>gi|91076770|ref|XP_973750.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MDQIPPPKEVKILE-----TAEDIQERRQQVLSRYDNFK
ADVRAKREKLEDSRR--FQYFKRDADELES-----WILEK--------------------
---------LQAASDESYKDPTNLQAKIQKHQAFEAEVAAHSNAIVVLDNTGREMINQNH
YESETIRRRLEELHRLWEQLLSKLAEKGMKLQQALVLVQFIRQCDEVMFWINDKSTFLTT
EEFGHDLEHVEVLQRKFD--EFQKDMASQEHRVTQVNELADKLLQDGHPERDTIINRKEE
LNNAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKQMTLMRQDKLYGAHEIQRFNRDADETVAW-IAEKDV
----VLSSDDYG------------------------------------------------
---------------------------------------------------RDLASVQAL
QRKHEGVERDLAALEDKVSTIGKEADRLCAIH-GDHADQIQSKRAEIEDYWQSLTAKAKE
RRDKLLESYALHRFLSDFRDLVSWINDMKAIISADELAKDVAGAEALLERHQEHRGEIDA
REDSFAATTEAGRLLLENGHYASDEVKEK----------------------------LST
LVSDKNSLLALWEERRILYEQCMDLQLFYRDTEQADTWMAKQEAFLANEDLGDSLDSVEA
LIKKHEDFEKSLAAQEEKIKALDEFATKLIDGEHYAADDVAQRRAMLLERRSALKEKSAQ
RRALLEDAYKLQQFERDCDETKGWINEKLKFATD-ESY-LDPTNLGGKVQKHQNFEQELN
ANKTRME-----DITSTGQELVDAKHYAAPRIQSRMEEIVNLWETLVQSTDKKSSKLQEA
SQQQQFNRTIEDVELWLSEIEGQLMS------------EDYGKDLTSVQNLQKK------
---------------HALLEAD-VASHQDRIEGITAAANQFV-----ERGHF---DADNI
AHKQKVLTDRYTALQTPMAIRKQRLLDSLQVQQLFRDIEDEEAWIREKEPIAAGTTRGR-
--------------DLIGVQNLIKKHQAVLAEINNHDARISAVVEAGRQMMEDE------
--HFASDQIRNRVTALNDHWVQLKEKANQRKQDLDDSLQAHQYYADANEAESWMKEKEPI
VSNTDYGKDEDSSEALLKKHEALMSDLIAFGNTIEGLKEQARNCRQQEP-PVVDVTGRET
VQALYDYTEKSAREVSMKKGDLLHLLNSSNK-----------------------------
------------DWWKVEIHDRQGFVPAAYVKKV--DAGLTASQQNLV-DNNSISARQNQ
INTQ--------------------------------------------------------
-------------------------------------YDRLLALARERQNKLNETVKAYV
LVREAAELANWIKDKEMHAQVQD-VGEDLEQVEVMQKKFDDFQTDLKAN-EVRLAEMN--
------------------------------------EIAMQLVSLG-QTEAALKIQTQ--
------------------------------------------------------------
---MEDLNTKWTSLQQLTAERANQLGSAHEVQRFHRDVNETIDWIQEKDEALNNDDL-GK
DLRSVQALQRKHEGLERDLAALGDKIKQLDEI--AGRLVQTHP-ESAEQTRAKQEEINEL
WTQLTAKANNRKEKLLDSYDLQRFLNDHRDLMAWMNSMLGLVTSTE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LASDVTGSEALIERHQEHRTEIDARAGTFNALEQFGQQLLSS
QHY-ASP--EIQEKLEQLNEFRKELETRWIERRVQLDQNLDLNLFYRDCEQAENWMSDRE
AFLAS--DEVDSNTDNVEALIKKHEDFDKAINAHEEKIAALESLANQLIQNEHYASQDID
NKRKQVLDRWHHLKEALIEKRSKLGESQTLQQFSRDADEIENWIAEKLQLATEESYKDPA
NIQ------------SKHQKHQAFEAELAANADRIQSVLSNGTNLIEKRQCAGSEEAVQK
RLESIADQWEFLTQK-TTEKSMKLKEANKQRTYIAAVKDLDFWLG---------------
----EVESLLTSEDAGKDLASVQNLMKKHQLVEADIQAHEDRIKDMNDQADSLIESGQFD
TASIQEKRQSINERYERIKNLAAHRQARLNEANTLHQ-FFRDIADEESWIKEKKLLVGSD
DYGRDLTGVQN-------------LKKKHKRLEAELGSHEPAIQAVQEAGEKLM---DVS
NLGVPEIEQRLKALNQAWAELKQLAATRGQKLDESLTYQQFLAKVEEEEAWISEKQQLLS
VEDYGDTMAAVQGLLKKHDAFETDFQAHRERCKDINDAGKKLVAEGNHHADSINQRCQQL
QTKLDHLAALAGRRKAKLIDNSAYLQFMWKADVVESWIADKETHV--KSEEYGRDLSSVQ
TLLTKQETFDAG--------------LTAFEHEGIQNITALKDQLIASNHDQSPAILQRH
ADVIDRWQKLLADSDARKQRLLHMQDQFRQIEDLFLTFAKRASAFNSWFENA----EEDL
---TDPVRCNSIEEIRALREAHAQFQASLSSAQADFEALAALDQQIKSFNVGPNPYTWFN
MEA-LEETWRNLQKIIAERDVEL----------------------------NKEAQRQEE
--------NDKLRKEFAKHANAFHQWLTETRTSMMEG-----------------------
----SGSLEQQLEATKRKAAEVRAR-----------------------------------
------------------------------------------RSDLKKIEDLGAILEEHL
ILDNRYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNQSGVSEDALK------------------EFS
MMFKHFDKEKSGK---------------LNHQEFKSC-----------------------
-------LRAL---------------------GYDLPMV---------------------
EEGQPDPEFDAILDVVDPN-----RDG----------HVSLQEYMA--------------
-FMISKET----------------------ENVQSSEEIEKAFRAITAGD---RP-----
---------YVTQEELYANLTKEMAD---YCVA-----RMKPYVEPKTERTIAGALDYIE
FTRTLFQN---------------------------------------
>gi|148692241|gb|EDL24188.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------RIWPSGGPVGPNRA---GPGPATNARR
EGGAARRASGTASAAGAQALPPPMAQVPGEVDNMEGPAVSNNNNPSARWESPDRGWDREP
PAAANAAASLFECSR--IKALADEREAVQKKTFTKWVNSH--------------------
---------LARVGCHIG----DLYADLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHS--
------------------------------LENVDKALQFLKEQRVHLENVGSHDIVDGN
HRLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNI-----QN
FTTSWRD-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------GLAFNALIHRHRPDLVDLSKLTKSNANYNLQRAFRTAEQHL
GLARLLDPEDVN------------------------------------------------
---------------------------------------------------MEAPDEKSI
ITYVVSFYHYFS----KMKALAVEGKRIGKV--LDQVLEV----DKIIERYEELAA----
-------------------ELLAWIHRTVDLISNQKFANSLSGVQQQLQAFTAY------
------CTLEKPVKFQEKGN-------------------------------------LEV
LLFSIQSKLRAHNRR------------LFVPREGCGIW-----------DIDKAWGELE-
----KAEHEREAALRAELIR---------------------QEKLELLAQR---------
-------------FDHKVAMRESWLNENQRLVSQ-DNFGYELPAVEAAMKKHEAIEADIA
AYEERVQ-----GVAELAQALAAEGYYDARRVAAQRDSVLRQWALLTGLVGARRTRLEQN
LALQKVFQEMVYMVDWMEEMQTQLLS------------RECGQHLVEADDLLQK------
---------------HGLLEGD-IAAQSERVEALNAAALRFS-----QLQGYQPCDPQVI
CNRVNHVHGCLSELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEATSGSG-
-GAAGTAG---GAHDLSSTARLLAQHKILQGELGGRRALLQQALRRGEELAAAGGSVGPG
AEPLHLAGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRL
AAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVGGLRRQLA--------TLGGASGAGP
LVV---------------------------------------------------------
----------------------------------------------------ALQVRVVE
AEQL--------------------------------------------------------
-------------------------------------FAEVTEVAALRRQWLRDALAVYR
MFGEVHACELWIGEKEQWLLAMR-VPDSLDDVEVVQHRFESLDQEMNSL-MGRVLDVN--
------------------------------------QTVQELVEGG--HPSSDEVRSC--
------------------------------------------------------------
---QDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAPRAGG
------ALQWRLSGLEAALQALEPRQAALLEE--AALLAERFP-AQATRLHQGAEELGAE
WGALAGAAQACGEAVAAAGRLQRFLRDLDTFLDWLVRAQEAAGAVEG-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------PLPRSLEEADGLLARHAALKEEVDQREEDYARIVAASEALLAS
EGAELGPGLALDEWLPHLEVGWHKLLGLWEERREALVQAHVYQLFLRDLCQALAVLRNQE
VALSG--AELPCTVESVEEAMKRHRDFLTTMELNQQKMQVAVQAAESLLRQGNAYGEQAQ
EAVARLLEKSQENQLRAQQWMQKLLDQLVLQHFLRDCHELDGWIHEKMLMARDGTREDSH
KLH------------KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAA--SVRK
KLGEIRQCWAELEST-TQAKARQLFEASKADQLVQSFAELDKRLL---------------
----HMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQTAAL-PLEQAS
KELVGERQSAVGERLVRLLEPLQERRRLLLASKELHQ-VAHDLDDELAWVQERLPLAMQT
ERGTGLQAVQQ-------------HIKKNQGLRREIQAHGPRLEEVLERAGVLA---SLR
SPEAEAVRRGQEQLQSAWTGLREAAERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMM
SEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQV
DRLYVALKELGEERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVA--GSPELGQDFEHVS
VLQEKFSEFASE--------------TGTAGRERLAAVNQMVDELIECGHTAAATMAEWK
DGLNEAWAELLELMGTRAQLLAASRELHK--------FFSDARELQGQIEEK----RRRL
PRLTAPPEPRP--SASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIAS
REQEVLQGWKELLAACEDARLHVSSTADALRFHSQARDLLSWMDGIAGQIGAADKPRDVS
SVEVLMNYHQGLKTELEARVPELATCQELGRSLLLNK-----------------------
-SAMADEIQAQLDKLGSRKEEVSEKWDRHWEWL---------------------------
--------------------QQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVE
QLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRKFFGDPTELAAKA
APLLRPGGYDRGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPETSGKVEP
AAPTAAALDTTDTPGTPA--ATELVRPRSERQELADRAE------------------ELP
RRRRSERQESVDQPEETARRRRPERQESADHEGPHSLTLGRYEQMERRRERRERRIERQE
SSEQETPTRGELVKGKATLADIVEQLQEKEA-GPGIPAGVPSLPQPRELPPGRLPNGLEP
PERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHE
GFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGFYKDSKGPASGGTHGG---EPLLSLH
KATSEVASDYKKKKHVFKLQTQDGSE---FLLQAKDEEEMNGWLEAV-ANSVAEHAEIAR
WGQTLPTTSSTDEGNPKREGGERRASGRRK-----------------
>gi|66513649|ref|XP_623691.1|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MDQITPKEVKILE-----NPEDIQERREQVLSRYANFK
AEAKNKRDKLEDSRR--FQYFKRDADELEG-----WIFEK--------------------
---------LQAASDESYKDPTNLQAKIQKHQAFEAEVAAHSNAIVSLDNTGSEMIAQHH
FASDVIRKRLADLHQLWELLLSRLADKGLKLQQALVLVQFMRHCDEVMFWIHDKEAFVTT
DEFGHDLEHVEVLQRKFD--EFQKDMASQEYRVTEVNELADKLLLDGHPERDTILRRKEE
LNESWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKQLAVLRQEKLFGAHEIQRFNRDADETMAW-IAEKDV
----VLSSDDFG------------------------------------------------
---------------------------------------------------RDLASVQTL
QRKHEGIERDLAALEDKVYTLGAEADRLAAIHQADHSKQIQAKRAEILQSWESLTAKAKE
RRLKLDESYYLHRFLADYRDLVSWMNDMRAIISADELAKDVAGAEALVERHQEHKGEIDA
RADSFDATTLAGNKLLEKKHYAAEEVTRK----------------------------LNS
LAEDKQSLLNLWEKRKILYEQCMDLQLFYRDTEQADAWMAKQEAFLANEDLGDSLDSVEA
LIKKHEDFDKSLAAQEEKIKILDEFAGKLIEGEHYAADDVAQRRQLLLERRAILLEKSAQ
RRRRLEDAYKLQQFERDCDETKGWVNEKLKFATD-DSY-LDPTNLNGKVQKHQNFEQELN
ANRTRME-----EMVATGQELIESDHYASDRIRTRTDEIMSLWESLTHATEKKGAKLQEA
SQQQQFNRTVEDIELWLSEVEGQLMS------------EDYGKDLTSVQNLQKK------
---------------HALLEAD-VASHSDRIESIAQAADQFV-----KSGHF---DADNI
KAKQEQLQARYAALQQPMNIRKQRLLDSLQVQQLFRDIEDEEAWIREKEPVAASTNRGR-
--------------DLIGVQNLQKKHQAVLAEINNHEPRVAAVCQAGASMLQES------
--HFAAEEISQRLAALDEHWGQLKEKARQRKNDLDDSLQAHQYFADANEAESWMKEKRPI
VMNADYGKDEDSSEALLKKHEALVSDLEAFASTIAALRDQAASCRQQET-PTVDITGKEC
VVALYDYTEKSPREVSMKKGDTLTLLNSNNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKRVEPEAGLSASQQNLAREQSSIAARQAQ
IEAQ--------------------------------------------------------
-------------------------------------YDDLLRLARERQNKLNETAKAYV
LVREAAELATWIKDKENHAQVQD-VGEDLEQVEVMQKKFDDFQADLKAN-EVRLAEMN--
------------------------------------EIAVQLMSLG-QTEAALKIQTQ--
------------------------------------------------------------
---IQDLNEKWTSLQTLTAERANQLGSAHEVQRFHRDVDETKDWIREKDAALNNDDL-GK
DLRSVQALQRKHEGLERDLAALGDKIKQLDET--ANRLMQSHP-ETAEQTYAKQKEINEE
WTQLTAKANSRKEKLLDSYDLQRFLSDYRDLMAWINSMMGLVASEE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LASDVTGAEALLERHQEHRMEIDARAGTFQAFELFGQQLLQS
SHY-ASV--EIQEKLESMAEARQELEKAWIQRRMQLDQNLELQLFCRDCEQAENWMSARE
AFLSS--ADTVDSSDNVEALIKKHEDFDKAINAHEEKIATLQTLADQLIAAEHYAAKPID
