>gi|50657364|ref|NP_001002827.1	Rattus norvegicus
--------------------------------MQRQWLLL--------------------
--LLLPLSFPVILTRELLCGGSP-------------EPCANGGTCLRLSQGQGT-CQCAP
G-----FLGETCQFPDPCWDTQLCENG---GSCQALLPTAPSSHSPTSPLTPHFSCTCPS
GFTGD------------------RCQSPLEELCPPSFCSNGGHCSVQV------------
-----SGRPQCSCEPGWTGEQCQLRDFCSANPCANGGVCLATYPQIQCRCPTGFEGHICE
--RDVNECFLEPGPCPRGTSCHNTLGSFQCLCPVGQEGPQCKLRKGACLPGTCLNGGTCQ
LVPEGDTTFHLCLCPPGFTG---LNCEMNP-----DD--------CVRNQCQNGATCQDG
LGT-YTCLCPKTWKG-------WDCSEDID----------ECEAQGPPRCRNGG---TCQ
NSAGGFHCVCVSGW-GGEG---C-------DENLDDCAA--ATCALGSTCIDRV-GSFSC
LCPPGRT----G------------LLCHLE-DMCL----RQPC-HVNAQCS--TNPLTGS
TLCICQPGY---SGP------------TCHQ-DLDECQMAQQGPSPCEHGGSCINTPGSF
N-CLCLPGY----TG-----------------------SRCEADHNECLSQPCHPGSTCL
DLLATFQ--CLCPPGLE-GR---LC--------EVEINECASNPCLNQA-----------
------------------------ACHDQLNGFLCLCLPGFTG---ARCEKDMDECSSAP
CANGGHCQDQ------------------------------------------------PG
AFHCECLP-------------GFEGPR---CET--------EADECRS-DPCPVGASCLD
---------LPGAFL---------------------------------------------
-------CL--CRPGFTGQ---LCEVPL------------CSPILCQPGQQCQDQEHRAP
---CLCPDGSPG----CVP------------------AEDD-------------------
--------C---PCHHGH-CQR------SLCVCNEGWTGP---ECE----------TELG
GCLST-PCAHGGTCHPQPSGYNCSCLAGYT------------------------------
-----------------------------------------------------------G
---LTCSEEITA---------CH--SGPCLNGGSCSIHP---------------------
---------------------EGYSCTCPPSHT-----------------------GPHC
QTAVDHCASASCLNGGTCMS--KPGTFFCHCATGFQGLHCEK-----------KIHP-SC
AD-------------------NPCRNKATCQDTPRGAR-----CLCSPGYTG--------
SSCQTLIDL--------------CA-RKP--CPHTARCLQS--GPSFHCLCHQGWTGSLC
DLPLS-CQAAAMSQGVE-I----SNLCQNGGLCIDTGSSYF--CRCPPGFEGKLCQDTVN
PCTSKP-------CLHGATCVPQPNG--YVCQCAPGYEGQNCSKVHDACQSG----PCHN
-----------------------------------------------HGTCTPRPGGFH-
-CACPPGFVGL--RCEGDVD---------ECLD-----RPCHPSGTASCH-SLANAFY-C
QCLPGHTG---QRCEVEMDL--------CQSQP---CSNGGSCEVTTGPPPG--FTCRCP
EGFEG--PTCSRKAPA---C-GNHH------C-------HNG---GLCLPSPKPGSPPLC
ACLSGFGG---PDC---LTPPAPP--GCGPPSPCMHNGSCTETPGL---GNPGFQCTCPP
DSPGPRCQRPGA------------NGCEGRGGDGA-CDAGCS------------------
-GPGGDWDG----GDCSLGVPDPWKGCPPHSQ-------CWLLFRDGRCH-----PQCDS
EECL---------------------FDGYDCEI----PPTCTPAYDQYCRDHFHNGHCEK
G-----------------------------------------------------------
----------------------------CNNAQCGWDG----------------------
-----------------------------------------GDCRPEGDDSEGGPSLALL
VVLSPPALDQQL------------LALARVLSLTLRVGLWVRKD---SEGRNMVFP--YP
G----TRAKEELSGTRDSSSW----------ERQAPHTQTPGKETESLGA----------
--------------------------------------------GFVVVMGVDLSRCGPE
HPAS--RCPRDSGLLLRFLAAMAAVGALEPLLPGPLLAAHPQAGT-GSPATRLPWPILCS
-PVVGVLLLALGALLVLQLIRRRRREHGALWLPPGFIRRPQTQQAPHRR-----------
-RPPLGEDNIGLKAL-------------KPEAEVDEDGVVMCSGPEEGE------AEKTA
SASRCQLWPLRSGCEGLPQAVMLTPPQ-ECESELPDSDTCGPDGVTPLMSAVFCGGV---
QSTTVQRLGLGNPEP--WEPLLDR----GACPQAHTVG---TGETPLHLAARFSR-PTAA
RRLLEAGANPNQPDRAGRTPLHTAVAADAREVCQLLLASRQTAVDARTDDG-----TTPL
MLAA----RLAVEDLVEELIAARADVGARDKRGKTALHWAA-AVNNARAARC--------
LLQTGADKDAQDSREQTPLFLAAREGAVEVAQLLLEIGAARGL--------RDQAGLAPA
DVARQRSHWDLLTLLEG----AGPITQEARSHARNTPGG----GAAPRCRTLS--AGARP
RGGGACLQAR---TWSVDLGARRGAVY----------ARCRSRSG--------GS-GGPS
MRGRRLSADS------------------------RGRRG--ARVSQDDWPRDWVALEACG
SACSAPIP----------------PPSL--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------TPSPERGS--------
------------------------------------------------------------
------------------------------PQVSWGLPVH--------------------
-----------------QEVPLNSGGRNQ----N--------------------------
---------------------------------------------------
>gi|109110462|ref|XP_001099317.	Macaca mulatta
--------------------------------MGAMTRLSAVVLLA--------------
--LLALLTEGGVLKKVIRHKRQS----GVNITLPEENQPVVFNHVYNTKLPVGSQCSVDL
E-----SPSGEKDLAPPSEPSESFQEHTVDGENQIVFTHRIN--------IPRRACGCAA
A-----------------------------------------------------------
------------------------------------------------------------
--PDVKELLSRLEELENLVSSLREQCAAGAGC----------------------------
-----------CLQSAI--------GRVDT-----RPF-------CSGRGNFSTEGC---
-----GCVCEPGWKG-------PNCSEP------------EC----PGNCNLRG---QCI
DG----QCICDEGF-TGED---C---------SQLACP---GDCNDQGKCVNGV-----C
ICFEGYA----G------------ADCSR--EIC-----PVPCSEEHGTCV--------D
GLCVCHEGF---AGD------------DCNK-PL--C------LNNCYNRGRCVEN----
E-CVCDEGF----TG-----------------------EDCSELI--C-PNDCFDRGRCI
NGT------CYCEEGFT-GE---DC-----------GKLTCPHACHGQG-----------
------------------------RCEEG----QCVCDEGFAG---VDCSEKR--C-PAD
CHNRGRCVDG--------------------------------------------------
--QCECDD-------------GFTGAD---CGE----------------LKCPSGCSGHG
-------RCVNGQ-----------------------------------------------
-------CV--CDEGYTGE---DCSQ-L------------RCPNDCHSRGRCVQGK----
---CVCEQGFKGY--DCSDMS----------------CPND-------------------
--------C----HQHGR-CVN------GMCVCDDGYTGE---DCR------------DR
QCPRD--CSNRGRCVDGQ----CVCEDGFTG-------PDCAE-----------------
---------LSCP------------------NDCHGRGRCVNGQ-------CVCHEGFMG
---KDCKEQR-----------C---PSDCHGQGRCMDGQ---------------------
-------------------------CICHEGFT-----------------------GLDC
GQR---SCPSDCSNLGQCVS------GRCICNEGYAGEDCSE-----------VSPPKDL
