>gi|118083463|ref|XP_416550.2|	Gallus gallus
------------------------------------------------------------
--------------------------------------------------MKKFNFR--K
VLDGLTASSPGGSAGGGGAGGGSA------------------------------------
-------HPGGTAGAAG--TP---------------------REEIQETLTSDYFQ----
----------ICKTVRHGFPYLPTALAFDPVQKILAIGTR-----TGAIRILGRPGVDCY
CQHE------SGAAVLQLQFLINEGALVSACADDTLHLWNLRQK---------------R
PAILHSLKFNRE-------------RITYCHLPFQ-SKWLYVGTERGNTHIVNIESFI-L
SGYVI--MWNKAIEL---STKTHP--GPVVHLSDSPRDEGKLLIGYENGTVVFWDLRSKR
ADL---------RAYYD-------------------EAIHSVAWH--HEGKQFMCSHSDG
SLTLWNLKSP---NRPFQTT----IPHGKIQRDGK-KPESC-------KPILKVEYKTCK
NS-EPFVIFSGG----------LSYDKACRRPSLTI---------MHGK---AITVLEMD
HPIVDFLTLCE-TPYPN--EFQE-----------PYAVVVLLEKDLIVVDLTQSNFPIFE
N----PYPIDIH-ESPVTCTEYFADCPPDLIPVLYSVG--AKHKKQ---GYSNKEWPISG
GAWNLGAQT---------YPEIIITGHADGSVKFWDAS---AITLQMLYKLKTSKVFEKQ
KS-----GEGKATAEIVEEDP----------------FAVQMMYWCPESRIFCVAGVSAY
VVIYRFSKHEVNTE------IAS-LEVRLQYEVEDIITPEP--EIIP--QFPD---ASSQ
LPSLKS---LSGSTNTVACEGMMKDSIPCL---SVK------TRPVRMPPGYQADLVIQL
VWVDGEPPQQITSLAVNSAYGLVAFGNCNGLAVVDFMQKTVLL---SMGTLELYGSSDPY
Q-----------------------------------------------------------
------RQPRSPRKSKQFAAD----NFCMRGLSNFYPDLTKRIRTSYQSLTELSDSPVSL
E-LERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKANRRGPGRPPFRKAQSAAC--
-------MEISLPVTTE---ENRENSFSR-SRSSSVSSIDRDSK----EAITALYFMESF
ARKND-SAVSPCLWVGTGLGMVLILSLNLPA----------------SDDLRQ---SE--
PVMVSPS---------------------------GTVLTLKGAVLTFACLDC-TGTLIHP
PYEVWR--DPHSAD---DGEKTRKRK--------LVMH----------------------
-----------------------------------------------------------S
PSSS-QDMGDHQFAVICSEKQAKVFSLPS---QTCLYVHNITETSFLLQADVVT------
------------------------------------------------------------
LCNSVCLACFCANGHIMTL---------------------------SLPSLRPLLDINYL
PVTDM-----------------------------RIARTFC----FSNEGQALYLSSPTE
IQRLTYSQEMCDN----LQDML------------------GDLFTPVET------PEAQ-
NRGFLKG---LFGGSGQA----FDREELFGE------ATAGKASRSLAQHIP--------
-GSGGIEGVRGAAGGVIGDLTR--ARIA--LDERGQK--------------------LGE
LDERTASMM-----------------------------------ASAEAFSKHAHE----
-----------------------VMLKYKD------------------------------
----------KKWYQF
>gi|47221260|emb|CAG13196.1|	Tetraodon nigroviridis
------------------------------------------------------------
-------------------------------------------------KMKKFNIR--K
VLDGLTAASSSSSAT---------------------------------------------
-------AQPGTP------RE---------------------NDLVQETLQSEHFQ----
----------LCKTVRHGFPYQPSSMAFDPVQKILAVGTQ-----TGALRLFGRAGVECY
CQHD------SGAAVIQLQFLINEGALVSALADDSIHLWNLRQK---------------I
PAILHSLKFNRE-------------RITYCHLPFQ-SKWLYIGSERGNIHIVNVESFT-L
SGYVI--MWNKAIEL---STKTHP--GPVVHISDNPMDEGKLLIGFECGVVVLWDLKCKK
ADY---------RYNYD-------------------EAIHSVAWH--HEGKQFVCSHSDG
TLTTWNVRSP---AKPAQII----TPHGKQPKDGK-KPEPC-------KPILKVEYKTTR
AG-DPFMVLSGG----------LSYDTVGRRACLTV---------MHGK---STAVLEMD
YPIVDFLTLCE-TPYPN--DFQE-----------PYAVVVLLEKDLVVIDLGQPGYPIFE
N----PYPLTIH-ESPVTCCEYFADCPAELIPALYSVG--SRQKRQ---CCSKKEWPISG
GNWGQGTQS---------YPEIIITGHADGSVKFWDAS---AFMFQVLYKLKTAKIFERA
RG-----KEEKPSADIVEEDP----------------FAIQTLSWCPESRMLCVAGVSAH
VIVYRFSKQEITTE------VVQLLEVRMQSEFSEVDSPDLGGEQTP--TLPNPGTSSSP
QESDPP---TQPSAGNNSCDGP-RDNIPCL---QVR------SSPLKQSPGYQVELVIQL
VWVSGEPPQPITSLAINSSYGLVVFGNSNGLAVVDYLQKTLLL---NMGTSELYSPSEPY
Q-----------------------------------------------------------
------RQPRSPRKARQPSGDIPPVKSCMSRLSNLYSQSLKKLRSSPVPLCDSSDGPNAS
--EDRCKSPTS-------------------------------------------AKFS--
-------RKISSSGEQKPDLDAKDNSFTR-SRSSSVTSIDRESR----EAISSFHFCESF
PRKTD-AQVSPCLLVGTTQGAVMMVALSLPP----------------TGDPRL---QQ--
PVGISSCGETREALKVKAESCVISNERTPLFSYLGTLVGLKGGILTMALLDA-AGALLPP
TYEPWY--DPNTSDE--EKEKSRRRR--------PA------------------------
-----------------------------------------------------------S
PPSS-QEGQDCQFAVLCSEKQAKVVAMPS---QTRVHKHNITEASFVLRADVVQ------
------------------------------------------------------------
LAGTNCIACFCANGHIMTLRYPLLLPLSPMERYLLLPVRSRMSLCRSLPSLRPLLDVNYL
PLTDM-----------------------------RIARTFC----FSNVGQAMYMTSPTE
IQRVTYSQETCDN----LQEML------------------SELFTPVET------PEAP-
NRGFFKG---LFGGGAQS----LDREDLFGE------TAAGKASRSLAQHIP--------
-GPGNMEGMKSAASGVVGDLAR--ARIA--LDERGQK--------------------LGE
LEERTAAMM-----------------------------------ASADSFSKHAHDVRTR
PVSPAPLHPAGGFLSFPLLFSPQMMIKYKD------------------------------
----------KKWYQL
>gi|108873918|gb|EAT38143.1|	Aedes aegypti
------------------------------------------------------------
---------------------------------------------------MLKFIR--G
------------------------------------------------------------
---------KGQ-------QP---------------------SA-ERQKLQKELFA----
----------FRRTAQHGFPHKPSAVAYDPISRLMAIGTN-----SGIIKVFGRPGVEFY
GQHPA-TTNASDSIVQLLEWIPGSGRLLSLTASNQLILWEPTGT---------------V
LVPIKTLPFDGK-----------LKKISSLCCSYM-KDTVWIGTEGGNVYQFDIKSFS-V
REPVI--YHDVVLEQLPQSYKLNP--GAIESVKQLPNNHNQLLIAYNRGLAVLWDLEACN
VKQ---------SFISP-------------------GHGQSVGLYISPCGTQFTWYHGDG
SFATWDLDSA---IPPENQKY---VPYG---------PDPC-------KAIDRL-IRGKR
GL-CELVVFSGG----------MPRSAYGEHQCVSV--------HCRDG---TKVAFDFT
SKVIDFFVTFN-DEHPE-----Q-----------AEVLVVLLEEELVAYDLTDETIPQIN
V----PYLHSLH-ASAVTCNHLVSGVRPELYEKIVRAG--ESQLSD----YSSKPWPIDG
GLLPETVEEERQ------EYDLLITGHEDGSVKFWNCS---DVCLSPILHVKTAPLFNNS
DE-PFDNHLTTSTEQLDEGEPPFRKAGQFDPYSDDPRLAVKKVQLCPITGTLVVAGTAGN
VVIANFEPSPDQPG------PLKVSTMNLVSDR---------------------------
-------------------DGFVWKGHDQL---KVKRQLLEENTPIQE--GVNVFSVLQV
L-----PPAAVTCTAVQSQWNLVAAGTAHGLVLFDYHTQSPVLHKCTLNPNDLTGAGETL
------------------------------------------------------------
------SRRKSFKKTLRESF------------------------------RRLRKGRSTR
------NNPSA-------------------------------------------------
-------------------QATTPAETRPVERQIEARPVDDGMG----SMVRCLTFAQTY
LTNQ--QHTSATLWSGTNSSCVSVFILNVPPRQQPPPPAQNNEANVDGGDVPP---PK--
PITGVLAK--------------------------EIQLKHRAPVIAISLFDQ-HGVPLEF
----QS--KPGPG---------------------P-------------------------
------------------------------------------------------------
-----------HKVLIASEEQFKVFSLPQLK-PVNKYKLTAHEGARVRRIAFATFMCTLP
A---SHPQASPSKSGPRSPAPAPAPAAESA-----PASGSPSAEALNANPAEPAVAPEVT
KHYEISLLCLTNLGDCLVL---------------------------SIPELKRQLNAAAV
RREDI-----------------------------NGISSLC----FTNHGEALYMMSSSE
VQRITLSTSK-------IVSPT------------------GYIELEDWSQADQEEPEQ--
----------AVEAEETPATPDAEAPAAAGK------TFDVSSPLSVAVTSI------NG
TGAAGDGLTNGVGSGDDASPNK--AANETITSSIGDITIDSVRDHLNSTTTTLCSTTTEE
IVGRLSVLS-----------------------------------THSNNVASSAKTTDVT
TLNSSNIKDLKHIGDSTETASNSVIIKSVITTVKHGTSHVNGEHNSTTTTESSKTVSTGG
GTGGTTVSLLRKESQF
>gi|110760680|ref|XP_392864.3|	Apis mellifera
------------------------------------------------------------
--------------------------------------------------MIQRILRMNS
A-----------------------------------------------------------
-------ESTGR-------YP---------------------NVIDTESLEDDQWPRHGA
RESGLLWSCMVCVTVQHGFPNKPTALAWDPSLRLMIIGTA-----SGAIKVFGRPGVEFY
GQHTI---ESGENAVTKIVALPNEGRVVSLCDDNSLHLWEINES---------------S
VVETKSLSLEGK-----------LKKISAMCLESS-GEHLLLGTEGGNIYLLNLKTFV-V
PDNII--YQDVVMQNVPDDYKKNP--GAVEAIAEQPGHPDNILIGYNRGLMVLWNKATPG
AQQLMGLFSRTQTFVST-------------------QQLESVHWV---SETRFVSSHNDG
SYAFWSDSSD---SMLEST-----TLYG---------PFPC-------KAITKI-HHCKN
RL-KELVLFSGG----------MQRASYGDRHTITV---------MVKG---KHVVFDFT
SKVIDFFTVFS-KEEDGKDIPAS-----------PEALIVLAEEEIVAIDLTNPEWKMMA
