>gi|110749846|ref|XP_001122092.	Apis mellifera
------------------------------------------------------------
---------------------------------MGKTFCQSCKKKCSGEVLRVQ-DKYFH
IGCFKCAQCNASLAQGGFFAR-EGSYYCTKDYRERWGTKCAGCGEYVEGDVVTAGDKHAF
HPNCFHCQRCRQPLLGQGTKVSLVQGQALCHRCVGIPVR----------------EASTP
IGNSSA-------------TRGSGDGPSDPGACAGCGNQLREGQALVALDRQWHVWCLKC
HSCDTVLHGEYMGKDGVPYCEKDYQKLFGVKCAYCNRYIS-GKVLQ--------------
---------------------------------------------AGDNHHFHPTCARCT
KCGDPFGDGEEMYLQG-AAIWHPRC-----------GPGPSGPNGIV-------------
-----------------NGHGEA-----------HTPQHRESERISSSASEMQFSLRSRT
PSLNGSLCSPYSSL---SRKYY--PAR--TGSPGLILREYGRG----------------P
SEDVSRIYTYSY---LTETPTQGYLR-RPIQPYDKP---PTSP--------HFHRPSS--
SRSIRSSGGRSS--------------------------------RSGMRALVDALSET--
------------------RPKSPASQV------------DNDEPIELAHYPDAMKPPPGT
KPPIERDDFPAPPYPYTDPERRRRWSDTYKGVPASDDEDE------VDNKTYIKEVEEKL
KKEQDELSKI--DTGIAKVFLQDREKDRENLRHRAANVDP--RNASRTPSAAREPTYRLR
YESPVGA----SPSRNID--HARPWEDDDGFSYRSSVGPSYNVVSSLRHIPKPGYGLAPR
SHTFSSTGGSGDYSFSGMGDKTHSTDFSSGKSDISTGSITDVDRRALNDGGMLPSSTTYT
GGLGSVVGSHGGHHVRRSLPDMGTAPSEPPKLYP---YHLLVI----TN---YRLPADVD
RCNL-ERHLSDAEFEA---VLQCTRAEFYR--LPQWRRNEIKRRARLF---
>gi|119917801|ref|XP_883296.2|	Bos taurus
MPCFLGLKSLGKLCNSGKGKATSSAKTSTRGSCKRRLVVQDVSFPRSPAPARRRATITHL
LYLHPDVCCTRARICNSLDPLLAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQ-TKHFH
IKCFTCKVCGCDLAQGGFFIK-NGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGK-TY
HPNCFACTICKRP-FPPGDRVTFNGRDCLCQLCAQP-------------------MSSSP
KE-ASC-----------------------SGNCAGCGRDIKNGQALLALEKQWHLGCFKC
KSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFIT-GKVLE--------------
---------------------------------------------AG-DKHYHPSCARCS
RCNQMFTEGEEMYLQG-STVWHPDC-----------KQSTKTEEKLR-------------
---------------PTRTSSESIYSRPGS-SIPGSPGHTIYAKVDNEILD--YKDLAAI
PKVKAIYDIERPDL--ITYEPF--YSS--GYDDKQERQSLGES-PRTLSPT----PSAEG
YQDGRDRM-------IHRSTSQGSIN-SPV--YSRHSYTPTTS----RSPQHFHRPGN--
EPSSGRNSPLPY--------------------------------RPDSRPLTPTYAQAPK
HFHVP---DQGI--NIYRKPPIYKQHA-----ALAAQSKSSEDIIKFSKFPAAQAPDPSE
IPKIETDHWPGPPSLAAVGADTRRRSSG-----REEEDEE---------------LLRRR
QLQEEQLMKL--NSGLGQLILKE----EMEKERESR---------------ERASLAASR
YDSPINS-------------------ASHVLSSKTASLPGY------------------G
RNGLHRPLS---------------LLMAHGGMFGELQ------------SDVISVYTLPD
GHMPGMRMDRG----------VSMPNMLEPKIFP---YEMLMV----TNRGRNKILRDVD
RTRL-ERHLAPEVFRE---IFGMSIQEFDK--LPLWRRNDMKKKAKLF---
>gi|118405054|ref|NP_001072900.	Xenopus tropicalis
------------------------------------------------------------
--------------------------------MRLMLLC---------------------
--------CSW-----------SEEH----------------------------MGE---
------------------------------------------------------------
EE-GNG-----------------------LPVCASCGQSIYDGCYLQALALDWHSDCFRC
SDCGVSLSHRYYEKDGRLFCKKHYWARFGGMCQGCSENITKGLVMV--------------
---------------------------------------------AG-EHKYHPECFMCS
RCKAYIGDVETYALVERSKLYCGPCYYQFSVTPVIDSPGSRSPHTVTL------------
-------------VSLPASDGKRGLSVSITPSCAEHSHTVRVSQLDTDCLS--PDIQSTI
HIGDRILEINGTPIRSVPLDEI--DVL--IQETSRLLQLTIEHDPHETPTL----PSPCT
EITVRRQRPIMRSCSIDRSPGSSCVG-SPS--CSRRDMSRSESVRTVTGVHRIFRPSDLM
PGEVLGRGCFGQ--------------------------------AIKVTHRVTGEVMVMK
ELIRF---DEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIPGGTLRRVI
KSMDAHYPWNQRVSFARDIAAGMTYLHSMNIIHRDLNSHN------------------CL
VREDGSLVVA--DFGLARLVTDETRDLRKDRRKRYTVVGNPYWMAP-------EMINGRS
YDESVDV--------------FSCGIVICEIIGRVNADPDY------------------L
PRTMDFGLN---------------VRAFLDRFCPPNC-----------------------
----------------------------PPGFFP---SAVLCC----DLDPEKRPRFSQL
QLWL-DSLLRHLNLQL---PLSSHLEQLERNFWENYRRGDSTLHVHPEIPE
>gi|149689656|ref|XP_001495259.	Equus caballus
MPSFLGLKCLGKLCSSEKSKVTSSERSSTRGSSRRGLVVKDVSVTGPPYPAHRRATITHM
LYLHPEVYCTFEHLCNNCDPLVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQ-TKHFH
IKCFTCKVCGCDLAQGGFFIK-NGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGK-TY
HPNCFACTICKRP-FPPGDRVTFNGRDCLCQLCAQP-------------------MSSSP
QE-ASC-----------------------SSNCAGCGRDIKNGQALLALEKQWHLGCFKC
KSCGKVLTGEYISKDGAPYCEKDYQGLFGVRCEACHQFIT-GKVLE--------------
---------------------------------------------AG-DKHYHPSCARCS
RCNQMFTEGEEMYLQG-STVWHPDC-----------KQSTKTEEKLR-------------
---------------PTRTSSESIYSRPGS-SIPGSPGHTIYAKVDNEILD--YKDLAAI
PKVKAIYDIERPDL--ITYEHF--YSS--GYDDKQDRQSLGES-PRTLSPT----PSAEG
YQDVRDRM-------IHRSTSQGSIN-SPG--YSRHSYTPTTS----RSPQHFHRPGN--
EPCSGRNSPLPY--------------------------------RPDSRPLTPTYAQAPK
HFHVP---DQGI--NIYRKPPIYKQHA-----ALAAQSRSSEDIIKFSKFPAAQAPDPSE
TPKIETDHWPGPPSLAAVGADMRRRSSG-----REEDDEE---------------LLRRR
QLQEEQLMKL--NSGLGQLILKE----EMEKESR-----------------ERSSLSASR
YDSPINS-------------------ASRALSSKTSSLPGY------------------G
RNGLHRPVS---------------TDFAQYNSYGDVS------------GGVRDYQTLPD
GHMPAMRMDRG----------VSMPNMLEPKIFP---YEMLMV----TNRGRNKILRDVD
RTRL-ERHLAPEVFRE---IFGMSIQEFDK--LPLWRRNDLKKKAKLF---
>gi|156538545|ref|XP_001607378.	Nasonia vitripennis
------------------------------------------------------------
MKSKKQSESLIASERNGLKSEPKESEQQQKSQKKGKTFCQACKKKCSGEVLRVQ-DKYFH
IGCFKCAQCNTSLAQGGFFAR-EGAYYCTKDYRERWGTKCAGCGEYVEGDVVTAGEKHAF
HPNCFHCQRCRQPLLGQGTKVTLVQGQALCHRCVSIPVR----------------EASTP
VS-SAG------------KDTGSGGTGQDPGACAGCRQELREGQALVALDRQWHVWCFKC
HSCDTVLHGEYMGKDGVPYCEKDYQKQFGVKCAYCNRYIS-GKVLQ--------------
---------------------------------------------AGENHHFHPTCARCT
KCGDPFGDGEEMFLQG-AAIWHPRC-----------GPGPTGPNGIV-------------
-----------------NGHSEAHTPQHRSTSTAGANTQDHSERISSSASE---------
-------------M---QYYPA----R--TGSPGLILREYGRG----------------G
HENVSRIYTYSY---LTETPSQGYLR-RPIQPYDKP---PTSP--------HFHRPSS--
SRSIRSSGGRSS--------------------------------RSGMRALVDALSETRP
KS------------------------------PAAGSQVDNDEPIELAHYPDASKPPPGK
QPPIERDDFPAPPYPYTDPERRRRWSDTYKGVPDSEDEDE-------VDQKSIKEVEQKL
KKEQDELSKI--DTGIAKVFLQDREKDRENLRHKAANVDP--RNASRTPSANREPAYRLR
YESPVGA----SPSRNID--HARPWEDEDGISYRSSNDGGI------------------L
PSSTTYTGGL--------------GSVAVGQHHQHVG------------QHVRRS-----
------------------LPDMGAAPAEPPKLYP---YHLLVI----TN---YRLPADVD
RCNL-ERHLSDAEFEA---VLHCTRSEFYR--MPQWRRNDIKRRARLF---
>gi|47219283|emb|CAG11745.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------VQYQSSLYGGNNNSASPPIMCERCGQLCRGEVVRVK-NTHFH
LQCFTCQVCGCNLVRSGFFHH-SGEYICTDDYQRLYGTQCDSCHQYITGEVVSALGR-TY
HPRCFVCSVCRSP-FPIGDRVTFCGKKCVCQQCSHTL------------------STDKP
VK-VHG-----------------------PSYCAGCGEEIKQGQSLLALERQWHLTCFKC
QTCGRVLTGEYISKDGAPYCEADYHTQFGIRCDSCSSYIS-GRVLE--------------
---------------------------------------------AG-GKRYHPSCARCA
RCNSVFREGEEMYLTG-SDIWHPTC-----------KEAARLERKLG-------------