IV-------------------TEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRV
PGDQTSTIIRELEPGVEYFIRVFAILENKKSIPVSARVATY--LPAPEGLKFKSIKETSV
EVEWDPLDIAFETWEII-FRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVK
NNTRGPGLKRVTTTRLDAPSQMEVKD-VTDTTALITWFKPLAEIDGIELTYGIKDVPGDR
TTIDLTEDENQYSIGNLKPDTEYEVSLISRRG---------------DMSSNPAKETFTT
GLDAPRNLRRV---SQTDNSITLEWRNGKAAIDS-YRIKYAPISGGDHTEVDVPKSQQ-A
TTKTTLTG---LRPGTEYGIGVSAVKEDKESNP---ATINAATELDTPKDLRVSETAETS
LTLFWKTPLAKFDRYR-----LNYS------L-------PTGQWVGVQLPRNTT-----S
YVLRGLE----PGQEYNVLLTAEK--GRHKSKPARVKASTEQAPEL------ENLTVTEV
GWDGLRLNWTAADQAYEHFVIQVQEANKVEAAQNL-TVPGNLRAVDIPGLKAATPYTVSI
YGVIQGYRTPVLSAEASTGETPNLGEVMVAEVGWDALKLNWTVPEGAYEYFFIQVQEADT
VEAAQNHTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV
TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSVEIPGLRAGTPYTI
TLHGEVRGHSTRPLALEVITEELPQLGDLAVSEVGWDGLRLNWTAADQAYEHFVIQVQEV
NKVEAAQNLTVPGSLRAVDIPGLKAATPYTVSIYGVIRGYRTPVLSAEASTDTETEIGNL
NVSNITPESFSL------------SWTATDGIFETFTIEIIDSN---RLLEIVEYN--IS
G----AERTAHISGLPPSTDFIVYLSGLAPSFRTKPISATATTEALPLLENLTISDINPY
GFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT
QGHQ--TKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGIFDNFVLKIRDTKKQS
EPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQPVSAIATTAMGS---------
-PKEVIFSDITENSATVSW---------RAPTAQVESFRITYVPITGGT---PSMVTVDG
TKTQTRLVKLVPGVE-YLVNIIAMKGF-EESEPVSGSFTTALDGPSGLVTANITDSE---
-----------ALAR--WQPAIATVDSYVISYTGEKVPEITRMVSGNTVEYALTDLEPAT
EYTLRIFAEKGPQKSSTVTAKFTTDLDSPRDLTATEVQSETALLTWRPPRA-----SVTG
YLLV----YESVDGTVKEVIVGPDTTSYSLVDLSPSSHYTA-KIQALNGPLR--------
SNMIQTIFTTIGLLYPFP---------KDCSQAMLNGDTTSGLYTIYLNGDKAQALEVFC
DMTSDGGGW--IVFLRR---KNGHE------------------NFYQNWKAYA--AGFGD
RREE---------FWLGLDNLNKITAQGQYE------LRVDLRDH--------GE-TAFA
VYDKFSVGDA------------------------KTR--------------YKLKVEGYS
GTAGDSMA----------------YHNG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------RSFSTFDK--------
-------------------------------------------DTDSAITNCALSY----
------------------------------KGAFWYRNCH--------------------
-----------------RVNLMGRYGDNN----HSQGVNWFHWKGHEHSIQFAEM---KL
RPSNFRNLEGRRKRA------------------------------------
>gi|73971626|ref|XP_538811.2|	Canis familiaris
--------------------------------MGAATRLLAGILLA--------------
--LLTLTTEGGVLKKVIRHKRES----GVNVTLSEEHQPVVFNHVYNIKLPVGSQCSVDL
E-----SASGEKELAPPSEPSESFQEHTVDGENQIVFTHRIN--------IPRRACGCAA
A-----------------------------------------------------------
------------------------------------------------------------
--PDVKELLSRLEELENLVSSLREQCTTGAGC----------------------------
-----------CLQPAE--------GRLDT-----RPL-------CSGRGNFSTEGC---
-----GCVCEPGWKG-------PNCSEP------------EC----PGNCHLRG---QCL
DG----QCVCDEGF-TGED---C---------SQLACP---SDCNDQGKCVSGV-----C
VCFEGYT----G------------ADCGD--EVC-----PVPCNEEHGRCV--------E
GRCVCQDGF---AGE------------DCSE-PL--C------LNSCHNRGRCVEN----
E-CVCDEGF----TG-----------------------EDCSELI--C-PNDCFDRGRCV
NGT------CYCEQGFS-GE---DC-----------GQLSCPNACTGRG-----------
------------------------RCEQG----QCVCEPGFAG---PDCSDRS--C-PND
CHHRGRCVHG--------------------------------------------------
--RCECDA-------------GFGGPD---CGQ----------------LQCPRGCSGHG
-------HCVNGQ-----------------------------------------------
-------CV--CDEGHTGE---DCGQ-L------------RCPNDCHSRGRCVQGQ----
---CVCEPGFQGY--DCSDMS----------------CPND-------------------
--------C----HQHGR-CVN------GMCVCDDGYTGE---DCR------------DL
RCPRD--CSDRGRCVAGR----CECEHGFTG-------PDCAD-----------------
---------LACP------------------ADCHGQGRCVNGQ-------CVCHEGFTG
---ATCQERR-----------C---PGDCQGRGRCEDGR---------------------
-------------------------CTCQEGFT-----------------------GPDC
GQR---SCPNGCSGWGQCVE------GRCVCSEGHAGEDCSQ-----------VSPPKDL
IV-------------------TEVTEETVNLAWDNEMRVTEYLVTYTPTHEDGLEMQFRV
PGDQTSTTIRELEPGVEYFIRVFAILENKKSIPVSARVATY--LPAPEGLKFKSIKETSV
EVEWDPLDIAFETWEII-FRNMNKEDEGEITKSLRRPETTYRQTGLAPGQEYEISLHIVK
NNTRGPGLKRVTTTRLDAPSQIEVKD-VTDTTALITWFKPLAEIDGIELSYGIKDVPGDR
TTIDLTHDENQYSIGSLKPDTEYEVSLISRRG---------------DMSSNPAKETFTT
GLDAPRNLRRV---SQTDNSITLEWRNGKAAVDS-YRIKYAPISGGDHAEVEVPRSPQ-A
TTKTTLTG---LRPGTEYGIGVSAVKADKESDP---ATINAATDLDAPKDLRVSETTDTH
LTLLWRKPSAKFDHYR-----LNYS------L-------PSGQPVEVKLPRDTT-----S
YDLRGLE----PGKGYSILLTAEK--GRHKSKPARLNASTDHAPEL------ENLTVTEA
GWDGLRLNWTAADQAYEHFVIQVQEADTMEAPQNL-TVPGSLRAVEVPGLKAATPYRVTI
YGVIRGYRTPVLSAEASTGETPNLGEVMVSEVGWNALKLNWTAPEGAYEQFFIQVQETDS
VEAAQNLTVPGGLRSVDLPGLKAATHYSVTIRGLTRDFSTTPLSVEVLTEEVPDLGNLTV
PEVRWDGLTLDWTAPDGFYEQFVIEIQEADQAKEAHSLTVPGNLRSVEFPGLRPGTPYTI
TLHGEVGGHSTRPLVVEAITEELPQLGDLAVTEAGWDGLRLNWTAADPAYEHFVIQVQEA
NLVEAPQNLTVPGSLRAVEVPGLKAATPYRVTIYGVIRGYRTPVLSAEASTATGPEVGNL
TVSDITPESFNL------------SWTATDGAFETFTIEIVDSN---RFLETMEYN--VS
G----TERTAHISGLHPNNHFVIYLSGLAPSIRTKIISATATTEALPLLENLTISDINPY
GFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFS
QGHQ--TKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDSFVLKIRDTKKQS
EPLEITLLAPERTRDITGLREATEYEIELYGISSGRRSQPVSAIATTAMGS---------
-PKEISFSDITEDSATVSW---------MAPSAQVESFRITYVPIAGGT---SSVVNVDG
TKTQTRLMKLLPGAE-YLVSVIAMKGF-EESEPVSGSFTTALDGPSGLVTANVTDTE---
-----------ALAM--WQPAIAPVDSYVISYTGERVPEITRTVSGNTVEYALTDLEPAT
