLYSDNHSRAELTSPRSSFLRDPNQSSSESNL-
-----------
>gi|6093618|sp|O62793|OPSD_MESB	Mesoplodon bidens
---------------------------------------------MNGTEGLNFYVPFSN
HTGVVRSPFEYPQYYLAEPWQF--------------------------------------
-----SVLAAYMFLLIMLGFPINFLTL-----YVTV---QHK-KLR---TPLNYILLNLA
VANLFMVLGGFTTTLYTSMHAYFIFGP---TGCNLEGFFATLGGEIALWSLVVLAIERYV
VVCKPM---SNFRFGENHAIMGLALTWIMALACAAPPLVGWSRYIP-------------E
GMQ---------------------CSCGVDYYT------------------------PSP
EVNNESFVVYMFVVHFSIPMVIIFFCYGQLVFTVKEAAAQQ-------------------
--------------------QESATTQKAEKEVTRMVVIMVVAFLICWVPYASVAFYIFT
HQG----SN---FGPIFMTIPSFF--AKSSAIYNPVIYIMMNKQ---FRNCMLTTL-CCG
RNPL--------------GDDEVSTTASKTETS-QVAPA---------------------
------------------------------------------------------------
-----------
>gi|4406502|gb|AAD20002.1|	Carassius auratus
----------------------------------------------MSGKMPL-------
-LSVNPTSIWENSSVLNATPHF----------------PSDWETP--------------T
FTVAAHFRVVATLVLFVFAAISNLSVL-----ISVT--RGRGRHLA---SHLRPLIGSLA
SADLVMTFVVMPLDAIWNITVQWYAGN---AMCKNLCFLKLFAMHSAAFILVVVSLDRHH
AILHPL---E-ALDAGRRNRRMLLAAWILSILLASPQLFIFRAIKA-------------E
GVD------------------FVQCVTHGSF---------------------------RQ
RWQETAYNMFHFVTLYVFPLLVMSFCYTHILVEINRQMPRG-------------------
-------KGKGGEP--CLRRSGTNMIPKARMKTLKMTIIIVASFVVCWTPYYLLGIWYWF
QPRML--QS---MPEYIHHALFVF--GNLNTCCDPVIYGFFTPS---FRADIASCF-CRR
NQ----------------NSSLKSLDRLSVRRGGASREAES-------------------
------------------------------------------DLGSGDQPSGQQA-----
-----------
>gi|14916996|sp|O42329|GNRR2_CL	Clarias gariepinus
----------------------------------------------MSGNTTLLLSNPTN
VLDNSSVLNVSVSPPVLK-WET----------------------P--------------T
FTTAARFRVAATLVLFVFAAASNLSVL-----LSVT-RGRGR-RLA---SHLRPLIASLA
SADLVMTFVVMPLDAVWNVTVQWYAGD---AMCKLMCFLKLFAMHSAAFILVVVSLDRHH
AILHPL---D-TLDAGRRNRRMLLTAWILSLLLASPQLFIFRAIKA-------------K
GVD------------------FVQCATHGSF---------------------------QQ
HWQETAYNMFHFVTLYVFPLLVMSLCYTRILVEINRQMHRS-------------------
-------KDKAGEP--CLRRSGTDMIPKARMKTLKMTIIIVASFVICWTPYYLLGIWYWF
QPQML--HV---IPDYVHHVFFVF--GNLNTCCDPVIYGFFTPS---FRADLSRCF-CWR
NQNA--------------SAKSLPHFSGHRREVSGEAESDL-------------------
--------------------------------------------GSGDQPSGQ-------
-----------
>gi|130487536|ref|NP_001076207.	Oryctolagus cuniculus
-----------------------------------------------------------M
ENSASPEQNQNHCSAINNSIPL-----------------MQGNLP--------------T
LTLSGKIRVTVTFFLFLLSTTFNASFLMKLQKWTQK---KEKGKKL---SRMKVLLKHLT
LANLLETLIVMPLDGMWNITVQWYGGE---ILCKVLSYLKLFSMYAPAFMMVVISLDRSL
AITRPL---A-VKSNDKLEQSMIALAWILSSVFAGPQLYIFRMIHL-------------T
NGYG------------QTEV-FSQCVTHCSF---------------------------PQ
WWQQAFYNFFTFSCLFLIPLLIMLICNVKIIFTLTRVLHQD-------------------
----------HHKL--QLNQSKNN-IPRARLRTLKMTVAFATSFIVCWTPYYVLGIWYWF
DPEML--NK---VSDPVNHFFFLF--AFLNPCFDPLIYGYFSL-----------------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|5733822|gb|AAD49750.1|AF174	Typhlonectes natans
----------------------------------------------------------MN
STFSSEDRDPTHLAAINHSWGPVEVAAETTRLNTTHHSEEVFVLP--------------T
FSTAAKVRVTITFVLFISSACFNIIAL-----WTIT---QKY-KKR---SHVRILISNLA
VADLLVTFIVMPLDAIWNITVQWYAGD---LVCRVLMFLKLVAMYASAFVTVVISLDRQS
AILNPL---G-IGDAKKKNKIMLCVAWVLSVLLAVPQLFVFHAVSP-------------S
QSE----------------Y-FIQCATVGSF---------------------------QG
HWQETLYNMFTFSCLFLLPLLIMVLCYSRILIEISRKMKKA-------------------
-----CVS--SKEV--HLRRSSNN-IPKARLRTLKMSIVIVLTFIVCWTPYYLLGIWYWF
SPEMLTRER---VPPSLSHILFLF--GLFNACLDPLIYGLFTIH---FRREIRRVC-RCR
