>gi|126290144|ref|XP_001366530.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
------------MSGPRAPNERPTGPGGVKRGRL-----------------------QQE
ATAVGSRVTVVLGAQ--W----GDEGK----GKVVDLLATDADVIC---RC--QGGNNAG
HTVVV-----DGKEF-DFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKN-EKKG--L
KDWEKRLIISDRAHI-----------------------VFDFHQAVDGLQEMQR--QAQE
GKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEFSARFKNLAYQYQSMFPTLEV
DTDGQLKKLKVLAERIRPM--VQDGVYFIYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGIPPQNVGEVFGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEW
GVTTGRKRRCGWLDLMILRYAHMINGFTALALTKLDILDALDEIKIGVSYK-LN-GKRI-
PYFPANQEILQKVEVEYETMPGWKTDTTGARKWEDLPPKAQNYIRFVENHI-GVA-----
----------------------VKWVGVGKSRESMIQLF---
>gi|83765970|dbj|BAE56113.1|	Aspergillus oryzae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MGVSIVLGSQ--W----GDEGK----GKITDMLAQQATLCC---RA--AGGHNAG
HTIVH-----GNKTY-DFHILPSGLISPSCINLIGAGTVVHVPSFFKELASL-EEKG--L
EGASKRIFISDRAHV-----------------------CLQLHSVVDGLEEAKL-----G
GRKVGTTGKGIGPCYSDKASRRGIRVGEILDE-----AVFERKLRSLDAGYRARFGDLEY
NVEEELAQFKEYRKLLGPY--IVDQLAFLQK-YKD--SPNTLVEGANALMLDLDHGTYPY
VTSSSTGLGGAMQALSLNPTSIKSVIGVVKAYTTRVGSGPFPSEQFNADGDKLQSVGREF
GVTTGRRRRCGWLDLVVCRYSQAINHYTALNLTKLDVLDDFDEIKVGVAYILPD-GTRTE
NTIPADAEVLEKVKVEYVTLPGWKSNTMGVKKYEDLPDNARAYIEYIERELGGVP-----
----------------------VKWIGTGPARDDMIARE---
>gi|70996316|ref|XP_752913.1|	Aspergillus fumigatus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MGITIVLGSQ--W----GDEGK----GKITDMLSQQATLCC---RA--AGGHNAG
HTIVH-----ENITY-DFHILPSGLVSPSCVNLIGAGTVVHVPSFFKELASL-EEKG--L
KDAGKRIFISDRAHV-----------------------CFDLHSIVDGLEEAKL-----G
GRKVGTTGKGIGPCYSDKAARRGVRIGEVLDE-----AVFERKLRSLHAGYTARFGELQY
DVEEEIGRFKDYRKRLVPY--IVDQLAFFKQ-YKD--SPNTLVEGANALMLDLDHGTYPY
VTSSSTGLGGAVQALSLNPTSITSVIGVVKAYTTRVGSGPFPSEQLNEYGDKLQSVGREF
GVTTGRRRRCGWFDLVLCRYSQAINHYTALNLTKLDILDDFDEIKVAVAYVLPD-GTRLT
DTYPADPEVLEKVKVEYVTLPGWKSNTMGVKKYEDLPANARAYIEYIERELGGVP-----
----------------------IKWIGTGPARDHMICRE---
>gi|126139071|ref|XP_001386058.	Pichia stipitis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MCDVVLGSQ--W----GDEGK----GKLVDLLCDDIDVCA---RC--QGGNNAG
HTIVV-----GDVKY-DFHMLPSGLVNPNCLNLVGSGVVVHVPSFFQELENL-EKKG--L
NCRD-RLFLSSRAHL-----------------------VFDFHQRTDKLKEAEL---SEN
KKAIGTTGKGIGPTYSTKASRSGIRVHHLVSEDPEAWEEFKTRYHRLVNSRKQRYGEFDY
DVEEELARYEKYRELLRPF--VVDSIEFMHTALVQ--NKRILVEGANALMLDIDFGTYPY
VTSSSTGIGGVLTGLGIPPKTINNIYGVVKAYTTRVGEGPFPTEQLNEFGEALQTIGAEY
GVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDSFKEIQVGVGYK-LN-GKSL-
ASFPEDLIKLGKVEVEYKTLPGWETDITKIKTYDELPENAKSYLKFIEDYL-GVP-----
----------------------VQWVGTGPARDSMLEKPISK
>gi|147905716|ref|NP_001080088.	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
-------------------MSAENESPGLPNGGA------------------CCASATGH
FLLVGNKVTVVLGAQ--W----GDEGK----GKVVDLLAQDADIVC---RC--QGGNNAG
HTVVV-----DSVEY-DFHLLPSGIINQNAIAFIGNGVVIHLPGLFEEAEKN-LKKGQGL
AGWEKRLCISDRAHI-----------------------VFDFHQAADGIQEQQR--QEQA
GKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FNEFSQRFKLLAKQYKSMYPSLEI
DIDGELKKLQDYADRVKPM--VKDGVYYIYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGIPPQSIGDVYGVVKAYTTRVGIGAFPTEQNNDIGEMLQTRGHEY
