>gi|74002874|ref|XP_545128.2|	Canis familiaris
-------------------------------------------------------MLEES
KSKEPAMNPFQKNESKETLFSPV-----------STEE-----VPSRPLSLPKTPPP---
-------------KICGSNYPLSIAFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------LYFLHWSEDTSTSIYHA-FSSLCYFTPILGAAIADSWLGKFKTIIYL
SLVYVLGHVVKSLGALPIIGGQ---------TVHTVLSLVGLSLIALGTGGIKPCVAAF-
----------------GGDQFE-EKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQ
C--FG-EDCYALAFGVPGLLMVIALVVFTMGSKIYRKPPPEG-NIVTQVVKCIW------
---------------------FAISNRFNN----RSGD--IPKRQH--W-----------
-----LDWAAEK--------YPK------QLIMDVKALTRVLFLYIPLPMFWALLDQQGS
RWTLQATRMNGN---L-GFFVLQPD----------------QMQVLNPLLVLIFIPLFDL
VIYRLVSKCGISFSSLRKMAVGMILASLAFAVAAAVEIKINK--MTPPQPGPKEIFLQAL
N-LADEEVKVTVLGDE----NNILLEESIRSFQ---KMPHY--AQLHLKTRSQDFHFYLK
YH-------NMSVY-TKHSVEEKNWYSLIIREDGK---NIYSMMVKDE--EN-KTTS---
-GMTALR------FVNTLHKEINI--------------------------------SLGT
DVSLSVGEDYGVSA-----YTTVQSGEYPVVHCRT---EDKDFS------------LNMG
LLESGAAYLFVIINSTNQD---PQAWKMEDI-PANKLSIAWQLPQYALVTAGEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLV------VAQFSGL-VQWAEFILF--S
CLLLVVCLVFSIMGYYYVPIQP------------QDLQE--PADKQIPH----IQGNIIN
LETKKTKL-----------------------
>gi|83766701|dbj|BAE56841.1|	Aspergillus oryzae
-----------------------------------------------------MSDTISR
GKSNALETLKAPLSEQETIVLSA-----------APSP-----HDDGYATPTGEELE---
-----------SLRRVAGSVKWTAYTIAFVELCERFSYYGTTAVF-------VNFIQQPL
PPNSSTGAGHAGQSGALGMGQRVSTGLTTL-NVFWCYVTPIIGAWVADEFWGRLKTIQVA
IAFAMVGHIVLIIASLPQVIVHP--------NGALGCFIVGLVLFGIGVGGFKYRLTFLI
---HKETRHYIKRLPKTGERVI-VDPAQTITRIFLYFYFMINVGSLLGQIVMVYAEKY--
---VG----FWLSFVLPTIMFALCPLVLYVCRKNYEVTPPTG-SVVGRAFKLWA------
---------------------FALKGRCDFWENVKPSN--VQRKPV--W-----------
-----MT-------------FDD------KWVDEVRRALKACAVFLWYPLYWLAYGQMTN
NLTSQAATMELH-----G---VPND----------------IIMNLNPVTLIIFIPIMDQ
VVYPGIQRLGVQFTPLKRMYAGYMLAAISMVSAAVIQHYIYQ--TGKCGKYPGEKSCK--
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------TPAPINVWVQAVPYVLIAFSEIFTSITG
-YEYAFTKAPKNMKSLVQSIYLFMHAFSSAIQQG------LTLLSTDPLLVWNYGFV--A
VLSFIGGNLFWITHHKLDKEED---ELNSLEASSYLGRG--PRAQNKRI----IDIPGAH
IVNKT--------------------------
>gi|50309053|ref|XP_454532.1|	Kluyveromyces lactis
MSAAEKDFLTDDKISDDIINNNNNNNNNNNNNSQALNVDSTVSSDDEFTGEKKDEKFKNN
TDIKVYISKDHHASSDKIDFIGAVD---------EDDN-----QNENGREPTEEELS---
-----------TLRHVSERIPFTCWLIAIVELAERFSYYGLSAPF-------QNYMQNGP
NDTP---------KGVLQLKSQGATALSYF-FQFWCYVTPLLGGYLADTFWGKYNTICVG
ASFYVVGILILFMTAIPSINDK---------NSSLGGFIVSLIIIGIGTGFIKANLSVLI
ADQIPKTRPRIK-VLKNGEKVI-EDPNVTMQNVFMFFYLMINIGSL-SVMATTHLEAS--
---YG----FWAAYLLTFCFFWVGIVVLVFGRKKYVRRPIGD-HVIARCFKICW------
---------------------IGLCNGFNL----NRAV--PSLNPE--------------
-----KEYP-----------WND------LFIDEIRRAFKACKVFAFYPIYWVVYGQMLN
NFVTQAGTMELH-----G---LPND----------------FLQAINSIALIVFIPIMEQ
FIYPFIRRF-TPFRPVTKIFIGFCFGSSAMVYAAVLQHFIYK--AGPCYDFPMSCAPEYA
N-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------TPNRVHIGWQVPAYVLISLSEIFASITG
-LEYAYSKAPATMKAFIMSIFLVTNAVGSALGIA------LSPTAENPKYVWTFSGL--A
VACFIAGCLFWLCFHHYNKDEE---ALNALDYKTEEQEQ-MLSGVGVTG----EGAALYS
VSSVRSRVQQQQKQQNLEHQLSRSA------
>gi|108881208|gb|EAT45433.1|	Aedes aegypti
------------------------------------------------------------
-----------MTEDSKHGEVAT--------------------ANGDGKDVEGADVK---
----------------KLKYPRSIPFIISNEFCERFNYYGMRTIL-------VLYL----
-------------TRKLDYDDDTATVLYHS-FTTLVYFMCVIGAIISDSWLGKFKTILYL
SIVYVCGSTLIAIGAIPTLD-----------LDARAMTVVGLLLIAIGSGGIKPCVAAF-
----------------GGEQFKMPEQAKYLALFFSMFYFAVNSGSFVSTMITPILREDVK
C--FDSDDCFSLAFGVPGILMITSIIIFLFGKPLYKITAPAG-NMFMKVSKCIW------
---------------------TAIRTRSKE----KSVN----PREH--W-----------
-----LDYSEKR--------WGQ------QLVDETKILLNVLRLYIPLPVFWALFDQQGS
RWTFQATRMDGD---L-GFWTIKPD----------------QMQVINPLLILIFIPLYEV
AFYPLLSLLGIR-RPLQKLTLGGIFAGIAFVISTIVEIQLEG--TYAVMPQAGESQLRIF
N-GMPCEYNVRTEVPN----HDTFILKSMEMFE----------EKYIAVNGNKSFTYTFT
SN-----TPGCADFTDRFELEEYKQISYLVNNRDG---EPKLFRYEDNTDKSSK------
-GFPMFR------VLGNTAQDRPI--------------------------------VFKD
LDADPQFDRHSNTT-----YFHDIIESYPSRYEISVDNKK----------------LMEY
SMRLGGVYAFIISENGNE----LKAEAIVVT-EPNSINMLWLVPQYVVMTLGEVMYSITG
-LEFSFTQAPESMKSVLQGCWQLTVAVGNLIVVI------VAEAKIFEAQKWEFVLF--A
CLMFIDMAIFAVLAYYYKPIPI-------KSYSDEDDANTTLPIEDRKD----DRGLENP
TFTKGE-------------------------
>gi|126325751|ref|XP_001363474.	Monodelphis domestica
-------------------------------------------------------MMQLK
QTKEQAMNTFPPKESKETLFALV-----------SPDG-----EVPRSSSPPKKTAL---
-------------KICGSNYPLSIAFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------LYFLHWSEDTSTSVYHA-FSSLCYFTPLLGAAMADSWLGKFRTIVYL
SLVYVLGHLIKSLGALPVVGGH---------LVHTVLSMIGLFLIALGTGGIKPCVAAF-
----------------GGDQFE-DEHVNERSKFFSVFYLSINAGSLISMFVTPMLRGDVK
C--FG-GDCYALAFGVPGMLMILALVVFVLGSKMYKKPPPEG-NIVAQVSKCIW------
---------------------FAISNRLKN----RSRE--IPKRKH--W-----------
-----LDWAEEK--------YPK------QLILDVKALTRVLFLYIPLPMFWALLDQQGS
RWTLQATRMNGN---M-GFFVFQPD----------------QIQVLNPLLVLIFIPMFDL
GLYPLIKKCGINLTSIRKMAAGMILASLAFAIAAAVEIKINE--LTPHKPGGKEVYLRIL
N-LADDEIKVELMGYQ----NKSLFPEPIKPFQ---QTSH---SKMILTMERQHFHFQLL
YH-------NMSIIINEHVMEEKNKYSLVIHGKQS---RISNILMKDA--VT-STAN---
-GMAAVR------FINTLDKDINI--------------------------------TLNR
DVSVSVGQNYGISS-----YKILERGKYHNVLCRM---GDKELF------------LDLG
LLDFGAAYMVAITNSSNQH---LQAWKIEDI-SPNQMSIAWQLPQYVIVTASEVIFSITG