ERRCQVLDRWKHLKDALIEKRSKLGESQTLQQFSRDADEMENWIAEKLQLATEENYKDPA
NIQ------------SKHQKHQAFEAELAANADRIQSVLAMGGNLIEKHQCAGSEDAVQK
RLASIADQWEYLTQK-TTEKSMKLKEANKQRTYIAAVKDLDFWLG---------------
----EVESLLTSEDAGKDLASVQNLMKKHQLVEADIQAHEERIKDMNAQADSLIESGQFD
AAGIQEKRQSINERYERIRNLAAHRQARLNEANTLHQ-FFRDIADEESWIKEKKLLVGSD
DYGRDLTGVQN-------------LKKKHKRLEAELGSHEPAIQAVQEAGEKLM---DVS
NLGVPEIEQRLKLLNQAWAELKQLAANRGQKLDESLTYQQFLAKVEEEEAWITEKQQLLS
VEDYGDTMAAVQGLLKKHDAFETDFAAHGERCKDICEAGEALIKAGNHRADAIGQRCAQL
RNKLEQLGALAARRKTRLNDNSAYLQFMWKADVVESWIADKETHV--RSEEFGRDLSTVQ
TLLTKQETFDAG--------------LHAFEHEGIQNITSLKEMLVDSGHDQTPSIQKRH
ADVIARWQKLLADSDARKQRLLRMQDQFRQIEELYLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSIEEIRALREAHAQFQASLSSAEADFEALAALDRQIKSFNVGPNPYTWFT
MEA-LEDTWRNLQKIIKERDVEL----------------------------AKEAQRQEE
--------NDKLRKEFAKHANAFHQWLAETRTSMMEG-----------------------
----SGSLEQQLEATKRKTQEVRAR-----------------------------------
------------------------------------------RQDLKKIEDLGAILEEHL
ILDNRYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNQSGVSEDALK------------------EFS
MMFKHFDKDKSGR---------------LNHQEFKSC-----------------------
-------LRAL---------------------GYDLPMV---------------------
EEGQPDPEFENILDVVDPN-----RDG----------YVSLQEYMA--------------
-FMISKET----------------------ENVQSSEEIENAFRAITAAD---RP-----
---------YVTKEELYANLTKEMAD---YCVA-----RMKPYVDPKTERPITGALDYIE
FTRTLFQN---------------------------------------
>gi|119910515|ref|XP_617751.3|	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MRIWPSGGAGGAEPSRLGRAGPRTPTGR
AVGHGEQRGQRHRRPRGQASSPPMAQVPGEVDNMEGLPAPNNNNLSARWDSPDRGWEREQ
PAASTAAASLFECSR--IKALADEREAVQKKTFTKWVNSH--------------------
---------LARVGCHIG----DLYTDLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHS--
------------------------------LENVDKALQFLKEQRVHLENVGSHDIVDGN
HRLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNI-----QN
FTTSWRD-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------GLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHL
GLARLLDPEDVN------------------------------------------------
---------------------------------------------------MEAPDEKSI
ITYVVSFYHYFS----KMKALAVEGKRIGKV--LDQVLEV----GKIIERYEELAT----
-------------------ELLAWIHRTVGLISNQKFANSLSGVQQQLQAFTAY------
------CTLEKPVKFQEKGN-------------------------------------LEV
LLFSIQSKLRACNRR------------LYVPREGCGIW-----------DIDKAWGQLE-
----KAEHEREAALRAELIR---------------------QEKLELLAQR---------
-------------FDHKVAMRESWLNENQRLVSQ-DNFGYELPAVEAAMKKHEAIEADIA
AYEERVQ-----GVAELAQALATEGYYDARRVAAQRDSVLRQWALLTGLVGARRTRLEQN
LALQKVFQEMVYMVDWMEEMQAQLLS------------RECGQHLVEAEDLLQK------
---------------HGLLEGD-IAAQSERVEALNAAALRFS-----Q-----PCDPQVI
CNRVNHVHGCLAELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGA
AGATGAAG---GAHDLSSTARLLAQHKILQGELGGRRALLQQALRRGEELAAAGGAVGPG
AETVHLAGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRL
AAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVGGLRRQLA--------TLGGASGAGP
LVV---------------------------------------------------------
----------------------------------------------------ALQVRVVE
AEQL--------------------------------------------------------
-------------------------------------FAEVTEVAALRRQWLRDALAVYR
MFGEVHACELWIGEKEQWLLAMR-VPNSLDDVEVVQHRFESLDQEMNSL-MGRVLDVN--
------------------------------------HTVQELVEGG--HPSSDEVRSC--
------------------------------------------------------------
---QDHLNSRWNRIVELVEQRKEEVSAVLLVENHVLEVAEVRTQVREKRRAVESAPRAGG
------ALQWRLSGLEAALQALEPRQAALLEE--AALLAVRFP-AQAARLHQGAEELGAE
WGALASAAQACGEAVAAAGRLQRFLHDLDAFLDWLVRAQETAGGGEG-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------PLPRSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAG
DGAELGPGLALDEWLPHLELGWHKLLGLWEARREALVQAHVYQLFLRDLRQARAVLRNQE
MALSG--QELPGTVESVEEALKRHRDFLTTMELNQQKMQLAVQAAEGLLRQGNAYGEQAQ
EAVTRLLEKSQENQLRAHQWMQKLHDQLGLQHFLRDCHELDGWIHEKMLMARDGTREDGH
KLH------------KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAA--SVRK
KLGEIRQCWAELEST-TQAKARQLFEASKADQLVQSFAELDKKLL---------------
----HMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWYREVGELQAQTAAL-PLEPAS
KELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQ-VAHDLEDELAWVQERLPLAMQT
ERGSGLQAVQQ-------------YIKKNQGLRREIQAHGPRLEEVLERAGALA---SLR
SPEAEAVRRGQEQLQGAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGEQELLMM
SEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQV
DRLYVALKELGEERRVGLEQQYWLYQLSRQVDELEHWIAEKEVVA--GSPELGQDFEHVT
VLQEKFSEFASE--------------TGTAGRERLAAVNQMVDELIECGHTAAATMAEWK
DGLNEAWAELLELMGTRAQLLAASRELHK--------FFSDARELQGQIEEK----RRRL
PRLTTPPEPRP--SASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIAS
REQEVLQGWKELLAACEDARLHVSSTADALRFHNQARDLLSWMDGIAGQIGAADKPRDVS
SVEVLMNYHQGLKTELEARMPELTACQELGRSLLLNK-----------------------
-SAMADEIQAQLDKLGTRKEEVSDKWDRHWEWL---------------------------
--------------------QQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVE
QLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRKFFGDPTELAAKA
APLLRPGGSERGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPEVPGRVEP
TAQPAAPEDAAETPGAPAVVAAEQVRPRPERQESADRAE------------------ELP
RRRRPERQESADQSEEAARRRRPERQESTEHEVAHSLTLGRYEQMERRRERRERRLERQE
SSEQEMPIRGDLAKGKATLADIVEQLQEKEA-GPGLPVG-PSLPQPRELPPGRLPNGLEP
PERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHE
GFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGFYKDAKGPASGGTHGG---EPLLSLH
KATSEVASDYKKKKHVFKLQTQDGSE---FLLQAKDEEEMNGWLEAV-AASVGEHAEIAR
WGQTQPTTSSTDEGNPKREAGERRASGRRK-----------------
>gi|110227609|ref|NP_001036003.	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPSGVKVLE-----TAEDIQERRQQVLDRYHRFK
ELSSLRRQKLEDSYR--FQFFQRDADELGK-----WIQEK--------------------
---------LQIASDENYKDPSNLQGKLQKHQAFEAEVQANSGAIVKLDETGNQMINEGH
FASETIRTRLQELHRLWELLLEKMREKGVKLLQAQKLVQFLRECEDVMDWINDKEAIVTS
EELGQDLEHVEVLQKKFE--EFQTDLAAHEERVNEVNQFAGKLIQEQHPEEELIKSKQDE
VNASWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKGLAQQRQGKLFGAAEVQRFNRDVDETISW-IKEKGQ
----LMASDDFG------------------------------------------------
---------------------------------------------------RDLASVQAL
LRKHEGLERDLAAFHHKVKALCAEADRLQQSH-PINASQIQVKREELIANWEQIRTLAAE
RHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDA
HEDSFRSADESGQALLAAGHYASDEVKEK----------------------------LTI
LSDERSALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA
LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMDDVATRRDALLSRRNALHERAMK
RRAQLADSFHLQQFFRDSDELKSWVNEKMKTATD-EAY-KDPSNLQGKVQKHQAFEAELS
ANQSRID-----ALEKAGQKLIDVNHYASDEVAARMNEVISLWKKLLEATELKGIKLREA
NQQQQFNRNVEDIELWLYEVEGHLAS------------DDYGKDLTSVQNLQKK------
---------------HALLEAD-VAAHQDPIDGITIQARQFQ-----DAGHF---DADNI
KKKQEALVARYEALKDPMVARKQKLADSLRLQQLFRDIEDEETWIREKEPIAASTNRGK-
--------------DLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEG------
--HFAAEDVKIKLNELNQKWDSLKAKASQRRQDLEDSLQAQQYFADANEAQSWMREKEPI
VGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVA-PTDDETGKEL
VLALYDYQEKSPREVTMKKGDILTLLNSTNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKKL--DPAQSASRENLLEEQGSIALRQEQ
IDNQTLITKEVGSVS---------------------------------------------
----------------------------LRMKQVEELYHSLLELGEKRKGMLEKSCKKFM
LFREANELQQWINEKEAALTNEE-VGADLEQVEVLQKKFDDFQKDLKAN-ESRLKDIN--
------------------------------------KVANDLESEGLMAEEVQAVEHQ--
----------------------------EVYGMMP-RDETDSKTVSPWKSARMMVHTVAT
FNSIKELNERWRSLQQLAEERSQLLGSADEVQRFHRDADETKEWIEEKNQALNTDNY-GH
DLASVQALQRNDEGFERDLAALGDKVNSLGET--AQRLIQSHP-ELAEDLQEKCTELNQA
WSSLGKRADQRKEKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAR
GHY-ASP--EIKEKLDILDQERTDLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAARE
AFLNT--EDKGDSLDSVEALIKKHEDFDKAINVQEEKIAVLQSFADQLIAADHYAKGVIA
NRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPT
NIQLS-------KLLSKHQKHQAFEAELHANADRIRGVIEMGNPLIERGACAGSEDAVKA
RLAALADQWEFLVQK-SSEKSQKLKEANKQQNFNTGIKDFDFWLS---------------
----EVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFD
TSQVKDKRETINGRFQRIKSMAAARRAKLNESHRLHQ-FFRDMDDEESWIKEKKLLVSSE
DYGRDLTGVQN-------------LRKKHKRLEAELAAHEPAIQGVLDTGKKLS---DDN
TIGKEEIQQRLAQFVDHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVA
SEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCANGEDLIKKNNHHVENITAKMKGL
KGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL--KTDDYGRDLSSVQ
TLLTKQETFDAG--------------LQAFQQEGIANITALKDQLLAAKHIQSKAIEVRH
ASLMKRWNQLLANSAARKKKLLEAQEHFRKVEDLFLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFT
MEA-LEETWRNLQKIIKERELEL----------------------------QKEQRRQEE
--------NDKLRQEFAQHANAFHQWIQETRTYLLDG---------------------SC
MVEESGTLESQLEATKRKHQEIRAM-----------------------------------
------------------------------------------RSQLKKIEDLGAAMEEAL
ILDNKYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNTTGVTEEALK------------------EFS
MMFKHFDKDKSGR---------------LNHQEFKSC-----------------------
-------LRSL---------------------GYDLPMV---------------------
EEGEPDPEFESILDTVDPN-----RDG----------HVSLQEYMA--------------
-FMISRET----------------------ENVKSSEEIESAFRALSSER---KP-----
---------YVTKEELYQNLTREQAD---YCIS-----HMKPYMDGK-GRELPSAYDYIE
FTRSLFVN---------------------------------------
>gi|157108966|ref|XP_001650465.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MEQFTPKEVKILE-----SAEDIQERREQVLNRYNEFK
VETRHKREKLEDSRR--FQYFKRDSDELES-----WIHEK--------------------
---------LQAASEESYRDPTNLQAKIQKHQAFEAEVSAHSNAIVVLDNTGQEMINQHH
FASDTIQRRLDELHRLWELLLSRLAEKGMKLQQALVLVQFLRHCEEVMFWIKDKEAFVTA
DEFGQDLEHVEVLQRKFD--EFQKDMASQEYRVTEVNELADKLLSNGHPERETITRKKEE
LNEAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKQLAILRQEKLFGAHEIQRFNRDADETVAW-IAEKDV
----VLSSDDYG------------------------------------------------
---------------------------------------------------RDLASVQAL
QRKHEGVERDLAALEDKVATLGAEAGRLCSIH-ADHSDQIREKQAEIAAYWQSLTAKAKE
RKQKLDESYFLHRFLADFRDLVSWINGMKAIISADELAKDVAGAEALLERHQEHKGEIDA
RGDSFKVTTEAGRQLLEREHYAAAEVQEK----------------------------LAA