---------------LRRGSETASLSPPGCSPLHGSPHRLRCSKAVSELSG--SKQLMPL
SGVRALYGTQQPDL--IPHQADRARAC--VLEDTLERHSCGQCCVMSAPLH----PSFQD
LLDGLELR-------TRNSSSSIFTDSSPA--HSRHGGSPLHSHVPGKTPTQAHFLGN--
E--AKRPGCTHS--------------------------------QILPNASSPSL-----
--------AASEETSVYGKPAAYKRRD-VSASPNTNKMKVNDNLIHSGCFSNC---NGFY
HH--DTNYYPCTGSPKV--PRVRRFSSG-----GEEDG----------------------
-----WNHNL--NRGIGRMILKE----EMRARWGCHDNDP--WGSGCSSRCGSKGALNSL
GFGSTNG----AS-------RFFRGPDSDSYVAKSSSLPGY------------------G
RNGIKRPGSLG-------------ADYYQYDSTNAVN------------WQIREY-----
------------------------------KIYP---YEALVV----SVRGQQRPPGDVD
RARL-ERHLSPEEFYR---VFGMSMSSFDH--LAQWKKNELKKQVRLF---
>gi|109090631|ref|XP_001093065.	Macaca mulatta
------------------------------------------------------------
----------------MVKEKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQ-TKHFH
IKCFTCKVCGCDLAQGGFFIK-NGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGK-TY
HPNCFACTICKRP-FPPGDRVTFNGRDCLCQLCAQP-------------------MSSSP
KE-TTF-----------------------SSNCAGCGRDIKNGQALLALDKQWHLGCFKC
KSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFIT-GKVLE--------------
---------------------------------------------AG-DKHYHPSCARCS
RCNQMFTEGEEMYLQG-STVWHPDC-----------KQSTKTEEKLRLPNIRRSSSDFFY
PKSLIRRTGRSPSLQPTRTSSESIYSRPGS-SIPGSPGHTIYAKVDNEILD--YKDLAAI
PKVKAIYDIERPDL--ITYEPF--YTS--GYDDKQERQSLGENLPRTLSESTCLSPRADG
YQDVRDRM-------IHRSTSQGSIS-SPV--YSRHSYTPTTS----RSPQHFHRPGN--
EPSSGRNSPLPY--------------------------------RPDSRPLTPTYAQAPK
HFHVP---DQGI--NIYRKPPIYKQHA-----ALAAQSKSSEEIIKFSKFPAAQAPDPSE
TPKIETDHWPGPPSFAAVGPDMRRRSSG-----REEDDEE---------------LLRRR
QLQEEQLMKL--NSGLGQLILKE----EMEKESR-----------------ERSSLLASR
YDSPINS-------------------ASYIPSSKTASLPGY------------------G
RNGLHRPVS---------------TDFAQYNSYGDVS------------GGVRDYQTLPD
GHMPAMRMDRG----------VSMPNMLEPKIFP---YEMLMV----TNRGRNKILREVD
RTRL-ERHLAPEVFRE---IFGMSIQEFDK--LPLWRRNDMKKKAKLF---
>gi|24645465|ref|NP_731390.1|	Drosophila melanogaster
----------------------------------------------------MYILIYIS
IPKHPQTDKTRPIYPSTLGTELRTELGKTGQ-GKQKIYCAKCTKKCSGEVLRVA-DNHFH
KACFQCCQCKKSLATGGFFTK-DNAYYCIPDYQRLYGTKCANCQQYVEGEVVSTMGK-TY
HQKCFTCSKCKQP-FKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATGGGVSSPAPPAESP
TR-ATA----HQQHGSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSCFRC
KACQAVLNGEYMGKDAVPYCEKCYQKGFGVKCAYCSRFIS-GKVLQ--------------
---------------------------------------------AGDNHHFHPTCARCT
KCGDPFGDGEEMYLQG-SAIWHPRC-----------GPGPSESGIIL-------------
------------------NGGGGTSSVVGG-ASNGNFTDTECDRMSSSALSEMYIRSRTP
SFNGSLYSSSRK------------HYR--TVSPGLILREYGRP----------------N
AEDISRIYTY-----SYLTDAPHYLR-KPIDPYDKT---PLSP--------HFHRPSSYA
TTASNAGSVAGS--------------------------------RPPSRPHSRTRSA---
--------MKVLVDAIRSETPRPKSPG-----------MNNEEPIELSHYPAAKKPPPGE
QPKIERDDFPAPPYPYTDPERRRRYSDTYKGVPASDDEDENVENGKPNGKVKNGEEQQRL
QREAEQLEKL--NSGIGSAIAKDLKEHAKYRKWKQNNLDP--RNASRTPSASKEPLYKLR
YESPIGA----SPSRNLDHQKPFY---EDEMFDRSTSYRGS------------------L
GKSLGNAPSY--------------NAIHSYRSPPKPG------------YGFKTTTLPYI
RNGFSSDFSYG---------------GLGDKTHS---TDLSCG----KSEASVDSITEGD
RRALMGGDLPASSTYSGALSYHYPQAGLIRRSLPNMSHSIISCANAKL---
>gi|149624304|ref|XP_001512429.	Ornithorhynchus anatinus
-------------------------------------------MASAVSGPSRVFAGRVF
