>gi|7573508|emb|CAB87810.1|	Drosophila melanogaster
------------------------------------------------------------
--------MRRADAFAVSLCV---------------------------------------
------------------------------------------------ILALLQTMEPVK
AEG-------------------------------KYTIVGPGTIHSHRDYNVAVAVHQTK
EPVTLKVGITGPSYNKTE----TVELATAGEFK-QITFKLPPLEA-----GEYNLTAEG-
--VKG--LEFKNSTKLNWENFKPYIKIQTDKGKYKPGDTINYRVIFLDENLRPDT--AKD
EVVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFATLGSWSLHV-QNGDQHHDGGIYF
GGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSVKMDATQQVSVRDGEFNVVLKANYTYG
KPVNGKVLVNVHLDSTS--SW------E--NVDGKTVQTDYPG-HSVVGTADMVGGKAKL
TM---DLKDFASYLPHKTS------S--SYA-QITATVEEDFTGV-KLNETGGVQLYPYR
YEMSC-TDYSSCFSFKPDKEHELNFKITYVDGSLITDTKS-----VVKAKFTEGIRRNYA
FYAFG--TDHQEPELPTIEKKTFVFESHLNASGVAPFKVVLPD--L-PDIANFTRYYSIE
LEFVDEKRDLYTTYPY-----REPKQIENP----------SSEEEKEWFRAEVQRPKDVW
NLKIGQEYQVILNS--------------------------------------------SR
PLKYFV------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YNIVGRGNILETKRV----DLAEPQTT-------------
----------------VNVTIKPTFLTTPYGRVYFYYVDE-TGEFRYTEET-FSVEVELQ
NQIEIK-APAEVKPGADVALEIKT-SPKSF------------------------------
----------------------VGLLAVDQSVLLL--GSNNDLNKESFNWRLNGYD----
------------------------------------TSTPWQ-------GGYSYYPGERT
GVVTMTN-AYFFY-NRTAP---DYNIQGFGGSSFA--------------------MRKTT
VAHDSHVFH----SGAGGPTQAVGFSA-------------ESASASAAPVVRKNFAETWI
F--ADIESTEEEVFKWVKTIPDTITNWVVTGFSLHPQKGLGVTNDQTNIKTFQPFFVSVR
LPYSVKRGEVINVPALVFNYLPKTLDVELTLD-NEDQEYDFVDASNE---------VIGD
QK-----RTQNIRVGANEAAGASFLIRPKVIGNILLKFKAIS---------------PLA
G--DAIHKPLKVVPEGITQYQNRAFFINLKDTGE---FKNTFELEVP-EDVVPDSERVEF
GLVGDLLGPVVKNLENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKLTPALDTRIKRNL
QDG----------YQHMLHYRHDDGSFSSFGPTKWRQEDPV---RNGSTWLTAYVLRSFS
KIKDI--IDLDEHILAKGYEFLLTRQAE-NGSFTEHGEYFYSSQRS-------LLTLTAN
SLLAL-------LEEE---KPNQAAIDKAVA----YLSANTAESIE------LLPKSIAI
YALQKAKAPEA-AKQVASLKSL--AKHEDDRTWWTEDLDKLRASK-NCGRW-WCWIWSQD
VEITSYALLSLLDS-------------------------------------DQETADSVL
NTVRWLIAQRNGFGGFASSQDTVVGLTALIKFAEKSGYEAA-KWEVTVSNKGKREKTEKL
NTSEENDLLLQTVEFP----QGTKSLEFEAKGTGAAMVQISYQYNLVEKEPK--------
-PSFKIQTTVLPES-----SPANLELSVCVDYVE---EGESKESNMAILEVSLPSGY-TA
DEDSFADI--R-NIERVRLVETKNGDSVVVIYFENLAKNEEKCIRIEAY--RTHAVANQK
PSSVVLYDYYDTNKKATECYS---IK----SKLCDIC-EGD-------------------
------DCKS---KC---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|119115808|emb|CAJ18844.1|	Drosophila simulans
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------LYSVVGPGTLRSNSKYNVVVSVHKAD
GPSQIKVSLNGPSYNET-----KQIELPPMSTQ-NVEFEVPKLST-----GNYNLTAEG-
--LSG--VVFKNSTKLNYADEKPSVFVQTDKATYKPADLVQFRILFLDENTRPAK--IEK
PISVIITDGAQNRIKQLSDVKLTKGVFSGELQLSEQPVLGTWKISV-SVD----------
GDNRETK-------------SFEVDKYVLPKFEVIVDTPKAAVIDDKVIKATIRAKYTYG
KPVKGKATVSMERSYGY--FG---------NPGGNDYKQEKTI-D--------VDGKGHV
EF------DIISWTQRGQY------L--PPV-KLFAVVTEELTGN-KQNATATVVLHQQR
YMIEA---YERPDHFEANKSFIYQVVVKNVDGSPVTSSAK-----NVKIGFTNTFS----
-------YFNEMPPVSRINYEAP-----VNENGIATFNVTLPD----SKS----RYYRIF
ASFDRSMSH----LGS-----ISNFEPT------------IISREP--LKIQVNTKK---
-PRLGERVSFDVVS--------------------------------------------IE
DLPYFV------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YTIVARGNVILSDYV----DVPDGKKT-------------
----------------FTVKFTPTFSMVPKATIYVHYVV--NNDLQFEEKT-IDFEKEFS
NSIDIS-APTNAKPSEEVKLRIKT-DADSF------------------------------
----------------------VGLLGVDQSVLLL--KSGNDLSQDDIFNSLNKYQ----
------------------------------------TSTPWM-------NGYGRYPGQTS
GLVTLTN-ANYPY-NTGRL---LRFPYAFGGPKIM--------------------FSTYR
VGIRGEPED----MMYFSAPRLNYVNL----------KEIPLKQTPQRTTIRKEFPETWF
F--E---XXXXXXLTLTKKIPDTITSWVVTGFSLNPTSGIALTKSPSKIRVFQPFFVSTN
LPYSVKRGEVIAIPVVIFNYLDKTLDADVIMD-NSDQEYEFTEATNE---------VLEK
AI-DEVRRVKRVTIPANSGKSVSFMIRPKSVGFTTLKITATS---------------ALA
G--DTIHQKLKVEPEGVTQFENRAVFINLKDQPE---MSQSLDAEIP-TEVVPQSEFIEF
SXXXXLLGPTLQNLDNLVRMPYGCGEQNMVNFVPNILVLKYLEVTGRKLPSVESKARKFL
EIG----------YQRELTYKHDDGSYSAFG-------KSD---ASGSTWLTAYVMRSFH
QAGTY--TDIDPKVITAGLDFLVSKQKE-SGEFPEVGKLFDNANQN-------QLALTSF
VLLAF-------FENHELIPKYQGAIEKAVR----YVAEEADKTDD------QYSLAIAA
VALQLAKHPQA-EKVLAKLESM--ARNENDRMWWSKTTESTG----EDGRVFHWKPRSND
VEITSYVLLALL---------------------------------------EKDPAEKAL
PIIKWLISQRNSNGGFSSTQDTVIGLQALTKFAYKTGSGSG-TMDIEFSSAGESNN--TI
KVNPENSLVLQTHVLP----KSTRKVDFTAKGTGSAMVQLSYRYNLAQKEKK--------
-PSFKVTPTVKDT------PNQLLVVDICAEYVPLEDADKEKDSNMAVMEIALPSGF-VG
DDESLGKI--Q-AVDRVKRVETKNSDSTVVVYFDSLTPGDVRCLPLEAS--KAHAVAKQK
PASVSLYDYYDTDRKATEYYQ---VK----SSLCDIC-EGA-------------------
------DCGE---GCKKDWGPGVKRW----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|126310391|ref|XP_001373651.	Monodelphis domestica
------------------------------------------------------------
----------MAVQFLYAVWP---------------------------------------
------------------------------------------------------------
----------------------------------SFLVTAPSVIRPGINMSIGVELLE-N
SPFQVLVKAEVLRSQLNITVLEAEGIFERGSFGTLVLPALPLNSA----NELYELRITG-
NAQGR--TLFSDKTHLIFETKRLTVFIQTDKFLYKPKQEVKFRIVTLFSDLKPYK----T
AVDLLIKDPKSNLIQQWLDEQGDLGVISKTFRLSSNPIVGDWSIQA-RV-----------
NGQTYYQ-------------SFQVLEYVLPKFEVTLQTPLYHSLNYKSLNGTVNAKYTYG
KPVKGDVTLIFVPLSIW--GI------------KKTITKHF---E--------INGSANF
TFNDLEIKNVMNNADELRYPSDMSSP--GPV-EITAVVTESLTGI-SRNASSNVFFKAND
YTIEF---FDYATVLKPTLNYTATVKITRSDNVRLTPEEI-RNKITLTITQTNYTN----
-------YWDKWNNEDQERETVQILNYTVPENGIIHLEFPLLV----NTS-----QLQVK
ASFLESVNTLSI-HGM------------------------FRSPSMTYIQLKTASEN---
-VKAGSPFELTVSS--------------------------------------------NK
PLKELS------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YMVISQSQLVAIGKK----NAS------------------
-----------------TFSLTPENSWAPKACIIVYYVGD-DGEIINDVLK-VPVQLVFK
NKISLSWNKISAEPSENVALKVSVTQPGSL------------------------------
----------------------IGLVAVDKSVKLM--NGSNDLTEESVIHELELYNT---
GYYLG-------------------------------MFT----------NSLAVF--QEC
GLWVSTDANLVHD-----Y---LYESYRTETINGE--------------------FVEMD
KADDVVMLT----NDRNDMTDLASGGA---------------FLAGNGPSIRKHFPETWL
W--IDTNMGSRTDREFEVTVPDSITSWVATAFVISEDLGLGMTTAPVELQAFQPFFIFLN
LPYSVIRGEQFVLEVTIFNYLKDASEVMVTLE-TSD-KFDILMNSNE---------INAT
GH------QQSILVPSEDGGTVLFPIKPMYLGEIPITVTAVS---------------PSA
S--DAITQNILVKPEGIEKTYSQSLLLDLTGNKLS-TTAQSLNFTFP-PDRVIDSEKIHI
TAVGDIIGPSINGLESLIRMPYGCGEQNMINFAPNIYILNYLSNTRQLTDSVKDKTISFM
RQG----------YQRELLYQRDDGSFSAFG-------NDD---PSGSTWLSAFVLRCFL
QASSY--IDIDQDVLHRTFSWLKKHIKP-NGEFWEPGRVIHSDLQGGNNS---PVTLTAY
ILTSL-------LGFQ--TYQTSMDMRRSVE----FLESHFREGVS-----DNYTLALIS
YALSSVESTEG-REALDRLNQR--AEHEGGMQFWVSSVSKLS---------QSWQPSSLD
IEIAAYALLSHF---------------------------------------LQNRMAEGM
PIMKWLSKQRNSLGGFSSTQDTIVALHALSTFAALTMTGQT-DMRVKVTGPSVTAPT-EF
LINNKNRFISQTVELAV---TQPASVTVSASGFGFAFCQLNVVYNVKNSESSRRRRSIQD
QEAFDLDVAVKDNE----DDINHLTVNVCTRF-----RGPSK-SGMALMEVNLLSGF-AM
SPD--AIL----LSDTIKKVENDHG--QVNLYLDSV-NETQFCVDVPAV--RNFKVSNTQ
DASVSIVDYYEPRRQAVRSYN---SKVMLGVSPCDLCDKKQ-------------------
------DCK----LCTDSSPTLFQHSAVVSFGCFLFLLLQIWL-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|21955142|ref|NP_665722.1|	Rattus norvegicus
------------------------------------------------------------
---------MRRNQLPIPVFL---------------------------------------
------------------------------------------------LLLLLLPRDATA
ATG--KP---------------------------RYVVLVPSELYAGVPEKVCVHLNHLN
ETVTLNVTLEYGVQYSNLL---IDQAVDKDSSY-CSSFTISRPLS---PSALIAVEIKG-
---PT--HHFIKKKSMWITKAESPVFVQTDKPIYKPGQTVKFRVVSVDISFRPVN---ET
FPVVYIENPKRNRIFQWQNVDLPGGLHQLSFPLSVEPALGIYKVVV-QKD----------
SGKKIEH-------------SFEVKEYVLPKFEVQVKMPKTMAFLEEELVVTACGLYTYG
KPVPGLVTMKVCRKYTQ--SY---SNCH--GQHSKSICEEFSK-Q--------ADEKGCF
RQ---VVKTKVFQPRQKGY------D--MKI-EVEAKIKEDGTGI-ELTGTGSCEIANTL
SKLKF---TKANTFYRPGLPFFGQVLLVDEKGQPIPNKNL-----TVQVNSVR-------
-------SQFTFT---------------TDEHGLANILIDTTN--F-TFS-----FMGIR
VIYKQNNICFD--NWW-----VDEYHTQADHSAAR-----IFSPSRSYIQLELVLGT---
-LACGQTQEIRIHFLLNEDALKD-----------------------------------AK
DLTFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLIKARGSIFNSGSH----VFPLEQGK-------------
------------VKGVVSFPIRVEPGMAPVAKLIVYTILP-NEELIADVQK-FDIEKCFA
NTVNLSFPSAQSLPASDTHLTVKA-TPLSL------------------------------
----------------------CALTAVDQSVLLL--KPEAKLSPQSIYNLLPQKAE---
QGA-YLGPLPYKGG--ENC---IKAED-ITHNGI--VYTPKQ--DLNDNDAYSVF--QSI
GLKIFTN-TRVHK-PRYCP---MYQAY-P---PLP--------------------YVGE-
-PQALAMSA----IPGAGYRSSNIRTS----SMMMMGASEVAQEVEVRETVRKYFPETWI
