>gi|118789109|ref|XP_317218.2|	Anopheles gambiae
------------------------------------------------------------
----------------MFYLLSLFLSLFRFNPAFNMATIRQAINETIERVRIPTPTRLRD
LIRQIRA-------------------------------ARTAAEERAVVNRECAYIRSTF
REE---DSVWRCRNIAKLLYIHMLGYPAHFGQLECLKLTASP--RFTDKRIGYLGAMLLL
DERQDVHLLITNCLKN-----------DLNSPTQFVVGLALCTLGAIASPEMARDLAGEV
EKLMRS--PNAYIRKKAALCAFRIIKRVPELMEI--F-LPATRSLLNEKN---------H
G---------------------------------------------------------IL
IAGVTLITEMC-------------EKSSD-----------TLNHFKKVRLFFGKLTIVPN
LVRILKNLILAGYS--PEHDVSGVSDPFLQVKILRLLRIL--------GH----------
------ND---PDASEAMNDILAQVATNTETS--------KNVGNTILYETVLSIMDIK-
-----------------------------SEGGLRVLAVNILGRFLLNS-----------
---DKNIRYVALNTLLRTVHAD--ISAVQRHRTTILECLK-DPDVSIRRRAMELSFALIN
SQNIRAMSKELLVFLEKA---D--------------------PEFKAQCSSRMVHVAERY
AT----SIR--------WRLDTLLSVLIAAGNYVRDDVVSSTIHLI--LNSPPEEQ----
------AYIGLRLWSSVH-NVA---NSEEKQPLLQVAVWTIGEYGDLLLSSERIEDV---
---EI---PAEHQLVDIYQRLLWSTSVSTT----TKQYALVSLAKLSTRIRTKEEETRVK
QMIEAFG--SHLNIDLQQRGVEFAQLFRDY--SHLRPALLEKMPKIQKTLPN--GTDAEG
GGFDDQQPTIDLIEGGD----------------------------DGDSSLMINTSGGMV
-----GKMGSDS---------------------RALLDLL--------------------
------------GGGDDPIDGLALTPTADVLISGSTTATTNGKSVVGGAPLPPTT-----
-GNNQDLLDLLG-SLDMPASTPPAAVNSSLGA----------------------------
-STPVLGGIGLDLNSLNDNSIKNGTGGPNLLANSSSFGGLDNLLNSNLSPTTMPTTM---
-PAMLPGLGSPLGSGLGS-----LTSPTSPTGLVSTNGTTGSLFSDFSAAVINNNDVRTE
HAKLLTALDKNGILVQLSAK----HTGG---ALQILMTATNNSL-TTLE-----------
--------QYLFQAAVPRSFSLQ-------------MLSP-SGSTLPP--GGTI------
----------------TQEMRV-TSTAK---ATL--------------------------
--------------RMRLRISYQSDGNPVQEQ---------TEVSGFPEEPTE-------
-----------------
>gi|149699309|ref|XP_001500541.	Equus caballus
------------------------------------------------------------
---------------------------------------------------MPAPIRLRE
LIRTIRT-------------------------------ARTQAEEREMIQKECAAIRSSF
REE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQ--KFTDKRIGYLGAMLLL
DERQDVHLLMTNCIKN-----------DLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEV
EKLLKT--SNSYLRKKAALCAVHVIRKVPELMEM--F-LPATKNLLNEKN---------H
G---------------------------------------------------------VL
HTSVVLLTEMC-------------ERSPD-----------MLAHFRKNE------KLVPQ
LVRILKNLIMSGYS--PEHDVSGISDPFLQVRILRLLRIL--------GR----------
------ND---DDSSEAMNDILAQVATNTETS--------KNVGNAILYETVLTIMDIK-
-----------------------------SESGLRVLAINILGRFLLNN-----------
---DKNIRYVALTSLLKTVQTD--HNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVN
GNNIRGMMKELLYFLDSC---E--------------------PEFKADCASGIFLAAEKY
AP----SKR--------WHIDTIMRVLTTAGSYVRDDAVPNLIQLI--TNSV-EMH----
------AYTVQRLYKAIL-GDY---SQQ---PLVQVAAWCIGEYGDLLVSGQCEEEE---
---PI--QVTEDEVLDILESVLISNMSTSV----TRGYALTAIMKLSTRFTCTVNR--IK
KVVSIYG--SSIDVELQQRAVEYNALFKKY--DHMRSALLERMPVMEKVT----------
--TNGPTEIVQTNGETE----------------------------PAPLETKPPPSG---
-----PQPTSQA---------------------NDLLDLL--------------------
------------GGND-------------------------ITPVIPTAPTSKPA-----
-SAGGELLDLLG-DIN--------------------------------------------
---------------------------------------------LTGAPAAAPA-----
-PASVPQISQP-PFLLDG-----LSSQ----------PLFNDIATGIPS-----------
ITAY----SKNGLKIEFTFE-RSNTNPS---VTVITIQASNSTE-LDMT-----------
--------DFVFQAAVPKTFQLQ-------------LLSP-SSSIVPAFNTGTI------
----------------TQVIKV-LNPQK---QQL--------------------------
--------------RMRIKLTYNHKGSAMQDL---------AEVNNFPPQSWQ-------
-----------------
>gi|70991008|ref|XP_750353.1|	Aspergillus fumigatus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MILCRRNNVAKLLYLFTLGERTHFGQIECLKLLASH--RFADKRLGYLGTMLLL
DENQEVLTLVTNSLKN-----------DLNHSNQYIVGLALCALGNIASVEMSRDLFTEV
ESLLST--ANPYIRRKAALCAMRICRKVPDLQEH--F-LEKAKALLSDRN---------H
G---------------------------------------------------------VL
LCGLTLVIDMC-------------EAEEA-----EEGQEGVIEMFR---------PLAPG
LVRALKGLTTSGYA--PEHDVSGITDPFLQVKILRLLKVL--------GR----------
------GD---AATSELINDILAQVATNTDST--------KNVGNAILYEAVLTILDIE-
-----------------------------ADSGLRVLGVNILGKFLSNK-----------
---DNNIRYVALNTLNKVVAIE--PNAVQRHRNTILECLR-DPDISIRRRALDLSFMLIN
ESNVRVLVRELLAFLEVA---D--------------------NEFKPAMTTQIGIAADRY
AP----NKR--------WHVDTILRVLKLAGAYVKEQILSSFVRLI--ATTP-ELQ----
------TYCVQKLYTSLK-EDI---SQE---GLTLAATWVIGEYGDSLLRGGQYEEE---
---ELVKEVKESDIVDLFNNILNSTYATQT----VVEYITTASMKLTVRMTDPAQIERLR
RFLNSRT--ADLSVEIQQRAVEYTNLFGY---DQIRRGVLERMPPPEIREEQRV------
--LGAPSKKRQSKLLKD----------------------------KSKK-----------
-----PAKQAEQ---------------------DLLVDLM--------------------
------------GGAD-----------------------------VPATNPAANG----S
QNTADLLADILGGDSGISSPAPQAAHAPAQSV----------------------------
--------------------------------------NTSAIMDLFGSNGATPS-----
-PRPAEPASAS-VDILGG---------------LGSAPSPAPSPSAAAV-----------
HTAY----NKNDLTLTLQVQ---RAGHG---NAQIQARFRNVSDFSQFS-----------
--------HVGLQAAVPKSQRLQ---------------LS-AINKSELSAGDEG------
----------------VQMLKI-AAISGALPPRL--------------------------
--------------RLRLRITYSKDGSESV-----------TDQVDWSEP----------
-----------------
>gi|47210142|emb|CAF95181.1|	Tetraodon nigroviridis
------------------------------------------------------------
---------------------------------------------MPTVSKGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYTEKQIGYLFISVLV
NSNSDLIRLINNGIKN-----------DLSSRNPTFMNLALHCIANVGSREMAETFASEI
PSILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDW-TARVVHLLNDQH---------L
G---------------------------------------------------------VV
TAAASLITSLA-------------QKSPD--------------DFK---------TSVSL
AVARLSRIVTSASIDLQDYTYYFVAAPWLSVKLLRLLQCY-P------PP----------
------ED---AALRSRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAIALIIHHDR
LVFIEFKGIIQISYYLIVFTSHTCLFWSLSEPTLLVRACNQLGQFLQHR-----------
---ETNLRYLALESMCTLASSEFSHETVKTHIETVINALKTERDVSVRQRAVDLLYAMCD
RSNAKQIVAEMLSYLETA---D--------------------YSIREEIVLKVAILAEKY
AV----DYT--------WYVDTILNLIRIAGDYVSEEVWYRVIQIV--INRD-DVQ----
------GYAAKTVFEALQ-APA---CHE---NLVKVGGYILGEFGNLIA------GD---
---SR--SSPLVQFNLLHSKFHLCSVP-------TRALLLSAYIKFINLFPEVKTT--IQ
GVLRSDSQLRNADVELQQRAVEYLRLSCIA-STDILATVLEEMPPFPERESSILAKLKKK
KGPGNLPDIDDARRNVN----------------------------GSTEHSENTEEA---
-------KKAPS---------------------HPFTDLL--------------------
------------SLSS----------------------------------NSSPG-----
---ANLLVDVFS-DNSAPPSVEVSEEN---------------------------------
----------FHRFVCKNNGVIFENQLLQIGLKSEYRQNLGRIYIFYGNKTSTQF-----
-LSFSSNVNIL--NYSSQ-----LIVHAKTVDPIIEGGAQVQQILNIEC-----------
VSDF---MEAPVLNIQFRYG--GALQNI---AVKLPVMLNKFFQPTEMTSEDFFQRWKQL
GA-PQQEVQKIFRAKHPMDTEVT----KAKILGFGVALLD-RVDPNPANFVGAG------
------------VIH-TKNVQV-GCLLRLEPNTQAQVTHTHTHSTHTHTHTHPHRVRMHT
CVWSHHLTCAPLLCAQMYRLTLRTSRDSVS-----------QRLCDLLSEQF--------
-----------------
>gi|600100|emb|CAA86825.1|	Ustilago maydis
------------------------------------------------------------
-------------------------------------------------MASAGLYNLKA
LIKAIRS-------------------------------CKTLADERSLIQKESASIRTAF
KDE---DPFARHNNIAKLLYIHMLGYPAHFGQIECLKLVATP--RFTDKRLGYLGIMLLL
DENTEVLTLVTNGLKN-----------DMEHSNMYVCGLALCTFANIASEEMSRDLCNEI
EKLMGS--SNTYIRRKAAICAMRIVRKVPDLIDH--F-VDRTQQLLSDKN---------H
G---------------------------------------------------------VL
LCAVTLAIEIC-------------RQDDE-----------ALTVYR---------RAVPL
LVQHLKTLVTTGYS--PEHDVSGITDPFLQVKILRLLRIL--------GK----------
------EN---AQASETMNDILAQVATNTEAS--------KNVGNSILYETVLTILEID-
-----------------------------ADNGLRVMAINILGKFLSNR-----------
---DNNIRYVALNTLSKVVSMD--TNAVQRHRNIILDCLR-DGDISIRRRALELSYALIN
ESNVRVLTRELLSFLEVA---D--------------------NEFKLGMTTQICLAAEKF
AP----NKR--------WHIDTVLRVLKLAGNYVREEILSAFIRLV--CHTP-ELQ----
------AYTVQKLFSGLH-QDF---SQE---SLTLAAVWVIGEFGDVLIQGGNFEDE---