L----PYLVSLH-ASAVTCSQHVPNVPEELWDSIIAAG--KAQTEH---LYSDKSWPIDG
GIILNQKSGNDKPK----TRELLLTGHEDGTVRFWNAS---DVALTPLYKYNTSILFTGE
HL----DVLEQPPEDDEDEWPPFRKVGTFDPYSDDPRLAVKKVLLCPLSSTLVVAGTAGH
IITATISSEPVNKE-------IKAVTMNIVNDR---------------------------
-------------------DGFVWKGHDHL---PAR------TTSISFAVGFQPQSLLQL
Y-----PPAAVTALAIHSEWGLLAAGTAHGLAVFDYTRGKAVNVKCTLNPNDLSGASDTP
I-----------------------------------------------------------
------SRRKSFKKSLRESF------------------------------RRLRKGRSQR
--RTNANSPTR-------------------------------------------------
---------NTTSEKKKETGDLSPVELKPVERQVEARPVDDALG----SMVRCLYFARSY
IISM--QNTTPTLWAGTNNGTVYVFTLAIPA-----------------GVRRT---EE--
DVNCTLGK--------------------------EIQLKHRAPVIAITILDG-SSVPLPE
PFEAEK--GVSPG---------------------PDMA----------------------
-----------------------------------------------------------S
P----------HRVVIASEEQFKIFNLPSLK-PYCKYKLTAHEGSRVRKTGFAKFTCPME
P----------------------------------AG-----------------------
THEETCLLCLTNLGDCLVL---------------------------SIPELRRQLNAAAI
KKEDI-----------------------------NGISSLT----FTKAGEALYLYSSSE
LQRISLSASK-------VTKAN------------------CALNLPPNARSF---PETNN
EDTQEEG---IIEGTPETE----------GE------TTQGSQPVTMQRITE-NGVVGST
GGEESPKESPLQPAASTNDVNA--EDDRQDLSSIGDITIDSVKDHLLNATS------SEE
LHNRLAGLKMEVTSRTSEISTQNQSLVLKTTTVVSQTTN----NTTANGEIETSQTNETQ
QVNSTTVEREIRSGTETTTTHATITLPSNV------------------------------
----------EVIKRH
>gi|62751433|ref|NP_001015691.1	Xenopus tropicalis
------------------------------------------------------------
---------------------------------------------------MKRFLR---
------------------------------------------------------------
-------------------SG---------------------HDSVRERLKRDLFQ----
----------FNKTVEHGFPHQPSALGYSDCLSLMAIGTR-----SGALKVYGSPGVEFM
GLHD------ENNSVTKISFIPDQCQLVTVLDDNSLHLWSFPHHDGVS-----------E
LQEEKKFTLRGPPG-----SPPSVTQIKVLLPHSS-GEKLYVGTEGGSVFILELPSLRVL
EEKTV--GHEAALQGLPDEYSSRRAFESVEALQENPRNPDQLLIGYSRGMMVTWDLVKGR
SVQ---------YFLGK-------------------QQLENVFWC--RDGKQIVSCHSDG
GYNQWEVSNELVQVSPKESK----VPYG---------PFRC-------KAISKITWHTTR
RSRSPYVVFQGG----------MPMASYGDRHIISV---------VHGN---QQTAFDFT
SRIIDHVVIAN-PDPSA--EYDD-----------PRALLVLVEEELVMIDLQSPGWPVIQ
C----PYLISLH-CSAITCSHHISSIPLKLWERIISAG--RKQNTQ----YSNMPWPIDG
GVNLAPAPF---------QRDLLLTGHEDGTVRFWDAS---GICLQLMYKMSTVSVFQTE
SD-----HNDNVNSNEEEEWPPLRKVGSFDPYSDDPRLGIQKIYMCKYSGYLSVAGTAGQ
VLVMEL-NDEAAEH------VVDETLVDLLQEQ---------------------------
-------------------EGYRWKGHKRL---HAR------EDPVRFPPGFQPFALVQC
Q-----PPAAVTSLALHSEWRLLAFGTSHGFGLYDFQQKRQVMAKCTLHASDQMALEGPL
------------------------------------------------------------
------SRVKSLKKSLRQSF------------------------------RRIRRSQVNK
------RRPGP-------------------------------------------------
-------DRVQEANARFEQEALQEMELAPVQRRIEARSAEDSFT----GFVRTLYFADTY
LRDS--SRHTPSLWAGTNGGTVYAFSLRVPP-----------------TERRM---EE--
AVAATQAK--------------------------EIQLMHRAPVVGILVLDG-HSVPLPE
PLEAAH--DLSKS---------------------PDMQ----------------------
-----------------------------------------------------------G
S----------HQLLVTSEEQFKVFTLPKVS-SKLKLKLTATDGCRVRKMTVCTYGSCKS
E-----------------------------------------------------------
EHSENHLTILTNLGDIQVV---------------------------SLPHLKPQVRYDCI
RKEDV-----------------------------SGIASCV----FTKHGAGVLSNLPSE
LERFSLST--------------------------------CWLVAPRARVDP---PEPPR
NSRLRRG---------------------------------GSTDQPTDRSR---------
-SSGTDHTGGQRAQGTLMEHAL--LNDEKMLKEI-----------------------QST
LEGTRISYS-----------------------------------ERSSRQMSVGHR----
-----------------------LINGAAE------------------------------
----------------
>gi|126311182|ref|XP_001381100.	Monodelphis domestica
------------------------------------------------------------
--------------------------------------------------MKKFNIR--K
VLDGLTAGSSSSSSQQQ-QQQQQQQ-----------------------------------
-------QQPGS-------RE---------------------NE-VQETLQSEHFQ----
----------LCKTVRHGFPYQPSALAFDPVQKILAVGTQ-----TGALRLFGRPGVECY
CQHD------SGAAVIQLQFLINEGALVSALADDTLHLWNLRQK---------------R
PAILHSLKFSRE-------------RITFCHLPFQ-SKWLYVGTERGNIHIVNVESFT-L
SGYVI--MWNKAIEL---SSKSHP--GPVVHISDNPMDEGKLLIGFESGTVALWDLKSKK
ADY---------RYTHD-------------------EAIHSVAWH--HEGKQFICSHSDG
TLTIWNVKSP---TKPVQTI----TPHGKQLKDGK-KPEPC-------KPILKVEFKTTR
SG-EPFIILSGG----------LSYDTVGRRPCLTV---------MHGK---STAVLEMD
YSIVDFLTLCE-TPYPN--DFQE-----------PYAVVVLLEKDLVLIDLAQNGYPIFE
N----PYPLSIH-ESPVTCCEYFADCPVDVIPALYSVG--ARQKRQ---GYSKKEWPISG
GNWGLGTQS---------YPEIIITGHADGSIKFWDAS---AITLQVLYKLKTSKVFEKS
RN-----KDDRLNTDIVDEDP----------------YAIQIISWCPESRMLCIAGVSAH
VIIYRFSKQEVTTE------VIPMLEIRLLYEINDVDSPEL--EQVP--PLPTPVGGSNP
QPIPPQ---SHPSTSSSSSDGL-RDNVPCL---KVK------SSPFKQSPGYQAELVIQL
VWVGGEPPQQITSLAVNSSYGIVVFGNCNGIAMVDYLQKAVLL---NLGTIELYGSNDPY
R-----------------------------------------------------------
------REPRSPRKSRQPSG---------------------------AGLCDINEGTIVP
--EDRCKSPTS-------------------------------------------AKMS--
-------RKLSLPTELKPDLDIKDNSFSR-SRSSSVTSIDKESR----EAISALHFCETY
TRKTD-SSPSPCLWVGTTLGTVLVIALNIPP----------------GGEQRL---LQ--
PVIVSPS---------------------------GTILRLKGAILRMAFLDN-TGCLVPP
AYEPWR--EYNVSEEKDEKDKLKKRR--------PVSV----------------------
-----------------------------------------------------------S
PSSS-QEISENQYAVICSEKQAKVISLPT---QNCAYKQNITETSFVLRGDIVA------
------------------------------------------------------------
LSNSICLACFCANGHIMTF---------------------------SLPSLRPLLDVYYL
PLTNM-----------------------------RIARTFC----FTNNGQALYLVSPTE
IQRLTYSQETCEN----LQEML------------------GELFTPVET------PEAP-
NRGFFKG---LFGGGAQS----LDREELFGE------SASGKASRSLAQHIP--------
-GPGGIEGVKGAASGVVGELAR--ARLA--LDERGQK--------------------LGD
LEERTAAML-----------------------------------SSADSFSKHAHE----
-----------------------MMLKYKD------------------------------
----------KKWYQF
>gi|395083|emb|CAA51715.1|	Drosophila pseudoobscura
------------------------------------------------------------
---------------------------------------------------MLKFIR--G
------------------------------------------------------------
---------KGQ-------QP---------------------TA-ERQRLQKDLFA----
----------YRKTAQHGFPHKPSALAYDPVDQSSWRGTQ-----TGAIKVFGQPGVELY
AQHTLVNNSAAELNVQLLEWVYGTGRILSLTAANQLILWEPVGT---------------T
LVPIKTLPFDGK-----------LKKVSSLCCSLN-KDLLWIGTEGGNIYQLDLKSFT-I
REPVI--YHDVVLEQVPPTYKLNP--GAIESIRQLPNSLNKLLIAYNRGLCVLWDMQTSA
VER---------AYIAP-------------------GHGQSVGLSVNSTGTEFSWYHADG
SYATWSIDNG---EPPQNVNY---VPYG---------PDPC-------KSINRL-YKGQR
GT-NDVIVFSGG----------MPRSAYGDHNCVSV--------HVSDG---QKVCLDFT
SKVIDFF-----VTYKE--GSDD-----------VEVLIVLLEEELCAYDLTDPSILSIK
A----PYLHSVH-ASAVTCNYLASQVTQGVYERILRAG--DEQDID----YSSIDWPITG
GVLTDDSVESDEGRKLVKDYEILLTGHEDGTVKFWDCT---GVLLKPIYNFKTASIFGNE
HEYREDGAADISAEQLDEGEPPFRKAGLFDPYSDDPRLAVKKIAFCPKTGQLVVGGTAGQ
IVIADFDTAAEDQS------SLKYNSMNLVSDR---------------------------
-------------------DGFVWKGHDQL---NVRANLLEDNAVPLTENGVNITGVLQV
L-----PPASITCMALEANWGLVSGGTAHGLVLFDFKNFVPVFHRCTLNPNDLTGAGEQL
------------------------------------------------------------
------SRRKSFKKSLRESF------------------------------RKLRKGRSTR
------NNPTN-------------------------------------------------
-------------------QVPTTLEARPVERQIEARCTDDGLG----SMVRCLLFAKTY
VTNV--NITSPTLWSATNASTVSVFLLHLPP-----AQTAATTVPPASGNVPPQ-ASR--
RISAQLAK--------------------------EIQLKHRAPVVGISIFDQ-TGSPVDQ
----FNAGENGSP---------------------P-------------------------