W--DMVPLDLSGDGELPVKVPDTITEWKASAFCLSGTTGLGLS-STISHKVFQPFFLELT
LPYSVVRGEAFILKATVLNYMPHCIRIHVSLE-MSP-DFLAVPVGSH-------------
--------EDSHCICGNERKTVSWAVTPKSLGEVNFTATAEA-LQSPELCGNKVAEVPAL
VQKDTVVKPVIVEPEGIEKEQTYNTLLCPQDAE----LQENWTLDLP-ANVVEGSARATQ
SVLGDILGSAMQNLQNLLQMPYGCGEQNMVLFVPNIYVLEYLNETQQLTEAIKSKAISYL
ISG----------YQRQLNYQHSDGSYSTFG-------DRGMRHSQGNTWLTAFVLKAFA
QAQSY--IYIEKTHITNAFNWLSMKQRE-NGCFQQSGSLLNNAMKGGVDD---EVTLSAY
ITIAL-------LEMP--LPVTHSVVRNALF----CLETAWASISN-SQESHVYTKALLA
YAFALAGNRAKRSEVLESLNKD--AVNEEESVHWQRPKNVEENVREMRSFSYKPRAPSAE
VEMTAYVLLAYLTSASSRPTR----------------------------DLSSSDLTTAS
KIVKWISKQQNSHGGFSSTQDTVVALQALSKYGAATFTKSNKEVSVTIESSGTVSG--TL
HVNNGNRLLLQEVRLA----DLPGNYITKVSGSGCVYLQTSLKYNILPEAEGE-------
-APFTLKVNTLPLNFDKAEHHRKFQIHINVSY-----IGERPNSNMVIVDVKMVSGF-IP
VKPSVKKL--Q-DQSNIQRTEVNTN--HVLIYIEKL-TNQTMGFSFAVE--QDIPVKNLK
PAPVKVYDYYETDEFAIEEYS-------------APFSSDS-------------------
------EQGNA-------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|156542835|ref|XP_001599750.	Nasonia vitripennis
------------------------------------------------------------
---MTTAKRTSPGKIPSQRWT---------------------------------------
-----------------------------------------------GHLGPLLLLFCGL
TSGQSR----------------------------YYSIVAPRVVRPNSEYHVAVSIVGVS
EPTTTFVELSGQLDSGESFAVSENIIVEPYATR-VLSLEIGDTGP-----GRYRLLARG-
--ISG--YEFVNSTELDYAHKSYSVFVQTDRSVYKPGSKIQFRCIVLDSRLRPTA---NR
QLEIYITDGQGNRIKQWERPRLHQGIFNGELELSQSPVLGDWEIVA-EI-----------
GGQTFKK-------------AIQVAEYVLPKFEVTIDSPPHATFKEGKITVLVHAKYTYG
KPVKGEATITAFPDIYS-------GVLQ--PIYSPPIRKTVN-----------IDGKTTV
DF---DIANDLK--YDDDY------K--RPV-VIEVAVEEAVTGR-RQNNSMQITLHKHK
YTMEL---LRTAEYYKPGLKYTAFLKVTYHDGSPVVDNTN-----PVHISYG--------
-------YTYNSEDLHNITRM-------LDKNGMVELDFYPPL----SMPDKIFRPLRIE
AQYLNL-------HEW-----FPSTNPA-------------TSRSESYIQAMLRTDK---
-PKVNEYVEIEVNS--------------------------------------------TH
PLKYLS------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YQILGRGDVLNAASI----QISDRYTA-------------
-----------------TFKFLATYVMAPIAHVVVYYVRE-DSELVADSLD-VELEGTLQ
NFVDIKPVSDEVGPGDNIDLTITA-KPNSY------------------------------
----------------------VGLLGVDQRSLLL--KSGNDITYDQVRKELMSYDV---
NDAAFYDQED--------------------------YEHSWI--RPGSANADEVF--RKT
GTVVLTN-GYVHKNPQLTYPEEEGDRLKNPAQGIS--------------------ISTLR
PDIGPPVKH----RFATRPAWAGRYAF----------SYVPLLPWRPRVFLMHDISDTWL
F--SNMSSGYEGKTVIRRTVPDTITSWVLTGFSVDPAFGLGLIEAPRKLRVFKPFFLSMN
LPYSVIRGEIVAIPIVVFNYMSKDLNVEVVLE-NNG-DFEFAEVSNE---------VHDN
TKRLELYRTKKIFVKANSAESVAFMIVPTKLNHITIKAKATS---------------VMA
G--DSVEYPLLVKAEGETQYRNKVVFVDLRDTDS---MKTNVTVDIP-KHFVSDSEYVEV
SAVGDILGPSIPNLSKLIKMPFGCGEQNMLNFVPNIVILDYLKNTNQLSPAIESKSIRYL
ETG----------YQQELTYRHTDGSFSAFG-------KTD---PSGSTWLTAFVAKSFK
QAEKY--ITVEEKIIADALKWLAEKQAP-NGSFPEVGTVSHRDMQGGAAK---GLALTAY
VLSAF-------LEVENIEGRYRNVIYKGVD----YVVRNMQGIDD------NYALSICT
YVLSLARNAYE-DEAFRLLDSK--ATTKDEQKWWSKPIPEDD----KKNPW-FSLSRTVD
VEMTSYALLAYL---------------------------------------RRNQLSDAA
AIMKWLVKQRNAEGGFASTQDTVVGLYALAKLGEKLRTNVY-DVQVRITTDVGESK--EI
NINSRNFMIVQKHLLL----SRTRAINITATGTGFALVQVASRYNLNVTGAF--------
-PLFTLDPQVDKIS-----TNDHLQLSICSGFIP---TKEANESNMAVMEVSFPSGF-TV
DQDALPSL--E-LSQNVKRVETKNGDTMVVLYFDKMVHDKSYCPTVSAY--RTHKVAKQK
PVPVSIYDYYDSSRRARVFYE---PKM---TTLCDIC-EDE-------------------
------QCGD---VCSIKAGK-----------REDGTLPSV-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------SSSSTTLGNFALILACA
Y-------------------------YIALNSRR
>gi|91083795|ref|XP_972838.1|	Tribolium castaneum
------------------------------------------------------------
-----------MWK----------------------------------------------
------------------------------------------------IVIFGFVIACVR
CQG-------------------------------FYKVVGPRAVRPNSEYHVAVSIQQTS
EPTTVRATLQGISPNGSIYTSDDRVEVQPYTSR-ILRLEVGDVDS-----GDYKLVVSG-
--KGG--VDFYSDYPVEFVEKSYSVFIQTDRAVYKPGSKVLFRAVVLNSQLKPAAEVRNE
LLHIFVTDGQGNRIKEWKGIQALRGVFTGEVKLSESPVLGNWNISV-KI-----------
HGQTFSK-------------SIEVAEYILPKFIVNIQAPKHMTFKENVLVANIQTQYNYG
KKVKGEATVTVYPTIFS-------GVIQ--PIFQNPIRKVIP-----------IEGSATV
TF---DIAKELK--LTDEY------E--RVV-MVDVTVEEASTGR-RQNNSVEVHLHKYN
YKMDL---IKTADYFKPGLKYTAYVKVSSHEGTPLRSENR-----EVTVRYGYSRADEVY
-------VTEKHR---------------LDKNGVAKLEYYTPVNVT-NTT-----ALRIE
AQYQDLKER------------ISPIPA-------------AVSYSNTFLQVSLETER---
-PIVNLDVEILVNC--------------------------------------------TE
RLRYIS------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YVLMGRGDVLNANTF----QVDNMHE--------------
----------------YRFHFTATHAMVPVAHLIVSYVRD-DGELVGDALD-IEVDGLLQ
NYMEIQVNPVETEPELDIDIAIRA-QPNSY------------------------------
----------------------VAIMAVDQNAVKM--RPGFDLTHSEVAEELKKYDPAQQ
SPYSMIMHDSKYHF----------------------FWKPGA------ANPHSAI--YNS
GADLLTN-SHVDRHQPTLE-----DIYLRPVFYGT---------------------STVK
PDRGFGLPL----HTVTRPPLAGPYAF---------SRIPKPVWNKPKVYLTEEIADTWL
F--TNFSSGYEGKTSIRRKIPSSLNTWVVTGFSLDPIHGLGLTTTSKKVKVSKSFVVTLD
LPFSVQRREILAVPVVVYNYMDKDVNAEVTLH-NPEQKFEFAEVSNN---------VNST
RK-VELYRRKKINIKRNSGTSVSFMIRPLKQDTIEIKVTANS---------------PKN
Q--DVAIKHLQVTTEGETEYYTKTVLIDLRNNPN---YKKSINFTIP-QNMVTGSEKIEV
SAVGDLLGPTMVHLENLIRLPTGCGEQNLIHLMPNLIILQYLRYTRQVTPTIQNEALDLL
EKG----------YQQQLSYKRKDGSFSAFG-------MRD---EKSSVWVTAYVALTLR
QAKGH--IYVDEKIIEGCLEWLANIQGR-NGSFVEVGSVIYKEIQSREGN---SLALTAF
TLLAF-------IENQKYASTYSNTINKGLD----YIARYISEQES------IHTIALCS
YTLQLARHPSK-QSAFNLLDLR--SKSRGNLKWWSKDVPSNE----IKNPW-NKLPRSID
IETSAYGLLTFL---------------------------------------EANYFEDAI
PVLNWLLDQQNSLGGFTSSQDTFVGLWAIYKLVLKLATNV--NMQVEFTYGKDQRH--NF
NVNKNNAMIVQKLQLP----KDIREVNVTAQGKGLAVFRVSYEYNMNVTGPW--------
-PMFTLDPQVDKNS-----NKDHLQVSICTGFVSRN-LSETPESNMAVMEVNLPSGF-TA
DIDSLPSL--E-VSQNVQKVETSNGLTRVTLYFNNVSSVNEYCPTVSAF--RTHKVANQK
PVSVIIFDYYDSSRRARQFYR---SRT---STLCDIC-EDE-------------------
------DCGD---ICTSKANPQVG---------EDSQEGKG-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------SSAALRSSWLGFLVVMF
A-------------------------IVQL----
>gi|22901939|gb|AAN10129.1|	Ornithodoros moubata
------------------------------------------------------------
-----------MARNPAIICL---------------------------------------
------------------------------------------------LISCLLASSHLA
QSG--------------------------------YIFTAPKVLRSHRPAVFRLTLTDVG
VDGQVSVRLLNYNNESLVLAHQVYDIKQGELEQ-TLNFDVPEYSG-----SSAKIEVSG-
-TFGE--YMFSGKKEIDFQKSKDHILIQTDKALYKPGQKVQLRVLPVTSDLTPVT---DA
VAEIYVSSPSEARIAQWKNVTFERGIVQFDFKLTEEPELGLWQIVV-EL-----------
PSQTVRQ-------------HFEVNEYVLPKFEVTVTPPSYLLANAKEIVWKICATYTFG
QPVEGTLLANVTYEKYH--W----------ETESFPYVEHEGP----------ING--CF
DF---VVNTTALRFNENYQ-----VY--KRL-QLFAQVNETGTGI-TLNKTSYISRTSNP
LELKFIAEEHGNNYFKPLMPYYGTLLVKKPDGVPLPGELI-----QLCLLTQSEIIKTLW
WRTDRRLSCKNYT---------------SDALGLVKFTLPPLQ----TTV----VTVSVE
ATAVNYEAEKYDTYGT-----RINQPKTPSTCKRG-------TRQQQLCPNQPSKDP---
-LSCTSNYKVQLLYTADP----------------------------------------DA
DYLFH-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YQIVSRGQILTDGTIPGKFTASEAVPAVVDDSYLQEEVRN
ESLPSNVAENVSNVGSLEIELAPDSRYVPLAKLLVFYVRP-DGEVIADSQE-FEVEKCLK
NNVTFRFGSESVQPATSAAIHLTG-SPLSF------------------------------
----------------------CGVGVVDKSVHLL--KDDNQLTKAKVYDLLKRLDI---
NRYTWPRQSSYDYC--RRK---SSSTGPRYARRV--IWPGPRTSNVEYVDSITAF--DES
GVIVLSD-LTLET-RPCRE---AIYDRPPSAFAAP--------------------ASGPA
GLFGPPAPS----PPRMSIPSPVRPVAESFDAALPGAPGPAGVPAKSAVEVRTYFPETWL
W--ELKELDEHGNLDFKEKIPHTVTEWVGSAVCINNQDGIGVS-DPARIKAFQPFFASFS
LPYSVIRGEVFPVTLSVFNYLDKCLPVELTLA-ESE-DFEFLEERTK-------------
----------TLCVCGSKVVEK-FSVKPKTIGEVNVTVFAVG-SENSEVCGDK--PVEKV
VAKDAVTQPLLVEAEGFPKEETRSVFICSQGEAG---EKPQFELALP-EDVVEGSARAYV
AVSGDIMGPAIKNLDSLVQVPTGCGEQNMVKFTPNVYVLDYLKATGKQDADIEKKAVENL
KTG----------YQRQQKYRHSDGSYSAFG-------TND---RQGSLFLTAFVIRSFK
QAERY--IPIDEKMLQQSVNWVLNKQIPVNGCFNNVGRVLSSGLKGKVNE-SNPGPLTAY
VLAAL-------LEGG---LAHSNLTEGALH----CIDAQKNPSPH--------NLALSV
YATALAGQDV--SAKLEALESL--AVHDGALTHWRNGGA------------------SAD
VETAAYAVLTYVKLG------------------------------------GQENLNKAQ
PIIKWMATKRNSRGGFSSTQDTVLGLQALSAFSSQLSKDPV-DLAVKVSGEQVEE---SY
DLKEDSKLVLQQRKVV----NLPNTLTGETTGTGCALISTTLKYNVHTAPTS--------
-QGFELAVTPVLDP-----TCTSALLRVCTKF-----DGEQP-SNMAVVELKLVSGY-TI
SDDDIKEIYQK-ADVALKRHEIDRN--QVNFYFEEV-TSEEKCFEVTVH--KEFEVVDAK
PATVKVYDYYQLENAKSVSYS------------LTGCESPQ-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|114107595|gb|AAI22897.1|	Xenopus tropicalis
------------------------------------------------------------
--------QHGATDTMLLRAL---------------------------------------