-LEFSYSQAPPSMKSVLQAAWLLTVAIGNIIVLV------VAQTSAL-VQWAEFILF--S
GLLLIICLIFSIMGYYYIPVKP------------EDAYS--LEDTTSSH----IKGDAND
LVSKKTKL-----------------------
>gi|125981837|ref|XP_001354922.	Drosophila pseudoobscura
------------------------------------------------------------
----------------------------------MAFI-----THAVGIENCKSAKE---
----------------VVAYPKSVGFIISNEFCERFNYYGMRTIL-------VLYL----
-------------TNKLGYNEETSTVLFHV-FTMLVYIFPLIGALIADGWLGKYKTILYL
SMVYSVGALIVSFGAIPLSA-----------MPTKAVTILGLILIAVGTGGIKPCVSAF-
----------------GGDQFVLPQQTMQLAKFFSLFYFAINAGSMISTTVTPILRADVH
C--FGEDDCFSLAFGIPAILMIVSVVIFVAGKKRYQINEPTG-NMIFGVSQCLI------
---------------------DAFKGWRKF----RKTD----PMPS--F-----------
-----LDYARHS--------VGA------KMVHETKSLARILILYLPFPIFWALFDQQGS
RWTFQATRMDGL---V-LGFQIKPD----------------QMQVVNPLLILAFIPLFDY
IIYPLLAKVGLR-RPLQKLTVGLLLAALGFFMSAALEMKMEQAASGALPNSPQNAHLRLY
N-GMPCRYEFI--------------------------------SNLSPRTSAQDPSSRSI
DP-------LHMWSDLSLVVKEPTQYTFTAHDPAG-----KCAKIQGQLHLRPGKATSYF
LGDNGLQE-----FDDGLNSVPNI--------------------------------NSPP
LLRALINTPKNEGP-----IMLKGSGDWLQPLSMENRSLSELHKVGFGELNINGKRAASF
QPKNGGLYSLLVNGDAALG---YASNLLEVVPPPTAVSILWQLPQIVAMTAAEIMFSVTG
-LEFSFTQAPQSMKSVLQACWLLSVAIGNMIVVL------IAEFKLASSQSGEFSLF--A
CLMLVDMVLFLWLARNYQYKDQ-----TQESEIPDDVKS--VGKPQTSE----ITSQSKD
KSNLRQEGGMYSEPGYGSYRNNAYENDFSEA
>gi|91078868|ref|XP_972470.1|	Tribolium castaneum
------------------------------------------------------------
MSTETHDTPENGHAS----------------------------NGEEKPKITDGDAG---
-----------EAQLERIPYPKSVFFIISNEFCERFSYYGMRTIL-------SLYL----
-------------RDILDFTEGDSTVIYHT-FTMLAYFFPLLGAIISDNWLGKFKTILYV
SIIYATGNILLALSSAEPLG-----------IPKIPFSLLALFLIAVGTGGIKPCVAAF-
----------------GGDQFVLPQQAVQIATYFSVFYFMINAGSLISTFLTPILREDVH
C--FGQNSCYPLAFAIPGVLMILSVLIFFFGMPLYKMKEPEG-NVLVQVVKCIW------
---------------------HGAKKNWKS----------DKKVDH--W-----------
-----LDHSEDR--------FDR------SLIEDIKATLKVLVIYIPLPIFWACYDQQGS
GWTFQAARMDGR---V-GALTILPD----------------QMQVVNPLLILVFIPLFNY
VVYPACAKINFLKTPLQRMVYGGLLTAIAFAVSACISLAVEG--GDADLPSDGNCQLRIY
N-PYNTTLNLNVKNFA----VNVTSLDPMGYGF----------AQIELT-GDKQLEYEVT
FD--------NQTFSNSFNISEAEGYVLYATETGF----------WETVDDISKPDD---
-GIPKIR-----ILVYNPKNDTAL--------------------------------AFYD
GTAEALKFNSSNVS-----FQSINPGTYIFGNSEY-------------------------
EFNLGGVYTMLLIYFFTHLFS-QKSKLYEIT-EHNNLHILWQLPQCVIITTGEILFSITG
-YEFSYSQAPESMKSVLQAAFLLTSAFGNLIIVI------IESAKIFDKQSYNFFLF--A
GLMALDMILFAFMARNYKYVDK------------SEDKE----NEEDNK----SEKKLSK
SSEENTKF-----------------------
>gi|126132892|ref|XP_001382971.	Pichia stipitis
--------------------------------------------------------MSVS
AQDEKVESLDKQFSSSETDLQAA-----------TNPS-----VEDEGRTPTEDEMK---
-----------TLRHVSESIPISCWLVAIVELAERFSYYGLSAPF-------QNYMQNTP
QDSP---------KGVLGLNQQGATALSYF-FQFWCYVTPILGGWIADTYWGKYKTIFVF
CVIYIVGIFILFITSLPSITSR---------TTALGGYVAAIIIIGLATGGVKSNVSPLI
ADQIPKTHPVIK-VLKSGERVI-QDPNITIQNVFMFFYLMINIGSM-SVIATTQLEAH--
---VG----FWAAYLLPFCFFFIALLALVLGRNQYVKVPVGD-KVINKTFKCAW------
---------------------IGLRNGFNM----DAAR--PSMNPE--------------
-----KEFP-----------WND------HFVDEVVRSVYACKVFVFYPIYWVVYGQMLN
NFVSQAGQMELH-----G---LPND----------------ILQAIDSLVIIIFIPIFER
LVYPFIRKF-TPFKAITKIFWGFMFGAGAMVYAAVLQHYIYK--TGPCYDHPKACAPQYL
N-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------VPNRVHVAIQAPAYFLIAISEILASITG
-LEYAYTKAPVSMKSFIMSLFLLMNAFGSALGIA------LSSTSEDPKMVWTYSGL--A
VSCFIAGIAFWLCFKHYNYKED------ELNALEYDDEE--------ER----NIVPVTS
LSHSVKSLA----------------------
>gi|147902778|ref|NP_001080398.	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
------------------------MFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------LNYLHWDENLSTTVYHA-FSGLCYFTPLIGAPIADAWLGKFNTIFYL
SILYVIGHIIKSVGAIPTVGST---------EVHVALSVIGLIAIAFGTGGIKPCVAAF-
----------------GGDQFE-EEHAQERSKFFSIFYLSINAGSLISTFVTPVLRGDVQ
C--FG-GDCYALAFGVPAALMFVALIVFVAGSGMYKKYPPQG-NILASVFGCIG------
---------------------FALKNRWRH----RSKQ--HPKREH--W-----------
-----LDWADEK--------YQK------RLITEVKMVTKVLFLYIPLPMFWALFDQQGS
RWTLQATRMNSD---F-GGFVLQPD----------------QIQILNPLLILILIPVFDL
GIYPLIRCCKIDFKAIPKMAIGMILAALAFAVATVVEIKINE--TLPPVSAAKESYLQVL
N-LARGELIVEIPGLE-------TIRQPSLHDTNPVDPD-Y--IKLDLLNAHNDFNVELT
QG-------TVKSE-CKLHIEEKSSFSLLVYSEEN---SLNCSLIEES--QT-KPAN---
-GLAMVR------FINMLSDEANV--------------------------------TIG-
DSTVSA-RRGDVSN-----YVTLKRGKIT-ASCLT---ELNTYE------------LDLG
LLNFGATYTVILLMGNDGN---IELKKTEDV-TANSFHVAWQVPQYVLLSAGEVMFSVTG
-LEFSYSQAPTSMKSVLQAGWLFTIAIGNVIVLI------VAQAGTL-EQWAEFILF--A
ALLVAVCIIFSIMGYFYVPANP-----DDL----KDDEE--LEKKQLPD----DNLNAIP
MEEKKTKM-----------------------
>gi|121701539|ref|XP_001269034.	Aspergillus clavatus
-------------------------------------------MSDPVNSADLVTVAQAH
VPKQSLDSPVKETQTSVVFISPN--------------------LDSEGREIPTNEEG---
----------RTLRRVAGKVHWTAYTIAFVELCERFSYYGTTAVF-------VNFIQQPL
PDGSATGAGHSGQSGALGMGQRASTGLTTF-NTFWCYLMPILGAYIADEFWGRLKTIQVS
IAFAMVGHIILIVSALPPVIAHP--------HGALGCFAVGLVIFGIGVGGFKSNIAPLI
AEQHKETRSFIKVIPKTGERVI-VDPAQTITRIFLYFYFMINIGALVGSIAMVYAEKY--
---VG----FWLAFLLPTVMFAVCPAVILICRNKYEVTPPTG-SVSAKAFKLWA------
---------------------FALRGRWSW----NPVKFVQNCRSPDFW-----ENVKPS
KVRNKPEWMT----------FDD------QWVDEVRRAVKACAVFLWYPVYWLAYGQMTN
NLTSQAATMELH-----G---APND----------------LINNLDPLALIIFIPIMDQ
LIYPGIRKLGFNFTPLKKIYVGYIIASMSMIAAAVTQYYIYK--MSPCGDHPSDCD----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------SPAPINVWVQTLPYVLIAFSEIFTSITG