---ELVREVQPKDVVDLLSSVLDSPYVNGL----IRQFVLTSLAKLHTRLSDASQQSRIE
QIIASFE--TSVEVEIQQRSVEFATLLKR---SDIRQGVLESMPPPEIKQTV--------
--LGTVSEAKPVGSTRS-------------------------------------------
----------DK---------------------DALLDLM--------------------
------------GDEM--------------------PVTSGGGTGADNAPSGATQ-----
QSTHDLLADIFGGGDMGGMPSAAPAASASAAQ----------------------------
----------------------------------KPKSSVNDILGLFGDGASAPAAAAQQ
APTPAPAATSSYGGLDLL--------GGLGASSSASTPAATPASTVAKS-----------
HTVY----TKHGLTITLTPT-TNPARPE---IVHITARFTSATSAIS-------------
--------NINFQAAVPKTHKLQ----------MQAISNS-TVHPDSTE-----------
----------------TQPLRV-MVPPG---AAV--------------------------
--------------RLRLRIAFQVDGHSV------------QDQTDWAQPSA--------
-----------------
>gi|109125568|ref|XP_001115458.	Macaca mulatta
------------------------------------------------------------
---------------------------------------------MPAVSKGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYTEKQIGYLFISVLV
NSNSELIRLINNAIKN-----------DLASRNPTFMCLALHCIANVGSREMGEAFAADI
PRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEW-TARVVHLLNDQH---------M
G---------------------------------------------------------VV
TAAVSLITCLC-------------KKNPD--------------DFK---------TCISL
AVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCY-P------PP----------
------ED---AAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYD-
-----------------------------SEPNLLVRACNQLGQFLQHR-----------
---ETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCD
RSNAKQIVSEMLRYLETA---D--------------------YAIREEIVLKVAILAEKY
AV----DYS--------WYVDTILNLIRIAGDYVSEEVWYRVLQIV--TNRD-DVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---PR--SSPPVQFSLLHSKFHLCSVA-------TRALLLSTYIKFINLFPETKAT--IQ
AVLRAGSQLRNADVELQQRAVEYLTLSSVA-STDVLATVLEEMPPFPERESSILAKLKRK
KGPGAGSALDDGRRDPS----------------------------SNDINGGVEPTP---
------STVSTP---------------------SPSADLL--------------------
------------GLRA---------------------------APPPAAPPASAG-----
--AGNLLVDVF--DGPAAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADPGPEDI
GPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQF-----
-QNFSPTVVHP-GDLQTQ-----LAVQTKRVAAQVDGGAQVQQVLNIEC-----------
LRDF---LTPPLLSVRFRYG--GTPQAL---TLKLPVTINKFFQPTEMAAQDFFQRWKQL
SL-PQQEAQKIFKANHPMDAEVT----KAKLLGFGSALLD-NVDPNPENFVGAG------
------------IIQ-TKALQV-GCLLRLEPNAQ--------------------------
--------------AQMYRLTLRTSKEPVS-----------RHLCELLAQQF--------
-----------------
>gi|119910239|ref|XP_584334.3|	Bos taurus
------------------------------------------------------------
---------------------------------------------------MPAPIRLRE
LIRTIRT-------------------------------ARTQAEEREMIQKECAAIRSSF
REE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQ--KFTDKRIGYLGAMLLL
DERQDVHLLMTNCIKN-----------DLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEV
EKLLKT--SNSYLRKKAALCAVHVIRKVPELMEM--F-LPATKNLLNEKN---------H
G---------------------------------------------------------VL
HTSVVLLTEMC-------------ERSPD-----------MLAHFRKNE------KLVPQ
LVRILKNLIMSGYS--PEHDVSGISDPFLQVRILRLLRIL--------GR----------
------ND---DDSSEAMNDILAQVATNTETS--------KNVGNAILYETVLTIMDIK-
-----------------------------SESGLRVLAINILGRFLLNN-----------
---DKNIRYVALTSLLKTVQTD--HNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVN
GNNIRGMMKELLYFLDSC---E--------------------PEFKADCASGIFLAAEKY
AP----SKR--------WHIDTIMRVLTTAGSYVRDDAVPNLIQLI--TNSV-EMH----
------AYTVQRLYKAIL-GDY---SQQ---PLVQVAAWCIGEYGDLLVSGQCEEEE---
---PI--QVTEDEVLDILESVLISNMSTSV----TRGYALTAIMKLSTRFTCTVNR--IK
KVVSIYG--SSIDVELQQRAVEYNALFKKY--DHMRSALLERMPVMEKVT----------
--TNGPTEIVQTNGETD----------------------------PTPLETKPPPSG---
-----PQPTSQA---------------------NDLLDLL--------------------
------------GGND-------------------------ITPVIPTAPTSKPA-----
-SAGGELLDLLG-DIN--------------------------------------------
---------------------------------------------LTGAPAAAPA-----
-PASVPQISQP-PFLLDG-----LSSQ----------PLFNDIATGIPS-----------
ITAY----SKNGLKIEFTFE-RSNTNPS---VTVITIQASNSTE-LDMT-----------
--------DFVFQAAVPKTFQLQ-------------LLSP-SSSIVPAFNTGTI------
----------------TQVIKV-LNPQK---QQL--------------------------
--------------RMRIKLTYNHKGSAMQDL---------AEVNNFPPQSWQ-------
-----------------
>gi|157071379|gb|EAA32041.2|	Neurospora crassa
------------------------------------------------------------
------------------------------------------------------MSSLKQ
FIRNVRA-------------------------------AKTIADERAVIQKESAAIRASF
REES-HDHSVRRNNVAKLLYLFTLGERTHFGQIECLKLLASP--RFADKRLGHLATSLLL
DENQEVLTLVTNSLQK-----------YGAQEDDY------------------GDLFPQI
ETLIST--TNPYIRRKAALCAMRICKKVPDLQEH--F-VEKAAQLLSDRN---------H
G---------------------------------------------------------VL
LCGLTLVTSLC-------------EADEA-----EGGEEGIIEKFR---------QFVPV
LVRTLKGLASSGYA--PEHDVTGITDPFLQVKILRLLRVL--------AR----------
------GD---AQTTEQINDILAQVATNTDAT--------KNVGNSILYEAVLTILDIE-
-----------------------------ADAGLRVLGVNILGKFLANK-----------
---DNNIRYVALNTLVKVVAID--TNAVQRHRNTILECLR-DPDISIRRRALDLSFTLIN
ESNVRVLIRELLAFLEVA---D--------------------NEFKPNMTSQIGIAADRY
AP----NKR--------WHVDTMLRVLTLAGNYVKEPILSSFIRLI--ATTP-ELQ----
------TYAVQKLYTNLK-KDI---TQE---SLTQAGAWCIGEYGDALLRGGQYEEE---
---ELVQEVKEHELIDLFTTILNSNYATQV----TTEYIITALIKLTTRLQDATQIERVR
RLLQYHQ--TSLDVEVQQRAVEYGNLFSF---DQIRRGVLEKMPPPQIKESSRV------
--LGEAAKKTTKAAGKK----------------------------TNKAAK---------
--------PKEE---------------------DLLFDLM--------------------
------------GDTN---------------------------LPSPSVPNGGTN-----
--NADLLADILG-GTTSPPTSASPAPAQSNVA----------------------------
----------------------------------------SIMDLFSQGPTSTPS-----
-PAPAPAAAPS-AVLDLF--------NTTPAAASAPAPQAAPKPAAAAG-----------
HACY----DNNGLNVTIQIQ---RNAEG---MIQATARFRNSFPGGPLS-----------
--------AVGLQAAVPKSQKLQ-------------LLNISSTDIAPGAEA---------
----------------TQMMRVAGCTGAL-------------------------------
--------------RLRLKIGYTHPTAGQV-----------LDLVNWTEPS---------
-----------------
>gi|115389394|ref|XP_001212202.	Aspergillus terreus
------------------------------------------------------------
------------------------------------------------------MTSLKQ
FIRNVRS-------------------------------AKTIADERAVIQKESAAIRASF
REES-HDSGIRRNNVAKLLYLFTLGERTHFGQIECLKLLASH--RFADKRLGYLGTMLLL
DENQEVLTLVTNSLKKTCADVVFPECSDLNHSNQYIVGLALCALGNIASVEMSRDLFPEV
ENLLST--ANPYIRRKAALCAMRICRKVPDLQEH--F-LEKAKQLLSDRN---------H
G---------------------------------------------------------VL
LCGLTLVIDMC-------------EAEEA-----EEGQEGVIEMFR---------PLAGG
LVRALKGLTTSGYA--PEHDVSGITDPFLQVKILRLLRVL--------GR----------
------GD---VATSELINDILAQVATNTDSS--------KNVGNSILYEAVLTILDIE-
-----------------------------ADSGLRVLGVNILGKFLTNK-----------
---DNNIRYVALNTLNKVVAIE--PNAVQRHRNTILECLR-DPDISIRRRALDLSFMLIN
EGNVRVLVRELLAFLEVA---D--------------------NEFKPAMTTQIGIAADRF
AP----NKR--------WHVDTILRVLKLAGAYVKEQILSSFVRLI--ATTP-ELQ----
------TYSVQKLYMSLK-DDI---SQE---GLTLAATWVIGEYGDSLLRGGQYEEE---
---ELVKEVQESDIVDLFNNILNSTYASQT----VVEYITTASMKLTVRMSDPSQIERLR
RFLLSRT--ADLSVEIQQRAVEYSNLFGY---DQIRQGVLERMPAPEIREEQRV------
--LGAPTKKRQSKVLKD----------------------------KTKK-----------
-----PAKQAEQ---------------------DMLLDLM--------------------
------------GGDA-----------------------------PATSPTGNTS-----
QNTADLLADILGGDSGMSSPAPQPAQQPA-------------------------------
------------------------------------QSNTAAIMDLFGSNGASAT-----
-PSPQPTQPASSLDLLGG-----LGSSTS--------PAPAASAAAAPA-----------
HTAF----DKNELSLTLQVQ---RSGPN---NAQIQARFRNASNFGSFS-----------
--------GVGLQAAVPKSQRLQ---------------LS-AINKADLEGGDEG------
----------------IQMLKV-TALSGALPPKL--------------------------
--------------RLRLRITYAKDGSAPV-----------TDQVDWTEP----------
-----------------
>gi|125985355|ref|XP_001356441.	Drosophila pseudoobscura
------------------------------------------------------------