------------------------------------------------HVGLLLLQLSGA
LGA--KL---------------------------QYAVIFPSEMVYPQSEQACVHLEGAD
GGSRIHITLQMGKHNTTVL---EKTSQQKSYFR-CITFEVPPPTNGNEEVATMQVSIES-
---GG--ETISNSRRVLVKRARTSLFVQTDKAVYKPGQTVRFRVVSLKENLQPEE---SQ
VPTIELQDPGKNRIGQWLNVSLQQGIAELSLPLSSEPSLGEYSIRV--------------
--KDTVH-------------HFSVEEYVLPRFEVTLQLPRVVAVNSKQFAVNICARYTYG
KPVQGTYKVNVCRKHYS--YR---TMVA--SDQGRDLCADFSG-T--------LSQSGCS
TL---DVQSSTYNLLLSEW------Q--LNL-EGTGSVLEDGTGI-EISASGRSQISSQL
TTVTF---LDADDTYKPGISYIGTVKVVDASDTPIPNQTV-----YLTSLDGM-------
-------VNQTLE---------------TDENGLAPFKLENTAEWK-VKV-----FLTAK
IQKEEPLRKYQ--YGV-----INPSHGSAFLTISR-----FHSLSNSFLKLYAQKGE---
-LLCEGQQEVRVEYLIKRTVLEEG----------------------------------AK
HLELH-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLTVSKGAIKDCDFL----EVPINNED-------------
----------EVLRGEVSIKLDLSADVSPTLRVLTYILLP-GGDMPADSAT-FKLQRCFR
NKVSVGFSPDEVLPGADVSLQVQA-AAGSL------------------------------
----------------------CGLRVVDQSVVLM--KPDKELTANKIHDLFPSRDF---
GYYDYRIQEYDDHCPFFPY--WRPWN--RFFKRS--I-QPWH--FPEERDVYSLF--KKM
RIKIITN-ADIKK-PVECQ---HYDFRGPGLPGMP------------------GIPGDRR
VVMASPSIERDVMVGAAMPDTIQQPEP------------------EAAEIIRTYFPETWI
W--ELAPVGESGRAEVHHSAPDTITEWNAGAFCMGP-SGFGIS-PPTSLRVFQPFFVELT
LPYSVVRGESFTLKASVFNYLKQCIKVQTTLL-PSQ-ELEQEPCADC-------------
--------QYSSCLCAEESKTFYWNLKASNLGEVNVTVKTEA-LDTQDLCNNEFPIVPKQ
GRSDTVVKPLLVQPGGVLIEKSHSSLLCCQAGEDH-PKTEEISLKVP-ENILKDSERAYA
TVLGDLMGTAMQNLGRLLAMPYGCGEQNMALFAPNIFILQYLTKTRQLTPEVQSKAKGFL
ESG----------YQRQLTYKRNDGSYSAFG-------QRD---KEGNTWLTAFVVNSFS
KARPY--IFIDESHLNHSFSWLRDNRNE-SGCFRSVGRLFNNALKGGIDD---ETSLSTY
VTMAL-------LEAG--VSVQDPVVADALS----CLRKAAKDVSS------VYTQALLA
YTFTLSKDIELREMLLAKLEEK--AVRNEGQLHWERKPATV-----PSDLPYWYRAPSAE
VELTSYVLLAHLSG-------------------------------------PNKDLGKAS
EIVNWLSKQQNPYGGFSSTQDTVVALQALAKYGEATFTDKG-DVTATVTSKTGFHQ--QF
HVDQTNRLLLQKASLP----DIPGEYSLSATGSGCVYVQTVLRYNIPPPRSD--------
-ATFSVRVETEPDKCPQ-DQLKVLKISMTAQY-----TGSREKSNMAVIECKMLSGF-IP
VKSSVRKL--E-KSKTIKRSEILTE--KVTLYLDEL-GHEPLHLSFMVE--QDIVVKNLK
PATVKVYDYYDTEEEAVAEYN-------------SPCGSDG-------------------
------DKGNAK------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|109095614|ref|XP_001118458.	Macaca mulatta
MTPARTQHFLAGQTYALPFIPPDLQGEEAVQRAADALQRLQKVS----------------
------GDILSRWELPPTPTC---------------------------------------
------------------------------------------------SEEVVLGSPFSS
PNN--TPSGSSPFGIPGPGGPSWLPWVEGPR---QYVLLIPSVLQEGSLDKACAQLFNLT
ESVVLTVSLNYGEVQTKMF---EENVTGENFFK-CISFEVPQARS--DPLAFITFSAKG-
---AT--LNLEERRSVAIRSRENLVFVQTDKPIYKPGQKVMFRVVSLDDHLKPLD---EM
YPVITLQDPEGNRIQQWVNEESVGGILQLSFQLISEPILGWYRITV-EML----------
NEKKTYH-------------SFSVEEYVLPKFQMTVDAPENILVVDSEFKVNVCALYTYG
EPVDGKVQLSVCRESTA--YH---SC----GRPISSLCKNFTI-Q--------LGKDGCV
SK---FINTEAFELNREGY------W--SFL-EVHALVTEDGTGV-QLTGSKYVYIDSSV
VKISF---ENMDMSYKQGLPYFGQIKLLNPDNSPIPNEVV-----QLHLKDK--------
-------VVGNYT---------------TDANGIAQFFLDTST--F-TYP-----NITLK
AAYKANENCEA--HGW-----VLPQYPQPEYFAYR-----FYSKTNSFLKIVQEMEE---
-LRCNQQKRVLVHYILNMEDFEDK----------------------------------TY
TANFN-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLVISKGVIVLHGQQ----KIEINENG-------------
------------RKGIFSISIDVSPELAPSVDMLVYSLHP-GGEMVTDSTQ-FQIEKCFK
HQVNLNFSKEKSLPGSNVNLQVSA-ASNSL------------------------------
----------------------CALWAVDQSVLLL--RSYGQLSAQSVYSQLYSREL---
HGY-YFRGLNLEDGLKVPC---LKDEH-ILYNGI--YYTPAW--ADFGKDAYDLV--KAM
GLKIFTN-SHLRK-PVLCK---DSNHL-----DYT--------------------D---Y
ISLEAYTGS----DLKSEFHG---------------------------ETLRKSFPETWV
W--NLITTDSSGAANLRLTVPDTITQWKASGFCMNDKAGFGLS-PTVSMTAFQPFFVDLT
LPYSVVRGEAFTLKANVFNYLKSCIQVNTVLK-ASS-VYQARLLSTE-------------
--------HENICICGNEKKSFTWLVTPQTLGTVNLTVTAET--LQNSGCGNGSSTAPDI
GWRDTLIKPLLVEPEGIEKEMTQGSLICTNGST----VSQPVVLTLP-DNLVKDSPRAYW
SVLGDILGSAMQNLQNLLHLPFGCGEQNMALFTPNIYILDYLSQTQQLTEEIKSKIIGYL
TTG----------YQRQLSYKHFDGSYSTFG-------HKD---EHGHTWLTAFVYKSFA
QAKRY--IYIDDKVQSQTLIWLLNIQKP-DGCFLNFGKVFNNALKGKEDN---EISLTAY
VIGAL-------LEAD--HPVSFMAIQKGLQ----CLETVSRERAM-----TTYEQALLA
YTYSLVGYEDKREFFFNELNKK--AKRVGGSVYWELEERFSME---GSSSLYYPQASSAD
IEMTCYGLLALLFKPQL----------------------------------TSEELSYAS
QIVHWVAKQQNSRGGFFSTKDTIVALQALTLFQRLTFSKNR-QNSVQIFSDQGFNT--AF
QVNDKNRLLLQQIPLP----TTKGKYMVEVNGNGCVYVQSTLRYNILLPKKS--------
-SGFSLSVNTANAFCRG-LFDAKFDLVVSASY-----YGKRNSSNMAIIDVKMLSGF-VP
DRSSVKKL--Q-EDGKVQRVEIKTT--HVFFYLENV-TQKEIQFSFSIK--QDALVSNIK
PASVQLYDYYETGHRLSEEPFL--RRQAWVHSRGLYCLGSH--------------SAIHI
SKDGLQGDGHVVEACDRVAPVSRGKSSGFLFPFRVQS-----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|149712699|ref|XP_001493638.	Equus caballus
------------------------------------------------------------
---------MKGNQLPNPVLI---------------------------------------
-------------------------------------------------LLFLLLPRDAS
ATS--KP---------------------------QYLVLVPSQLYSGVPEKACILLNHLN
ETVTLSVTLEYGRQSRNLL---TDLVTEKNSFY-CSPFIIPELPS---ASAFITVQVKG-
---PT--LQFINRKSVQITQAESLVFVQTDKPTYKPGQTVRFRIVSVDVSFHPLN---EM
FPVVYIENPKRNRIFQWQSLKLQGGLSQLSLPLSAEPALGPYKVVL-QKE----------
SGRKIEH-------------SFEVIEYVLPKFEVQVKMPKTIGFLDKEFVVSVCGLYTYG
KPVSGLVTINICRKYSR--YY---STCH--GKHSQSICEEFSQ-Q--------ADNEGCF
TQ---FVKTKIFQLRQKLY------D--MTI-QVEAKVREEGTGL-ELTGHGSCEITNTL
SKLKF---IKVDSHYRCGLPFFGQILLVDEKDKPIPNETI-----VVAVDLNR-------
-------YRSSYT---------------TNEHGLVDISIDTTN--F-TSS-----FITVT
VTYKENNQCFD--HWW-----LSEFHTQAQHTAKR-----IFSPSKSYVRLEPVAGT---
-MTCGQTQEIRAHYILNGQILQD-----------------------------------EK
DLTFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLIQARGSISQSGIH----VLSIKQGD-------------
------------MKGVFSFSFQVKSDNAPSAQLLVYTILP-NGEIVADTGT-LEIENCFA
NKVNLSFSSARNLPASNTTLKVTA-TPHSL------------------------------
----------------------CALRAVDQSVLLM--KPEAELSPQSVYNLLPEKNL---
-FSVSYRGPANEDG--QKC---IHAED-ITHNGI--IYTPKQ--ILDDDDVYSIF--ESV
GLNIFTN-SKIHK-PRFCQ---LPHGY--PAMPMP--------------------YLGGK
VPQGLALAS----GAAGAVYPTMMREE--------------FPATEVKGTVRKYFPETWI
W--DLVPLDSSGGSELAKQVPDTITEWKANALCLSKTTGLGLS-PIISLQVFQPFFLELT
LPYSVVRGEDFILKATVFNYLFHCIRVSVQLD-ISP-AFSAVPVEKN-------------
--------EDSHCVCGNGQKTVSWAVTPKSPGKVNFTATAEA-LRSQELCGNEVPEVPAF
GQKDTVVKPLLVELEGIEKEETFNTLLCASETG----VPEKLSLKVP-SDVVKGSARATY
SVLGDILGSAMQNLQNLLQMPYGCGEQNMVLFVPNIYVLNYLSETQQLTEKIKSKAISHL
ISG----------YQRQLNYKHSDGSYSTFG-------DHDGR-SQGNTWLTAFVLKSFA
QARSY--IYVEDSHITNSLTWLSQKQKE-NGCFQSSGLLLNNAIKGGVDD---EVTLSAY
ITIAL-------LEMP--LPVTHQVVRNALF----CLENAWRSTSE-AQGSLVYIKALLA
YAFALAGNQAKRSELLESLDKE--AVKEEDSIHWQRPGKFQE----AKELYYQPRAPSAE
VEMTSYLLLAYLTAQPAP---------------------------------SSEDLSVAS
RIVKWITKQQNPNGGFSSTQDTVVALQALSKYGAATFTKREKEAIVTVKSSRTFSE--EF
QVDDTNRLLLQEVELP----EIPGEYSTTVSGSGCVYLQTSLRYNILPKKEGK-------
-VPFTLKVDPLAKNCDGIDVHRKFQIHINISY-----TGERPSSNMVIVDVKMVSGF-IP
VKTSVKKL--Q-ERPQIQRTEVSTN--HVLIYFEEL-TNQTLSFAFSVE--QCIQIKNLK
PATVKAYDYYETEEFTIEEYS-------------DPCLAGN-----------VNVSVSAE
AVQSLKLCGNEVAEVPEMEREDMVIKTLLVEGGVEDEVTLYAYVTVALWRVLFLSL----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|119893035|ref|XP_591612.3|	Bos taurus
------------------------------------------------------------
---------MGKNKLLYPSLT---------------------------------------
------------------------------------------------LLLLLLLPTDAS
VSG--KP---------------------------QYMVLVPSLLHTETPEKGCLLLSHLN
ETVTVSASLESVRENRSLF---TDVVAEKDLFH-CVSFTLPRSPT-SQEVMFLTIQVKG-
---PT--QEFKKRTTVLVKNEESLVFVQTDKPIYKPEQTVKFRIVLLDESFHPLN---EL
VPLVYVEDPKGNRIAQWQNLEVENGLQQLTFPLSSEPFQGSYKVVV-QKG----------
SGGTAEH-------------PFTVEEFVLPKFEVQVRMPKIITILEEEVQVSVCGLYTYG
KPVPGRVTMNMCRKYRN--P----SNCY--GEESNAVCEKFSG-E--------LNNEGCF
SQ---QVNTKIFQLKRQEF------E--MKI-EVEAKIQEEGTEV-ELTGKGATEITTTI
TKLSF---VTVDSNLRRGIPFTGKVLLVDGKGVPMPNKVI-----FITANEAN-------
-------HNSNTT---------------TDEHGLAQFSITTTK--I-KGT-----SLSIR
VKYKDHSPCYG--YQW-----LSEEHQDAYHSANL-----VFSRSNSFVYLEPLPRE---
-LPCGKTQTVQAHYVLKGQVLKD-----------------------------------LK
ELVFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLIMAKGGIVRSGTH----TLPVEQGD-------------
------------MQGHFSMSVPVESDIAPVARLLIYAILP-DGEVVGDSAR-YEIEHCLA
NKVGLNFSPGQSFPASQAHLRVTA-SPQSL------------------------------
----------------------CALRAVDQSVLLM--RPEAELSAATVYNLLPVKDL---
SSFPSSVNQQEEDN--EDC---ISHDN-VYINGI--MYFPVS--NTNEKDMYSFL--QDM
GLKAFTN-SKIHK-PKICP---QPEEHRIQGKEGL--------------------ERVWF
FFAPEMGRN----RDFVHFDD---------------------TSEPPTETVRKYFPETWI
W--DLVVVSSSGVHEVEVTVPDTITEWKAGALCLSRDTGLGLS-PTASLRVFQPFFVELT