LESDKSSLLALWEERRILYEQCMDLQLFYRDTEQADTWMAKQEAFLANEDLGDSLDSVEA
LIKKHEDFEKSLAAQEEKIKALDVFATKLIDGQHYAADDVAQRRSMLLARRSALLEKSSV
RRQLLEDSSALQQFERDCDETKGWISEKLKFATD-DSY-LDPTNLNGKVQKHTNFEHELT
ANKSRIE-----DITTNGQNLVEKGHYGADQINSRMQEIVTLWESLVQSSDKKGCKLQEA
SQQQQFNRTVEDIELWLSEVEGQLMS------------EDYGKDLTSVQNLQKK------
---------------HGLLEAD-VMAHQDRIEGIKVAANKFV-----ESGHF---DADNI
RNKESALSKRYGALATPMAERKQRLLDSLQVQQLFRDLEDEAAWIREKEPVAASTNRGR-
--------------DLIGVQNLIKKHQAVLAEINNHENRVAGVIANGEQMLTEQ------
--PFATEDIKLRLDAVKDQWNSLKEKANQRKQDLEDSLQAHQYFADANEAESWMREKEPI
VSNQDYGKDEDSSEALLKKHEALVSDLEAFGNTIQALQEQAKNCRQQET-PVVDITGKEC
VMALYDYTEKSPREVSMKKGDVLTLLNSNNK-----------------------------
------------DWWKVEVNDRQGFVPAAYIKKI--DPGLSASQQNLV-DGHSIAKRQAQ
INSQ--------------------------------------------------------
-------------------------------------YDNLLALARERQNKLNETVKAYV
LVREAADLSAWIRDKESHAQIKD-VGEDLEEVEVMQKKFDDFNDDLKAN-EVRLAKLN--
------------------------------------EIAVQLTSLG-QTEAALKIKTQ--
------------------------------------------------------------
---IQTLNEEWTVLQNITQERASQLGSAHEVQRFHRDVDETKDWIGEKDTALTNDDL-GK
DLRGVQTLQRKHEGLERDLAALRDKIRQLDET--ANRLMQSHP-ETAEQTYAKQKEINEE
WQQVVAKTQQRKEKLLDSYDLQRFLSDYRDLMAWISSMMGLVTSEE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LANDVTGAEALIERHQEHRTEVDARAGTFAAFDQFGAELLQA
NHY-ASP--EIQEKIENLAKAREDLERAWTARRLQLDQNLDLQLYLRDCEQAENWMSARE
AFLNA--EEVDSKGDNVEALIKKHEDFDKAINGHEEKIAALQVLADQLIAQEHYAGKLID
DKRADVLDRWRHLKEDLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQLATEESYKDPA
NIQ------------SKHQKHQAFEAELAANADRIQSVLAMGSNLIDKNQCSGSEDAVQK
RLTQIADQWEYLTQK-TTEKSLKLKEANKQRTYIAAVKDLDFWLG---------------
----EVESLLTSEDAGKDLASVQNLMKKHQLVEADIHAHEDRIKDMNAQADSLVESGQFD
SAGIQEKRQSINERYERICNLAAHRQARLNEANTLHQ-FFRDIADEESWIKEKKLLVGSD
DYGRDLTGVQN-------------LKKKHKRLEAELASHEPAIQAVQEAGEKLM---DVS
NLGVPEIEQRLKALNQAWAELKSLAATRGQKLDESLIYQQFLAKVEEEEAWITEKQQLLS
VEDYGDSMAAVQGLLKKHDAFETDFAAHRDRCADIHDNGQTLVTNNNHHAESISQRCTQL
DKKLENLQALATRRKSALLDNFAYLQFMWKADVVESWIADKENHV--KSEEFGRDLSTVQ
TLLTKQETFDAG--------------LSAFEHEGIHNITALKDQLINANHAQSAAILKRH
EDVLTRWQKLRADSEARKYRLLAMQEQFRQIEDLYLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSIEEIKALREAHAQFQASLSSAQYDFQALADLDRKIKSFNVGPNPYTWFT
MEA-LEDTWRNLQKIIEERDAEL----------------------------AKEVHRQEE
--------NDKLRKEFAKHANLFHQWLTETRTSLMDG-----------------------
----SGSLEEQFEALCHKANEIRAR-----------------------------------
------------------------------------------RGDLKKIEELGATLEEHL
ILDNRYT--EHSTVGLAQQWDQLDQLAM--------------------------------
------------------------------------------RMQHNLR-----------
----------------------QQIQARNQSGVSEDSLK------------------EFS
MMFKHFDKDKSGK---------------LNHQEFKSC-----------------------
-------LRAL---------------------GYDLPMV---------------------
EEGQPDPEFEEILNVVDPN-----RDG----------HVSLQEYIA--------------
-FMISKET----------------------ENVQSYEEIENAFRAITASD---RP-----
---------YVTKDELYSNLTKDMAD---YCVQ-----RMKPFNDPKTGHPITGALDYVE
FTRTLFQN---------------------------------------
>gi|31218879|ref|XP_316724.1|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MEQFTPKEVRILE-----SAEDIQERRDQVLNRYSEFK
LETRQKREKLEDSRR--FQYFKRDSDELES-----WINEK--------------------
---------LQAASEESYRDPTNLQAKIQKHQAFEAEVSAHSNAIVVLDNTGQEMINQGH
FASETIQRRLEELQRLWELLLSRLAEKGMKLQQALVLVQFLRHCEEVMFWIKDKEAFVTA
DEFGQDLEHVEVLQRKFD--EFQKDMASQEYRVTEVNELADKLLFGGHPERETITRKKEE
LNEAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKQLAILRQEKLFGAHEIQRFNRDADETVAW-IAEKDV
----VLSSDDYG------------------------------------------------
---------------------------------------------------RDLASVQAL
QRKHEGVERDLAALEDKVAALGTEAGRLCSIH-ADHSEQIREKQAEIAAYWQSLTAKAKE
RKQKLDESYFLHRFLADFRDLVSWINGMKAIISADELAKDVAGAEALLERHQEHKGEIDA
RVDSFKLTTEAGRQLLEREHYAAAEVQEK----------------------------LAA
LENDKSSLLVLWEDRRILYEQCMDLQLFYRDTEQADTWMAKQEAFLANEDLGDSLDSVEA
LIKKHEDFEKSLAAQEEKIKALDVFATKLIDGQHYAADDVAQRRAMLLARRSALQEKSSV
RQKLLEDSNALQQFERDCDETKGWISEKLKFATD-DSY-LDPTNLNGKVQKHTNFEHELT
ANKSRIE-----DITATGQELATKEHYAADKVNARMQEIVTLWESLVRASDKKGCKLQEA
SQQQQFNRTVEDIELWLSEVEGQLLS------------EDYGKDLTSVQNLQKK------
---------------QALLEAD-VMAHQDRIEGIKVAANKFV-----ESGHF---DADNI
RAKEAALSKRYAALAEPMSIRKQRLLDSLQVQQLFRDLEDEAAWIREKEPVAASTNRGR-
--------------DLIGVQNLIKKHQAVLAEINNHESRCAGVISNGEQMLNEQ------
--PTASEEIKLRLDALKDQWNSLKEKSNQRKQDLEDSLQAHQYFADANEAESWMREKEPI
VSNQDYGKDEDSSEALLKKHEALVSDLEAFGNTIQALQEQAKNCRQQET-PVVDITGKEC
VMALYDYTEKSPREVSMKKNDVLTLLNSNNK-----------------------------
------------DWWKVEVNDRQGFVPAAYIKKI--DPGLSASQQNLI-DGHSIAKRQTQ
INSQ--------------------------------------------------------
-------------------------------------YDNLLALARERQNKLNETVKAYV
LVREAADLAAWIKDKESHAQIKD-VGEDLEEVEVLQKKFDDFNDDLKAN-EVRLAKLN--
------------------------------------EIAIQLTSLG-QTEAALKIKTQ--
------------------------------------------------------------
---IQTLNEEWATLQTITQERASQLGSAHEVQRFHRDVDETKDWIAEKENALNNDEL-GK
DLRGVQTLQRKHEGLERDLAALQDKIRQLDET--ANRLMQSHP-DTAEQTYAKQKEINEE
WQQVVTKAQQRKEKLLDSYDLQRFLSDYRDLSAWISSMMGLVTSEE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LANDVTGAEALIERHQEHRTEVDARAGTFSAFEQFGNELLQA
NHY-AAP--EIQEKIENLNKAREELERAWTARRLQLDQNLDLQLYLRDCEQAENWMSARE
AFLNA--EEVDSKGDNVEALIKKHEDFDKAINGHEEKIGALQVLADQLIAQEHYAGRLID
AKRQEVLDRWRHLKEDLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQLATEESYKDPA
NIQ------------SKHQKHQAFEAELAANADRISSVLAMGSNLIDRNQCSGSEEAVQK
RLTQIADQWEYLTQK-TTEKSLKLKEANKQRTYIAAVKDLDFWLG---------------
----EVESLLTSEDAGKDLASVQNLMKKHQLVEADIHAHEDRIKDMNSQADSLVESGQFD
SAGIQEKRQSINERYERIRNLAAHRQARLNEANTLHQ-FFRDIADEESWIKEKKLLVGSD
DYGRDLTGVQN-------------LKKKHKRLEAELASHEPAIQAVQEAGEKLM---DVS
NLGVPEIEQRLKALNQAWTELKGLAATRGQKLDESLIYQQFLAKVEEEEAWITEKQQLLS
VEDYGDSMAAVQGLMKKHDAFETDFAVHRDRCSDIRDHGQTLVTNNNHHGDSISQRCVQL
DKKLENLQALATRRKTALMDNFAYLQFMWKADVVESWIADKENHV--KSEEFGRDLSTVQ
TLLTKQETFDAG--------------LSAFEHEGIHNITALKDQLINANHAQSAAILKRH
EDVLTRWQKLRADSEARKYRLLNMQDQFRQIEDLYLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSIEEIKALREAHAAFQASLSSAQVDFQALAALDQKIKSFNVGPNPYTWFT
MEA-LEDTWRNLQKIIEERDAEL----------------------------AKEVHRQEE
--------NDKLRKEFAKHANLFHQWLTETRTSLMDG-----------------------
----SGSLEEQFEALCHKANEIRAR-----------------------------------
------------------------------------------RGDLKKIEELGATLEEHL
ILDNRYT--EHSTVGLAQQWDQLDQLAM--------------------------------
------------------------------------------RMQHNLK-----------
----------------------QQIQARNQSGVSEDSLK------------------EFS
MMFKHFDKDKSGK---------------LNHQEFKSC-----------------------
-------LRAL---------------------GYDLPMV---------------------
EEGQPDPEFEEILNVVDPN-----RDG----------QVSLQEYIA--------------
-FMISKET----------------------ENVQSFEEIENAFRAITASDPRPRP-----
---------YVTKEELYSNLTKDMAD---YCVQ-----RMKPYNDPKTGHPITGALDYVE
FTRTLFQN---------------------------------------
>gi|47211130|emb|CAF90368.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDTTGVKVLE-----TAEDIQDRRQQVLDRYRRFK
ELSVMRRQKLEDSYR--FQCFRRDAEELEK-----WIQEK--------------------
---------LQIASDENYKDPSNLQGKLQKHQAFEAEVQANAGTIIKLDETGNLMISEGH
FASETIRSRLEELHRLWDLLLQKTKEKGLRLLQAQKLVQYLRECEDALDWISDKEAMATS
EELGQDLEHVELLQKKFE--EFQTDLAAHEERVNEVNQLAAKLIQESHPEVELIVRKQDE
VNAAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKGLAQQRQGRLFGAAEVQRFNRDVDETISW-IKEKEQ
----LMASDDFG------------------------------------------------
---------------------------------------------------RDLASVQAL
LRKHEGLERDLAALEDKVNTLGGDAGRLQETH-PQNASQILLKKDELVANWEQIRTLAAE
RHARLDDSYRLQRFTADFRDLTSWVTEMQALIKADELANDVAGAEALLDRHQEHKGEIDA
HEDSFRSTDEAGQALVNTGHYASEEVKEKVGLPPDCPQTAGVVFSCVSRVCVCVRVQLGI
LSEEKEALLNLWEVRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA
LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKEDVATRRDALLSRRNALHERAQS
RRAALEDSFHLQQFFRDSDELKSWINEKMKTATD-EAY-KDPSNLQGKVQKHQAFEAELS
ANQSRID-----ALQKSGQDLLERKHYASSEVARRMEEVSSQWKKLLEATELKASRGQPA
AAVQQ-------------ERGGHRAV------------AVRGGGPPGLRRLRQGPDQRPE
PAEEARAAGGRRGCSPGLLRVNSLISSQDRIDGISIQARQFQ-----EAGHF---DADNI
RRKQEALALRYEALRQPMATRKQKLSDSLRLQQLFRDVEDEETWIREKEPIAASTNRGK-
--------------DLIGVQNLLKKHQALQAEIVGHEPRIKAVTQKGETMVEEG------
--HFAGEDVKVKLTELHGRWDTLKLKASQRKQDLEDSLQAQQYFADANEAESWMREKEPI
VGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQGLKEQAQSCRQQVA-PTDDETGKEL
VLALYDYQEKSPREVTMKKGDILTLLNSTNKVERWLACSRAAGSAPPWWRLQVVGLAEPS
SLHPMTCGLSWQDWWKVEVNDRQGFVPAAYVKKL--DPNQSSSRENLLEEHGSIALRQDQ
IENQ-LVTKEACSVS---------------------------------------------
----------------------------VRMKQVEELYANLLELGEKRKDMLEKSCKKFM
LFREANELQQWIHEKEGTLTNEE-VGSDLEQVEVLQKKFDDFQKDLKAN-ESRLRDIN--
------------------------------------KVAAELESEGLMAEETPMVQAQVP
GVPPGARLAFRRQHQPHPLFFLFLQQQQELLGAAPGKDEADSKTASPWKNVRLAVQTTAN
FNTIKELNNRWRSLQQLAEDRSHMLGSA------TRDADETKEWIEEKNQALNTDNY-GH
DLASVQALQRKHEGFERDLAALGDKVNSLGET--AERLIQSHP-EAVEDIKEKCSELNTA
WSSLVGRADQRKDKLANSHDLQRFLSDFRDLMSWINGIRGLVSSEE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLVR
GHY-ASP--EIQQKLEALEQERTHLEKAWVQRRMMLDQCLELQLFSRDCEQAENWMAARE
AFLAS--DDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQSFADQLIGADHYAKAEIH
SRCREVLDR------------------ASIRSIRRS------------RQSCTLTQTHPR
GHR-----------------H--------------------GNALIQRGACAGSEDAVKT
RLAALDEQWQFLVNK-SAEKSQKLKEANKQQNFNTGIKDFDFWLS---------------
----EVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMASDAFD
TSQVKDKRSGVNARFAKIKSMAATRRARLNESHRLHQ-FFRDLDDEESWIKEKKLLVSSE
DYGRDLTGVQN-------------LRKKHKRLEAELGAHEPAIQSVLDTGKKLS---DDN
TIGQEEIQQRLAQFVDHWKELKDLSGARGQRLEESLEYQQFVANVEEEEAWINEKLNLVA
SEDYGDTLAAVQGLLKKHEAFETDFTVHRDRVGDVCSNGGELIKKNNHHVNNISAKMAAL
GEKVAELDRAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL--KTDDYGRDLSSVQ
TLLTKQETFDAG--------------LQAFQQEGISNISALKEQLLAAQHVQAKAIQARH
AALIKRWTQLLSNSAARKKKLLEAQEHFRKVEDLFLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSLEEIRALREAHEAFRSSLSSAQADFDQLAELDKQIKSYLVVSNPYTWFT
MEA-LEETWRNLQKIIKERELEL----------------------------QKEQRRQEE
--------NDKLRQEFAQHANAFHQWLQETRTYLLDGFLGLLGPGPGAVTHLSVCVGRSC