-YEYAFTKAPKNMKSLVQSLYLFMNAISSAIQQG------LTALSTDPLLIWNYGFV--A
VLAFVAGNLFYLTHYQTDLEED---RLNNLEASAYLGTN--------PG----ARNEKID
PEHQVTA------------------------
>gi|157013172|gb|EAA00193.4|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
----------------PVRYPRSIFFIISNEFSERFNYYGMRTVL-------ALYL----
-------------TQKLAYSNDTATVIYHI-FTSLAYFFPLMGAILADSWLGKFKTILYL
SIVYCAGSTLIALGAIPPLN-----------LPATSMTVLGLLFIAVGSGGIKPCVSAF-
----------------GGDQFKLPEQAAQLAKFFSLFYFSINAGSLISTTLTPILREDVH
C--FGDNSCFSLAFGVPAVLMILAIVIFVCGGAMYTIKKPSG-NMIVLVFKCIG------
---------------------NALAVRSKE----SSTS----PRAH--W-----------
-----LDYAESK--------YGK------GIVADIKALLKILILYIPLPVFWALFDQQGS
RWTFQATRMDGE---L-AGYTIKPD----------------QMQVINPLLILAFIPVFES
VIYPALAKIGIR-RPLQKLSLGGLLAGAAFVLSGFVEIALDS--TEAMLPAAHEAQLRVF
N-GLPCDYRFHTDIPN----LAGFSVPSRGAYEALH-------VELPPGLANGTFQFRAE
TSEIGCVRENMTEFSGSFSLQAGGAVSYFISRKGG---RSSLLEYADTAAKDRN------
-GLPRMR------LLANVRTTKQI--------------------------------SLRH
NGNADV--VYNVALNQYDQLTSVTEGEYGVYVGER--------------------PIATV
KLSPGGVYTLILDEFLENE---FNLQTHTIT-PSNSVHMLWLIPQYVVITAGEVMFSITG
-LEFSYSQAPESMKSVIQAFWLLTVAIGNMLVVF------IAEAKFVQSQSLEFFLF--A
ALMFLDMGLFMVLAMRYRYSDT-TGGASSVESIEVEQQG--KKKQHDPL----AISDTLS
ERSAKSTTYANEAYRED--------------
>gi|110767549|ref|XP_001120964.	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------ECSLLSLLLIAIGTGGIKPCVAAF-
----------------GGDQFMLPQQERYLSTFFSLFYFSINSGSLISSFLMPIIRNDIA
C--FGENTCYSLAFFVPAVLMILSIILFIFGKPLYKIVKPTG-NVVLNVSKCIS------
--------------------------------------------DY--W-----------
-----LDYADDK--------YDK------LLINDIKAALQVMILFIPIPIFWALFDQQGS
RWTFQATRMNGE---I-GNFLLQPD----------------QMQVFNPFLVLAFIPLFET
CLYPIMMKFGFR-TPLRIMVIGGFLAALSFVIAAIVEFQLES--TYPVLPSKDFAQLRIF
N-TLNCSIEGKLRDENELSQELSFIVKSMDMWE----------NKYIKANGQKNFSYEVN
FK-------TCNEAGITNISSNKINGSIFVIEAEANSWIITPEGFVDYYKDSIDKSRT--
-GDPLVR---GLIFVNTLK-------------------------------------SISL
ELMKDV--------------------------------------------------QSNI
PFKLGGVYTIVGSVIENK----TNAAMVTVT-DPNSVHILWLIPQYVIITMSEVMFSVTG
-LEFAFTQAPSSMKSLLQACWLLTVAFGNLIVVI------VAEVSIFNRQFAK--IL--P
KSYFTKDILFSIRSLHFVLFI---------------------------------------
-------------------------------
>gi|50288081|ref|XP_446469.1|	Candida glabrata
----------------------------------------------MLNRFSKRNDEKNA
VEVQKDVSSIDDNSSKEVYEIEDQEIHHLDRDKSNAESNFALGEDDDFEAPTEEELK---
-----------TLRHVAGHIPLRCWLIAIVELSERFSYYGLSAPF-------QNYMQNGP
NDNP---------KGLLGLKSQGATGLSYF-FQFWCYVTPVFGGWVSDTYWGKYNTICVG
TFIYVCGIFILFITSIPGVTNS---------DGALGGFIAAIILIGIATGMIKSNLSVLI
ADQLPNKKPRVV-ITKKGERVI-EDPNLTLQNVFMFFYFTINVGSL-SVMATTELEYH--
---KG----FWAAYLLPFCFFWVAVAVLVFGRNQYIKPPVGD-KVISKSFKVLY------
---------------------ILSKNKFNA----EAAK--PSFNPD--------------
-----KNFP-----------WSD------KFVDEIKRALQACKVFVFYPVYWVCYGTMLN
NFVTQGGTMELH--------NLPND----------------FLQAFDSIALIIFIPIFER
FVYPFIRRY-TPLRPITKIFFGFMVGSGAMVWAAVLQHFIYT--KGPWYDHPLDHD----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------TPNHIHVAWQIPAYVLIAISEIFASITG
-LEYAYSKAPESMKSFIMSIFLLTNAFGSAIGCA------LSPVSVDPKFVWFYTGL--A
CACFIAGWVFWFIYSGLNDEEE------AMNALDYEHDE--FMYKHHSD----DEEAAEH
VRSIKSEKS----------------------
>gi|118093817|ref|XP_422093.2|	Gallus gallus
---------------------------------MSDPTFNKGDAKPIGAAYPIAAEPLRS
SRYSSWNQLFPNNGIRTAVNLACVRGPKLWGFESGPGA-----LYIAYLKTKQKP-----
-------------KLCGSNYPLSIAFIVVNEFCERFSYYGMRGMWPVGRDFPILGF----
-------------LYIMAWCSRVLLYVLSVVFQSKLIFWDIIGAIMADSWLGKYKTIIYL
SIVYVVGHLIKSVGAIPSLGNQ---------AVHVVLSMVGLFLIALGTGGIKPCVSAF-
----------------GGDQFE-EEHTSERSKFFSVFYLSINAGSLISTFVTPVLRGDVK
C--FG-EDCYALAFGVPAALMVLALVVFIAGSGLYRKTPPQG-NVLLEVCKCIG------
---------------------FAIKNRLKN----RSHQ--IPKRDH--W-----------
-----LDWASEQ--------YSK------QLIAEVKMVTRVLFLFLPLPMFWALFDQQGS
RWTLQATKMNAD---F-GIYVLQPD----------------QMQFLNPLLILVFIPIFDL
GLYPLISMCKFNFTPIRKMATGMILAGMAFGLAAIVEVKINE--TDMPQLVPKESLIQVL
N-LAKNPVQVTIQDQN-------LFQQPVEAFQ---NPDEY--SHLILNGEQQSLRFILQ
HQ-------GSSLA-FNYTVKEKSVYSLIVFEAEG---SLSSRLITDL--EA-KPEN---
-GLAAVR------FINGLSQDVNL--------------------------------TIDS
KQFIPVQRNYGVSG-----YSLVERDTYDNGKCIT---ETGEFT------------LDLG
LLDFGASYTVVITNVSGGG---VQTWKSEDI-KANNVHMAWQLPQYLLISAGEVMFSITG
-LAFSYSQSPASMKSVLQAGWLLTVAVGNTLVLV------VAQAAPM-AQWAEFVLF--T
VLLFAVCIIFSIMGYFYVSVDP------------EDLEE--KEEKRETP----SRGNMIS
LVTQKTKL-----------------------
>gi|6322946|ref|NP_013019.1|	Saccharomyces cerevisiae
-------------------------------------------MLNHPSQGSDDAQDEKQ
GDFPVIEEEKTQAVTLKDSYVSDDVANSTERYNLSPSP-----EDEDFEGPTEEEMQ---
-----------TLRHVGGKIPMRCWLIAIVELSERFSYYGLSAPF-------QNYMEYGP
NDSP---------KGVLSLNSQGATGLSYF-FQFWCYVTPVFGGYVADTFWGKYNTICCG
TAIYIAGIFILFITSIPSVGNR---------DSAIGGFIAAIILIGIATGMIKANLSVLI
ADQLPKRKPSIK-VLKSGERVI-VDSNITLQNVFMFFYFMINVGSL-SLMATTELEYH--
---KG----FWAAYLLPFCFFWIAVVTLIFGKKQYIQRPIGD-KVIAKSFKVCW------
---------------------ILTKNKFDF----NAAK--PSVHPE--------------
-----KNYP-----------WND------KFVDEIKRALAACKVFIFYPIYWTQYGTMIS
SFITQASMMELH-----G---IPND----------------FLQAFDSIALIIFIPIFEK
FVYPFIRRY-TPLKPITKIFFGFMFGSFAMTWAAVLQSFVYK--AGPWYNEPLGHN----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------TPNHVHVCWQIPAYVLISFSEIFASITG
-LEYAYSKAPASMKSFIMSIFLLTNAFGSAIGCA------LSPVTVDPKFTWLFTGL--A
VACFISGCLFWLCFRKYNDTEE---EMNAMDYEEEDEFDLNPISAPKAN----DIEILEP
MESLRSTTKY---------------------