MPYSVIRGEAFTLKATVLNYLPKCIRVSVQLE-ASP-AFLAVP-EKE-------------
--------QETYCICGNGRQTVSWAVTPKSLGNVNFTVSAEA-VESQELCGSEVPVVPEH
GRKDTIIKPLLVEPEGLEKEVIFNSLLCPSGAK----VSESLSLKLP-PNVVEESARASF
SVLGDILGSAMRNTQNLLQMPYGCGEQNMARFAPNIYVLDYLNETQQLTAELKSKAILYL
NTG----------YQRQLLYKHFDGSYSTFG-------EHRGN-SEGNTWLTAFVLKSFA
QARGY--IFIDEAHITEALTWLAQKQKS-NGCFRSTGTLLNNAIKGGVDD---EVTLSAY
ITIAL-------LEMP--LPVTHPVVRNALF----CLDSAWKSAKEGSQGSHVYTKALLA
YAFALAGNQERRTEVLTSLYEE--AVKEDNTIHWTRPQKPRL----LTEDIYQPRAPSAE
VEMTAYVILAHVTAQPAP---------------------------------NPEDLKRAT
SIVKWISKQQNCQGGFSSTQDTVVALHALSRYGAATFTSARKAAQVTIQSSGTFST--KF
QVENSNRLLLQQVSLP----EVPGEYSMSVTGEGCVYLQTSLKYNILPKKDE--------
-FPFALEVQTLPQTCDGPKAHTSFQISLSVSY-----IGSRPASNMAIVDVKMVSGF-IP
LKPTVKML--E-RSN-VSRTEVSNN--HVLIYLDKV-TNETLTLTFTVL--QDIPVRDLK
PAIVKVYDYYETDEFAVAEYS-------------APCSKDI-------------------
------GNA---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|148667253|gb|EDK99669.1|	Mus musculus
------------------------------------------------------------
---------MGKSRWAQLCLF---------------------------------------
------------------------------------------------SVLLAFLTSASS
LNG--YS---------------------------KYMVLVPSQLYTETPEKICLHLYHLN
ETVTITASLVSQWGRRNLF---NELVVDKDLFQ-CVSFIIPRFSS-SDEEQFLYVDIKG-
---PT--HNFSKKEAVLVRNKESVVFVQTDKPVYKPGQSVKFRVVSMDKNLRPLN---EL
-------DPKKNRIMQWKDIKTENGLKQISFSLAAEPIQGPYKIVL-QKQ----------
SGVKEKH-------------SFNVMEFVLPRFDVALKVPNAISVNDEVLSVTACAKYTYG
KPVPGYVEISVCH-------------------ETEAGCKEVNS-Q--------LDNNGCS
TQ---EVNITELQPKKRHH------R--VQLFHVNATVTEEGTGL-EFSRSGTTKIERTT
NKLIF---LKADSHFRHGIPFFVKVLLVDIKGDPIPNEKV-----FIKAQELG-------
-------YTSATT---------------TDQQGLAKFCIDTDG--F-SGS-----SLHIK
VKHKEEDSYSH--FYC-----MEERYASADHVAYA-----VSSLSKSYIYLDTETSS---
ILPCNQIHTVQAHFILKWD-FGV-----------------------------------LK
ELVFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLVMAQGSIIQTGNH----THQVEPGE-------------
----------APVKGNFALEIPVEFSMVPLAKMLIYTILP-DGEVIADSVN-FEIEKCLR
NKVDLSFSSSQSLPASQTRLQVTA-SPQSL------------------------------
----------------------CGLRAVDQSVLLL--KPEAELSPSWIYNLPGMQH----
NKFISSSHLPEDQEDCILCG--------SWVAEKHTNSVPHG----REKDVYRYV--EDM
GLMAFTN-LKIKH-PTFCF---DYDMVPILAPRVE--------------------FDLAF
SHENTGSLH----TVLSKRPEETPRKD-------------PPSNDPFTETIRKYFPETWV
W--DIVTVNSTGVAEVEMTVPDTITEWKAGALCLSNDTGLGLS-SVAPLQVFQDFFVEVS
FPYSVVRGEAFMLKATVMNYLPTSMQMSVQLQ-DSP-DFTAVPVGDY-------------
--------QDSYCLSAKERYTSSWLVTPKSLGNVNFSVSAEA-QQSPEPCGSEVATVPET
GRKDTVVKFLIVEPEGIKIEHTFSSLLCASDAE----ISEKLSLVLP-PTVVKDSARAHF
SVMGDVLSPAIKNTQNLLHMPYGCGEQNMVLFAPNIYVLKYLNETHQLTQTIKTKALGFL
RAGQTHPKPCIPGYQRELNYKHKDGSYSAFG-------DQNGE-REGNTWLTAFVLKSFA
QARAF--IFIDESHITHSLTWLSQQQKD-NGCFQSSGSLFNNAMKGGVDD---EMTLSAY
ITMAL-------LESS--LPATHPVVSKALS----CLELSWKTIEQERNASFVYTKALMA
YAFALVGNQDKRDEILKSLDEE--AIKENNSIHWKRPQKPRK----SEHHLYKPQASSAE
VEMNAYVVLARLTAQPAP---------------------------------SPEDLTLSM
STIMWLTEQQNSNGGFSSTQDTVVALDALSKYKAVTFSRSQKTTLVTIQSSGSFSQ--KF
QVENSNRLLLQQVALP----DIPGDYTMSVSGEGCVYAQTTLRYNIHLEKQP--------
-SAFALRVQTVPLTCNDPKGHNSFQISLEISY-----TGSRPASNMVIADVKMLSGF-IP
LKPTVKKL--E-SLAPVRRTEVSSN--NVLLYLDQV-NSHTLAFSFIIQ--QDFLVRNLQ
PAMVKVYDYYETDEVAFAEYS-------------NPCRTTN-------------------
KIFEALICGEGFAGIPRPRNLQDGYLCLSLKYKY--------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|1304084|dbj|BAA12316.1|	Cavia porcellus
------------------------------------------------------------
---------MGNKKLLHPNPV---------------------------------------
------------------------------------------------LLLLILLAADAS
ISG--KP---------------------------QYMVLVPSLLHSGTPEKICLLLTQLN
ETVTVKASLDTIRENGSLF---MNMVAEKDLFQ-CVAFTVPQSPY-PEAVMFLTVEVEG-
---PT--HGFRSRKTVLVKSKDSLVFVQTDKPIYKPGQTVKARVVSLDENFRPLN---EL
FPLIFIQDPKGNRVMQWQNLKLERGLTQLSFPLSSEPLLGSYSVVV-HKE----------
SGGRMHH-------------SFTVEEFVLPKFEVQVSMPKKITILEQEFTVSVCGRYTYG
KPVPGNITMSICRNYNN--P----SACL--SEESRAFCKKYNQ-Q--------LNSQGCF
IQ---QVKTNDFQLRRKEY------E--MRL-RVEAKIREEGTGV-QLTGTGFSEITATI
TKLSF---VKVDSYVRPGVPFFGQVRLVDGKNVPMPHKMI-----TITASEAN-------
-------YHSNAT---------------TDENGLVQFSINTTN--M-IGT-----SLNIQ
VKHKDSTNCYD--YQW-----LLEANEGASHTANA-----VFSLSRSFVHLEPQLGK---
-LPCHQTQTFKAHYILKGQE--------------------------------------LK
ELVFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YVIMAKGGIVQSGTY----VLSVEQGN-------------
------------TKGHFSVSVPVESDLAPVARVLIYAILP-SGEIIADSAK-YNVENCLD
NKVNLSFSEGQSLPASKTHLRVTA-SPQSL------------------------------
----------------------CALRAVDQSVLLR--KPEAVLSASSVYALLPVKDL---
TGFPGLLGQQEEND--GEC---VSLYN-TYIDGI--LYSPEP--NINEKDMYGFL--KDM
GLKVFTN-TKIQK-PQLCA---HVQKFEVPTMAYS-------------------------
----YSESS----SFRSGPRRVPAVGI------------AATYSEPPKETVRTYSPETWI
W--DLKVTDSSGVAEVEVTVPDTITEWKAGAFCLSNDTGLGLS-PTASLRAFQPFFVELT
MPYSVIRGEAFTLKATVLNYLPDCIRISVHLE-ASP-KFLAEPKAKE-------------
--------QESYCVCGNERQTVSWVVTPKSLGNVNFTVSAEA-LESSELCGNEKTVVPTY
GKKDTIIKPLLVEPEGIEKEETWTSLIRVSDTT----VSEKLHLELP-SNVIQDSARATV
SILGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPDIKSKAISYL
STG----------YQRQLNYKHRDGSYSTFG-------ENYRG-GQGNTWLTAFVLKTFS
QARKY--IFIDEAHITQALSWLSQKQKD-NGCFWSSGSLLNNAIKGGVED---EISLSAY
ITIAL-------LEMS--LPDTHPVVRNALF----CLESAWKSAKEGTHGSHVYTKALLA
YAFALAGNQERKKEILKSLEDE--GVKEDNSLHWARPQKPKV----SEGFLFKSQAPSAE
VEMTSYVLLAYLTARPAP---------------------------------TPEDLTSAT
DIVNWVTKQQNSHGGYSSTQDTVVALHALSKYAAATFTRTEKAAQVTIKSSGTFST--NF
EVNHNNRLLLQQVSLP----TVSDSYTITVTGEGNVYLQTSLKYNVPSEKGT--------
-FPFALEAETVPQACDGPKAHTSFQISLNVSY-----IGSRPVSNMAIVDVKMVSGF-IP
LKPTVKNL--E-KSEHISRTEVSNN--HVLIYLDKV-SNQTLSLSFFVV--QDIEVRDLK
PAIIKVYDYYETNEFAIAEYH-------------APCSKDP-------------------
------GNA---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|73997687|ref|XP_854220.1|	Canis familiaris
------------------------------------------------------------
---------MRRNPLPIPVLI---------------------------------------
-------------------------------------------------LFFLLLPRDAS
TTS--KPKDDLENSHKNDVFLTSPWLIQTPILHRQYLVLVPSQLYAKVPEKACVMLNDLN
ETVTVNLILEYAMQTRTLL---SDVVTKNSFY--CRPFTIPELPS---SPGLITVEVKG-
---PT--QLFIKKKKVRITKVNSLIFVQTDKPIYKPGQTVRFRVVSVDVSFHPLN---ET
LPVVYIENPKRNRIFQWQNLRLQGGLSQLSFPLSVEPTLGAYKVKL-EKE----------
SGEKIEH-------------PFEVKEYVLPKFEVQVKMPKTISFLDEEFVVSACGLYTYG
KPVSGVVTINICRKYSQ--YH---FACH--GMHSQGVCEEFSQ-Q--------ADDKGCF
TQ---LVKTKVFQLRQRGY------D--MTI-QVEAKIKEEGTEV-ELTGHGSCEITNIL
SKLKF---TKADTYYRPGLPFYGQVLLVDEKDQPMAHKTV-----VVSVDVTT-------
-------YQSSLT---------------TNEHGLVNIYIDTTN--F-TSS-----LFTVM
VTYKQNVHCFD--NWW-----LEELHNQAQHTVKH-----IFSPSKSYVHLELVAGT---
-ITCGQTQEIRAHYILNGQILKD-----------------------------------EK
ELTFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLIKARGMISRSGIH----VLSIEQGD-------------
------------LKGEFSFSFRVESDIAPAAQLLIYAILP-NGEIVADTEK-LEIENCFA
NKVNLSFSSNQSLPASHTNLEVRA-FPNSL------------------------------
----------------------CALRAVDQSVLLM--KPETELSPQSVYNLLPVKG----
IFSVGYGDLRREDS--EQC---IHAED-FIHEGI--IYTPKQ--ILDNDDIYSIF--ESA
GLYIFTN-SKIHK-PNFCQ---LPQPY----PGVP--------------------MAHAA
VNVAVQSSF----LPNSDSPAVEVK-----------------------ETVRKYFPETWI
W--DLVPVDLSGRSELAVKVPDTITEWKASALCLSEMTGLGLS-PTISLQVFQPFFLELT
LPYSVVRGEAFTLKATVFNYLSHCIRVSVQLE-ASP-DKSADLERKN-------------
--------EETPCICGNHQKTMFWAVTPKSLGKMNFTATVEA-LQSQELCGNEVPRVPEL
GQKDTVVKPLLVEPEGIEKEETFNTLLCAAETD----VPEKLSLKVP-SDVVEGSARATY
SVLGDILGSAMQNLQNLLRMPYGCGEQNMVLFVPNIYVLNYLNETRQLTETIKSKAINYL
ISG----------YQRQLNYKHSDGSYSTFG-------DHDGR-SQGNTWLTAFVLKSFA
QARSH--IFVEMSHITSSLTWLSQRQKE-NGCFQRSGSLLNNAVKGGVDD---ELTLSAY
ITIAL-------LEMP--LPVTHPLVRNALF----CLESAWGSISE-AQGSLVYTKALLA
YAFALAGNQVKRNELLKSLDKD--AVKEEDSIHWQRPGKVE-----EVTTFYQPRAPSVE
VEMTSYLLLAYLTASPAP---------------------------------SSEDLSVAS
RIVKWITKQQNANGGFSSTQDTVVALQALSKYGAATFSKREKTTVVTVKSSETFSQ--KF
EVHDANRLLLQEVRLP----EIPGEYSTTVSGSGCVYLQTSLRYNILPKKEGK-------
-VPFNLKVDTFPKNCDGVDTHRKFQIHINISY-----TGERSSSNMVIVDVKMVSGF-IP
VKSSVRKL--Q-EKPQIQRTEVSTN--HVLIYFEEL-TNQTLSFSFSVE--QDIQVDNLK
PATVKAYDYYETGDGIGACPIH--SKHRPGIAVLPGTVHPP-------------------
------QEK---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|125837226|ref|XP_001343136.	Danio rerio
---------MEVDTYSIVLRWSGPEERLFGEQRSITSNQTVTASHKPVFIRRLAPLAESK
LTGQVQSELQPRVRTSLPNWF---------------------------------------
----------------ITAVEAYKSALLIVWTSEDVFCACAGLKLLKMLLSLLLLLQWSL
TSGATDP---------------------------IYLVAVTSQAVSGSTETLCAQIHEPT
EPVSLVVTLRSDVQNMTIL---QQRSITRDFYT-CVTFKVPLVTV--ESVASINVTIRG-
---QS--TFMNKTTQILISPPQKLLFIQSDRPIYKPGQTVKFRIVSLDTKFLPYN---QV
