>gi|50289171|ref|XP_447015.1|	Candida glabrata
------------------------------------------------------------
-------MLVKIWPSQ-RSIVRIAAAGLQN--SR--------------------SVHSGQ
TISERLVEIGEKWKSKTLEGVPRNARVP-FIPIKENDKRDMYILSMFPYPSGMLHMGHLR
VYVISDTLNRFYQQRGYNVIHPMGWDAFGLPAENAAIERGIDPSEWTKQNIKKMKEQMND
MLANFNWEREVTTCDPEYYKFTQWLFLQLYKNGLAYRKDAEINWDPVDKTVLANEQVDAN
GRSWRSGAIVEKKKLTQWFLGITKFVDQLRDDLKY--LEE-WPNKVKTMQNNWIGSSTGM
EVNFKLN-KKIGKFE-NVTVFTTRAETLFSV-EYVVLATDHPI--TQHYAKQKSDLREFL
HKLPELP-EDTKTGYRISDLTV---ENPITHE------VIPVFVAPYVISGYGDLPAAVM
GCPAHDLRDYEFRKINLNTNEEPFGCIIPDLSRLGQDSIPY-----------TSKSGTMN
ERC---------GKYVGWDVNATRDAISTELENKNLGKRTTRYRIKDWLISRQRYWGSPI
PIIHCNNCGIVPVPEEDLPVTLPYVQG--LH-QKGNPLSNISDFVNTECPRCHNS-AKRE
TDTMDTFIDSSWYFFRYIDAHNKVLPFSPEKANKSMPVDIYIGGVEHAILHLLYSRFISK
FLSSIGMW------DRGISHGEPFKKLVTQGMVQGKTLIDPE---TGKFLTPNDIDYL-S
SSS---TPKIKGKNIAPILK-YEKMSKSKYNGADPNECISKHGPDATRAHILFQSPISDA
LRWD--EEKIVGIERWLDKILQLCMSFASNPDK----------------IVGMTGIPPDQ
YN--TDEITLYNNVSKMVNSITKSFSENLSLNTVISDYMKLTTLLENAKKNT-KIRDTVT
INYVRDLIKCIYPVVPSIAEEASCILQTHLN---------------VNVNIYEWPTA---
----REVIKSSLMNLKIFINGKMRFMYATDQSISKLDDMS--------------LLKLLS
KTEDGARLIPAKK-----LKQ-----IIRKKDLISLIFEKQ-------------------
-----------------
>gi|21355409|ref|NP_647932.1|	Drosophila melanogaster
------------------------------------------------------------
-MQALRRTRPWGAVYW-NSWRRLLTQSCTR-------------------------NDNPE
LTSDVKHRIEAHWREQLSGGQF----------NPKDSQDKYYVLSMFPYPSGNLHMGHVR
VYTIADSVARFQRMCGKNVFQPMGWDSFGLPAENAANQRGVEPASWTEQNIAQMKEQLKR
LGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPVDKTVLADEQVDAN
GCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRD-W-RDIINLQRHWIGECDGY
AFNLLTSASG------LLRVWTTHPEHLKDPHAFLVLRSNHHLSKLKGADSLSA------
-------------------------ANPFAGT------TMPVVFSDE--VTFPPKSDVYL
AAPSFRGEDKDLWD--------SYGLAFTSNGKDEESLSPAN------------------
------------WEML-------RKEVLQAATRLNVGGYRVSSKLKDWLISRQRYWGTPI
PIVHCQKCGAVPVPEEQLPVSLP-------------PKDSPKEAFLCDCPKCGEKDARRE
TDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKKFMPVDLYIGGKEHAVLHLYYARFINH
FLHSCGLS----------PTSEPFSRLLVQGMVMGRSFRVKG---SGRYVPETEVEI---
VNAKKNQAVLKETKEPVVMT-WEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPTSH
RNWS--SATFPGILNWQKRLWLTLQDFQQAREDQ---------------TASDVVPTSEE
FL--AEDAKLFDARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHV-LRHGKQF
ERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWS---EDVLAQRWPDI---
--DPAY-----NLDLSIKVNGFENCVIKVQRTHLDKVTHSD-------------ALDIAF
NTESVTSYLIDKK-----IRTTNFVLYPGIEAILNIYVDKAKMKQKPPTTDDAEAQPQA-
-----------------
>gi|73985819|ref|XP_533856.2|	Canis familiaris
---------------------------------------------------MASACRRLG
FYISFLKNQLDGGLAI-ISVGRRVIPGCAR--GI----YSAT------------GEWTKE
YTLQTRKDVEKWWHQRIKEQAS-------KISEADKSKPKFYVLSMFPYPSGKLHMGHVR
VYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIEHMRKQLDR
LGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEH
GCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD--LPE-W-YGIKGMQAHWIGDCVGC
HLDFTLKVDGQVTGE-KLTAYTATPEAIYGT-SHVAISPSHRL--LHGHSSLKETLRKAL
IPGKD----------CLTPVMA---VNMLTQQ------EAPVVILAK--ADFEGSLDSKI
GIPSTSPEDTTLAQ----TLGLPYSEVIETLPDGTERMSSS-------------------
------------AEFTGMNRQDAFLALTQKARKKRVGGDVTSNKLKDWLISRQRYWGTPI
PMVHCPACGPVPVPLQDLPVTLPHITS--FTGKGGSPLAAASEWVNCSCPRCKGA-ARRE
TDTMDTFVDSAWYYFRYTDPQNTHSPFNTALADYWMPVDLYIGGKEHAVMHLFYARFFSH
FCHDQKMV----------RHREPFHKLLAQGLIKGQTFRLP----SGQYLQREEVDL---
TGS---VPVHSETKEQLEVT-WEKMSKSKHNGVDPEEVVGQFGIDTIRLYILFAAPPEKD
ILWDVKTDALPGVLRWQQRLWTLVTRFIEARASG---------------MVPRPELLRNE
ER--AESKKLWEYKNAVISEVTGHFTEDFSLNSAIAQLMGLSSNLLQASQRV-VLHSPEF
EDALCALVVMAAPMAPHITSELWAGLAQVPRKLCA---HYAWD---AGVLLQAWPTV---
--DPKFLQQPDVVEMAVLINNKACGKIPVPQGVAQDQDK---------------VHELVL
QSELGVKLLQGRS-----IKK---AFLSPRTALINFLVQD--------------------
-----------------
>gi|50732866|ref|XP_418801.1|	Gallus gallus
--------------------------------------------MDTVALRMQSVCRRFG
ACSTCLNRQLNGFVGL-RNWTPLPSHACIR--TI----YSET------------GRWEKN
YGQETRRRVENWWFPRIKEQFC-------RISETDKSRPKFYVLSMFPYPSGKLHMGHVR
VYTISDTVARFQKMRGMQVLNPMGWDAFGLPAENAAIEHGLHPASWTQSNIQHMREQFDA
LGLSFTWEREITTCLPEYYKWTQYLFLKLFESGMVYQKEALVNWDPVDQTVLANEQVDDN
GCSWRSGAKVEQKYLKQWFIKTTAYAKAMFDALSD--LPE-W-YGIKEMQANWIGDCVGC
SLDFLLKVNGEVTGE-KLAAYTYTPEAVYGA-SHLYILPSHRL--LHGNSSLKEVFQREF
IPGKD----------SLTSVTA---VNLLTNQ------EIPVVISGK--TSFENYLDTKI
GIPCTSAEDAAVAK----NLNISFTEVIEKLPNGLEKVINS-------------------
------------EEFTGMTRQDALKALTQQAKNKGIGGDLMSDKLRDWLISRQRYWGTPI
PVIHCQTCGTVPVPYEDLPVVLPNVTT--FTGKGASPLETVPEWVNCACPRCKAE-ARRE
IDTMDTFVDSAWYYLRYTDPHNTDRPFNCDLADYWMPVDLYIGGKEHAVMHLFYARFFSH
FCHDLKMT----------KHKEPFHKLLVQGLIKNQTFRLRT---TGQYLKREEIDL---
TGT---EPVHLKSGEKVQVT-WEKMSKSKHNGIDPEELMKEYGIDTIRLYILFAAPPEQD
ILWDTKTDAMPGVQRWQTRLWTLVTKLIEARTSE---------------TMPNPEVLSKK
QK--AEARRIWEQKNLVISEVTEYFTKDHLFNAAISRLMSLSNVLHQASWPL-VLHSAEY