LFEIRETPVSEAILAYLSAPYQQNLYNPGS--GSPAIQCYRCGDTCKGEVVRVQ-NNHFH
IRCFTCQVCGCDLAQSGFFFK-NREYICTQDYQQLYGTRCDSCRDFITGEVISALGR-TY
HPKCFVCTVCRQP-FPIGDKVTFRGKECVCQTCSLSL------------------VSAKP
VK-VHG-----------------------PSHCAGCSEEIKHGQSLLALDKQWHVSCFKC
QTCGVILTGEYISKDGVPYCEADYHAQFGIKCETCSRYIS-GRVLE--------------
---------------------------------------------AG-GKHYHPGCARCV
RCQQMFTEGEEMYLTG-SEVWHPTC-----------KQAARAEKKLK-------------
----------------LRRMSETSISPPGS-SI-GSPNRVICAKVDHEILN--YRDLAAL
PKVKALYEVQHPDL--SSYEPY--PRY--TSDEMLARWSCGES-LGTLSPY----SQVMG
IFRPVCVY-------GEESSELGCLT-NPS--YSRPTLPPCRP-----APLLVRAAGS--
E--SGRSSPFHS--------------------------------QLDVRSPTPTAYQAPK
HFHIP---AAGE-SSIYRRPPIYKRHGT--RSPAATKSKTSEDIRQASEFLPAGSPDPYC
HS--ESDFWTHHGSPKV--PRARRFSAG-----GEEDD----------------------
--YDRSLHKI--QSGIGRLILKE----EMKARSHSY-ADP--WTPPRSSTSSREALYPTS
YEASLNG----SP-------RSHYLADSDPFISKSASLPAY------------------R
RNGXFQAPS---------------SELFHYDSMNAVN------------WGMR-------
------------------------------------------------------------
---------------------------------------------------
>gi|73998611|ref|XP_864887.1|	Canis familiaris
MPSFLGLKCLGKLCSSEKSGVPSSERASTTGSYRRRLVVEDVSITGIPQPAHRRATMTHL
VYLHPEAYCTLEHLLSHLEPPVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQ-TRHFH
IKCFTCKVCGCDLAQGGFFIK-NGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGK-TY
HPNCFACTICKRP-FPPGDRVTFNGRDCLCQLCAQP-------------------MSSSP
KE-ASC-----------------------SSNCAGCGRDIKNGQALLALEKQWHLGCFKC
KSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFIT-GKVLE--------------
---------------------------------------------AG-DKHYHPSCARCS
RCNQMFTEGEEMYLQG-STVWHPDC-----------KQSTKTEEKLR-------------
---------------PTRTSSESIYSRPGS-SIPGSPGHTIYAKVDNEILD--YKDLAAI
PKVKAIYDIERPDL--ITYEPF--YTS--GYDDKQERQSLGES-PRTLSPT----PSAEG
YQDSRDRV-------IHRSTSQGSIS-SPV--YSRHSYTPTTS----RSPQHFHRPGN--
EPSSGRNSPLPY--------------------------------RPDSRPLTPTYAQAPK
HFHVP---DQGI--NIYRKPPIYKQHA-----ALAAQSKSSEDIIKFSKFPAAQAPDPSE
IPKIETDHWPGPPSLAAVGADMRRRSSG-----REEDEEE---------------LLRRR
QLQEEQLMKL--NSGLGQLILKE----EMEKESR-----------------ERSSLSASR
YDSPINS-------------------AAHVLSSKTSSLPGY------------------G
KNGLHRPVS---------------TDFAQYNSYGDVS------------GGVRDYQTLPD
GHMSGARMDRG----------VSMPNMLEPKIFP---YEMLMV----TNRGRNKILRDVD
RTRL-ERHLAPEVFRE---IFGMSIQEFDK--LPLWRRNDMKKKAKLF---
>gi|148705550|gb|EDL37497.1|	Mus musculus
----------------------------VALRAAGTVCAEPLASSVLRILPAPHLPARSS
GCRSAGTTLLGAAADMSAVSQPQAAHAPLEKPASTAILCNTCGNVCKGEVLRVQ-NKYFH
IRCFVCKACGCDLAEGGFFVR-QGEHICTRDYQRLYGTRCFSCDRFIEGEVVSALGK-TY
HPDCFVCAVCRLP-FPPGDRVTFNGKECMCQKCSPPTL-----------------LGNSA
HV-AQG-----------------------LRSCGGCGLEIKNGQALVALDKHWHLGCFKC
KTCGKLLNAEYISKDGLPYCEADYHSKFGIRCDGCEKYIT-GRVLEVRATITTKLIRAIN
TDAISTMVLEVSPMTKIVIVTQAICTATARVSRTTWAHMKPWPSQAG-EKHYHPSCALCV
RCGQMFSEGEEMYLQG-SSIWHPAC-----------RQAARTEDKSK-------------
---------------ETRTSSESIVSVPAS-STSGSPSRVIYAKLGDEILD--YRDLAAL
PKNKAIYNIDRPDM--ISYSPY----I--SHSAVGDRQSYGE-----------------G
DQDDRSYK-------QCRTSSPSSAG-S----VSLGHYTPTS-----RSPQHYSRPAG--
TVSVGTSSCLSL-------------------------------------SQHPSPTSVFR
HHYIPYFRDTGVKDNIYRKPPIYKQHA---------------------------------
---------------------ARRLD-------VEDSS----------------------
--FDQDSRKK-----TTWLLLKG----DADTRTNSPDLDS--QSLSLSSGTDQEPLQRMA