---K--------------GVKELNIATGSFRVSTSAVPTGK----------ASG------
-------------AQNG----------------LEVT-GLNLQLGKCEQCRRKMAESFL-
-----------
>gi|76253787|ref|NP_001028995.1	Ciona intestinalis
-----------------------------MATVSSLVTTAATAMDGTTMSTPITSTFDIN
ASYHSLNATLDSNSTYFEKWCP-----------------YYHKML--------------T
FNTIQLTRVIITWILFLVSTCGNSFVL-----YCLC-----KQKQR---LHVHVITMHLT
LADLAFTFFSMPMDATWNTTMAWLGSE---FLCRLCQFLKQFGMYISSLMVVVIALDRVF
SILSPM---S-ANQQRKRTKILLISAWTLSLLCAIPALFLFSLIRKQF----------CP
DQP----------------I-FHQCVDFSRN---------------------------IN
KQDLKPYYFFTMCVSFLIPLFFTVISYSLILCEINAMQRRD-------------------
---------------ERITGRRDNNIERARMKTLVLTSLVTLSFIVLWGPYYAMGIYHWF
NPIER--AT---FPKEISVGLFVL--MYFHPAVHPILYGFFMKD---IRKHFLATLMRCF
KLSR--------------IPASRRASDKFGSCQRHLPEGNPHPRAGRAASSPLL-SPVTE
R------------TVLRATSVPFIDAVKRNQNNNRQEIFLQVPPTNGELSTQRCCDERV-
-----------
>gi|48675949|ref|NP_001001639.1	Sus scrofa
------------------------------------------------------------
--MSAGNGTPLGSAVGEEVWAG------------SGVEVESSELP--------------T
FSVAAKVRVGVTVVLFVSSAGGNLAVL-----WSVTRPQPSQ-LRP---SPVRRLFAHLA
AADLLVTFVVMPLDASWNITVQWLAGD---IACRTLMFLKLMAMYAAAFLPVVIGLDRQA
AVLHPL---G----PRSGGRKLLGAAWLLSFLLALPQLFLFHTVRR-------------A
GPV----------------P-FTQCVTKGSF---------------------------KA
QWQETTYNLFTFCCLFLLPLTVMTICYSRIVLSVSSPRTRK-------------------
-----GNDAPAGEF--TLRRSLDN-RPRVRLRALRLALLVLLTFVLCWTPYYLLGLWYWF
SPTML--SE---VPPSLSHILFLF--GLLNAPLDPLLYGAFTLG---CRRRHQELS----
------------------SDSSREGGSGRMHQQESQALRQM----------EVK------
-------------------------------------------TNAAARKAGKTKETFL-
-----------
>gi|58198432|gb|AAW65902.1|	Lepomis macrochirus
------------------------------------------------------------
-----------------------------------------------------------V
NPAAYFLLACWMFLLILLGFPINFLTL-----YVTI---EHK-KLR---TPLNYILLNLA
VADLFMVFGGFTTTMYTSMHGYFVLGR---LGCNLEGFFATLGGEIGLWSLMVLAVERWL
VVCKPI---SNFRFGENHAIMGLVVTWIGACSCAVPPLVGWSRYIP-------------E
GMQ---------------------CSCGVDYYT------------------------RAE
GFNNESFVIYMFCCHFIIPMSVVFFCYGRLLCAVQEAAAAQ-------------------
--------------------QESETTQRAQKEVTRMVIIMGIAYLICWVPYASTAWWIFT
HQG----AE---FGPVLMTVPAFF--AKAAAVYNPMIYICMNKQ---FRHCMI-------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|118764562|dbj|BAF38754.1|	Cynops pyrrhogaster
-----------------------------------------------------------M
RFSGSPATPWPSSDPLLTRWNS------SLTGAPSSPGLASSSLP-PTSPSTNSSDLLDR
NEALARVEVAVLALIFVAAVVGNSCVL-----LALQ---RSR-RKS---SRMHLFILHLS
LADLVVALFQVLPQLCWEVTYRFRGTD---ALCRVVKHLQVFGMFASAYMLVAMTADRYI
AVCHPL---KTLQQPGRRSHAMIGSAWALSLLLSTPQYAIFSMCEV-------------R
SGS----------------Q-VYDC--WAHF---------------------------IE
PWGARAYVTWIAVSIFVVPVLILATCYGFICYIIWTNIRGK-------------------
----TRPSNGGAQLLSTSAVSSVKTISRAKIRTVKMTFVIVSAYVICWAPFFTVQTWSVW
DKNFMWIDS---ENTAVTVTSLL---ASLNSCCNPWIYMFFSGH---LFQDFIHSF-ICW
RKMQ--------------HNTQKEDSDSSCRRQTSFTRINN----------RSP------
--------------------------------TNSMEAWKESPKSIRSTRFLPIQT----
-----------
>gi|56304|emb|CAA48776.1|	Rattus norvegicus
-----------------------------------------------------------M
ANNASLEQDQNHCSAINNSIPL-----------------TQGKLP--------------T
LTLSGKIRVTVTFFLFLLSTAFNASFLVKLQRWTQK---RKKGKKL---SRMKVLLKHLT
LANLLETLIVMPLDGMWNITVQWYAGE---FLCKVLSYLKLFSMYAPAFMMVVISLDRSL
AVTQPL---A-VQSKSKLERSMTSLAWILSIVFAGPQLYIFRMIYLVD----------GS
GPA----------------V-FSQCVTHCSF---------------------------PQ
WWHEAFYNFFTFSCLFIIPLLIMLICNAKIIFALTRVLHQD-------------------
----------PRKL--QLNQSKNN-IPRARLRTLKMTVAFGTSFVICWTPYYVLGIWYWF