FKTVELQDPSSNRIGQWLNQSTRSGILDLFHSISPEATQGYYMVTA-WDE----------
KNQQISH-------------QFEIKEYVLPKYEVNIDFPSVITSQDNNAPLKVCAKYTYG
KSVLGTVNVEVCGQSWY--YF---YERR--FPENDGVCNTYSK-M--------TDRTGCA
SW---MINATDFGLING-----------GNI-NVQSNVEESGTGV-TISGTTTAMFTREY
INVYF---EDTPDTYKPGMVFKGKVVVTNPQSQPMKNKPV-----VLSAYYGN-------
-------QNISLTLI-------------TDVNGTVQFSFNTSD--W-SES-----SVSLQ
ALFRGVDPTDYMALGY---------YPSSYLYLRP-----FHSKSKSFLTLMNPPKK---
-LSCNRDATVVASYIIQGSTLKTG----------------------------------QK
TLDFF-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YIVLSKGSVAHTGRL----SVNVNSKK-------------
-----------ENRGEVTFSLR-TAALAPYAQVVVYTILP-SGEAVADSVN-FPIEECLP
NKVSLKFSSPTALPGERASFSLKA-SPGSL------------------------------
----------------------CSVRAIDQSVLLL--RPEAELNADSVFGMLPVQFL---
SGYPYNVEEFELYNCP------PSWGGVRGKRSR--FYYPYY---GNRNDVYEIF--RAI
GIKIATN-SDVKA-PVDCS---YGIPF------------------------------VAA
KENEVNDVA----MPGAAFRPGVMNPN---------------------ERVRKFFPETWI
W--DLIPVGNSGSVDVAKTVPDTITTWAAGAFCTSP-VGFGLA-PSTNLTAFKPFFVSLT
LPYSVIREETFTLKASVFNYLSKCIMVKVTLA-DST-QFTAQPCRGC-------------
--------TYTQCVCAEESKTFQWTITPSVVGKVNFTVRAEA-VKTRELCGNEVVTLPDK
GKVDTVMQSVLVEVEGTKQSVTQNELICLTDRP----YNTSITLALP-KVFVKDSAKCFI
TVLGDLMGRALRNIGDLLAMPYGCGEQNMLQFAPNIYILQYLESSGQLTPEIRARAVTFL
QSG----------YQRELTYKHGDGSYSAFG-------SND---PSGNTWLTAFVMKSFG
GAKRY--IFIDQTSIDEAKNWLSQQQKT-NGCFTSVGQLIHIEMMGGVND---EVTLSAY
ITAAL-------LELG--VQISDPMVARSLV----CLKEASRNITN------TYVNALLS
YTFTLAGDGEMRLNLLSKLDNQ--ARREGAGRYWSLVNNAQQ-------------TSSVE
VEMTAYVLLALLSGPSL----------------------------------PRFGLNYSA
GIVQWLGRQQNAFGGFSSTQDTVVALQALAKYSAAVFNPEG-SIAVTVTSPSGQRN--QF
TVNRNNRLLYQEKQLT----ETTGTYKLRAEGKGCVFVQFALNYNIPPPPDA--------
-LAFNIKTNTGVCS-----KNQAFTLNVTVRY-----DGKREETNMVIINVRLLSGF-KL
DEASLQAL--K-EDPTVKRVDLDED--RVIVYLESLKKKQVKSINLRLQ--QDVLVQKLK
PAVVEVYDYYKTSMCPFISLN---------------LLKG--------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|118083298|ref|XP_423478.2|	Gallus gallus
--MAYEEVLKTNNGCQYVLLVPTVVRSNSPQTACVQFQSLSEPLSLSVVLEYSNIQTTLF
EEFVTKNDYFTCCEFKVPPATSDPLAFISFSAKGNTVNLTERRSVAIENVHNTLFIQTDK
PIYKPGQKVMFRVVTLDSQFRPVQETYPRIIIKDPEQNQIFQWLDVSSMNGIIQLSFPLI
EEPILGSYHIVVEKKSGDKEHEYFTVEEYGKQALQYVLLVPTVVRSNSPQTACVQFQSLS
EPLSLSVVLEYSNIQTTLF---EEFVTKNDYFT-CCEFKVPPATS--DPLAFISFSAKG-
---NT--VNLTERRSVAIENVHNTLFIQTDKPIYKPGQKVMFRVVTLDSQFRPVQ---ET
YPRIIIKDPEQNQIFQWLDVSSMNGIIQLSFPLIEEPILGSYHIVV-EKK----------
SGDKEHE-------------YFTVEEYVLPKFEVTTSMPRRISFFDEEIRVNVCALYTYG
QPVQGSARINVCQRHFY--NP---QC----QQSQKPRCEAVIG-L--------LENNGCL
ST---VVSTKTFQLYRS-Y---ARMY--ASF-NIETIVTENGTGI-QMKNYDYVAVSQEN
DRVMF---RNMDQYYRRGIPYFGEITVTNADGKPVPSRVV-----VLEVNGE--------
-------YQANYT---------------TDENGTAAFSLDTSN--F-FNP-----TVKLR
ATQAPDDCADF--FMW-----RNDHESEALFFVRR-----FYSRTNSFVRIEPVEEK---
-LRCGQQRMINIHYVLSRKGYRN-----------------------------------AT
HTDFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YVVMAKGKIVLSGQK----QVRIAHAP-------------
-------------WGTFAITLDVTEKLTPSARLLLYTVHP-DGEIVADSSW-IHSDVCFK
NKLQLEFSEKQAYPGSKINIHLEA-AANSY------------------------------
----------------------CALRAVDQSVFLL--QPERELSAESVYYRLHLSDL---
YGY-YYNGLNLQDDPPEEC---TPVKT-TFFDGL--YYEPVN--VSHDGDVYRIF--REM
GLKVFTN-STLRK-PVLCN---E-DKL-----DWE--------------------ENRIY
FEHGASGGS----AFGKEFSKITAAGV----V----------------NTVRKYFPETWI
W--DLVHTDSTGEANIFYTVPDTITEWKASAFCLQDDAGFGIS-SPVSLTAFQPFFVDLA
LPYSVIRGEKINLIANIFNYLDKCIQISAILA-ESS-DYKAEVLSPE-------------
--------GNTARVCANERKTYIWAVSPLSLGEVKFTITAEA-KLNTKGAKNSTPPEEES
IRTDTLTQTLLVEPEGIKKELTQSSLICTKGTT----VSEPVLLSLP-RNVVQGSARVYF
SVIGDILGTALRNMENLLHMPYGCGEQNMALFTPNIYVLDYLNKTGQLTEEIRVKSTGYL
TTG----------YQKQLSYKHQDGSYSSFG-------TRD---KEGNVWLTAFVYKSFA
QARRY--IYVDENVQSQTLIWLARKQKS-DGCFENAESHFNNALKGGEEG---EYSLTAY
IVAAL-------LEAG--HSVQHPVVWNGMN----CLETAFSNGVH-----NLYNHALFA
YVYGLADKQERYQYFLEKLDKR--ATRDGGSVYWQRENKPPA----EHFPAFYSRAPSAE
IEMTSYVLLALLNKAEL----------------------------------TPDDLSYIS
RIVYWLVKQQNPYGGFSSSQDTVVAIQALAQYGYLTFSKES-HNTVKVNFMEIPKK--AF
QVNDENRFLLQQTSLP----TVLGNYSVEVYGTGCVYMQTTLKYNIHLPKKA--------
-AGFFLSVEPANVSCTS-NFPLKFDLVFSASY-----TGNRNVSNMAIIDVKMLSGF-IS
DRSSLKKL--QYQASVVDHVDIKND--HVFFYLQKL-SQKEVSFSFSVE--QSLPVSDIK
PAPVHIYDYYET------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|115712705|ref|XP_784747.2|	Strongylocentrotus purpuratus
-------------------------MMQSGSVVLLVLFGVILGI----------------
-------NAQERPPFPPPDPV---------------------------------------
------------------------------------------------LPVVPTLTTPTV
YPG-------------------------------QYIILAANTIRPGMPLTLSVTIFETQ
GGAPVSLEAAIIRDNVVAV---STTAILQTGTN-QVTLQIPVAAS---AAGEYSLRVVG-
--TGG--LTINETRSLFFNIDHFSIFVQSDKAIYKPGQTVRYRVLAVYPDLKPY------
--------------------------------------VGPFTLTV--------------
SGQIKEY-------------TIKIDEYV----------PPWMDASHDQVQVTVTAKYTFG
KPVEGTVSLGAKLRYYN-----------------REIHKRIQV-D--------NNGKAET
NF----TSTELLGLKRQTYNHNPTWYNNEQL-VFTANMTETLTGITQQADEAALSYHSFP
IKIVF-QDSISRSNYKPGLPYHVYLIVSHQDGTPLTEEERLR---GVELRDCRERC----
-------YGDNASWNLQRITI-------EPQTGVAEAFIASRS----SDF-----SIQLS
AEYKGVIPKRFTFPGYSRNGIAVPLPAGTYITAETKYLDKAASDSNTYIQVSPDNAE---
ALMIGSTASFTVQSTMAPGKFTYQIVSRGNILESETISGVTGTEYVITKQITADMSPKSK
LIVYFLTDAGEVVLDSLEFVVNVVFANPVTASFSKIEAEPGTSVSFDVDTTPGAFVGVLA
IDKSVLLQADGNDITHNQVLESVGRFDTTADGSGGFNPFFDFAFCFFPYPTNGNNAGSIL
KAEYKGVIPKRFTFPGYSRNGIAVTLPAGTYITAETKYLDKAASDSNTYIQVSPDNAETL
TIGSTASFTVQSTIAPGKFTYQIVSRGNILESETI----SGVTGTE--------------
----------------YVITKQITADMSPKSKLIVYFLTD-AGEVVLDSLE-FVVNVVFA
NPVTASFSKIEAEPGTSVSFDVDT-TPGAFVGVLAIDKSVLLLADGNDITHNQESFVGVL
AIDKSVLLQADGNDITHNQESFVGVLAIDKSVLLL--ADSNDITHNQVLESVGRFDTTA-
DGSGGFNPFFDFAF----------------------CFFPYP---TNGNNAGSIL--KNA
GIIYITDGNVVYV-EEPFW---EYDIVAFAQFDGGVAQGIIYITDGNVVYVEEPWFRQEF
FPVAAAGGF----GGGARADMVPNAGA----------GRQNEAGVVPEKKIRKEFPETWL
W--VDTEADSAGRVSIQTNFPDTITSWVGTAISMDAQAGLGVTQNAAKATVFKNFFVSLN
LPYSVIRGEKFVLEANVFNYLKQDVRATVQLQ-SSM-DYYIIQGDKQ----------MST
PV------SKTVTVPSNKTATVNFAIEPTKNGMIELVVTATA-----------------G
GEQDGVRRLLLVEPEGVAQEYVVSDLVDFSNAAA---YSKKFSIDLPTQDLVPDSVRAVI
TATGDILGPTMNNLDQLLRMPSGCGEQTMIGFAPDVFIYKYLTETGQGNPTIEQKALNYM
KKG----------YQRELTYQHEDGSFSAWG-------GGSG--DDGSTFLTAFVVRSFL
QAAPY--IYIDPAKMNQAITFLINHQND-NGSFMKSGRIVDQIIDGGISS---AETLTAY
CAIAMDQVRTSDILSDTTKSTANTALTNAMN----YLVSRYTVIQE-----DKYAMAIVT
YALALGGSPST-PQFLTRLNELQTVEDEGRLKYWTDQDEQTTPASDEFYYRVWRGPPSAA
IEMTGYGMLAYL---------------------------------------ARNDVVGSI
PVAGWLSQQRNSLGGYSSTQDTVIALLALTTYAERLTGGDK-NMNLAITTTADPAYNQAF
SINTQNSIVLQQFELP----VDSGNVTVEGRGIGSFLLSFILHYNMLEVRSS--------
-DVFDVTITILGS------DTNSLDLRACGRY-----TGNGEGTGMSIMDIGIPSGFYVE
EDPLLEAI--K-THEFATKHEITGK--SVVIYLNEIPSMMETCISIQAR--RSNTVAATK
PSIVKVYRYYTPEEQSVQSYS---ASALSATDICTMC---P-------------------
------DCCNDGGGSGGAVPSTATSTLLLLTLTIFSIVGALVM-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|6009727|dbj|BAA85038.1|	Cyprinus carpio
------MDL---------------------------------------------------
-------NVSCCWKGL----L---------------------------------------
------------------------------------------------LFSLLLVCVNGQ
TSG---P---------------------------YFMVTFPAVIESGSEAKLCASLLKPN
ESLVMNIYLVHGDQSTLLL----QEKAEEEFHR-CFNFKAPLVEA--ESVQTMKVELQG-
---ES--FKMTEERKVIFRSYHPLTFIQTDKPIYIPGQTVNFRVVTMDTHFAPLD---QQ
YGSVVLEDSQGNRIGQWTNVSSTRWILQRSYELNPEARQGVYRLKT-YI-----------
GERMISH-------------DFEVKKYVLPKYEVTVKRPNEVSVDEEELSIEVCGKYTYG
QPVPGKSWVKVCRNILP--YL------Q--ARDRNPLCLEETT-E--------IKKTGCA
IH-TIDVSVFLNSTLKSSL------Q--DSL-RVEAMVTEEGTEI-TMTKSETISLTYEI
GKVTL---TDLPKTYEHGSVIEGKIKLSNFKDAPIQNKEV-----YLFEVVNWSSK----
-------LLLNLT---------------TDSDGLASFSLNTSS--L-PEK-----DINLM
ASVYTEFHH----RGY-----KTPYFSTDRKTVQLLRPVTPYTPTLSELIIENIEQP---
-LKCDAEFTVTIKYYFIGETVEDF----------------------------------KT
DIV---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YMVLSRGLIVHHGYE----KVEVKSSN-------------
----------GAANGTVSFKLSVGADLAPAVQILTYCVLP-SENVAAGSTQ-FDVEKCFS
NKVSLQFSPAKAVPGEKNTLQLSA-QPGSL------------------------------
----------------------CGLSAVDQSVLIL--ESGKRLDTDKIFNLLPVQSV---
SSYPYTVEDQQECL----------------------HVRPRR--ALSTDNAYEAL--KRV
GLKMATN-LAVRV-PQCLS---YRGLTYHRYSDIV--------------------MYRQH
APVSVLRMS----SLEDADFATSSRDS-------------------PAVTIRTVFPETWI
W--ELAEVGDSGSAQVPVTVPDTITSWETEAFCMSS-KGLGLA-PPAQLTVFQPFFLELS
LPYSIIRGEIFELKATVFNYLSKCIMVKVTPA-PSS-DYTLKASSDD-------------
--------QYSSCLCANERKTFKWILTPSVLGVLNITVSAEA-ESSQTVCDNEIVSVPER
GRIDTVTRNLLVQAEGTEKTETYSWLLCPKVDS----LSEEVDLNLP-KDVIEGSARSSV