------------------------------------------------------------
-----------HRLLIASEEQFKVFSLPQLK-PINKYKLTANEGARIRRIHFGSFTCRIS
PELLQSLHSGSPTKSVRSHGEG-------------DGAGNVSATSAAGRGD---------
LYHEMALICLTNMGDIMVL---------------------------SVPELKRQLNAAAV
RREDI-----------------------------NGISSLC----FTNDGEALYMMSSSE
LQRIALSTSK-------VLQPT------------------GIVEVEPLE------SEDNE
TAS-------LVNDGNESDKDGERNKELANT------ASDTQPPVATLRAKP----LELN
ADRSSLHLTNGISNSNSPNRAN--ETIT---SSIGDITVDSVRDHLNTTTTTLCSTTTEE
TVGRLSVLS-----------------------------------TQTNQATTTVNMKDIP
DINIPNLMDLASKSNTTETSTSSVVIKSVITSISHEKTNGDGNVTTKTTA----------
----------HEESQF
>gi|115715385|ref|XP_783870.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
----------------------------------------------MASRMRKLFHR---
------------------------------------------------------------
-------QNAGA-------IE------------------------ERRKMRKELFA----
----------FNKTVEHGFPNKPTALAYDPKLNIFAIGTS-----NGVIKIYGAPGVEFM
GIHS------GDFSVSKLFFLPAQGRIISLLDDNSLHLWEIN------------------
-------------------------------------------LKDGGSTMEEVKNFM-I
EGRV------------PDDFKVNP--GAVEAIAQHPSDKDRLLIGYNRGLMIIWRQSELM
LEA---------SFVG--------------------HQIESLCWH--RDGTHFTSSHNDG
SYQVWKVSGA---SSPAKEPL---VPYG---------PFPC-------KAIPKILYLTTK
S--EPFTIFSGG----------MPRASYGDRHVVTV---------IQDKT--QHVVFDFT
SKVIDFFTMSN-VNDED--EFDE-----------PHSLVVLVEEEIVFIDLQTKGWPTFQ
L----PYLSSLH-ASAITSSNYICNVPSQLWEKIQEVG--EHQQQN---VMSTRDFPVIG
GKNLVEPPA---------YHDLLLTGHEDGSIRFWDAS---ASAMKYLYQVNVAQLFTAE
GG---EQNGSPGVVEAEEEWPPFRKVGNFDPFSDDPRFGVQKVVLCPQSGTLVAGGTAGQ
VVVMKMGEDEEEKK------TIEVVQAKIVVD----------------------------
-------------------DKFVWKGHEAL---PVR------EEPFKFPRGFQVELVAQA
H-----PPAAITALAFQSTWGIIAFGTSHGFSLIDTTLKRLIVSHCTLNPHDLSVTGEH-
M-----------------------------------------------------------
------SRRMSLTKSLRASL------------------------------RRVRQKRGTT
KPRKQRERRSN------------------------------------DTGGKVIEGSD--
-------NTPTTPEKESRGRGFDDADLVPIERKIEARSEDPKVS-----MVRYVYFANTF
VRDA--HTATPSLWVGTNAGVIYIYSLGVPT-----------------GENRL---QG--
NVVAEISK--------------------------EIKLKHGAPINSMVVVDS-DNNPLPD
PIEVQH--ECAKP---------------------PNMS----------------------
-----------------------------------------------------------G
-----------HNLIVCSEEQFKVFALPSLK-PRYKTKLTAMDGSKVRKVAFINYRSRNN
D-----------------------------------------------------------
SYSENHISCLTNQGELGIY---------------------------SIPHLKRQDHYQAL
RRENV-----------------------------TGIASLL----FTPRGEGMYLLSPSE
FER---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------
>gi|149758229|ref|XP_001488258.	Equus caballus
------------------------------------------------------------
--------------------------------------------------MSRGRLA--E
GRVGVCGV----------------------------------------------------
-------LLPGGTGGAKARRG---------------------ACLGNWRRAKDPWA----
----------WSQTVEHGFPNQPSALAFDPELRIMAIGTR-----SGAVKIYGAPGVEFT
GLHR------DTTTVTQMHFLPGQGRLLTLLDDSSLHLWEILHHDGCA-----------H
LEEALSFQPPSRPGFDGASGLPSLTRVTVVLLVAA-GDMAALGTEGGSVFFLDVPTLTLL
EGQTL--GPDEVLRSVPDDYRCGKALGPVEALEGHLRDPTKILIGYSRGLLVIWNQAAQC
ADH---------IFLGN-------------------QQLESLCWE--RSGSTLVSSHSDG
SYAIWSADTG---SSPTTQPMVATTPYG---------PFPC-------KAINKILWRNCE
SG-GHFIIFSGG----------MPRASYGDRHCVSV---------LQAE---TLVTLDFT
SRIIDFFTVHS-TRPED--EFDQ-----------PQALAVLLEEELVVLDLQTPGWPAVP
A----PYLAPLH-SSAITCSAHVANVPAKLWARIVSAG--EQQSPQP--ASTALSWPITG
GRNLAQEPS---------QRGLLLTGHEDGTVRFWDAS---GVALRPLYKLSTAGLFQTD
CE-----HADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVVLCKYTAQMVVAGTAGQ
VLVLELSDVPSEQA-------VSVSSVDLLQDR---------------------------
-------------------EGFTWKGHERL---SPR------TGPLPWPTGFQPRVLVQC
L-----PPAAVTAVTLHAEWSLVAFGTSHGFGLFDYQRKCPVLARCTLHPNDSLAMEGPL
------------------------------------------------------------
------SRVKSLKKSLRQSF------------------------------RRIRKSRVSG
--KKRAANANS-------------------------------------------------
-------KLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLS----GVVRCLYFADTF
LRDA--AHHGPTMWAGTNSGSVFAYALEVPT-------------AVAGGEKRP---ER--
AVEAVLGK--------------------------EVQLMHRAPVVAIAVLDG-RGRPLPE
PYEASR--DLAQA---------------------PDMQ----------------------
-----------------------------------------------------------G
G----------HAVLIASEEQFKVFTLPKVS-AKTKFKLTAHEGCRVRKVALATFASVAC
E-----------------------------------------------------------
DYAETCLACLTNLGDVHVF---------------------------SVPGLRPQVHYSCI
RKEDI-----------------------------SGIASCV----FTRHGQGFYLISPSE
FERFSLSARN-------ITEPL------------------CSLDISWPG------DAARA
SYGLRES---------------PKLSQANGTPGIVLAPRSHDGSPSPVRSM---------
-GTDTPQPPEATLSPMSIDSAT--SADTT-LDTTGDVTVEDVTDF------------LGS
SEESEKNLR-----------------------------------NLAEDEARACA-----
-----------------------ILIK---------------------------------
----------------
>gi|45185876|ref|NP_983592.1|	Ashbya gossypii
------------------------------------------------------------
-------------------------------------------------MFKSRRLK--N
VTNALKSV----------------------------------------------------
------------------------------------------RGGDSGHLNGKLFE----
----------LTEVCRSGVGGNVVAMAFDPVQSLLAVATE-----TGEVHVYGKQQVEVV
FTLK-------IKAAKAMRFVKGV-YLVVVDRSDGLTVISLH-----------------R
KCILASIYAPGK--------------ITAVEVDPS-VDWMLLGLQNGSVIVYDVDRDV-L
SPYMI--ENLQKSTV---FPRERS--SPVVSIQWHPRELGTLLIAYER-VVVTYSLVENC
IKQ---------QFVYELPPGAPGGDPGADINKPRAPFVVQALYH--PNGLHILTVHADN
SLVFWDANNG---ELIQARTLFDMDVHVPGSYENL-NGMRN-------DRIKKVAWICDA
DPEKTSLLIAGGTAPHGTETFGLTMLDFGTTPKYSVTSYEKMSHYYSNPVRQKSFMLPSE
SSIVDFLPLPRKSPYFA--GNHD-----------PSLILVLLANGELDTLLYPSGNVTHR
AS---LFPQSLSWVRPTVTVATAANIPTKQWLGMMSCT------------YN-KDHFLKG
GAQVRKTARRHY------GRTAFITGHSNGSVRIWDASHR-ELEETSVFNINVAQALGTT
DN-----------------------------------VAVEHVSFAAETAELAVSVSSGD
VLLYKFQDNPMFNP------NGVAGELDGSFAR---------------------------
-------------------LGIGNMSELLV---DVS-----DRAPSHMKVGFCPLSAVRA
------NLGKVSAVT-NSNIGFVAVAYEDG----------------SLLVIDRRKPAVIY
M-----------------------------------------------------------
------ENLRRLK-----------------------------------------------
------------------------------------------------------------
-----------------------------------------LKS----AYVKSIEFSIMA
FRDD--GYSSILLFCGTDAGELLIFKVLPEL-------------------------SG--
RFVVNFVD--------------------------NLSLHDQSPILKVETLSIEHASSCQA
SIGKMQ--ELKTG---------------------TIIR----------------------
-----------------------------------------------------------G
C------------VVLTSGSGIQLITDWAVK-PTCK---SFSVPLATTGCAFVPYKGAKD
Q-----------------------------------------------------------
LLTGIILIALQINSEIKLL---------------------------SLPDLKELKTLVPP
TTPQA-----------------------------QYLRNSS----VLHNGDLMLRVGPAE
AILFSILPGQSQDNTSAADAET------------------DVLYNPKLHF-----PARPH
VGALQ-----WARGSMLVKC--DELAELLSG--------GNRPPPKYPESKL--------
-SSVAHSASSASPSSEADQETQ--YQAPMKHSQRGNASWRSFTKSVQNG--------IDY
LEDSVNDYA-----------------------------------AAANKSMNDALEQTRK
-----------------------DIVKGAF------------------------------
----------KSKMGI
>gi|28571169|ref|NP_572819.3|	Drosophila melanogaster
------------------------------------------------------------
--------------------------------------------------MKKFTFK--G
VLDGFRQSV---------------------------------------------------
-------QPQAT-------RQ---------------------EQEIQEQLKADHFT----
----------LKKTFRHGFPYSPTSFAFDPVQKLLAIGDK-----SGYIRILGRPGVDAH
AKHE----GESECAVLFAQFLVNEGALVTVTADDTIHLWSIRQK---------------T