----------------------------------------------MAPVRGDGMRGLAV
FISDIRN-------------------------------CKSKEAEVKRINKELANIRSKF
KGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYSEKQIGYLFISVLV
NTNSDLIRLIIQSIKN-----------DLQSRNPVHVNLALQCIANIGSRDMAESFSNEI
PKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEW-TSRIIHLLNDQH---------M
G---------------------------------------------------------VV
TAATSLIDALV-------------KCNPD--------------EYK---------GCVNL
AVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNP------VT----------
------EE---AGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSD-
-----------------------------SEPNLLVRACNQLGQFLSNR-----------
---ETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCD
RGNAEEIVQEMLNYLETA---D--------------------YSIREEMVLKVAILAEKY
AT----DYT--------WYVDVILNLIRIAGDYVSEEVWYRVIQIV--INRE-EVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---SR--SAPLVQFKLLHSKYHLCSPM-------TRALLLSTYIKFINLFPEIRTN--IQ
DVFRQHSNLRSADAELQQRASEYLQLSIVA-STDVLATVLEEMPSFPERESSILAVLKKK
K-PGRVPEN-EIRESKS----------------------------PAPTSGPGSVLQNNV
HVNNSHSKLNNS---------------------NANTDLL--------------------
------------GLST---------------------------PPANNVGSNSNS-----
-----TLIDVLG-DIYGSNNNSSAVYNT--------------------------------
-----------KKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFYGNKTQVPL-----
-SNFNPVLQWS-AEETLK-----LNVQMKAVEPTLEAGAQIQQLLTAEC-----------
IEDY---ADAPTIEISFRYN--GTQQKF---SIKLPLSVNKFFEPTEMNAESFFARWKNL
SG-EQQRSQKVFKAAQPLDLPGA----RNKLMGFGMQLLD-SVDPNPDNMVCAG------
------------IIH-TQSQQV-GCLMRLEPNKQ--------------------------
--------------AQMFRLTVRASKETVT-----------REICDLLADQF--------
-----------------
>gi|28277340|gb|AAH45070.1|	Xenopus laevis
------------------------------------------------------------
---------------------------------------------QQYRARMPAPIRLRE
LIRTIRT-------------------------------ARTQAEEREMIQKECAAIRSSF
REE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQ--KFTDKRIGYLGAMLLL
DERQDVHLLMTNCIKN-----------DLNHSTQYVQGLALCTLGCMGSAEMCRDLAGEV
EKLLKT--SNSYLRKKAALCAVHVIRKVPELMEM--F-LPATKNLLNEKN---------H
G---------------------------------------------------------VL
HTSVVLLTEMC-------------ERSPD-----------MLTHFR---------KLVPQ
LVRILKNLIMSGYS--PEHDVSGISDPFLQVRILRLLRIL--------GR----------
------ND---DDSSEAMNDILAQVATNTETS--------KNVGNAILYETVLTIMDIK-
-----------------------------SESGLRVLAINILGRFLLNN-----------
---DKNIRYVALTSLLKTVQTD--HNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVN
GNNIRGMMKELLYFLDSC---E--------------------PEFKADCASGIFLAAEKY
AP----SKR--------WHIDTIMRVLTTAGGYVRDDAVPNLIQLI--TNST-EMH----
------EYTVQKLYKAIL-DDI---SQQ---PLVQVSSWCIGEYGDLLVSGQCEEEE---
---PI--QVTEDEVLDILESILISNMSASV----TRGFALTAIMKNSTRFNSTVNR--IK
KVVSIYG--SSIDVELQQRAVEYNALFKKY--DHMRSALLERMPVMEKTM----------
--TNGPTDLAQTNGETD----------------------------PTIIDAKPVQST---
-----PQPSSQA---------------------NDLLDLL--------------------
------------GGND-------------------------IQLVIPTALPSKPA-----
-SVGGELLDLLG-DLNLSGT----------------------------------------
------------------------------------------------------------
-PAAVPQMPAP-QLLLDG----------------LSAQPLFNDIAGIPP-----------
ITAY----NKNGLKIDFSFE-RSSTNAS---ITVITTQASNCTD-SDMT-----------
--------EFVFQAAVPKTFQLQ-------------LLSP-SSNVLPAFNAGSI------
----------------TQVIKV-LNPQK---QQL--------------------------
--------------RMRVKLTYNHKGSAIQDL---------AEVSNFPPQSWQ-------
-----------------
>gi|126304839|ref|XP_001367280.	Monodelphis domestica
------------------------------------------------------------
---------------------------------------------------MPAPIRLRE
LIRTIRT-------------------------------ARTQAEEREMIQKECAAIRSSF
REE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQ--KFTDKRIGYLGAMLLL
DERQDVHLLMTNCIKN-----------DLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEV
EKLLKT--SNSYLRKKAALCAVHVIRKVPELMEM--F-LPATKNLLNEKN---------H
G---------------------------------------------------------VL
HTSVVLLTEMC-------------ERSPD-----------MLAHFRKNE------KLVPQ
LVRILKNLIMSGYS--PEHDVSGISDPFLQVRILRLLRIL--------GR----------
------ND---DDSSEAMNDILAQVATNTETS--------KNVGNAILYETVLTIMDIK-
-----------------------------SESGLRVLAINILGRFLLNN-----------
---DKNIRYVALTSLLKTVQTD--HNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVN
GNNIRGMMKELLYFLDSC---E--------------------PEFKADCASGIFLAAEKY
AP----SKR--------WHIDTIMRVLTTAGSYVRDDAVPNLIQLI--TNSV-EMH----
------AYTVQRLYKAIL-GDY---SQQ---PLVQVAAWCIGEYGDLLVSGQCEEEE---
---PI--QVTEDEVLDILESVLISNMSTSV----TRGYALTAIMKLSTRFSCTVNR--IK
KVVSIYG--SSIDVELQQRAVEYNALFKKY--DHMRSALLERMPVMEKVT----------
--TNGPTDIVQTNGETE----------------------------PAPLETKPPPSG---
-----PQPTNQA---------------------NDLLDLL--------------------
------------GGND-------------------------ITPIIPTVPTSKPA-----
-SAGGELLDLLG-DLNLAGAPPSA------------------------------------
------------------------------------------------------------
-PASVPQLSQP-PFLLDG-----LSSQ----------PLFNDIASGIPS-----------
ITAY----SKNGLKIEFTFE-RSNTNPS---VTVITIQASNSTE-LDMT-----------
--------DFVFQAAVPKTFQLQ-------------LLSP-SSSIVPAFNTGTI------
----------------TQVIKV-LNPQK---QQL--------------------------
--------------RMRIKLTYNHKGSAMQDL---------AEVNNFPPQSWQ-------
-----------------
>gi|91092680|ref|XP_971368.1|	Tribolium castaneum
------------------------------------------------------------
----------------------------------------------MPAVRGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYSEKQIGYLFISVLV
NTNSELIKLIIQSIKN-----------DLASRNPIHVNLALQCIANIGSREMAEAFGNEI
PKLLVSGDTMDVVKQSAALCLLRLFRTSQEIIPGGEW-TSRIIHLLNDQH---------M
G---------------------------------------------------------VV
TAATSLIDALV-------------KKNPE--------------EYK---------GCVSL
AVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYTP------PA----------
------ED---PGVRGRLNECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHND-
-----------------------------SEANLLVRACNQLGQFLSNR-----------
---ETNLRYLALESMCHLATSEFSHEAVKKHQEVVILSMKMEKDVSVRQQAVDLLYAMCD
KSNAEEIVQEMLNYLETA---D--------------------YSIREEMVLKVAILAEKY
AT----DYT--------WYVDVILNLIRIAGDYVSEEVWYRVIQIV--INRD-EVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---QR--SSPSVQFQLLHSKYHLCSPM-------TRALLLSTYIKFINLFPEIRTQ--VQ
EVFKQHSNLRSADAELQQRASEYLQLSIIA-SSDVLATVLEEMPAFPERESSILAVLKKK
K-PGRVPEN-EIKENKS----------------------------PTPVTNHNNDVN---
---------NSS---------------------AVSGDLL--------------------
------------GLST----------------------------PPTAQPNSGNT-----
----GVLLDVLG-DIYGGKQANNSNSATQPVN----------------------------
-------MYNPKKFVCKNNGVLFESDLIQIGVKSEFRQNLGRLGLFYGNKTNVPL-----
-QNFVPTLSWP-DDQASK-----LTIQMKPVEPVLEAGAQIQQMINAEC-----------
VDDY---TGAPSIVLSFLYL--NVPQKI---TIKLPLTINKFFEPTEMNGESFFARWKNL
GSTNQQRSQKIFRATQQMDLQAA----RTKIMGFGMQLLD-GIDPNPDNFVCAG------
------------IIH-MRSQQV-GCLLRLEPNKS--------------------------
--------------AQMYRLTVRSSKESVS-----------IEICDLLADQF--------
-----------------
>gi|41054423|ref|NP_955976.1|	Danio rerio
------------------------------------------------------------
---------------------------------------------------MPAPIRLRE
LIRTIRT-------------------------------ARTQAEEREMIQKECAAIRSSF
GEE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQ--KFTDKRIGYLGAMLLL
DERQDVHLLMTNCIKN-----------DLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEV
EKLLKT--SNSYLRKKAALCAVHVIRKVPELMEM--F-LPATKNLLSEKN---------H
G---------------------------------------------------------VL
HTSVVLLTEMC-------------ERSPD-----------MLSHFR---------KLVPQ
LVRILKNLIMSGYS--PEHDVSGISDPFLQVRILRLLRIL--------GK----------
------GD---DDSSEAMNDILAQVATNTETS--------KNVGNAILYETVLTIMDIK-
-----------------------------SESGLRVLAVNILGRFLLNN-----------
---DKNIRYVALTSLLKTVQAD--HNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVN
GNNIRGMMKELLYFLDSC---D--------------------PEFKADCASGIFLAAEKY
AP----SKR--------WHIDTIMRVLTTAGSYVRDDSVPNLIQLI--TNSV-EMH----
------AYTVQRLYKALL-DDI---SQQ---PLVQVASWCIGEYGDLLVSGQCEEEE---
---PI--QVSEDEVLDVLEGLLVSNLSAPV----TRGYSLTAIMKLSTRFSSVNR---IK
KVVSIYG--SSIDVELQQRAVEYNALFKKY--DHMRPALLERMPIMEKSA----------
--TNGPAEIVQTNGETD----------------------------APILDTKHPPNI---
-----PQPISQA---------------------NDLLDLL--------------------
------------GGND-------------------------VVPVIQTTAPTKPA-----
-SAGGELLDLLG-DLS--------------------------------------------
---------------------------------------------LTGGPAPTPA-----
---PSVPMSQP-PFLLDG-----LTSQ----------PLFNDIGAGIPP-----------
MTAY----NKNGLKIEFTFE-RSNPNPN---IAVITIHATNTTE-VDMT-----------
--------EFVFQAAVPKTFQLQ-------------LLSP-SSNVVPALNQGSV------
----------------TQVIRV-LNPQK---QQL--------------------------
--------------RMRIKLTYTHKGSPVQDL---------AEVNNFPPQSWQ-------
-----------------
>gi|114652181|ref|XP_522804.2|	Pan troglodytes
------------------------------------------------------------
--------------------------------------------------MVVPSLKLQD
LIEEIRG-------------------------------AKTQAQEREVIQKECAHIRASF
RDG---DPVHRHRQLAKLLYVHMLGYPAHFGQMECLKLIASS--RFTDKRVGYLGAMLLL
DERHDAHLLITNSIKN-----------DLSQGIQPVQGLALCTLSTMGSAEMCRDLAPEV
EKLLLQ--PSPYVRKKAILTAVHMIRKVPELSSV--F-LPPCAQLLHERH---------H
GKAVGPPILCFRSMDRRIENRMGTPAHRRMVVHTHRHTRNRLSCPWPPPFTSPTLTPGIL
LGTITLITELC-------------ERSPA-----------ALRHFR---------KVVPQ
LVHILRTLVTMGYS--TEHSISGVSDPFLQVQILRLLRIL--------GR----------
------NH---EESSETMNDLLAQVATNTDTS--------RNAGNAVLFETVLTIMDIR-
-----------------------------SAAGLRVLAVNILGRFLLNS-----------
---DRNIRYVALTSLLRLVQSD--HSAVQRHRPTVVECLR-ETDASLSRRALELSLALVN
SSNVRAMMQELQAFLESC---P--------------------PDLRADCASGILLAAERF
AP----TKR--------WHIDTILHVLTTAGTHVRDDAVANLTQLI--GGAQ-ELH----
------AYSVRRLYNALA-EDI---SQQ---PLVQVAAWCIGEYGDLLLAGNCEEIE---
---PL--QVDEEEVLALLEKVLQSHMSLPA----TRGYALTALMKLSTRLCGDNNR--IR
QVVSIYG--SCLDVELQQRAVEYDTLFRKY--DHMRAAILEKMPLVE-------------
--RDGPQADEEAKESKE----------------------------AAQLSE-AAPVP---
-------TEPQA---------------------SQLLDLL--------------------
------------DLLD-----------------------------------GASG-----
-------------DV---------------------------------------------
------------------------------------------------------------
-QHPPPLDPSP-GGALIH---------------LLDLPCVPPPPAPIPD-----------
LKVF----EREGVQLNLSFI-RPPENPA---LLLITVTATNFSE-GDVT-----------
--------HFICQAAVPKSLQLQ-------------LQAP-SGNTVPARGGLPI------
----------------TQLFRI-LNPNK---APL--------------------------
--------------RLKLRLTYDHFHQSVQEI---------FEVNNLPVESWQ-------
-----------------
>gi|151942818|gb|EDN61164.1|	Saccharomyces cerevisiae
------------------------------------------------------------
-----------------------------------------------------MGSSLRS
FIKDVRG-------------------------------AKTLADERAIITKQSAKIRTKL
RDDH-LPHEKRRVNIQKLLYLYILGEKTHFGQVESINLIASD--DFVDKRLGYLAATLLL
DESEDLLTLLTNMLNN-----------DLHHPNKYAVSLALTSLGFLSSPELARDLYPDV
ENIIKN-SRDPFLLKKALQCAAKLIFKDVSLLEI--FNIEDITKILSSHS------ICTH
G---------------------------------------------------------VL
LGVTKIIQSIL-------LIGLNRKKDEDEDEDGIDYSNDILSPLS---------LLLRD
FFIRLENMNSKNIE--PGYDVQGICDPFLQCEIIYTLKLYFQVGELLNSN----------
------NV---LDYKDNFCDLLTRIATNTDST--------KNSGQAILYETVKTIFSLD-
-----------------------------LNQPLRVLGINILAKFLAGK-----------
---DNNTKYVSLNTLLKVVPQE--PTAVQRHRKFISHCLQ-DTDVSIRMRALELSFAILD
DSNLVELVNELMKFLAKQ---D--------------------EDSKDLIIYTIDHLIDTF
DTRVVKDES--------WKLDVFFNILKLVGSFINYEKINDILIII--NNTS-QLSDKS-
------EFLRKILTISLN-GTSAEISEE-NIGWQLVLIWCIGEYGDLVLNEGNKNGA---
---DIINESSITDYLLTLQELYTATNLK------IINYILTAALKLSVRFHDAKNIEKLR
QLILSYT--DSTDLSLQMKSNQYEIFFNQS--ISVKKIILETMPKFEKITEE--------
--QDNGKALSKNLISNE----------------------------PV-------------
---------------------------------DLLSDLL--------------------
------------GEDS---------------------------KAESKASTGDNV-----
-----KPIDILE-EI---------------------------------------------
----------------------------------------------FGEKNDIA------
---QVPKNANK-EESINH---------------SSAVEANSGVTLPLDA-----------
NKIY----DSSSLNVYAS---LLSANSG---LAHLDLYFQAKSLISDLK-----------
--------TFC---AVPKAQKLT----------LGQLYPS-STIN----ASQIC------
----------------KQSLKI-SGSGK-----L--------------------------
--------------KLRVKLDFHLNGSS-------------SITNEQFDHKFDETL----
-----------------
>gi|50292039|ref|XP_448452.1|	Candida glabrata
------------------------------------------------------------
-------------------------------------MMRRSSSKKGSSGTYNGSSSLRN
FIKDVRN-------------------------------AKTLADERAIINKQAAKIRTKL
RDDH-LSSDKKRNNIIKLLYLYILGERTHFGQVECINLIASD--QYIDKRLGYLSTTLLL
DESQDLLTLLTNLINN-----------DLKHPNKYVVSLALTALGFLSSPELARDLYPDV
EGLLKTYSTDPYILKKALQCCAKLIAKDSQLLEI-VP-IDLFLTLLKEYRSSLTSLSAAH
G---------------------------------------------------------VL
IGLSRLFQAIATAITNLVTPQETSESDPEDMAYRQNLAQQMIKIFSES-------SFLDD
FYQVLASLSSRNLD--PQFDVQGVSDPFLQCEVITTLRLYFKAYHKLATE----------
------IN---QEQVDGFNDLLTNIATNTDST--------KSSGQAVLYEITRTIFDLQ-
-----------------------------LPKPLQVLGINILGNFLSPRSVGGKKPTTAV
ITAQNNTKYVALNMLLKVVPSE--PEAVRRHRKFISRCLN-DQDISIRMRALELTFAIMD
KDNLVELINEVLNFLAKSVMNNGSAKGGYSSSYKINSFGEDIDDSKDLIIFAVNHIVDKF
GE---ISEEQGENIDNNWRLSVFVKILKLVGSYIPVDRISDILIAF--NNTL-EVNYKTD
VIIRMLDISLREVMESTDKTTEDEFIEEGNLGWQLVSIWCIGEYGDIVLQALQSDSKLNE
TYGKTINEKTIVNYLKLKDTQYIRTNLK------INHYVLTAALKLSVRIQDFALIEKLR
QIIVGQT--KNTDLLLQAKATQYEIIFSQP--ESIRKQILDAMPQFERAVKT--------
--EKPVTSISHLDNGKQ----------------------------SDRKH----------
---------------------------------DPLLDLL--------------------
------------GDTD-----------------------------VQDTKQQQKN-----
------NTNLLA-DLL--------------------------------------------
----------------------------------------------LGENNNGIQ-----
-SQGQTSKNNE-DKLTL--------------------PESCTLLQTIDC-----------
LEIY--------------AS-KITKDDT---SAHLEIYYKNNGD-VEVS-----------
--------NLQCLVAVTKTLKVV----------LGQLYPS-VNIP----ANGII------
----------------KQTLKV-SGTGN-----L--------------------------
--------------KMRVKLSYSVGGS--------------QQTQQFDHKFPELTL----
-----------------
>gi|58269254|ref|XP_571783.1|	Cryptococcus neoformans
------------------------------------------------------------
--------------------------------------------------MATQMRGLTQ
YISDLRA-------------------------------CRVRELEEKRINREMAHIRQKF
KDGN-LDGYQKKKYLAKVVFTYILGYKVDVGHMEAINLISSQ--KYSEKQIGYLALTLLM
HENSDLARLVINSLHK-----------DLEDQNEVNNCLALHAIATLGGKEMAEALAESV
YRSMISATSSTFVKKKAALTLLRLYRKHPSVMPIKEW-AARIVSMMGDRD---------P
G---------------------------------------------------------VV
LTITALVTTMA-------------QAELE--------------AFS---------GSYQK
AVDILDRIVFEGHYP-AEYVYYKVPNPWLQTKLLRLLQYY-P------PPGTYFFSPIQN
PADNYLDN---PQVVEMVNSIIQAIIDSSQDTPRN--VQHNNAQNAVLFESINLAIHID-
-----------------------------PSSQVVQNASVLLGRFILAK-----------
---ETNVRYLGLDAMAHLAATSNSLGAVKKHQNVIIQGLK-DRDISVRRRALDLLYSMCD
TSNAKVIVGELVRYLQVA---D--------------------YNLREDMVLKIAILTERF
AT----EYE--------WYVDTILQLIAAAGDHVGAEVWYRVVQLV--VNNE-GVQ----
------DYAVRAVYKHLQ-ATA---CHE---NMIRVGGYIMGEFGHLIA------ND---
---PG--SSPIEQFQALHSKVNLCTAP-------TRALLLSTYIKWVNLFPEIKEH--LI
NIFERYT--HVLDAELQQRACEYLALARRSESDDLLATICDEMPVFPERESALLSRLHRK
G-EMAQDKRTWVIGGREE-NNLREAERFKAFRKGTGDSGGIVSGSPAPASTAPSPAATAG
TSAVTPSPAPDSYSAPQRHASVNTETMMGVASSGPSEDIISSLSDLDLTGSHVQNQPLLT
SAPTGAYSQELAGLQM-------------------QPTGAGGAPLLNGQADGSNG-----
------INGMNG-DRGLAYSATLGGVNPALLA------------------------PLTV
---ADGVEKWFERLSFSNEGVLYEDTLIQIGVKAEYHGHLGRIALFFGNKADQPF-----
-TSFSALIDNP-SPSAIN-----IHFHDSPVG-EVRAKAQIQEMIHVEC-----------
REVFFREGGTPLLRLSFLVG--EERKIL---VLKLPVFLSKFAEGVHLESGPFFERWKII
GG-PPREAQQIFPIKLTANGMVDIGRNQRVITGNKLSVLP-DIDHKPENIVFAG------
------------VLHMSSAGKV-GILGRVEPNKD--------------------------