MVEESGTLESQLEATKRKHQEIRAM-----------------------------------
------------------------------------------RSQLKKIEDLGAAMEEAL
ILDNKYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNTTGVTEEALK------------------EFS
MMFKHFDKEKSGR---------------LNHQEFKSC-----------------------
-------LRSL---------------------GYDLPMV---------------------
EEGEPDPEFQAILDTVDPN-----RERERVPAGVHGLHDQPRDGER--------------
-QVQRGDR----------------------ERLPGPERREQALRD--QGGAVPEPDQGAG
RLLPVPHEALPGRQGPRAALGLRLRGVHPLALR-----QLTNREPGGVPPPPPRVVDVA-
WLQDLGVVC--------------------------------------
>gi|73968102|ref|XP_537823.2|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MNKLENMVCGN
ALMKQYQVQFWKMILLIKEDYFPRKRGARVAATTRCGANGEARGRGGASVLSSPQPGAAT
ALTPREPTPHSSIMLSSFRKRRVQKMDPSGVKVLE-----TAEDIQERRQQVLDRYHRFK
ELSTLRRQKLEDSYR--FQFFQRDAEELEK-----WIQEK--------------------
---------LQIASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGH
FASETIRTRLMELHRQWELLLEKMREKGVKLLQAQKLVQYLRECEDVMDWINDKEAIVTS
EELGQDLEHVEVLQKKFE--EFQTDMAAHEERVNEVNQFAAKLIQEQHPEEETIKTKQDE
VNAAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKGLALQRQGKLFGAAEVQRFNRDVDETISW-IKEKEQ
----LMASDDFG------------------------------------------------
---------------------------------------------------RDLASVQAL
LRKHEGLERDLAALEDKVKALCAEADRLQQSH-PLSAAQIQVKREELIANWEQIRTLAAE
RHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDA
HEDSFKSADESGQALLAAGHYASDEVREK----------------------------LSI
LAEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA
LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMC
RRAQLADSFHLQQFFRDSDELKSWVNEKMKTATD-EAY-KDPSNLQGKVQKHQAFEAELS
ANQSRID-----ALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKLREA
NQQQQFNRNVEDIELWLYEVEGHLAS------------DDYGKDLTNVQNLQKK------
---------------HALLEAD-VAAHQDRIDGITIQARQFQ-----DAGHF---DAENI
KKKQEALVARYEALKEPMIARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGK-
--------------DLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEG------
--HFAAEDVKAKLSELNQKWESLKSKASQRRQDLEDSLQAQQYFADANEAESWMREKEPI
VGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALRDQAQSCRQQVA-PMDDETGKEL
VLALYDYQEKSPREVTMKKGDILTLLNSTNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKKL--DPAQSASRENLLEEQGSIAVRQEQ
IDHQTRITKEAGSVS---------------------------------------------
----------------------------LRMKQVEELYHSLLELGEKRKGMLEKSCKRFM
LFREANELQQWINEKEAALTSEE-VGADLEQVEVLQKKFDDFQKDLKAN-ESRLKDIN--
------------------------------------KVAEDLESEGLMAEEVQAVQQQ--
----------------------------EVYGMMP-RDDTDSKTASPWKSARLMVHTVAT
FNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNY-GH
DLASVQALQRKHEGFERDLAALGDKVNSLGET--AERLIQSHP-ESAEDLQEKCTELDQA
WSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAH
GHY-ASP--EVKEKLDILDRERAGLEKAWAQRRMMLDQCLELQLFHRDCEQAENWMAARE
AFLNT--EDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQSFADQLIAAGHYAKGDIC
SRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPT
NIQLS-------KLLSKHQKHQAFEAELHANADRIRGVIDTGNSLIERGACAGSEDAVKA
RLAALADQWQFLVQK-SAEKSQKLKEANKQQNFNTGIKDFDFWLS---------------
----EVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFD
TSQVKDKRDTINGRFQKIKNMAASRRARLNESHRLHQ-FFRDMDDEESWIKEKKLLVSSE
DYGRDLTGVQN-------------LRKKHKRLEAELAAHEPAIQGVLDTGKKLS---DDN
TIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVA
SEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCSNGQDLIKKNNHHEENISSKMKGL
NGKVSDLEKAAAQRKAKLEENSAFLQFNWKADVVESWIGEKENSL--KTDDYGRDLSSVQ
TLLTKQETFDAG--------------LQAFQQEGIANITALKDQLLAAKHIQSKAIEARH
ASLMKRWSQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSLEEIRALREAHDAFRSSLSSAQADFSQLAELDRQIKSFRVASNPYTWFT
MEA-LEETWRNLQKIIKERELEL----------------------------QKEQRRQEE
--------NDKLRQEFAQHANAFHQWIQETRTYLLDG---------------------SC
MVEESGTLESQLEATKRKHQEIRAM-----------------------------------
------------------------------------------RSQLKKIEDLGAAMEEAL
ILDNKYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNTTGVTEEALK------------------EFS
MMFKHFDKDKSGR---------------LNHQEFKSC-----------------------
-------LRSL---------------------GYDLPMV---------------------
EEGEPDPEFEAILDTVDPN-----RDG----------HVSLQEYMA--------------
-FMISRET----------------------ENVKSSEEIESAFRALSSEG---KP-----
---------YVTKEELYQNLTREQAD---YCVS-----HMKPYVDGK-GRELPTAFDYVE
FTRSLFVN---------------------------------------
>gi|156553897|ref|XP_001601352.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------MDQQITPKEVKILE-----NPEDIQERREQVLGRYANFK
SEARSKRDKLEDSRR--FQYFKRDADELEG-----WIYEK--------------------
---------LQAASDESYKDPTNLQAKIQKHQAFEAEVAAHSNAIVLLDNTGSEMIAQHH
FASDIIRKRLEELHRLWELLLNRLADKGLKLQQALVLVQFIRHCDEVMFWIHDKEVFVTT
DEFGQDLEHVEVLQRKFD--EFQKDMTSQEYRVTEVNELADKLLLDAHPERDTILRRKEE
LNESWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKQLAILRQEKLFGAHEIQRFNRDADETMAW-IGEKDA
----VLSSDDFG------------------------------------------------
---------------------------------------------------RDLASVQLL
QRTHENIERDLAALEDKVATLSTEADRLAGIHQAEHSQQIQSKRAEILQSWESLTAKAKE
RRFKLDESYYLHRFLADYRDLVSWMNNMRAIISADELAKDVAGAEALLERHQEHKGEIDA
RADSFDSTGLAGSKLLERQHYAASEVAIK----------------------------LES
LAADKASLLELWEKRRILYEQCMDLQLFYRDTEQADAWMAKQEAFLANEDLGDSLDSVEA
LIKKHEDFDKSLAAQEEKIKALDEFASKLIEGEHYAADEVAQRRQALLQRRSALLEKSAL
RRRALEDAYKLQQFERDCDETKGWVNEKLKFATD-DSY-LDPTNLNGKLQKHQNFEQELQ
ANKTRMQ-----EMVAQGQELIEAEHYARERIQSRIKEIVELWESLTEATEKKGNKLQEA
AQQQQFNRTVEDVELWLSEVEGQLLS------------EDYGKDLTSVQNLQKK------
---------------HALLEAD-VASHQERIASIAQAAEQFV-----AGGHF---DADNI
RQKQQQLQGRYSALEQPMQMRKQRLLDSLQVQQLFRDVEDEEAWIREKEPVAASTNRGR-
--------------DLIGVQNLQKKHQAVLAEINNHEPRVAAVCAAGSRMLSDG------
--HFAAEEISQRLASLDEHWGQLKEKARQRKNDLDDSLQAHQYFADANEAESWMKEKRPI
VMNADYGKDEDSSEALLKKHEALVSDLEAFASTIAALKEQAAACRQQET-PAVDVAGKEC
VVALYDYTEKSPREVSMKKGDTLTLLNSSNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKRVEPDAGLSASQQNLAREQGSIAARQAQ
IEAQ--------------------------------------------------------
-------------------------------------YEDLLRLARERQNKLNETAKAYV
LVREAAELATWIKGKENHAQVQD-VGEDLEQVEVMQKKFDDFRADLKAN-EVRLAEMN--
------------------------------------EIAVQLMSVG-QTEAALKIQTQ--
------------------------------------------------------------
---IQELNEKWTSLQTLTAERASQLDSAHEVQRFHRDVDDTKDWIREKDAALNNDDL-GK
DLRSVQTLLRKHEGLERDLAALGDKIKQLDET--ANRLMQSHP-DTAEQTYTKQKEINEE
WTQLTAKADSRKKKLLDSYDLQRYLSDYRDLMAWINSMMGLVASEE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LANDVTGAEALLERHQEHRMEIDARVGTFQAFELFGQQLLQS
NHY-ASV--EIQEKLESMNEARQELEKAWIQRRMQLDQNLELQLFCRDCEQAENWMSARE
AFLSSSSADALDSGDNVEALIKKHEDFDKAINGHEEKIAALQTLADQLIAAEHYAARPID
ERRCQVLDRWRHLKDALIEKRSRLGESQTLQQFSRDADEMENWIAEKLQLATEENYKDPA
NIQ------------SKHQKHQAFEAELAANAERISSVLAMGGNLIEKHQCAGSEDAVQK
RLASIADQWEYLTHK-TTEKSMKLKEANKQRTYIAAVKDLDFWLG---------------
----EVESLLTSEDAGKDLASVQNLMKKHQLVEADINAHEERIKDMNAQADSLIESGQFE
AAGIQEKRQSINERYERVRNLAAHRQARLNEANTLHQ-FFRDIADEESWIKEKKLLVGSD
DYGRDLTGVQN-------------LKKKHKRLEAELGSHEPAIQAVQEAGEKLM---DVS
NLGVPEIEQRLKLLEQAWSELKQLAATRGQKLDESLAYQQFLAKVEEEEAWIAEKQQLLS
LEDYGDTMAAVQGLLKKHDAFETDFAAHGERCREIREAGEGLIAAGNHRAEAIEQRCQQL
GAKLEQLGALAARRKTRLNDNSAYLQFMWKADVVESWIADKETHV--RSEEFGRDLSSVQ
TLLTKQETFDAG--------------LHAFEHEGIQNITSLKEMLIEAGHEQSPAIHKRH
ADVIARWQKLLADSQARKQRLLQMQEQFRQIEELYLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSIEEIRALREAHAQFQASLSSAEADFQALGALDRQIKNFNVGPNPYTWFT
MEA-LEDTWRNLQKIIKERDVEL----------------------------AKEAQRQEE
--------NDKLRKEFAKHANAFHQWLADTRTSMMEG-----------------------
----SGSLEQQLEATKRKTQEVRAR-----------------------------------
------------------------------------------RQDLKKIEDLGAILEEHL
ILDNRYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNQSGVSEGALK------------------EFS
MMFKHYDKDKSGR---------------LNHQEFKSC-----------------------
-------LRAL---------------------GYDLPMV---------------------
EEGQPDPEFENILDIVDPN-----RDG----------FVSLQDHMA--------------
-FMISKET----------------------ENVQSSQEIENAFRAITAAD---RP-----
---------YVTKEELYANLTKEMAD---YCVA-----RMKPYVDPKTERPITGALDYIE
FTHTLFQN---------------------------------------
>gi|148596963|ref|NP_001091958.	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDISGVKVLE-----TADDIQERRQQVLDRYRRFK
ELSVVRRQKLEDSYR--FQFFRRDADELEK-----WIQEK--------------------
---------LQIASDENYKDPSNLQGKLQKHQAFEAEVQANAEAIIKLDETGNLMISEGH
FASETIRTRLEELHRLWDLLLQKTKEKGIRLLQAQKLVQYLRECEDALDWISDKEAIVTS
EELGQDLEHVEVLRKKFE--EFQTDLAAHEERVNEVNQAAGKLTQENHPEAELILKKQEE
VNSAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKGLAQQRQGKLFGAAEVQRFNRDVDETISW-IKEKEQ
----LMASDDFG------------------------------------------------
---------------------------------------------------RDLASVQAL
LRKHEGLERDLAALNDKVNTLGGEADRLQQTH-PQNATQIHLKRDELITNWEQIQTLATE
RHARLNDSYMLQRFTADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDA
HEDSFKSTDEAGQALLNTGHYASEEVKEK----------------------------LGI
LSEEKVSLLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA
LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAKDDVATRRDALLSRRNALHERAQF
RRAALEDSFHLQQFFRDSDELKSWINEKMKTATD-EAY-KDPSNLQGKVQKHQAFEAELS
ANQSRID-----ALQKSGQELVDGKHYASSEVSTRMDEVSSQWKKLLEATELKGIKLREA
NQQQQFNRNVEDIELWLYEVEGHLAS------------DDFGKDLTSVQNLQKK------
---------------HALLEAD-VAAHQDRIDGITIQARQFQ-----DAGHF---DADNI
RKKQEALVARYEALKEPMAARKQKLSDSLRLQQLFRDVEDEETWIREKEPIASSTNRGK-
--------------DLIGVQNLLKKHQALQAEISGHEPRIKAVTQKGEAMIDEG------
--HFAGEDVKAKLQELHNRWDGLKGKAAQRRQDLEDSLQAQQYFADANEAESWMREKEPI
VGSPDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALKEEAQACRQQVA-PTDDETGKEL
VLALYDYQEKSPREVTMKKGDILTLLNSTNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKKL--DPTQSSSRENLLDEQGSIGLRQDQ
IENQTAATKEVCSVS---------------------------------------------
----------------------------MRMKQVEELYGTLLELGEKRKDMLEKSCKKFM
LFREANELQQWINEKESALTNEE-VGSDLEQVEVLQKKFDDFQKDLKAN-ESRLRDIN--
------------------------------------KVASELESEGLMAEEAPVVQAQ--
--------------------------QVEVLGSAPGKDEADSKGASPWKSVRLAVQTTAN