PRIVQSLKFQRE-------------RVTCIHLPVG-SKWLYVGTEKGNIHVVHIDTFA-L
SGYII--NWNKAIEV---VRTSHP--GAVIALCDNPLDANKLLIAFECGLLVLWDLKAKC
AEL---------RWQAA-------------------EAVKSLAWH--YEGKYFVSSHTDG
SICSWPTKPQ---AKPQSQV----CPHAKINKDG--NAEKC-------KPIYKVDLKSSA
TG-ETFTIFSGG----------MPSEKGSKSNCITV---------MVGK---ATTVLEME
HAVCDFITLCE-NPWPC--ETQE-----------PYAIAVLLQYDLVLIDLLTPGFPCFE
S----PYPMDLH-ESPVTCCTYLTDCPSDLVPAFYSVGRTTTSKKS---CFSEREWPISG
GEWSPASCS---------YSEIVITGHQDGSLKFWDSG---AGTLQILYKLKTAKMFEKP
RS-------HVAHSHPESDNP----------------LAVHLIFLCSESRRLCVAGAMGQ
VMLFKFRKVESTSE-------VLVLEIPILYEN-----------------------FDDI
YGTSPECDFLTGHQVQKAESSDSDKTAECSL--KVR------NGAQRKPPGFQSQLVCLT
TGPNR-RNVQVTSLCISSSYGLMAYGTEYGLVIIDIIQKICLL---SVACPDLYGAHDPY
S-----------------------------------------------------------
------RTPKSPKRIENK------------------------------------------
--EEQSRSPSS-------------------------------------------------
-----------------DQVNKLDGTFSR-SRSSSMSSIDMSSS----ESVTCLAFIESY
AKRNDILTLVPTLWIGTSFGSILTLFITMPE-----------------RDVRK---SQ--
PVLITING--------------------------GPVVRLKGSITSMSFLDS-YGSIIPY
TFETWR--DEKRDNKDRTPTKSSSRTS-------PTFTPTTANTLSNTSVAGGASAGGGA
GGGGGAGGGAASGGAAAGGPAGGGAGAGSAAGAAGGVGSGVTSGGGMSSSSASSSGISGS
VSTGLETLTDRQYIVIASEKQTKVFDVAN---QCCINRIQLSEMDFAVKAETIT------
------------------------------------------------------------
MKDGSCLATYLSNGHLMVH---------------------------SLPSLKLLLDTDFL
PLMELSFQTKCKQGIVDPMLSIWGQQIIVHEDTTQISKIFC----FSHKGHGLYMASPTE
IQKFTISSEFCQF----ILEMM------------------GELYTVHEM------PEQP-
KEGFFKG---LFGGGAKL----LDREELFGE-------QSGKPNRSVARHIP--------
-GP-NLEQLGQRASTAASEISR--AHQL--AMERGEK--------------------LNL
LEERAERMA-----------------------------------NTAQDFSGTAHQ----
-----------------------LMLKYKD------------------------------
----------KKWYQL
>gi|149409984|ref|XP_001507080.	Ornithorhynchus anatinus
------------------------------------------------------------
--------------------------------------------------MRKFNIR--K
VLDGLTAASSSSSSSSSSQQQQQQQ-----------------------------------
-------HQPAS-------RE---------------------SE-VPETLQAEHFQ----
----------LCKTVRHGFPYQPSALAFDPVQKILAVGTQ-----TGALRLFGRPGVECY
CQHD------SGAAVIQLQFLINEGALVSALADDTLHLWNLRQK---------------R
PAILHSLKFTRE-------------RITFCHLPFQ-SKWLYVGTERGNIHIVNVESFT-L
SGYVI--MWNKAIEL---SSKSHP--GPIVHISDNPMDEGKLLIGFESGTVALWDLKSKK
ADY---------RYTHD-------------------EAIHSVAWH--HEGKQFICSHSDG
TLTIWNVRSP---TKPIQTI----TPHGKQLKDGK-KPEPC-------KPILKVEFKTTR
SG-EPFIILSGG----------LSYDTVGRRPCLTV---------MHGK---STAVLEMD
YSIVDFLTLCE-TPYPN--DFQE-----------PYAVVVLLEKDLVLIDLAQNGYPIFE
N----PYPLTIH-ESPVTCCEYFADCPAELIPALYSVG--VRQKRQ---GYSKKEWPISG
GNWGLGTQS---------YPEIIITGHADGSLKFWDAS---AITLQVLYKLKTSKVFEKS
RS-----KEERPSTDIVDEDP----------------YAIQIISWCPESRMLCIAGVSAH
VIIYRFSKQEVTTD------VIPMLEIRLLYEINDVDSPES--EQVP--PLPTPGGGSNP
QPPAPQ---SRPSTSSSSSEGL-RDNVPCL---KVK------SSPLKQSAGYQIELVIQL
VWVGGEPPQQITSLAVNSSYGLVVFGNCNGIAMVDYLQKSVLL---NLGTIELYGSNDPY
R-----------------------------------------------------------
------REPRSPRKSRQPSG---------------------------AGLCDINEGTVVP
--EDRCKSPTS-------------------------------------------AKMS--
-------RKLSLPTELKPDLDVRDNSFSR-SRSSSVTSIDKESR----EAISALHFCETF
TRKAD-SSPSPCLWVGTTLGTVLVIALNLPP----------------GGEQRL---LQ--
PVIVSPS---------------------------GTILRLKGAILRMAFLDT-IGCLVPP
AYEPWR--EHNVPEEKDEKDKLKKRR--------PVSV----------------------
-----------------------------------------------------------S
PSSS-QEISENQYAVICSEKQAKVISLPT---QNCAYKQNITETSFVLRGDIVA------
------------------------------------------------------------
LSNSVCLACYCANGHIMTF---------------------------SLPSLRPLLDVYYL
PLTNM-----------------------------RIARTFC----FTNNGQALYLVSPTE
IQRLTYSQETCEN----LQEML------------------GELFTPVET------PEAP-
NRGFFKG---LFGGGAQS----LDREELFGE------SASGKASRSLAQHIP--------
-GPGGIEGVKGAASGVVGELAR--ARLA--LDERGQK--------------------LGD
LEERTGAML-----------------------------------SSADSFSKHAHE----
-----------------------MMLKYKD------------------------------
----------KKWYQF
>gi|119901619|ref|XP_617776.3|	Bos taurus
-------------------------------MLSSPAPPRPSCRHRRGQRCNRGCPLLLG
AGLPPSPHTPTRASSSASSVEAALGPGRFPPRLGTPLTSAPGVRGSPAATMRKFNIR--K
VLDGLTAGSSSAS-----QQQQQQQ-----------------------------------
-------HPPGN-------RE---------------------PE-IQETLQSEHFQ----
----------LCKTVRHGFPYQPSALAFDPVQKILAVGTQ-----TGALRLFGRPGVECY
CQHD------SGAAVIQLQFLINEGALVSALADDTLHLWNLRQK---------------R
PAILHSLKFCRE-------------RVTFCHLPFQ-SKWLYVGTERGNIHIVNVESFT-L
SGYVI--MWNKAIEL---SSKSHP--GPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKK
ADY---------RYTYD-------------------EAIHSVAWH--HEGKQFICSHSDG
TLTIWNVRSP---AKPVQTI----TPHGKQLKDGK-KPEPC-------KPILKVEFKTTR
SG-EPFIILSGG----------LSYDTVGRRPCLTV---------MHGK---STAVLEMD
YSIVDFLTLCE-TPYPN--DFQE-----------PYAVVVLLEKDLVLIDLAQNGYPIFE
N----PYPLSIH-ESPVTCCEYFADCPVDLIPALYSVG--ARQKRQ---GYSKKEWPING
GNWGLGAQS---------YSEIIITGHADGSIKFWDAS---AITLQVLYKLKTSKVFEKS
RN-----KDEKPNTDIVDEDP----------------YAIQIISWCPESRMLCIAGVSAH
VIIYRFSKQEVITE------VIPMLEVRLLYEISDVETPEG--EQAP--PLPTPVGSANP
QPIPPQ---SHPSTSSSSSDGL-RDNVPCL---KVK------SSPLKQSPGYQTELVIQL
VWVGGEPPQQITSLAVNSSYGLVVFGNCNGIAMVDYLQKAVLL---NLGTIELYGSNDPY
R-----------------------------------------------------------
------REPRSPRKSRQPSG---------------------------AGLCDISEGAVVP
--EDRCKSPTS-------------------------------------------AKMS--
-------RKLSLPTDLKPDLDIKDNSFSR-SRSSSVTSIDKESR----EAISALHFCETF
TRKTD-SAPSPCLWVGTTLGTVLVIALNLPP----------------GGEQRL---LQ--
PVIVSPS---------------------------GTILRLKGAILRMAFLDS-TGCLVPP
AHEPWK--EHNVPEEKDEKEKLKKRR--------PVSV----------------------
-----------------------------------------------------------S
PSSS-QEISENQYAVICSEKQAKVISLPS---QNCAYKQNITETSFVLRGDIVS------
------------------------------------------------------------
LSNSICLACFCANGHIMTF---------------------------SLPSLRPLLDVYYL
PLTNM-----------------------------RIARTFC----FTNNGQALYLVSPTE
IQRLTYSQETCEN----LQEML------------------GELFTPVET------PEAP-
NRGFFKG---LFGGGAQS----LDREELFGE------SSSGKASRSLAQHIP--------
-GPGGIEGVKGAASGVVGELAR--ARLA--LDERGQK--------------------LSD
LEERTAAML-----------------------------------SSADSFSKHAHE----
-----------------------MMLKYKD------------------------------
----------KKWYQF
>gi|148231603|ref|NP_001089126.	Xenopus laevis
------------------------------------------------------------
--------------------------------------------------MMKFRFR--R
------------------------------------------------------------
---------QGH-------DP------------------------QREKIKQELFA----
----------FNKTVEHGFPNQPSSLAFDPLLRIMAIGAK-----SGAVKIYGAPGVEFT
GLHK------DMATVTQMNFLPGQGRLLSLLDDNTIHLWELQQKDGSS-----------Y
LEETHSFILPGK------PGSPPSVTPSDCHTDNGLCEVAGLGTEGGGVYFIQIPSLKLL
EEKTL--LQDEIIKSLPEEYRCGKTLGPVESLQEHPCQRGKILIGYSRGLVVLWDQEARK
MEH---------LFLGN-------------------QQLESVFWG--RKGSSFISSHSDG
GYMVWEAGSD---SSTTSQPVTSKIPYG---------PFPC-------KAINKIQWRSSS
SG-NPFIIFSGG----------MPRASYGDRHCVTI---------LQGQ---NLVTLDFT
SRVVDFFTVCP-LKSED--DSDN-----------PTALVVLVEEELVVIDLQTPGWPTIP
T----PYLAPLH-SSAITCAYHISNVTTKLWERIISTG--EQQNPQ----LSSVNWPIDG
GRNLAEEPA---------QRGLLLTGHEDGTVRFWDAS---GVALRPLYKLSTAGIFRQT
ATTM--RPNESFNQSNDEEWPPFRKVGCFDPYSDDPRLGIQKIALCKYSGKLLVAGTAGQ
VLVMDL-NDEKSEH------TINVATVDLLQER---------------------------
-------------------EGFTWKGHDRL---TPR------NGSLFFQSGFQTTMLVQC
M-----PPAAVTAIALHSEWNLVAFGTSHGFGLFDYHRRSPVLARCTLHPNDSLAMEGPL
------------------------------------------------------------