EYTLRIFAEKGPQKSSIITTKFTTDLDSPRDLTATEVQSETALLTWRPPRA-----SVTG
YLLV----YESVDGTVKEVILGPETTSYNLAELSPSTHYTA-KIQALNGPLR--------
SKLVQTSFTTIGLLYPFP---------RDCSQAMLNGDTTSGLYTIYLNGDKAQALEVYC
DMTSDGGGW--IVFLRR---KNGRE------------------DFYRNWKAYA--AGFGD
RREE---------FWLGLDNLHKITAQGQYE------LRVDLRDH--------GK-TAYA
VYDRFSVGDA------------------------KTR--------------YKLKVEGYS
GTAGDSMA----------------YHNG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------RSFSTFDK--------
-------------------------------------------DTDSAITNCALSY----
------------------------------KGAFWYKNCH--------------------
-----------------RVNLMGRYGDNN----HSQGVNWFHWKGHEYSIQFAEM---KL
RPSNFRNLEGRRKRA------------------------------------
>gi|110755204|ref|XP_001120163.	Apis mellifera
--------------------------------MHII------------------------
------------------------------------EQPVS-------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------ISNSECASNLACVNNKCKDPC-------------------PGSCGSNTECR
VVSHTAM----CVCLIGYEGDPFIQCTLKQ-----TDIQPTVSTPCIPSPCGSNAICKEQ
GGV-GSCSCLPDYIGNPYEGCRPECIMNSDCISTRACIRSKCQDPCPGACGTNA---ECQ
VVNHLPQCNCFPGY-TGQPYQFCQLITTQLEDKKDPCSP--SPCGPNSRCQVIN-DQAVC
SCLPEFT----GSPPGCRPECVVSAECSSN-LACINQKCINPCPGPCGINA-ECNVIHHS
PICACRQRY---TGDPFSRCFPMPESPSVPV-PFNPC-----IPSPCGPNAECRDINGIS
S-CSCLSNY----IGSPPNCRPECTVNSDCSLNQACMREKCKDP---C-PGSCGTFAQCT
VMNHVPI--CSCIEGYT-GDPFTNCYPKPLPQPTVSEDSCNPSPCGPNT-----------
------------------------ECNNG----ICTCLAEYRGDPYIGCRPEC--VLNTD
CPTNQACVRN-----------------------------KCINPCVNTCGQSAICNVFNH
IPMCSCPS-------------GMSGNAFILCSPIQDVV---PATPCNP-SPCGQNSQCRS
INGQAVCSCVSGYIGSPPSCRPECVVSSDCSRNEACSNLKCINPCLGTCGIQAQCQVINH
N----PICS--CPAGFSGDPFLRCNP-I--METKPEIINVCKPSPCGPNALCQVINDSPS
---CTCLPGFINSPPNCRPECVSNSECLAHHACINQKCKDP-------------------
--------C---PGSCGENADCRVVSHTPMCVCSIGYTGDPFTQCV-----PFQESIPTS
PCTPS-PCGSNAICKEQNGVGSCACLPEYIGNPYEGCRPECTV----------SSDCLSN
LACIRNKCQNPCP------------------GTCGQDAICQVINHSPT---CTCVPGFTG
DPFRYCQLMREPDKSEDETNPCI--PSPCGPNSQCRVIS---------------------
---------------------GNAVCSCLPEYTGSPHSCRPECVVSSDCPSNRACVNQKC
VN----PCPQPCGQNTNCLV--VNHSPICTCKEGNTGNPFTRCFSLPTQPTLPDLPQNPC
VP-------------------SPCGPYSECRDIGGAPS-----CSCLANYFG------SP
PNCRPECTVNSDCPSDRACIRQKCTDPCPGSCGLSSQCTVF--NHIPVCTCLEGFTGD--
--PFSNCSPAPPIETVS-EDPCNPSPCGPNAQCNNGV------CTCLAEYQGDPYLDCRP
ECVLNTDCPLTQTCLRNKCVDPCIGTCGQNAVCNVYNHVPMCS-----CPAGM---TGNA
FVFC-NPFRDPLVTNPCNPSPCGP-----------------------NSQCREVNEQAV-
-CTCILGFVGIPPTCRPECIVSTDCGPTEACINQ-KCNNPCIGSCGIRAICQVVNHNPIC
SCPVTMTGDPFVKC-IEKPLEVPPQQNPCEPSP---CGPNAQCQVINNSP-----SCSCL
PEFTGSPPNCRPECISNSECPSNLA------CINQKCRDPCPGSCGENAICNTVSHTPMC
TCSSGYTGDPFTQCILQQLIPMYIP-QPCVPSPCGANAICKERNGA-------GSCSCLP
NYIGNPY-----------------EGCRPECVLNSDCVPSKSCV----------------
-QFKCEDPCP---GTCGQNAVCQVINHVATCN-------CLPRFTGDPFRF------CRE
EEIV-------------------------TLPSVKNPCQPSPCGANSVCKE--NNGQA--
------------------------------------------------------------
----------------------------VCSCLPEFRG----------------------
-----------------------------------SPPGCRPECVASAECPFDRVCV-NQ
KCINPCPDPCGRNAICRVINRNPICSCQQGFTGDAFTICFPVPRPPPESLTPVQQDPCLP
SPCGPYSQCRNIGGNPSCSCSPSYI-GVPPNCRPE-------------------------
--------------------------------------------CTINAECLSALACIRE
KCSD--PCPGSCGVGAQC--TVLNHVPICSCLEGYTG---------DPFSSCIPKPFISE
EPVL----------------------------------DPCN------------------
-PSPCGANAF------------------------CRDGSCTCLPEFQGD-------PYSG
CRPECVMNTDCARDRACIRN--------KCIDPCIGT----------------CGQN---
-----------AQCQ--TINHIPM----CSCPAG---------MSGN----AFVSCSPVQ
EDTIQNPCSPSP-----CGPNSHCQEVNGIAVCKCIEGFMGNPPTCRPECI-----VSSD
CELS----KACINQKCRDPCPGSCGVRAE-------------CSVVNHNPIC--------
RCPQGLSGD------PF----------AACT--VIVETSPEPINPCYPSPCGPNAQCQVV
NQAPSCSCL--PEFTGS--PPNCRPECVSNS------------ECSIRQACIN--QKCKD
PCP----------GLCGANAECSVFSH----------TPICSCRT--------GF-TGDP
FVQCNPLQII------------------------EER------------------PSPCT
PTPCGANAVC--------------KESG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------NAGACSCLPDY----
------------------------------IGNP-YEGCR--------------------
-----------------PECVVNSDCTANLACVRSKCQD------------PCPG---AC
GPNAMCNAVNHLPM-------------------------------------
>gi|68533131|dbj|BAE06120.1|	Homo sapiens
SLLCASKSPILLKVRYPRALEPQQHPAKPTSTMGAMTQLLAGVFLA--------------
--FLALATEGGVLKKVIRHKRQS----GVNATLPEENQPVVFNHVYNIKLPVGSQCSVDL
E-----SASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRIN--------IPRRACGCAA
A-----------------------------------------------------------
------------------------------------------------------------
--PDVKELLSRLEELENLVSSLREQCTAGAGC----------------------------
-----------CLQPAT--------GRLDT-----RPF-------CSGRGNFSTEGC---
-----GCVCEPGWKG-------PNCSEP------------EC----PGNCHLRG---RCI
DG----QCICDDGF-TGED---C---------SQLACP---SDCNDQGKCVNGV-----C
ICFEGYA----G------------ADCSR--EIC-----PVPCSEEHGTCV--------D
GLCVCHDGF---AGD------------DCNK-PL--C------LNNCYNRGRCVEN----
E-CVCDEGF----TG-----------------------EDCSELI--C-PNDCFDRGRCI
NGT------CYCEEGFT-GE---DC-----------GKPTCPHACHTQG-----------
------------------------RCEEG----QCVCDEGFAG---VDCSEKR--C-PAD
CHNRGRCVDG--------------------------------------------------
--RCECDD-------------GFTGAD---CGE----------------LKCPNGCSGHG
-------RCVNGQ-----------------------------------------------