GVTTGRKRRCGWLDLVLLRYAHMINGFTALALTKLDILDVFSEIKVGVSYK-ID-GKNI-
PHFPANQEVLNKVEVEYETLPGWNKDTSNVRTFEELPENAKKYVQFIKEEL-GIP-----
----------------------IKWIGVGKSRESMIQLF---
>gi|6685827|sp|Q9Y0Y2|PURA_DROM	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
--------------------MSASATNGTHYEQL----------------------HQGR
TKMYKSKVDVVLGAQ--W----GDEGK----GKVVDMLASDVDIVC---RC--QGGNNAG
HTVVA-----NGTEF-DFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVLKN-EAKG--L
QHLENRLIISDRAHL-----------------------VFDFHQHVDGMQEAEK-----G
GKSLGTTKKGIGPAYSSKATRNGIRVGELLGD----FNLFSEKFKSIVATHVRLFPSINV
DVEAELARYKDYADKVRPY--VKDTICFLHTALRN--GKTILVEGANAAMLDIDFGTYPY
VTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPTEQLNDIGDLLQTRGFEV
GVTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTKLDILDTLPEIKVAVAYKKPN-GEKL-
DHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKELPENAQSYVRLLESEL-SVP-----
----------------------VRWVGVGKGRESIINVH---
>gi|6324109|ref|NP_014179.1|	Saccharomyces cerevisiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVNVVLGSQ--W----GDEGK----GKLVDLLVGKYDIVA---RC--AGGNNAG
HTIVV-----DGVKY-DFHMLPSGLVNPNCQNLLGNGVVIHVPSFFKELETL-EAKG--L
KNARSRLFVSSRAHL-----------------------VFDFHQVTDKLRELELSGRSKD
GKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEFVARYKRLLETRRQRYGDFEY
DFEAKLAEYKKLREQLKPF--VVDSVVFMHNAIEA--KKKILVEGANALMLDIDFGTYPY
VTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTTRVGEGPFPTEQLNENGEKLQTIGAEF
GVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGISYS-IQ-GKKL-
DLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDLPENAKKYLKYIEDFV-GVP-----
----------------------VEWVGTGPARESMLHKEIK-
>gi|149737753|ref|XP_001492555.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
------------MSGTRASNDRPPGAGGVKRGRL-----------------------QQE
AAATGSRVTVVLGAQ--W----GDEGK----GKVVDLLATDADIIS---RC--QGGNNAG
HTVVV-----DGKEY-DFHLLPSGIINTKAVSFIGNGVVVHLPGLFEEAEKN-EKKG--L
KDWEKRLVISDRAHL-----------------------VFDFHQAVDGLQEVQR--QAQE
GKNIGTTRKGIGPAYSSKAARTGLRVCDLLAD----FDEFSTRFKNLAHQHQSMFPTLEI
DVEGQLKKLKGFAERIRPM--VRDGVYFMYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGIPPQNVGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQSRGHEW
GVTTGRKRRCGWLDLMILRYAHMLNGFTALALTKLDILDALDEIKVGVSYK-LN-GKRI-
PYFPANQEMLQKVEVEYETLPGWKVDTTGARKWEDLPPQAQNYIRFVENHI-GVA-----
----------------------VKWVGVGKSRDSMIQLF---
>gi|121700891|ref|XP_001268710.	Aspergillus clavatus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MGITIVLGSQ--W----GDEGK----GKITDMLSQEATLCC---RA--AGGHNAG
HTIVH-----DNITY-DFHILPSGLVSPKCVNLIGAGTVVHVPSFFKELASL-EGKG--L
KGAGKRIFISDRAHV-----------------------CFDLHSVVDGLEEARL-----G
GRKVGTTGKGIGPCYSDKAARRGVRVGEIMDE-----AVFERKLRTLHAGYTARFGDLEY
DVEEEIGRFKEYRQRLVPY--IVDQLAFFKQ-YKD--SPNTLVEGANALMLDLDHGTYPY
VTSSSTGLGGAVQALSLNPASITSIIGVVKAYTTRVGSGPFPSEQLNEYGDKLQSVGREF
GVTTGRRRRCGWFDLVLCRYSHAINHYTALNLTKLDVLDDFDEIKVGVAYVLPD-GTRLT
DTYPADAAVQENVKVEYVTLPGWKSNTMGVQKYEDLPANARAYIEYIERELGGVP-----
----------------------VKWIGTGPARDHMICRE---
>gi|148686645|gb|EDL18592.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
----------ASMSGTRASNDRPPGTGGVKRGRL-----------------------QQE
AAATGSRVTVVLGAQ--W----GDEGK----GKVVDLLATDADIVS---RC--QGGNNAG