------SRVKSLKKSLRQSF------------------------------RRIRKSRVSG
KKRPNTGSPPS-------------------------------------------------
-------RLQEANAQLAXQAGPHDLDIAPVQRRIEPRSADDSLS----GVVRCLYFADTF
LRDA--VHRGPTMWAGTNSGSVFAYALEVPS-----------------REKLS---ER--
SAEALLGK--------------------------EIQLMHRAPVVSIAVLDG-RGNPLPE
PFEVSQ--DLAKA---------------------PDMQ----------------------
-----------------------------------------------------------G
T----------HSVLISSEEQFKVFTLPKVS-AKTKFKLTAHEGCRVRKVALANFTSSSS
D-----------------------------------------------------------
DYSENCLACLTNLGDIHVF---------------------------TVPGLRPQVRYDCV
RKEDI-----------------------------SGIASCV----FTKYGQGFYLISPSE
FERFSLSAKN-------ITEPV------------------CLVEFDR--------PHDPS
HVGHKATPSPKANGTHILR--DLDANQKATE-----------------------------
-GNAGERMPEFSPSPLDSPLNS--MDLT--LDTTGDITVEDVRDI------------LGA
TDEAEKNMK-----------------------------------NSADDPLPPE------
-----------------------ILIK---------------------------------
----------------
>gi|30387644|ref|NP_848035.1|	Rattus norvegicus
------------------------------------------------------------
--------------------------------------------------MRKFNIR--K
VLDGLTAGSSSAS-----QQQQQQQ-----------------------------------
-------HPPGN-------RE---------------------PE-IQETLQSEHFQ----
----------LCKTVRHGFPYQPSALAFDPVQKILAVGTQ-----TGALRLFGRPGVECY
CQHD------SGAAVIQLQFLINEGALVSALADDTLHLWNLRQK---------------R
PAVLHSLKFCRE-------------RVTFCHLPFQ-SKWLYVGTERGNIHIVNVESFT-L
SGYVI--MWNKAIEL---SSKSHP--GPVVHISDNPMDEGKLLIGFESGTVVLWDLKSKK
ADY---------RYTYD-------------------EAIHSVAWH--HEGKQFICSHSDG
TLTIWNVRSP---TKPVQTI----TPHGKQLKDGK-KPEPC-------KPILKVEFKTTR
SG-EPFIILSGG----------LSYDTVGRRPCLTV---------MHGK---STAVLEMD
YSIVDFLTLCE-TPYPN--DFQE-----------PYAVVVLLEKDLVLIDLAQNGYPIFE
N----PYPLSIH-ESPVTCCEYFADCPVDLIPALYSVG--ARQKRQ---GYSKKEWPING
GNWGLGAQS---------YPEIIITGHADGSIKFWDAS---AITLQVLYKLKTSKVFEKS
RN-----KDDRQNTDIVDEDP----------------YAIQIISWCPESRMLCIAGVSAH
VIIYRFSKQEVVTE------VIPMLEVRLLYEINDVETPEG--EQPP--PLSTPVGSSTS
QPIPPQ---SHPSTSSSSSDGL-RDNVPCL---KVK------NSPLKQSPGYQTELVIQL
VWVGGEPPQQITSLALNSSYGLVVFGNSNGIAMVDYLQKAVLL---NLSTIELYGSNDPY
R-----------------------------------------------------------
------REPRSPRKSRQPSG---------------------------AGLCDITEGTVVP
--EDRCKSPTSGSSSPHNSDDEQKVNNFIEKVKTQSRKFS-------KMVASDLAKMS--
-------RKLSLPTDLKPDLDVKDNSFSR-SRSSSVTSIDKESR----EAISALHFCETF
TRKAD-SSPSPCLWVGTTVGTAFVITLNLPL----------------GPEQRL---LQ--
PVIVSPS---------------------------GTILRLKGAILRMAFLDA-AGCLMPP
AYEPWT--EHNVPEEKDEKEKLKKRR--------PVSV----------------------
-----------------------------------------------------------S
PSSS-QEISENQYAVICSEKQAKVISLPT---QNCAYKQNITETSFVLRGDIVA------
------------------------------------------------------------
LSNSVCLACFCANGHIMTF---------------------------SLPSLRPLLDVYYL
PLTNM-----------------------------RIARTFC----FANSGQALYLVSPTE
IQRLTYSQETCEN----LQEML------------------GELFTPVET------PEAP-
NRGFFKG---LFGGGAQS----LDREELFGE------SSSGKASRSLAQHIP--------
-GPGGIEGVKGAASGVVGELAR--ARLA--LDERGQK--------------------LSD
LEERTAAMM-----------------------------------SSADSFSKHAHE----
-----------------------MMLKYKD------------------------------
----------KKWYQF
>gi|157017339|gb|EAA09211.5|	Anopheles gambiae
------------------------------------------------------------
---------------------------------------------------MLKFIR--G
------------------------------------------------------------
---------KGQ-------QP---------------------ST-ERQKLQKELFA----
----------FRRTAQHGFPHKPSALAYDLKSKLMAIGTN-----SGVIKVFGRPGVEFY
GQHTSPSNNPADLIVQMLEWIPGTGRLLSLTASNQLVLWEPAGT---------------L
LVAIKNLAFDGK-----------LKKISSLCCSYM-KDTVWIGTEGGNVYQFDVRNFS-V
KESVI--YHDVVLEQLPTSYRLNP--GAIESVKQLPNNHNLLLIAYNRGLAVLWDLETAS
VKQ---------SFISP-------------------GHGQSVGLFIAQDATQFTWYHADG
SFATWDLDSP---IPPENQKY---VPYG---------PDPC-------KAIDRL-IRGHR
GR-CELVVFSGG----------MPRSAYGEHQCVSV--------HCKDG---TKVAFDFT
SKVIDFFVTFN-DVRPE-----Q-----------AEVLVVLLEEELVAYDLTDETLPQIN
A----PYLHSLH-ASAVTCNHLVSQVSPEVYAKIKYAG--EQQMAE----YSCKVWPISG
GIVPNESVDDEEQPM---ERDVLITGHEDGSVKFWDCS---DVCLTPLLHVKTAPLFNNS
DD--FESNLNASTEQLDDGEPPFRKAGQFDPYSDDPRLAVKKVQLCPQTGTLVIAGTAGN
VVMANFEASPQVAEETQSNGPLKMTTMNLVSDR---------------------------
-------------------DGFVWKGHDQL---KVKRQLLEENSPIIE--GVNFLGVLQV
L-----PPAAITCIAMQSKWSLVAAGTAHGLVLFDYQNQAPVLHKCTLNPNDLTGAGETL
------------------------------------------------------------
------SRRKSFKKTLRESF------------------------------RRLRKGRSTR
------NNPNA-------------------------------------------------
-----------GGAGAGGQHQQSAAETRPVERQIEARPVDDGMG----SMVRCLTFAQTF
ITNQ--NVYIPTLWSGTNSSTVSVFVLNLPPKQPAATAAAGENGADESAQTATA-TPRGP
PVTGKLGK--------------------------EIQMKHRAPIIGIAVVDS-NGVPLEF
----QN--VPGPA---------------------P-------------------------
------------------------------------------------------------
-----------HRVLIASEEQFKIFSLPQLK-PVNKYKLTAHEGARVRRIAFATFMCTVP
T---SSLVNSSPPKALVKPASPAAPAQQAADPPTTAADNNTSTTAVNDNNT-SIVGSDVT
THYEISLLCLTNLGDCLVL---------------------------TVPELRRQLNSAAV
RREDI-----------------------------NGISSLC----FTSHGEALYMMSSSE
VQRISLSATK-------IVAPN------------------GMIDVEDWSAPIDGASTEED
NEQQDQQAQETMQAEAASQQEPDD--NASGS------VAAAKSEQSVSREKVSGSATLLT
NGASNPRLSNGVASGDEASPNK---ANETITSSIGDITIDSVRDHLNSTTTTLCSTTTEE
IVGRLSVLS-----------------------------------THTTQSSSTAKNSEIL
SMNSSNIGSLKGIGETTEKTSNSAIIKSIITTVKHGSNATNGEAKESNKTSTITTTTTS-
----------TSVNGN
>gi|114670461|ref|XP_523719.2|	Pan troglodytes
MYWVNPSRPRPVVSGTAPSPSPLLCPLKEIRFLWPAVADPPADTDLVGAPPPPPEERRLA
ATPRSLHHPSPAGSWRDGSPGVWEAARDRGRSGNYFRLREAAGHWARRAVLRPARLR--P
RLAAPEVSRKETAAQQPVGRRGGASGAGG-------------------------------
-------GRRGTPRPRAGAGPGFQVSSGGCRLSKMRRFLRPGHDPVRERLKRDLFQ----
----------FNKTVEHGFPHQPSALGYSPSLRILAIGTR-----SGAIKLYGAPGVEFM
GLHR------ENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGAS-----------E
LQEDESFTLRGPPG-----AAPSATQITVVLPHSS-CELLYLGTESGNVFVVQLPAFRAL
EDRTI--SSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSR
VLY---------HFLSS-------------------QQLENIWWQ--RDGRLLVSCHSDG
SYCQWPVSSEAQQPEPLRSL----VPYG---------PFPC-------KAITRILWLTTR
QG-LPFTIFQGG----------MPRASYGDRHCISV---------IHDG---QQTAFDFT
SRVIDFTVLTE-ADPAA--AFDD-----------PYALVVLAEEELVVIDLQTAGWPPVQ
L----PYLASLH-CSAITCSHHVSNIPLKLWERIIAAG--SRQNAH----FSTMEWPIDG
GTSLTPAPP---------QRDLLLTGHEDGTVRFWDAS---GVCLRLLYKLSTVRVFLTD
TD-----PNENLSAQGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQ
VLVLEL-NDEAAEQ------AVEQVEADLLQDQ---------------------------
-------------------EGYRWKGHERL---AAR------SGPVRFEPGFQPFVLVQC
Q-----PPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPL
------------------------------------------------------------
------SRVKSLKKSLRQSF------------------------------RRMRRSRVSS
RKRHPAGPPGE-------------------------------------------------
-----VRPEAQEGSAKAERPGLQNMELAPVQRKIEARSAEDSFT----GFVRTLYFADTY
LRDS--SRHCPSLWAGTNGGTIYAFSLRVPP-----------------AERRM---DE--
PVRAEQAK--------------------------EIQLMHRAPVVGILVLDG-HSVPLPE
PLEVAH--DLSKS---------------------PDMQ----------------------
-----------------------------------------------------------G
S----------HQLLVVSEEQFKVFTLPKVS-AKLKLKLTALEGSRVRRVSVAHFGSRRA
E-----------------------------------------------------------
DYGEHHLAVLTNLGDIQVV---------------------------SLPLLKPQVRYSCI
RREDV-----------------------------SGIASCV----FTKYGQGFYLISPSE
FERFSLSTKW-------LVEPR------------------CLVDS----------AETKN
HR-----------------------------------PGNGAGPKKAPSRAR--------