-------CV--CDEGYTGE---DCSQ-L------------RCPNDCHSRGRCVEGK----
---CVCEQGFKGY--DCSDMS----------------CPND-------------------
--------C----HQHGR-CVN------GMCVCDDGYTGE---DCR------------DR
QCPRD--CSNRGLCVDGQ----CVCEDGFTG-------PDCAE-----------------
---------LSCP------------------NDCHGRGRCVNGQ-------CVCHEGFMG
---KDCKEQR-----------C---PSDCHGQGRCVDGQ---------------------
-------------------------CICHEGFT-----------------------GLDC
GQH---SCPSDCNNLGQCVS------GRCICNEGYSGEDCSE-----------VSPPKDL
VV-------------------TEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRV
PGDQTSTIIRELEPGVEYFIRVFAILENKKSIPVSARVATY--LPAPEGLKFKSIKETSV
EVEWDPLDIAFETWEII-FRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVK
NNTRGPGLKRVTTTRLDAPSQIEVKD-VTDTTALITWFKPLAEIDGIELTYGIKDVPGDR
TTIDLTEDENQYSIGNLKPDTEYEVSLISRRG---------------DMSSNPAKETFTT
GLDAPRNLRRV---SQTDNSITLEWRNGKAAIDS-YRIKYAPISGGDHAEVDVPKSQQ-A
TTKTTLTG---LRPGTEYGIGVSAVKEDKESNP---ATINAATELDTPKDLQVSETAETS
LTLLWKTPLAKFDRYR-----LNYS------L-------PTGQWVGVQLPRNTT-----S
YVLRGLE----PGQEYNVLLTAEK--GRHKSKPAHVKASTEQAPEL------ENLTVTEV
GWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNL-TVPGSLRAVDIPGLKAATPYTVSI
YGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADT
VEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV
TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV
TLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEV
NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNL
NVSDITPESFNL------------SWMATDGIFETFTIEIIDSN---RLLETVEYN--IS
G----AERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPY
GFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT
QGHQ--TKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQS
EPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGS---------
-PKEVIFSDITENSATVSW---------RAPTAQVESFRITYVPITGGT---PSMVTVDG
TKTQTRLVKLIPGVE-YLVSIIAMKGF-EESEPVSGSFTTALDGPSGLVTANITDSE---
-----------ALAR--WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPAT
EYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRA-----SVTG
YLLV----YESVDGTVKEVIVGPDTTSYSLADLSPSTHYTA-KIQALNGPLR--------
SNMIQTIFTTIGLLYPFP---------KDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFC
DMTSDGGGW--IVFLRR---KNGRE------------------NFYQNWKAYA--AGFGD
RREE---------FWLGLDNLNKITAQGQYE------LRVDLRDH--------GE-TAFA
VYDKFSVGDA------------------------KTR--------------YKLKVEGYS
GTAGDSMA----------------YHNG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------RSFSTFDK--------
-------------------------------------------DTDSAITNCALSY----
------------------------------KGAFWYRNCH--------------------
-----------------RVNLMGRYGDNN----HSQGVNWFHWKGHEHSIQFAEM---KL
RPSNFRNLEGRRKRA------------------------------------
>gi|6679096|ref|NP_032742.1|	Mus musculus
------------------------------MGLGARGRRRRRRLMA--------------
--LPPPPPPMRALPLLLLLAGLG----AAAPPCLDGSPCANGGRCTHQQPSLEAACLCLP
GWVGE-RC----QLEDPCHSG-PCAGR---GVCQSSVVAG----------TARFSCRCLR
GFQGP------------------DCS--QPDPCVSRPCVHGAPCSVGP------------
-----DGR-------------------------------------FACACPPGYQGQSCQ
--SDIDEC-RSGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCR
QSSDVTYD---CACLPGFEG---QNCEVNV-----DD--------CPGHRCLNGGTCVDG
VNT-YNCQCPPEWTG-------QFCTEDVD----------ECQLQ-PNACHNGG---TCF
NLLGGHSCVCVNGW-TGES---C-------SQNIDDCAT--AVCFHGATCHDRV-ASFYC
ACPMGKT----G------------LLCHLD-DACV----SNPC-HEDAICD--TNPVSGR
AICTCPPGF---TGG------------ACDQ-DVDECS---IGANPCEHLGRCVNTQGSF
L-CQCGRGY----TG-----------------------PRCETDVNECLSGPCRNQATCL
DRIGQFT--CICMAGFT-GT---YC--------EVDIDECQSSPCVNGG-----------
------------------------VCKDRVNGFSCTCPSGFSG---SMCQLDVDECASTP
CRNGAKCVDQ---PDGYECRCAEGFEGTLCERNVD----DCSPDPCHHGRCV----DGIA
SFSCACAP-------------GYTGIR---CES--------QVDECRS-QPCRYGGKCLD
LVDKYLCRCPPGTTGV------NCEVNIDDCASNPCTFGVC---RDGINRYD--------
-------CV--CQPGFTGP---LCNVEI----------NECASSPCGEGGSCVDGENGFH
---CLCPPGSLPP--LCLP------------------ANHP-------------------
--------CAHKPCSHGV-CHDAPGG--FRCVCEPGWSGP---RCS--------QSLAPD
ACESQ-PCQAGGTCTSDGIGFRCTCAPGFQG-------HQCEV-LSPCTPSLCEHGGHCE
SDPDRLT-VCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFR---CICHRGYTG
---PFCDQDIDD---------CD--PNPCLHGGSCQDGV--GSFSCSCLDGFAGPRCARD
VDECLSSPC-GPGTCTDHV--ASFTCACPPGYG-----------------------GFHC
EIDLPDCSPSSCFNGGTCVD--GVSSFSCLCRPGYTGTHCQY-----------EADP--C
FS-------------------RPCLHGGICNPTHPGFE-----CTCREGFTG--------
SQCQNPVDW--------------CS-QAP--CQNGGRCVQT--GA--YCICPPGWSGRLC
DIQSLPCTEAAAQMGVR-L----EQLCQEGGKCIDKGRSHY--CVCPEGRTGSHCEHEVD
PCTAQP-------CQHGGTCRGYMGG--YVCECPAGYAGDSCEDNIDECASQ----PCQN
GGSCIDLVAR--YLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFR-
-CNCPPGYTGL--HCEADIN---------ECRP-----GACHAAHTRDCLQDPGGHFR-C
VCHPGFTG---PRCQIALSP--------CESQP---CQHGGQCRHSLGRGGGLTFTCHCV
PPFWG--LRCERVARS---C-RELQ------C-------PVG------IPCQQTARGPRC
ACPPGLSG---PSCRVSRASPSGATNASCASAPCLHGGSCLPVQSV-----PFFRCVCAP
GWGGPRCETPSAAPEVPEEPRCPRAACQAKRGDQN-CDRECN------------------
-TPGCGWDG----GDCSLNVDDPWRQCEALQ--------CWRLFNNSRCD-----PACSS
PACL---------------------YDNFDCYSGG-RDRTCNPVYEKYCADHFADGRCDQ
G-----------------------------------------------------------
----------------------------CNTEECGWDG----------------------
-----------------------------------------LDCASEVPALLARGVLVLT