HTVVV-----DGKEY-DFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKN-EKKG--L
KDWEKRLIISDRAHLENEVPHKPLPSASLLPMCWLLAPVFDFHQAVDGLQEVQR--QAQE
GKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEFSARFKNLAHQHQSMFPTLEI
DVEGQLKRLKGFAERIRPM--VRDGVYFMYEALHGP-PKKVLVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEW
GVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISYK-LN-GKRI-
PYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHM-GVA-----
----------------------VKWVGVGKSRESMIQLF---
>gi|125774755|ref|XP_001358629.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
---------------------TTNAINGNLYEQL----------------------HQGR
TNMYKSKVDVVLGAQ--W----GDEGK----GKVVDMLASEVDIVC---RC--QGGNNAG
HTVVA-----NGTEF-DFHLLPSGVVNEKCISVIGNGVVIHLPSLFDEVLKN-EAKG--L
QHLEHRLIISDRAHL-----------------------VFDFHQHVDGMQEAEK-----G
GKSLGTTKKGIGPAYSSKATRNGIRVGELLGD----FNAFSDKFKLIVATHLRLFPSINV
DVEAELTRYRDYAEKVRPY--VKDTICFLHTALRN--GKTILVEGANAAMLDIDFGTYPY
VTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTTRVGDGPFPSEQLNEIGDLLQTRGFEV
GVTTKRKRRCGWLDIPLLRYTSLVNGYTCICLTKLDILDTLPEIKVAVSYKKAN-GDKL-
DHFPGTIAELGNIEVEYAVLPGWQTSTEHIRNFKELPENAQNYVRFLEKEL-SVP-----
----------------------VRWVGVGKGRESIINVH---
>gi|50307861|ref|XP_453924.1|	Kluyveromyces lactis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVNVVLGSQ--W----GDEGK----GKLVDLLVGEYDIVA---RS--AGGNNAG
HTIVV-----NGVKY-DFHMLPSGLVNPNCQNLIGNGVVIHVPSFFEELKSL-EAKG--L
KNAKGRLFISSRAHL-----------------------VFDFHQRTDKLRELELSGASKD
GKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDDPQAWEVFETRYRRLVETRQQRYGSFDY
DPEEELQRYKSYREQLKPF--VVDSVNFMHDAIKK--NKKILVEGANALMLDIDFGTYPY
VTSSNTGIGGVITGLGIPPRTIKEVFGVVKAYTTRVGEGPFPTEQLNEDGEKLQNIGAEF
GVTTGRKRRCGWLDLVVLKYSNLINGYTSLNITKLDVLDTFKEIKVGVSYS-VD-GKKL-
ESFPEDLLTLAKVEVEYVTLPGWEEDISKITNYEDLPENAQKYLKFIEDFV-EVP-----
----------------------IQWVGTGPARDAMVHKEI--
>gi|157018289|gb|EAA07403.4|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
---------------------SNHTAANNTHEQM----------------------HNRR
QNPYTQKVTVVLGAQ--W----GDEGK----GKVVDMLAADADIVC---RC--QGGNNAG
HTVVV-----NGVDF-DFHLLPSGIIHEKCISIIGNGVVVHLPGLFEELAKN-EAKG--L
KNWTDRLIISNRAHL-----------------------VLDLHQQVDGLQEAEK-----G
GKSLGTTKKGIGPCYSSKATRNGIRVSDLLGD----FKMFSEKFEALVAMYKRLYPDFSV
DVNAELARYREYAERLRPL--VRDSVSYLHTSLKE--GKSVLVEGANAAMLDIDFGTYPY
VTSSNCSIGGVLTGLGLPPQSIGEVIGVVKAYTTRVGDGPFPTELLDEIGSLLQKRGGEV
GVTTQRIRRCGWLDLPLLRYTSMVNGYTAICLTKLDILDTLKEIKVAVSYN-LN-GKKI-
DYFPGSITDLSQVEVNYVTVPGWLQCTENVRDFGELPPQAQDYIRFIESDL-DVP-----
----------------------VKWIGVGKGRESIICVKD--
>gi|108881348|gb|EAT45573.1|	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------MSKMMMNGSGTNGTAAVANNHK--------------------EMHQRC
LNPYRSKVTVVLGAQ--W----GDEGK----GKVVDMLATEADVVC---RC--QGGNNAG
HTVVV-----NGKDF-DFHLLPSGIINDKCTSIIGNGVVIHLPGLFDELAKN-EAKG--L
TNWESRLVISNRAHL-----------------------VFDLHQQVDGLQEAEK-----G
GKSLGTTKKGIGPCYSSKATRNGIRVSDLLGD----FKVFSEKFESLVNMYKRLFPNFEV
DVASELVRYRDYAERLRPL--VRDTVSLVHASLKE--GKSVLVEGANAAMLDIDFGTYPY
VTSSNCSIGGVLTGLGLPPQTIGEVVGVVKAYTTRVGDGPFPTELHDEIGSLLQKRGGEI
GVTTKRVRRCGWLDLALLRYTGMVNGYTSICLTKLDILDTLKEIKVAVSYT-LR-GEKI-
DYFPGSITDLAQVEVNYITMPGWLKSTENVRDFNELPPEAQDYIRMIENDL-GVP-----
----------------------VKWIGVGKGRESIINVKE--