DPEML--NR---VSEPVNHFFFLF--GFLNPCFDPLIYGYFSL-----------------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|134053892|ref|NP_001076809.	Tribolium castaneum
------------------------------------------------------------
--MNFSETLWKMKDPMSASETVQDHRNLLDWSKTSLDNATEHKLP-----------ISMR
FNEGHQLSIIVYSILMVFSAIANTTVL-----VLIV---KRRRKTP---SRINTMLMHLA
IADLLVTFLMMPLEIGWASTVSWYAGD---AMCRIMMFFRMFGLYLSSFILVCISVDRFY
AVLKPL---Y-LRALDRRDKFMLLGAWLGATLCSIPQMVVFHVESH-------------P
NIT----------------W-YQQCVTYNVF---------------------------PT
YAHELTYLLFGMVMMYALPLAVIIFSYASILLEIRRRTRNP-------------------
-------------YGDSVTRSSLAFLGKAKVRTLKMTIIIVLVFFVCWTPYYVMCIWYWL
DRESA--KN---VDQRIQKALFLF--ACTNSCMNPVVYGVFNIR---ARRTGRKVS-PRV
NTIK--------------HTSCIPTPNGDSRLPPLEISLKT----------LE-------
------------------------------------------------------------
-----------
>gi|58198482|gb|AAW65927.1|	Pomoxis nigromaculatus
------------------------------------------------------------
-----------------------------------------------------------V
NPAAYFGLACWMFLLILLGFPINFLTL-----YVTI---EHK-KLR---TPLNYILLNLA
VADLFMVFGGFTTTMYTSMHGYFVLGR---LGCNLEGFFATLGGEIGLWSLMVLAVERWL
VVCKPI---SNFRFGENHAIMGLVVTWIGACSCAVPPLVGWSRYIP-------------E
GMQ---------------------CSCGVDYYT------------------------RAE
GFNNESFVIYMFCCHFIIPMSVVFFCYGRLLCAVQEAAAAQ-------------------
--------------------QESETTQRAQKEVTRMVIIMGIAYLICWVPYASTAWWIFT
HQG----AE---FGPVLMTLPAFF--AKAAAVYNPCIYICMNKQ---FRHCMI-------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|9857657|dbj|BAB11961.1|	Anguilla japonica
----------------------------------------------MRMSENSSLLMLGS
QGTSMNSSSNSSVSPPSADWVA----------------------P--------------T
FTRAAQFRVVATLVLFLFAAFSNLAVL-----ISVA-RGRGR-RLA---SHLRPLIMSLA
VADLMMTFIVMPLDMVWNVTVQWYAGD---AMCKLLCFLKLFAMHSSAFILVVISLDRHH
AILRPL---D-SFDAKRRNKRMLLLAWSLSLLLASPQLFIFRVIKA-------------E
GVD------------------FTQCVTHGSF---------------------------QQ
RWQETVYNMFQFVTLYVVPLLVMSLCYTRILIEINHQIHKS-------------------
---------KGGES--CLRRSGTDMIPKARMKTLKMTIIIVVSFVVCWTPYYLLGIWYWF
HPQMI--QV---TPEYVNHILFVF--GNLNTCCDPVIYGLYTPS---FRADLAVCW-FCR
P-----------------QDSSPKSLDRLSARQGNPSAEQE----------SDA------
------------------------------------------PSVDQMRANEE-------
-----------
>gi|60302672|ref|NP_001012627.1	Gallus gallus
----------------------------------MARLGGGTGQDAAAAGGGWLDPGPTV
GNVSTEPSSSTSHPKRGCAWSP-----------RLESAEEPLLLP--------------T
FSPAAQARVAATFVLFVLSAGCNVAVL-----RAAG---GRRGGGR---SHIRVLLRHLA
AADLLVTVVVMPLDAIWNITLQWRAGD---LACRLLMYLRLLAMYASAFVTVVISLDRQA
AILRPL---A-IARARCRNRAMLRAAWMLSAALAVPQLFLFHTVTL-------------H
APH----------------N-FTQCTTHGSF---------------------------PQ
PWHETLYNMLSFSCLFLLPLLIMVCCYTRILLEISRRMGSS-------------------
-----LFS--SRDV--PLRCSGSN-IPRARLRTLKMSLVIVSSFILCWTPYYLLGLWYWF
CPRAM-QQK---VPPSLSHILFIF--GLFNACLDPITYGLFTIP---FR---RRCG-CPC
GHSS--------------EPEPPSPATGSFHCSASSLRGRQ----------GMG------
-------------GTEGP--------------HPPIELGLPTGAGSCQSSAL--------
-----------
>gi|37362422|gb|AAQ88392.1|	Oreochromis aureus
---------------------------------------------MNASLCDPAAVMYQL
VADHQLNTSCNCSSGLSN-WTA---------------RGEAPQLP--------------T
FSTAAKARVIITFILCGISAFCNLAVL-----WAAR---VDG-KRK---SHVRVLIVNLT
MADLLVTFIVMPVDAVWNITVQWLAGD---FACRLLMFLKLQAMYSCAFVTVVISLDRQS
AILNPL---A-INKARKRNRIMLMVAWALSVVLSVPQMFLFHNVTI-------------I
HPE----------------D-FTQCTTRGSF---------------------------VT
HWHETAYNMFTFCCLFLVPLVIMITCYTRIFCQISRRLKKD-------------------