VLLPPEELLRSS------------ADFLQRLSAILRTSLRFRLD---ARGQAMVFP--YH
R----PSPGSESRVRRELGPEVI-------------------------------------
--------------------------------------------GSVVMLEIDNRLCLQS
AEND--HCFPDAQSAADYLGALSAVERLDFPYPLRDVRGEPLEAP-EQSVPLLPLLVAGA
VFLLIIFILGV-------MVARRKREHSTLWFPEGFALH--KDIAAGHKGR---------
-REPVGQDALGMKNMAKGESLMGEVVTDLNDSECPEAKRLKVEEPGMGA------EEPED
CRQWTQHHLVAADIRVAPATALTPPQG-DADADGVDVNVRGPDGFTPLMLASFCGGALEP
MPAEEDEADDTSASI--ISDLICQ----GAQLGARTDR---TGETALHLAARYARAD-AA
KRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADG-----STAL
ILAA----RLAVEGMVEELIASHADVNAVDELGKSALHWAA-AVNNVEATLA--------
LLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHLANREI--------TDHLDRLPR
DVAQERLHQDIVRLLDQ---PSGPRSPSGPHGLGPLLCPPG--AFLPGLKAVQ--SGTKK
SRRPPGKTGLGPQGTRGRGKKLTLACPGPLADSSVTLSPVDSLDSPRPFSGPPASPGGFP
LEGPYATTAT------------------------AVS--LAQLGASRAGPLGRQPPGGCV
LSFGLLNP--VAVPLDWARLPPPAPPGP--------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------SFLLPLAPGPQLLNPGAPVSPQER--------
------------------------------------------PPPYLAAPGHGEEY----
------------------------------PAAGTRSSPT--------------------
-----------------KARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSDS---TP
SPATATNATASGALPAQPHPISVPSLPQSQTQLGPQPEVTPKRQVMA----
>gi|122890474|emb|CAM13370.1|	Danio rerio
--------------------------------MGMRGLLLASMAVA--------------
--VLVHLSSAGLVKRVIRHRRESLSPTTENLTLPSPDQPVVFNHVYNINVPSGSLCSVDM
D-----SP-GTTEIKPKSEQSDQHIEHTTDGENQIVFTHRIN--------IPKQACGCDN
HM----------------------------------------------------------
------------------------------------------------------------
--PDMKELLNRLEMLEAEVSSLREQCTSGAGC----------------------------
-----------CSAQVT--------GEVTT-----KPY-------CSGRGNYSTDTC---
-----SCVCEPGWKG-------VNCSEP------------EC----PNYCQDQG---RCE
DG----KCVCFEGF-GGED---C---------GIELCP---VDCGENGECIDGA-----C
ICAEGFI----G------------EDCSL--SNC-----PSNC-LGRGRCV--------D
DECVCDEPW---TGF------------DCSE-LI--C------PNDCFDRGRCENG----
T-CYCDEGF----TG-----------------------EDCGELT--C-PQNCNHHGRCV
NGQ------CICNIGYS-GE---DC-----------SKLTCLNDCSERG-----------
------------------------HCFNG----KCICDPGFEG---EDCSLLS--C-PDN
CNGRGHCVNG--------------------------------------------------
--ECICGP-------------GYEGDD---CSE----------------LSCLNNCHDRG
-------RCVNGK-----------------------------------------------
-------CI--CKAGFAGE---DCSI-K------------TCPHDCHGRGECVDGK----
---CVCHDGFAGE--HCGIKT----------------CPHH-------------------
--------C----HGHGQ-CVD------GKCICHKGFAGE---DCS------------IK
TCPNH--CHGQGQCIDGK----CICHDGFAG---EDCSHDCSE-----------------
---------LTCP------------------NDCHNRGRCVNGQ-------CVCNIGFTG
---EDCGTKT-----------C---PNNCLDRGFCEDGK---------------------
-------------------------CVCFEGYT-----------------------GEDC
SVL---TCPADCNDQGQCLN------GMCICDLGFTGDDCSE-----------ISPPRDL
TV-------------------TEVDPETVDVAWVNEMLVTEYLITYVPTAPGGLEMEMRV
SGEKKTATIRELEPGIEYLISVFAVLNSKMSVPVSARIATH--LPEPEGLKFKSVKETSV
EVEWDPLNIPFDGWNLI-FRN-TKEEDGEILNSLAPPETTFEQSGLGPGQEYEVKLEVVK
NNTRGPPASKNVVTMIDAPSQVDVRD-VTDTTALVTWLQPVAQVDGISVSYGPNTDSSDR
NTIELSSIETQYHLAELSPDTEYEVSLMARRG---------------EMSSFPIYETFTT
DLDSPKHLKAI---EQTDESITLEWRNSRANVLN-YRVKYGPLSGGEHGELVFPSGLQ-D
TTQAKITG---LRPGTEYGMGVTSIKEERESLP---ATTNAVTDLDPPKDLQVSETTETT
LALVWRRPVAKIDTYS-----LVFI------P-------ADGDKTELKIPGAAN-----T
YILTGLN----PGMLHTITLTAER--GRKMSAPATLSASTDEE-----------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------KPQVGNI
TISDVSWDSFSM------------SWDLDRGEVEGFLIEVSDPD---GLSDGQNHT--LS
G----QEFSLAVTDLSPSTF----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------YRVTLYGLYKGELLDPVFAEAITGLGT---------
-PKGIRFSDVTDTSATVHW---------TMPHTRVDNYRVIYVPIQGGS---PLTLRVDG
GESQAMLSNLTPGVT-YQVTVIAVKGL-EESEPGSERVTTALDKPRGLTAVNISDTE---
-----------ALLL--WQPSIATVDGYVITYSADSVAPVMERVSGNTVEFEMSSLTPAT
LYTVKVYAFRDTAKSAATSTDFTTDVDAPQNLAASNIQTETAMLTWKPPRA-----DISG
YILS----FESADGVVKEVVLSPTATFYSMSQLTASTEYTV-KLQAIAGPKR--------
SRVISTVFLTIGVLYKHP---------KDCSQALLNGDTTSGLYTIYLRGDESQPLQVYC
DMTTDGGGW--IVFVRR---QSGKV------------------EFFRNWKNYT--AGFGD
LNDE---------FWLGLSNLHKITSFGQYE------LRVDLRDK--------GE-SAYA
QYDKFSISEP------------------------RAR--------------YKVHVGGYS
GTAGDSMT----------------YHHG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------RPFSTYDN--------
-------------------------------------------DNDIAVTNCALSY----
------------------------------KGAFWYKNCH--------------------
-----------------RVNIMGRYGDNS----HSKGVNWFHWKGHEHSVEFAEM---KI
RPANFRNFEGRKKRS------------------------------------
>gi|119908478|ref|XP_873582.2|	Bos taurus
-----------------------------------------MPFLP--------------
--EAGAAGRAVALALVLLLPAVP----TGAGALLRLQPGMPHVCAEQELTLVGRRQPCVR
AFSRT-VP----VWRPGCGRQAWCVSH---ERRTVYYTGYRQVYSTE---AQTVFRCCPG
WSQQP------------------GSQGCLSPVCSSGLCFNGGHCVSGS------------
-----A---------------------------------------QPCRCPSGFQGPRCQ
--HDVDECQVHNGGCQH--RCVNTPGSYFCECKPGF-----------------------R
LHADGRT----CLAINS--------CAVGN-----GG--------CQHN-CVQLTVTQ--
----HRCQCRPEF----------QLQEDGR----------RCVRRNPCADRNGGCMHRCR
ALRGLAHCECRAGYQLAVDRKAC--------EDVDECATGLAQCAHG--CLNTH-GSFKC
VCNAGYELGADG------------RQCYRI-EMEI----VNSCEADNGGCSHGCSHSSAG
PVCTCPHGYELDEDQ------------RTCI-DVDDC-----AASPCCQQV-CTNSPGGY