>gi|73961442|ref|XP_537220.2|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
----------------MALAETDAAASSLPNGDC----------------------GRPG
ARPGGNRVTVVLGAQ--W----GDEGK----GKVVDLLAQDADIVC---RC--QGGNNAG
HTVVV-----DSVEY-DFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKN-VQKGKGL
RGWEKRLIISDRAHI-----------------------VFDFHQAADGIQEQQR--QEQA
GKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYKSIYPTLEI
DIEGELQKLKGYMERIKPM--VRDGVYFLYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREF
GVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LD-GEII-
PHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPINAQNYVRFIEDEL-QIP-----
----------------------VKWIGVGKSRESMIQLF---
>gi|45185044|ref|NP_982761.1|	Ashbya gossypii
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVNVVLGSQ--W----GDEGK----GKLVDLLVSKYDIVA---RS--AGGNNAG
HTICC-----GGNQVPTSHMLPLGLVNPYCQKLMDNGGVIHEPSFFGELEQL-EAKG--L
RDARGRLFISSRAHL-----------------------VFDFHQRTDKLRELELSGKSKD
GKNIGTTGKGIGPTYSTKASRSGLRVHHLVSEQPEAWAEFETKYRRLLETRQQRYGPFEH
DAEEELARYRRYREELRPF--VVDSVVFMHNAIQQ--KKKILVEGANALMLDIDFGTYPY
VTSSSTGIGGVLTGLGIPPRCIDEIYGVVKAYTTRVGEGPFPTEQLNEAGDKLQTIGAEY
GVTTGRKRRCGWLDLVVLKYSTLINGFTSLNITKLDVLDTFKEIKVGISYS-LN-GKKL-
DLFPEDLLVLSKVDVEYVTLPGWDEDITKISRYEDLPENAKSYLKFIEDFV-GVP-----
----------------------VEWVGTGPGRESMLHKEVS-
>gi|21619638|gb|AAH32039.1|	Homo sapiens
------------------------------------------------------------
----------------------------------------------------------GG
LVGRSCGVATQRQGGGQRPTNLALTLSSSPAHSTALPWLPPRSLQLLSGHSVPAQPTPHL
PSACGGPTRVTLGEERAWRSHGSNAGG----HTCLPRRTAGAGSLT---PGGERGGNNAG
HTVVV-----DGKEY-DFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKN-EKKG--L
KDWEKRLIISDRAHL-----------------------VFDFHQAVDGLQEVQR--QAQE
GKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEFSSRFKNLAHQHQSMFPTLEI
DIEGQLKRLKGFAERIRPM--VRDGVYFMYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGGLLQTRGHEW
GVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLGEVKVGVSYK-LN-GKRI-
PYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQNYIRFVENHV-GVA-----
----------------------VKWVGVGKSRESMIQLF---
>gi|109479984|ref|XP_001072867.	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
------------MSGTRASNDRPPGTGGVKRGRL-----------------------QQE
AAATGSRVTVVLGAQ--W----GDEGK----GKVVDLLATDADIVS---RC--QGGNNAG
HTVVV-----DGKEY-DFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKN-EKKG--L
KDWEKRLIISDRAHL-----------------------VFDFHQAVDGLQEVQR--QAQE
GKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEFSARFKNLAHQHQSMFPTLEI
DVEGQLKRLKGFAERIRPM--VRDGVYFMYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEW
GVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISYK-LN-GKRI-
PYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHL-GVA-----
----------------------VKWVGVGKSRESMIQLF---
>gi|66524128|ref|XP_392818.2|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
---------------MQRSVQQANGDSVLASPRK-----------------------KQR
VSNATTKVTVVLGAQ--W----GDEGK----GKVVDMLAMDADVVC---RC--QGGSNAG
HTVVV-----DGAEF-HFHLLPSGIINPRCTSVIGNGVVIHLPGLFEELESN-EAKG--L
KNWRERLIISDRAHI-----------------------VFDFHQQVDGLQELEK-----G
TQSLGTTKKGIGPTYSSKAARNGLRIGDLLGD----FDKFSQKFDTLVTSYQKMFPALQV
DIKAELQRYKEYAERIRPL--VKETVQYLHQALRE--GKKVLVEGANAAMLDIDFGTYPY