>gi|74136459|ref|NP_001028125.1	Macaca mulatta
------------------------------------------------------------
------MNPFQKNESKETLFSPV-----------SIED-----VPPRPPSPPKKPSP---
-------------KICGSNYPLSIAFIVVNEFCERFSYYGMKAVL-------ILYF----
-------------LYFLHWNEDTSTSIYHA-FSSLCYFTPILGAAIADSWLGKFKTIIYL
SLVYVLGHVIKSLGALPILGGQ---------VVHTVLSLVGLSLIALGTGGIKPCVAAF-
----------------GGDQFE-EKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQ
C--FG-EDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEG-NIVAQVFKCIW------
---------------------FAISNRFKN----RSGD--IPKRQH--W-----------
-----LDWAAEK--------YPK------QLIMDVKALTRVLFLYIPLPMFWALLDQQGS
RWTLQAIRMNGN---L-GFFVLQPD----------------QMQVLNPLLVLIFIPLFDF
VIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINE--MTPAQPGPQEVFLQVL
N-LADDEVKVTVVGNE----NDSLLIESIKSFQ---KTPQY--SKLHLKTKSQNFHFHLK
YH-------NLSLY-TEHSVQEMNWYSLVIREDGN---SISSMMVKDT--ES-KTTN---
-GMTTVR------FVNTLHKGVNI--------------------------------SLSK
DTSLNVGEDYGVSA-----YRTVQRGEYPAVHCRT---EDKNFS------------LNLG
LLDFGAAYLFVITNNTNQG---LQAWKTEDI-PANKMSIAWQLPQYALVTAGEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLV------VAQFSGL-VQWAEFILF--S
CLLLVICLIFSIMGYYYVPVKT------------EDMQG--PGDKQISH----IQGNMIN
LETKKTKL-----------------------
>gi|150247070|ref|NP_001092848.	Bos taurus
------------------------------------------------------------
----------------------------------------------MGMSVPKS------
---------------C-FGYPLSIFFIVVNEFCERFSYYGMRALL-------ILYF----
-------------QRFLGWNDNLGTAIYHT-FVALCYLTPILGALIADSWLGKFKTIVSL
SIVYTIGQVVIAVSSINDLTDFNHDGTPDSISVHVALSMIGLVLIALGTGGIKPCVSAF-
----------------GGDQFE-EGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQV-
CGIHSKQACYPLAFGVPAALMAVSLIVFVIGSGMYKKVQPQG-NIMSKVARCIG------
---------------------FAIKNRIRH----RSKK--FPKRQH--W-----------
-----LDWASEK--------YDE------RLISQIKMVTRVMFLYIPLPMFWALFDQQGS
RWTLQATTMSGK---I-GIIEIQPD----------------QMQTVNAILIVIMVPIVDA
VVYPLIAKCGLNFTSLKKMTVGMFLASMAFVAAAIVQVEIDK--TLPVFPKGNEVQIKVL
N-IGDSNMTVSFPGTT-------ETYNQMSQP-----------KDFMTFNVDNL-SINIS
ST-------GSPVTPVTHNFESGHRHTLLVWAPSN------YQVVKDG--LNQKPEK---
-GRNGIR------FVNAFGESFNV--------------------------------TMDG
EVYNNVSSHNASE------YLFFSSGVKSFTINS-PEISQPCGK-----------EFKTP
YLGFGSAFTYVITRKSDGC---PEAKAFEDI-SPNTVSMALQIPQYFLLTCGEVVFSVTG
-LEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLI------VAGAGQFSEQWAEYVLF--A
ALLLVVCVIFAIMARFYTYINP-----AEVEAQFDKDDK----EDYLEK----SNPYAKL
DSVSQTQM-----------------------
>gi|114588778|ref|XP_001165943.	Pan troglodytes
------------------------------------------------------------
------MNPFQKNESKETLFSPV-----------SIEE-----VPPRPPSPPKKPSP---
-------------TICGSNYPLSIAFIVVNEFCERFSYYGMKAVL-------ILYF----
-------------LYFLHWNEDTSTSIYHA-FSSLCYFTPILGAAIADSWLGKFKTIIYL
SLVYVLGHVIKSLGALPILGGQ---------VVHTVLSLIGLSLIALGTGGIKPCVAAF-
----------------GGDQFE-EKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQ
C--FG-EDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEG-NIVAQVFKCIW------
---------------------FAMSNRFKN----RSGD--IPKRQH--W-----------
-----LDWAAEK--------YPK------QLIMDVKALTRVLFLYIPLPMFWALLDQQGS
RWTLQAIRMNRN---L-GFFVLQPD----------------QMQVLNPLLVLIFIPLFDF
VIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINE--MAPAQSGPQEVFLQVL
N-LADDEVKVTVVGNE----NNSLLIESIKSFQ---KTPHY--SKLHLKTKSQDFHFHLK
YH-------NLSLY-TEHSVQEKNWYSLVIREDGN---SISSMMVKDT--ES-KTTN---
-GMTTVR------FVNTLHKDVNI--------------------------------SLST
DTSLNVGEDYGVSA-----YRTVQRGEYPAVHCRT---EDKNFS------------LNLG
LLDFGAAYLFVITNNTNQG---LQAWKIEDI-PANKMSIAWQLPQYALVTAGEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLV------VAQFSGL-VQWAEFILF--S
CLLLVICLIFSIMGYYYVPVKT------------EDMRG--PADKHIPH----IQGNMIK
LETKKTKL-----------------------
>gi|68486768|ref|XP_712738.1|	Candida albicans
------------------------------------------------MSTEEKHSQTDV
INSSTQGSHSVEKSSRDDEYAGDNLG--------SDIQ-----IDDEGREPTDHEME---
-----------TLRHVSESIPISCWLVAIVELAERFSYYGLSAPF-------QNYMQFTP
EHSP---------KGMLGLKQQGATALSYF-FQFWCYVTPILGGWISDTYWGKYKTIFVF
CVIYIVGIFLLFITSVPSITSK---------STATGGYIAAIIIIGLGTGGVKSNVSPLI
ADQIPKKKPYIK-VTKKGERVI-VDPNITVQNVFMFFYLMINIGSL-SVIATTQMEAH--
---IG----FWSSYLLTFCFFFIAIAALIVGRNKYVKVPVGD-KIVNKTFKCVW------
---------------------VGIINGFNF----DAAK--PSVKPE--------------
-----KSYP-----------WDD------HFVDEVKRTISACKVFVWYPIYWVQYNGMMN
MFVSSAAGMSRD---------IPND----------------FLTVFDSVAIIVFIPIFER
FLYPFVRHF-TPFKPITKIFWGFMFGSGAMVYAAVLQHYIYK--AGPCYDHPLDCP----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------NGNHINIGLQTPAYVLIAISEILASITG
-LEYAYTKAPVQMKSLVMAMFLLTNAVGAAIGIA------LSSVSVDPKMVWTYSGL--A
VSCFIAGCLFLTLFKHYNKKED---EWNNLEYEANIEEA--------------ALMPVSS
LTPSRKSIA----------------------
>gi|50978676|ref|NP_001003036.1	Canis lupus
------------------------------------------------------------
----------------------------------------------MGMSKSYG------
---------------C-FGYPLSIFFIVVNEFCERFSYYGMRALL-------ILYF----
-------------RRFIGWDDNLSTAIYHT-FVALCYLTPILGALIADSWLGKFKTIVSL
SIVYTIGQAVTAVSSINDLTDYNKDGTPDNLSVHVALSMIGLALIALGTGGIKPCVSAF-
----------------GGDQFE-EGQEKQRNRFFSIFYLAINAGSLISTIVTPMLRVH-E
CGIYSQKACYPLAFGVPAALMAVSLIVFVIGSGMYKKFQPQG-NVMGKVVKCIG------
---------------------FALKNRFRH----RSKQ--FPKREH--W-----------
-----LDWAKEK--------YDE------RLISQIKMVTKVMFLYIPLPMFWALFDQQGS
RWTLQATAMSGK---I-GLLEVQPD----------------QMQTVNAILIVVMVPIMDA
VVYPLIAKCGFNFTSLKRMTVGMFLASMAFVMAAIVQLEIDK--TLPVFPKQNEVQIKVL