EDALATLCIMVAPMAPHIASEMWKGLAHIENKLCT---HHNWS---ADVLHQSWPKV---
--DPEYLQPPDVVEMSVLINNKACGKVFVPQQAARNFAE---------------VHELVL
QSELGAKHLQGRT-----IKK---AFLSPRTALINFLVQE--------------------
-----------------
>gi|50308367|ref|XP_454185.1|	Kluyveromyces lactis
------------------------------------------------------------
----------MGNFYHCGLVARRYFAQLSN------------------------------
---SNLVSIGNKWNEKVLNGIT-------KLSKDDRNK-NIYVLCMFPYPSGTLHIGHLR
VYTISDVVNRFYQLKGYNVLHPMGWDAFGLPAENAAIERKVNPAIWTKENIGKMKAQMGM
MASNFNWDREIATCDPEYYKFTQKLFLELFKNGYAYRKEAEINWDPVDQTVLANEQVDSN
GKSWRSGAQVEKKLLSQWFLGITRFAHELQHDLDG--LDG-WPSHVKRMQKNWIGESKGV
EVVFNLP-----SID-PIKIFTTRPETLYSV-QFVTLALDHSI--VRKLKEEDNNLQEFI
HRAEKLP-EDSKKGYMLSNIFC---QHPLDPK-----KTVPIFVAPYVLGNYGH--GAVM
GCPAHDQRDFDFWKEN--CPGKPMIYTVSSAEAKIDTSGPY-----------VSKDGVMN
ENA---------GDLVGLTTHEARKLVVEKLTSLGLGKASVQFKLRDWLISRQRYWGTPI
PIIHCDSCGPVAVPDADLPVKLPELDV--LS-KTGNPLSKSDEFVNVKCPSCGAP-AKRE
TDTMDTFMDSSWYFFRFTDPHNKELPFGYDNASKFMPIDFYIGGVEHAILHLLYSRFISK
FTASIGMW------DGSSSKGEPIKRLVTQGMVHGKTFVDSK---TGRFMKPEEIDN---
SDP--SNPRNRSTGELLSVS-YEKMSKSKYNGADPASCISAHGIDATRAHILFQAPVPDV
LNWD--ESKIVGIERWLERMLKFCISLCDNR------------------SITILSKTPTD
MN--QHEVALHNGVQTLLSSITTSLEKILSLNTVVSDYMKLFNLIEGSIKSS-NIREGLS
LLYLQKLTTVLYPVVPCVSEELASILMKS---------GYDWR-------QYEWPLI---
----EEIKKSEIIKYQVIINGKMRLIHEESEDFIQDTNK---------------VIETLK
CLPEGKKYLDDVV-----IKK-----IITKGKIISLVVKPN-------------------
-----------------
>gi|149728716|ref|XP_001500886.	Equus caballus
---------------------------------------------------MASPWQRLG
FYASLLKRQLNGGPDV-INWGKRVIPRRTR--GI----YSAT------------GKWTKE
YTLQTRKDVEKWWHQRIKEQAS-------KISETDKSKPKFYVLSMFPYPSGKLHMGHVR
VYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDR
LGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEH
GCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD--LPE-W-YGIKGMQAHWIGDCVGC
HLDFTLKVDGQVTGE-KLTAYTATPEAIYGT-SHVAISPSHRL--LHGHSSLKDAFRKAL
VPGRD----------CLTPVTA---VNMLTQQ------EVPVVILAR--ADFQGSLDSKI
GIPSTSSEDTILAQ----TLGLSYSEVIETLPDGTERLSNS-------------------
------------AEFTGMTRQDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPI
PVVHCPACGPVPVPLEDLPVTLPSVTS--FTGKGGSPLATASEWVNCSCPRCKGA-AQRE
TDTMDTFVDSAWYYFRYTDPQNAHSPFSAALADYWMPVDLYIGGKEHAVMHLFYARFFSH
FCHDQKMV----------KHREPFHKLLAQGLIKGQTFRLP----SGQYVQREEVDL---
TGS---VPVYAETKEKLEVT-WEKMSKSKHNGVDPEEVVEQYGLDTIRLYLLFAAPPEKD
ILWDVKTDALPGVLRWQQRLWSLATRFIEARASG---------------KVPRPQLLSDE
EK--AEARKLWEYKNSVISQVTAHFTDDFLLNSAISHLMGLSSALLQASQRV-VLHSPEF
EDALCALMVMAAPMAPHITSELWAGLALVPRKLCA---HYAWD---AGVLLQAWPAV---
--DPHFLQPPDVVQMAVLINNKACGKIPVPQQVAQDQDK---------------VHELVL
QSELGVRLLQGRS-----IKK---AFLSPRTALINFLVQE--------------------
-----------------
>gi|149632053|ref|XP_001513511.	Ornithorhynchus anatinus
---------------------------------------------------MPLPWWRLV
IYSPSLKGHLNGPPDL---VKRRPVPGCIR--QI----FSAT------------GKWTRD
YTLQTRKKVEKWWQQRVKEQFY-------RISDTDKSKPKFYVLSMFPYPSGKLHMGHVR
VYTISDAIARFQKMRGMQVINPMGWDAFGLPAENAAIERGLHPENWTQSNIKHMREQLNR
IGLCFNWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEN
GCSWRSGAKVEQKYLRQWFIKTTTYAKAMVEALAE--LPE-W-YGIKGMQAHWIGDCVGC
HLDFTLKVNGKTTGE-KLTAYAFTPEAIYGA-SHIAILPSHRL--LHGNSILKEIFQEAL
VPGKD----------CLTPVTA---MNMLTSQ------EIPVVIVAK--SNFEGSLDAKI
GIPSTSPEDTAVAR----DLGLSFSEVIETLPDGTEKLINS-------------------
------------GEFTGMTRQVAFDALTQKARSNGVGGDITSEKLKDWLISRQRYWGTPI
PVIHCQSCGTVPVPYEDLPVVLPSVTS--FTGKGASPLATASEWVNCSCPRCKRA-AKRE
TDTMDTFVDSAWYYFRYTDPHNTQSPFDKALADYWMPVDLYIGGKEHAVMHLFYARFFSH
FCNNQNMV----------RLREPFHKLLVQGLIKGQTFRLP----SGQYLKREEIDL---
SGS---DPVHAKTKEKLEVT-WEKMSKSKHNGIDPEEVVEQYGIDTIRLYILFAAAPEKD
ILWEMKSDALPGVLRWQQRLWSLTTKFIEARASG---------------EVPRPHQLSNK
EK--AEVKKLLKYKNSVISQVTAHFTEDFSLNSVISHLMGLSNVLWQASQRI-VLHSTEF
EDALASLCIMTAPMAPHIASELWAGLAHVQNKLCT---HYNWE---ADVLLQPWPTA---
--DLQELQQPDTVEMSILINNKACGKIPVPQQFTQDPEK---------------IHDLVL
QTELGRQFLQGRT-----IRK---AFLSPRTALINFLVQE--------------------
-----------------
>gi|62654544|ref|XP_343512.2|	Rattus norvegicus
---------------------------------------------------MASACQRLS
FCVSPLKRQLVSGLPV-ILWER-IIPGCSR--SI----YSAT------------GKWTKE
YTLQTRKDVEKWWHQQIKVQAS-------KISEEDKLKPKFYLLSMFPYPSGKLHMGHVR
VYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDR
LGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEY
GCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALAD--LPE-W-YGIKEMQAHWIGDCVGC
HLDFTLKVDGQDTGE-KLTAYTATPEAIYGI-SHVAISPSHGL--LHGCSSLKTALQKAL
VPGRD----------CLTPVMA---VNMLTLQ------EVPVVIMAK--PDLEGSLDSKI
GIPSTSSEDTRLAQ----ALGLPYSEVIETSPDGTERLSGS-------------------
------------AEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLVSRQRYWGTPI
PIVHCPACGPVPVPLQDLPVTLPSITS--LTGRGGSPLASALEWVNCSCPRCKGS-AKRE
TDTMDTFVDSAWYYFRYTDPHNTHSPFSSALADFWMPVDLYIGGKEHAVMHLFYARFFSH
FCHRQKMV----------KHREPFHKLLAQGLIKGQTFHLL----SGQCLKREDIDF---