-NSGTQSDGEEKQPGLVMERAL--LSDERVLKEI-----------------------QST
LEGDRGSGS-----------------------------------WRSHRAAVGC------
-----------------------SLSNGGE------------------------------
----------------
>gi|50308471|ref|XP_454237.1|	Kluyveromyces lactis
------------------------------------------------------------
-------------------------------------------------MFKSKKLK--T
VSNAIKSVA---------------------------------------------------
------------------------------------------SKDASNGISSKMFE----
----------LSEVSRYGMNGKVCTFAFDPVQSLLAIATD-----SGEIHVYGKQQVEVV
FTLE-------VKAIKEMRFIKGI-YLIVVDAKDSLSVLSLH-----------------K
KALLASFFPPGK--------------ITCIETDPS-LNWVLIGLQSGATIVYDVDRDY-L
SPFKI--ENLQKSRF----FKREP-LSPVVSLQWNPRDIGTVLIAYDK-VTVLYSFVEND
VKQ---------QFIHEEGENV--------------PKVLHSVFH--PNGLNIMTVHDGN
CLVFWDSNTG---QKIVSRFLLDEDPLI--------TSTVS-------TSIFKVAWIQEK
DENSTSLLFAGGSGDATTGDHSLTLINLGPTPIYTVTSYDKMATYYAQPVSQKIIPVPND
ASIINFLPLANGNPYYA--GNFA-----------PMVILVLLDDGEIETLLYPSGSITYK
AS---LFPQSISWIRPAATTSYATSVPKKTWLGMMSAT------------YN-RDYILKG
GYPAKKTLRVHD------SRSALSTGHTNGSVRIWDASHG-ELDESSVFDVNVSHSLNTS
QS-----------------------------------VAVDHISYAAETAELAVSIESGD
VVLYKFQVNQFFTS------QKDVA-LEMNFRR---------------------------
-------------------FSLNDKPHEILV--DIR-----DRAPNNIREGFMPVTAVHA
------RKGRVSSLC-NSNVGFVAIAYEDG----------------TIIVIDRRGPAMIY
M-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------DSISKISKVRS----------SYVSQFEFTIME
YGED--GYSSILLLCGTDAGEVILLKIIPDP-------------------------SG--
RFTVQPYD--------------------------ALKATDDGPIVSLATFSKESGSSCRA
SIPRMQ--QLSKG---------------------LRVQ----------------------
-----------------------------------------------------------A
Q------------IVISGRTDIRLITPGKSKDTHRIFKYPIA----VSGLSIVPFLNAKN
E-----------------------------------------------------------
HSIATVLVTVLINGEIKVL---------------------------SLPELKEIKSFAPL
ANVHS-----------------------------KYVKESG----VLVNGDIVYRVSKTE
AFLLTVIKKSSTTSQSQNSEET------------------DSLYNPNLR------IKCRP
YYNSLQ----WVRGSIYCK--PEDLDHLLGEGRPEQKYEEEKIAKGTISLSP--------
-EEKTHNTHELSANGRYQYQAP--VRHS--AKSGGYGPLRSISRAMQNG--------MDS
IEDTFNDYA-----------------------------------TAANETMNDATDQIGK
-----------------------DLIKGAF------------------------------
----------NSKIGL
>gi|81909525|sp|Q5DQR4|STB5L_MO	Mus musculus
------------------------------------------------------------
--------------------------------------------------MKKFNFR--K
VLDGLTASSPGSGSSSGSNSGGAGSGSV--------------------------------
-------HPGGTAG-----LP---------------------REEIQESLTSDYFQ----
----------ICKTVRHGFPYQPTALAFDPVQKILAIGTR-----TGAIRILGRPGVDCY
CQHE------SGAAVLQLQFLINEGALVSASSDDTLHLWNLRQK---------------R
PAILHSLKFNRE-------------RITYCHLPFQ-SKWLYVGTERGNTHIVNIESFI-L
SGYVI--MWNKAIEL---STKTHP--GPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKR
AEL---------RVYYD-------------------EAIHSIDWH--HEGKQFMCSHSDG
SLTLWNLKSP---SRPFQTT----VPHGKSQREGR-KSESC-------KPILKVEYKTCR
NS-EPFIIFSGG----------LSYDKACRRPSLTI---------MHGK---AITVLEMD
HPIVEFLTLCE-TPYPN--EFQE-----------PYAVAVLLEKDLIVVDLTQTNFPIFE
N----PYPMDIH-ESPVTCTAYFADCPPDLILVLYSIG--VKHKKQ---GYSNKEWPVSG
GAWNLGAQT---------YPEIIITGHADGTIKFWDAS---AMTLQMLYKLKTSKVFEKQ
KA-----GEGKQTCELVEEDP----------------FAVQMIYWCPESRIFCVSGVSAY
VIIYKFSRHEVTTE------IVS-LEVRLQCDVEDIITPEP--ETSP--PFPD---LSSQ
LPPSRS---LSGSTNTVSSEGVTKDSIPCL---SVK------TRPVRMPPGYQADLVIQL
VWVDGEPPQQITSLSISSAYGIVAFGNCTGLVVVDFIQKTVLL---SMGTIDLYRSSDLY
Q-----------------------------------------------------------
------RQPRSPRKNRQFIAD----NFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPL
E-LERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSAAC--
-------MEISLPVTTE---ETRENSYNR-SRSSSISSIDKDSK----EAITALYFMESF
ARKND-STVSPCLFVGTSLGMVVLISLNLPS----------------SDEQRF---TE--
PVVVLPS---------------------------GTFLSLKGAVLTFSCMDR-TGSLMQP
PYEVWR--DPNNTD---ENEKTWKRK--------LVMN----------------------
-----------------------------------------------------------Y
SSSS-QEMGDHQYTIICSEKQAKVFSLPS---QTCLYVHNITETSFILQADVVV------
------------------------------------------------------------
MCNSACLACFCANGHIMIM---------------------------SLPSLRPMLDVNYL
PLTDM-----------------------------RIARTFC----FTNEGQALYLVSPTE
IQRLTYSQEMCDN----IQDML------------------GDLFTPIET------PEAQ-
NRGFLKG---LFGGSGQT----FDREELFGE------ASAGKASRSLAQHIP--------
-GPGSIEGMKGAAGGVMGELTR--ARIA--LDERGQR--------------------LGE
LEEKTAGMM-----------------------------------TSAEAFSKHAHE----
-----------------------LMLKYKD------------------------------
----------KKWYQF
>gi|83767670|dbj|BAE57809.1|	Aspergillus oryzae
------------------------------------------------------------
---------------------------------------------------MAHFLR--G
------------------------------------------------------------
-------KQAGI------------------------------QKDLSDGLSPDLFA----
----------LDDFARYGINSQISAIAYDPVQSLIAVGTSDTQFGSGQIYVFGQRRVSVV
FSLP------RKASAKFLQFCAD--KLVSVDSKSEICVFSLETR----------------
-QTLFSYAPPNH--------------VSALLTDPS-LDYAFIGLQNGDIIAYDLDRET-L
TPFKVPNLWAQR------NPRARF--CPVIALSFSPRDIGKILVGYPEG-AVTFSFKQNL
AQK---------YFEYEVPPGALGGNCDVPSQEPRRPRLTKAVWH--PNGIFVLTVHDDN
SLVLWDSKDG---RKIAARSIT--TPNIDQPGASRERPLSAGSAVGLRDPITHIAWCVKG
NGDDSGLLIAGGK-PKAEANKGLTFIDLGPTPNYQTSSWAMISNYFESPKQITDLSTPPG
AEVVDFCLIPRASPYYA--GGHD-----------PIALIAVLSSGELITLSFPSGHPITP
TNMIHPSLSFVH---PFVNKMTLTPVDRSAWLGL------RERRSQ-------GPKFLLG
GAEGKKVLKRFE------DRNVITTAHADGTIRLWDVGHD-EIENGDVIQVDLARAVGRV
SN-----------------------------------VEVTEMALSGSTGELSVGLRSGE
VVIFRWGSNGSFGH------EEPAGANEGP------------------------------
------------------------GKLTKV---AHR------TDPGLKQ-GLLPLTLLDM
------QQGSVTALK-HSQVGFVAAGFEGG----------------SLVIIDLRGPAVIH
T-----------------------------------------------------------
------ARLSELTKPSKR------------------------------------------
------------------------------------------------------------
------------------------SSF------LRHRSSDDAPP----EWPTSIEFGVLT
LEGE--DYSSICCFVGTNRGNFATFKILPTD-------------------------NG--
GYTASFAG--------------------------ATLLDDK--VISIIPINAETGDLALA
TPNAVG--GLRNG---------------------VQVH----------------------
-----------------------------------------------------------G
V------------VVAVTVSGCRIFKPATSKGAHKSWEDYLCDSAAVVKV----------
------------------------------------------------------------
EGRGYSLVGLFGDGNVRAF---------------------------SIPGLKEMGCKEIN
YMADM-----------------------------KRLSEST----ICSNGTVLTWTGPSE
VGLFNVWGAGTG-----LRHSE------------------DQLYNIQAAI-----PPRPT
ITNMQ-----WISGTQYIS--PADMDILIGGPDRPPSKKMQEQMKLEDQERRRLAREGR-
-TMSNLSQEQGSQEGYWSYMQRQVQQRTENLNLAGDQ--------------------MER
LEENSSNWA-----------------------------------RDVNKYVQNQKKK---
-----------------------AVLGGSK------------------------------
-------------FGL
>gi|73956207|ref|XP_546657.2|	Canis familiaris
------------------------------------------------------------
-----------------------MDPEGCPPTQEAWLADYNPGRTRAAAHARREHLREPG
RARGPSLPPLSGRQGRGERHRGTPIGRVVRQSRSATRGAARRILRAAAAAAAGAAPAAGR
KMMKFRFRRQGA-------DP------------------------QREKLKQELFA----
----------FNKTVEHGFPNQPSALAFDSELRIMAIGTR-----SGAVKIYGAPGVEFT
GLHR------DTATVTQMHFLPGQGRLLTLLDDSSLHLWEIVHHHGCA-----------H
LEEALSFQPPSRPGFDSASGPLSLARVTVVLLVAA-GDMAALGTEGGSVFFLDVPTLTLL
EGQTL--APDEVLRSVPDDYRCGKALGPVESLQGHLQDPTRILIGYSRGLLVIWNQAAQC
ADR---------VFLGN-------------------QQLESLCWE--RSGRTLVSSHSDG
SYAVWSVDAG---DSPMTQPTVTTTPYG---------PFPC-------KAINKILWRNCE
SG-DHFIIFSGG----------MPRASYGDRHCVSV---------LRAE---TLVTLDFT