SVIGDILGRALRNLHGLLQMPYGCGEQNMAVLSPNIYILQYLENTEQLTSAIRERATGFL
KSG----------YQRQLNYKHSDGAYSTFG-------YGD-----GNTWLTAFVLRSFG
KAQKY--IFIDPQIIQSAKEWLISRRDS-DGCFIQQGRLFNNRMKGGVND---NVTMTAY
ITASL-------LELE--TPVTDPVVSKGLS----CLRSVIKDVKN------TYTTALLA
YTFSLAKDTDTRQQLFKKLEDV--AISGGSLLHWSQSASADD-------------SDSLA
VEISSYVLLAVLTADSL----------------------------------TTADLGFAN
RIVSWLVKQQNAYGGFSSTQDTVVALQALSLYATKVFNSDG-SSTVTVQSVGDTHH---F
DVNQDNKLLYQEKQLQ----NVPAKYSIEVKGSTCVSVQVAQFYNIPTPTEA--------
-KTLSIDAKIEEDCK---TLGQNFILNFTVKY-----DGLQERTNMVIVDIKLLSGF-TA
DTTMLGTSSGK-YAPLVERVDAKDD--HVIVYLKEIPNNIPMNYQIQMK--QVLPVKNLK
PAVVKVYDYYQTSDQSETEYS-------------FHCQ----------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|114643427|ref|XP_001139559.	Pan troglodytes
------------------------------------------------------------
---------MGKNKLLHPSLV---------------------------------------
------------------------------------------------LLLLVLLPTDAS
VSG--KP---------------------------QYMVLVPSLLHAETTEKGCVLLSYLN
ETVTVSASLESVRGNRSLF---TDLEAENDVLH-CVAFAVPKSSS-NEEVMFLTVQVKG-
---PT--QEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLN---EL
IPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVV-QKK----------
SGGRTEH-------------PFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYG
KPVPGHVTVSICRKYSD--A----SDCH--GEDSQAFCEKFSG-Q--------LNSHGCF
YQ---QVKTKVFQLKRKEY------E--MKL-HTEAQIQEEGTVV-ELTGRQSSEITRTI
TKLSF---VKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVI-----FIRGNEAN-------
-------YYSNAT---------------TDEHGLVQFSINTTN--V-MGT-----SLTVR
VNYKDRSPCYG--YQW-----VSEEHEEAHHTAYL-----VFSPSKSFVHLEPMSHE---
-LPCGQTQTVQAHYILNGGALQG-----------------------------------LE
KLSFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLIMAKGGIVRTGTH----GLLVKQED-------------
------------MKGHFSISIPVKSDIAPVARLLIYAVLP-TGDVIGDSAK-YDVENCLA
NKVDLSFSPSQSLPASHAHLRVSA-APQSV------------------------------
----------------------CALRAVDQSVLLM--KPDAELSASSVYNLLPEKDL---
TGFPGPLN--DQDD--EDC---INRHN-VYINGI--TYTPVS--STNEKDMYSFL--EDM
GLKAFTN-SKIRK-PKMCP---QLQQYEMHGPEGL---------------------RVGF
YESDVMGRG----HARLVHVEEPH-----------------------TETVRKYFPETWI
W--DLVVVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGIS-STASLRAFQPFFVELT
MPYSVIRGEAFTLKATVLNYLPKCIWVSVQLE-ASP-AFLAVPVEKE-------------
--------QAPHCICANGRQTVSWAITPKSLGNVNFTVSAEA-LESQELCGTEVPSVPEH
GKKDTVIKPLLVEPEGLEKETTFNSLLCPSGGE----VSEELSLKLP-PNVVEESARASV
SVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYL
NTG----------YQRQLNYKHYDGSYSTFG-------ERYGR-NQGNTWLTAFVLKTFA
QARAY--IFIDEAHITQALIWLSQRQKD-NGCFRSSGSLLNNAIKGGVED---EVTLSAY
ITIAL-------LEIP--LTVTHPVVRNALF----CLESAWKTAQEGDHGSHVYTKALLA
YAFALAGNQDKRKEVLKSLNEE--AVKKDNSVHWERPQKPKA----PVGHFYEPQAPSAE
VEMTSYVLLAYLTAQPAP---------------------------------TSEDLTSAT
KIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTKTGKAAQVTIQSSGTFSS--KF
QVDNNNRLLLQQVSLP----ELPGEYSMKVTGEGCVYLQTSLKYNILPEKEE--------
-FPFALGVQTLPQTCDEPKAHTSFQISLSVSY-----TGSRSASNMAIVDVKMVSGF-IP
LKPTVKML--E-RSNHVSRTEVSSN--HVLIYLDKV-SNQTLSLFFTVL--QDVPVRDLK
PAIVKVYDYYETDEFAIAEYN-------------APCSKGK-------------------
PLTLLQKAVRAPSACPPNLLLHKALGKYLSKTSNYSHCTLL-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|157119257|ref|XP_001653325.	Aedes aegypti
------------------------------------------------------------
-----------------MHHM---------------------------------------
------------------------------------------------------------
----------------------------------YYTVVGSKLLRPNSEYHVSVSNLNVR
EPLRFRITLNNTRTGTPLAS--EDLSLGQGESR-LVPFSIGDITE-----GDYSLTAEG-
--LSG--FIFKNESSLTFQSKSFSVFVQTDKAVYKPGDTVRFRVLVLDPNTKPLQ--KID
TVKVHITDGKNNRIKQWNDAKLVKGVFESELALSSAPVLGNWKINV-EA-----------
LGTKKTQ-------------EFEVDEYVLPKFEVSVESPGITTLKDGKVKAIVRAKYTYG
KSVKGEATVSAYPDFNF--HYV--------QPFERDVITRKTV-P--------IDGKGSV
EF---DLRDEIK--LQGDY------T--RNI-VIEAVVEEELTGR-KQNSSSKVKIYDRA
YNMEL---VKSSEKFKPGLPFTAWLKATFQDGAPLQDDTN-----SVKVTQEFGWPNQNT
-------TEHTYK---------------LDKNGMAKLIIDTET----SSD-----SISFR
AEYLGA-------TFY-----LGSISQG-------------WVKYSAYVRAKVLTET---
-PTINKDVTVDVSS--------------------------------------------TV
PMKYFN------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YQVLGRGDVLIGGTI----AVPDRMSH-------------
-----------------TFRFPASFAMVPRARLLVYFIHS-DGQMISDFAE-IEFASELQ
NFV-MQLSKTESKPGQDVDITIST-NPDSY------------------------------
----------------------VGLLGVDQSVLLL--KSGNDLTTGKVFDDLKTYEE---
AVYLQYRRK---------------------------RFAPWR--------RFNYYDDFNV
SILLFNYSSDTSRLPPITY---KVQRAPDGTPLYT--------------------VIEKN
PRFLPVHEF----KTNTRPPLAGPFAF---------SRIPRPHRDVPRVFLSREIADTWL
F--ENAYSGFSGEKTITKKVPDTITSWMITGFSVSPVYGLGLTRQPRKLNVFLPFFVSTN
LPYSVKRGEVVSIPIVVFNYMDSDQTAEVTFH-NTEQEFEFADVENE---------VHEN
PK-LELFRKKTVQVASNTGKTIPFMIKPSKLGHITIKVTATT---------------QLA
G--DGVERQLLVEPEGLPQYVNKASFVDLRATPE---VNNNFTVEIP-KNAVPDSTRIEI
AVIGDVLGSTIQNLDSLIRMPYGCGEQNMLNFVPNIVVLDYLKNTNQLTASIEDKAKKYM
ESG----------YQRELTYMHDDGSFSAFG-------KSD---PKGSTWLTAFVARSFK
QAADH--ISVDEKIIDKSLEWLSDQQSS-NGSFPEVGKVSHTDMQGGSGQ---GIALTAY
TLIAF-------LENKNLIPKYTNVINKALD----YIVRNTEGLDD------NYALAIAA
YALQLADHSAK-DFTLSQLDTK--ATTDEDQKWWNKPIPEAD----KKNPW-YSKPNSVN
VEMSAYGMLAFM---------------------------------------EAGLDSDAL
PIMKWLISQRNDKGGFQSTQDTVVGLQALAKLAAKISSKNN-DVTIVVTYNENQQK--EM
KINSENNMILQKFELP----SSAKDIDIKATGRGFAVVSLGYKYNMNVTGEW--------
-PRFVLDPQVNKNS-----NQDYLHLTVCTNFVP---TAGQNKSNMAVMEVGFPSGF-TA
DSDTLPSL--E-NTEYIKKVELKDGDTVVVMYFDSL-DRNELCPTVSAF--RTHKVAKQK
PAPVVIYDYYDNSRIARQFYN---GPA---AGLCDIC-ENE-------------------
------DCGN---SCSIKSQKQRS-------PKEEATVMAK-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------SGAVGITIGLQLIVAAL
L-------------------------VRLFN---
>gi|45259535|dbj|BAD12264.1|	Eptatretus burgeri
---------------------------MMRFPVVITLLGIALTS----------------
-------ARQGVATTSEPTPL---------------------------------------
------------------------------------------------LPPSLLPPSPVI
V---------------------------------NYLIMIPQPLRPNKVLSAGVSLYGED
EGLPITLKFNLSRNDRSLFVH-SVEAAVGEATT-VTLPPVPSDCD---FDGTYKMQVQAF
TGEGG--LVFENTTTLQFQKKFQMTFIQTDKATYKPGHTVKLRVISIKPNMHADH----S
HLDIIIQDSSENRIQQWLSEPNPIGVVSKEFILSDQPPLGDWTIQVTHLD----------
SQSTSSK-------------SFTVAEYVLPKFEVKLQVPSFIVRNDFAVVGTATAKYTYA
KVVRGVANITLSSAIWN--PCREGGTRKRPNPGMETLTITYNGIK--------FNGSVDF
AF----TNDEILEMMEGDE------P--NNL-KIRVDVREDLTGI-VRRAEQSIRIAHNR
YQISF---INSPEKFKPGFNYTGYVQVTLNDGTPLLERDR-SIPMQLSVKQSNESGTLEI
-------TDETFL---------------LHDSGIQSVQFTSLP----EAT-----NVEIK
GKFGKQNI-----HQY-----LNVE---------------SRSLSGGFIHVTTNTAQ---
-AKAGIPISFTINGL-------------------------------------------NL
PEKIS-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YQVMARGNMVEFGQV-------------------------
--------------SSKNFQLMPTSSWAPMAKLLLFYVRP-DGEVINEVLG-LSVEGVFE
NMVDLNWSTLQAAPAEGVDLTVSTGEAEAY------------------------------
----------------------VGLLVVDKSVLLL--KEGNDLTNERVTTELSQFS----
QGRPP-----------------------TFYRGVPRFWFPSS------QDTESIF--SEA
GVAFLTN-LYVHD----IP---FYHTR-----YYA--------------------VAHSA
MLESAPVAM----AYSHKDSPVGFTGS---------------------THVRTLFPETWI
W--TDAITGPNGSVSISATVPDTITSWVASAFSLGPKLGLGIA-ETQQLQAFQPFFISLK
LPYSVVRGESFLLMVTVFNYLSEEQKVFVTLQ-ASD-GFHLISGKDEKERKDLAKRATDK
PM------QRSIMVPSNDGVTIAFPLSPRRLGYIPISVKAHS---------------TQA
A--DAITDHILVKAEGLPRTYSKAFLIDHKEGQV---TQEQLQFTFP-NDVVEGSETAII
SVVGDIMGPSIEGLDKLVQMPYGCGEQNMINFAPNIYVLQYFEAIKHPAANIRRKALSYM
NSG----------YQRQLTYQHRDGSFSAFG-------EMD---ERGSTWLSAFVLKCFA
QAQAH--MYIDKNLMKKTLNWLQSQRTP-DGDYQELGHLLDSSMLGASSG---SVALTAY
VVTSL-------MSSPK-LEVEASNMLITMN----YLEREFEKGIE-----DSRVLALVT
YALIL-GNSSKANSALDKLNSL--ATHEGGKMFWKSASV-------EEPKWHWQ-PSASG
VETAAYALLANF---------------------------------------KLHRAEEGV
PIMRWLGQQRNHLGGFVSTQDTVVALEAMSEFAAQMSAGRG-HLDLSINTTSMSAPA-TF
AIDQNNSLVLQKSELAVSKTSKDLTVAVETKGKGSALVQLNVLYNVDPGKKTETDDSAQN
-EVFNLDVSLYDGS----KDKNHISVDICTS------RKDKPQSGMVLLEVNMLSGF-SA
SKD----F--Q-KPDSVKRMEVENN--KVSLYFDEV-VQNTTCVMIPAE--RINSVGNTK
DATVMIYDYYQPTQRTEVTYK---STVMADQSVCDFCKSNC-------------------
-----VGCG---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|66512585|ref|XP_392454.2|	Apis mellifera
------------------------------------------------------------
-----------MNKLVFLVLF---------------------------------------
------------------------------------------------ICSVTFLHCCDA
VSNVNR----------------------------GYVFTAPKKLYAGEIETGCLSLHNLE
LPAHVHLELVFSFLEGQEVLASTSAVVKTGTET-CLQLAVPSPIY---RTAILRLKIKF-
DKYPD--YVIKSETDVEIEHDSLLTFVETDKPTYKPGQDVKIRILMLMHDLKPWQ---KS