-----NLP--SSEM--HLRCSKNN-IPRARMRTLKMSIVIVLSFIICWTPYYLLGLWYWF
FPDDL-EGK---VSHSLTHILFIF--GLVNACLDPLIYGLFTIH---FRKGLRRFY-TGT
TTAA--------------DLENNTVITGSFSCAANSLSLKR----------EVS------
-------------PASPERLLLCK-----AEWTPPRSSFLTANNDTDRKTHQSSAESIL-
-----------
>gi|3024257|sp|O42294|OPSD_ABYK	Abyssocottus korotneffi
------------------------------------------------------------
---------------------------------------YLVNPA--------------A
YAALG----AYMFLLILIGFPINFLTL-----YVTL---EHK-KLR---TPLNYILLNLA
VANLFMVLGGFTTTMYTSMHGYFVLGR---LGCNLEAFFATLGGEIALWSLVVLAIERWI
VVCKPI---SNFRFTEDHAIMGLAFTWVMALACAVPPLVGWSRYIP-------------E
GMQ---------------------CSCGVDYYT------------------------RAE
GFNNESFVIYMFIVHFLIPLSVIFFCYGRLLCAVKEAPAAQ-------------------
--------------------QESETTQRAEKEVSRMVVIMVIGFLVCWLPYASVAWWIFC
NQG----SD---FGPIFMTLPSFF--AKSAAIYNPMIYICMNKQ---FRHCMI-------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|114585265|ref|XP_001143957.	Pan troglodytes
------------------------------------------------------------
-MEGALAANWSAEAVNASAAPP------------GAEGNRTAGPP-------------RR
NEALARVEVAVLCLILFLALSGNACVL-----LALR---TTR-QKH---SRLFFFMKHLS
IADLVVAVFQVLPQLLWDITFRFYGPD---LLCRLVKYLQVVGMFASTYLLLLMSLDRCL
AICQPL---RSLR--RRTDRLAVLATWLGCLVASAPQVHIFSLREV-------------A
DGV------------------FD-C--WAVF---------------------------IQ
PWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLK-------------TAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DAN---------APKEASAFIIVMLLASLNSCCNPWIYMLFTGH---LFHELVQRFLCCS
ASYL--------------RGKRLGETSASKKSNSSSFVLSH-------------------
---------------------------------------RSSSQRSCSQPSTA-------
-----------
>gi|84095064|dbj|BAE66647.1|	Octopus vulgaris
------------------------------------------------------------
--MDYLNDSMFNNMTYNITSTP------------------LPDAP--------------R
FDNVYVSKLCVLGTVFVISFFGNTLVI-----IQIFRIRGSR-------STIQSLILNLA
IADLMVSFFNILMDIIWSATVEWLAGN---TMCKIMKYLTVFGLHLSTYITVSIALDRCF
AILSPM---S-RSKAPLRVRIMITMAWVLSAIFSIPQAVIFQEQRK-------------M
FRQ----------------GMFHQC--RDSY---------------------------NA
LWQKQLYSASSLILLFVIPLIIMVTSYLLILKTIVKTSRQF-------------------
-HDTPISPTSMSCYSVNHGQIRTHLFERARKRSSRMSAVIVAAFILCWTPYYIIFLGFAF
FQ-----------WDNSRTVIYFFTLGTSNCMLNPLIYGAFTIY---KVHRGRSGS-ANS
PSGTRLMIMVNKRGRSTTTTTNRMSGSGRRQLTTGQTITQC-------------------
----------------------------ASLTNPHQPVRPSPGINSTTSPNGKMPTKPPG
-----------
>gi|73968667|ref|XP_538263.2|	Canis familiaris
---------------------------------------------------MRIPGGPGA
PSAGNSSRWWPASGRGANASGD------------AGALADGGGPP-----------RDAR
NEELAKLEIAVLAVTFVVAVLGNSSVL-----VALH---RTP-RKT---SRMHLFIRHLS
LADLAVAFFQVLPQMCWDITYRFRGPD---GLCRVVKHLQVFGMFVSPYMLVVMTADRYI
AVCHPL---KTLQQPTRRSRLMIAAAWVLSLVLSTPQYLVFSMVEV-------------N
NVT----------------K-ANDC--WATF---------------------------IQ
PWGPRAYVTWMTAGIFVAPVVLLATCYGCICSHIWRSVRGR-----------------TA
LRAGAAAGAVPRGVLRAPGASSVKTISRAKMRTVKMTFVIVTVYIVCWAPFFILQMWSVW
DDGFVWIES---ENPAITITALL---ASLNSCCNPWIYMFFSGH---LLQDCVQSF-PCC
QNMK--------------QTFNKVDSDSVSRRQTSYTNNRS----------PTN------
----------------------------------SMGTWKDSPKTSKSVKFIPVST----
-----------
>gi|8249916|emb|CAB93351.1|	Oncorhynchus mykiss
-------------------------------MIIMYVITIRIYMFYFIYSHSFKPCLFQP
RMSGNLSLLRPPLVGVTGSMQP------ALSNMSQFPPLVDWEAP--------------T
FTRAAQFRVGATLILFLFAACSNLALL-----VSVC-RGRGR-RLA---SHLRPLIMSLA
AADLMMTFVVMPLDAIWNITVQWYGGD---ATCKMLCFLKLFAMHSSAFILVVVSLDRHH
AILHPL---D-SLNSHHRNKRMLGLAWGLSVLLALPQLFIFRAIKA-------------E
GVD------------------FTQCVTHGSF---------------------------KE