E-CSCYAGYRLSADG-----------------------CGCEDVD-ECASGRGGCEHHCA
NLAGSFQ--CSCEAGYQLDEDRRGC-----------TSLELPELVLDGHLPLGRPPLHVA
VLQDELPHLFQDDYVGAEEEEAEARGEHTLQE-KYVCLDDTFG---PDCSLTC-----DD
CRNGGTCLPT--------------------------------------------------
LDSCDCPDGWTGLVCNETCPPDTFGKN---CSFS---------------CSCQNGGTCDP
VTG--ACRCPPGVGGAH-------------------------------------------
-------CEDGCPKGFYGK---HCRK--------------KC--HCANRGRCHRLYGA--
---CLCDPGLYGR--FCHLAC--------PPWAFGPGCSEE-------------------
--------C-KCEQQNTRACDKRD----GSCACKAGFRGE---WCQ----DECQPGFFGP
GCRQACTCPPGVACDPVSGECGKQCPAGYHG-------EDCGQ-----------------
----------ECPAGTFG-------------QNCSGSCSCGDAPCDRVTGQCLCPPGRTG
---DDCGADCPEGRWGL---GCQEICPPCEHGAACVPET---------------------
-----------------------GACLCRPGFMGSRCQDACPAGWF----------GPGC
QTQ---CS---CANDGLCHP----VTGRCSCAPGWTGLSCQR----------------AC
DS---------------GHWGPDCSFTCNCSAGHGGCDAVSGLCVCEAGYVG--------
PRCEQRCPQGYFGPG--------CGRQCQ--CEHGAACDHV--SGA--CTCPAGWRGTFC
E---RACPAGFFGVDCG-H----ACDCSAGVPCDPVSGS----CLCPSGRQGPRCAQTCP
AHMFGHNCSQACSCFNGASCDPVHGQ----CRCGPGWTGPTCL---QACPEGLYGEDCQH
SCLCQN-----------------------------------------GGSCDPVSGH---
-CTCPEGWAGL--ACEKECLPG---VFEVGC-P-----HSCGCLNGGLC---DPHTVH-C
LCPAGWTG---DKCQSSCPP--SWFGEACAQRCQ--CPPGAACHHVTGE-------CHCP
PGFTG--PSCEQACPP-----GTFGERCGQQC-------HCPGENQACHPASGT-----C
ACAPGYHG---AGCQQRCPPGRFGP-GCELLCGCLNGGSCDAVTGA---------CRCPA
GFLGTDCSLA--------------------------CPHGRF------------------
-GPGCAY-------VCGCGQGAACDPVTGSCS-------CPPGRTGVHCE-----HGC--
----------------------PQNRFGVNCE------HACSCRNGGLCHA--TNGSC--
------------------------------------------------------------
------------------------------SCGLGWTG----------------------
------------------------------------------------------------
-------PHCEL----------------ACPAGRYGAACSLECS---CHNHGACEP--TS
G----ACRCGPGFYGQACEH----------------------------------------
------------------------------------------------------------
------SCP---------------------------------------------------
---------------------------------PGFHGAGCQQTCQCQHGA---------
-P------------------------------CDPVSGQCLCPAGLHGQ------FCERG
CEP----------------------------------------GSFGEGCGQQCDCE---
-----------LGVP--CDPVTGH----CLCPPGRTGT---TCDLGLLAILPLGSLPDRQ
LPFAGLGAGGNMGKRF-----------------------------WASAR----------
---------------------------------RPALSHVD-RSGTQACP----------
------------SHHPHP---------------------THRLQEGLLRAGLCPALLLW-
-------GWSRLR------------------------------PC---QRAVP--LRGRL
HRAHVPA------GWT-------LPAPGE-----------PVSSP--------GP-SGPT
TR--------------------------------------------------------FP
PDPGSAAA----------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>gi|126309728|ref|XP_001376558.	Monodelphis domestica
--------------------------------MQHPSMLL--------------------
--LLLLLS-SLPLTRGLSCENLP-------------EPCANGGTCLSLAQSQET-CQCAP
G-----FLGDRCQFPDPCQSAKPCQNG---GSCETLFLDSQGTYSSQ---VPSFFCSCPP
GFGGS------------------RCQ--LKDPCLSYPCYHNGRCHVLP------------
-----SGQPRCHCLSGWTGEHCQQQDFCKANPCANGGICLATYPQILCDCPQGFEGNSCQ
--HDVNECFKDSELCPPGATCHNTLGSYKCLCPPGQDGPQCEFHMGPCPARGCQNGGTCQ
LAP-GSTTFHLCLCLPGFTG---QECEVNL-----DD--------CSGHRCQNGGTCQDG
FNT-YTCLCPETWAG-------WDCSEDVD----------ECVTTSSPQCQNGG---TCQ
NTPGSFHCVCVSGW-GGPN---C-------EENLDDCAS--ATCAQGSTCIDRV-GSFRC
LCPPGLT----G------------LLCQLQ-DMCL----SQPC-HPEAQCS--TNPISGA
ILCLCQPGY---SGP------------TCHQ-DLDECQMVHQSFSPCEHGGSCLNTPGSF
N-CLCTPGY----TG-----------------------SRCETDHNECLSQPCHPGSTCL
DLLATFR--CFCPPGFE-GQ---LC--------EVEIDECASEPCQHQG-----------
------------------------ICHDQLSGFLCVCLPGFTG---LHCEEDVDECASSP
CAHGGKCQDQ------------------------------------------------PG
AFHCQCPS-------------GYEGLQ---CQI--------EVDECLS-DPCPPGSTCLD
---------LPGSFS---------------------------------------------
-------CL--CPPNVTGQ---LCEFSL------------CPPSLCPPKWECQTESQ---
---CLCPDGNPS----CHP------------------AKDN-------------------
--------C---TCKNGQ-CQG------SSCVCDVGWTGQ---SCE----------EELG
GCVSE-PCAHGGTCYPQSHGYNCTCPTGYT------------------------------
-----------------------------------------------------------G
---LTCSEEVTK---------CD--SRPCLNGGSCNPTS---------------------
---------------------EGYSCTCLPSYT-----------------------GSHC
QTHKDHCTSVSCLNGGTCVD--RTSTFICFCPMGFKGTYCED-----------KTPP-NC
AD-------------------KPCRNGGTCQDGLEGLH-----CICPHGYTG--------
ERCQNPLDL--------------CA-PNP--CQHNAYCLQS--GSTFQCLCSRGWTGSLC
ELPLSPCQVAALNQGKE-V----SSLCQNGGLCMDNGMSHF--CQCPPGFQGSLCQDKVN
VCELGP-------CQHGATCMTHLNG--YFCQCAPGYHGQNCS-EVDACQSQ----PCHN
-----------------------------------------------HGTCSSVPGGFH-
-CSCPPGFVGL--RCEGDVD---------ECLD-----RPCHPVGTVACH-PLANAFF-C
QCYPGYTG---KRCEEKLDA--------CKSQP---CSHGGTCEVEVGSQLG--FTCHCP
LGFEG--PTCLHGAPS---C-GSHH------C-------HHG---GLCLSSSQSGSIPHC
ACLEGYGG---PDC---LIPPIPQ--GCGSPSPCLHNGSCTESHGVRGPGGSGFHCSCPP
GFLGPRCQTSEA------------EGCKGRGGDGT-CDPNCS------------------
-SPDGGWDG----GDCSLGIPDPWKGCPLHAR-------CWLLFRDGQCH-----PQCNT
EECL---------------------FDGYDCET----PQTCTPAYDQYCRDHFHNGHCEK
G-----------------------------------------------------------
----------------------------CDTAECGWDG----------------------
-----------------------------------------GDCRTAVSNPEAGPSLALL
VVLNPPILDQQL------------FTLARVLSVVLRVGLWVRKD---QEDREMVYP--YP