IPEVWIENPSFVKVKQWTNVSTENGMAQLTFPLSPEPSLGSWHIKVMKKK----------
PYPNLIH-----------STTFKVEKYVLPKFQMTINSPQYILANVENVTWNICVKYSYG
KPVKGNLLLKLTPQTPS--WT---------RLPNLPAIRYETK-L--------DKGDGCT
DF---VLSGSVLGLAHWKM-----DP--NNI-VLIAEFTEAGTGI-VETTISRTVVLHEA
LKLEY--EHYTPKYFKFGLPYHGKLRVLRYDDTPAPNEKI-----QICLKVRGKIEWEKD
VV-----DCRDFR---------------SSTDGFVDFVVPPQHKNIVLLS-----FVATA
VDYPTTYYSPEQ-RWR-----VFMNQPSTSITVNP-----WYSPSDSYLTVARGNQP---
-IVCGEKYSFNVMYTTSSNM--------------------------------------NE
TISFH-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YSINSKGSILIYGHV----KHKPNRDTILNYFEFHNLLGT
IESSANKTNKEAIVHRFPLSVKVTPSMAPVSELLLYYVRS-DGEIVATTYT-IEVGHCFE
NKVKSTWHTDAQIPGSPTQYHVEA-APRSL------------------------------
----------------------CAISAVDKSTLFLSKSESNLMSSTQTFDALKRFHPTPK
FYFPWENSRCKSAIGPEEMKEEINHLPQFLRSKRQTITYSKR---VNYVDAVQAF--VDF
GVIVMSD-LVLET-RPCPW---LFMEYTALSRQYI--------------------STNEY
MSMKDNSEF----AVAAAAMDSGIGYV--------------DQNQAQMATLRSYFPETWL
W--ELVPIGEEGKITIERTLPHTITDWVGYTTCISPTHGLGIA-PPTTITAFQSFFLDYN
LPYSIKRGEIMRFKVSLFNYMHHSLPVKIKLE-EME-KIDLHLSEPT-------------
---------ASFCVKPRDNIVHEYILKPRVIGEVNITVTAFVDIDYPEPCGSE--TVIFT
Q--DVIVKPILILPEGFPVEETKSALICPKDSSDD--SSFMWELTLP-KDAVPDSGRAYL
NLIGDILGPALENLDKLIKLPKGCGEQNMILFVPNNHVIKYLDAMRINKPDLRAKAIRNM
EKG----------YQRELKYRFMDGSYSAFE-------E-----GESSIWLTAFVLKSFA
QAASL--IHIDKYVLESSVSWITMNQLE-DGCFPVIGTVFHKSMKGGLQEHGSSSALTAY
ILISL-------LESG--VPLSPSVVNDAQK----CLEKGMNNDD-------LYTTVLTT
YVLALLEHPKA-NSSMKSLMNR--ATRYKNLIWWEDKSKPSI---------------GLS
IEMTAYVILTLLKL-------------------------------------GEENLSEAL
KAVRWISKQRNSEGGFTSTQDTILGLEALTKYAMIVHHNNITDLSVLVTASKEVDD--VY
KLQDENRVILKQIRLP----ILPTIVEIFAQGEGCVLIQSNLKYNVASSTGS--------
-DAFDLSAEVRSVGYG--NECSLQEITICSRY-----KMADEESNMALLEVGIISGY-VP
DRASLHSL--LDPSSKVKLFEEDQD--IVTIYFNKL-TGQKTCISFRII--QEYFIDHLK
PANIKLYDYYQQELTVSTNYK-----------IPSICSSAEPVDEQLTTPNEMIIMKQLS
FDESPMNSSFVVNNAELAIPDGMEGPIPVYVKLNTYDYKTE-------------------
------------------------------------------------------------
-------AATTTNGLPDLTSTFVTEDQTVPTVQTEDEEPIRIDTDNPSITNPLMKEVLRI
VKILKINETNVPSPTRINQSCPICMDVLPSNISDIYCSANSAVKVAIRRFRKVRLLLDLH
ISREVKRLRAMIEFTLSPNCSCSPLDNPGSFALIINKDNDFLTSGNQKQTLNDSFYIYGL
PLVSGVPCKLAEIRASCLNEDNIQCTYEDPPAYG
>gi|124481722|gb|AAI33194.1|	Xenopus laevis
------------------------------------------------------------
-----------ATNTMLLRLL---------------------------------------
------------------------------------------------HVGLLLLQLSGT
PEA--KL---------------------------QYAVIFPAEMVSPHSEQACVHLEGAN
GESKIQLTLQMAKSNTTVI---EKTSEQKSYFR-CVSFEVPPPSEENEEVATMQVSIQS-
---GG--ETISNSSKVLVKKARTSIFVQTDKAIYKPGQTVRFRVVSLKENLQPEE---SQ
VPTIELQDPGKNRIGQWLNVSLQQGIAELSLPLSSEPPLGEYSIHV--------------
--KNTVH-------------VFSVEEYVLPRFEVTLQLPKVVVVVTGQFPVKICARYTYG
KPVQGTYKVDVCRKHYS--YR---RAFG--NDKGRDLCADFSG-K--------LDQSGCS
TF---DVKSSNYNLLSSEW------Q--MNI-EGAGWITEDGTGI-QISATDKSQISYDL
TSVTF---LDADDTYKPGIPYIGTVKVVDASDTPIPKHPV-----YLIDTDGI-------
-------VNMTLM---------------TDKNGLAPFKLDNTADWK-ATV-----SLTAK
TQVKEPLMQYQ--YGM-----MFPRHGLAMLRLNR-----FYSRSKSFLKLHSQNGE---
-FLCEGQQEVQVEYLIKRTELGEE----------------------------------AK
HLELH-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLAVSKGAIKESDVL----EVPINNDG-------------
----------EVLRGEVSIKLKLSVDVSPTLRVLTYVLLP-GGEMVADAAK-FKLQKCFR
NKVSVGFSPDEVLPGSDVSLQVQA-AAGSL------------------------------
----------------------CGLRVVDKSVVLM--KPDQELTADKIRGLFPVNDF---
GNYDYRIQEAEDHCPFRPFLPWRPFN--RISRSI--IYPPWH--MPEEADVYGLF--KKV
QLKIITS-ADIKK-PVVCQ---HYDFLRPGLPGLP------------------GPTGDRM
IAFASPGIS----AAGSIPNQLPEAES------------------AAVEIIRTYFPETWI
W--ELASVGESGTEELHRAVPDTITDWNAGAFCMGP-SGFGIS-SPTSLRVFQPFFVEIT
LPYSVVRGESFALKATVFNYLKQCIKVQTALE-PSQ-ELEEEPCPDC-------------
--------QYSSCVCAEESKTFYWNVKASNLGEVNVTVKTVA-LDTQDLCNNEIPIVPKQ
GRSDTVIKPLLVQPGGVLEEKAHSSLLCCQAGDDH-PKTEEISLKVP-ENILKDSERAYV
TVLGDLMGTAMQNLDRLLAMPYGCGEQNMVLFAPNIFILQYLEKTHQLSPEIQSKAKRFL
ESG----------LQRQLTYKRDDGSYSAFG-------QRD---KEGNTWLTAFVVKSFS
KARPY--IFIDESHLKHSFTWLKNNQHE-SGWFQSVGRLFNNAMKGGIDD---ETSLSAY
VTMAL-------LEAG--LSVQDPMVEGALS----WLRKAAKDVSS------IYTQALLA
YTFTLSGDTELREMLLAKLDEK--AVKSEGQLHWERKPAAA-----PSDLPYWYQAPSAE
VELTSYVLLTLLSG-------------------------------------LKKDLGKAS
EIVNWLSKQQNPYGGFSSTQDTVVALQALAKYAEATFTDKG-DVTVTVSSKTGFHQ--QF
HVDQNNRLLLQKSSLS----DIPGDYSLSASGSGCVYVQSVLRYNIPPPRSD--------
-ATFSVQVKTLPDKCPQ-DLLKFMTLGITVKY-----TGTREKSNMAVIECKMLSGF-IP
SKGSIRDL--E-KSKAIKRSEIQTD--MVTLYLDEL-GHEPLHLAFTVE--QDIVVKNLK
PATVKVYDYYETGEEAVAEYN-------------SPCSSDG-------------------
------EKGNTK------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|74096015|ref|NP_001027688.1	Ciona intestinalis
------------------------------------------------------------
--------MNLRWRPACSLGT---------------------------------------
------------------------------------------------IYLLATLSSLAT
ASN-------------------------------VYNIYFPKHIRPGFNISFTAAIIDNP
NTVQIHTAFRSMDNSFHVDS--TDSVNSGSSSR-ISMNGLPIHYS---GSHGFELNITGT
DLVTGAQLFFNSSTDFQFQAKSISILIQTDKAIYQPGHTVKFRAIALKPDLKPLQ----G
NISYTFKDPRGNVVMLEPEVPLNHGVAGGQFSLTKDAVAGMWKVEF-MA-----------
EGFKESL-------------SVEVKRYKLPKFKVEVKAPSYIHPQSTGLTIKLDAKYTFG
KGVQGTGLLEVVGGYQYPVYHGFGGRFAPRPPTQNKITRRYPN----------FDGTVEL
LITNDEIREELGW--NGAS------E--SII-TVTGSVTEALTRE-AFNDTQRIDAKTTN
VKVET---LVKPLTIKPGLKYSAYIQITEVDGKPLPEDDRLANNLLLNIEYRYPRGEPEP
GTNTTVSTWYAYRWEETRVFV-------IPPSGIVKVTIDAPSD---TFT-----SINFR
PYTNATMS-----QRW-----ALQWTAER-----------ADSPSNSYLQITTEENS---
-VVPGNMATVTIRT--------------------------------------------TE
AVSEFT------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------ILIISRGEILSERKF----QTLSGVPE-------------
--------------NSHLFEFSVEYDMIPGVQVLASYVRD-DGEIVADYIK-LTVTAELE
NQVSITSSSTNIDAGEDVSIRVQTSSSGAY------------------------------
----------------------VGARAIDQSVLLL--KSGNDVSQERIVTDLNKYSVTQE
LNHMW-------------------------------RWWWWYPTPSGASDASDVF--RKA
GILVFTDALVYQK-----P---EASIYPFRPIAFS--------------------LNGGF
AERNIIATA----AVDTSTPATPTRT-------------------------RTLFPETWL
W--DEQISGADGSATFNTTAPDTITSWIFSAFSVSDQHGLGVS-EQHKVTVFRNFFITLN
LPVRVIRGELIIVQAIVFNYLSTEVDAVLTLT-ESN-KFVLLRPGNN---------SAAV
GF------SRRITIPASGSVSVKFPIRMGTLGEIPITMTAIS---------------EIA
S--DALTRKVFVQPEGITQCTSGSVLFQRMDASAP-PDVESLNIQIP-AGIVPGSEKVKL
LVYGDILGSTMNNLGSLLRTPSGCGEQNMLGFAPDVFVTLYLHSAGKLDAATRAKAFKHF
QTG----------YSNELNYKHRDGSFSAFG-------EGD---ASGSTWLTAFAAKCFM
FARELRPTLVSASVIDQALTFLINQQNT-TGTFREPGRVSHKAMQGGVDS---PITMTAY
VLITL-------KETN--YAVKNRAVQEAAENARIYLENHLTSISD-----NKYALAIVT
YALHVAGSSRA-NEALLALEAL--ATVQGGFKFWHDNSESPDSYS-SRWRPYYYNPPTND
IEMSAYALLTYV---------------------------------------RRNDLNAGI
PVMKWLASKRSSLGGYSGTQDTVIAIQALSKVAGLLVGNTQ-NLQISASHSNDPFTA-SY
NINRENSIVFNSVNVP----AVDGTVQVTATGVGVAVAQISVCYNTPNQPYEI-------
-EPFQCTNTVVST------ALKKAKVNWCCSL-----RPGDNATGMFLMEVNLPSGY-TV
NIDNERT-----RNPSAKLVEIDGN--GVNVYYDELAPGRSVCADIELL--NLGNVGGSK
ARKVAASDYYQPKERVEALYQ---VDEA--PVVCDSCSTEDIAVCSVCADCVGCPGPAFT
QWSEWSDCA----FCGRSTSFRTRECRSPFSDNLAGHVCGGVDRESRRCVATFPCPDTFD
GLWFNMPRNFPSSNSVPFYAHQCRMERGSRQIREQIPGIALSGSQYLTCNNYDVNPNNNY
TFSILVKPNRFRSSGPTTIFSYGMEHNYARAHLEKVWWRSELRFKVRSDTGMREVRGVSS
NLLRTDQWNHIVVAVPSGDGDDIRMFVNGNAVGSTKSFTTRYFGKHGRNRFFLGQNTRGN
AWARGYFQGGLAAVGTWRSVLTDQQITALYEAYRPAIESSDPLSVKLLRHFAVQQLLLCF
QSPATIEDLYSRSAAPVTCPTAPISPLMPFLPIL
>gi|46812315|gb|AAT02228.1|	Homo sapiens
----------------------MGLLMSRVQYRLESIWSPPAPS----------------
------FCNMGKNKLLHPSLV---------------------------------------
------------------------------------------------LLLLVLLPTDAS
VSG--KP---------------------------QYMVLVPSLLHTETTEKGCVLLSYLN
ETVTVSASLESVRGNRSLF---TDLEAENVVLH-CVAFAVPKSSS-NEEVMFLTVQVKG-
---PT--QEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLN---EL
IPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVV-QKK----------
SGGRTEH-------------PFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYG
KPVPGHVTVSICRKYSD--A----SDCH--GEDSQAFCEKFSG-Q--------LNSHGCF
YQ---QVKTKVFQLKRKEY------E--MKL-HTEAQIQEEGTVV-ELTGRQSSEITRTI
TKLSF---VKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVI-----FIRGNEAN-------
-------YYSNAT---------------TDEHGLVQFSINTTN--V-MGT-----SLTVR
VNYKDRSPCYG--YQW-----VSEEHEEAHHTAYL-----VFSPSKSFVHLEPMSHE---
-LPCGHTQTVQAHYILNGGTLLG-----------------------------------LK
KLSFY-------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YLIMAKGGIVRTGTH----GLLVKQED-------------
------------MKGHFSISIPVKSDIAPVARLLIYAVLP-TGDVIGDSAK-YDVENCLA
NKVDLSFSPSQSLPASHAHLRVTA-APQSV------------------------------