--------------AKLCRLTVRSTNEHVS-----------AEILSLTSKPLNADIAASL
-----------------
>gi|68480456|ref|XP_715826.1|	Candida albicans
------------------------------------------------------------
------------------------------------------------------MASLKS
FIKSVRK-------------------------------AKTIADERSVVQKESAAIRTSF
RDPG-LDQTTRRINISKLLYLYIMGEKTHFGQVECLKLLASP--RFADKRLGYLACMLIL
DENQEVLTLLTNSLDN-----------DMQHPNSFIVGLALCCLGNIASPELARDLYTNV
ETIIDS--KNVYLKKKACIVAAKLIEKEPELAEF--F-ITKINSLINEKQ---------P
S---------------------------------------------------------LL
LGTIRLIQALY-------------FASEE-----------SRSTLI---------KTIPK
LVADLKRTTTSGYQ--PDYDVTGTTDPFLQVSLLETLRIL--------GR----------
------DEQCPPQYLEQINDILTQVASNLDSG--------KNAAHAILYECVKTIFAIQ-
-----------------------------SDQSLKILGVNILGKFLSTK-----------
---DNNTRYVALDTLLTVVTIE--PMAVQRHRSTIVNCLS-DGDISIRRRALELSFGILN
EQNIRVLAREILTFLEKC--HD--------------------QELKSYVTSQLTIAANKY
AP----NDK--------WHFDTLIRMLKVGGNALTPDIISNILALILQCNDL-ELK----
------KHVASKLVASCL-ETT---NQY---GLALITSWTMGEYGDLIL-GTNVEVN---
---GKTIIITEQKLSQLIDDLINNTNFSESETIQLTSYILTSIIKLSIKFKDNQVIETLR
LILNSKT--HDPNLEIQTRAVEYQQIFGQD--STLKRGLLARMPAPPVKQREALTLHKS-
--ANTTTTNTHKSLKKS----------------------------TNETSGGGSGSD---
---------------------------------NLLLDLM--------------------
------------DDIV-----------------------------SPASNQQQSS-----
-QQGDVISDIFGGGGGSGN-----------------------------------------
------------------------------------------------------------
-DTNKSTINNA-AILDLF---------------NSSSNSINPAVSSVSE-----------
IPAF----ENNDVKISFIPK--SFPQNG---EATIEAIIRSKINDSNIN-----------
--------QFQLLIAVPKSQKLT-----ITSTSGGDSLIG-SSNPNESI-----------
----------------RQILKI-VGKQG---AKI--------------------------
--------------KLRVKVKYNINNSNSV-----------EEQFDFAGFKSNL------
-----------------
>gi|66511475|ref|XP_394621.2|	Apis mellifera
------------------------------------------------------------
----------------------------------------------MPAVRGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYSEKQIGYLFISVLV
NTNSDLIKLIIQSIKN-----------DLASRNPIHVNLALQCIANIGSKEMAEAFGNEI
PKLLVSGDTMDVVKQSAALCLLRLLRTAPDVVPGGEW-TSRIVHLLNDQH---------L
G---------------------------------------------------------VV
TAAASLIDALV-------------KRNPD--------------EYK---------GCVSL
AVSRLSRIVTSSYTDLQDYTYYFVPAPWLSVKLLRLLQNYTP------PA----------
------ED---PGVRGRLNECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHND-
-----------------------------SELPLSVRACNQLGQFLSNR-----------
---ETNLRYLALESMCHLATSELSHEAVKKHQEVVILSMKMEKDVSVRQQAVDLLYAMCD
KSNAEEIVQEMLNYLETA---D--------------------YSIREEMVLKVAILAEKY
AT----DYT--------WYVDVILNLIRIAGDYVSEEVWYRVIQIV--INRE-DVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---QR--SSPAVQFQLLHSKYHLCSPM-------TRALLLSTYIKFVNLFPEMRSQ--IQ
DVFRQHSNLRSADAELQQRASEYLQLSIIA-SSDVLATVLEEMPAFPERESSILAVLKRK
K-PGRVPEN-EIRESKS----------------------------PAPNTNHHAEAPSS-
------VTGAVN---------------------NTSADLL--------------------
------------SLST----------------------------PPSSQPSSNTG-----
-----VLLDVLG-DIYNMPNKVATNGAQNTYN----------------------------
----------PKKFVCKNNGVLFESELIQIGVKSEFRQNLGRVGLFYGNKTQYAL-----
-HSFQPQLSWS-EENQQK-----LAVQVKPVDPVLEAGAQIQQMINAEC-----------
IDDY---SDAPSMIISFIYN--NVPQKI---TMKLPLTINKFFEPTEMNGESFFARWKNL
GGANQQRSQKIFKAQQPMDLTQV----RTKLQGFGMQLLD-GIDPNPDNFVCAG------
------------IVH-MRAQQV-GCLLRLEPNKQ--------------------------
--------------AQMFRLTVRSSKESMS-----------VEICDLLVDQF--------
-----------------
>gi|149411842|ref|XP_001509404.	Ornithorhynchus anatinus
------------------------------------------------------------
---------------------------------------------------MPAPIRLRE
LIRTIRT-------------------------------ARTQAEEREMIQKECAAIRSSF
REE---DNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQ--KFTDKRIGYLGAMLLL
DERQDVHLLMTNCIKN-----------DLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEV
EKLLKT--SNSYLRKKAALCAVHVIRKVPELMEM--F-LPATKNLLNEKN---------H
G---------------------------------------------------------VL
HTSVVLLTEMC-------------ERSPD-----------MLAHFRKNE------KLVPQ
LVRILKNLIMSGYS--PEHDVSGISDPFLQVRILRLLRIL--------GR----------
------ND---DDSSEAMNDILAQVATNTETS--------KNVGNAILYETVLTIMDIK-
-----------------------------SESGLRVLAINILGRFLLNN-----------
---DKNIRYVALTSLLKTVQTD--HNAVQRHRSTIVDCLK-DLDVSIKRRAMELSFALVN
GNNIRGMMKELLYFLDSC---E--------------------PEFKADCASGIFLAAEKY
AP----SKR--------WHIDTIMRVLTTAGSYVRDDAVPNLIQLI--TNSV-EMH----
------AYTVQRLYKAIL-GDY---SQQ---PLVQVAAWCIGEYGDLLVSGQCEEEE---
---PI--QVTEDEVLDILESVLISNMSTSV----TRGYALTATMKLSTRFTCTVNR--IK
KVVSIYG--SSIDVELQQRAVEYNALFKKY--DHMRSALLERMPIMEKTT----------
--TNGPTEIVQTNGETE----------------------------PAVLETKPPPTG---
-----PQPTSQA---------------------NDLLDLL--------------------
------------GGND-------------------------ITPVIPTAPTSKPA-----
-SAGGELLDLLG-DLN--------------------------------------------
---------------------------------------------LTGAPASAPA-----
-SAPVPQISQP-PFLLDG-----LSSQ----------PLFNDIAAGIPS-----------
ITAY----SKNGLKIEFTFE-RSNTNPS---VTVITIQASNSTE-LDMT-----------
--------DFVFQAAVPKTFQLQ-------------LLSP-SSSIVPAFNTGTI------
----------------TQVIKV-LNPQK---QQL--------------------------
--------------RMRIKLTYNHKGSAMQDL---------AEVNNFPPQSWQ-------
-----------------
>gi|83775310|dbj|BAE65432.1|	Aspergillus oryzae
------------------------------------------------------------
---------------------------------------------------MSSMRGLVQ
FIADLRN-------------------------------ARARELEEKRVNKELANIRQKF
KGGS-LNGYQKKKYVCKLLYVYIQGYDVDFGHLEAVNLISST--KYSEKQIGYLAVTLFF
HEQHELLHLVVNSIRK-----------DLLDHNELNNCLALHAVANVGGREMGEALSTDV
HRLLISPTSKAFVKKKAALTLLRLYRKYPGIVQI-EW-AERIISLMDDPD---------M
G---------------------------------------------------------VT
LSVTSLVMALV-------------QDKPE--------------EYR---------GSYVK
AAQRLKRIIVDNDIA-PDYLYYRVPCPWIQVKLLRLLQYY--------PP----------
------------HVREIIRESLQQIMNIAMDTPKN--VQQNNAQNAVLFEAINLLIHLD-
-----------------------------TEHSLMMQVSSRLGKYIQSR-----------
---ETNVRYLGLEAMTHFAARAETLDPIKKHQNIILGSLR-DRDISVRRKGLDLVYSMCD
TTNAGPIVNELLRYLQTA---D--------------------YGIREEMVLKVAILTEKY
AT----DAQ--------WYIDMTLKLLSLAGDHVNDEVWQRVIQIV--TNNE-ELQ----
------AYAAHTLLNYLK-TD----CHE---SLVKIGCYVLGEFGHLIA------DN---
---QG--SSPIEQFLALQAKMITSTDN-------TRAMILSSFIKFVNLFPEIKPQ--LL
HIFRLYS--HSPDSELQQRAFEYLSLATLP-TDDLLRTVCDEMPPFSERASILLSRLHQK
T-AGTTDKKTWVVGGKD----------------------------ANQDQK---------
-----------E---------------------VLMAQNT--------------------
------------GLKR------------------------TFTTIVNGTSTGTNG--TAA
SPASSATGDLAGLDLSASSAPPPPNMASAAHL----------------------------
---TPDWDIGYNRLYFKEQGVLFEDAQIQVGLRSEYRGHMGVVKIYISNKSSFPI-----
-GSLTTTLDNR-AAPNLK-----IDSKSLP-EPSVPAAGQTQQTFFFEA-----------
NGPF---TDAPTIRISYLAG---ALQAY---TLQLPVLMHRYMEPSTLSAEEFFKRWRQI
GG-PPLEAQNTF-GVVAKAKDINESFTRQTVEGFGWRIVD-NVDPNPKNIVGCA------
------------VFH-FGTGKT-GCLLRLEPNYE--------------------------
--------------KMMYRITIRATQEAVP-----------QALAKQMEQKLAQGKTGST
PDLFSSPEVFTCTNTRN
>gi|148231263|ref|NP_001090846.	Xenopus tropicalis
------------------------------------------------------------
---------------------------------------------MPAVSKGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYTEKQIGYLFISVLV
NSNSELIRLIINAIKN-----------DLASRNPTFMCLALHCIANVGSREMAEAFASEI
PRILVAGDTMDSVKQSAALCLLRLYKTSPDLVPMGEW-TSRVVHLLNDQH---------M
G---------------------------------------------------------VV
TAAVSLITCLC-------------RKNPD--------------DFK---------TCVSL
AVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCY-P------PP----------
------ED---AAVKGRLVECLETILNKAQEPPKSKKVQHSNAKNAILFEAISLIIHYD-
-----------------------------SEPNLLVRACNQLGQFLQHR-----------
---ETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAADLLYAMCD
RTNAKQIVSEMLSYLETA---D--------------------YSIREEIVLKVAILAEKY