RWQETVYNMFYFVTLYVFPLLVMSFCYTHILIEINQQLHRN-------------------
---------KAGES--CLRRSGTDMIPKARMKTLKMTIIIVMSFVVCWTPYYLLGIWYWF
QPEML--QV---TPEYIHHALFVF--GNLNTCFDPVIYGFYTPS---FRADLAMCW-CYR
RRDI--------------NMSPRSLDRLSAHQGPHSGEQDS-------------------
----------------------------------------DAPGVEQTKETGGDGR----
-----------
>gi|63054892|gb|AAY28982.1|	Paralichthys olivaceus
--------------------------------------------------------MHHL
PRDRQLNSSWNGSSPHSN-WTA---------------GGDTLQLP--------------T
FTTAAKVRVTITFILCATSAFCNLAVL-----WAAH---SDG-KRK---SHVRVLIVNLT
VADLLVTFIVMPVDAVWNITVQWLAGD---LACRLLMFLKLQAMYSCAFVTVVISLDRQS
AILNPL---A-INEARKRNRVMLSVAWTMSVVLSVPQIFLFHNVTI-------------V
HPE----------------D-FTQCTTRENF---------------------------VS
HWHETAYNMFTFSCLFLLPLAIMIICYTRIFCEISKRLKSH-------------------
-----NLS--SNEV--HLRCSKNN-IPRARMRTLKMSIVIVLSFIICWTPYYLLGLWYWF
FPDDL-EGK---VSHSLTHILFIF--GLVNACLDPVIYGLFTIH---FRKGLRRYF-CRA
PPAP--------------DLDNNTVLTGSFTCTANILPLKR----------EVS------
-------------PASQEKSTMYGNNHGKEESTSQGGSFLTADIYTARDRNQSSSDSTM-
-----------
>gi|28848938|gb|AAO47727.1|	Macropus eugenii
------------------------------------------------------------
-----------------------------------------------------------R
NEAMAKVEVTVLSVILFLALTGNLCVL-----LALR---TTR-HKH---SRMFFFMKHLS
IADLVVAVFQVLPQLLWDITFHFYGPD---FLCRLVKYLQVVGMFASTYLLLLMSLDRCL
AICQPL---RSLR--RQSDHLSVLCTWLVCLVVSVPEIQIFSLREV-------------S
QGV------------------YD-C--WAVF---------------------------IQ
PWGPKAYITWITLTVYIIPVLVLSACYGLISFKIWQNLKLKTAH-------EPRAVGLWP
HLLPVRADVSNAAA--LSRVSSVKLISKAKIRTIKMTFIVVLAFIVCWTPFFFVQMWSVW
DPDA---------PKE--------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|10720170|sp|Q9YH02|OPSD_SPA	Sparus aurata
------------------------------------------------------------
-MNGTEGPFFYVPMVNTSGIVR-----------------SPYEYP----------QYYLV
NPAAYAALGAYMFLLILVGFPINFLTL-----YVTI---EHK-KLR---TPLNYILLNLA
VADLFMVFGGFTTTMYTSMHGYFVLGR---LGCNIEGFFATLGGEIALWSLVVLAIERWV
VVCKPI---SNFRFGENHAIMGLAFTWIMAMACAAPPLVGWSRYIP-------------E
GMQ---------------------CSCGIDYYT------------------------RAE
GFNNESFVIYMFICHFSIPLTIVFFCYGRLLCAVKEAAAAQ-------------------
--------------------QESETTQRAEREVTRMVIMMVIAFLVCWLPYAGVAWWIFT
HQG----SE---FGPVFMTIPAFF--AKSSSIYNPMIYICLNKQ---FRHCMITTL-CCG
KNPF--------------EEEEGASTASKTEASSVSSSSVS----------PA-------
------------------------------------------------------------
-----------
>gi|5725536|gb|AAD48094.1|AF079	Microtus ochrogaster
------------------------------------------------------------
-MEGTPAANWSFELDLGSGVSP------------GVEGNLTAGPP-------------QR
NEALARVEVAVLCLILFLALSATVRAA-----GLRT---TTR-HKH---SRLFFFMKHLS
IADLVVAVFQVLPQLLWDITFRFYGPD---LLCRLVKYLQVVGMFASTYLLLLMSLDRCL
AICQPL---RSLR--RRTDRLAVLATWLGCLVASAPQVHIFSLREV-------------A
DGV------------------FD-C--WAVF---------------------------IQ
PWGPNAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLK-------------------
------------------------------------------------------------
------------TAAAAAAA----------------------------------------
------------------EGTEGSAAGGAARGAGS-------------------------
------------------------------------------------------------
-----------
>gi|76880399|dbj|BAE45696.1|	Tetraodon nigroviridis
-------------------------------------------------MSRTSSFQPDF
TPAIPCQLTLSAAYNHSRSWSN------------LTVAGGTPLLP--------------T
FGAAARVRVAVTWTLCLLSAFCNLAVL-----RAAR---SGGAGRR---SRVRMLMVHLT
SADLLVTFIVMPVDAVWNVTVQWLAGD---LACRALMFLKLQAMYSCAFVTVVISLDRQS
AILHPL---A-ITEAGRRNKVMLAVAWVMSFALSLPQIFIFHSVTI-------------I