----------------------CALRAVDQSVLLM--KPDAELSASSVYNLLPEKDL---
TGFPGPLN--DQDD--EDC---INRHN-VYINGI--TYTPVS--STNEKDMYSFL--EDM
GLKAFTN-SKIRK-PKMCP---QLQQYEMHGPEGL---------------------RVGF
YESDVMGRG----HARLVHVEEPH-----------------------TETVRKYFPETWI
W--DLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGIS-STASLRAFQPFFVELT
MPYSVIRGEAFTLKATVLNYLPKCIRVSVQLE-ASP-AFLAVPVEKE-------------
--------QAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEA-LESQELCGTEVPSVPEH
GRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGE----VSEELSLKLP-PNVVEESARASV
SVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEVKSKAIGYL
NTG----------YQRQLNYKHYDGSYSTFG-------ERYGR-NQGNTWLTAFVLKTFA
QARAY--IFIDEAHITQALIWLSQRQKD-NGCFRSSGSLLNNAIKGGVED---EVTLSAY
ITIAL-------LEIP--LTVTHPVVRNALF----CLESAWKTAQEGDHGSHVYTKALLA
YAFALAGNQDKRKEVLKSLNEE--AVKKDNSVHWERPQKPKA----PVGHFYEPQAPSAE
VEMTSYVLLAYLTAQPAP---------------------------------TSEDLTSAT
NIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSS--KF
QVDNNNRLLLQQVSLP----ELPGEYSMKVTGEGCVYLQTSLKYNILPEKEE--------
-FPFALGVQTLPQTCDEPKAHTSFQISLSVSY-----TGSRSASNMAIVDVKMVSGF-IP
LKPTVKML--E-RSNHVSRTEVSSN--HVLIYLDKV-SNQTLSLFFTVL--QDVPVRDLK
PAIVKVYDYYETDEFAIAEYN-------------APCSKDL-------------------
------GNA---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|125987071|ref|XP_001357298.	Drosophila pseudoobscura
------------------------------------------------------------
--------MRRADAFAVTVCA---------------------------------------
------------------------------------------------TLALLQMMEPVK
CEG-------------------------------KYTIVGPGTIHSHRDYNVAVAVHQTQ
EPVTLKIGITGPSFNETQ----TVELAKSDEFK-QITFKLPPLET-----GDYNLTAEG-
--VSG--LIFVNTTKLNYDDFKPYIKIQTDKGKYKPGDTINYRVIFLDENLRPDT--AED
GVVVWFEDSKRNRIKQEKHIKTTSGVYTGKFELSEFATLGTWTLLV-HNGENQQGRSFYP
GGRHFGH------FRSDERVSFEVEKYVLPKYTIKMDATQQVSVRDGDINIVLKANYTYG
KPVNGKVLVNVHMDETS--VW---E-----NVDGKTVRNDFPG-HSLIATADMVNGKAKF
DL---NLKEFASYLPHKTS------S--SYA-QITATLEENFTGV-KLNETSGVQLYPYR
YEMSC-PDFSSCYSFKPDKEQELVFKITLVDGSLLTDTKS-----VVKAKFTEGIRHTYG
FYHYG--SEEKQPELPEIEKKTFEFESHLNESSLVPFKVTLPD--L-PDMENYTRYYSIE
LEYADEKRELYTTYPY-----REPKKIETTDPSEE-------EKEKEWFRAEVNRPKDTW
NLKIGQEYQVTLNS--------------------------------------------SR
PLKYFF------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YNIIGRGNVLNTERV----DLAEPQKV-------------
----------------YNITLKPTFLTAPHGRIYVYYVDE-SGEFRYAEDT-FSVEVELQ
NKIEIT-GPEEVKPGADVELEIKT-PPKSF------------------------------
----------------------VGLLAVDQSVLLL--GGNNDLDKDSFNWRLGGYD----
------------------------------------TSTPWQ-------GGYSYYPGERS
GVVTMTN-AYFFY-NRTAP---ISYAQAFGFGGGT-----------------VSAMRKTA
IAQDSPVYH----TTTSALGAVPTAGF-----------SAESGAAAAAPVVRKNFAETWI
F--ADIENTETEIFKWVKTIPDTITNWVVTGFSLNTEKGLGVTDHKVNIKTFQPFFVSIR
LPYSVKRGELINVPALVFNYLPKNLDVELTLD-NQDDEFEFVDASNE---------VIGD
QK-----RTQVIRVGANEAAGASFLIRPKVIGNILLKFSAIS---------------PLA
G--DAVHKSLKVIPEGITKYQNRAFFVNLKDVGE---YKNTFELEVP-EDIVPDSQRVEF
GLVGDLLGPVIKNLENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKLTPAIETRIKRNL
QEG----------YQNMLHYRHDDGSFSSFGPGKWREEDPE---RNGSTWLTSYVLRSFS
KIKDI--IDLDEKSLESGYEFLLSRQVE-NGSFTDAGEYFY----GSQRS---SLTLTAN
ALLAL-------LEQD---KKNQTAIDKAVA----YLSAHTEESEE------LLPKSIAV
YALQKSKAPDA-AKHVASLKAL--AQQEDDRTWWTEDTEKLRASK-GCRRW-WCWVWSHD
VEITSYALLTLLET-------------------------------------EQETPDSVL
NTIRWLVAQRNSFGGFASSQDTVVGLQALIKFAEKSGYEAA-KWEVSVSNKGKREKTEKL
SATEENDLVLQTVEFP----QGTQSLEFEAKGTGAALIQISYQYNVVEKETK--------
-PSFKIQTIVKPES-----SPAKLELSVCVEYVE---EGKAKASNMAILEVSLPSGY-TA
DEDSFKDI--K-DIERVRLVETKNGDSVIVVYFENLLRGELKCIPFDAF--RTHAVANQK
PAPVVLYDYYDTNKKATEYYQ---IE----SKLCDIC-EDS-------------------
------ECKS---KC---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
>gi|58389525|ref|XP_317088.2|	Anopheles gambiae
------------------------------MRRSTMFASKKDPA----------------
------IRILSTSSSSLLAVC---------------------------------------
------------------------------------------------LVLSVALVPAVQ
CEG-------------------------------HYSIVGAKLLRPNSEYHVAVTNQDVS
EPIRFSLAITDASSVIAK----QEITLNTGETR-LVPFAIGDISE-----SSYKLVAEG-
--LSG--LTFKNETDLEYQQKSFSVFVQTDKSIYKPGDTVRFRVLVLDPNTKPLQ--KAD
NISVHINDAKANRIKQWKEGKLVKGVFESELTLSTAPVLGAWTINV-EV-----------
LGSKHNK-------------VFEVDEYVLPKFEVTVESPGITTFKDGKVKAIIRSKYTYG
KPVKGEATVSVSPEFQF--HYV--------QPFAKDVITRKVI-P--------IDGKGSV
EF---DLREDIH--LEGDY------S--RNI-VIEAVVEEELTGR-KQNASAKVMIYDRR
YKMEL---VKSDDNFKPGLPYTAWLKVSYQDGAPVQDQTN-----PVEVKQSSFESTT--
-------SVQNYT---------------LDQNGMAKLEINTEV----NSS-----YINVV
GVYLGQ-------EFY-----LHGISK-------------AESDVDSYIRAQVLTEM---
-PLVGKDVLVEVTS--------------------------------------------TS
PMKYFT------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YQLLGRGDVLLSNTI----AVPESKTQ-------------
-----------------SFKFPATFAMVPRAKLVVYYIAP-NGDMVSDSKV-ITFDSELQ
NFMKVSLSKEQSKPGQDVEISIST-NPDSY------------------------------
----------------------VGLLGVDQSVLLL--KSGNDITKQQVFSELEKYEE---
RSYGFYRRKKRF------------------------AWNPHA--------EHRDF--STV
GAFVMSN-----------------------------------------------------
---------------ANDPPR---------------------------------------
----TEQSSFSGEKTLQKKVPDTITSWIITGFSVNPIYGLGLTQQPRKLNVFLPFFVSTN
LPYSVKRGEVVAIPIVVFNYMEDDQTAEVVLH-NDEQEFEFADVENE---------VVES
NK-VELFRQKRLDIASNTGKSVSFMVKPKKLGHITIKVTAKT---------------KIA
G--DAVERQLLVEPEGLPQFINKAAFIDLRAAPE---LTKTFEVEIP-KNAVPDSTRIEV
AVIGDVMGSTIQNLDSLIRMPYGCGEQNMLNFVPNIVVLDYLKATNKLTANIEAKAKKFM
EAG----------YQRELGYKHRDGSFSAFG-------END---KSGSTWLTAFVARSFK
QAANH--ITIDEGVIDKSLEWLSDHQAP-NGSFPEVGVVSHKDMQGGSGS---GVALTAY
TLIAF-------LENINLVDKYKNTINKAID----YVYRNTESLDD------TYALALAA
YALQLADHSSK-GLILSKLDTK--ATTDSDSKWWHKPIPETE----QKNPW-YSRPNSVN
VEMSAYGMLAFL---------------------------------------EAGLDTDAL
PIMKWLIGQRNDKGGFQSTQDTVVGLQALAKLAAKITSPNN-DVTLTAKINENQEK--RM
TVNAENGMILQKFELP----SAARNIEIQATGSGFAVVQLSYKYNMNVTGEW--------
-PRFVLDPQVNANT-----NPDYLHLSVCASFVP---SAGQNVSNMAVMEVGFPSGF-TA
DSDTLPSL--E-NMPFIKKVETKDGDTTVVLYFDSL-DQRELCPTISAF--RTHKVAKQK
PAPVVIYDYYDNSRIARQFYD---GPK---ASLCDIC-ENE-------------------
------DCGE---ACSIRSQKQRSSDSPSRQPTVEGTMQSG-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------SQTVSVSF-FTFLLATL
L-------------------------VRMFH---
>gi|119115834|emb|CAJ18866.1|	Drosophila simulans
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------LYSVVGPGTLRSNSKYNVVVSVHKAD
APSQIKVSLNGPSYNET-----KQIELPPMSTQ-NVEFEVPKLAT-----GNYNLTAEG-
--LSG--VVFKNSTKLNYADEKPSVFVQTDKATYKPADLVQFRILFLDENTRPAK--IEK
PISVIITDGAQNRIKQLNDVKLTKGVFSGELQLSEQPVLGTWKISV-SVD----------
GDNRETK-------------SFEVDKYVLPKFEVIVDTPKAAVIEDKVIKATIRAKYTYG
KPVKGKATVSMERSYGY--FG---------NLGENDYKQEKTI-D--------VDGKGHV
EF------DIISWTQRGQY------L--PPV-KLFAVVTEELTGN-KQNATATVVLHQQR
YMIEA---YERPDHFEANKSFIYQVVVKNVDGSPVTSSAK-----NVKIGFTNTFS----
-------YFIEMPPVSRINYEAP-----VNENGIATFNVTLPD----SES----RYYRIF
ASFDRSINQ----LGS-----ISKFEPT------------MISREP--LKIQVNTKK---
-PRLGERVSFDVVS--------------------------------------------IE
DLPYFV------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------YTIVARGNVILSDYV----DVPDGKKT-------------
----------------FTVKFTPTFSMVPKATIYVHYVV--NNDLQFEEKT-IDFEKEFS
NSIDIS-APTNAKPSEEVKLRIKT-DADSF------------------------------
----------------------VGLLGVDQSVLLL--KSGNDLSQDDIFNSLNKYQ----
------------------------------------TSTPWM-------NGYGRYPGQTS
GLVTLTN-ANYPY------------------------------------------NTDFA
IAFSLAGEA----PGMGSPPTSPP-------------------------QIRKEFPENWI
F--YNAEXXXXXXLTLTKKIPDTITSWVVTGFSLNPTSGIALTKSPSKIRVFQPFFVSTN
LPYSVKRGEVIAIPVVIFNYLDKTLDADVVMD-NSDQEYEFTEATNE---------VLEK
AI-DEVRRVKRVTIPANSGKSVSFMIRPKSVGFTTLKITATS---------------ALA
G--DTIHQKLKVEPEGVTQFENRAVFINLKDQPE---MSQSLDAEIP-SEVVPQSEFIEF
SXXXXLLGPTLQNLDNLVRMPYGCGEQNMVNFVPNILVLKYLEVTGRKLPSVESKARKFL
EIG----------YQRELTYKHDDGSYSAFG-------KSD---ASGSTWLTAYVMRSFH
QAGTY--TDIDPKVITAGLDFLVSKQKE-SGEFPEVGKLFDNANQN-------PLALTSF
VLLAF-------FENHELIPKYQGAIEKAVR----YVAEEADKTDD------QYSLAIAA
VALQLAKHPQA-EKVLAKLESM--ARNENDRMWWSKTTESTG----EDGRVFHWKPRSND
VEITSYVLLALL---------------------------------------EKDPAEKAL
PIIKWLISQRNSNGGFSSTQDTVIGLQALTKFAYKTGSGSG-TMDIEFSAAGESNN--TI
KVNPENSLVLQTHVLP----KSTRKVDFTAKGTGSAMVQLSYRYNLAQKEKK--------
-PSFKVTPTVKDT------PNQLLVVDICAEYVPLEDADKEKDSNMAVMEIALPSGF-VG
DDESLSKI--Q-AVDRVKRVETKNSDSTVVVYFDSLTPGDVHCLPLEAS--KAHAVAKQK
PASVSLYDYYDTERKATEYYQ---VK----SSLCEIC-EGA-------------------
------DCGE---GCKKD------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------