N-IGNGAMNVSFPGAV-------VTVSQMSQS-----------DGFMTFDVDKLTSINIS
ST-------GSPVIPVTYNFEQGHRHTLLVWAPNN------YRVVKDG--LNQKPEK---
-GENGIR------FINSLNESLNI--------------------------------TMGD
KVYVNVTSHNASE------YQFFSLGTKNITISSTQQISQNCTK-----------VLQSS
NLEFGSAYTYVIGTQSTGC---PELHMFEDI-SPNTVNMALQIPQYFLITCGEVVFSVTG
-LEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLI------VAGAGQFSEQWAEYILF--A
ALLLVVCVIFAIMARFYTYVNP-----AEIEAQFDDDEK-----KNLEK----MNVYSTV
TPVSQTQM-----------------------
>gi|89886325|ref|NP_001034917.1	Danio rerio
------------------------------------------------------------
--------------------MGK-----------MKDK-----DVDAEKYEKAQRSP---
-------------KLCGTNYPVSIAFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------MNYLHWDKNLSTAIYHA-FSGLCYFTPLLGALIADSWLGKFKTIIYL
SIVYVIGHVVKSVGAIPDVGDS---------TVHIALSMVGLGLIALGTGGIKPCVAAF-
----------------GGDQFD-EDNIDERRKFFSIFYMSINAGSVLSTIITPILRGDVQ
C--FG-GDCYALAFGVPAALMVIALVVFISGSGLYKKSPPEG-NVLVRVCKCIG------
---------------------FAISNRWTN-----SKK--SPKRSH--W-----------
-----LDWAEEK--------YSK------RLIQEIKMVCRVLVLYIPLPMFWALFDQQGS
RWTLQATRMNMD---FGGGFIIKPD----------------QMQMLNALLILVFIPIFDM
GIYPLVGLCRIKLTPLKKMATGMILAALAFCAATAVEVYVIK--TVVEPPPAKESLVQVY
N-LMDSDVTVQFPAHN-------VFSEPLKPYE---EPSGY--SSLPLTGESQLQNVVVS
HN-------GVNYE-CRLTFTERMAYSLLLHPPAQSG-GSVCNLVKDH--IT-KSET---
-GAAYIR------FINTHTENINV--------------------------------TVGT
EEVHAS-ANYGISR-----NISVPRGEYNKAVCVT---DSKEYE------------INLG
LLDFGAFYTVILSE-TGNN---LAIKKMEDI-QANNIHIGWQIPQYVFLTAGEVMFSITG
-LEFSYSQAPASMKSVLQAGWLMTVAFGNVIVLI------VAEGAGM-EQWVEFLLF--A
ALLVAVSIIFSIMAYFYTYVDP-----DQLDKLFKEEGD--GGKVESSK----KDELSLG
EIPKQTKM-----------------------
>gi|149411802|ref|XP_001506250.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------MSKSLS------
---------------C-FGYPVSIFFIIINEFCERFSYYGMRAVL-------VLYF----
-------------QRFLGWNDNLSTAIYHT-FIALCYLTPILGALIADSWLGKFKTIIYL
SIVYTIGQAVTAISSINDLTDSDHDGTPNVMSLHVALSMIGLALIALGTGGIKPCVSAF-
----------------GGDQFE-ESQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQ-E
CGIHSKQSCYPLAFGVPAALMAIALVVFILGSGMYKKVQPQG-NIMAQVAGCIT------
---------------------FAVKNRFNH----RSKT--FPKREH--W-----------
-----LDWASEK--------YDE------RLITQTKMVLKVMFLYIPLPMFWALFDQQGS
RWTLQATTMNGK---F-GSIEIQPD----------------QMQTVNAILIVVMVPVVDG
VIYPLIAKCGFNFTSLKKMTVGMFLASMAFVVAAIIQMQIDK--TLPVFPTAQEFQVRVV
N-LGQESMNVIFPGKE----AVALNLRDKTEF---------------MKLDVNNVNYVVI
ST-------ASTIENHTIPFKEGQRQTLLLWSPSE------FTLLEND--LNKKPEK---
-GLNGIR------FINAMNKSINI--------------------------------TVAG
SNFQDVLPRNASE------YEFFPSG------VKTIMINDKQCE------------GKTG
KLSFGSAYTLVVTKCENGE---SNIIDIEDL-SPNSVSMALQIPQYFLLTCGEVVFSVTG
-LEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLI------VAGAGQFSEQWVEYFLF--A
GLLLVVCVIFAIMAYYYQYVNP-----AEIEAQFDEDEK--KKTGDLQP----NNQNEKP
NTVAQTAL-----------------------
>gi|29468086|gb|AAO16604.1|	Meleagris gallopavo
------------------------------------------------------------
---------------------------------------------MAAKSKSKGSSV---
-------------PNC-FGYPLSIFFIVINEFCERFSYYGMRAVL-------VLYF----
-------------KYFLRWDDNLSTAIYHT-FVALCYLTPILGALIADSWLGKFKTIVSL
SIVYTIGQAVMAISSINDMTDQNRDGNPDNIAVHIALSVTGLILIALGTGGIKPCVSAF-
----------------GGDQFE-EHQEKQRSRFFSIFYLSINAGSLISTVITPILRAQ-E
CGIHSRQQCYPLAFGVPAALMAVSLIVFIAGSGMYKKVQPQG-NIMVQVCKCIG------
---------------------FAIKNRFRH----RSKE--YPKREH--W-----------
-----LDWASEK--------YDK------RLIAQTKMVLKVLFLYIPLPMFWALFDQQGS
RWTLQATTMDGD---F-GALQIQPD----------------QMQTVNPILIIIMVPVVDA
VIYPLIQKCKINFTPLRKITVGMFLAGLAFIAAALVQVQIDK--TLPVFPAAGQAQIRII
N-LGNSNANVTFLPDL-----QNVTVLPMES------------TNYRIFETSQLKSVIIN
F--------GSENRSESIDSTSSNTHTVTIKNAAT---GIVSSLRSDN--FTSKPEE---
-GKNLIR------FVNNLPQTVNI--------------------------------TMG-
DTDFGILEETSISN-----YTLFSGGRTDDIVIVA---DSTNCT------------VTSE
ALGYGGAYTIIINECSEDV---TQLRYIEDI-QPNTVHMAWQIPQYFLLTCGEVVFSVTG
-LEFSYSQAPSNMKSVLQAGWLLTVAFGNIIVLI------VAGASKLSEQWAEYVLF--A
ALLFAVCIIFAVMAYFYTYIDP-----NEVEAQLDEEEK----KKQIKQ----DPDLYGK
ESEADSRM-----------------------
>gi|10946598|ref|NP_067276.1|	Mus musculus
-------------------------------------------------------MLEER
ESKEPAMNPFQKNESKETLFSPV-----------STEE-----MLPGPPSPPKKSTP---
-------------KLFGSSYPLSIAFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------LYFLHWNEDTSTSVYHA-FSSLCYFTPILGAAIADSWLGKFKTIIYL
SLVYVLGHVFKSLGAIPILGGK---------MLHTILSLVGLSLIALGTGGIKPCVAAF-
----------------GGDQFE-EEHAEARTRYFSVFYLSINAGSLISTFITPMLRGDVK
C--FG-EDCYALAFGIPGLLMVLALVVFAMGSKMYRKPPPEG-NIVAQVTKCIW------
---------------------FAICNRFRN----RSED--IPKRQH--W-----------
-----LDWAAEK--------YPK------HLIMDVKALTRILFLYIPLPMFWALLDQQGS
RWTLQANKMDGD---L-GFFVLQPD----------------QMQVLNPFLVLVFIPLFDL
VIYRLISKCGVNFSSLRKMAVGMILACLAFAVAALVEIKING--MIHPQPASQEIFLQVL
N-LADGEIEVTVQGNR----NNPLLVESISSFQ---NTTHY--SKLRLETKSQDLHFHLK
YN-------NLSVH-NEYSVEEKNCYQLVVHENGE---SLSSMLVKDT--GI-KPAN---
-GMTAIR------FINTLHKDMNI--------------------------------SLDA
NAPLSVGKDYGVSE-----YRTVQRGKYPAVHCET---EDNVFS------------LNLG
QLDFGTTYLFVITNITNRG---LQAWKAEDI-PANKLSIAWQLPQYVLVTAAEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLI------VAQFSGL-VQWAEFVLF--S
CLLLVVCLIFSVMGYYYVPLKS------------EGIHE--ATEKQIPH----IQGNMIN
LETKNTRL-----------------------
>gi|119599902|gb|EAW79496.1|	Homo sapiens
------------------------------------------------------------
------MNPFQKNESKETLFSPV-----------SIEE-----VPPRPPSPPKKPSP---