AV----DYS--------WYVDTILNLIRIAGDYVSEEVWYRVIQIV--INRD-DVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---PR--SSPLVQFNLLHSKFHLCSVS-------TRALLLSTYIKFINLFPETKTT--IQ
DVLRSDSQIRNADVELQQRAVEYLKLSSIA-STDVLATVLEEMPPFPERESSILAKLKKK
KGPGAVSDLEEGKKDQN-----------------------------SEINGGVEPTP---
------STASTP---------------------SPSADLL--------------------
------------GLRS-----------------------------TAVTSSAAPS-----
--AGSLLVDVFS-DSPTSSVPVAPGAEENFLS-------------------SGSAASEDP
ALPIAEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQF-----
-QSFTPTVNYP-GELQSQ-----VNIQTKPVDPVVEGGAQVQQVLNIEC-----------
LSDF---DEAPLINIKFRYG--GTLQNI---TLKLPITVNKFFQATEMPSQDFFQRWKQL
SL-PQQEAQKIFKANHPMDSEVT----KAKLLGFGTALLD-KVDPNPDNYVGAG------
------------IVQ-TKSIQV-GCLLRLEPNIQ--------------------------
--------------AQMYRLTLRTSKEAVS-----------KHLCELLSKQF--------
-----------------
>gi|148690825|gb|EDL22772.1|	Mus musculus
------------------------------------------------------------
--------PALPRPAPRRRLGSFPPGAASQPRARSARLGAEPSAIMPAVSKGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYTEKQIGYLFISVLV
NSNSELIRLINNAIKN-----------DLASRNPTFMCLALHCIANVGSREMGEAFAADI
PRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEW-TARVVHLLNDQH---------M
G---------------------------------------------------------VV
TAAVSLITCLC-------------KKNPD--------------DFK---------TCISL
AVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCY-P------PP----------
------ED---AAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYD-
-----------------------------SEPNLLVRACNQLGQFLQHR-----------
---ETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCD
RSNAKQIVSEMLRYLETA---D--------------------YAIREEIVLKVAILAEKY
AV----DYS--------WYVDTILNLIRIAGDYVSEEVWYRVLQIV--TNRD-DVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---PR--SSPPVQFSLLHSKFHLCSVA-------TRALLLSTYIKFINLFPETKAT--IQ
GVLRAGSQLRNADVELQQRAVEYLTLSSVA-STDVLATVLEEMPPFPERESSILAKLKRK
KGPGAASALDDSRRDTS----------------------------SNDINGGVEPTP---
------STVSTP---------------------SPSADLL--------------------
------------GLRA---------------------------APPPAAPPAPVG-----
---GNLLVDVFS-DGPTAQPSLGPTPEEAFLSELEPPAPESPMALLADPAPAADPGPEDI
GPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQF-----
-QNFLPTVVHP-GDLQTH-----LAVQTKRVAAQVDGGAQVQQVLNIEC-----------
LRDF---LTPPLLSVRFRYG--GTAQSL---TLKLPVTINKFFQPTEMAAQDFFQRWKQL
SL-PLQEAQKIFKANHPMDAEVT----KAKLLGFGSALLD-NVDPNPENFVGAG------
------------IIQ-TKALQV-GCLLRLEPNAQ--------------------------
--------------AQMYRLTLRTSKEPVS-----------RHLCELLAQQF--------
-----------------
>gi|50308487|ref|XP_454245.1|	Kluyveromyces lactis
------------------------------------------------------------
------------------------------------------------------MGSLRT
FIKEVRA-------------------------------AKTLAEERSIVTKESARIRTKL
KDDH-ISLERRRKYINKLLYLYILGEKTHFAQVECINLIASE--DFADKRVGYLAAVLLL
DENQELLTLLTNLLNN-----------DLNHPSRYVVSLAINALGALTSPELARDLYTDI
KNILEH-SRDSFLIKKALACSGKLIARDPSLLEI--F-APYANKMLSSKE------STSH
G---------------------------------------------------------VL
IGTNKLIQAII-----INTKSYEFDNLPE-----------IIDKLS---------SLIPD
LLGKLHHLNLGSSN--PEYNVGGCLDPFLQVELMTTLRLFLQYF----PE----------
------QT---KPYKNNYLDTLTRVATYTPTT--------SNSCTSVLYEAVRTIFSFQ-
-----------------------------AERSLRVLGVNVLGNLVADK-----------
---DYNTKYVSLNALLDVVSVE--PQAVQRHRKFISRCIF-DSDISIKKRALEMTFAILN
QTNMRELIAEILTFLEKAGEND--------------------KGLILYCVDQLIMVFDLQ
DE---IDDS--------WKLDVIVKILKFVGQYISVEKTTDALIMI--NNNS-NLEHK--
------KQVVSNIINVALDNDSSQVSDE-NLAWRVVSIWCIGEYADLIL------GN---
---GRCTETNLTGYLYESDSLYCDNPM-------VTSYVLLAALKLSVKIDTKVLSNRLR
QLIKGHT--ENTNVMIQTKAVQYGILFNES--TSVKAALLEPMPIFHKKVSETAALRTFS
Q-KVPAPAIKKVKKKEN-------------------------------------------
---------------------------------DLLLDLL--------------------
------------GDLS---------------------------TPETTAPTKPSN-----
--------DLLS-NL---------------------------------------------
------------------------------------------------------S-----
-NTPAPQSSNQNGSTLSS-------------------SFQQRIEIPPNS-----------
INIH----SSDIVEV---YGKVESSIPG---CTEIDLFLKAK---TNIN-----------
--------TLQILIAVPKSQKAE----------FGSLSSH-KVAT-----GEVA------
----------------KQGLKI-LGSGK-----I--------------------------
--------------KLRVKLNINSTEDQFD-----------YKFENIPH-----------
-----------------
>gi|45187937|ref|NP_984160.1|	Ashbya gossypii
------------------------------------------------------------
------------------------------------------------------MGSLRT
FIKDVRS-------------------------------AKTLADERSIITKESAKIRTKL
KDDH-LSLSKRRKNIHKLLYLYVLGEKTHFAQVECINLIASD--DFENKRLGYLAAMLLL
DEKQELLTLLTNVLNS-----------DLCHPTKYVVSLALCALGTLASVELARDLHPDV
ERILQT-SQDPYLFKKALQCAAKMVARDSFLASI--F-YPYVRRALSHEL-------STH
G---------------------------------------------------------VL
FGALQLLQSIM-----------AVEDLSD-----IDDQNKIVDAVA---------GAVPD
LLSKLQLLNTPSFT--PEYDAVGVADPFLQVELLYTLRRIFEKV----PD----------
------NV---SRYSGKLVSVLSSLCSHAEQS--------KNGTNAILYEAVRTIFALK-
-----------------------------LEHKLRIQAIDILAIFLTSK-----------
---DINNKYVALNMLTQVVSTE--PQAVQTRRKFISKCLF-DPDASIRRRALELTFAIIE
DSNMKDTVEELVAFLTSS---D--------------------GEDRDLIVYTVEHLLNIF
GMREVADER--------WKLTVLIRILKVIGQHMTVEIISEILVML--NNIS-DVATKKE
IGLQLVQFSLDKEQNNISEDNI---------GWKLIIVWVIGEYAELML------GE---
---PGVTDISLTNYLSSLNSFYSDDHK-------LIGYILTAALKLSLKIHDPACFERLR
QLIKSHD--RDTDLILQTKAVHYGILFSQP--ANIKKAFLEPMPLIVTTIR---------
--NSGPSATNATRKPSL----------------------------PDPIG----------
---------------------------------DLLSDIP--------------------
------------QTQS-----------------------------LPAVAVKSVN-----
TKQGDLLTDIFK------------------------------------------------
------------------------------------------------------S-----
-SSPPPVQKVPTPTATVT------------------VPAGATEMHHSNL-----------
VQVF-------GSVVSSANG-----------KAEVELFFKAKSRITQLH-----------
-----------VLVAVAKTQQLT----------LGALTNT-NMNP-----GDIT------
----------------CQSLQV-VGTGAL-------------------------------
--------------KLRVKLEASGGRNVAI------------------------------
-----------------
>gi|115720191|ref|XP_792773.2|	Strongylocentrotus purpuratus
MPAPIRLKDLIRNIRAVRTAADERALVQKELAQIRAMFRDEDNTYRCRNVAKVLYIHMLG
YPAHFGQDRDRLSADVFEILEINQSDNTQCLFCKPLKKSCTAAAYMAMLSKMPAPIRLKD
LIRNIRA-------------------------------VRTAADERALVQKELAQIRAMF
RDE---DNTYRCRNVAKVLYIHMLGYPAHFGQLECLKLIASP--RYADKRIGYLGAMLLL
DERHDVHLLMTNSMKN-----------DMGHNTQYIVGLSLSCLGSICSPEMSRDLAGEV
EKMIKT--SNAYIRKKAVLCAVRIVRKVPELMEM--F-IPSVRSLLNDKN---------H
G---------------------------------------------------------VQ
LTAVVLITEMC-------------EKSHD-----------TLVHFK---------KLVPN
LVRILKNLVMSGYS--PEHDVSGVSDPFLQVKILRLLRIL--------GH----------
------HD---ADNSDAMNDILAQVATNTETS--------KNVGNAILYETVLCIMDIK-
-----------------------------SESGLRVLAINILGRFLLNT-----------
---DKNIRYVALNTLLKTVQAD--NNAVQRHRSTIVDCLK-DPDVSIQRRAVELSFALIN
TSNIRTMVKELIFFLDRS---D--------------------PEFKSYTSSNIFLACERY
SP----NKR--------WHIDTMMRVLSTAGNNVPDESVASLIQMI--SDTS-SLH----
------AYTVQQLYKAVK-DDI---SQQ---PLAQVSAWCVGEYGDLLVQGVVDEEE---
---PI--QVSEDDVLDLLESMIQTTTSSQI----TKEYILLAILKLSVRFSETNER--IE
KIVKPYT--RSLDMELQQRSVEFMSLTKSY--KHIAGPLLERMPPMNREKR---------
--EGQTQNNGEMLEDEQ----------------------------VDRTGPSLAPSH---
---------DEG---------------------SSLVDLL--------------------
------------GGGP-----------------SSPIITNSLPQQQPAKPLEPVG-----
-NNTDGLLDLLG-GLDLSAPAPSSAPPPVQPT----------------------------
------------------------------------PNPVMNLMDGLGSMQTVPP-----
-PGSVPPALGM-NSLLGG-------------------PVNNIGGSSFPT-----------
VTAV----ESRGMKVEFSFE--KDAVSG---AVNINLKATNSTA-TPFN-----------
--------AFLFQAAIPKTFELV-------------MLPP-SGDLVPPNNSGFV------
----------------TQTIKV-VN--RSPGAVL--------------------------
--------------RMKYKLSFSIDGVPVSDT---------GEAANMPTNLFT-------
-----------------
>gi|119572921|gb|EAW52536.1|	Homo sapiens