GDSLYSR----------------------FPYSKPDTLPGP------------------R
KDGLDLRN----------------ANLAPCGADPDAS------------WGTRGTHNNPV
VSFL--------------------------QIYP---YDSLIV----TNRIRVKLPKDVD
RTRL-ERHLSPEEFQE---VFGMSIEEFDR--LALWKRNDLKKKALLF---
>gi|51173711|ref|NP_002304.3|	Homo sapiens
MPAFLGLKCLGKLCSSEKSKVTSSERTSARGSNRKRLIVEDRRVSGTSFTAHRRATITHL
LYLCPKDYCPRGRVCNSVDPFVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQ-TKHFH
IKCFTCKVCGCDLAQGGFFIK-NGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGK-TY
HPNCFACTICKRP-FPPGDRVTFNGRDCLCQLCAQP-------------------MSSSP
KE-TTF-----------------------SSNCAGCGRDIKNGQALLALDKQWHLGCFKC
KSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFIT-GKVLE--------------
---------------------------------------------AG-DKHYHPSCARCS
RCNQMFTEGEEMYLQG-STVWHPDC-----------KQSTKTEEKLR-------------
---------------PTRTSSESIYSRPGS-SIPGSPGHTIYAKVDNEILD--YKDLAAI
PKVKAIYDIERPDL--ITYEPF--YTS--GYDDKQERQSLGES-PRTLSPT----PSAEG
YQDVRDRM-------IHRSTSQGSIN-SPV--YSRHSYTPTTS----RSPQHFHRPGN--
EPSSGRNSPLPY--------------------------------RPDSRPLTPTYAQAPK
HFHVP---DQGI--NIYRKPPIYKQHA-----ALAAQSKSSEDIIKFSKFPAAQAPDPSE
TPKIETDHWPGPPSFAVVGPDMKRRSSG-----REEDDEE---------------LLRRR
QLQEEQLMKL--NSGLGQLILKE----EMEKESR-----------------ERSSLLASR
YDSPINS-------------------ASHIPSSKTASLPGY------------------G
RNGLHRPVS---------------TDFAQYNSYGDVS------------GGVRDYQTLPD
GHMPAMRMDRG----------VSMPNMLEPKIFP---YEMLMV----TNRGRNKILREVD
RTRL-ERHLAPEVFRE---IFGMSIQEFDR--LPLWRRNDMKKKAKLF---
>gi|115630526|ref|XP_784724.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------CAQCNDDITQGQALVALDKHWHVWCFKC
HKCKKVLTGEYMGRDGQPFCERDFHQLFGVRCSRCDNFIT-GKVLE--------------
---------------------------------------------AG-DHKYHPTCAKCG
RCGNHFNEGEDMFVQG-TEIWHPDC-----------RKGR--------------------
-------------------------------ALGFFPSRIRENAI---LFD--YN-----
-RGKSQSTPASPVL----------ARG--HFHTPSFLSSPSRRSSNSLSPQ----SPDYS
YTYLSPFS-------ISNTIYPKPVAISPE--A------PVSP--------HFHRPE---
YVNNGEDFSYMS------------------------------PPRYDLPPPRPGGYKRRP
RPHSA---FDAL------KPKIKPVKD----------EALSAEMVRQSKFPAAKKPSASQ
PAKIESEIWPGPPAFAKYQFHSSRSKSMGDLHNSDEEEEK--------------------
-QIDAEVSKV--DSALGKEILKA----ELKQRKISN-LDP--RSASRTPAANKELPVSPR
HESSMDAENMMTPPRSSTLPPNLRYESLSEAYRKASSLPMN------------------A
RSGSWYSDAN--------------SEGYISNGYASSG------------ELSPRLANMND
RQLRTLRITTG-----------QSMPSMEPKVPKSSTKAVRIAAPKYKSTPKGRPGPVGR
RSKV-QYHLSNEDFFR---AFGMTFEDFHA--LSPWKRTVVKKNALLF---
>gi|157118566|ref|XP_001653201.	Aedes aegypti
------------------------------------------------------------
--------------------------------GKTKIQCSKCQKKCSGEVLRVS-DRYFH
KTCFQCTKCNKSLATGGFFSK-DGAYYCTLDYQKLYGTKCAACNQYVEGEVVSTMGN-TY
HQKCFTCSKCKQA-FQSGSKVTNTGKEVLCESCVKGPVAATAQTTNSEQKTIKE-ITSSP
TK-AAT-----LQHHQEAIRKQQNSKDVDPNECAGCHQQLKEGQALIALDRQWHIWCF-C
NACGVTLNGEYMGKDGVPYCEKDFQKSFGVKCAYCNRYIS-GKVLQ--------------
---------------------------------------------AGDNHHFHPTCARCT
KCGDPFGDGEEMYLQG-GAIWHPRC-----------GPGPSSESGIL-------------
---------------------------NGV-ETNGFNTETEFDRTSTSAMS---------
-EIQFSYPSQTPNLSGSVYSPYTHRKYHRTTSPGLILREYNRH----------------G
YEDIARIYTY-----SYLTDEPHYLR-KPIEPYDKA---PVSP--------HFHRPN---
QYGSGHRSASGS--------------------------------RSHSRSRSAMKVLV--
-------------DSIRSETPRPKSPG-----------MNNEEPIELSHYPGAKKPPPGE