-------------TICGSNYPLSIAFIVVNEFCERFSYYGMKAVL-------ILYF----
-------------LYFLHWNEDTSTSIYHA-FSSLCYFTPILGAAIADSWLGKFKTIIYL
SLVYVLGHVIKSLGALPILGGQ---------VVHTVLSLIGLSLIALGTGGIKPCVAAF-
----------------GGDQFE-EKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQ
C--FG-EDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEG-NIVAQVFKCIW------
---------------------FAISNRFKN----RSGD--IPKRQH--W-----------
-----LDWAAEK--------YPK------QLIMDVKALTRVLFLYIPLPMFWALLDQQGS
RWTLQAIRMNRN---L-GFFVLQPD----------------QMQVLNPLLVLIFIPLFDF
VIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINE--MAPAQPGPQEVFLQVL
N-LADDEVKVTVVGNE----NNSLLIESIKSFQ---KTPHY--SKLHLKTKSQDFHFHLK
YH-------NLSLY-TEHSVQEKNWYSLVIREDGN---SISSMMVKDT--ES-RTTN---
-GMTTVR------FVNTLHKDVNI--------------------------------SLST
DTSLNVGEDYGVSA-----YRTVQRGEYPAVHCRT---EDKNFS------------LNLG
LLDFGAAYLFVITNNTNQG---LQAWKIEDI-PANKMSIAWQLPQYALVTAGEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLV------VAQFSGL-VQWAEFILF--S
CLLLVICLIFSIMGYYYVPVKT------------EDMRG--PADKHIPH----IQGNMIK
LETKKTKL-----------------------
>gi|149731572|ref|XP_001500425.	Equus caballus
------------------MRILVPPLTKARYTSGVTWEFPLFTVGWQLSQLPTEAKCLRR
ESKEPAMNPFQKNESKETLFSPV-----------STEE-----VPPRPPSLPKKPPP---
-------------KICGSNYPLSIAFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------LYFLHWNADTSTSVYHA-FSSLCYFTPILGATIADSWLGRFKTIVYL
SLVYVLGHVIKSLGALPILGGQ---------MVHTVLSLIGLSLIALGTGGIKPCVAAF-
----------------GGDQFE-EKHAEERSRYFSVFYLAINAGSLISTFITPMLRGDVQ
C--FG-EDCYALAFGVPGLLMVIALVVFLMGSKIYRKPPPEG-NIATQVVKCIR------
---------------------FAISNRFKN----RSGD--LPKQQH--W-----------
-----LDWAAEK--------YPK------QLIMDVKALTRILFLYIPLPMFWALLDQQGS
RWTLQATRMNGN---L-GSFVLQPD----------------QMQVLNPFLVLIFIPLFDL
VIYRLISKCGIKFSSLRKMAVGMILACLAFAVAAVVEIKINE--MAPPQPGPQEIFLQVL
N-LADDEVKVTVLGDE----NNSLLVESIKSFQ---KMPHY--SKLHLKTKSQDFHFNLK
YH-------NLSVY-TKHSVEERNWYSLIIRESGK---SISSMMVKDA--EN-KPQTSHK
AGTTAVR------FVNTLHKEVNI--------------------------------SLGA
DISLSVGEDYGVSA-----YRTVQRGEYPAMRCQT---KDKDFS------------LNLG
LLDFGAAYLFVIANRTNQG---PQAWKMEDI-PANKMSVAWQLPQYALVTAGEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLV------VAQFGGL-VQWAEFILF--S
CLLLVVCLIFSVMGYYYVPLKP------------EDIQG--PADKQIPH----TQGNMIN
LETKKTRL-----------------------
>gi|70982510|ref|XP_746783.1|	Aspergillus fumigatus
-------------------------------------------------------MSTKD
HEVEAAQPHLQDNVVSEVALNEK-----------DPYA-----VEKAPLETPDGEEP---
-----TAEEAKNLRHVAENLPVSAWLVAIVELCERFTYYGMSGLF-------QNYVNNPL
DGSKG--------RGALGMGHQGATGLTTF-FQFWCYVTPILGAIIADQYLGKYKTIVLF
CGVYLVGLLILVCTSIPTALEH---------GAGLGGFIVAILVIGLGTGGIKSNVAPLI
ADQYRRKKMAVS-TTKKGERVI-IDPALTIQRIYMIFYGCINLGSL-SLLATPYMERD--
---IG----FWSGYLLCLCMFACGTLVLIVGRKFYVVRPPQG-SIITDAFKALG------
---------------------IMIINRNMD----------APK-----------------
-----PSWQAANGGSRRNLPWDD------HFIDELKRALVACRVFCFFPIYWVVYGQFSG
NFVTQAAQMQGH-----G---IPND----------------LMQNFDPISIIVFIPILET
LVYPLLRRFHIRFRPITRISLGFVVASLAMMYAAIVQHLIYS--AGPCYEHPLCDASKID
G-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------TA-QGNRVHIAIQTPAYMFIGISEIFASVSG
-LEYAYTKAPPSMKSFVQSMYLLTNAFGSAIAEA------LTPAAFDPAIMWMFVGL--A
CASFLVGVIFWLVFHHLNAQED--------------------DMNKLDA----DDPDTPP
PRAREEKN-----------------------
>gi|47222019|emb|CAG08274.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
--------------LCGTNYPTSICFIVVNEFCERFSYYGMKAVL-------TFYF----
-------------ISYLRWDADLSTAIYHA-FSSLCYFTPILGAIIADSWLGKFKTIIYL
SLIYVMGHVIKSVGAIPTVGNK---------DAHISLSMVGLVLIAFGTGGIKPCVSAF-
----------------GGDQFD-EDNLRERQKFFSIFYMSINAGSLLSTVITPILRSDVQ
C--FG-GDCYALAFGVPAALMVVALVVFIAGSGLYKRNPPQG-NVMLRVCKCIGVGGAGG
VGGALFCFFKSLLLFLSFFSQFAIKNRWQ-----RSKH--DPDRKH--W-----------
-----LDWAEEK--------YSK------RLIQEIKMVLRVLVLFIPLPMFWALFDQQGS
RWTIQAARMNMA---FVSPVLSNADGEMPSVSSRTTCRALFPPQMLNAMLILIFVPIFDL
IIYPLVGLCGVKVTPLRKMAAGMVLAALAFGAATLVEVNVVK--TVVDPAPAEHCHLQVF
N-LAPGDVSVAIRGSD-------LFAHPIPSLQVAAAPSCF--NTHTLSGPADGVKVLLL
SA-------RTPPS-TRWLGSKPPAGSCRSRPPSREGRRPVSRWSRSG--RP-TACS---
-WSPRGRTCDANWFFNALPEAVNL--------------------------------TVG-
DVVFSA-GAGEMSP-----NQTVERQRYSSVSCSR---ASKPCP----------P-LDLD
VLEFGASYTVILTE-EDGS---IVPYKMEDV-KANNVHIAFQIPQYALMTAGEVMFSITG
-LEFSYSQAPANMKSVLQAGWLLTVAFGNVIVLI------VAEGAGL-EQWVEFLLF--A
CMLLGVCIVFSIMAHFYTYV----------------------------------------
-------------------------------
>gi|19074905|ref|NP_586411.1|	Encephalitozoon cuniculi
------------------------------------------------------------
------------------------------------------------------------
---------------MTIMNGTTLFLIICNEFCERFCFYGLKSLL-------FSFT----
-------------RSEYGFTIKESTVNLHF-FISMSYLFTLFGGLLSDMFLGRYSTIVLL
SSLYLTGTSLLTYCSIVS--------------GSPGLMVGSLLMIAVGTGGIKPCVAAF-
----------------GGDQFG-PDDAQDLRRFFDFFYFAINIGSMVSMVLTPTM-SSVG
C--LGKQSCYPLAFGTSSTLLGASILLFIIGKRFYVIKPVRK-EQFSRTFHSLV------
---------------------QNLKELFRR----QSRD--SERKTQGTL-----------
-----KTVSEAA--------CIS------HEEDDKEKTLKILRILGPAAFFWMLSDQQSS
SWVEQGTKMETHQSILGYGMDILPS----------------QMQAFNAVFILLFIPLFSK
MIYPLMGLAGVFSSPEEKMGFGIALASLSFFCSGYLEYRIGL-------PAP--------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------AGQRLSIMWQLPQYVLMTAGEIMLNVTG
-MEYMYTEAPEPMKSLVSSMWLLTVTAGNLLVMVLTFLDPVALFSSRAHDMWSFVAYGTA
GLLASRCMFQA------------------------------------------------S
KAAKRNRK-----------------------
>gi|28571098|ref|NP_788855.1|	Drosophila melanogaster