G----AQAEEELWRNKNNPQQ----------ERTAPPTYLSGKESDSLPA----------
--------------------------------------------GFVVVLGVDSSRCGST
PPAQ--QCPWDPGFMLRFLAAMAAIGALETLLPGPLLVAHPQESS-APPAPQLPWPVFFS
-PVAGVILLILSGLLVLQLIRRRRREHGALWLPPGFSSRTRPRTRPAPRGR---------
-RPPLGEDSIGLKPL-------------KPETEADEDGVVICSGHEEGE--EMYQAEERA
PSPKSQLWPLSGRGQESLQMAMLTPPQ-EPENEAPDVDARGPDGVTPLMSAVCCGGS-EP
RIQEGLCPGPKGTEP--WEPLLGG----GASPQAHTVG---SGETPLHLAARFSRL-PAA
RRLIEAGANPNEPDRMGRTPLHTAVAADAREVCQLLLRNRQTSVDARTEDG-----TTPL
MLAA----RLAVEDLVEELIAAQADVGARDKWGKTALHWAA-AVNNARAASA--------
LLQAGADKDAQDSREQTPLFLTAREGAVEVARLLLQAGAARGL--------RDQTGLGPP
DIARQRGHWDLLTLLEGEGLPESRPSLRHKASLGSAGGAKSSKGAFPRTKTLP--KGGAF
PRGR---------TTSGGSTHGGGAYSGRT-------MSMDMAPH--------GG-AAFP
RSPSVSGGGAPPLRILRSPASMRGALHDPGLLLDRSR------GHTGGWPSDWVALGACG
PTPRTPVPPLCLTPSMDERLLGPPPPGGGRGGLGLVGGEPGGPGEPPGGGEPGGGAGGVP
GGRGKQDIGDILQQIMTITDQSPFPIHFPSTLSVFRHSLNLPIILSCLSIRSSQEEEPVD
PQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIY
HSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVGIIHRKFSAIQMQLKQSTCE
AVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVS---
------------------------------QVSNWFGNKRIRYKKNIGKFQEEANIYAVK
TAVSVTQGGHSRASSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSSSQVESLRHSM
GPGGYGDSLGGGQMYSPREMRANGGWQEAVTPSSVTSPTEGPGSVHSDTSN
>gi|157014182|gb|EDO63447.1|	Anopheles gambiae
----------------FEGDAFIGCSAVPKDTPKDVCYPNPCAENAVCSEHNGAAKCTCI
TPYLGDPYNTGCRPECVLNSDCPSHTACVNQHCRDPCPGVCGTNADCTVANHIPVCECSR
GYVGDPFRGCRREVPPPVAPKDPCASC---PSNSVCRVVGG-----------RPTCSCPE
GYRGTPPACRPECSSSEECPHDRSCINLKCADPCPGLCGINAQCQVINHKPFCSCQRDMI
GNPFEQCYPKPAEPVHPYLPARHPIDPCSPSPCGPYSICRVLDGHPVCSCQISCSGVP--
--PNCRPECLINAECPRDRTCINQRCIDPC-------------------PGTCGMNARCR
VVNHNPI----CSCNAGFIGDPFVQCSPEPIVQQETPMP------CNPSPCGANAICKER
NGA-GSCTCAPEYFGDPYVGCRPECVMNSDCPRTRACINNKCQDPCPGTCGVNA---ECH
VVNHAPSCVCLTGF-IGNPFTECRP-QPENEPVVQPCQP--SPCGPNSVCRVLN-NHAVC
TCKQNYI----GSPPNCRPECVVSSECPLD-KSCVKTKCVDPCPGTCGFNA-RCQVVNHN
PICSCKAGF---TGDPFVRCIPEERRPVVQETPTDPC-----IPSPCGPNSQCKAIGHTA
A-CSCLPNY----IGRAPNCRPECTSNSQCTPMKACINERCGDP---C-PGSCGSNALCT
VQNHQPN--CRCIEGYE-GDPYTSCSPVIIHREPEIVDPCNPSPCGINA-----------
------------------------ECNVRNNAGSCTCVKDYYGDPYHECRPEC--MLSSD
CPNTRACLNN-----------------------------KCVDPCPGMCGLNAECFVMNH
SPSCACMP-------------GYTGNPSQACREIPKQIEHTPIDPCRP-SPCGPYSQCRN
VNEHAVCSCQANYIGSPPACRPECTVSSECAMDKACIKQSCLDPCPGTCGFNARCTVINH
N----PICS--CPSGFTGDPFERCVP-EEKQVVQAEPTNPCLPSPCGPNSQCRAVGNVPA
---CSCLPNYVGRAPNCRPECTINAECSGNLACVNEKCADP-------------------
--------C---PGSCGPNAVCRVIEHSPSCSCQTGYTGDPFSGCTVIPLTPVREE-SRN
PCNPS-PCGSNAVCKERNGAGSCTCLPDYFGDPYSGCRPECVT----------NSDCPRV
RACVNNKCADPCP------------------GVCGIDAECYVVNHSPS---CACRPGYTG
DPFTQCRPPEQPKQNEP-INPCT--PSPCGPNSICRESN---------------------
---------------------GHAVCTCQASFIGTPPNCRPECIVSSECALDKACIGQKC
ND----PCPGTCGQNARCQV--VNHNPICSCSLGFTGDPFVRCVPVEKAPVV-QDPVDPC
VP-------------------SPCGPNSVCRAIGSTPA-----CSCLPNYIG------RA
PNCRPECMLNAECPATLACVNERCTNPCVGSCGINARCTVV--KHNPICECEAGFTGD--
--PFSICTEIIPIRDVEPVNPCNPSPCGANAVCKERNGAGS--CTCMPEYFGDPYTGCRP
ECVQNTDCEKSKACMNNKCRDPCPGVCGLNAECVVQNHSPVCF-----CLEGYTGDPAST
CTLAEIVTERPKTPG-CQPSPCGP-----------------------NSQCREINGHPV-
-CSCLAGYIGTPPMCRPECVVSSECSQDRACVNK-KCVDPCPGTCGAEARCQVVNHNPIC
SCPPGFTGDPFVQCAKKEEQKDITPVNPCVPSP---CGPNSNCRTVGSQP-----ACSCA
ANYIGRPPNCRPECTRDAECPSNLA------CQNEKCVDPCAAGCGLNAVCRVINHKPVC
TCDEGFEGNPLEQCSRILPRKYSKRLTPCTPSPCGPNAECRERNNA-------GACYCLT
GYEGNPYDVF--------------SGCRRECDVNADCPDKLACV----------------
-QYKCVDPCP---GVCGAQALCEIQNHVPTCI-------CPEGTVGDPF------VQCNL
RMAD-------------------------PVTPASPVCDKYTCGPNSICRI--QNGVA--
------------------------------------------------------------
----------------------------VCKCQPDMVG----------------------
-----------------------------------SPPNCRPECQQNSDCEANRACV-NL
KCIDPCPGSCGQNANCNIINHNPICSCAPGFTGDPFTRCYKEIVTTSTTEAPRALC--TP
SPCGPNAECKVIGDREACSCLPGYI-GAPPSCRPE-------------------------
--------------------------------------------CILSTECADNQACIRQ
KCED--PCPGSCGLNAKC--SVSRHTPSCSCDAGFTG---------DPFTGC--QAIIED
VPVL----------------------------------NPCN------------------
-PSPCGAN--------------------AQCREQNGAGACTCIEDHFGN-------PYEG
CRPECVLNSDCPSNRACVRN--------KCQDPCPGT----------------CGQN---
-----------ADCQ--VVNHLPS----CTCFPGYEGDPFRYC--------NIQQREPVQ
EYV--NPCQPSP-----CGPNSQCREVNGQAVCSCLPTYVGSPPGCRPECV-----VSSE
CALN----KACVNQKCVDPCPGTCGTNAR-------------CNVNNHSPIC--------
SCQSGFTGDPFTRCYPIP--------------PPVQDTPIVVRNPCVPSPCGPNSQCRDV
NGSPSCSCL--INYIGS--PPNCRPECTINA------------ECPSNQACMN--EKCRD
PCP----------GSCGINARCNVINH----------TPICTCEE--------GY-TGDP
F-----------------------------------------------------------
-TSCRPMP----------------PP----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>gi|3046867|dbj|BAA25571.1|	Halocynthia roretzi
------------------------------------MLTYKGIIKE--------------
--MFELDMKSVYFIVLVVITRSS----IVESLCTSDAQCKNGGTCQ------SNTCSCTS
SYVGD-TC----EVSSPCIPS-PCLNS---GTCAVTELTAG---------DFSYQCTCQT
GFTGD------------------TCS--QVLYCSPNPCSNGAGCEELS------------
-----NS--------------------------------------FKCTCTSGYYGDTCA
--NDVNEC-DTPDICQNAGTCSNNDGGYS-------------------------------
-----------CSCVAGFEG---NNCEVNI-----DD--------CSGHSCQNGATCADA