RPE----------------A-FTQCTTRGSF---------------------------PT
RWHETAYNMFTFSCLFLLPLVVMVTCYTRILVEISKRV-EN-------------------
-----NSS--SNQV--CLRRSRNN-IPRARMRTLKMSIVIVASFIICWTPYYLLGLWYWF
FPEDL-EGK---VSHAFTHILFIF--GLLNACLDPLIYGLFTIR---FRKGLRRLF-AGG
AEAA--------------EPENNTVLSGSFTRATSSLPLRS----------QVI------
-------------PASPE-------SHDAAPLTHTHTHSSSVNLQGCSTQKLHLCST---
-----------
>gi|62184115|gb|AAX73367.1|	Erignathus barbatus
------------------------------------------------------------
--GVVRSPFEFPQYYLAEPWQF--------------------------------------
-----SMLAAYMFMLIVLGFPINFLTL-----YVTI---QHK-KLR---TPLNYILLNLA
VADLFMVFGGFTTTLYTSLHGYFVFGP---TGCNLEGFFATLGGEIALWSLVVLAIERYV
VVCKPM---SNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIP-------------E
GMQ---------------------CSCGIDYYT------------------------LKP
EVNNESFVIYMFVVHFTIPMAVIFFCYGQLVFTVKEAAAQQ-------------------
--------------------QESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFT
HQG----SN---FGPIFMTLPAFF--AKGASIYNPVIYIMMNKQ---FRTCMITTL-CCG
KNPL--------------GDDEVSASASKT------------------------------
------------------------------------------------------------
-----------
>gi|28822121|gb|AAO50197.1|	Rana dybowskii
------------------------------------------MNASDQPMEDGEAALPGL
CAFKGFNLSCVHTNGFERPHGP----------NITFLNEDHFVLP--------------T
FSTAAKIRVAITCVLFISSACFNMATL-----WTIT---YKY-RKK---SHIRILIINLV
AADLLITFVVMPLDAVWNVTIQWYAGD---VACRILMFLKLVAMYSSAFVTVVISLDRHA
AILNPL---G-IGDAKKKNRTMLSIAWTLSLLLATPQLFVFHTVSR-------------S
HPV----------------H-LVQCATLGSF---------------------------KA
HWLETLYNMFTFCCLFLLPLLIMVFCYGRILLEISRKMKKA-------------------
-----EAS--SREV--NLRRSYNN-IPRARMRTFKMSLVIVLTFIVCWTPYYLLGIWYWF
SPEMLTSRR---VPPSLSHILFLF--GLFNTCLDPIIYGLFTIH---FRREIRRVC-RCA
TQGK--------------DADATSLGTGSFRVSTAAVPLKR----------SAG------
-------------VSGGS-----------CKFDLEVT-GVGLHSGKCEHCKRQIVESFM-
-----------
>gi|78098578|gb|ABB20590.1|	Periplaneta americana
-----------------------------------------------------------M
ALSSCSDQTLNCTAVITMATPT----------------------PSPTVLMEEYMTDDMK
FNDGHRMSIITYSILMVVSVAGNSTVL-----ITIL---KRRRTLR---YGNNYMFMHLA
IADLLVTFLMMPLEIAWNITVSWKGGD---LMCRIMLFFRTFGLFLSSFVIVCISLDRCV
AILRPMS--KKLLNVARRGKLMLTVAWILATLCSLPQAVIFHVEPH-------------P
NVT----------------W-YEQCVSFNFF---------------------------ST
KMHEFTYRVLGMVMMYGLPLIVIVISYACILGEIIRRYQLS-------------------
-------------PDDSFRRSSLVFLNRARNRTLKMAIIIFVVFFICWTPYYVMCLWYWI
DERSA--ET---VDHRVQKALFLF--ASTNSCMNPIVYGYFNFR---LGRGSGYGATGGR
VGQQLHHQNVVALSGNSTGLNSRRGSNSSSIYRNNSNQSMSWKNSLRSGRRNSR------
-------------ETEHLHPLPHRNSAQAITNVNGRDDQHQLHTNSNKTPNVLEDASNSN
SKNALTSVICR
>gi|23379651|gb|AAM76568.1|	Pongo pygmaeus
------------------------------------------------------------
-SAEAVNASAAPPGAEGNRTAG---------------------PP-------------RR
NEALARVEVAVLCLILFLALSGNACVL-----LALR---TTR-HKH---SRLFSFMKHLS
IADLVVAVFQVLPQLLWDITFRFYGPD---LLCRLVKYLQVVGMFASTYLLLLMSLDRCL
AICQPL---RSLR--RRTDRLAVLATWLGCLVASAPQVHIFSLREV-------------A
DGV------------------FD-C--WAVF---------------------------IQ
PWGPKAYITWITLAVYIVPVIVLAACYGLISFKTWQNLRLK-------------TAAAAA
AEAPEGAAAGDGGRVALGRVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWS--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|3024258|sp|O42300|OPSD_BATM	Batrachocottus multiradiatus
------------------------------------------------------------
---------------------------------------YLVSPA--------------A
YAALG----AYMFLLILIGFPVNFLTL-----YVTL---EHK-KLR---TPLNYILLNLA