SRIIDFFTVHS-TRPED--EFDE-----------PQALAVLLEEELVVLDLQTPGWPAVP
A----PYLAPLH-SSAITCSAHVANVPAKLWARIVSAG--EQQSPQP--ASSTLSWPITG
GRNLAQEPS---------QRGLLLTGHEDGTVRFWDAS---GVALRPLYKLSTAGLFQTD
CE-----HADSLAQATEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQ
VLVLEL-SDVPSEQ------AVSVASVDLLQDR---------------------------
-------------------EGFTWKGHERL---SPR------TGPLPWPAGFQPRVLVQC
L-----PPAAVTAVTLHAEWSLVAFGTSHGFGLFDYQRRSPVLARCTLHPNDSLAMEGPL
------------------------------------------------------------
------SRVKSLKKSLRQSF------------------------------RRIRKSRVSG
--KKRATSATS-------------------------------------------------
-------KLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLS----GVVRCLYFADTF
LRDA--AHHGPTMWAGTNSGSVFAYALEVPA-------------AAAGSEKRA---ER--
AVEAVLGK--------------------------EVQLMHRAPVVAIAVLDG-RGRPLPE
PYEASR--DLAQA---------------------PDMQ----------------------
-----------------------------------------------------------G
G----------HAVLIASEEQFKVFTLPKVS-AKTKFKLTAHEGCRVRKVALATFASVAC
E-----------------------------------------------------------
DYAETCLACLTNLGDVHVF---------------------------SVPGLRPQVHYACI
RKEDI-----------------------------SGIASCV----FTRHGQGFYLISPSE
FERFSLSARN-------ITEPL------------------CSLDISW--------PQDTT
RASY------RLRESPK-------LSQANGTPGIVLAPQSRNGSPDPGHSRR--------
--ADTPEPPEAMLSPMSVDSAT--SADTT-LDTTGDVTVEDVKDF------------LGS
SEESEKNLR-----------------------------------NLAEDEARACS-----
-----------------------ILIK---------------------------------
----------------
>gi|153791336|ref|NP_001093451.	Danio rerio
------------------------------------------------------------
--------------------------------------------------MKKFNIR--K
VLDGLTAVSSPSPS----------------------------------------------
-------PQLGA-------KE---------------------NELIPETLQSEHFQ----
----------LCKTVRHGFPYQPSSMAFDPVQKILAIGTQ-----SGALRLFGRPGVECY
CQHE------SGAAVIQLQFLINEGALVSALADDSIHLWNLRQK---------------R
PAVLHSLKFNKE-------------RITFCHLPFQ-SKWLYIGSERGNIHIVNVESFT-L
SGYTI--MWNKAIEL---SSKAHP--GPVVHISDNPMDEGKLIIGFESGIVVLWDLKSKR
ADY---------RYTYD-------------------EAIHSVAWH--HEGKQFICSHSDG
TLTIWNLKSP---AKPIQTI----TPHGKQPKDGK-KPEPC-------KPILKVEYKTTR
AG-DPFMIFSGG----------LSYDTVGRRPCLTV---------MHGK---STAVLEMD
YPIVDFLTLCE-TPYPN--DFQE-----------PYAVVVLLEKDLVVIDLAQNGYPIFE
N----PYPMMIH-ESPVTCCEYLADCPVDLIPALYSVG--SRQKRQ---GYSKKEWPVSG
GNWGLGTQS---------YPEIIITGHADGSVKFWDAS---AIMLQVLYKLKTAKVFEKA
RC-----KEEKPSTEIVDEDP----------------FAIQLMSWCPESRMLCVAGVSAH
VIIYRFSKQEITTE------VVQLLELRLQHELNDLESPEGGGDQTP--APPTPSTSPSP
QTAGPQ---THTSSSSNSSDGM-RDNVPCL---KVR------SSPLKQSPGYQVELVVQL
VWVSGEPPQQISSLAINSCYGLVVFGNSNGLAVVDYLQKTVLL---NLGTVELYGSNDPY
Q-----------------------------------------------------------
------RQPRSPRKSRQPSG----------------------------GLCDINEGSATS
--EDRCKSPTS--------------------VLMSNHQHF-------YNGGGRGAKMS--
-------RKLSLPTELKPDLDNRDNSFSR-SRSSSVTSIDKETR----EAITSFYFCETY
TRKAD-GGLTPSLWVGTSLGTVLAISLNMPP----------------AGEQRL---LQ--
PVIVSPC---------------------------GTLFRLKGSVVRMAFLDS-TGSILPS
PFEPWY--EPNAPANGEERDKVRKRR--------PVSV----------------------
-----------------------------------------------------------S
PSTS-QELNENQYAVVCSEKQAKVVILPS---QTCVFKHNITETSFVLRADVVQ------
------------------------------------------------------------
MNAGICVACFCANGHIMTL---------------------------SLPGLRPLLDVNYL
PLTDM-----------------------------RIARTFC----FTNLGQALYLTSPTE
IQRITYSQEVCEN----LQEML------------------GELFTPVET------PEAP-
NRGFFKG---LFGGGAQS----LDRMELFGE------TGAGKAPRSLAQHIP--------
-GPGGIEGMKGAASGIVGDLAR--ARIA--LDERGQK--------------------LSE
VEERTAAMM-----------------------------------ASADSFSKHAHE----
-----------------------MMLKCKD------------------------------
----------KKWYQF
>gi|91077482|ref|XP_968585.1|	Tribolium castaneum
----------------------------MWCLGANLALICKIAIARCTGECRITWGRSHA
YPAGVPGTRRIAKGPYLAERRRDLDWTLTRTLHPLHGAMKRDKDPDRRDVMKKFTFK--G
VLENFRTS--------------------V-------------------------------
--------AQQV-------KP---------------------DQEIQETLRPENFQ----
----------VKRTFRHGFPFQPTAMAYDPVQRLLAIGSK-----CGSLRILGQPGVDIH
VRHDI-DGSPGSSAVLHLQFLVNEGALVSATADDSLHLWNFRQK---------------V
PQIVQSLKFQKE-------------KITCMHLPLQ-SKWLYVGTERGNVHVVHIETFA-L
SGYVI--NWNKAIEV---SRKTHP--GALVHLSDNPLDASKLLIGYESGQVVLWDLRNKS
AEM---------RWQTA-------------------E-LKSVAWH--HEGKQFMCSHADG
TLTTWSIKDR---TKYLCIS----QPHAKLNKDG--KAEQC-------KPINKVEWKSSR
TG-EAYVIFSGG----------MPYDQAGRTPSITV---------VHNK---TTTVLEME
SNVIDFITLCE-SFYSS--ELQE-----------PYAIIALLQNDLVVMDLQTAGFPCLE
N----PYPMDIH-ESPVTCCSYLADCPADLIPAFYYVGRASGNKRQ---GFSEMDWPVSG
GSWSAQSCS---------YSEIILTGHADGSIKFWDAS---AGTLQVLYKLKTAKIFEKQ
RA----------RSLDKEEDP----------------FAIEIISLCPESRKLCVAGASSH
VILFTYKKSESNDE------VTV-LEIPIVYEV-----PEE-GEISPDCQFSGPGSAGSD
MLDFDNKKVLKGFEAIRWVDDSELQDTPTL---KVR------AGIQKKLPGFQAQLVCLT
PWNNGEPPSHITALTINSSYGLMAYGNEAGIVIIDIEQKVCLL---NVGSPDLYGAQDPY
S-----------------------------------------------------------
------RVPRSPKRGGTASD----------------------------------ILPVNM
D-DRQPRSPSI-------------------------------------------------
-----------------DQVNKLDSSFSR-SRSSSMSSLENITS----EAIQCLIFADSF
AKKTEPTSLIPTLWVGTSLGSVLTILITPPD-----------------PDSRS---SQ--
PVVVSLVG--------------------------VTIFRLKGAILSMSFLDC-NGSLIPN
AYESWR--DDNRDKREKTPTKCQNRMS-------PTLS----------------------
-----------------------------------------------------------D
QQNRGDSFSDRQYVVIVSEKQARVVALPS---QTCVYRQQLTDADFVVKAEVIS------
------------------------------------------------------------
LKDSVCLLGYISNGHLVAY---------------------------SLPSLRPLIDIDFL
PLSELSFQTQSNKGIVDPMLSIWGQQLIVNEDTDQIARTFC----FSNRGHGLYLASPSE
IQKFTLCTEFCSN----LSEMM------------------GELFLPLDM------PEPP-
KEGFFKG---LFGGGIRS----LDREELFGE-------SSGKANKSIAKHIP--------
-G--SLQEMGTRVTSATGEVNR--AHKL--MIERGEK--------------------LSQ
LEDRAEKMR-----------------------------------SEAENFQASAHD----
-----------------------LMLKYKD------------------------------
----------KKWYQL
>gi|119599923|gb|EAW79517.1|	Homo sapiens
------------------------------------------------------------
---------MEMFAFANVNNCQPHLMIRTIKPLLVTAGVNHRYKLSAVFKMKKFNFR--K
VLDGLTASSPGSGSSSGSNSGGGAGSGSV-------------------------------
-------HPAGTAG-----VL---------------------REEIQETLTSEYFQ----
----------ICKTVRHGFPHQPTALAFDPVQKILAIGTR-----TGAIRILGRPGVDCY
CQHE------SGAAVLQLQFLINEGALVSASSDDTLHLWNLRQK---------------R
PAILHSLKFNRE-------------RITYCHLPFQ-SKWLYVGTERGNTHIVNIESFI-L
SGYVI--MWNKAIEL---STKTHP--GPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKR
AEL---------RVYYD-------------------EAIHSIDWH--HEGKQFMCSHSDG
SLTLWNLKSP---SRPFQTT----IPHGKSQREGR-KSESC-------KPILKVEYKTCK
NS-EPFIIFSGG----------LSYDKACRRPSLTI---------MHGK---AITVLEMD
HPIVEFLTLCE-TPYPN--EFQE-----------PYAVVVLLEKDLIVVDLTQSNFPIFE
N----PYPMDIH-ESPVTCTAYFADCPPDLILVLYSIG--VKHKKQ---GYSNKEWPISG
GAWNLGAQT---------YPEIIITGHADGSIKFWDAS---AITLQMLYKLKTSKVFEKQ
KV-----GEGKQTCEIVEEDP----------------FAIQMIYWCPESRIFCVSGVSAY
VIIYKFSRHEITTE------IVS-LEVRLQYDVEDIITPEP--ETSP--PFPD---LSAQ
LPSSRS---LSGSTNTVASEGVTKDSIPCL---NVK------TRPVRMPPGYQAELVIQL
VWVDGEPPQQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVLL---SMGTIDLYRSSDLY
Q-----------------------------------------------------------
------RQPRSPRKNKQFIAD----NFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPL
E-LERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSAAC--
-------MEISLPVTTE---ENRENSYNR-SRSSSISSIDKDSK----EAITALYFMDSF