TGP---TPVCAKTKERLEVT-WEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKD
ILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSG---------------TAPQPQLLNNK
EK--AKARSLWEYKNAVITQVTTHFTEDFALNSVVSQLMGLSGALSQASQRL-VLHSPEF
EDALCALLVMAAPLAPHITSELWAGLALVPSKLCD---RYAWD---AGVMLQAWPTV---
--DSQFLQKPDMVQMAVLINNKACGKIPVPQHVAQDQDK---------------VHEFVL
QSELGIKLLQGRS-----IRK---AFLSPRTALINFLVKE--------------------
-----------------
>gi|83771678|dbj|BAE61808.1|	Aspergillus oryzae
-------------------------------------------------------MLSLS
RLRLGPTRTFLAQARWKHGCCLPSVPALTR--------FATT------------VTPKGN
TRKLDLPAIDRKWQEKWHSKKSNLPSIA-SETKGNTEKPKSYILSMFPYPSGTLHMGHLR
VYTISDVLARFYRMRGHEVLHPMGWDAFGLPAENAAIERGIDPAEWTKDNIARMKEQLRS
ISTSFDWDRELATCAPEFYEHTQRIFLMLYKKGLAYQAEALVNYDPVDKTVLANEQVDAN
GFSWRSGAKVEKLNLKQWFFRITDFKEALLNDLDS--LAGGWPERVLSMQRNWLGKSYGA
KVKFPIAAEGIGCGSTEIDVFTTRPDTLYGV-EYLALSLNHPI--VLAAAETDSKLRKFL
DEAASLP-PDSKTGYKLSTVTASHPLHIIDRESPHVARRLPIFAAPYVLSDYGE--GAVM
GVPGHDSRDLAFFKEN--VQPESIPVVIEPHRASDAESGASAGHLPAGDMKAYTHEGFLN
SRC---------WKYQGLHSREAGQQIINDLRAVGHGDTVEQWRLRDWLISRQRYWGTPI
PIIHCGDCGPVPVPDDQLPVKLPKIEGDWLKGKRGNPLESSDEWVNTECPRCQGP-AKRD
TDTMDTFVDSSWYFLRFLDSANRRQPFSPSSAR---PVDVYIGGVEHAILHLLYARFIYK
FLAKSGLFPEIAHVGDVSRPLEPFKTLLSQGMVHGKTYSEPS---TGRFLHPSEMDL---
SSP--DKPVIKGTQITPNVS-FEKMSKSKHNGVDPTACALKYGADATRAHVLFSAPVSEV
LEWD--ETKIVGVERWFGRVWKLVQDAQQTLASSSYTFNPDELMLSN-HATALPYSPQNL
SG--NDADAVLFTHRTILSVTSCIENNPYGLNTVISDLTKLTNSLTSSTP----SSPQVL
YLCISSLLRLLAPIAPALASESWETLNEPIIGRYPKNESIDNAYDVPPIFDCPWPTALLT
SEQTDVLSARGGQTVAVQINGKLRFTVTVPRQLSPTTDESSE---------QDFIINRIL
ETDEGRTWLREKND----WEKRRRVIVVKGGKLVNIVF----------------------
-----------------
>gi|150864552|ref|XP_001383414.	Pichia stipitis
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MFPYPSGILHLGHTR
VYTISDVIARFKRLKGYNVIHPMGWDAFGLPAENAAVERGVNPADWTERNIDKMKEQIDF
MLADFDWDREVTTCSPDYYKWTQKIFLLLFENGLAYRKEAQINWDPVDQTVLANEQVDSE
GKSWRSGALVEKRNLEQWFIGITKYASELNRDLDY--LKG-WPQKVKAMQRHWIGESHGA
EIIFPTNNSSHQ----ELSVFTSRPDTLFSV-QFLAISINHPL--AKKAAESDTALAAFI
KESSSAS-PDSKDGY-LLRTKASIPINPFNDK--QEVFDVPIYIAPYVLDTYGH--GAVM
GCPAHDERDFDFWKLH--SPDSQIVQVVGLQDVEAAKTRGL-------DSPFTDKAGILY
DSSVLEGGLKDLGDYHGKTTKQAAHDIVKSLENHGCGSKSTQFRIRDWLISRQRYWGAPI
PIVHCDSCGPVAVPDEQLPVLLPKVSG--SSFGKGNPLDKLESFVETSCPSCGAQ-ARRE
TDTMDTFMDSSWYFFRYLDSQNEKMPFGHDVTTKNMPVDMYIGGVEHAILHLLYSRFISK
FLGDVGLW------NGKEVHNEPIKRLVTQGMVQGRTFTDPD---TGRFLKPEEVST---
LSR---EPTVIATGKVPKVS-YEKMSKSKYNGVDPEECIKQYGADSIRAHMLFQAPVSDE
LNWN--EEQIQGVQRWLRKVISLEETISRLALER-KTYSGVDTFKLENFELCGVHHDVLE
VS--QNEFNLLSDVQRYIQRIANSIEVELSFNTVISDLMKLTNAIIAASKPGEDVNYEIL
LDSYRKLLIILSPITPCTAEECWERLNSNLELEC------------KSIFHERYPT----
----HQKIESPFTKYNVFVNGRARHSFEALKSLAEKSEAE--------------ILSHIL
KYDDVSKFVAVER-----IQK-----VITKPGMISIVMTKI-------------------
-----------------
>gi|126341628|ref|XP_001379477.	Monodelphis domestica
---------------------------------------------------MTSTRQRFG
IYSSFLKGLLNVRAHA-GIWESKLNPRLSR--CI----YSAT------------GKWTRD
YTLQTRKEVERWWHQRLKDEFF-------KMSEADKSKPKFYVLSMFPYPSGKLHMGHVR
VYTISDVMARFQKMRGMQVINPMGWDAFGLPAENAAIEQSLHPQSWTQSNIKHMREQLDK
LGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYRKEALVNWDPVDQTVLANEQVDEN
GCSWRSGAKVEQKYMRQWFIKTTAYAKAMREALAD--LPE-W-YGIKGMQAHWIGDCDGC
YLDFTLKVNGKVTEE-KLSAYTLTPEAVYGA-SHIAILPSHQL--LHGNSRIKEVFQKAF
IPGRD----------CLTPVTA---VNMLTRQ------EIPVVIVAK--TKLEGSLDTKI
GIPATNSEDAIIAQ----NLDLPFTEVLETLTDGTEKLINS-------------------
------------AEFTGMTRQAASEALTQKARSNGVGGDLTSNKLKDWLISRQRYWGTPI
PMIHCQSCGTVPVPLEDLPVTLPNIMS--ITGKGVSPLAAASEWMNCSCPRCKGA-AKRE
TDTMDTFVDSAWYYFRYTDPHNTHSPFDKAVANHWMPVDLYIGGKEHAVMHLFYARFMSH
FCNAQKMV----------KHREPFHKLLVQGLIKGQTFRLP----SGQYLKREEIDL---
TGS---EPVHAKTKEKLEVT-WEKMSKSKYNGIDPEEVVKQYGIDTVRLYILFAAPPEKD
LLWDVKTDALPGVLRWQQRLWSVTTKFIEARASG---------------QVPTPHVLSHK
EQ--EEARKLGEYKNSIISQVTTHFTEDFLLNSVVSHLMGLSNALSQASQRV-VLHSREF
EDALAAVCVMASPLAPHLTSELWAGLAHVKNKLCS---HYDWN---ASVLHQSWPVV---
--DLQPKQQPDMVEMAILINNKACGRIPVPYQVARDREK---------------VHELVL
QSELGVQLLQGRT-----ITK---AFLSPRTALINFLVQD--------------------
-----------------
>gi|125977262|ref|XP_001352664.	Drosophila pseudoobscura
------------------------------------------------------------
--MQALRHTWTLRGLHRSCWKRFLTQSCT-------------------------GNEYLE
LSSDVKHRIETHWRDQLSGGQF----------NAKQPADKYYVLSMFPYPSGNLHMGHVR
VYTISDAVARFQRMCGKNVFQPIGWDSFGLPAENAANQRGVEPAAWTQQNIAQMKQQLQR
LGCSFDWTHELSTCSPQYYRWTQHLFLMLHKRGLAYQNEALVNWDPVDKTVLADEQVDAN
GCSWRSGAKVEKKLLKQWFIRTSAYAKQLLDGLDDPTLRD-W-RDIINLQRHWIGECNGY
AFTLLTSACN------LLRVWTANPEHLKDPNAFLVLRSKHYLAKLSGAGGLSV------
-------------------------ENPFAST------TIPVVFSDEAA--FPPDCDVYL
AAPSFRAEDRELWE--------SFGLAICASGTEETRLNPGN------------------
------------WELLR-------KEVLQAATRLNVGGYRVSSKLQDWLISRQRYWGTPI
PIVHCPKCGAVPVPEEQLPVTLPKRES----------SASGQDALLCECPKCGDPKAKRE
TDTMDTFVDSSWYYLRFLDAHNSERIFDPTLASQFMPVDLYIGGKEHAVLHLYYARFMNH