VTSSNCSIGGVCTGLGLPPSYIGEVVGVVKAYTTRVGDGPFPTELLNATGELLQRRGHEI
GVTTNRKRRCGWLDLTLLKFTAMVNGYTSICLTKLDILDTLPKIQVGVGYR-LN-GKEI-
DYFPSTTSDLVKVEVIYETLDGWQSTTEGVRSLEKLPPNAKKYIQLIEEHL-GVP-----
----------------------VKWIGVGAGRESVITL----
>gi|91094097|ref|XP_967036.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
----------------MASGVEVNGMNGSPRKRA----------------------RTAP
QAGHESKVIVILGAQ--W----GDEGK----GKVVDMLAETVDIVC---RC--QGGNNAG
HTVVI-----EGVEY-DFHLLPSGIIHPKCHSVIGNGVVIHLPGLFEEVEKN-EKKG--L
KDWESRLIISDRAHL-----------------------VFDFHQQVDGLQEQEN---TQK
GQGLGTTKKGIGPTYSSKATRNGIRIGELLGD-------FSQSIKS--------------
-------------------------------------GKKVLVEGANAAMLDIDFGTYPY
VTSSNCSVGGVCTGLGLSPNRIGEVIGVVKAYTTRVGDGPFPTELRDKIGDCLQERGAEV
GVTTKRKRRCGWLDVFLLQYTNIVNGYTALCLTKLDILDTLPEIKLGVGYK-LK-GKKI-
DYFPSSAAELAEVEVEYITLPGWKTSTENVRKFNDLPENAKKYVNKVEQLV-NVP-----
----------------------VKWIGVGKGRESIITLEE--
>gi|114573595|ref|XP_514311.2|	Pan troglodytes
MTREVERVGGVLKGKRSRSPAPDLFRSRGSHRSGAPGRGRGVASVRGGGRCRHQGLFLRA
VLPRPACAGQSWYPLERAVAESGAGTGWRVAARRGGGGAGLWLLLPLHVAGGRRAVQFAH
SSPAASPSGFPRVTGAMAFAETYPAASSLPNGDC----------------------GRSR
ARPGGNRVTVVLGAQ--W----GDEGK----GKVVDLLAQDADIVC---RC--QGGNNAG
HTVVV-----DSVEY-DFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKN-VRKG--K
EGWEKRLIISDRAHI-----------------------VFDFHQAADGIQEQQR--QEQA
GKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYKSIYPTLEI
DIEGELQKLKGYMEKIKPM--VRDGVYFLYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREF
GVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LD-GEII-
PHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDEL-QIPGKHKH
FMAFSL----------------YRFVGIDGYLKDKKK-----
>gi|149247068|ref|XP_001527959.	Lodderomyces elongisporus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MCDVVLGSQ--W----GDEGK----GKLVDILCDDIDVCA---RC--AGGNNAG
HTIVV-----DGKKF-DFHMLPSGLVNPKCQNLVGSGVVIHVPSFFEELKNI-EEKG--L
HCRD-RLKVSSRAHL-----------------------VFDFHQRTDKLKEAEL---SEN
KKSIGTTGKGIGPTYSTKASRSGIRVHHLVNSNPEAWNEFKTRYMRLVESRQKRYGEFDY
DYEAELAKYEKYREELRPF--VVDSVEFMHEAIAQ--KKKILVEGANALMLDIDFGTYPY
VTSSSTGIGGVLTGLGIPPKTIRNIYGVVKAYTTRVGEGPFPTEQLNSVGETLQDVGAEY
GVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDKFKEIQVGIAYK-LN-GKEL-
KSFPEDLIDLGNVEVVYKTLPGWEQDITKIKKYEDLPENAKNYLKYIEDFL-GVP-----
----------------------IQWVGTGPARDSMLEKKI--
>gi|89266856|emb|CAJ83843.1|	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
-------------------MSAENGSPGLPNGGV------------------CCATDSGR
CSLVGNKVTVVLGAQ--W----GDEGK----GKVVDLLAQDADIVC---RC--QGGNNAG
HTVVV-----DSVEY-DFHLLPSGIINQNAIAFIGNGVVIHLPGLFEEAEKN-LKKGQGL
VGWEKRLCISDRAHI-----------------------VFDFHQAADGIQEQQR--QEQA
GKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FSEFSQRFKLLAKQYKSMYPSLEI
DIDGELKKLQDYADRVKPM--VKDGVYYLYEALHGP-PKNILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGIPPQSVGDVYGVVKAYTTRVGIGAFPTEQNNDTGEMLQTRGHEY
GVTTGRKRRCGWLDLVLLRYAHMINGFTALALAKLDILDVLSEIKVGVSYK-ID-GKKI-
PHFPANQEVLNRVEVEYETLPGWNTDTCNVRTFEELPENAKKYVRYIELEL-GIP-----
----------------------IKWIGVGKSRESMIQLF---
>gi|115397651|ref|XP_001214417.	Aspergillus terreus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MGVTIVLGSQ--W----GDEGK----GKITDMLSQQATLCC---RA--AGGHNAG