ARKND-STISPCLFVGTSLGMVLIISLNLPL----------------ADEQRF---TE--
PVMVLPS---------------------------GTFLSLKGAVLTFSCMDR-MGGLMQP
PYEVWR--DPNNID---ENEKSWRRK--------VVMN----------------------
-----------------------------------------------------------S
SSAS-QEIGDHQYTIICSEKQAKVFSLPS---QTCLYVHNITETSFILQANVVV------
------------------------------------------------------------
MCSSACLACFCANGHIMIM---------------------------SLPSLRPMLDVNYL
PLTDM-----------------------------RIARTFC----FTNEGQALYLVSPTE
IQRLTYSQEMCDN----LQDML------------------GDLFTPIET------PEAQ-
NRGFLKG---LFGGSGQT----FDREELFGE------ASAGKASRSLAQHIP--------
-GPGSIEGMKGAAGGVMGELTR--ARIA--LDERGQR--------------------LGE
LEEKTAGMM-----------------------------------TSAEAFSKHAHE----
-----------------------LMLKYKD------------------------------
----------KKWYQF
>gi|156549634|ref|XP_001604186.	Nasonia vitripennis
------------------------------------------------------------
---------------------------------------------------MLKFIR--G
------------------------------------------------------------
---------KGQ-------QP---------------------TA-ERQKLQKDLFA----
----------FRKTVQHGFPNKPTAIAWDPSLRLMIIGTA-----SGAIKVFGRPGVEFY
GQHAS---ESGEIAVTKIIALPNEGRVVSLCDDNSLHLWEINEN---------------S
VIETKSLALEGK-----------LKKISAMCLESN-GDHLLLGTEGGNIYLLNLKTFT-M
SDTII--YQDVVMQNVPKDFKVNP--GPVEAIAEQPGHPDNILIGYNRGLMVLWNKATPG
AQQ---------TFVST-------------------QQLESVHWV---SESRFVFSHNDG
SYAFASPGNE---EPPTPT-----TPYG---------PFPC-------KAITKIVVHPTE
DD-DELILFSGG----------MQRSVHSDRHTITV---------KQEGKNKKHVVFDFT
SKVIDFFTILPKKKQPQ--DGDEEKDEKAKNTESPEALIVLAEEELIAIDLTDPDWKMMA
L----PYLVSLH-ASAVTCSQHVPNIPEELWEAIESAG--KAQTGH---LYSEKEWPIDG
GVLLCRKPAESDKPK---PRELLLTGHEDGTVRFWNAS---DVALTPLYKYNSSILFTGE
HL----DVLEQPPEDEEDEWPPFRKVGTFDPYSDDPRLAVKKVLLCPLSSTLVIAGTAGH
VITAKISAEAINKE-------IKSVTMNVVNDR---------------------------
-------------------DGFVWKGHEHL---PAR------TASISFAVGFQPHCLLQL
Y-----PPAAVTALAMHSEWGLLAAGTAHGLAVFDYVRIKAISVKCTLNPNDLSGAGDTP
I-----------------------------------------------------------
------SRRKSFKKSLRESF------------------------------RRLRKGRSQR
RATTATGSPPRPATAPEA------------------------------------------
-------KKKDAPSIASSPSGDAPIDVKPVERQVEARPVDDASG----SMVRCLYFARSY
IISM--QNTTPTLWAGTNNGTVYVFTLAIPA-----------------GVRRT---EE--
DVNCTLGK--------------------------EIQLKHRAPVIAITILDG-SNIPLPE
PFEAER--GVCPG---------------------PDMA----------------------
-----------------------------------------------------------S
P----------HRVVIASEEQFKIFNLPSLK-PFCKYKLTAHEGSRVRKTGFAKFTCPVE
P----------------------------------SG-----------------------
QHEETCLLCLTNLGECLVL---------------------------GIPELRRQLNAATI
KREDI-----------------------------NGISSLT----FTKAGEALYLHSSSE
LQRISLSAAK-------MTKAH------------------CALNLPPNARST---PEVA-
----------TPEQKDTSTTEPEEKNEEATNEEVVVEEKGVNQTQALPKVITENGVVGST
NGEESPKEPSLRPAASTTDVNG--DDDRQDLSSLGDITIDSVKDHLLNATS------SED
LHNRLAGLKMEVTSRTSEISTQNQSVVVKTTTVISQQASTNGITTNGDVETQTTQQNACE
QVNSTTVEREISSGTETTTTHATITLPPNVEISAADLANLECTTTTVITEKTKAPLAK--
----------PEEVGS
>gi|121705688|ref|XP_001271107.	Aspergillus clavatus
------------------------------------------------------------
---------------------------------------------------MAHFLR--G
------------------------------------------------------------
-------KQSGI------------------------------QKDFSDGLSPDFFV----
----------LDDYARCGVNSQISAFAYDPVQSLLAAGTSDTQFGSGQVYVFGQRRVSAV
FALP------RKASAKLIQFCAD--KLIVVDSKSDVTIYSLEAQ----------------
-KILVSYAPPSH--------------ATALLTDPS-LDYAFIGLQNGDIIAYDLDRET-L
TPFRVPNLWAQR------NPRARL--CPVLSLAFSPRDIGKILVGYPEG-AVTFTFKQNI
AQK---------YFEYEVPAGAVGGNSEVPSQDTRRPKLTRALWH--PNGIFVLTVHDDN
SLVFWDSKDG---RKILARTME--ATHIDEPGASPNRRLST-ADVIFREPIKQIAWCVKA
NGEDSGLLIAGGR-PKAEANKGLTFIDFGGTPNYQTSTWPMITSYFENPRQILNIPTPPG
VDVVDFCLIPRASPFYA--GAHD-----------PIALLTLSSYGELITLSFPSGHAITP
SNMIHPYLSFVH---PFVTKMNMTPIDRSAWLGL------RERRSQ-------GPKFAIG
GAEGKRSLKRFE------DRNIISTAHADGTIRLWDVGHDDEIENADVIQVNLSRAVGRV
SD-----------------------------------VEVAEMSVSGSTGELSVGLKTGE
VVVFRWGSNSNFGH------EEPPGVNEGA------------------------------
------------------------GKLTRI---SHR------ADPGLKQ-GMLPLTLLNM
------QQGAVTALK-HSHVGFVAAGFQNG----------------SLTILDLRGPAVIH
A-----------------------------------------------------------
------ANVSDFVKTSKR------------------------------------------
------------------------------------------------------------
------------------------GSF------LKHRATESAGP----EWPTSIEFGVLT
LDDE--DYSSICCFVGTNRGNLATFKILPGN-------------------------DG--
AYMAQFAG--------------------------VTQLDDR--VLNIIPIDADNGSPAVA
NPNLVG--SLRSG---------------------GKVN----------------------
-----------------------------------------------------------G
V------------VIAVTVSGCRIFKPATSKGAHKSWDDYLCDAAAVVKT----------
------------------------------------------------------------
EARGYSLVGLFGDGKARAF---------------------------SIPGLKEIGCTSID
QIVEM-----------------------------RRLSEST----VCANGSILAWTGPSE
VAAFNVWGSGAG-----LRPSD------------------NQLFNPQATI-----PARPT
ITNMQ-----WISGTQYIS--PADMDILIGGPDRPPSKRMQEQMRLDDQERRKLAREGR-
-TNSNMSQSSASQEGYWSYMSRQVQERTERLGLASDS--------------------MDR
LEENSSNWA-----------------------------------RDVNKYVQNQKK----
-----------------------KAILGAL------------------------------
----------GSKFGL
>gi|70999596|ref|XP_754515.1|	Aspergillus fumigatus
------------------------------------------------------------
---------------------------------------------------MAHFLR--G
------------------------------------------------------------
-------KQTGI------------------------------QKDFSDGLSPDLFN----
----------VDDYARCGVNSQISVLAYDPVQSLLAVGTSDTQFGSGQIYVFGQRRVSAV
FSLP------RKASAKFLQFCAD--KLISVDSKSEITIFSLETQ----------------
-KALVSYAPPSH--------------ATALLTDPS-LDYAFIGLQNGDIIAYDLDRES-L
TPFRVPNLWAER------NPRARL--CPVLSLAFSPRDIGKILVGYPEG-AVTFTFKQNV
AQK---------YFQYEIPPGAVGGNSEIPSQDTRRPKLTRALWH--PNGIFVLTVHDDN
SLVFWDSKDG---RKILARTME--NTHIDEPGASPNRRFST-AEAIFRDPITQVAWCVKA
NGEDSGLLIAGGR-PKAESNKGLTFIDFGATPNYQTSTWPMITNYFENPKQVQNIPAPPG
AEVIDFCLIPRSSPFYA--GAHD-----------PIAMITLLSSGELITLSFPSGHSITP
TNMIHPFLSFVH-PFVTKCT--MTPIDRSAWLGL------RERRSQ-------GPKFVIG
GAEGKRALKRFE------NRNIITTAHADGTIRLWDVGHDDEIENADVIQVDLARAVGRV
AN-----------------------------------VEVTEMSVSGSTGELSVGLKSGE
VVVFRWGSNGNFGH------EEPPGTNAGA------------------------------
------------------------GKLTRI---THR------ADPGLKQ-GMLPLTLLNM
------QQGPVTAVK-HSHVGFVAAGFQNG----------------SFVIMDLRGPAVIH
T-----------------------------------------------------------
------AQVSDFAKTSKR------------------------------------------
------------------------------------------------------------
------------------------GSF------LKHRATESTAP----EWPTSIEFGVLT
LEGE--DYSSICCFVGTNRGNLATFKILPGD-------------------------DG--
AYMGQFAG--------------------------VTQLDDK--VLNIIPIDADQGTPALA
TASIVA--GLRTG---------------------AKVN----------------------
-----------------------------------------------------------G
V------------VIAVTVSGCRIFKPATSKGAHKSWDDYLCDAAAVVKT----------
------------------------------------------------------------
EGRGYSLVGLFGDGNARAF---------------------------SIPGLKEIGCTSIH
QIADM-----------------------------RRLSDST----VCPDGSVLTWTGPSE
VAVFSVWGSGTGLYGPLSLDPVFVQRKERPANKHDRRSSDCRLFNPQAAI-----PARPT
ITNLQ-----WISGTQYVS--PADMDLLIGGPDRPPSKRMQEQMRLEDQERRRLAREGR-
TGSNLSQASTGSQEGYWSYMTRQVQERTERLGIAGES--------------------LDR
LEENSSNWA-----------------------------------RDVNKYVQNQKKK---
-----------------------AILGG--------------------------------
----------KFW---