FLNNCGLS----------PTSEPFSRLLVQGMVMGRSYRVKG---SGRYVREDEVEV---
VNAKKNQALLKETKEPVVMT-WEKMSKSKQNGVEPGEMFDQYGTDTTRLIILADVAPTSH
RNWS--SATFPGILNWQKRLWLTLQEFQAAREE----------------ASTEVDVSSEQ
FL--AEDAKLFDARNFYVKGATFNYRHAHQLSVAISKMQGLTNSLRRTPKHI-QRHGKQF
ERALAAQIIMLAPMAPHFASELWSKFVSVKGRLNDASQELQWG---EDVLSQRWPDI---
--DAAY-----NLDLSIKVNGFENCVIKVQRTLLDKVTHSD-------------AMDIAF
NTESVTSYLIDKK-----IRTTNFVLYPGIEAILNIYVDKVQKKAKPASSSDTD------
-----------------
>gi|114586465|ref|XP_001147524.	Pan troglodytes
---------------------------------------------------MASVWQRLG
FYASLLKRQLNGGPDV-IKWERRVIPGCTR--SI----YSAT------------GKWTKE
YTLQTRKDVEKWWHQRIKEQAS-------KISEADKSKPKFYVLSMFPYPSGKLHMGHVR
VYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDR
LGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEH
GCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD--LPE-W-YGIKGMQAHWIGDCVGC
HLDFTLKVHGQATGE-KLTAYTATPEAIYGT-SHVAISPSHRL--LHGHSSLKEALRMAL
VPGKD----------CLTPVMA---VNMLTQQ------EVPVVILAK--ADLEGSLDSKI
GIPSTSSEDTILAQ----TLGLAYSEVIETLPDGTERLSSS-------------------
------------AEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPI
PIVHCPVCGPTPVPLEDLPVTLPNIAS--FTGKGGPPLAMASEWVNCSCPRCKGA-AKRE
TDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSH
FCHDHKMV----------KHREPFHKLLAQGLIKGQTFRLP----SGQYLQREEVDL---
TGS---VPVHAKTKEKLEVT-WEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKD
ILWDVKTDALPGVLRWQQRLWTLTTRFIEARASG---------------KSPQPQLLSNK
EK--AEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSV-ILHSPEF
EDALCALMVMAAPMAPHVTSEIWAGLALVPRKLCA---HYTWD---ASVLLQAWPAV---
--DPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDK---------------VHKFVL
QSELGVRLLQGRS-----IKK---SFLSPRTALINFLVQD--------------------
-----------------
>gi|148237378|ref|NP_001085563.	Xenopus laevis
-------------------------------------------------------MLGLG
LCSACLRGRLNGWALP-KNWKKALSLNVIR--SI----YSET------------GKWEKE
YGLETRKKVESCWKPRVKEQFT-------AISEVDKSKSKFYVLSMFPYPSGKLHMGHVR
VYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIEHGLRPDTWTERNIKHMREQLER
IGLCFNWDREITTCSEDYYKWTQYLFLKMYEAGLAYQKEAMVNWDPVDQTVLANEQVDEN
GCSWRSGAKVEQKYLKQWFLKTTVFAKAMSDALAD--LPE-W-YGVKSMQANWIGECIGC
FFDCILKVDGIETGE-KISAYSFNPEAVFGA-SHVAILPNHRL--LHGASSLKEALQEAY
TKGKD----------CVTRVSA---LNLFTKQ------EVPVVIAAK--TEFEGYLDTKI
GIPSAKPEDAELAD----KLGLQYVRVIVTSSDGTEMISNS-------------------
------------GKFTGLSRQEAFLAITQQASSEGVGGHLTSDKLRDWLISRQRYWGTPI
PVIHCPSCGAVPVPYEDLPVLLPSVAC--FTGKGLSPLASASEWIHCNCPRCAGA-AVRE
TDTMDTFVDSAWYYLRYTDPINSERPFDKTWADFWMPVDLYIGGKEHAVMHLYYARFFNH
FCSSQGMT----------KHREPFHKLLVQGLIKGQTYKLAS---TGRYLKKNEVDD---
TGS---EPVHLETGEKLLVT-WEKMSKSKHNGVDPEEIVDQYGIDTTRLYLLFAAPPEQD
ILWDVKTDAIPGVRRWQTRLWTITSKFIEARNFS---------------SVPNPHLLNKK
EV--AEARRIWESRNLAVLEVTSHFTEDYLFNASISQLMSLSNTLSQASSRV-ILHSSEF
EDALASLCIMVAPMAPHLASELWKGMSHVQFKLCT---QYKWD---EDVLAQQWPSV---
--DPDYLRQPDIVEVQVLINNKTFGTVGVPQEVSRDSKV---------------VQEMVL
QSDLGVTHLQGRT-----ITK---VFLSPRTALINFLVQD--------------------
-----------------
>gi|157115230|ref|XP_001658155.	Aedes aegypti
--------------------------------------------------------MRLI
QLNAFNTLKQKISAGYSEKWLRRMLSTVGS--NL---------------------LETRE
LTSSMKLEIERKWRNNLGDYRF----------DPTSDKPKRYVLAMFPYPSGNLHMGHVR
VYTISDAMARFYRLNGANVLHPMGWDAFGLPAENAAMQRKIPADKWTKQNIEQMREQLEM
LQFSFDWEREFATCDPEYYRWTQKLFLMLYEDGLAYQKEAQVNWDPVDETVLADEQVDDN
GCSWRSGAKVEKKVLRQWFVKTTRFAKALYDGLADPTLED-W-KDIIKLQKHWIGDCDGY
NFELKVK--GQKT---SIPIWTKHPEHLKEA-LFVAIHPSN----LLNSNKVNEGKLDIV
I------------------------ENPILGV------NLPVIVTEK--VNYPEGNDCYI
GVVSVEEDR---------QLATHYQIPL--------------------------------
------------NSQSKVESEDLRKNILAQASQLNLGGYPVSSKLRDWLISRQRFWGTPI
PIIHCQSCGPVPVPDANLPVKLP------LD-SVGIPLSQNDTWLKTSCPKCHSPDATRE
TDTMDTFVDSSWYFLRFLDPKNQSELVDPTLSRRLMPVDLYVGGKEHAVLHMYYARFMNH
YLHSKGLV----------SSPEPFKRLLVQGMVMGRSYRLKG---SGKYLPAAEVEV---
IDEKKNKAIEKATGAPVVAL-WEKMSKSKLNGVDPLEVLKEHGCDTLRMILLGDVAPTSH
RNWS--EATFPGILNWQKRIWMTMHDYRLLRSAI---------------EPAQTPPDTEE
FL--QQDRKLWDARNYFSAGATFNYKFSHQLSVGISKMQGLTNAIRRSAPEV-VAFSAQY
ERAIAAQIIMLAPMAPHFASELWEQFRALPNRLNSSSEEIQWD---LGVFEQNWPVI---
--DEEY-----PLDLTFKVNGFECCILKIPTKDLNQLTHQQ-------------SLDLAF
GQDAVLSYIGQRK-----VRHTDFVLYPGCDAILSITLEQLSKEDKEQLKNQTGEVKGKS
SKKDKKKKKKQKEVIEQ
>gi|156546787|ref|XP_001605772.	Nasonia vitripennis
MTMIFKDPILEKPPYQLLLALQTGKRAFADDTKRGNCSSREPRDSNHAYLNLQDQCSRFA
HWPPSRRISFINEFKWPNVIPKVTQKSCKYSIDQKNNNYTDNYLSLYLFMQYLYKKKNET
LATEHKHEIEKYWKDKIH-----------KTDGASESKEKYYVLSMFPYPSGSLHMGHVR
VYTISDSVARFHRMNGKNVIHPMGWDAFGLPAENAARERQVDPAKWTQLNIENMREQLLR
LGCTFDTHSEFATCDPEYYRWTQELFLKLYENGLLYQRETYVNWDPIDQTVLADEQVDEN
NRSWRSGAIIEKRLLRQWFVRTTVFAESLLEGLKDKTLKE-W-RDIIKIQEHWIGQCTGT
NFDFQLISDVPGYPK-SVTLWTDKPEYIENA-KFLAISSNSLLAKVEK-TESHNSLRKL-
------------------NAKV---VNPFTNE------ELPIYVTDKETLPYPDFRDDYL
GIPCLSEADIEFCK----STGIDYEAG---------------------------------