FNTIKELNNRWRSLQQLAEDRSNMLGSAHEVQRFHRDADETKEWIEEKNQALNTDNY-GH
DLASVQALQRKHEGFERDLAALGDKVNSLGET--AERLIQSHP-EAVDDIQEKCTELNTA
WSSLVGRADQRKEKLGNSHDLQRFLSDFRDLMSWINGIRGLVSSDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAKDVTGAEALLERHQEHRTEIDARAGTFLAFEQFGQQLLAR
GHY-ASP--EIKQKLEALDRERADLEKAWVQRRMMLDQCLELQLFNRDCEQAENWMAARE
AFLAS--DDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQSFADQLISADHYAKPEIF
KRRSEVLDRWLRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTATDESYKDPT
NIQLS-------KLLSKHQKHQAFEAELHANADRIRGVIDTGNALIQRGACAGSEDAVKA
RLNALDEQWQFLVNK-SAEKSQKLKEANKQQNFNTGIKDFDFWLS---------------
----EVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNGQADSLMASNAFD
TSQVKDKRDAVNGRFGKIKSMAAGRRAKLNESHRLHQ-FFRDLDDEESWIKEKKLLVSSE
DYGRDLTGVQN-------------LRKKHKRLEAELGAHEPAIQSVLETGKKLS---DDN
TIGQEEIQQRLAQFVEHWRELKDLAAARGQRLEESLEYQQFVANVEEEEAWINEKLNLVG
SEDYGDTLAAVQGLLKKHEAFETDFTVHRDRVNDVCSNGDELVKKENHNVENIMAKMKAL
RGKVLELERAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL--KTDDYGRDLSSVQ
TLLTKQETFDAG--------------LQAFQQEGITNITALKDQLLAAKHVQSKAIEARH
ATLMKRWNQLLSNSAARKKKLLEAQDHFRKVEDLFLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSLEEIRALRDAHDAFRSSLSSAEADFSQLAELDRQIKSYNVVSNPYTWFT
MEA-LEETWSNLQKIIKERELEL----------------------------QKEQRRQEE
--------NDKLRQEFAQHANAFHQWLQETRTYLLDG---------------------SC
MVEESGTLESQLEATKRKHQEIRAM-----------------------------------
------------------------------------------RSQLKKIEDLGAAMEEAL
ILDNKYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNTTGVTEEALK------------------EFS
MMFKHFDKEKSGR---------------LNHQEFKSC-----------------------
-------LRSL---------------------GYDLPMV---------------------
EEGEPDPEFESILDIVDPN-----RDG----------NVSLQEYMA--------------
-FMISRET----------------------ENVKSSEEIESAFRALSAEN---KP-----
---------YVTKEELYQNLTKEQAD---YCIS-----HMKPYLDSK-GREIPSAFDFVE
FTRSLFVN---------------------------------------
>gi|115920116|ref|XP_785949.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------MTERGDIKVLE-----TAEDIQERRDQVLNRYETFK
ELAKERRQKLEEARQ--FQFFKRDADELET-----WILEK--------------------
---------LQTASDESYKDPVNLQAKLQKHQAFEAEVIAHSYVIEQLDDQGKVMIDAKH
FASDVIDARLIELHRLWELLLSKLREKGIKLLQAQKLVHYLREVEEVMYWIQDKEPFAAS
IETGVDLEHVEVLQKKFD--EFQKDLHAHEDRVAEVNSEANTLIEEGHPETDTIRNKQQD
LNDAWER-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKQLAIIRQEKLFGAMEIQRFNRDADETIGW-INEKDS
----ILSVDDYG------------------------------------------------
---------------------------------------------------RDLASVQAL
QRKHEGTERDLHALEDKVTALCQEADRLEQIH-TDHAPEIQSKKDEIANNWENLRSKADE
RKIRLVESANMHRFLADYRDTIAWTNDMKNIINADELAKDVPSAEALMERHQEHKGEIDA
HQDSFKQCAEEGQQLLDENHPQSDEVKEK----------------------------LVT
LADEKKALEELWEERRVTYEQCMDLQLFYRDTKQAQSWMTKQETFLVNEDLGDSIDEVEV
LIKKHDNFEKSLNAQEEKIKALDDFATKLIQSEHYASPDVDQCRKELLDRRGALINKADR
RRKLLEDSYRYQQFDQDADEVEAWIREKLKGTSD-ESY-KDPTNLQRKQLKHSVFESELQ
ANQQRIG-----KVRDEGNSMISEDHYNSPEIRERLENLNGLWMELLNTSEQKSQKLTQA
TEAAVVTRNIEEIATSLTDFDAILGS------------DDIGKDLVSVQKLRAK------
---------------LDMLESD-IGVKETAIQATRMQTTNMA-----MASHF---KADEI
SEKEKLVANKVEALRAPLQARKQKLEAAHRLHELLRDVDDEEAWIREKEPLASSTNRGR-
--------------DLIGVQNLIKKHQALNTEVAGHEPRITMVCKTGEQMLEEG------
--HFANDEIATKVKGLEEKWKNLKDKIAQRKDDLEDSLEAQQYFADANEAESWMQEKEPI
VASEDYGKDEDSAESQLKKHKTLMADLVAYRTTVEILKQQAEGCRQQDI-PISDDVSKEY
VVALYDYTEKSPREVSMKKGDVLVLLNSSNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKKM--DAAQSASQANLI-EDANIMRRQEN
IEQE--------------------------------------------------------
-------------------------------------YQSLLDKAGTRKEALEESVKRHS
LVREANDLIQWVNDKANVVESAE-VGDDLEQVEVYQKKFDDFQKDLKAN-ESRLLEIN--
------------------------------------MILETLDLEK--VPEADIVVQK--
------------------------------------------------------------
---VNDLNTEWQGLQKMTDERSASLGTAHEVQRFFRDADETKDWIDDKNKALNTENF-GH
DLHSVQALQRKHQGLERDLNALGKQVQTLDET--ADRLVQTHP-DQEEPIVAKRAEIDEA
WNTLQDRANARKDKLMDSYDLQRFLSDFRDLMSWTNGMKTLVASDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAKDVTGAEALLERHQELHTEMEAKAGTFQAFEAFGQELIKN
DHY-AAP--EVQEKLDILVKEREDLEVSWNDRRHKLDQCLELQLFLRDCEQAEAWMGARE
AFLAS--EGLTDSLDSVESLIKKHEDFDKALSIQEQKINAINSFAEQLVSNDHYDGPAIG
TKRDQVLERWHSLKDALIEKRSKLGESHTLQQFSRDADEVEAWISEKIQVATDESYLDPS
NIQ------------SKHQKHQAFEAEVAANAERIQAIMAVGQRLIDANQCGGTEDAVQA
RIVGIGDQWEYLVQR-SAEKSLKLKEANKQQTFHISVKDINFWLG---------------
----EMENALASEDVGRDLASVTNLIKKHQLLEDDIAAHEDRIQVLNKQADSFIEAGHFD
PENMRQTKENINQRYERIKDLTVDRRGKLNESHRVYQ-FFRDIDDEESWIKEKSLLTSSD
DYGRELTGVQN-------------LRKKHKRLETEIVSHEPAIQAVQDAGQSLM---QDV
ALNQEGVQQRLDQLASNWEELKQLANNRGSKLDESLTYQEFLAGIEEEEAWFNERMSLLC
SEDYGDTLAAVQGLLKKHKAFETDFTVHRDRVTDIKAQGETLIEAGNHNSEAISQRNESL
QRKLQELQEAAARRKANLDDNSAFLQFIWKADVVESWIGEKESFA--RSDDYGRDLSTVQ
TLLTKQETFDAG--------------LNAFEKEGIHAITTLKIKLVTANHAQTPAIQQRH
ANLIARWEKLLSDSNNRRQRLLRAQEQYREVEDLFLLFAKKASAFNSWFENA----EEDL
---TDPVRCNSVEEIQALKEAHEAFTASLSSAQNDLKQLAALDKQIKSYNVSSNPYTWFT
MEA-LEETWRNLQKIIKEREVEL----------------------------NREMERQEE
--------NDKLRKRFAQQANSFYQWITETRAAMVEE-----------------------
----SGNLETQLECLKAKINEVRAQ-----------------------------------
------------------------------------------KSTLKKIEDLGAKMEERL
ILDNRYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMTHNLE-----------
----------------------QQIQARNTTGVSEESLK------------------EFS
MMFKHFDKDKSGK---------------LDHTEFKSC-----------------------
-------LRSL---------------------GYDLPMV---------------------
EEGQDEPVFLSILDVVDPN-----RDG----------FVSLQEYMS--------------
-FMISRET----------------------ENVQSKDEIENAFRALSAEG---KP-----
---------YVTKQELYANLQTDLAE---YCIL-----RMEPYRDAK-GREVPHALDYGK
FTNNMFQN---------------------------------------
>gi|125976764|ref|XP_001352415.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MENFTPKEVKILE-----TVEDIQERREQVLSRYNEFK
IETRQKREKLEDSRR--FQYFKRDADELES-----WIHEK--------------------
---------LQAASEESYRDPTNLQAKIQKHQAFEAEVSAHSNAIVSLDNTGQEMINQQH
FASETIQRRLDELHQLWELLLSRLAEKGLKLQQALVLVQFLRQCEEVMFWIKDKETFVTA
DEFGQDLEHVEVLQRKFD--EFQKDMASQEYRVTEVNQLADKLIQDGHPERDTITKRKEE
LNEAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKQLAIVRQEKLFGAHEIQRFNRDADETVAW-IAEKDV
----VLSSDDYG------------------------------------------------
---------------------------------------------------RDLASVQAL
QRKHEGVERDLAALEDKVSTLGAEAQRLCSIH-ADHSDQIRDKQSEIANYWQSLTAKARE
RKQKLDESYYLHRFLADFRDLVSWINGMKAIISADELAKDVAGAEALLERHQEHKGEIDA
REDSFKLTTESGQKLLEREHYAAAEIQEK----------------------------LGA
LENDKSSLLSLWEDRRILYEQCMDLQLFYRDTEQADTWMAKQEAFLANEDLGDSLDSVEA
LIKKHEDFEKSLAAQEEKIKALDIFATKLIDGQHYAADDVAQRRQMLLARRAALQEKSAK
RRQLLEDSNRYQQFERDCDETKGWISEKLKFATD-DSY-LDPTNLNGKMQKHQNFEHELN
ANKSRIE-----DITNVGTELIEKQHYAADQINTRMQEIVVLWETLVQASDKKGCKLNEA
CQQQQFNRTIEDIELWLSEIEGQLLS------------EDHGKDLTSVQNLQKK------
---------------HALLEAD-VMAHQDRIESIKVAANKFI-----ESGHF---DADNI
RNKEGNLSARYAALAAPMSERKQHLSDSLHVQQLFRDLEDEAAWIREKEPIAASTNRGR-
--------------DLIGVQNLIKKHQAVLAEINNHEARLLNVISSGDNMLKDQ------
--PFASDDIRQRLEALQEQWNNLKERSNQRKQDLDDSLQAHQYFADANEAESWMREKEPI
ATGSDYGKDEDSSEALLKKHEALVSDLEAFGNTIQALQEQAKNCRQQET-PVVDITGKEC
VVALYDYTEKSPREVSMKKGDVLTLLNSNNK-----------------------------
------------DWWKVEVNDRQGFVPAAYIKKI--EAGLSASQQNLV-DNHSIAKRQNQ
INSQ--------------------------------------------------------
-------------------------------------YDNLLALARERQNKLNETVKAYV
LVREAADLAQWIRDKENHAQIADVVGEDLEEVEVLQKKFDDFNDDLKAN-EVRLANMN--
------------------------------------EIAVQLTSLG-QTEAALKIQTQ--
------------------------------------------------------------
---MQDLNEKWNNLQTLTTEKASQLGSAHEVQRFHRDIDETKDWIAEKANALNNDDL-GK
DLRSVQTLQRKHEGVERDLAALRDKIRQLDET--ANRLMQSHP-DTAEQTYAKQKEINEM
WDQIITKSTARKEKLLDSYDLQRFLSDYRDLLAWINSMMSLVTSDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LANDVTGAEALIERHQEHRTEIDARAGTFGAFEQFGNELLQA
NHY-ASP--EIKEQIEDLAKAREDLEKAWTERRLQLEQNLDLQLYMRDCELAESWMSARE
AFLNA--DDDANAGGNVEALIKKHEDFDKAINGHEQKIAALQTVADQLIAQNHYASTAVD
EKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQLATEESYKDPA
NIQ------------SKHQKHQAFEAELAANADRIQSVLAMGGNLIDKKQCSGSEDAVQK
RLTQIADQWEYLTHK-TTEKSLKLKEANKQRTYIAAVKDLDFWLG---------------
----EVESLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFD
TAGIQEKRQSINERYERICNLAAHRQARLNEALTLHQ-FFRDIADEESWIKEKKLLVGSD
DYGRDLTGVQN-------------LKKKHKRLEAELASHEPAIQAVQEAGEKLM---DVS
NLGVPEIEQRLKALNQAWAELKNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLS
VEDYGDSMAAVQGLLKKHDAFETDFTAHKDRCSLICDQGSELVEAKNHHGDSIAQRCQQL
RNKLENLNALAARRKGALLDNSAYLQFMWKADVVESWIDDKENYV--RSDEFGRDLSTVQ
TLLTKQETFDAG--------------LNAFEQEGIHNITALKDQLINASHAQSPAILKRH
GDVIARWQSLRDASDTRKQRLLAMQEQFRQIEELYLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSIEEIRALRDAHAQFQASLSSAEADFKALAALDQKIKSFNVGPNPYTWFT
MEA-LEETWRNLQKIIEERDGEL----------------------------AKEAKRQEE
--------NDKLRKEFAKHANLFHQWLTETRTSMMEG-----------------------
----SGSLEQQLDALRVKATEVRAR-----------------------------------
------------------------------------------RVDLKKIEELGALLEEHL
ILDNRYT--EHSTVGLAQQWDQLDQLSM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNHSGVSEDSLK------------------EFS
MMFKHFDKDKSGK---------------LNHQEFKSC-----------------------
-------LRAL---------------------GYDLPMV---------------------
EEGQPDPEFEAILDVVDPN-----RDG----------YVSLQEYIA--------------
-FMISKET----------------------ENVQSYEEIENAFRAITAAD---RP-----
---------YVTKEELYCNLTKDMAD---YCVQ-----RMKPFSEPRSGQPIKDALDYID
FTRTLFQN---------------------------------------
>gi|115430237|ref|NP_066022.2|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MAQVPGEVDNMEGLPA-PNNNPAARWESPDRGWEREQ
PAASTAAASLFECSR--IKALADEREAVQKKTFTKWVNSH--------------------
---------LARVGCHIG----DLYVDLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHS--
------------------------------LENVDKALQFLKEQRVHLENVGSHDIVDGN
HRLTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNI-----QN
FTTSWRD-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------GLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHL
GLARLLDPEDVN------------------------------------------------