HTIVH-----GSNTY-DFHILPSGLISPSCVNLIGAGTVVHVPSFFKELAAL-EEKG--L
QGASKRVFIADRAHV-----------------------CLDLHSVVDGLEEARL-----G
GRKVGTTGKGIGPCYSDKAARRGIRVGEILDE-----ALFERKLRNLESGYRARFGDLEY
NVEDEITRFKEYRKILGPH--IVDQLAFLQK-YKD--SPNTLVEGANALMLDLDHGTYPF
VTSSSTGLGGAVQALSLNPTSISSIIGVVKAYTTRVGSGPFPSEQLNEFGDKLQSVGREF
GVTTGRRRRCGWFDLVLCRYSQAINHYTALNLTKLDVLDDFDEIKVGVAYILPD-GTRTE
NTIPADAEVLDKVQVEYITLPGWKSNTMGVKKYEDLPANARAYIEYIERGLGGVP-----
----------------------VKWIGTGPARDDMICRE---
>gi|56759222|gb|AAW27751.1|	Schistosoma japonicum
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
NKGIERSVSVVLGAQ--W----GDEGK----GKLVDLLSESSTVVC---RC--QGGNNAG
HTVVA-----GGKEY-FFHLLPSGIINPNVLAIIGNGVVVNLEALFQEINEA-VNKG--L
LDVASRLRISDRCHL-----------------------VFPLHQEIDRMEEELR-----G
LNLLGTTKKGIGPAYSSKVTRNGLRVCDLIGD----WDQFTAKYKELVNYVKRRYPALEI
NVEESLEQLKTYREMLSGM--VCDSVLLINKLTESK-QTKILVEGAQSCMLDIDFGTYPH
VTSSNCSIGGVCTGLGLSPSRVGSVYGVIKAYTTRVGSGPFPTELLDGIGEYIQKKGNEW
GVTTKRMRRIGWLDTVVIRYAHIINDFNALALTKIDVLDGLKEVKIARAYVDPETGNEL-
SSFPADPFILSRVVVIYETLPGWKASTQNCRVYDELPPAAKTFIETVEKLL-NIP-----
----------------------IRWIGTGASRDSIIIRSV--
>gi|109019998|ref|XP_001102992.	Macaca mulatta
-----------MADRGAPEYAAAAQSEWRARPRKGRGRGRGVASARGGGGCRHQGLFLRA
VLPRPACAGQSWSPIERAVAESGAGTGWRVAARRGGGGASLWLLLPPHVAGGRRAVRFVH
SSAAASPSGSPRVTGAMALAKTYPATSSLPNGDC----------------------GRPR
ARPGGNRVTVVLGAQ--W----GDEGK----GKVVDLLAQDADIVC---RC--QGGNNAG
HTVVV-----DSVEY-DFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKN-VQKG--K
EGWEKRLIISDRAHI-----------------------VFDFHQAADGIQEQQR--QEQA
GKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYKSIYPTLEI
DIEGELQKLKGYMERIKPM--VRDGVYFLYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQENEIGELLQTRGREF
GVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LD-GEII-
PHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDEL-QIP-----
----------------------VKWIGVGKSRESMIQLF---
>gi|147899059|ref|NP_001090978.	Sus scrofa
------------------------------------------------------------
------------------------------------------------------------
------------MSGTRASNDRPPSAGGVKRGRL-----------------------QHE
AATTGSRVTVVLGAQ--W----GDEGK----GKVVDLLATDADIIS---RC--QGGNNAG
HTVVV-----DGKEY-DFHLLPSGIINTKAVSFIGNGVVVHLPGLFEEAEKN-EKKG--L
KDWEKRLIISDRAHL-----------------------VFDFHQAVDGLQEVQR--QAQE
GKNIGTTRKGIGPAYSSKAARAGLRVCDLLSD----FDEFSARFRNLARQHQSMFPTLET
DVEGQLKKLKGFAERIRPM--VRDGVYFMYEALHGP-PKKILVEGANAALLDIGFGTCPF
VTSSNCTVGGVCTGLGIPPQNIGEVYGVVKAYTTRVGVGAFPTEQINETGDLLQSRGHEW
GVTTGRKRRCGWLDLMILRYAHMINGFTALALTKLDILDTLDEVKVGVSYK-LS-GKRI-
PYFPANQEILQKVEVEYETLPGWKTDTTGARKWEDLPPQAQSYIRFVENHV-GVA-----
----------------------VKWVGVGKSRDSMIQLF---
>gi|58265156|ref|XP_569734.1|	Cryptococcus neoformans
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MAPSPEGVTVVLGAQ--W----GDEGK----GKLVDILAAEADICA---RC--AGGNNAG
HTIVVRNDKGEKTSY-AFNLLPSGLINPECTAFIGSGVVVHVPSLFNELDTL-ERKG--L
KVAG-RLFVSDRAHL-----------------------VMGFHQIVDGLKEVEL-----G
GSSIGTTRKGIGPAYSSKASRSGLRVHHLFDP------TFPAKFRKLVEGRFKRYGHFEF
DTEGEIEMYLAFAERLRPF--IVDGPTFMHNAVNS--GKRVLVEGANALMLDLDYGTYPF
VTSSSTSIGGVVSGLGISPFAIKRVVGVIKAYTTRVGGGPFPTEDLATVGETLQEVGAEY
GTVTGRRRRCGWLDLVVMKYSTMINGYTSLNLTKLDVLDGFDEIKVATGYK-ID-GVEV-