------------PVYSAEELAEKRSDILRIAKERNIGGYLVSSKLRDWLISRQRYWGTPI
PIVHCDKCGAQPVPRDDLPVKLPKLDR--SSENKNLTLKDANEWLKTSCPKCKGP-ATRE
TDTMDTFVDSSWYFMRYIDPKNTKEMFSKEEAFKSLPVDLYIGGKEHASLHLYYARFVNH
FLHHLGLV----------PTREPFRQLLVQGMVMGQSYST-K---EGRYLRPSEVLL---
TDD---GYVEKETHLPVVTN-WEKMSKSKYNGVDPSEMFSEYSTDTIRLLILGDVAPTSH
RNWS--QDTFPGILNWQRRLWQTISEFIAARKEL---------------SPEDLKIHHND
EKFVKEDDYMFDSRNYYVHGVTFNITGAQQLSVAISKMQGLTNSIRKSSKLC-VARSREY
ERALAVQIIMLAPLAPHFASELWAGFCSALHRLSNDG-ELQWD---KDVLEQRWPAV---
--DLEY-----KLKVRVRVNSKDFTTLRIPRGQLDVMTEND-------------ILEVVT
KDPKFKKHVQGRK-----ITKFIFRSEIGCGANVSINTKKEVVENISQEKAI--------
-----------------
>gi|23346617|ref|NP_694808.1|	Mus musculus
---------------------------------------------------MASTCQRLS
FYVSPLKRQLVSRPPV-ILWER-LIPGCSR--SI----YSAT------------GKWTKE
YTLQTRKDVEKWWHQQIKEQAS-------RVSEEDKLKPKFYLLSMFPYPSGKLHMGHVR
VYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDR
LGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEY
GCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALAD--LPE-W-YGIKGMQAHWIGDCVGC
HLDFTLKVDGEDTGE-KLTAYTATPEAIYGI-SHVAISPSHGL--LHGCSSVKKALQKAL
VPGRD----------CLTPVMA---VSMLTLQ------EVPIVIMAN--PDLEGSLDSKI
GIPSTSSEDTRLAQ----ALGLPYSEVIEASPDGTERLSGS-------------------
------------AEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLISRQRYWGTPI
PIVHCPACGPVPVPLQDLPVILPSIAS--LTGRGGSPLATALEWVNCSCPRCKGS-AKRE
TDTMDTFVDSAWYYFRYTDPHNTQSPFGSALADFWMPVDLYIGGKEHAVMHLFYARFLSH
FCHDQKMV----------KHREPFHKLLAQGLIKGQTFRLP----SGQCLKKEDIDF---
TGP---APVCAKTKEKLEVT-WEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKD
ILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSG---------------TVPQPQLLNSK
EK--TKAQNLWEYKNAVIAQVTTHFTEDFALNSVVSQLMGLSSALSQASQRV-VLHSPEF
EDALCALLVMAAPLAPHVTSELWAGLTLVPSKLCD---HYAWD---SGVMLQAWPTV---
--DSQFLQKPDMVQMAVLINNKACGKIPVPQHVAQDQDK---------------VHELVL
QSELGMKLLQGRS-----IKK---AFLSPRTALINFLVQE--------------------
-----------------
>gi|146324353|ref|XP_747587.2|	Aspergillus fumigatus
------------------------------------------------------------
-MYSISRLRCRPTVFIQGRWRCAVRPVLSN--FMRLATTSAT----------------SI
SRKLDLLAIDRKWQEKWHAEGPRSLPDD-ANKENRGDRPKSYILSMFPYPSGTLHMGHLR
VYTISDVLARFYRMRGHEVLHPMGWDAFGLPAENAAIERGIDPAEWTKQNIAKMKEQLRS
ISTSFDWDRELATCSPEFYEHTQRIFLMLYRKGLAYQAEALVNYDPVDKTVLANEQVDSN
GFSWRSGAKVEKLKLKQWFFRITDFKEMLLKDLDS--LTGAWPERVLTMQRNWLGKSYGA
KIKFPVAVDASGDANLHVNVFTTRPDTLYGV-EYLALSLNHPI--VLEAAEKDAALRKFL
DEAASLP-PDSKVGYKLANVTASNPLHIIDKESPHIARRLPIFVAPYVLSDYGE--GAVI
GVPGHDSRDLAFFKEN--TNSDSIPVVIEPEHLSNPNNDSTGTVTRPNDMKAFTQEGILT
SRC---------WKYQGLHSREAKKQIVTDLKGVGHGDFVEQWRLRDWLISRQRYWGAPI
PIIHCESCGPVPVPEDQLPVRLPKIEGDWLKGKKGNPLESSQDWVNTKCPSCSGP-AKRD
TDTMDTFVDSSWYYLRFPDAHNKEQPFSPSTAR---QVDIYIGGVEHAILHLLYARFIYK
FLSQTELFPEIARSGDGLGPSEPFKTVLTQGMVHGKTYTEPS---TGRFLLPSEVDL---
SNP--NKPLIKGTQVAPNIS-FEKMSKSKHNGVDPTSCALQYGADATRAHVLFSAPVSEV
LEWD--DTKIVGIERWFGRLWKLVLDAKQSLASASFTVSQNDLQKSPYATSKLPSLLQGL
GD--SDAEGLLHTHQTIVSVTNCIENNPYGLNTVISDLTKLTNTLTSSNP----TSPQVL
YLCVSSLVRLLAPVAPALASECWEVLNDTLIDQNANTGARVPD-----IFDCAWPSPLLT
SEQADVLSARGGQIVAVQINGKLRFTVTIPRRLSPTTSADS-SDSGAVTDEQDWIISRIL
ETDEGRVWLREKND----WEKRRRVVVVKGGKLVNIVF----------------------
-----------------
>gi|109041119|ref|XP_001114552.	Macaca mulatta
---------------------------------------------------MASAWQRLG
FYASLLKIQLNGGPDV-IKWERRVIPRCTR--SI----YSAT------------GKWTKE
YTLQTRKDVEKWWHQRIKEQAS-------KISEADKSKPKYYVLSMFPYPSGKLHMGHVR
VYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSKCSYSRKLLDR
TNFCFSRDREITTCLPDYYKWTQYLFVKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEH
GCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD--LPE-W-YGIKGMQAHWIGDCVGC
HLDFTLKVHGQATGE-KLTAYTATPEAIYGT-SHVAISPSHRL--LHGHSSLKEALRMAL
VPGKD----------CLTPVMA---VNMLTQQ------EVPVVILAK--ADLEGSLDSKI
GIPSTSSEDTILAQ----TLGLAYSEVIETLPDGTERLSSS-------------------
------------AEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPI
PIVHCPACGPTPVPLEDLPVTLPNIAS--FTGKGGSPLAMASEWVNCSCPRCKGA-AKRE
TDTMDTFVDSAWYYFRYTDPHNSHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSH
FCHDQKMV----------KHREPFHKLLAQGLIKGQTFRLP----SGQYLQGEEVDL---
TGS---VPVHAKTKEKLEVT-WEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPDKD
ILWDVKTDALPGVLRWQQRLWALTTRFIEARASG---------------KAPQPQLLSDK
EK--AEARKLWEYKNSIISQVTTHFTEDFSLNSAISQLMGLSSALSQASQRV-ILHSPEF
EDALCALMVMAAPMAPHITSEIWAGLALVPRKLCA---HYSWD---ASVLLQAWPAV---
--DPEFLQPPEIIQMAVLINNKACGKIPVPQQVAQDQDK---------------VHEFVL
QSELGVKLLQGRS-----IKK---SFLSPRTALINFLVQD--------------------
-----------------
>gi|6323414|ref|NP_013486.1|	Saccharomyces cerevisiae
------------------------------------------------------------
---------MLSRPSS-RFLSTKRGPGPAV------------------------------
---KKLIAIGEKWKQKTTRGLP---------KQDTLNSGSKYILCQFPYPSGALHIGHLR
VYVISDSLNRFYKQKGYNVIHPMGWDAFGLPAENAAIERSINPAIWTRDNIAKMKQQMQS