MTDKKNEIQPAAEPVAEPEPSPAAEIAPASPDGSGPSAAAAEEVTPSVATVEDTTPIAAP
AESQPSGESNGTAEAKKLPEIAK-----------KNGK-----EPDQNDKEPDQNGKELA
ETNDFKNVSETEGQQKKLPYPKSVFFIISNEFCERFNYYGMRTVL-------VLYL----
-------------SRVLGYSDDTATVVFHI-FTMFVYFLCVFGAIISDSWLGKFKTILYL
SLVYICGSVLLTLGAIGPLN-----------LPMETFTMLGLALIALGSGGIKPCVSAF-
----------------GGDQFKVPEQVKQITSFFSLFYFSINAGSLISTTVTPILREDVS
C--FDDINCYPLAFGVPAVLMIVSVIIFVLGRSLYKMKPPAG-NMVVLVSSTIW------
---------------------TALTTKCKE----KKTN----PREH--W-----------
-----LDYADKK--------YDR------QLIDDVKVLMRVLFLYLPLPVFWALFDQQGS
RWTFQATRMDGD---M-GSWDIKPD----------------QLQVLNPLLILIFIPLYDV
ALYPALKLVGIR-RPLQKLTMGGILAGIAFIISGVVELSLEH--TYPLIPSSGNTQLRVF
SGIPDCDYRFSTNLGA----RESFTLRGLDFYY----------SGSVATNTDGIFQLTYT
VE--SLTEGCAILEGGTQQLYEATAHSLFLRPSHA----ITKFWYEDEVQKSNRSWA---
-------------FVRNLANLLAT------------------------------------
-TRVVWREDSGDTV-----ALDLPARNHDLYELSTGGYNVQVAD----------HNLTSI
ELRAGGVYALLIGQSHGT----FVSRIIEVT-SPNSMHMLWLVPQYVVMTLGEVMFSVTG
-LEFSYSQSPPSMKSVLQACWLLTVAFGNVIVVV------VAELKFFDSQASEFFLF--A
GLMFVDMLVFMFVAYYYKPYDE--------------VAA--LAERVRAR----RERKWQD
LDRFKRD------------------------
>gi|37778434|gb|AAO31597.1|	Phaeosphaeria nodorum
-----------------MAQAHETTAAEQLVNMQAEANQKPHLFGASVNDANVGANVHVA
DEKEIIEKQSGSNSSGASVRLAD-----------HEEE-----DGLGGVAPTAEELR---
-----------TLRKVGEPLPKSAFLVAVVELCERFTYYGASGLF-------QNYIARPR
SGELG--------RGALGMGHRGATGLSTF-FQFWCYVTPILGAIIADQYLGKYNTIVIF
CGVYMVGLLILTCTSIPAALDH---------GAGLGGFIVAIIVIGLGTGGIKSNVAPLI
ADQYNRKKMVIGHDNNTGEKFI-IDPAITIHRIYMVFYFCINVGCL-SLLATPYMERDID
---------FWSAFLLCLCVFFVGTLVLVLGRKVYVVRPPQG-SVITDAFRVMW------
---------------------LMIKTRKMD----GAKP--SYQAGL--------------
-----GKTTVLR--------WDD------HFVEEVKRALVACKVFCFYPIYWVVYGQFSN
NFITQGGQMATH-----G---IPND----------------LMQNFDPIAIIVFLPLVDQ
VLMPFLRKKKIPFPPINRIVTGFWVASLAMVYAAVIQYYMYQ--TGPCYDHPNCEAAK--
------------------------------------------------------------
------------------------------------------------------------
-GADGVL-----------------------------------------------------
------------------------------------------------------------
--------------------------------HGNNIHIAAQTGAYMLIGISEIFASVTG
-LEYAYTKAPPSMKSFVQSMYLLTNAFGSAISEA------LNPVLYDPNIQWMYVGL--A
VTSFIAGCLIWIIFHHLNETED---EMNQLDRDYDKDET--LRRSSVHA----DRTVGLH
DKDAEKA------------------------
>gi|130483632|ref|NP_001076169.	Oryctolagus cuniculus
------------------------------------------------------------
------MNPFQQNESKETLFSPV-----------STEE-----TPPRLSSPAKKTPP---
-------------KICGSNYPLSIAFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------LYFLHWNEDTSTSVYHA-FSSLCYFTPILGAAIADSWLGKFKTIIYL
SLVNVLGHVIKSLSAFPILGGK---------VVHTVLSLVGLCLIALGTGGIKPCVAAF-
----------------GGDQFE-EKHAEERTRYFSGFYLAINAGSLISTFITPMLRGDVQ
C--FG-EDCYALAFGVPGLLMVIALVVFAMGSKMYKKPPPEG-NIVAQVVKCIW------
---------------------FAISNRFKN----RSED--IPKRQH--W-----------
-----LDWAAEK--------YPK------QLIMDVKTLTRVLFLYIPLPMFWALLDQQGS
RWTLQATKMNGN---L-GFFVLQPD----------------QMQVLNPLLVLIFIPLFDL
VIYRLISKCGINFTSLRKMAVGMVLACLAFAAAATVEIKINE--MAPPQPGSQEILLQVL
N-LADDEVKLTVLGNN----NNSLLADSIKSFQ---KTPHY--SKIHLNTKSQDFYFHLK
YH-------NLSIY-TEHSVEERNWYSLIIREDGK---SISSIMVKDM--EN-ETTY---
-GMTAIR------FINTLQENVNI--------------------------------SLGT
DISLNVGENYGVSA-----YRTVQRGEYPAVHCKT---EDKDFS------------LNLG
LLDFGASYLFVITNSTKQG---LQAWKMEDI-PANKVSIAWQLPQYALVTAGEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTVAIGNIIVLV------VAQFSGL-VQWAEFVLF--S
CLLLVVCLIFSIMGYYYIPIKS------------EDIQG--PEDKQIPH----MQGNMIN
LETKKTKL-----------------------
>gi|149060553|gb|EDM11267.1|	Rattus norvegicus
-------------------------------------------------------MLEER
ESKEPAMNPFQKNESKETLFSPV-----------STEE-----MLPRPPSPPKKSPP---
-------------KIFGSSYPVSIAFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------LYFLHWNEDTSTSVYHA-FSSLCYFTPILGAAIADSWLGKFKTIIYL
SLVYVLGHVFKSLGAIPILGGK---------MLHTILSLVGLSLIALGTGGIKPCVAAF-
----------------GGDQFE-EEHAEARTRYFSVFYLAINAGSLISTFITPMLRGDVK
C--FG-QDCYALAFGVPGLLMVLALVVFAMGSKMYRKPPPEG-NIVAQVIKCIW------
---------------------FALCNRFRN----RSGD--LPKRQH--W-----------
-----LDWAAEK--------YPK------HLIADVKALTRVLFLYIPLPMFWALLDQQGS
RWTLQANKMNGD---L-GFFVLQPD----------------QMQVLNPFLVLIFIPLFDL
VIYRLISKCRINFSSLRKMAVGMILACLAFAVAALVETKING--MIHPQPASQEIFLQVL
N-LADGDVKVTVLGSR----NNSLLVESVSSFQ---NTTHY--SKLHLEAKSQDLHFHLK
YN-------SLSVH-NDHSVEEKNCYQLLIHQDGE---SISSMLVKDT--GI-KPAN---
-GMAAIR------FINTLHKDLNI--------------------------------SLDT
DAPLSVGKDYGVSA-----YRTVLRGKYPAVHCET---EDKVFS------------LDLG
QLDFGTTYLFVITNITSQG---LQAWKAEDI-PVNKLSIAWQLPQYVLVTAAEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLV------VAQFSGL-AQWAEFVLF--S
CLLLVVCLIFSVMAYYYVPLKS------------EDTRE--ATDKQIPA----VQGNMIN
LETKNTRL-----------------------
>gi|72088458|ref|XP_792746.1|	Strongylocentrotus purpuratus
-----------------------------------------------------------M
SGSSLIDRPQEQA------------------------------ISGKGWGRVRKFVT---
---------------GQSGFPKSVFFIVGTEFCERFSFYGMKAIL-------VLYL----
-------------TNILLLGDNTSTAIFHS-FNMLCYFSPIFGAMIADGWLGKYKTIVYI
AQIYMLGNAVMCLTALPPQTTG---------HPYMIGPAIGLLLIGVGTGGIKPCVSAF-
----------------GGDQFK-ADQEKEIQRFFSVFYFSINSGSLLSTFVTPILRHDVQ
C--FG-NDCYTLAFGVPAVLMAVSIIIFILGRNFYQHNPPTG-NIVGEVVKAMG------
---------------------FAVKNRFQN----RSS---PEKKQH--W-----------
-----LDWAEEK--------YGA------ALIEDIKVLLHVLFIFLPLPFFWALFDQQGS