VADLFMVLGGFTTTMYTSMHGYFVLGR---LGCNLEGFFATLGGEIALWSLVVLAIERWI
VVCKPI---SNFRFTEDNAIMGLAFSWVMALTCAVPPLVGWSRYIP-------------E
GMQ---------------------CSCGVDYYT------------------------RAE
GFNNESFVIYMFIVHFPIPLSVIFFCYGRLLCAVKEAAAAQ-------------------
--------------------QESETTQRAEKEVSRMVVILVIGFLVCWLPYASVAWWIFC
NQG----SD---FGPIFMTLPSFF--AKRPAIYNPMIYICMNKQ---FRHCMI-------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|112983116|ref|NP_001037049.	Bombyx mori
----------------------------------------------------MDIDEKVS
GPGGASQKNWSHLLHVNNTYDE---------------------LP-----------LEMR
FNYSHMVSMTVYSVLMVISATGNLTVL-----YQLV--RRRRAKRA---SRLDILLMHLA
VADLMVTFLMMPLEIAWAGTVQWFAGD---LMCRVMMFTRTFGLYLSSFVLICIAVDRYY
AILKPL-----NVTWEATVRRAIIVAWVCAGLASLPQSFIFHVEEH-------------P
EVK----------------G-YNQCVSYGSL---------------------------PT
EKHEFAYFLVNMILMYVIPLVSTLYCSCAALFEIIRRANTA-------------------
--------------NDKMRRSGIGLLGRARARTLKMTVTIVLVFFTCWSPYYCYCLWYWI
DKESI--KN---LDPALQKAMWLF--SCTNSCANPIVYGVFNRNRWNWRAGKFQNG-RCR
SGSG--------------RKGSRLPHGESTEISAATLSRAR----------HSN------
------------------------GSDHNGRRDSSYANQNGPQKHWNTINNNHVTNGMV-
-----------
>gi|3024299|sp|O42451|OPSD_PROJ	Procottus jettelesi
------------------------------------------------------------
---------------------------------------YLVSPA--------------A
YAALG----AYMFLLILVGFPVNFLTL-----YVTL---DHK-KLR---TPLNYILLNLA
VADLFMVLGGFTTTMYTSMHGYFVLGR---LGCNLEGFFATLGGEIALWSLVVLAIERWI
VVCKPI---SNFRFTEDHAIMGLAFSWVMALTCAVPPLVGWSRYIP-------------E
GMQ---------------------CSCGVDYYT------------------------RAE
GFNTESFVLYMFTVHFLIPLSVIFFCYGRLLCAVKEAAAAQ-------------------
--------------------QESETTQRAEKEVSRMVVLMVIGFLVCWLPYASVAWWIFC
NQG----SE---FGPIFMTLPAFF--AKTSAIYNPLIYICMNKQ---FRHCMI-------
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|148227062|ref|NP_001079211.	Xenopus laevis
------------------------------------------------MLTMSYQGIMDS
QDLCALNRSCFHLKEQEKTYGP----------NITVLNDKAFILP--------------T
FSTAAKIRVAITCVLFIFSACFNIAAL-----WTIT---YKY-KKK---SHIRILIINLV
AADLFITLVVMPLDAVWNVTLQWYAGD---LACRVLMFLKLAAMYSSAFVTVVISLDRQA
AILNPL---G-IGDAKKKNKIMLCVAWFLSYLLAIPQLFVFHTVSR-------------S
EPI----------------H-FVQCATVGSF---------------------------QA
HWQETIYNMFTFFCLFLLPLLIMVSCYTRILMEISHKMKAT-------------------
-----CVS--SKEI--DLRRSSNN-IPRARMRTLKMSLVIVLTFIVCWTPYYLLGIWYWF
SPEMLTEEK---VPPSLSHILFLF--GLLNTCLDPIIYGLFTIH---FRREIRRVC-RCA
AQGK--------------DHDTASVGTGSFRITTTPAPIKR----------TVG------
-------------VLGGS-----------GKFELEVT-GHGLHSGKCDQCQGRIVESFM-
-----------
>gi|156550065|ref|XP_001605342.	Nasonia vitripennis
------------------------------------------------------------
MDQLQGSRMQLLQDFNNHDFRD------------NMSMAVPTMPP------------SMT
FTRRTLTIIIVYCICFLVAAIGNLTVF-----LTLW---RGR-YRK---SRISLMICHLS
IADLLVAFFTIPIEIGWRLTVQWIAGN---YACKLFLFLRAFGLYLSNNILICVSLDRYF
AVLYPL---R-VNDARRRGKFMLSVAWFFSVLYAIPQSIVFHVENH-------------P
HHK----------------N-FTQCVTFGAF---------------------------PS
DLVENTYNVFCVLTMYFIPLAIICWVYLKILCEISSKSRDN---------------KPAG
SNGTLESSNSNQGSRMRLRRSDMSSIERARSRTLKMTIIIVVAFIFCWTPYITMNLWYVI
DKKSA--KE---VNEMVQESLFIM--AVGNSCANPLVYGSYAID---LKKECFRCFLPCT
TTKSNADVNLIQRSLGSKFQKPEMKSPGVSKQIVHSVCQAVHGFFKAGSGQTKS------
-----------------------------TNVCGKVLVPISPRLSVSTTSKGVVVEKLPL
HTIVS------
>gi|7981418|emb|CAB91995.1|	Serinus canaria
--------------------------------------------------------PMSN
KTGVVRSPFEYPQYYLAEPWKY--------------------------------------
-----RLVCCYIFFLISTGFPINFLTL-----LVTF---KHK-KLR---QPLNYILVNLA