MLANFDWDREITTCDPEYYKFTQWIFLKLFENGLAYRKEAEINWDPVDMTVLANEQVDAQ
GRSWRSGAIVEKKQLKQWFLGITKFAPKLKKHLNQ--LKD-WPSNVKQMQKNWIGESVGA
ELVFKV---ADPKFE-NLIVFTTRPETLFAV-QYVALALDHPI--VQKYCEEMPDLKEFI
QKSDQLP-NDTKEGFQLPNIKA---VNPLTKE------EVPIFAAPYVVSSYGSAPSAVM
GCPGHDNRDFEFWQTN--CPGEHIKTCIAPFFDDASKVTEQERQRIIDTVPFTSTDGVLT
KEC---------GEHSGVLTVVARKSIMGMLNSEGLSKSVVRYKIRDWLISRQRYWGTPI
PIIHCDNCGPVPVPESDLPVKLPELEG--LD-TKGNPLSTIDEFVNVACPSCGSP-AKRE
TDTMDTFIDSSWYYFRFLDPKNTSKPFDREIASKNMPVDIYIGGVEHAILHLLYSRFIAK
FLGSINAW------SDPAGIFEPFKKLVTQGMVQGKTYVDPD---SGKFLKPDELTFV-N
DSPDGNTVIIKSNGKVPVVS-YEKMSKSKYNGADPNECILRHGPDATRAHILFQSPIADA
LNWD--ESKIVGIERWLQKVLHLTKNILSLEKDL---------------AISKDYKTPTD
LN--DAEVKFHNDFQRFLKSITESFEVNLSLNTVISDYMKLTNILESALKKG-EVRNEMI
VQNLQKLVTVIYPAVPSISEEAAEMINS----------QMEWN-------QYRWPEV---
----ERTTESKFKKFQIVVNGRVKFMYTADKNFLKLGRDA--------------VIETLM
NLPEGRMYLMNKK-----IKK-----FVMKFNVISFLFHK--------------------
-----------------
>gi|135143|sp|P13503|SYLM_SACDO	Saccharomyces douglasii
------------------------------------------------------------
---------MLPRPSS-RFLSTQRGPGRAV------------------------------
---KKLIAIGEKWKQKTTRGPP---------KQGTLNNRSKYILCQFPYPSGVLHIGHLR
VYVISDSLNRFYKQRGYNVIHPMGWDAFGLPAENAAIERGINPAIWTRDNIAKMKQQMES
MLANFDWDREVTTCDPEYYKFTQWIFLKLFENGLAYRKEAEINWDPVDKTVLANEQVDAQ
GRSWRSGAIVEKKQLKQWFLGITKFAPKLRKHLNQ--LKD-WPSNVKQMQKNWIGESIGA
ELVFKV---ADSKFE-NLIVFTTRPETLFAV-QYVALALDHPI--VQKYSEVIPDLKEFL
QKSDQLP-SDTKEGFRLPDIKA---VNPLTKE------ELPIFAAPYVISSYGTAPSAVM
GCPGHDSRDFEFWQQN--CPGEHIKTCIAPFFDDASKTSEKERQKIIDTVPFTSADGILT
KES---------GEYSGVFTAVARKSIMGKLHSKGLSKNIIRYRIRDWLISRQRYWGTPI
PIIHCDNCGPVPVPESDLPVKLPELKG--LD-TKGNPLSTIDEFVNVACPSCGSP-AKRE
TDTMDTFIDSSWYYFRFLDPKNTSKPFDREIASEHMPVDIYIGGVEHAILHLLYSRFIAK
FLGSINAW------DDPTGIFEPFRKLVTQGMVQGKTYVDPD---SGKFLTPDELTFV-K
DPSDGNTTIIKSNGKIPMVS-YEKMSKSKHNGADPNECILRHGADATRAHILFQSPIADA
LNWD--ESKIVGIERWLQKVLCLTKNILGLEKNL---------------AISKDYKTPTD
LN--DAEVKFHNDFQRFLKSITESFEVHLSLNTVISDYMKLTNLLESALKKS-EVRKEMM
VQNLQKLVTIIYPAVPSISEEAAELISS----------QMEWN-------QYRWPEV---
----ERTTESKFKKFQIVVNGRVKFMYTADKDFLKSGRDA--------------VIETLL
KLPEGRMYLMNKK-----IKK-----FVMKYNVISFLFHK--------------------
-----------------
>gi|91078378|ref|XP_974191.1|	Tribolium castaneum
------------------------------------------------------------
-MRFLTKSLQKLAPKR-LGFGYRHISGLNL--------------------------WHEE
ISSDIKHKIEDYWRDKLKVDDF---------DENETVRDKYYVLSMFPYPSGSLHMGHVR
VYTISDVIARFQRMNGKNVIHPIGWDAFGLPAENAAIERQIAPQDWTQSNISHMKSQLQR
LGCSFEWGRELATCDPSYYKWTQDLFLKLYDSGLVYQKKALVNWDPVDQTVLADEQVDEN
GCSWRSGAKVEKKLLRQWFVRTTRFAKDLLEGLDDPLLQD-W-RDVIKLQKHWIGECDGV
NFDFKVQ--GGDD---FLTLWTSKPEAITSV-KFVAIDSKHYLGGTPGFVLQEGTKKLNL
QL-----------------------VHPLTGH------LIPVFVTNQ--IEFLPFTDTFL
GIPGVCPQATQFAD----KFNITYEKHKDLDENEKLRLQNQ-------------------
--------------------------ICRQASELGVGGYWSSAKLRDWLISRQRFWGTPI
PVAHCDNCGAQPI--RQLPVELPKVS---MSQKGGAYLKQVADWVDCTCPKCQQK-ARRE
TDTMDTFVDSSWYYLRYLDSSNCQKMFDENKAKKMMPVDLYIGGKEHAVLHLYYARFISH
FLYSQGLL----------PEREPFKRLLVQGMVMGRSYRVKG---TGRYVPESQVKV---
IDKKKNRAVIEATGEAVVMG-WEKMSKSKHNGVDPGDMFCEYGSDTTRLLILGDVAPTSH
RNWN--SNTFPGILNWQKRLWMTIQDFLKHR------------------KTPPPSIPDDQ
FK--AHDDYMFDSRNYYIKGTTFNYCRSQQHSVAISKQQGLTNSLRRVPASI-FAKSLQF
ERALAAQIILLAPMAPHFASELWSGFVSAPNRLNHSG-EIDWE---KTVLEQKWPSL---
--DDSY-----CLDLVCKVNGVEVCNVKIPKCDIEQLGEEE-------------AIKIAL
SQKEVKEILEEKE-----VERTTYLFEPDYEGVVSVFTRWERKEKTVTL-----------
-----------------
>gi|45190649|ref|NP_984903.1|	Ashbya gossypii
------------------------------------------------------------
---------MRGFP---GAWCKRSLNTASD------------------------------
--AVDLVKVGQKWKSKVLSGVP--------QPAAEGTRPHMYVLSMFPYPSGMLHIGHLR
VYTISDALNRFYRMKGYEVVHPMGWDAFGLPAENAALERGIAPADWTRQNIARMKQQKGD
MLAHFEWGREVTTCDPEYYRFTQELFLELWHHGMAYKKEAEINWDPVDKTVLANEQVDAQ
GRSWRSGALVEKRKLNQWFLRITRFAHELSHDLDG--LDG-WPAKVKAMQKHWIGEVEGT
EVRL-----CTGDGE-AIVAFTPRIEAVFGL-QYVAISTEHAL--TKKMAERLPELCEFL
QRPLVLS-ESDLSGFQLPGTYV---QHPFAKDHGH---RIPVFVSPYVPADGAG---AVL
GTPAHDEFDHKFWRAN--KPAEPVISSFEASGECDDECHIQ-------------TKGILN
AKA---------GNLKGISSQDAKQVLADKLVATGDGRQTTQYRLRDWLISRQRYWGAPI
PIIYCDSCGTVPVPKQDLPVMLPNIAG--LS-KKGNTLEHIPEFVNTSCPSCGGP-AKRE
TDTMDTFMDSSWYFFRYLDSHNQKEPFGYDKATRSMPVDMYIGGVEHSILHLLYARFISK
FLASIGKW------DGSACNGEPFKRLVTQGMVHGKTFIDPE---NGSFLKPEELDM---
SNP--ADPIICRTGQKPRVS-YEKMSKSKYNGADPAQCISKHGPDAIRAHILFQAPISDV
VNWD--ETKIVGIERWLARIIKLAHTLAADSQLK---------------HGPVAKLTN--
----MHEIALFNEVQKLLGSITDSFSRTLSLNTVISDYMKLTNLLDQALKNK-DINPAWL
LTHFKKLVSVIHPTVPAVSEEAADIIKGHLQ-------LLTWD-------HYVWPTV---
----DAQQKDNSVGYRVFVDGKMRFIYPAPSAFINDKNG---------------VLKALL
AHPDGGKYLAGRQ-----VKN-----LILKKNIISLVLQK--------------------
-----------------
>gi|66551970|ref|XP_624911.1|	Apis mellifera
------------------------------------------------------------
-MKITKSILCYKDYKFFKNIIRYTSTGINK--------FSNV-----------------K