RWTLQAEHMDGR---L-GSYQIKPD----------------QMQAMNPVFILIFIPLFEG
VIYPLLDKCNVPKRPLQRMAGGMTLAAIAFVFAGFLQLKIDS--SELSLPGPGQSVVSVI
N-ASPCPINVESKFYT----GPIDVAGGT--------------KKIDFAVGDYDIKFEPG
CS------ELGTAQPFSASLGSQLVESVIVYSSAN---QLQALQVKGHLEKSHE------
-GLGKLR---THVLLNNVSSSLDV------------------------------------
-----------------------EPGQYSVYGVPVGNASKVL--------------LGDI
DVKMGGIYRLLIQPANISQSDTIRLAIHTEV-QPNSVSMLLQIPQYIVITCGEILFSVTG
-LEFSYSQAPASMKSCVQAAWLMTVAFGNLIVVI------IAESQIIDSQAMEFFLF--A
GLMGFIILLFSIMAWCYVYVTP-----RSPDLQMHDTAG-LVTNSDMED----PGTDSSH
RDTQKSAIKFPLQNAIL--------------
>gi|57619301|ref|NP_001009758.1	Ovis aries
------------------------------------------------------------
----------------------------------------------MGMSVPKS------
---------------C-FGYPLSIFFIVVNEFCERFSYYGMRALL-------ILYF----
-------------QRFLGWNDNLGTAIYHT-FVALCYLTPILGALIADSWLGKFKTIVSL
SIVYTIGQVVIAVSSINDLTDFNHDGTPNNISVHVALSMIGLVLIALGTGGIKPCVSAF-
----------------GGDQFE-EGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQV-
CGIHSKQACYPLAFGVPAALMAVSLIVFVIGSGMYKKVQPQG-NIMSKVARCIG------
---------------------FAIKNRISH----RSKK--FPKREH--W-----------
-----LDWASEK--------YDE------RLISQIKMVTRVMFLYIPLPMFWALFDQQGS
RWTLQATTMSGK---I-GIIEIQPD----------------QMQTVNAILIVVMVPIVDA
VVYPLIAKCGLNFTSLKKMTVGMFLASMAFVAAAIVQVDIDK--TLPVFPKGNEVQIKVL
N-IGNNSMTVSFPGTT-------VTCDQMSQT-----------NGFLTFNVDNL-SINIS
ST-------GTPVTPVTHNFESGHRHTLLVWAPSN------YQVVKDG--LNQKPEK---
-GRNGIR------FVNAFGESFGV--------------------------------TMDG
EVYNNVSGHNASE------YLFFSSGVKSFTINS-PEISQQCEK-----------QFKTS
YLEFGSAFTYVISRKSDGC---PEPKIFEDI-SPNTVSMALQIPQYFLLTCGEVVFSITG
-LEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLI------VAGAGQFSEQWAEYVLF--A
ALLLVVCIIFAIMARFYTYVNP-----AEIEAQFDEDDK----EDDLEK----SNPYAKL
DFVSQTQM-----------------------
>gi|156555308|ref|XP_001603652.	Nasonia vitripennis
------------------------------------------------------------
------------------MYYIH-----------SSAQ-----QARRVATFDSESRE---
---------------RKLKYPKSVFFIICNEFCERFSYYGMRTVL-------SFYL----
-------------VDILLYTQTMATVIYHT-FTMFAYFFPLLGAMLADSYLGKYRTILYL
SVVYAAGQLLLAVSSVPPLG-----------LPVREFSILGLLMIALGTGGIKPCVAAF-
----------------GGDQFKLPQQEHYLAVFFSLFYFSINSGSLISTAITPVLRKEVT
C--YGMTTCYPLAFLVPAVLMTVSIVIFFAGKRLYKIRQPEG-NVVVKVVLCIS------
---------------------HAIGRKIKS----------KGKREH--W-----------
-----LDYSDDK--------YDR------HLIEDIKSVLKVLVLFVPLPFFWALFDQQGS
RWTFQASRMDGE---V-FGYLIKPD----------------QFQVINPLFIVIFIPVFQW
AIYPILEKFLYLNTPLRKMTAGGILAGLSFIISAIVELNIEP--TYAVQPSQGLAQIRIF
N-TINCPASLTLGSST----NKTSYSLEALNMIQD--------LYVPVNNSSTVLTLDAK
YTDCKQLPGGTLTVSENLTLVEKTATSWALTIEGL------SPPFADSVEKSGTGDP---
-------------FVRALIYKTTS--------------------------------KINS
TINFNGEKENQINITKKLQFTEFDKINHNPYNITL---DGKPVE-------------DNV
FFRFGGVYNIIGYASDTD----AAAKTVTLA-DPNSVHMFWLMPQYVVITMGEIMFSITG
-LEFAFTQAPVTMKSLLQASWLLSVAFGNLIVVI------IAEAAFFDRQVFEFFLF--A
GLMFVDMIIFAIMARCYKYVEP--SELASMSFEEDENRG--KLKNSSPRFSSVHRAEMKS
AHSPSARA-----------------------
>gi|147905019|ref|NP_001090983.	Sus scrofa
------------------------------------------------------------
------MNPFQKNESKETLFLPV-----------STEE-----VPPRPPSFPKKPSP---
-------------KICGSNYPLSIAFIVVNEFCERFSYYGMKAVL-------TLYF----
-------------LYFLHWSEDTSTSVYHA-FSSLCYFTPILGAAIADSWLGKFKTIIYL
SLVYVLGHVIKSLGALPILGGH---------MIHTILSMVGLSLIALGTGGIKPCVAAF-
----------------GGDQFE-EKHAEERTRYFSVFYLSINAGSLISTFVTPMLRGDVQ
C--FG-KDCYALAFGVPGMLMIIALVVFSMGSKIYKKPPPEG-NIVTQVVRCIW------
---------------------FAISNRFKN----RSGD--IPKREH--W-----------
-----LDWASEK--------YSK------QLIMDVKALTRILFLYIPLPMFWALLDQQGS
RWTLQATRMNGN---L-GFFVLQPD----------------QMQVLNPFLVLIFIPLFDL
VVYRLVAKCGINFTSLRKMAVGMILACLAFAVAAAVEIKING--MAPPQPDSQEGFLQVL
N-LANDEVKVTVLGNE----NSSLLEESIKSFQ---TMPHY--SKLHLKTKREDFHFQLK
YH-------NLSVY-TEHSVEEKKLYTLIIREDGK---SISSMMVKDA--ES-RATN---
-GMTAMR------FVNTLHEEVNI--------------------------------SLGT
DTSFSVGKDYGVSA-----YRTVQRGEYPVVHCRT---KDENFS------------LNLG
LLDFGAAYLFVITNSTGQG---PRVQKIEYT-PANKMSIAWQLPQYALVTAGEVMFSVTG
-LEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLI------VAQFSGL-VQWAEFILF--S
CLLLVVCLIFSIMGYYYIPIKP------------EDIQG--SADKQIPQ----IQGNMIN
LETKKTKL-----------------------
>gi|34014960|gb|AAQ56235.1|	Macaca fascicularis
------------------------------------------------------------
----------------------------------------------MGMSKSQG------
---------------C-FGYPLSIFFIVANEFCERFSYYGMRGIL-------ILYF----
-------------TNFFSWDDNMSTAIYHT-FVALCYLTPILGALIADSWLGKFKTIVSL
SIVYTIGQAVISVSSINDLTDHNHDGTPDSLPVHVALSMIGLALIALGTGGIKPCVSAF-
----------------GGDQFE-EGQEKRRNRFFSMFYLAINAGSLLSTIITPMLRVQ-Q
CGIHSKQACYPLAFGVPAALMAVALIVFILGSGMYKKFQPQG-NIMGKVAKCIH------
---------------------FAIKNRFRH----RSKA--FPKREH--W-----------
-----LDWAKEK--------YDE------RLISQIKMVMRVMFLYIPLPMFWALFDQQGS
RWTLQAATMSGK---I-GALEIQPD----------------QMQTVNAILIVIMVPIFDA
VLYPLIAKCGLNFTSLKKMTVGMFLASLAFVVAAIVQVEIDK--TLPVFPKGNEIQIKVL
N-IGNTTMNISLPGEM-------VTLDSLSQT-----------NAYMTFDVNKLTSINIS
SP-------GSPVTAVTDDFKQGQRHTLLVWAPNH------YRVVKDD--LNQKPKK---
-GENGIR------FVNTFNELITV--------------------------------TMSG
KIYANVSSNNASN------YQFFPSGIKGFTISS-TEIPPQCQP-----------NFHTH
YLEFGSAYTYLVRRKNGSC---PEVRSFEDI-SANTVNMALQIPQYFLLTCGEVVFSVTG
-LEFSYSQAPSNMKSVLQAGWLLTVAIGNIIVLI------VAGAGQFSKQWAEYILF--A
ALLLVVCIIFAIMTRFYTYINP-----AEIEAQFDEDEK----KKSLEN----SNPYIML
GANSQTQM-----------------------