EGFPADLDRLAKVEVQYATLPGWKTDISNCKTYEEFPENAKAYIKFIEDYL-GVK-----
----------------------VQYVGVGPGRDQNVIIF---
>gi|149641661|ref|XP_001513692.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------MAGPEPLGQS--------------------QACQPF
SRGGTERSTLRGVCA--L----LAVDN----LLLVELELDPRAVLSVTGPT--AGGNNAG
HTVVV-----DSVEY-DFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKN-VQKGKGL
EGWEKRLIISDRAHI-----------------------VFDFHQAADGIQEQQR--QEQA
GKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGFSERFKVLANQYKSMYPTLEI
DIEGELHELKGYMERIKPM--VRDGVYFIYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGEKLQIRGREY
GVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDVFPEIEVGVAYK-LD-GEII-
PHFPANQEVLNKVEVQYQTLPGWNTDISNARTFEDLPVNAQNYVLFIEKEL-QIP-----
----------------------VKWIGVGKSRESMIQLF---
>gi|18032148|gb|AAL56637.1|AF12	Emericella nidulans
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----MAVTIVLGSQ--W----GDEGK----GKITDMLSQEATLCC---RA--AGGHNAG
HTIVH-----GNVTY-DFHILPSGLVSDKCINLIGAGTVVHVPSFFKELAAL-EAKG--L
KGAAARAFISDRAHV-----------------------CFDLHSVVDGLEEKGL-----G
GRKVGTTGKGIGPCYSDKASRRGVRVGEILDE-----EVFERKLRTLHAGYTARFGQLDY
DVEEEIARFKEYRKLLVPH--IVDQLAFFNK--HKD-SPNTLVEGANALLLDLDHGTYPF
VTSSSTGLGGAVQALHLNPTSIKSIIGVVKAYTTRVGSGPFPSEQLNEAGEKLQKVGREF
GVTTGRKRRCGWFDLVLLRYSQSINHYTALNLTKLDILDDFDEIKVAVAYTLPD-GTRLE
NTIPADAEVLNKVDVEYVTLPGWKSNTMGVKKYEDLPENARKYIEYIERELGGVP-----
----------------------VKWIGTGPARDDMICRE---
>gi|47219413|emb|CAG01576.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
----------------MASDGTVANVNGGEAGSL-----NGEPVVKRPRESGSQVSSLRV
PKEPHNKVTVVLGAQ--W----GDEGK----GKVVDLLAMDADIAC---RC--QGGNNAG
HTVVV-----DSVEY-DFHLLPSGVLNQKATSFIGNGVVIHLPGLFEEAEKN-LQKGEGL
QGWEERLKISDRAHI-----------------------VFNFHQAVDGIQEQQR--QQQE
GKNLGTTKKGIGPAYSSKAARNGLRICDLVGD----FKVFEEKFRMLAEHFQRMYQNLNI
NIDSDLEQLKGYAERLRPL--VTDGVYFMHKALTGP-SKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGVPPSHVGRVYGVVKAYTTRVGVGAFPTELTNETGDLLQSRGREF
GVTTGRRRRCGWLDLISVRYAHMVNGFSAIALTKLDILDTLPEIKVGVAYK-VD-GKPL-
PSFPANMDVLTRVSVEYETLPGWCCSTEAARSFEELPPQAQNYIRFIEDFL-QVPGGFKR
ACSPAVGAPAEAAPRLLSSLISVKWVGVGKSRESMIKLF---
>gi|156551281|ref|XP_001601167.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------MSACVRVQATNGDSANDTSSRK--------------------KLRVSG
QQQHQAKVTVVLGAQ--W----GDEGK----GKVVDMLASEADLVC---RC--QGGSNAG
HTVVV-----EGAEY-HFHLLPSGIINPRCKSVIGNGVVIHLPGLFEELEEN-EAQG--L
KDWQGRLIISDRAHI-----------------------VFDFHQQVDQLQELEK-----G
TRSLGTTKKGIGPAYASKAARTGIRIGELVGD----YDKFSEKFVALVASHQKIFPALKV
DVKAELERYRGYADRIRPY--VKETVHYLHHAAKD--GKKILVEGANAAMLDIDFGTYPY
VTSSNCSIGGVCTGLGLPPTVIGEIVAVVKAYTTRVGDGPFPTELLDATGEILQKRGCEF
GVTTKRKRRCGWLDLILLKYTAIVNGYTSICLTKLDILDTLPTIKVCTGYR-LN-GKEI-
DYFPSSTSDLAKVEPIYEEFEGWQTSTEGVRSFDNLPLSAQKYVQLLEEYL-DIP-----
----------------------VKWVGVGAGRESIIAI----
>gi|125848543|ref|XP_001342550.	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
----------MAADSTMSNGQETACLNGEPALKR----------------SRDSLDSLRV
PREPQNKVTVVLGAQ--W----GDEGK----GKVVDLLAMDADIVC---RC--QGGNNAG
HTVVV-----DSVEY-DFHLLPSGVLNKKATSFIGNGVVIHLPGLFDEAEKN-LQKGNGL
QGWEERLKISDRAHI-----------------------VFNFHQAVDGIQEQLR--QQQA
GKNLGTTKKGIGPAYSSKAARNGLRVCDLVSD----FSVFEEKFRVLAGHYQTTYPNLNI