KPKIERDDFPAPPYPYTDPERRRRYSDSYKHIESDDEVDH-----AKNKEDKENIAEMRL
QKEEEELSKLK-SSGMGKVILKDLQEHKKYEHWKRENLDP--RNASRTPSASKEPTYRLR
YESPVGA----SPSRN----LDHHRPNEDEYFDRSTSYRGS------------------V
GRAIGNAPSY--------------NAIHSYRSPPKPG------------YGFKTSTLPPS
SLRNGYSSDFS-------------FGGLGDKTHS---TEFSCG----KSDISVDSITEGD
RRAL-GADIPASSTYSGALSYHYPQQPIRRS-LPNMAHSMLVHEPAKI---
>gi|118786449|ref|XP_315432.3|	Anopheles gambiae
------------------------------------------------------------
--------SKYIFTNSRTLPLTTHSFAPSSFAGKSKIQCSKCQKKCSGEVLRVS-DRYFH
KTCFQCTKCNKSLATGGFFSK-DGAYYCTLDYQKLYGTKCAACSQYVEGEVVSTMGN-TY
HQKCFTCSKCKQP-FKSGSKVTNTGKEVLCESCVKCPPGSGVGGGGGATATGSPTITSSP
TK-AATLQHHQETVKKQQQLLQNGGKQPDPNDCAGCQQQLKEGQALIALDRQWHIWCFKC
NACGTTLNGEYMGKDGVPYCEKDFQKSFGVKCAHCNRYIS-GKVLQ--------------
---------------------------------------------AGDNHHFHPTCARCT
KCGDPFGDGEEMYLQG-GAIWHPRC-----------GPGPSSEAGIL-------------
---------------------------NGV-DTNGFNTETEFDRTSTSGMS---------
-------EIQ--------------YHR--TTSPGLILREYKNQ----------------G
YEDIARIYTY-----SYLTEEPGYLR-RPIEPYDRA---PVSP--------HFHRPVQ--
HYSSMGVGGTAS--------------------------------SIGKRSASGSRSHSRS
RSAMK-----VLVDSIRSETPRPKSPG-----------MNNEEPIELSHYPAAKKPPPGE
KPKIERDDFPAPPYPYTDPERRRRYSDSYKGVPESDDEVDHANN--KENVTENGKRCVRH
TKEEEELRKLK-SSGMGTVILKDLQEKKRYEHWKQENLDP--RNASRTPSASKEPMYRMR
YESPVGA----SPSRN----LDHQKPFYEDEFDRSTSYRGS------------------V
GRAIGNATSY--------------NAIHSYRSPPKPG------------YGFKTS-TLPP
SLRNGYSSDFS-------------FSGLGDKTHS---TEFSCG----KSDISGDSITEGD
RRAL-GAELPASSTYSGALSYHYPQQPTRRS-LPNMAHSMLVHEPAKI---
>gi|62664515|ref|XP_225889.3|	Rattus norvegicus
------------------------------------------------------------
--------------MNTSIPYQQSPYSPRG--SSNVIQCYRCGDTCKGEVVRVH-NNHFH
IRCFTCQVCGCGLAQSGFFFK-NQEYICTQDYQQLYGTRCDSCRDFITGEVISALGR-TY
HPKCFVCSLCRKP-FPIGDKVTFSGKECVCQTCSQSM------------------TSSKP
IK-IRG-----------------------PSHCAGCKEEIKHGQSLLALDKQWHVSCFKC
QTCSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYIS-GRVLE--------------
---------------------------------------------AG-GKHYHPTCARCV
RCHQMFTEGEEMYLTG-SEVWHPIC-----------KQAARAEKKLK-------------
----------------HRRTSETSISPPGS-SI-GSPNRVICAKVDNEILN--YKDLAAL
PKVKSIYEVQRPNL--ISYEPH--SRY--TSDEMLERCGYGES-LGTLSPY----SQ--D
IYENLDLR-------QRRASSPGYID-SPT--YSQQGMSPTFS----RSPHHYYRSGP--
E--SGRSSPYHS--------------------------------QLDVRSSTPTSYQAPK
HFHIP---A-GE-SNIYRKPPIYKRHG---DLSTATKSKTSEDISQASKYSPAYSPDPYY
AS--ESDYWTYHGSPKV--PRARRFSSG-----GEEDD----------------------
--FDRSMHKL--QSGIGRLILKE----EMKARSSSY-ADP--WTPPRSSTSSREALHTTG
YEMSFNG----SP-------RSHYLADSDPLISKSASLPAY------------------R
RNGLHRTPS---------------ADLFHYDSMNAVN------------WGMREY-----
------------------------------KIYP---YELLLV----TTRGRNRLPKDVD
RTRL-ERHLSQEEFYQ---VFGMTISEFER--LALWKRNELKKQARLF---
>gi|118097291|ref|XP_414527.2|	Gallus gallus
------------------------------------------------------------
--------------MSTSIPYQQNPYTAGS--GSTVIQCYRCGDTCKGEVVRVQ-SNHFH
IRCFTCQVCGWDLAQSGFFFK-NQEYICTHDYQQLYGTRCDSCGDFITGEVISALGR-TY
HPKCFVCSTCRKP-FPIGDKVTFSGKDCVCQNCSHSL------------------ISTKP
IK-IHG-----------------------PSHCAGCKEEIKQGQSLLALEKQWHVSCFKC
QTCGIILTGEYISKDGVPYCESDYHAQFGIKCETCDRYIS-GRVLE--------------
---------------------------------------------TG-SSTYGPDRKRCV
-CYFLVAQALSLCTPG-SEVWHPIC-----------KQAARAEKKLK-------------