------------------------------------------------------------
---------------------------------------------MPAVSKGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYTEKQIGYLFISVLV
NSNSELIRLINNAIKN-----------DLASRNPTFMCLALHCIANVGSREMGEAFAADI
PRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEW-TARVVHLLNDQH---------M
G---------------------------------------------------------VV
TAAVSLITCLC-------------KKNPD--------------DFK---------TCVSL
AVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCY-P------PP----------
------ED---AAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYD-
-----------------------------SEPNLLVRACNQLGQFLQHR-----------
---ETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCD
RSNAKQIVSEMLRYLETA---D--------------------YAIREEIVLKVAILAEKY
AV----DYS--------WYVDTILNLIRIAGDYVSEEVWYRVLQIV--TNRD-DVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---PR--SSPPVQFSLLHSKFHLCSVA-------TRALLLSTYIKFINLFPETKAT--IQ
GVLRAGSQLRNADVELQQRAVEYLTLSSVA-STDVLATVLEEMPPFPERESSILAKLKRK
KGPGAGSALDDGRRDPS----------------------------SNDINGGMEPTP---
------STVSTP---------------------SPSADLL--------------------
------------GLRA---------------------------APPPAAPPASAG-----
--AGNLLVDVF--DGPAAQPSLGPTPEEAFLS----------------------PGPEDI
GPPIPEADELLNKFVCKNNGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQF-----
-QNFSPTVVHP-GDLQTH-----LAVQTKRVAAQVDGGAQVQQVLNIEC-----------
LRDF---LTPPLLSVRFRYG--GAPQAL---TLKLPVTINKFFQPTEMAAQDFFQRWKQL
SL-PQQEAQKIFKANHPMDAEVT----KAKLLGFGSALLD-NVDPNPRRHQGLGDAWDFP
PAFCIFIFVHLLLFT-FWGVRG-SPPPSLSPPST--------------------------
--------------EGRGAREVDVSSPPTPPCCSPSYPLPIQGLCIIVSE----------
-----------------
>gi|121714353|ref|XP_001274787.	Aspergillus clavatus
------------------------------------------------------------
---------------------------------------------------MSSMRGLVQ
FIADLRN-------------------------------ARARELEEKRVNKELANIRQKF
KAGN-LNGYQKKKYVCKLLYMYIQGYEVDFGHLEAVNLVSST--KYSEKQIGYLAVTLFL
HEQHELLHLVVNSIRK-----------DLLDHNELNNCLALHAVANVGGREMGEALSMDV
HRLLISPTSKAFVKKKAALTLLRLYRKHPGIVQN-EW-AERMISLMDDPD---------M
G---------------------------------------------------------VT
LSVTSLIMALA-------------QDRPD--------------EYK---------GSYIK
AAQRLKRIVVDNEVA-PDYLYYRVPCPWIQVKMLRLLQYY-P------PS----------
------ED---SHVREIIRASLQQIMTTAMDTAKN--VQQNNAQNAILFEAINLLIHLD-
-----------------------------TEHNLMVQISARLGKYIQSR-----------
---ETNVRYLGLEAMTHFAARAETLDPIKKHQNIILGSLR-DRDISVRRKGLDLIYSMCD
TTNAAPIVNELLRYLQTA---D--------------------YAIREEMVLKVAILTEKY
AA----DAQ--------WYIDMTLKLLSLAGDHVNEEVWQRVIQIV--TNNE-ELQ----
------AYAAHTLLGYLK-TD----CHE---SLVKIGCYVLGEFGHLIA------DN---
---EG--SSPIEQFMALQGKMVTSNDN-------TRAMILSSFVKFVNLFPEIKPQ--LL
HIFRLYS--HSPDTELQQRAFEYLTLATLP-TDDLLRTVCDEMPPFSERASILLSRLHQK
T-AGTTEKKTWVVGGKD----------------------------ANADKK---------
-----------E---------------------VLMAQHT--------------------
------------GLKR------------------------TFTTIVNGTKTGANG----A
AAASNASGDLAGLDLSAPPAAAPNMASAAHLS----------------------------
----PDWEPGYNRLYFSDEGVLFEDAQIQVGLRSEFRGHMGVVKIYISNKSSYPI-----
-ASLTTTLDNP-AAPNLK-----IDSKNLP-ETSVAAAGQTQQTLFFGA-----------
HGPF---ADAPTIRISYLAG---ALQAY---TLQLPVLMHRYMEPSTLSAEEFFKRWRQI
GG-APLEAQRTF-GVTGKVKNVTEAFTRRVVESFHWKILD-NVDPNPHNIVGCA------
------------VYQ-FQGGKT-GCLLRLEPNYE--------------------------
--------------RKMYRVTIRATQEAVP-----------QALTKQMEQKLAQGATDMY
GLR--------------
>gi|156552529|ref|XP_001599424.	Nasonia vitripennis
------------------------------------------------------------
---------MWPYYETDDWSILPPELNRRFNPAFNMASIKQAFNEAVERVRMPAPTRLRD
LIRQIRA-------------------------------ARTAAEERTVVNKECAYIRSTF
REE---DSVWRCRNIAKLLYIHMLGYPAHFGQLECLKLIASP--RFTDKRIGYLGAMLLL
DERQDVHLLITNCLKN-----------DLNSSTQFVIGLALCTLGAIASPEMARDLASEV
ERLMKS--PNAYIRKKAALCAFRIIRRVPELMEM--F-LPATRSLLTEKN---------H
G---------------------------------------------------------VL
ITGVTLITEMC-------------ENSVD-----------TLNHFKKEC---GHREIVPN
LVRILKNLILAGYS--PEHDVSGVSDPFLQVKILRLLRIL--------GR----------
------ND---VDASEAMNDILAQVATNTETS--------KNVGNTILYETVLSIMDIK-
-----------------------------SESGLRVLAVNILGRFLLNN-----------
---DKNIRYVALNTLLKTVFVD--TSAVQRHRATILECLK-DPDVSIRRRAMELSFALID
TNNIRNMMKELLIFLERA---D--------------------PEFKAQCSSNIVMSAERF
AP----GKR--------WHLETLFKVLVAAGNYVRDDVVACTIQLI--SETE-SQQ----
------VYAVSALWRALE-KDTY--DKQ---PLTQVATWCIGEYGDLLLYGPHPEDS---
---DA---PVNDEVIDVYQRLLWSPQNTVV----TKQYTLLSLTKLSTRFQRGNEK--IR
QIIDTFG--SNLHIELQQRGIEFSQLFRKY--DHLRPSLLERMPAMETAR----------
--PQANGIIGVVNGDPE---------------------------VEEEKPQVIEPVN---
-----ATPPSDS---------------------SALLDLL--------------------
------------GSSD-------------------LNSPISTAPVNNLSAATTPV-----
-TNNNDLLDLLG-GLDLSTASAPTIP----------------------------------
-------------------------------------------------QQQSPQ-----
-QIFSPTNTS--NYLVDG-----LLNS---------SSMPIQNAPEIPS-----------
MVVF----DKQGLKITFKLE-RSLDNPD---LLVINMVAQNSGM-SPIT-----------
--------DFLFQAAVPKTFQLN-------------MLSP-SGTALP--PSGQV------
----------------TQVLKV-TNINK---AAL--------------------------
--------------RMRLRISYTGTAGPVLEQ---------AEVNNFPTTTVQ-------
-----------------
>gi|150864485|ref|XP_001383321.	Pichia stipitis
------------------------------------------------------------
------------------------------------------------------MASLKS
FIKAVRK-------------------------------AKTIADERAVVRKESAAIRTSF
RDVT-LDQTTRRINISKLLYLYIMGEKTHFGQVECLKLLASP--RFVDKRLGYLAASLLL
DENQEVLTLLTNSLDN-----------DMQHPNAYIVGLALCCLGNIASPELARDLYQNV
EKIIAS--NNVYLKKKACIVAAKLVEKEPDLFEF--F-LPKIGQLLSDKS---------P
A---------------------------------------------------------VL
LGALRLTNSLY-------------LASED-----------THPVLV---------KNIPK
IISHLKRVNTSGYQ--PDYDVMGTADPFLQVALLSTLRTL--------AT----------
------DEYCPDQHLEEINDILTQVASNLDSG--------KNAAHAILYECVRTIFAIQ-
-----------------------------SDQSLKILGVNLLGKFLSTK-----------
---ENNTRYVALDSLLSVISIE--PLAVQRHRSTIVNCLS-DGDISIRRRALELSFAILN
EQNIRVLVREILTFLENC--ND--------------------NELKPYVTSQLTIAANKY
SP----NEK--------WHFDTLIRMLKLSGDYVTSDNISSILALILQCNDN-ELK----
------KHIVQKLLTSCL-EDS---TQF---GLSLITVWSLGEYADLVL-GTNVEVH---
---SKEILVTDKVVLDLIDNLINNSTYSESETVQLITYILTAVIKLSVKFSDGASLEHLR
QILNART--YDNNLEIQVRAVEYQEIFAQD--VSLKRGLLARMPAPPVKER---------
----------ESLTLQK----------------------------ANNKAKRVGSSPNSG
------VPSTTE---------------------DLLLDLM--------------------
------------DDNG------------------------------DSNGVNGNK-----
-DATALLSDIFG------------------------------------------------
-----------------------------------------------GSNGTVS------
----ASQNNNA-AILDLF--------------NTSPAAPAAPIAEETNS-----------
IPAF----SNNFIKVSFVPK--SFPSNG---EAIIEALVDSNSA-STVE-----------
--------QFQFLIAVPKTQKLTI---------SSSSEGD-TLVP-----GGRI------
----------------KQVLKL-AGKQG---SKV--------------------------
--------------KFRVKAKYTVNGNAI------------EEQFDFGAFSQTL------
-----------------
>gi|157106242|ref|XP_001649235.	Aedes aegypti
------------------------------------------------------------
----------------------------------------------MAPVRGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGQMEAVNLLSSN--KYSEKQIGYLFISVLV
NTNSDLIKLIIQSIKN-----------DLQSRNPIHVNLALQCIANIGSRDMAEAFSTEI
PKLLVSGDTMDVVKQSAALCLLRLYRTCPDIIPGGEW-TTRIIHLLNDQH---------M
G---------------------------------------------------------VV
TAATSLIDALV-------------KKNPD--------------EYK---------GCVSL
AVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNP------PT----------
------ED---PGVRGRLNECLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHND-
-----------------------------SEANLLVRACNQLGQFLSNR-----------
---ETNLRYLALESMCHLATSEFSHEAVKKHQEVVILSMKMEKDVSVRQQAVDLLYAMCD
RTNAEEIVQEMLNYLETA---D--------------------YSIREEMVLKVAILAEKY
AT----DFT--------WYVDVILNLIRIAGDYVSEEVWYRVIQIV--INRE-EVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---SR--SAPMVQFKLLHSKYHLCSSM-------TRALLLSTYIKFINLFPEIRST--IQ