DIDAELQQLKNFAERLRPL--VTDGVYFMHKALTGP-SKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGVPPSHVGRVYGVVKAYTTRVGVGAFPTEQNNEIGDLLQSRGREF
GVTTGRRRRCGWLDLVLVRYAHMVNGFSAIALTKLDILDTLPEIKIGTAYT-VD-GKPL-
PSFPANMDVLTKVQVTYETFPGWSCSTEGVRSFDELPTQAQSYIKFIEDFL-QVP-----
----------------------VKWVGVGKSRESMIKLF---
>gi|151944324|gb|EDN62602.1|	Saccharomyces cerevisiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVNVVLGSQ--W----GDEGK----GKLVDLLVGKYDIVA---RC--AGGNNAG
HTIVV-----NGVKY-DFHMLPSGLVNPNCQNLLGNGVVIHVPSFFKELETL-EAKG--L
KNARSRLFVSSRAHL-----------------------VFDFHQVTDKLRELELSGRSKD
GKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEFVARYKRLLETRRQRYGDFEY
DFEAKLAEYKKLREQLKPF--VVDSVVFMHNAIEA--KKKILVEGANALMLDIDFGTYPY
VTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTTRVGEGPFPTEQLNENGEKLQTIGAEF
GVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGISYS-IQ-GKKL-
DLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDLPENAKKYLKYIEDFV-GVP-----
----------------------VEWVGTGPARESMLHKEIK-
>gi|50292025|ref|XP_448445.1|	Candida glabrata
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------MVNVVLGSQ--W----GDEGK----GKLVDILVSHYDVVA---RC--AGGNNAG
HTIVV-----DGVKY-DFHMLPSGLVNPNCKNLLGNGVVIHIPSFFKELETL-ESKG--L
NDARGRLFISSRAHL-----------------------VFDFHQRTDKLRELELAGRSKD
GKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDNPGAWELFESRYRRLLETRKQRYGDFDY
DAEEELNRFKQYKESLKPF--VVDSVDFLHKSIAN--NEKILVEGANALMLDIDFGTYPY
VTSSNTGIGGVITGLGIPPQKIQEVYGVVKAYTTRVGEGPFPTEQLNEQGEKLQSIGAEF
GVTTGRKRRCGWLDLVLLKYSTLINGYTSLNITKLDVLDTFTEIPVGVSYK-YK-GETL-
NSFPEDLLTLGNVEVEYVTLPGWNQDITQIKKYDDLPENAKKYLKFIEDFV-KVP-----
----------------------VQWVGTGPARDSMLEKQI--
>gi|118092237|ref|XP_001235680.	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
-------------MRAEAGDNLKKLLEVEKRLFLSTEDLKIQHTEFVQNSVSASKDLQEE
LANIEKKKEELADYL-------CEDRKKMSLEDVFNTMKTFRELFL---KA-LQGGNNAG
HTVVV-----DGKEY-DFHLFPSGIINPKAISFIGNGVVIHLPGLFEEAEKN-EKKG--L
KDWEKRLIISDRAHI-----------------------VFDFHQAVDGLQEVQR--QAQE
GKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEFSSRFKNLAQQYKSMFPTLDI
DIEGQLKKLKGYAEKIRPM--VRDGVYFMYEALHGS-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGVPPQHVGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQSRGHEW
GVTTGRKRRCGWLDLVILKYAHMINGFTALALTKLDILDVLDEIKIGVAYK-LG-GKRI-
PYFPANQEILQKVEVEYETMPGWKTDTTGARKWEDLPPKAQNYIRCVENHV-GVP-----
----------------------VKWVGVGKSRESMIQLF---
>gi|154425984|gb|AAI51542.1|	Bos taurus
------------------------------------------------------------
-----------------------------------------------------RAAQFAH
FKLPASHLGSPRVSGAMAFAETNPATSSLPNGDC----------------------GRPR
TRPGGNRVTVVLGAQ--W----GDEGK----GKVVDLLAQDADIVC---RC--QGGNNAG
HTVVV-----DSVEY-DFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKN-VQKGKGL
EGWEKRLIISDRAHI-----------------------VFDFHQAADGIQEQQR--QEQA
GKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FGGFSERFKVLANQYKSIYPTLEI
DIEGELQKLKGYMERIKPM--VRDGVYFLYEALHGP-PKKILVEGANAALLDIDFGTYPF
VTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREF
GVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYK-LD-GEII-
PHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPINAQNYVRFIEDEL-QIP-----
----------------------VKWIGVGKSRESMIQLF---