LTDVIKKEIEIYWKDKINLNKN--------YDDTNNEKKKFYILSMFPYSSGMLHMGHVR
VYTISDTIARFYRMKGYNVLHPIGWDAFGLPAENAAIEKQINPIEWTYDNIKNMRNQLKL
LNYSFDWDREITTCDPEYYKFTQELFLKLFEKDLVYRKESFVNWDPIDETVLAEEQVDAN
NCSWRSGAKIEKRLLNQWFIRTTSFAKSLFEGLSDPKLID-W-RDIKTIQENWIGKCDGI
SFELQLIGNILNYPK-TINVWTNYPEFIEYA-KFVAISPHSLL--------NRPEYCTDV
TEGIK-----------IMNVKV---LNPFNGN------ELPIFVTDK--VTFPNSRDTYI
GIPFASMDDFEFSK----IVG---------------------------------------
------------IEFQQHSIECKKSDILSKAQKWKIGGYPVSSRLQDWLISRQRYWGTPI
PIIHCSNCGIQPVPYNELPVLLPSIT---FSNKK-IILHEAKDWLNTSCPKCGIQ-AIRE
SDTMDTFVDSSWYYLRYIDSKNMKEMFAVDKVREIFPVNLYVGGKEHAVLHLYYARFISH
FLHSEGLL----------PSQEPFQRLLVQGMVLGKTYQVKN---TEKYLKADEVEE---
NKG---EYVEKNTKEQVTVS-WEKMSKSKHNGIDPIKFIDKYGIDTTRLFILADQAPISD
KYCN--DNTMPGILNWQNRLWKVVKTFTNYRNGV---------------SLNNFKVKPTD
PKFINDDAYMFDSRNYFLKIVTFNIIKTQQLSIAISRMQGLTNSFYRVSMEC-IQKSREF
ERALAVQIIMLAPFAPHFASELWSLFSAAKYHLINED-EIKLD---KDVLDQKWPEI---
--DMNY-----KMKLLVKINNILHKTIKIPKCEIEKLSLET-------------ALNLIE
NDPLVQKHLKNCK-----ILESKLLVKEVCDPEILILTKKYAKIVTA-------------
-----------------
>gi|114586471|ref|XP_001147597.	Pan troglodytes
---------------------------------------------------MASVWQRLG
FYASLLKRQLNGGPDV-IKWERRVIPGCTR--SI----YSAT------------GKWTKE
YTLQTRKDVEKWWHQRIKEQAS-------KISEADKSKPKFYVLSMFPYPSGKLHMGHVR
VYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDR
LGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEH
GCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD--LPE-W-YGIKGMQAHWIGDCVGC
HLDFTLKVHGQATGE-KLTAYTATPEAIYGT-SHVAISPSHRL--LHGHSSLKEALRMAL
VPGKD----------CLTPVMA---VNMLTQQ------EVPVVILAK--ADLEGSLDSKI
GIPSTSSEDTILAQ----TLGLAYSEVIETLPDGTERLSSS-------------------
------------AEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPI
PIVHCPVCGPTPVPLEDLPVTLPNIAS--FTGKGGPPLAMASEWVNCSCPRCKGA-AKRE
TDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSH
FCHDHKMV----------KHREPFHKLLAQGLIKGQTFRLP----SGQYLQREEVDL---
TGS---VPVHAKTKEKLEVT-WEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKD
ILWDVKTDALPGVLRWQQRLWTLTTRFIEARASG---------------KSPQPQLLSNK
EK--AEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSV-ILHSPEF
EDALCALMVMAAPMAPHVTSEIWAGI----------------------LYNCHTEV----
-----------LEIFPLQLGHRTSHTGPAH------------------------------
------------------------------------------------------------
-----------------
>gi|156229821|gb|AAI51832.1|	Danio rerio
------------------------------------------------------------
--------MAVWRPAV-CLWGPGRSNPVIR--VSVCSLFSES------------GVWEKE
YKAETRRRVEQWWHGRIQEQWR-------TDAEDQSSRKKFYVLSMFPYPSGRLHMGHVR
VYAISDTISHFQKMRGHQVLNPMGWDAFGLPAENAAIERNLDPEDWTRSNIESMRTQLDS
LGLCFNWDREITTCLPDYYKWTQYLFIKMFEAGLAYQKEALVNWDPVDQTVLADEQVDEN
GCSWRSGAPVEQKMLKQWFIKTTNYAKPLLDALAD--LPE-W-YGVKSMQANWIGDCSGC
FFNHTLKVDGRDTGE-VLSAYSSSPETVFGA-AYVSILPSHRL--LHGSSALKSALLRAL
RPGRD----------SLTEVTA---LNLLTGR------ELPVVISAK--SQFSGHLDTVI
GIPDSSEEEAAVAQ----SLGLSWSSVLKTEADGTHALINS-------------------
------------DEFTGQSREEAFNSVTQKARQMNVGGHLTSAKLRDWLISRQRYWGTPI
PIVHCGSCGPVAVPEDELPVTLPKIPA--LTGKGASPLKTAEDWLNCQCPRCKGP-AERE
TDTMDTFVDSSWYYFRYTDPQNPLRPFERSRADHWMPVDVYIGGKEHAVMHLYYARFLSH
FCRDQSMT----------AHREPFRKLLVQGLIKGQTFTLEH---TGQYLKKEDIDF---
TGP---DPVEKSSGRRLTVT-WEKMSKSKHNGVDPQEVLQQYGISTLRLYLLYAAPPEQD
ILWDVKTDAIPGVLRWQSRLWGLVSKLRSVREGP---------------ETPNPSILNKR
ER--SEAKKIWDNKNYTLTQVTGHFTEDFLFNAAISRLMGLTNTLSQASTRV-VLHSVEF
EDALASLCIMAAPMCPHLAPELWAGLSQVRSPLGS---VLSGK---GSVLQQPWPSV---
--DPEYLQTSDTLQLSVRINNKACGEVSVPREVAHDLQK---------------LQELVL
NSPLGARLLSDRT-----IKK---AILPPRTALINFLVDE--------------------
-----------------
>gi|47220815|emb|CAG00022.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------KKKFYVLSMFPYPSGRLHMGHVR
VYTISDTIGHFQRMRGHQVLNPMGWDAFGLPAENAAIERGLDPEEWTKSNIQSMREQLDS
LGLCFDWDREVTTCHPDYYKWTQYLFIKLYEAGLAYQKEAVVNWDPADQTVLADEQVDEN
GRSWRSGAVVEQKLLKQWFIKTTNYAKPLLDSLAD--LPE-W-YGVKAMQANWIGECSGC
YFDFKLKVNGEETGD-TLSAYSSSPETVFGA-AYLAILPTHRL--LHGNSSVRFALEKAF
KPGTD----------CLTEVTA---SNLFTGL------EVPLVILHK--EAFDGYLDTVI
GVPDCSEADLAIAR----SLNLSWTTVLKEDNDGMQMLINS-------------------
------------SEFSGLTRQQGFDSITQKAREQKVGGHLTSSKLRDWLISRQRYWGTPI
PVVHCESCGTVAVPEEELPVTLPKLTS--LTGIGASPLEAAHDWVNCKCPRCKGP-ARRE
TDTMDTFVDSAWYYFRYTDPRNPHRPFDSQLADHWLPVDVYIGGKEHAVMHLYYARFLSH
FCRDLGLV----------AHREPFWKLLVQGLIKGQTFKRAD---SGQYLKREEIDF---
TGK---EPVARDGG-RVEVT-FEKMSKSKHNGLDPQDVVQQYGVDTVRLYILYAAPPEQD
ILWNVKTDALPGVLRWQSRLWQLVTKLRGARQLG---------------DVPVPTSLKKK
EL--AEAKKIWENMNYTIQE--------------------------SATVRV-VQHSLEF
EEALAALVLMTAPMAPHLASELWAGLCQVNHPLSE---LLQRG---GDVLQQQWPTV---
--DPKYLDVPDFVELSVLINNKARGTVTIPLQATKDLEL---------------VQRHVL
QSPLGQKLLAGCS-----IKR---AVLSPRTALINFLIDE--------------------
-----------------
>gi|115398550|ref|XP_001214864.	Aspergillus terreus
-------------------------------------------------------MQPLY
RLRLNPARTLRAQPRWPRPSRPLLVPVPVPVRLA--------------------TTATSL