VADLCMACFGFTVTFYTAWNGYFVFGP---VGCAVEGFFATLGGQVALWSLVVLAIERYI
VICKPM---GNFRFSASHAMMGIAFTWVMAISCAAPPLFGWSRYIP-------------E
GMQ---------------------CSCGPDYYT------------------------HNP
DFHNESYVLYMFVIHSIIPVVIIFFSYGRLVCKVPEAAAQQ-------------------
--------------------QESATTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFT
NKG----AD---FTATLMAVPAFF--SKSSSLYNPIIYVLMNKQ---FRNCMITTI----
------------------------------------------------------------
------------------------------------------------------------
-----------
>gi|149728459|ref|XP_001491715.	Equus caballus
MAGAGGAPERRWGASLSWFLEARLVLRETWKRLSISRNRRSGSFPLISSGSEGGGTAPAA
VIEGALAANWSAEAANGNAAPP------------GAEGNRTAGPP-------------QR
NEALARVEVAVLCLILFLALSGNACVL-----LALR---TTR-HKH---SRLFFFMKHLS
IADLVVAVFQVLPQLLWDITFRFYGPD---LLCRLVKYLQVVGMFASTYLLLLMSLDRCL
AICQPL---RVLR--RRVDRLAVLATWLGCLVASAPQVHIFSLREV-------------A
EGV------------------FD-C--WAVF---------------------------IQ
PWGPKAYVTWITLSVYIVPVIVLAACYGLISFKIWQNLRLK--------------TAAAA
AEGPEGASAGSGGHAAMARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DPN---------APKEASAFIIAMLLASLNSCCNPWIYMLFTGH---LFHELVQRFLCCS
SGYL--------------KGSRPGETSASKKSNSSTFVLSG-------------------
---------------------------------------HSSSQKSCLQPATV-------
-----------
>gi|119617521|gb|EAW97115.1|	Homo sapiens
------------------------------------------------MDSMRLSAGPDA
GPSGNSSPWWPLATGAGNTSRE------------AEALGEGNGPP-----------RDVR
NEELAKLEIAVLAVTFAVAVLGNSSVL-----LALH---RTP-RKT---SRMHLFIRHLS
LADLAVAFFQVLPQMCWDITYRFRGPD---WLCRVVKHLQVFGMFASAYMLVVMTADRYI
AVCHPL---KTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEV-------------N
NVT----------------K-ARDC--WATF---------------------------IQ
PWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGK-------------TASRQS
KGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVW
DPMSVWTES---ENPTITITALL---GSLNSCCNPWIYMFFSGH---LLQDCVQSF-PCC
QNMK--------------EKFNKEDTDSMSRRQTFYSNNRS-------------------
-------------------------------PTNSTGMWKDSPKSSKSIKFIPVST----
-----------
>gi|83033264|gb|ABB97085.1|	Micropogonias undulatus
---------------------------------------------MNTTLCDSEATMYHL
MTDHQLNASCNYSSPTSN-WTA---------------GGGALQLP--------------T
FTTAAKVRVIITCILCGISAFCNLAVL-----WAAH---IDG-KRK---SHVRVLIINLT
VADLLVTFIVMPVDAVWNITVQWLAGD---FACRLLMFLKLQAMYSCAFVTVVISLDRQY
AILNPL---A-INKARKRNRVMLTVAWGMSIALSVPQIFLFHNVTI-------------I
HPE----------------D-FTQCTTRGSF---------------------------VT
HWHETAYNMFTFSCLFLLPLIIMITCYTRIFCEIPKRLNKD-------------------
-----NLP--SNEI--HLRRSKNN-IPRARMRTLKMSIVIVSSFIICWTPYYLLGLWYWF
FPDDL-EGK---VSHSLTHILFIF--GLVNACLDPVIYGLFTIH---FRKGLRRYY-CNA
TTVS--------------DLDNNTVITGSFSCTANSLPLKR----------HVS------
-------------PASQEMFILCSDN---CKSASPRSSFLTADIGAETDPNQSSSESII-
-----------
>gi|147901685|ref|NP_001091663.	Danio rerio
---------------------------------------------MNDSSPTSENIMFHQ
LTADTLNGSCDLPTCNNNTGEA------------------ALQLP--------------T
FSMAAKVRVIITFTLCAVSAVCNLGVL-----WAAS---TNN-KRK---SHVRILIMNLT
VADLLVTFIVMPVDAAWNITVQWLAGD---LACRLLMFLKLVAMYSCAFVTVVISLDRQS
AILNPL---A-INKAKKKNKIMLSVAWAMSVVLSVPQMFLFHNVTI-------------T
VPA----------------N-FTQCTTRGSF---------------------------VK
HWQETIYNMFTFICLFLIPLAIMICCYTRILVEISRRMTKG-------------------
-----NIS--SKEV--HLRRSHSN-IPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWF
LPEDL-EET---VSHSLTHMLFIF--GLFNAILDPITYGLFTIH---FRKGLKRYC-RSA
VVLT--------------ESENNSIITGSLKCSPSPFRMKR----------VTQ------
-------------SGTG---------------TDPKQNTSTVGEEDKKAADGKTKE----
-----------