DVFRQHSNLRSADAELQQRASEYLQLSIVA-STDVLATVLEEMPSFPERESSILAVLKKK
K-PGRVPENAEIRDNKS----------------------------PVPNAHNAHAAQTN-
-----HTVSINS---------------------TASSDLL--------------------
------------GLST---------------------------PPANQSQTGT-------
------LIDVLG-DIYSATNGTGNVINNA-------------------------------
-----------KKFVFKNNGVLFENDLLQIGVKSEFRQNLGRLGLYYGNKTQTAL-----
-QNFVPTLQWS-PEDALK-----LNVQIKAVEPTLEAGAQIQQLLTAEC-----------
IDNY---SEAPSIVISFRVS-GGAPQKI---TVLLPLTINKFFEPTEMNAESFFARWKNL
GG-EQQRAQRVFKAQQPLDLPGA----RNKLMGFGMQLLD-SVDPNPDNMVCAG------
------------IIH-TQAHKV-GCLLRLEPNKQ--------------------------
--------------AQMFRLTIRSSLENVT-----------QEICNLLVDQF--------
-----------------
>gi|109461875|ref|XP_001078324.	Rattus norvegicus
------------------------------------------------------------
---------------------------------------------MPAVSKGDGMRGLAV
FISDIRN-------------------------------CKSKEAEIKRINKELANIRSKF
KGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--KYTEKQIGYLFISVLV
NSNSELIRLINNAIKN-----------DLASRNPTFMCLALHCIANVGSREMGEAFAADI
PRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEW-TARVVHLLNDQH---------M
G---------------------------------------------------------VV
TAAVSLITCLC-------------KKNPD--------------DFK---------TCVSL
AVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCY-P------PP----------
------ED---AAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHYD-
-----------------------------SEPNLLVRACNQLGQFLQHR-----------
---ETNLRYLALESMCTLASSEFSHEAVKTHIDTVINALKTERDVSVRQRAADLLYAMCD
RSNAKQIVSEMLRYLETA---D--------------------YAIREEIVLKVAILAEKY
AV----DYS--------WYVDTILNLIRIAGDYVSEEVWYRVLQIV--TNRD-DVQ----
------GYAAKTVFEALQ-APA---CHE---NMVKVGGYILGEFGNLIA------GD---
---PR--SSPPVQFSLLHSKFHLCSVA-------TRALLLSTYIKFINLFPETKAT--IQ
GVLRAGSQLRNADVELQQRAVEYLTLSSVA-STDVLATVLEEMPPFPERESSILAKLKRK
KGPGAASALDDSRRDTS----------------------------SNDINGGVEPTP---
------SNVSTP---------------------SPSADLL--------------------
------------GLRA---------------------------APPPAAPPAPVG-----
---GNLLVDVFS-DGPTAQPSLGPTPEEAFLSELEPPAPESPMTLLADPAPAADPGPEDI
GPPIPEADELLNKFVCKNSGVLFENQLLQIGVKSEFRQNLGRMYLFYGNKTSVQF-----
-QSFLPTVVHP-GDLQTHILCSCLAVQTKRVAAQVDGGAQVQQVLNIEC-----------
LRDF---LTPPLLSVRFRYG--GTAQSL---TLKLPVTINKFFQPTEMAAQDFFQRWKQL
SL-PLQEAQKIFKANHPMDAEVT----KAKLLGFGSALLD-NVDPNPENFVGAG------
------------IIQ-TKALQV-GCLLRLEPNAQ--------------------------
--------------AQMYRLTLRTSKEPVS-----------RHLCELLAQQF--------
-----------------
>gi|45552125|ref|NP_788891.2|	Drosophila melanogaster
------------------------------------------------------------
---------MYPYYE-QDWSVLPPENNRRFNPAFNMATIRQAFTEAVERVRMPTPTRLRD
LIRQIRA-------------------------------ARTAAEERAVVNKECAYIRSTF
REE---DSVWRCRNIAKLLYIHMLGYPAHFGQLECLKLTAST--RFTDKRIGYLGAMLLL
DERQDVHLLITNCLKN-----------DLNSSTQFVVGLALCTLGAIASPEMARDLASEV
ERLMKS--PNTYIRKKATLCAFRVIRRVPELMEI--F-LPATRSLLSEKN---------H
G---------------------------------------------------------IL
ITGVTLITEMC-------------ENSSD-----------TLMHFKKDS---GNREIVPN
LVRILKNLILGGYS--PEHDVSGVSDPFLQVKILRLLRIL--------GH----------
------ND---PDASEAMNDILAQVATNTETS--------KNVGNTILYETVLSIMDIR-
-----------------------------SEGGLRVLAVNILGRFLLNS-----------
---DKNIRYVALNTLLRTVHAD--TSAVQRHRTTILECLK-DPDVSIRRRAMELSFALIN
AQNIRTMTKELLLFLEKA---D--------------------AEFKAQCSSGMILAAERY
SP----TTR--------WHLDTQLSVLIAAGNYVRDDVVSSTIQLV--SSSPVPEQ----
------TYITNRFWESLQVANH---CED-KQPLLQVAVWAIGEYGDLFMYGANEDEF---
---ER---PTESDLIAVYYKFLTSAQVSTT----SKQYALVSLAKLSTRLQQCVEE--IQ
ALITSFG--SHLNVDLQQRGVEFTQLFGHY--KHLRPPLLEKMPAMQISRIS--------
--SQNGESGGGSFDDNS----------------------------PDVIENGVEGGGGGG
HSLIESNMNTLG------------------DNTNILLDLL--------------------
------------GSTDLSAGG-----------AGDLVAATDLSNAVHKKNSRNANDVVAP
VSNNQDLLDLLDLDLSAPSSTTTGAPAGGGGG------------------------GGIV
ALVGDNNQSSAANMNNMLGGLDLGGFGSGLDSSASIPTNGNDLASMLGGLGAPPA-----
-ASPSLAASAPVGNLIDG-----HAGSLLADLNPTAASNNVVVPPQGPR-----------
LTAL----DKDGLLVQLVSV-RGSD------CMRIYMTTTNNSD-NTLD-----------
--------QYLLQAAVQRSFQLQ-------------MLTPSGSVLPP---GGVI------
----------------TQEMRV-VATSN---ATL--------------------------
--------------RMRLRIQYVLDGQQQVEQ---------TEVSGFPEQQPAPAAAE--
-----------------
>gi|73983473|ref|XP_533200.2|	Canis familiaris
------------------------------------------------------------
----MDAGCHRQLMVQLCHQPSPLALPLRGAELGQGEKEEQPRRRGARTPPRPATAGLTF
MSRRPAGPPSRAAGRRSRAPPEVPPQDAGAPPPRTALWGKSKEAEIKRINKELANIRSKF
KGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSN--RYTEKQIGYLFISVLV
NSNSELIRLINNAIKN-----------DLASRNPTFMGLALHCIANVGSREMAEAFAGEI
PKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDW-TSRVVHLLNDQH---------L
G---------------------------------------------------------VV
TAATSLITTLA-------------QKNPE--------------EFK---------TSVSL
AVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCY--------PP----------
------PD---PAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHD-
-----------------------------SEPNLLVRACNQLGQFLQHR-----------
---ETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCD
RSNAQQIVAEMLSYLETA---D--------------------YSIREEIVLKVAILAEKY
AV----DYT--------WYVDTILNLIRIAGDYVSEEVWYRVIQIV--INRD-DVQ----
------GYAAKTVFEALQ-APA---CHE---NLVKVGGYILGEFGNLIA------GD---
---PR--SSPLIQFNLLHSKFHLCSVP-------TRALLLSTYIKFVNLFPEVKTT--IQ
DVLRSDSQLKNADVELQQRAVEYLRLSTVA-STDILATVLEEMPPFPERESSILAKLKKK
KGPNTVTDLEDAKRERS-----------------------------ADVNGGPEPAP---
-----ASAASTP---------------------SPSADLL--------------------
------------GLGA-----------------------------APPAPVGPPP-----
-SSGGLLVDVFS-DSPSAVAPLAPGSEDNF------------------------------
-----------ARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQF-----
-LNFTPTLICS-DDLQTN-----LSLQTKPVDPTVDGGAQVQQVVNIEC-----------
VSDF---TEAPVLNIQFRYG--GTFQNV---SVKLPITLNKFFQPTEMASQDFFQRWKQL
SS-PQQEVQNIFKAKHPMDTEIT----KAKIIGFGSALLE-DVDPNPANFVGAG------
------------IIH-TKTTQI-GCLLRLEPNLQ--------------------------
--------------AQMYRLTLRTSKETVS-----------QRLCELLSEQF--------
-----------------
>gi|70982175|ref|XP_746616.1|	Aspergillus fumigatus
------------------------------------------------------------
---------------------------------------------------MSSMRGLVQ
FIADLRN-------------------------------ARARELEEKRVNKELANIRQKF
KAGN-LNGYQKKKYVCKLLYVYIQGYDVDFGHLEAVNLISSN--KYSEKQIGYLAVTLFL
HEQHELLHLVVNSIRK-----------DLLDNNELFNCLALHAVANVGGREMGEALSTDV
HRLLISPTSKAFVKKKAALTLLRLYRKYPGIVQN-EW-AERMISLMDDPD---------M
G---------------------------------------------------------VT
LSVTSLIMALA-------------QDRPE--------------EYK---------GSYIK
AAQRLKRIVVDNEIA-PDYLYYRVPCPWIQVKLLRLLQYY-P------PS----------
------QD---SHVREIIRASLQQIMTTAMDTPKN--VQQNNAQNAILFEAINLLIHLD-
-----------------------------TEHNLMMQISSRLGKYIQSR-----------
---ETNVRYLGLEAMTHFAARAETLDPIKKHQNIILGSLR-DRDISVRRKGLDLIYSMCD
TTNAAPIVNELLRYLQTA---D--------------------YAIREEMVLKVAILTEKY
AT----DAQ--------WYIDITLKLLSLAGDHVNDEVWQRVIQIV--TNNE-ELQ----
------AYAAHTLLGYLK-TD----CHE---SLVKIGCYVLGEFGHLIA------DN---
---EG--SSPIEQFLALQGKMITSNDN-------TRAMILSSFIKFVNLFPEIKPQ--LL
HIFRLYS--HSPDTELQQRAFEYLTLATLP-TDDLLRTVCDEMPPFSERTSILLSRLHQK
T-AGTTEKKTWVVGGKD----------------------------ANADKK---------
-----------E---------------------VLLAQNT--------------------
------------GLKR------------------------TFTTIVNGTKTGANG----S
AATSNASGDLAGLDLSAPPAPPPNMASAAHLT----------------------------
----PDWEPGYNRLYFADEGVLFEDAQIQVGLRSEYRGHMGVVKIYISNKSSFAI-----
-GSLTTTLDNP-AAPNLK-----IDSKSLP-EPSVPAAGQTQQTLLVEA-----------
HGPF---SDAPTIRISYLAG---ALQAY---TLQLPVLMHRYMEPSTLSAEEFFKRWRQI
GG-PPLEAQHTF-GVTAKAKNVSETFTRRLVEGFHWRILE-NVDPNPNNIVGCA------
------------VYQ-SHGGKT-GCLLRLEPNYE--------------------------
--------------RKMFRVTIRATQEAVP-----------QALAKQMEQKLAQGAPDEM
FGSR-------------