---------------------------------------------------MEAPDEKSI
ITYVVSFYHYFS----KMKALAVEGKRIGKV--LDQVLEV----GKIIERYEELAA----
-------------------ELLAWIHRTVGLISNQKFANSLSGVQQQLQAFTAY------
------CTLEKPVKFQEKGN-------------------------------------LEV
LLFSIQSKLRACNRR------------LFVPREGCGIW-----------DIDKAWGELE-
----KAEHEREAALRAELIR---------------------QEKLELLAQR---------
-------------FDHKVAMRESWLNENQRLVSQ-DNFGYELPAVEAAMKKHEAIEADIA
AYEERVQ-----GVAELAQALAAEGYYDIRRVAAQRDSVLRQWALLTGLVGARRTRLEQN
LALQKVFQEMVYMVDWMEEMQAQLLS------------RECGQHLVEADDLLQK------
---------------HGLLEGD-IAAQSERVEALNAAALRFS-----QLQGYQPCDPQVI
CNRVNHVHGCLAELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGA
AGAAGAAGTAGGAHDLSSTARLLAQHKILQGELGGRRALLQQALRCGEELVAAGGAVGPG
ADTVHLVGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRL
AAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVSGLRRQLA--------TLGGASGAGP
LVV---------------------------------------------------------
----------------------------------------------------ALQVRVVE
AEQL--------------------------------------------------------
-------------------------------------FAEVTEVAALRRQWLRDALAVYR
MFGEVHACELWIGEKEQWLLSMR-VPDSLDDVEVVQHRFESLDQEMNSL-MGRVLDVN--
------------------------------------HTVQELVEGG--HPSSDEVRSC--
------------------------------------------------------------
---QDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAPRAGG
------ALQWRLSGLEAALQALEPRQAALLEE--AALLAERFP-AQAARLHQGAEELGAE
WGALASAAQACGEAVAAAGRLQRFLHDLDAFLDWLVRAQEAAGGSEG-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------PLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAA
DGAELGPGLALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQALVVLRNQE
MALSG--AELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQ
EAVTRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTREDNH
KLH------------KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAA--SVRK
KLGEIRQCWAELEST-TQAKARQLFEASKADQLVQSFAELDKKLL---------------
----HMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWYREVGELQAQTAAL-PLEPAS
KELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQ-VAHDLDDELAWVQERLPLAMQT
ERGNGLQAVQQ-------------HIKKNQGLRREIQAHGPRLEEVLERAGALA---SLR
SPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGEQELLMM
SEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQV
DRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVA--GSPELGQDFEHVS
VLQEKFSEFASE--------------TGMAGRERLAAVNQMVDELIECGHTAAATMAEWK
DGLNEAWAELLELMGTRAQLLAASRELHK--------FFSDARELQGQIEEK----RRRL
PRLTTPPEPRP--SASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIAS
REQEVLQGWKELLSACEDARLHVSSTADALRFHSQVRDLLSWMDGIASQIGAADKPRDVS
SVEVLMNYHQGLKTELEARVPELTTCQELGRSLLLNK-----------------------
-SAMADEIQAQLDKLGTRKEEVSEKWDRHWEWL---------------------------
--------------------QQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVE
QLIRRHEAFRKAAAAWEERFSSLRRLTTIEKIKAEQSKQPPTPLLGRKFFGDPTELAAKA
APLLRPGGYERGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPEIPGRVEP
AALPAAPEDAAETPATPA--AAEQVRPRPERQESADRAE------------------ELP
RRRRPERQESVDQSEEAARRRRPERQESAEHEAAHSLTLGRYEQMERRRERRERRLERQE
SSEQEMPIRGDLVKGKATLADIVEQLQEKEA-GPGLPAG-PSLPQPRELPPGRLPNGLEL
PERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHE
GFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGFYKDSKGPASGSTHGG---EPLLSLH
KATSEVASDYKKKKHVFKLQTQDGSE---FLLQAKDEEEMNGWLEAV-ASSVAEHAEIAR
WGQTLPTTSSTDEGNPKREGGDRRASGRRK-----------------
>gi|149738008|ref|XP_001500685.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPSGVKVLE-----TAEDIQERRQQVLDRYHRFK
ELSTLRRQKLEDSYR--FQFFQRDAEELEK-----WIQEK--------------------
---------LQIASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGH
FASETIRTRLMELHRQWELLLEKMREKGVKLLQAQKLVQYLRECEDVMDWINDKEAIVTS
EELGQDLEHVEVLQKKFE--EFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDE
VNAAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKGLALQRQGKLFGAAEVQRFNRDVDETISW-IKEKEQ
----LMASDDFG------------------------------------------------
---------------------------------------------------RDLASVQAL
LRKHEGLERDLAALEDKVKALCAEADRLQQSH-PLSATQIQVKREELITNWEQIRTLAAE
RHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDA
HEDSFKSADESGQALLAAGHYASDEVKEK----------------------------LTI
LSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA
LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMY
RRAQLADSFHLQQFFRDSDELKSWVNEKMKTATD-EAY-KDPSNLQGKVQKHQAFEAELS
ANQSRID-----ALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKLREA
NQQQQFNRNVEDIELWLYEVEGHLAS------------DDYGKDLTNVQNLQKK------
---------------HALLEAD-VAAHQDRIDGITIQARQFQ-----DAGHF---DAENI
KKKQEALVARYEALKEPMIARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGK-
--------------DLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGHAMVEEG------
--HFAAEDVKAKLNELNQKWESLKSKASQRRQDLEDSLQAQQYFADANEAESWMREKEPI
VGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVA-PMDDETGKEL
VLALYDYQEKSPREVTMKKGDILTLLNSTNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKKL--DPAQSASRENLLEEQGSIALRQEQ
IDNQ--------------------------------------------------------
-------------------------------------YRSLLELGEKRKGMLEKSCKKFM
LFREANELQQWINEKEAALTSEE-VGADLEQVEVLQKKFDDFQKDLKAN-ESRLKDIN--
------------------------------------KVAEALESEGLMAEEVQAVQQQ--
----------------------------EVYGAMP-RDEGDSKTASPWKSARLMVHTVAT
FNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNY-GH
DLASVQALQRKHEGFERDLAALGDKVNSLGET--AERLIQSHP-ESAEDLQEKCTELNQA
WSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAH
RHY-ASP--EIKEKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAARE
AFLNT--EDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQSFADQLIAAGHYAKGDIS
SRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPT
NIQLS-------KLLSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKA
RLAALADQWQFLVQK-SAEKSQKLKEANKQQNFNTGIKDFDFWLS---------------
----EVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFD
TSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQ-FFRDMDDEESWIKEKKLLVSSE
DYGRDLTGVQN-------------LRKKHKRLEAELAAHEPAIQGVLDTGKKLS---DDN
TIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVA
SEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLVKKNNHHEENISSKMKCL
NGKVSDLEKAASQRKAKLDENSAFLQFNWKADVVESWIGEKENSL--KTDDYGRDLSSVQ
TLLTKQETFDAG--------------LQAFQQEGIANITALKDQLLAAKHIQSKAIEARH
ASLMKRWSQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFT
MEA-LEETWRNLQKIIKERELEL----------------------------QKEQRRQEE
--------NDKLRQEFAQHANAFHQWIQETRTYLLDGIAYRRVIRVCQYEVGDDLSGRSC
MVEESGTLESQLEATKRKHQEIRAM-----------------------------------
------------------------------------------RSQLKKIEDLGAAMEEAL
ILDNKYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNTTGVTEEALK------------------EFS
MMFKHFDKDKSGR---------------LNHQEFKSC-----------------------
-------LRSL---------------------GYDLPMV---------------------
EEGEPDPEFEAILDTVDPN-----RDG----------HVSLQEYMA--------------
-FMISRET----------------------ENVKSSEEIESAFRALSSEG---KP-----
---------YVTKEELYQNLTREQAD---YCVS-----HMKPYVDSK-GRELPTAFDYVE
FTRSLFVN---------------------------------------
>gi|109017475|ref|XP_001117106.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MEQFPKETVVESSGPKVLE-----TAEEIQERRQEVLTRYQRFK
ERVAERGQKLEDSYH--LQVFKRDADDLGK-----WIMEK--------------------
---------VNILNDESYGDPTNIQGKYQKHQSFEAEVQTKSRVMSELEKTREERFTMGH
SAHEETKAHIEELRRLWDLLLELTLEKGALLLRALKFQQYVQECADILEWIGDKEAIATS
VELGEDWERTEVLQKKFE--DFQVDLVAKEGRVDDVNQYANECAEEKHPELPLIQSKQEE
VNAAWER-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LRGLALQRQKALSSAADLQRFKRDMTDAIQW-IKEKEP
----VLTSEDYG------------------------------------------------
---------------------------------------------------KDLVASEGL
FHSHKGLERNLAVMSDKVKELCAKAEKLTLSH-PSDAPQIQEMKEDLVSNWEHIRALATS
RYEKLQATYWYHRFSSDFDELSGWMKEKTAAINADELPTDVAGGEVLLDRHQQHKHEIDS
YDDRFQSAKETGEDLLDANHEASDEVREK----------------------------MEI
LASNWDALLELWDQRHRQYEQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSLGSAEA
LLQKHDDFEEAFTAQEEKITTVDKTATKLIGDNHYDSENIAAIRDGLLARRDALRGRATT
RRRLLEDSLLLQQLYQDSDDLKNWINKKKKLADD-EDY-KDTQNLKSRVQKQQVFEKELA
DNEIVLE-----NIQKTGQEMIDSGHYASDNVTTRLSEVASLWKELLEATKQKGTQLDEA
NQRLQFENNAEDLQRWLEEVEWQVAS------------EDYGKGLADVQNRLRK------
---------------HGLLESA-VAARQDQVNILTELAAYFE-----KIGHP---DSKDI
QARQESLVCRFEALKEPLATRKKKLLDLLHLQLICRDTEDEEAWIQETEPSATSTYLGK-
--------------DLIASKKLLNRHKVILENIASHEPRIQVITERGNKMVEEG------
--HFAAEDVASRVKSLNQNMESLRARAARRQNDLEANVQFQQYLADLHEAETWIREKEPI
VDNTNYGADEEAAGALLKKHEAFLLDLNSFGDSMKALQNQAEACQQQQAAPVEGAAGEQR
VMALYDFQARSPREVTMKKGDVLTLLSSINK-----------------------------
------------DWWKVEADDHQGFVPAVYVKRLAHDEFPMLPQRRRE-EPGNIAQRQEQ
IENQ--SDTSQSSSD---------------------------------------------
----------------------------SLSHIVSRLYRSLLDRAEERRRHLLQRYNEFL
LAYEAGDMLEWIQEKKAEN-----TGVELDDVWELQKKFDEFQKDLKTN-EPRLRDIN--
------------------------------------KVADDLLFEGLLTPEGAQIR----
------------------------------------------------------------
----QELNARWGSLQRLADEQRQLLGSAHAVEVFHREADDTKEQIEKKCQALSAADP-GS
DLFSVQALQRQHEGFERDLVPLGDKVTILGET--AERLSESHP-DATEDLQRQKMELNEA
WEDLQGRTKDRKESLNEAQKFYLFLSKARDLQNWISSIGGMVSSQE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAEDLTGIEILLERHQEHRADMEAEAPTFQALEDFGAELIDS
EHR-ASP--EIEKKLQAVRLERDDLEKAWEQRKKILDQCLELQMFQGNCDQAENWMVARE
NALRS--DDKD-SLNSLEALKKKQDDLHKAITAQEGKITDLQHFAERLIADEHYAKEEIA
TRLQRVLDRWKALKAQLIAEQTKLGDQADLKQFYRDLEELEEWISEMLPTACDESYKDPT
NIQAS-------SIQRKYLKHQAFANEVYGRADQVDATIDLGRSLIERSTCDCDEEAMKE
QLEQLKEHWDYLLEK-TTDKGQKLNEASRQQRFNTSIQDFEFWLS---------------
----EAETLLAMKDQARDLASAGNLLKKHQLLETEMLAREDALKDLNTLAEDLLSSGTFN
VDQITEKKDSVNKRFLNVQDLAAAHHEKLKEAYALFQ-FFQDLDDEESWIEEKLLRVSSQ
DYGRDLQGVQN-------------LLKKHRRLEGELVAHEPAIQNVLDMAEKLK---DKA
AVGEEEIQLRLAQFVEHWEKLKELAKARGLQLEESLEYLQFMQNAEEEEAWINEKNAMAV
RGDSGDTLAATQSLLMKHEALENDFAVHETRVQNVCAQGEDILNKVSYQNKEISSKIEAL
NEKTPSLAKAIAAWKLQLKDDYDFQEFNWKADVVEAWIADKETSL--KTNGNGADLGDFL
TLLANQDTLDAS--------------LQSFQQERLPEITDLKDQLIAAQHSQSKAIEERY