----------------HRRTSETSISPPGS-SI-GSPNRVICAKVDNEILN--YKDLAAL
PKIKAIYEVQRPDL--ISYEPY--HRY--TSDETLERYSYGEV-LGTLSPY----SQ--D
IYESFDIR-------QRRASSPGYID-SPT--YSRQGMSPTIP----RSPHHFYRSGT--
E--SGRSSPYYS--------------------------------QLDVRSSTPTSYQAPK
HFHIP---AAGE-SNIYRKPPIYKRHD---NISAATKSKTSEDIAQSSKYSPAYSPDPYY
HS--ESEYWSFQGSPKA--PRARRFSSG-----GEEDG----------------------
--YERGMHKI--QSGIGRLILRE----EMKARSNSY-ADP--WTPPRSSASSREALHTAG
YEGSLNG----SP-------RMHYLADSDPLISKSASLPAY------------------R
RNGLHRPPS---------------AELFHYDSTNAVN------------WGMREY-----
------------------------------KIYP---YELLLV----KTRGRNQLPKDVD
RTRL-ERHLSQEEFYQ---IFGMTIAEFDR--LALWKRNELKKQARLF---
>gi|114602709|ref|XP_001162953.	Pan troglodytes
------------------------------------------------------------
--------------MNTSIPYQQNPYNPRG--SSNVIQCYRCGDTCKGEVVRVH-NNHFH
IRCFTCQVCGCGLAQSGFFFK-NQEYICTQDYQQLYGTRCDSCRDFITGEVISALGR-TY
HPKCFVCSLCRKP-FPIGDKVTFSGKECVCQTCSQSM------------------ASSKP
IK-IRG-----------------------PSHCAGCKEEIKHGQSLLALDKQWHVSCFKC
QTCSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYIS-GRVLE--------------
---------------------------------------------AG-GKHYHPTCARCV
RCHQMFTEGEEMYLTG-SEVWHPIC-----------KQAARAEKKLK-------------
----------------HRRTSETSISPPGS-SI-GSPNRVICAKVDNEILN--YKDLAAL
PKVKSIYEVQRPDL--ISYEPH--SRY--TSDEMLERCGYGES-LGTLSPY----SQ--D
IYENLDLR-------QRRASSPGYID-SPT--YSRQGMSPTFS----RSPHHYYRSGP--
E--SGRSSPYHS--------------------------------QLDVRSSTPTSYQAPK
HFHIP---A-GD-SNIYRKPPIYKRHG---DLSTATKSKTSEDISQTSKYSPIYSPDPYY
AS--ESEYWTYHGSPKV--PRARRFSSG-----GEEDD----------------------
--FDRSMHKL--QSGIGRLILKE----EMKARSSSY-ADP--WTPPRSSTSSREALHTAG
YEMSLNG----SP-------RSHYLADSDPLISKSASLPAY------------------R
RNGLHRTPS---------------ADLFHYDSMNAVN------------WGMREY-----
------------------------------KIYP---YELLLV----TTRGRNRLPKDVD
RTRL-ERHLSQEEFYQ---VFGMTISEFDR--LALWKRNELKKQARLF---
>gi|126291510|ref|XP_001380762.	Monodelphis domestica
--------------------------------------------------MLIESTPSFI
FGTYVCYRFTITVLKNPQFPYQQNPYNPGG--GTNVIQCYRCGDTCKGEVVRVQ-NNHFH
IRCFTCQVCGCDLAQSGFFFK-NREYICTQDYQQLYGTRCHSCRDFITGEVISALGR-TY
HPKCFVCSLCRKP-FPIGDKVTFSGKECVCQTCSNSM------------------ISAKP
IK-VHG-----------------------PSHCAGCKEEIKHGQSLLALEKQWHVSCFKC
QTCGTVLTGEYISKDGVPYCETDYHSQFGIKCETCDRYIS-GRVLE--------------
---------------------------------------------AG-GKHYHPACARCV
RCQQMFTEGEEMYLTG-SEVWHPIC-----------KQAARAEKKLK-------------
----------------HRRTSETSISPPGS-SI-GSPNRVICAKVDNEILN--YKDLAAL
PKIKSIYEVQRPDL--ISYEPY--HRY--TSDEMLERYSYGES-MGTLSPY----SQ--D
IFESLDLR-------QRRASSPGYID-SPT--YSRQGMSPTFP----RSPHHYYRSGA--
E--SGRSSPYHS--------------------------------QLDVRSSTPTSYQAPK
HFHVP---AAGE-SNIYRKPPIYKRHGASKDSSTATKSKTSEDITQSSKYAPAYSPDLYY
GS--ESEFWTYHSSPKV--PRARRFSAG-----GEEDD----------------------
--FDRGLHKI--QSGIGRLILKE----EMKARSSSY-ADP--WTPPRSSTSSREALHTAG
YETSLNG----SP-------RSHYLADSDPLISKSASLPAY------------------R
RNGLHRTPS---------------ADLFHYDSMNAVN------------WGMREY-----
------------------------------KIYP---YELLLV----TTRGRNRLPKDVD
RTRL-ERHLSQEEFYQ---IFGMTITEFDR--LALWKRNELKKQARLF---
>gi|148232702|ref|NP_001081177.	Xenopus laevis
------------------------------------------------------------
--------------------------------MRLMLLC---------------------