SKKLDLLAIDRKWQEKWHTDAA--AKPS-SVNGAAPDKQKSYILSMFPYPSGTLHMGHLR
VYTISDVLARFYRMRGHDVLHPMGWDAFGLPAENAAIERGIDPAEWTRDNIARMKAQLRS
ISTSFDWDRELATCAPEFYEHTQRIFLKLYEKGLAYQAEALVNYDPVDKTVLANEQVDAN
GFSWRSGAKVEQLNLKQWFFRITAFKEALLKDLDS--LSGGWPERVLTMQRNWLGKSYGA
KIKFPVNVEGSKKTDLHVDVFTTRPDTLYGV-EYVALALNHPI--VLEAAKKDTALRQFL
DEAASLP-PDSKAGYKLADVKVSHPLHIIDKESPDVARKLPVFAAPYVLSDYGE--GAVM
GVPGHDSRDMAFFKEN--ENPEFIPMVIEPEPTTGADSNPSACLVPAEDAKAITQEGFLS
ARC---------GKYHGIQSREAGKQIISDLNRVGHADAVEQWRLRDWLISRQRYWGAPI
PIIHCGDCGPVPVPDDQLPVKLPKIEGEWLKGKRGNPLEASDEWVNTKCPSCGSA-AKRD
TDTMDTFVDSSWYYLRFLDPANKDRPFSPSLAR---PVDVYIGGVEHAILHLLYARFIYK
FLAQSEISPELPKSEESSAPAEPFKTLLSQGMVHGKTYSEPS---TGRFLHPDEVDL---
SSP--DKPLIKGTQVTPNVS-FEKMSKSKHNGVDPTQCALKYGADATRAHVLFSAPVSEV
LEWD--ETKIVGIERWFGRLWKLVLEAQQTLVSSSYLPDLD--------TAAMPDSLQGL
SD--SDADAVLFTHRTISSVTSCIETNPYGLNTVISDLTKLTNALASSTP----TSPQIV
YLCVSSLLRLLAPVAPALASECWEILHNTTVQNEVAG-SAGGA---RTIFDCPWPTPLLS
AEQVGALATRGGQTVAVQINGKLRFTVTVPR-MPSTTASEPSGKSGMTAEGQDWIVSRVL
ETEEGRTWLQQKND----WERRRRVIVVKGGKLVNVVF----------------------
-----------------
>gi|68475681|ref|XP_718047.1|	Candida albicans
------------------------------------------------------------
---------MIKHVEIIHRVRYSTASTIAK------------------------------
--KIQFSKLDEKWKAKWKSQSPTGSLHP-TKHLIPETNEKFYSLAMFPYPSGVLHIGHLR
VYTISDVVARYKRSKGFNVIHPMGWDAFGLPAENAAVERNINPSEWTETNIAKMKNQMET
FLADFDWQREVNTSSPEYYKWTQKIFLMLFERGLAYRKAAEINWDPVDNTVLANEQVDAE
GRSWRSGAIVEKRNLEQWFIGITKYAKELNRDLKN--LPD-WPEKVKTMQKNWIGESNGV
EINIPVNFPGLE----HVTVFTSRPDTLFSM-QFVALALNHPI--VEAAAREDQELAAFI
ESAKSIDDPTSKAGYMLKNIKASIPIDVDNNI--KKSFDIPVFTAPYVLGNYGH--GAVM
GCPGHDERDFDFWKLNG-PRGVPAIQIITPKKQNAKDDYPY-----------TLKKGTLE
DSSVLTHGLNDIGEYKGKTIEKATQMITDCLKSHSLGDYTTHFKIRDWLISRQRYWGAPI
PIVHCHDCGPVAVPDKDLPVMLPGVKG--KNFGKGNPLGNIEEFVNCKCPSCGKD-ARRE
TDTMDTFMDSSWYFFRYLDSKNENLPIGPE-ASKQMPVDLYVGGVEHAILHLLYSRFIAK
FLSDCGLW------DGEPHHKEPFKKLVTQGMVHGKTFSDPI---TGKFLIPDELDF---
TDP--ANPLIKTTGKTPVVT-FEKMSKSKHNGADPGEFIERYGADVIRAHLLFSAPVSDT
LNWQ--EEQISGTDRWLRRVIQLGDSITEIPKDQFKTEASGSSQTFQNVTLNKVHYDSIE
FN--SQELELYNTIQGYVQSIASSIEVKFSLNTIVSDLMKMTNTISEAIKTTNTYNQDLI
FDSYQKLLICMSPVTPATAEECWERFALNQGKPAP-----------KSIFYEKFPT----
----DVPIESNLTMYNIFINGKHRGTMEAPKSFAKESETE--------------IVKQIS
GAEKFNDLITGP------VKK-----VIAKPSMISIVFK---------------------
-----------------
>gi|121703584|ref|XP_001270056.	Aspergillus clavatus
------------------------------------------------------------
-MQSLSRLRISPTALAQVRWRCDAHRPFSSNTVR----FATT--------------SSAI
SRKLDLLAIDKKWQAKWQADGPRSFPNGGAQKERRGDKPKSYILSMFPYPSGTLHMGHLR
VYTISDVLARFYRMKGHEVLHPMGWDAFGLPAENAAIERGIDPAEWTKQNIAKMKEQLRS
ISTSFDWDRELATCSPEFYEHTQRIFLMLHKKGLAYQAEAVVNYDPVDKTVLANEQVDAN
GFSWRSGAKVEKLKLKQWFFRITDFKEMLLNDLDS--LAGGWPERVLAMQRNWLGKSYGA
KVKFPVTVDGGYDENLHVSVFTTRPDTLYGV-EYIALSLDHPI--VLKAAEEDAALRKFL
DEAASLP-SDSKAGYKLSSATASNPLYIIDKESPHIARKLPIFVAPYVLSDYGE--GAVM
GVPGHDSRDLAFFKEN--MNPESIPVVIESEHSAETNADNSDSLVPAGELKAFTQEGVLT
SRC---------WKYQGLHSREAKKQIVDDLNGIGHGEPVEQWRLRDWLISRQRYWGAPI
PIIHCKSCGPVPVPDEQLPVQLPKIEGDWLKGKKGNPLESSQEWVNTTCPSCNGP-AKRD
TDTMDTFVDSSWYYLRFLDSQNKEQPFSPSTIR---PVDIYIGGVEHAILHLLYARFIYK
FLAQSELFPEIARTGDLPGPSEPFRTLMSQGMVHGRTYSDPS---TGRFLLPSEVDL---
SNP--NQPLITGTQVTPNIS-FEKMSKSKHNGVDPTSCALKYGADATRAHVLFSAPVSEV
LEWD--DSKIVGIERWFGRLWKLVVDAKQSLGASSFTVSQADVEASSGHATTLPALLQGI
SD--SDADSVLHTHQTVSSVTNCIEKNPYGLNTVISDLIKLTNTLTSSTP----TSPQVL
YLCVSSLIRLLAPVAPALASECWEVLHGPIIRENSST-KPTDEAIVPPIFDCPWPSPPLT
DEQVNVLSARGGQTVAVQINGKLRFSVTIPRRLSPTTPAESGDQPGGATQEQDWIISRVL
ETDEGRVWLREKND----WEKRRRVVVVKGGKLVNIVF----------------------
-----------------
>gi|40788954|dbj|BAA04877.2|	Homo sapiens
--------------------------------------------------RMASVWQRLG
FYASLLKRQLNGGPDV-IKWERRVIPGCTR--SI----YSAT------------GKWTKE
YTLQTRKDVEKWWHQRIKEQAS-------KISEADKSKPKFYVLSMFPYPSGKLHMGHVR
VYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDR
LGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEH
GCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAD--LPE-W-YGIKGMQAHWIGDCVGC
HLDFTLKVHGQATGE-KLTAYTATPEAIYGT-SHVAISPSHRL--LHGHSSLKEALRMAL
VPGKD----------CLTPVMA---VNMLTQQ------EVPVVILAK--ADLEGSLDSKI
GIPSTSSEDTILAQ----TLGLAYSEVIETLPDGTERLSSS-------------------
------------AEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPI
PIVHCPVCGPTPVPLEDLPVTLPNIAS--FTGKGGPPLAMASEWVNCSCPRCKGA-AKRE
TDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSH
FCHDQKMV----------KHREPFHKLLAQGLIKGQTFRLP----SGQYLQREEVDL---
TGS---VPVHAKTKEKLEVT-WEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKD
ILWDVKTDALPGVLRWQQRLWTLTTRFIEARASG---------------KSPQPQLLSNK
EK--AEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSV-ILHSPEF
EDALCALMVMAAPLAPHVTSEIWAGLALVPRKLCA---HYTWD---ASVLLQAWPAV---
--DPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDK---------------VHEFVL
QSELGVRLLQGRS-----IKK---SFLSPRTALINFLVQD--------------------
-----------------