AALLKRWEQLLEASAVHRQKLLEKQLPLQKAEDLFMEFAHKASAFNNWCEKA----EENL
---SEPVHCVSLNEIRQLQKDHEDFLASLAGAQGDFKCLLELDQQIKALGVPSSPYTWLT
VEV-LERTWKHLSDIIEEREQEL----------------------------QKEEARQVK
--------NFEMCQEFEQNASAFLQWILETRAYFLDG----------------------S
LLKETGTLESQLEANKRKQKEIQAM-----------------------------------
------------------------------------------KRQLTKIEDLGDNMEDAL
ILDIKY-----STIGLAQQWDQLYQLGL--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQAKDTIGVSEETLK------------------EFS
TIYKHFDENLTGH---------------LTHKEFLSC-----------------------
-------LRGL---------------------NYYLPMV---------------------
EEDEHEPEFKKFLDAVDPG-----RKG----------YISLEDYTA--------------
-FLIHKES----------------------ENIKSSNEIENAFQA-LAEG---KS-----
---------YITKEDMKQALTPEQVS---FCAT-----HMQQYMDPQ-GRSHLSGYDYAG
FTNSYFGNS--------------------------------------
>gi|17136504|ref|NP_476739.1|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MENFTPKEVKILE-----TVEDIQERREQVLSRYNDFK
IETRQKREKLEDSRR--FQYFKRDADELES-----WIHEK--------------------
---------LQAASEESYRDPTNLQAKIQKHQAFEAEVSAHSNAIVSLDNTGQEMINQQH
FASESIQVRLDELHKLWELLLSRLAEKGLKLQQALVLVQFLRQCEEVMFWIKDKETFVTA
DEFGQDLEHVEVLQRKFD--EFQKDMASQEYRVTEVNQLADKLVQDGHPERDTITKRKEE
LNEAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKQLAIVRQEKLFGAHEIQRFNRDADETVAW-IAEKDV
----VLSSDDYG------------------------------------------------
---------------------------------------------------RDLASVQAL
QRKHEGVERDLAALEDKVSTLGAEAQRLCSIH-ADHSDQIRDKQAEIANYWQSLTTKARE
RKQKLDESYYLHRFLADFRDLVSWINGMKAIISADELAKDVAGAEALLERHQEHKGEIDA
REDSFKLTTESGQKLLEREHYAAAEIQEK----------------------------LAA
LENDKSSLLSLWEDRRILYEQCMDLQLFYRDTEQADTWMAKQEAFLANEDLGDSLDSVEA
LIKKHEDFEKSLAAQEEKIKALDIFATKLIDGQHYAADDVAQRRQMLLARRAALQEKSSK
RRQLLEDSNRYQQFERDCDETKGWISEKLKFATD-DSY-LDPTNLNGKMQKHQNFEHELN
ANKSRIE-----DITNVGTELIEKQHYAADQINTRMQEIVVLWETLVQASDKKGTKLNEA
CQQQQFNRTIEDIELWLSEIEGQLLS------------EDHGKDLTSVQNLQKK------
---------------HALLEAD-VMAHQDRIESIKVAANKFI-----ESGHF---DADNI
RNKEGNLSARYAALAAPMGERKQHLLDSLQVQQLFRDLEDEAAWIREKEPIAASTNRGR-
--------------DLIGVQNLIKKHQAVLAEINNHEARLLNVISSGENMLKDQ------
--PFASDDIRQRLEALQEQWNTLKEKSSQRKQDLDDSLQAHQYFADANEAESWMREKEPI
ATGSDYGKDEDSSEALLKKHEALVSDLEAFGNTIQALQEQAKNCRQQET-PVVDITGKEC
VVALYDYTEKSPREVSMKKGDVLTLLNSNNK-----------------------------
------------DWWKVEVNDRQGFVPAAYIKKI--DAGLSASQQNLV-DNHSIAKRQNQ
INSQ--------------------------------------------------------
-------------------------------------YDNLLALARERQNKLNETVKAYV
LVREAADLAQWIRDKENHAQIADVVGEDLEEVEVLQKKFDDFNDDLKAN-EVRLANMN--
------------------------------------EIAVQLTSLG-QTEAALKIQTQ--
------------------------------------------------------------
---MQDLNEKWNNLQTLTAEKASQLGSAHEVQRFHRDIDETKDWIAEKANALNNDDL-GK
DLRSVQTLQRKHEGVERDLAALRDKIRQLDET--ANRLMQSHP-DTAEQTYAKQKEINEM
WDQIITKSTARKEKLLDSYDLQRFLSDYRDLLAWINSMMSLVTSDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LANDVTGAEALIERHQEHRTEIDARAGTFGAFEQFGNELLQA
NHY-ASP--EIKEKIEDLAKAREDLEKAWTERRLQLEQNLDLQLYMRDCELAESWMSARE
AFLNA--DDDANAGGNVEALIKKHEDFDKAINGHEQKIAALQTVADQLIAQNHYASNLVD
EKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQLATEESYKDPA
NIQ------------SKHQKHQAFEAELAANADRIQSVLAMGGNLIDKKQCSGSEDAVQK
RLTQIADQWEYLTHK-TTEKSLKLKEANKQRTYIAAVKDLDFWLG---------------
----EVESLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFD
TAGIQEKRQSINERYERICNLAAHRQARLNEALTLHQ-FFRDIADEESWIKEKKLLVGSD
DYGRDLTGVQN-------------LKKKHKRLEAELGSHEPAIQAVQEAGEKLM---DVS
NLGVPEIEQRLKALNQAWAELKNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLS
VEDYGDSMAAVQGLLKKHDAFETDFTAHKDRCSLICDQGSELVEAKNHHGESIAQRCQQL
RLKLDNLSALAARRKGALLDNSAYLQFMWKADVVESWIDDKENYV--RSDEFGRDLSTVQ
TLLTKQETFDAG--------------LNAFEQEGIHNITALKDQLINASHAQSPAILKRH
GDVIARWQKLRDASNTRKDRLLAMQEQFRQIEELYLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSIEEIRALRDAHAQFQASLSSAEADFKALAALDQKIKSFNVGPNPYTWFT
MEA-LEETWRNLQKIIEERDGEL----------------------------AKEAKRQEE
--------NDKLRKEFAKHANLFHQWLTETRTSMMEG-----------------------
----SGSLEQQLEALRVKATEVRAR-----------------------------------
------------------------------------------RVDLKKIEELGALLEEHL
ILDNRYT--EHSTVGLAQQWDQLDQLSM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNHSGVSEDSLK------------------EFS
MMFKHFDKDKSGK---------------LNHQEFKSC-----------------------
-------LRAL---------------------GYDLPMV---------------------
EEGQPDPEFEAILDVVDPN-----RDG----------YVSLQEYIA--------------
-FMISKET----------------------ENVQSYEEIENAFRAITAAD---RP-----
---------YVTKEELYCNLTKDMAD---YCVQ-----RMKPFSEPRSGQPIKDALDYID
FTRTLFQN---------------------------------------
>gi|126297657|ref|XP_001363278.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPSGVKVLE-----TAEDIQERRQQVLDRYHRFK
ELSTLRRQKLEDSYR--FQFFQRDAEELEK-----WIQEK--------------------
---------LQIASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGH
FASETIRARLMELHRQWELLLEKMREKGVKLLQAQKLVQYLRECEDVMDWITDKEAIVTS
EELGQDLEHVEVLQKKFE--EFQTDMAAHEERVNEVNQFAAKLIQEQHPEEDLIKTKQDE
VNAAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKGLALQRQGKLFGAAEVQRFNRDVDETISW-IKEKEQ
----LMASDDFG------------------------------------------------
---------------------------------------------------RDLASVQAL
LRKHEGLERDLAALEDKVKALCAEADRLQQSH-PMSATQIQVKREELITNWEQIRTLAAE
RHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDA
HEDSFKSADESGQALLAAGHYASDEVREK----------------------------LAI
LSDERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA
LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMY
RRAQLADSFHLQQFFRDSDELKSWVNEKMKTATD-EAY-KDPSNLQGKVQKHQAFEAELS
ANQSRID-----ALEKAGQKLIDVNHYAKDEVATRMNEVISLWKKLLEATELKGIKLREA
NQQQQFNRNVEDIELWLYEVEGHLAS------------DDYGKDLTNVQNLQKK------
---------------HALLEAD-VAAHQDRIDGITIQARQFQ-----DAGHF---DADNI
KKKQEALVARYEALKDPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGK-
--------------DLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEG------
--HFAAEDVKAKLNELNQKWESLKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPI
VGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVA-PTDDETGKEL
VLALYDYQEKSPREVTMKKGDILTLLNSTNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKKL--DPAQSASRENLLEEQGSIALRQEQ
IDNQ--------------------------------------------------------
-------------------------------------YHSLLELGEKRKGMLEKSCKKFM
LFREANELQQWINEKEATLTNEE-VGTDLEQVEVLQKKFDDFQKDLKAN-ESRLKDIN--
------------------------------------KVAEDLESEGLMAEEVQAVQQQ--
----------------------------EVYGMMP-RDDTDSKTASPWKSARLMVHTVAT
FNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNY-GH
DLASVQALQRKHEGFERDLAALGDKVNSLGET--AERLIQSHP-ESAEDLQEKCTELNQA
WNSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAR
GHY-ASP--EIKEKLDILDQERADLEKAWIQRRMMLDQCLELQLFHRDCEQAENWMAARE
AFLNT--EDRGDSLDSVEALIKKHEDFDKAINVQEEKIAALQSFADQLISADHYAKGDIS
NRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPT
NIQLS-------KLLSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKA
RLAALADQWQFLVQK-SAEKSQKLKEANKQQNFNTGIKDFDFWLS---------------
----EVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNGQADSLMTSSAFD
TSQVKEKRDTINSRFQRIKGMAAARRAKLNESHRLHQ-FFRDMDDEESWIKEKKLLVSSE
DYGRDLTGVQN-------------LRKKHKRLEAELAAHEPAIQAVLDTGKKLS---DDN
TIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVA
SEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISAKMKGL
NGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL--KTDDYGRDLSSVQ
TLLTKQETFDAG--------------LQAFQQEGIANITALKDQLLAAKHVQSKAIEARH
ASLMKRWNQLLANSATRKKKLLEAQEHFRKVEDLFLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFT
MEA-LEETWRNLQKIIKERELEL----------------------------QKEQRRQEE
--------NDKLRQEFAQHANAFHQWIQETRTYLLDGIAYRRVIRVYQYEVGDDLSGRSC
MVEESGTLESQLEATKRKHQEIRAM-----------------------------------
------------------------------------------RSQLKKIEDLGAAMEEAL
ILDNKYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNTTGVTEEALK------------------EFS
MMFKHFDKDKSGR---------------LNHQEFKSC-----------------------
-------LRSL---------------------GYDLPMV---------------------
EEGEPDPEFEAILDTVDPN-----RDG----------HVSLQEYMA--------------
-FMISRET----------------------ENVKSSEEIESAFRALSSEG---KP-----
---------YVTKEELYQNLTREQAD---YCIS-----HMKPYVDGK-GRELPSAFDYVE
FTRSLFVN---------------------------------------
>gi|109458421|ref|XP_218364.4|	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------MRIWPSGGPAGPNRA---GPGPATNARR
EGGAARRASGTASAAGAQALPSPMAQVPGEVDNMEGPAASNNNNPAARWESPDRGWDREP
PAAANAAASLFECSR--IKALADEREAVQKKTFTKWVNSH--------------------
---------LARVGCHIG----DLYADLRDGFVLTRLLEVLSGEQLPRPTRGRMRIHS--
------------------------------LENVDKALQFLKEQRVHLENVGSHDIVDGN
HRLTLGLVWTIILRFQIQVIKIETEXXXETRSXKDVLLFWATQQIPGEPELQRKTQSQK-
----FKQT----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------NNEQ-TGSFFNYTVHKYMPDLVDLSKLTKSNANYNLQRAFRTAEQHL
GLARLLDPEDVN------------------------------------------------
---------------------------------------------------MEAPDEKSI
ITYVVSFYHYFS----KMKALAVEGKRIGKV--LDQVLEV----DKIIERYEELAA----
-------------------ELLAWIHRTVDLISNQKFANSLSGVQQQLQAFTAY------
------CTLEKPVKFQEKGN-------------------------------------LEV
LLFSIQSKLRAHNRR------------LFVPREGCGIW-----------DIDKAWGELE-
----KAEHEREAALRAELIR---------------------QEKLELLAQR---------
-------------FDHKVAMRESWLNENQRLVSQ-DNFGYELPAVEAAMKKHEAIEADIA
AYEERVQ-----GVAELAQALAAEGYYDARRVAAQRDSVLRQWALLTGLVGARRTRLEQN
LALQKVFQEMVYMVDWMEEMQTQLLS------------RECGQHLVEADDLLQK------
---------------HGLLEGD-IAAQSERVEALNAAALRFS-----QLQGYQPCDPQVI
CNRVNHVHGCLSELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEATSGSG-
-GAAGTAG---GAHDLSSTARLLAQHKILQGELGGRRALLQQALRRGEELAAAGGSVGPG
AEPLHLAGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRL
AAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVGGLRRQLA--------TLGGASGAGP
LVV---------------------------------------------------------
----------------------------------------------------ALQVRVVE
AEQL--------------------------------------------------------