--------CSW-----------SEEH----------------------------MGE---
------------------------------------------------------------
EE-GNV-----------------------LPLCASCGQSIYDGCYLQALALDWHSDCFRC
SDCGVSLSHRYYEKDGRLFCKKHYWTRFGGMCQGCSENITKGLVMV--------------
---------------------------------------------AG-EHKYHPECFMCS
RCKAYIGDGETYALVERSKLYCGPCYYQFSVTPVIDSPGSRSPHTVTL------------
-------------VSLPASDGKRGLSVSITPSCAEHSHTVRVTELDADFLG--PDIQSSI
HIGDRILEINGTPIRSVPLDEI--DVL--IQETSRLLQLTIEHDPHETPTM----PSPCA
EIAVRRQRPVMRSCSIDRSPGSSCVG-SPS--CSRRDMSRSESVRTVTGVHRIFRPSDLI
PGEVLGRGCFGQ--------------------------------AIKVTHRVTGEVMVMK
ELIRF---DEETQRTFLKEVKVMRCLEHPHVLKFIGVLYKDKRLNFITEYIPGGTLRRVI
KSMDTHCPWNQRVSFARDIAAGMTYLHSMNIIHRDLNSHN------------------CL
VREDGGLVVA--NFGLSRLIPEETRDLRKDRRKRYTVVGNPYWMAP-------EMINGRS
YDESVDV--------------FSFGIVICEIIGLVNADPDY------------------L
PRTMDFGLN---------------VRAFLDRFCPPNC-----------------------
----------------------------PPGFFP---SAVLCC----DLDPEKRPRFSQL
QLWL-DSLLRHLNLQL---PLSSHIEQLEQNFWENYRRGDSTLHVHPEIPE
>gi|125833789|ref|XP_001339526.	Danio rerio
-------------------------------------------------MGEKSAVHQQK
QPPYDGLCNYAQKITSCFGLDVAHTQESHHQTEKPLIRCAKCGELCKGEVLRVQ-AKHFH
IKCFTCKVCGCDLAQGGFFMK-NGEYLCTLDYQRIHGTRCNICGEFVEGEVVTALGK-TY
HPTCFVCTICKRP-FPAGDRVTFNGKDCLCQYCAEP-------------------MSPGP
TKDVVG-----------------------PSSCAGCGRDIKNGQALLALERQWHLGCFKC
KACAKVLTGEYISKDGAPFCERDYQLQFGVQCEACQQFIT-GKVLE--------------
---------------------------------------------AG-DKHYHPSCARCS
RCNQMFTEGEEMYLQG-STVWHPSC-----------KHSPRGEERQR-------------
---------------PTRSSSESICSRPGS-SIPSSPGHTIYAKVDNEILD--YRDLAAI
PKVKAIYDIERPDL--INYEPL--YTT--SLDESEERESVAEY-PQTRSPT----PSAEG
YYDMRERI-------LHRSTSQGSIG-SPI--YSRHNYTPTLS----RSPQHFHRP----
------------------------------------------------------------
--------DQGM--NIYRKPPIYKQHA-----AFAAQSKSADDIIKSAKFPSAFAPGPDY
PTKIETDCWSFPNFHAALGTDGRRRS-------KEEDEEE---------------IQKRR
QIQEEHLNKI--QSGLGKMILKE----EMEKEKIRE--------------RHARSLSAQR
YEHGSSN--------------------TPHSPSKTGSLPGY------------------G
RNGLHRPQS---------------TDFTQYNSYGDVC------------GGIREFQPMHD
GHRTPTRMDRG----------VSMPNMLEPKVYP---YEMLII----TSRSRSKLPRDVD
RTRL-ERHLAPEVFFE---IFGMEIQEFNR--LPLWKRNELKKKAKLF---
>gi|148705551|gb|EDL37498.1|	Mus musculus
---------------------------------------------VLRILPAPHLPARSS
GCRSAGTTLLGAAADMSAVSQPQAAHAPLEKPASTAILCNTCGNVCKGEVLRVQ-NKYFH
IRCFVCKACGCDLAEGGFFVR-QGEHICTRDYQRLYGTRCFSCDRFIEGEVVSALGK-TY
HPDCFVCAVCRLP-FPPGDRVTFNGKECMCQKCSPPTL-----------------LGNSA
HV-AQG-----------------------LRSCGGCGLEIKNGQALVALDKHWHLGCFKC
KTCGKLLNAEYISKDGLPYCEADYHSKFGIRCDGCEKYIT-GRVLE--------------
---------------------------------------------AG-EKHYHPSCALCV
RCGQMFSEGEEMYLQG-SSIWHPAC-----------RQAARTEDKSK-------------
---------------ETRTSSESIVSVPAS-STSGSPSRVIYAKLGDEILD--YRDLAAL
PKNKAIYNIDRPDM--ISYSPY----I--SHSAVGDRQSYGE-----------------G
DQDDRSYK-------QCRTSSPSSAG-S----VSLGHYTPTS-----RSPQHYSRPAG--
TVSVGTSSCLSLSQHPSPTSVFRHHYIPYFRGSESGRSTPSLSVHSDSRPPSSTYQQAPR
HFHVP---DTGVKDNIYRKPPIYKQHA---------------------------------
---------------------ARRLD-------VEDSS----------------------
--FDQDSRKK-----TTWLLLKG----DADTRTNSPDLDS--QSLSLSSGTDQEPLQRMA
GDSL------------------------------------Y------------------S
REYIPMIPSS--------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