-------------------------------------FAEVTEVAALRRQWLRDALAVYR
MFGEVHACELWIGEKEQWLLAMR-VPDSLDDVEVVQHRFESLDQEMNSL-MGRVLDVN--
------------------------------------QTVQELVEGG--HPSSDEVRSC--
------------------------------------------------------------
---QDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAPRAGG
------ALQWRLSGLEAALQALEPRQAALLEE--AALLAERFP-AQATRLHQGAEELGAE
WGALAGAAQACGEAVAAAGRLQRFLRDLDTFLDWLVRAQEAAGAVEG-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------PLPRSLEEADGLLARHAALKEEVDQREEDYARIVAASEALLAS
DGAELGPGLALDEWLPHLEVGWHKLLGLWEERREALVQAHVYQLFLRDLCQALAVLRNQE
VALSG--AELPCTVESVEEAMKRHRDFLTTMELNQQKMQVAVQAAEGLLRQGNAYGEQAQ
EAVARLLEKSQENQLRAQQWMQKLLDQLVLQHFLRDCHELDGWIHEKMLMARDGTREDSH
KLH------------KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAA--SVRK
KLGEIRQCWAELEST-TQAKARQLFEASKADQLVQSFAELDKRLL---------------
----HMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQTAAL-PLEQAS
KELVGERQSAVGERLVRLLEPLQERRRLLLASKELHQ-VAHDLDDELAWVQERLPLAMLT
ERGTGLQAVQQ-------------HIKKNQGLRREIQAHGPRLEEVLERAGVLA---SLR
SPEAEAVRRGQEQLQSAWTGLREATERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMM
SEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQV
DRLYVALKELGEERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVA--GSPELGQDFEHVS
VLQEKFSEFASE--------------TGTAGRERLAAVNQMVDELIECGHTAAATMAEWK
DGLNEAWAELLELMGTRAQLLAASRELHK--------FFSDARELQGQIEEK----RRRL
PRLTAPPEPRP--SASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIAS
REQEVLQGWKELLAACEDARLHVSSTADALRFHSQARDLLSWMDGIAGQIGAADKPRDVS
SVEVLMNYHQGLKTELEARVPELTACQELGRSLLLNK-----------------------
-SAMADEIQAQLDKLGSRKEEVSEKWDRHWEWL---------------------------
--------------------QQMLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVE
QLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRKFFGDPTELAAKA
APLLRPGGYDRGLEPLARRASDTLSAEVRTRVGYVRQELKPERLQPRIDRLPETSGKVEP
AAPTAAALDTTDTPGTPA--VTEQVRPRPERQELADRAE------------------ELP
RRRRSERQESTDQPEEAARRRRPERQESADHEGPHSLTLGRYEQMERRRERRERRIERQE
SSEQETPTRGELVKGKATLADIVEQLQEKEA-GPGLPAAVPSLPQPRELPPGRLPNGLEP
PERTPRPDRPRARDRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPPPTHTVQHE
GFLLRKRELDA-NRKSSNRSWVNLYCVLSKGELGFYKDSKGPASGGTHGG---EPLLSLH
KATSEVASDYKKKKHVFKLQTQDGSE---FLLQAKDEEEMNGWLEAV-ANSVAEHAEIAR
WGQTLPTTSSTDEGNPKREGGERRASGRRK-----------------
>gi|114560504|ref|XP_001169857.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MEQFPKETVVESSGPKVLE-----TAEEIQERRQEVLTRYQSFK
ERVAERGQKLEDSYH--LQVFKRDADDLGK-----WIMEK--------------------
---------VNILTDKSYEDPTNIQGKYQKHQSLEAEVQTKSRLMSELEKTREERFTMGH
SAHEETKAHIEELRRLWDLLLELTLEKGALLLRALKFQQYVQECADILEWIGDKEAIATS
VELGEDWERTEVLHKKFE--DFQVELVAKEGRVVEVNQYANECAEENHPDLPLIQSKQNE
VNAAWER-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LRGLALQRQKALSNAADLQRFKRDVTEAIQW-IKEKEP
----VLTSEDYG------------------------------------------------
---------------------------------------------------KDLVASEGL
FHSHKGLERNLAVMSDKVKELCAKAEKLTLSH-PSDAPQIQEMKEDLVANWEHIRALATS
RYEKLQATYWYHRFSSDFDELSGWMNEKTAAINADELPTDVAGGEVLLDRHQQHKHEIDS
YNDRFESARETGQDLLNANHEASDEVREK----------------------------MEI
LTKNWAALLELWNKRHHQYEQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSLGSAEA
LLQKHEDFEEAFTAQEEKITTVDKTATKLIGDNHYDSDNIEAIRDGLLARRDALREKAAT
RHRLLKESLLLQKLYEDSDDLKNWINKKKKLADD-EDY-KDIQNLKSRVQKQQVFEKELE
VNKTLLE-----NIQKTGQEMIEGGHYASDNVTTRLSEVVSLWKELMEATEQKGTQLHEA
NQQLQFENNAEDLQHWLEDVEWQVTS------------EDYGKGLADVQNRLRK------
---------------HGLLESA-VAARQDQVDTLTDLAAYFE-----EIGHP---DSKDI
RARQESLVCRFEALKEPLATRKKNLLDRLHLQLICRDTEDEEAWIQETEPSATSTYLGK-
--------------DLIASKKLLNRHRVILENIASHEPRIQEITERGNKMVEEG------
--HFAAEDVASRVKSLNQNMESLCARAARRQNNLEANVQFQQYLADLHEAETWIREKEPI
VDNTNYGADEEAAGALLKKHEAFLLDLNSFGDSMKALRNQANACQQQQAAPVEGAAGEQR
VMALYDFQARSPREVTMKKGDVLTLLSSINK-----------------------------
------------DWWKVEAADHQGIVPAVYVRRLAHDEFPMLPQRRRE-EPGNITQRQEQ
IENQ--------------------------------------------------------
-------------------------------------YRSLLDRAEERRRRLLQRYNEFL
LAYEAGDMLEWIQEKKAEN-----TGVELDDVWELQKKFDEFQKDLNTN-EPRLRDIN--
------------------------------------KVADDLLFEGLLTPEGAQIR----
------------------------------------------------------------
----QELNARWGSLQRLADEQRQLLGSAHAVEVFHREADDTKEQIEKKCQALSAADP-GS
DLFSVQALQRRHEGFERDLVPLGDKVTILGET--AERLSESHP-DATEDLQRQKMELNEA
WEDLQGRTKDRKESLNEAQKFYLFLSKARDLQNWISNIGGMVSSQE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAEDLTGIEILLERHQEHHADMEAKAPTFQALEDFSAELIDS
GHH-ASP--EIEKKLQAVKLERDDLEKAWEQRKKILDQCLELQMFQGNCDQVESWMVARE
NSLRS--DDKG-SLDSLEALMKKREDLDKAITAQEGKITDLEHFAESLIADEHYAKEEIA
TRLQRVLDRWKALKAQLIDERTKLGDYADLKQFYQNLEELEEWISEMLPTACDESYKDPT
NIQANNIISVSFSLQRKYLKHQTFANEVDGRSKQVHDVINLGNSLIERSACDGNEEAMKE
QLERLKEHWDHLLER-TNDKGQKLNEASRQQRFNTSIRDFEFWLS---------------
----EAETLLAMKDQARDLASAGNLLKKHQLLETEMLAREDALKDLNTLAEDLLSSGTFN
VDQIMEKKDNVNKRFLNVQELAAAHHEKLKEAYALFQ-FFQDLDDEESWIEEKLIRVSSQ
DYGRDLQGVQN-------------LLKKHKRLEGELVAHEPAIQNVLDMAEKLK---DKA
AVGQEEIQLRLAQFVEHWEKLKELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAV
RGDSGDTLAATQSLLMKHEALENDFAVHETRVQNVCAQGEDILNKVSYQNKEISSKIEAL
NEKTPSLAKAIAAWKLQLEDDYAFQEFNWKADVVEAWIADKETSL--KTNGNGADLGDFL
TLLAKQDTLDAS--------------LQSFQQERLPEITDLKDKLISAQHNQSKAIEERY
AALLKRWEQLLEASAVHRQKLLEKQLPLQKAEDLFVEFAHKASALNNWCEKM----EENL
---SEPVHCVSLNEIRQLQKDHEDFLASLAGAQADFKCLLELDQQIKALGVPSSPYTWLT
VEV-LERTWKHLSDIIEEREQEL----------------------------QKEEARQVK
--------NFEMCQEFEQNASTFLQWILETRAYFLDG----------------------S
LLKETGTLESQLEANKRKQKEIQAM-----------------------------------
------------------------------------------KRQLTKIVDLGDNLEDAL
ILDIKY-----STIGLAQQWDQLYQLGL--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQAKDTKGVSEETLK------------------EFS
TIYKHFDENLTGR---------------LTHKEFRSC-----------------------
-------LRGL---------------------NYYLPMV---------------------
EEDEHEPKFEKFLDAVDPG-----RKG----------YVSLEDYTA--------------
-FLIDKES----------------------ENIKSSDEIENAFQA-LAEG---KS-----
---------YITKEDMKQALTPEQVS---FCAT-----HMQQYMDPR-GRSHLSGYDYVG
FTNSCFGN---------------------------------------
>gi|31565122|gb|AAH53521.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MDPSGVKVLE-----TAEDIQERRQQVLDRYHRFK
ELSTLRRQKLEDSYR--FQFFQRDAEELEK-----WIQEK--------------------
---------LQIASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGH
FASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTS
EELGQDLEHVEVLQKKFE--EFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDE
VNAAWQR-----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------LKGLALQRQGKLFGAAEVQRFNRDVDETISW-IKEKEQ
----LMASDDFG------------------------------------------------
---------------------------------------------------RDLASVQAL
LRKHEGLERDLAALEDKVKALCAEADRLQQSH-PLSATQIQVKREELITNWEQIRTLAAE
RHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDA
HEDSFKSADESGQALLAAGHYASDEVREK----------------------------LTV
LSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEA
LLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMR
RRAQLADSFHLQQFFRDSDELKSWVNEKMKTATD-EAY-KDPSNLQGKVQKHQAFEAELS
ANQSRID-----ALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKLREA
NQQQQFNRNVEDIELWLYEVEGHLAS------------DDYGKDLTNVQNLQKK------
---------------HALLEAD-VAAHQDRIDGITIQARQFQ-----DAGHF---DAENI
KKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGK-
--------------DLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEG------
--HFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPI
VGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVA-PTDDETGKEL
VLALYDYQEKSPREVTMKKGDILTLLNSTNK-----------------------------
------------DWWKVEVNDRQGFVPAAYVKKL--DPAQSASRENLLEEQGSIALRQEQ
IDNQ--------------------------------------------------------
-------------------------------------YHSLLELGEKRKGMLEKSCKKFM
LFREANELQQWINEKEAALTSEE-VGADLEQVEVLQKKFDDFQKDLKAN-ESRLKDIN--
------------------------------------KVAEDLESEGLMAEEVQAVQQQ--
----------------------------EVYGMMP-RDETDSKTASPWKSARLMVHTVAT
FNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNY-GH
DLASVQALQRKHEGFERDLAALGDKVNSLGET--AERLIQSHP-ESAEDLQEKCTELNQA
WSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDE--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------LAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAH
GHY-ASP--EIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAARE
AFLNT--EDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDIS
SRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPT
NIQ------------SKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKA
RLAALADQWQFLVQK-SAEKSQKLKEANKQQNFNTGIKDFDFWLS---------------
----EVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFD
TSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQ-FFRDMDDEESWIKEKKLLVGSE
DYGRDLTGVQN-------------LRKKHKRLEAELAAHEPAIQGVLDTGKKLS---DDN
TIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVA
SEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGL
NGKVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSL--KTDDYGRDLSSVQ
TLLTKQETFDAG--------------LQAFQQEGIANITALKDQLLAAKHVQSKAIEARH
ASLMKRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENA----EEDL
---TDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFT
MEA-LEETWRNLQKIIKERELEL----------------------------QKEQRRQEE
--------NDKLRQEFAQHANAFHQWIQETRTYLLDG---------------------SC
MVEESGTLESQLEATKRKHQEIRAM-----------------------------------
------------------------------------------RSQLKKIEDLGAAMEEAL
ILDNKYT--EHSTVGLAQQWDQLDQLGM--------------------------------
------------------------------------------RMQHNLE-----------
----------------------QQIQARNTTGVTEEALK------------------EFS
MMFKHFDKDKSGR---------------LNHQEFKSC-----------------------
-------LRSL---------------------GYDLPMV---------------------
EEGEPDPEFEAILDTVDPN-----RDG----------HVSLQEYMA--------------
-FMISRET----------------------ENVKSSEEIESAFRALSSEG---KP-----
---------YVTKEELYQNLTREQAD---YCVS-----HMKPYVDGK-GRELPTAFDYVE
FTRSLFVN---------------------------------------