VST-YDCHCPAEWTG-------QYCTIDVD----------ECSL--SNNVAKRR---DLQ
QTEGGFTCNCVYGF-TRDD---C-------SENIDDCSN--VACFHNARCIDQA-GTFEC
LCTPGNR-----------------ILCHLD-DACI----SDPC-ARGATCD--TNPITGH
WMCDCPDGW---TDK------------DCSK-DIDECS---LGGNPCEHNGQCNNTDGSF
E-CICVAGY----SG-----------------------PRCETNINECEPNPCRNDATCL
DMIGNFN--CVCMPGFT-GI---IC--------DEDIDECESNPCANGG-----------
------------------------TCIDEVNAYTCSCALGFTG---DDCSQNIDECASTP
CMNKATCIDK---ANAYECECAPGYTGVHCETNID----DCVINPCHYGSCR----DGVN
TFYCDCLL-------------GYEGTK---CQT--------DTNECAS-SPCENGGTCTD
EIGYYTCTCPTGTSGS------SCEINPDDCVGNPCQYGTC---VDGVDDYS--------
-------CS--CTPGYTGE---HCDTDI----------NECDSNPCMNGATCQNEVNNFV
---CQCPPGIMGT--QCSSDI---QECSSNP------CLHEYARRDQHVHCICDAGYQGE
NCETEINECASNPCQHGA-CENKVAQ--FVSHCDAGYTGT---ACE----------IDIN
ECATQ-PCQNGGTCTSGINSYNCACPAKYTG-------VNCETELSPCVPNPCENGATCQ
ESADYLAYVCQCPEGFRGPTCATDINECVN-SPCKNGGGCTNLVPGYQ---CTCSQGFTG
---KDCDTDIDD---------CS--SNPCLNGGQCLDDV--GSYKCLCLPGFEGNNCQEE
VNECASFPCKNGGICTDYV--NSYVCTCLSGFY-----------------------SLDC
EKNIEDCSSSSCMNGGTCVD--GINSYSCSCTANFTGDKCQN-------------AVNNC
AS-------------------LQCQNGGTCYYDSGDPK-----CACVHGYTG--------
THCESLQNL--------------CTGPNI--CKNGGSCVQT--SNTVSCNCLGGYEGTDC
AVPQVSCTVGASLLGIA-V----SDLCLNGGTCHDTSTAHE--CSCVAGFTGSYCDIDID
ECASVP-------CKNGATCNDLINS--YSCICALGYEGATCLTDKDECASS----PCKN
GGTCIDRINSFY--CSCLAGTEGVLCEINEDECEINI-------CLNGGVCIDGIGGFS-
-CQCPSGYEGR--RCQGDVN---------ECLS-----NPCSSPGSLAC-IQGSNSYQ-C
VCDADYTG---SECQIRIGS--------CDINP---CLNDGICTDNSQDITG--YKCQCT
WGYYG--KKCENSYSM---CSANFF------C-------YH------EAPCQDG----TC
ICTENYY-------------------GTNCEKTTAQEGTCSNTCEL---VKGDGICDKEI
GCN---------------------------------------------------------
-VHECEFDG----GDCSLGISILGGKCDKELR-------CWQLYQDGHCD-----EHCNN
EDCL---------------------HDGMDCAT---PVGDCNPKYEKYCNEYYNNDYCDQ
G-----------------------------------------------------------
----------------------------CNNANCGWDG----------------------
-----------------------------------------ADCIKDYPAQYARGFLV-I
RMEGITPEEMRE----------------QEMIFIIEFGKILRSG---IEIISIE------
--------EIFLESSRRRRALLDFDVEMSKTRHRRATDTSATSE----------------
-----------------------------------------------VKVRLDNRNCLL-
-NDD--SCFWEASSAASYVSASASTGTLQVSFDVSTATSQPDETS----DPETPLVYILS
GSVGGVLVLLVAVVLV---RQKRKRENGTLWLPEGF-GVPKKQKRREPIGQDGQDLNLKK
LSKSSQLDPNSSTPFISHWEDGNQKHKQSKYLAQDESLHGSSLPSYTNQSKPNSALSDRE
AHPDVRKWTPQHLQAGGLSELLPSSPLTENGQDLNDIDIRGPDGITPLMVASTRGGGIEV
VSDEESAEGLEEGSENIIANLLTQ----GASLSAQTDR---TGETALHLAARYARAD-AA
KRLLDAGADANMKEQTGRTPLHVAVAADAQGVFQILLRNRATDLNASTNDG-----TTPL
IFAA----RLAVEGMVEELINAQADINAVDSHGKSALHWAA-AVNNIEALTA--------
LLRAGANRDAQTEREETPLFLAAREGSYEAVRVLLDHFANRDV--------TDHMDRLPR
DIANERLHTDIVQLLDE---YNLVRSPNLPSHMDNSPLVHSNSNYISHMKATN--KGKRR
PNGK---------NDTKSSRRGKKKSAGQDS------MESPPGMN--------GNINSHP
MYSSMPLSDG------------------------QSP----------GSNSLSSPATTYS
DSTHSPPISNAGMNPYYQRIISQGNPNGIMENHINIHTPQMTGHKMMQPGRGISGLGLNI
G-----------------------------------------------------------
------------------------------------------------------------
----------------------------QLQTRYNETAMHHPQHSQMAAFQSLGIPQHLI
NNPQHVQMGYRLPDGVRNGEMPFYQPGQPQPSYQPNMQQHYG-QQITSIAHAGPHYLHHT
KVSSRPSVSSSNLYGMEKFPSPPSNSLSPPSDHFSPPSVS--------------------
-----------------ASHVPRTMQETCYETPSPDSVEWSSSPRSDYWSDSIHS---PN
GPSSGPQMHHSGIHQNIHNQNLPSQMRGTGVQMYPPQNPASSVKLQAV---
>gi|115924496|ref|XP_001197427.	Strongylocentrotus purpuratus
------------------------------MADDVLLTTGSCTSLPCQNGGMCFMSGDDT
DYTCVCPPGFSGMNCELATTDAP----TVVNPCMS-EPCQNGAACYSAADSSSFTCLCVA
HFVGV-LCETATQIASPCDSA-PCQNG---GECFMSADESG------------YFCACPM
GYTGD------------------NCE--AASVCDSAPCENGGACFTSA------------
-----DGNS------------------------------------YVCSCQSGFSGTNCE
TVQQVDPC--ESSPCQNGATCSLDGVQYQCICALGFTGINCELVLTPCNADPCLNGATCF
QQDNSGNYL--CVCPTGVTG---TNCESSI-----PAA-------CSSNPCRNEGVCFES
QSSGYFCSCPMGWEG-------TNCEMPSD----------LC-DEAP--CQNGA---VCI
NMQTSYMCQCAAGF-GGDN---C-------ETVLQACAS--SPCQNDAICFDGLNGGYVC
RCLVGYE----G------------ANCETEINACN----SSPC-QNGAICF--EGAYVNE
FVCICPVGW---EGT------------VCDT-PVDLC-----DPSQCQNGATCTNMQTSY
T-CECPAGF----TG-----------------------QNCEDVESPCNAEPCQNDAACF
VSAESTSYLCLCMPGWE-GE---DC--------DMAIDACDPNPCFNGA-----------
------------------------TCNDLQSSFTCTCPDGFGG---ASCETVLVACATNP
CENGATCFESGQSSGGFFCLCEAGWEGSMCEVAIDASISGCTNNPCQNEATCFVSGSGSQ
AYICLCEP-------------GWEGVD---CSQ--------ASNPCQPINPCMNGATCVN
QQTSFSCQCLDGFTGS------MCETALESCSSMPCENGAVCFEASNNNGFF--------
-------CQ--CPTGFTGT---NCENVQ----------MACDLQPCQNGADCFQQETNES
GYYCLCPDGFQGD--NCEVAL---TPCNPDPCRNGAACVED----GTQFMCLCRLGFSGD
LCENVIGACMSEPCLNGAVCFEDVNGENFFCSCTADWQGP---TCA---------EPLQN
NCDPN-PCMNGGTCTSHLNTFQCACPEGFAG-------ALCQLEILPCASNPCQNGATCF
EHANGGTYVCLCVAGFEGIDCEAEIISCSS-DPCLNEATCLELGNGEGHI-CICVPGFEG
---VTCASETPA---------CS--SSPCQNGATCFDQNSGNGYACLCAADFEGTNCEQE
ILGCGSNPCMNGASCFDLSDGSGYACACTNGFE-----------------------GTNC
ENDILACASNPCLNGATCFDSNGGSSYACLCPAGFEGSNCEN-------------EILAC
AS-------------------NPCLNGATCFDSNGGSS---YACLCPAGFEG--------
TNCENEMLA--------------CA-CNP--CMNGATCFDSNGGSSYACLCPAGFEGTNC
ENEILACA---------------SNPCLNGATCFDSNGGSSYVCLCPAGFEGTNCENVAA
ACASNP-------CLEGATCVEDTGDKTYSCICPDGFQGTNCESEILACASN----PCLN
GATCFDHNGGSGYACLCPAGFEGTNCENEILACASSP-------CLNGATCFDHNGGSGY
ACLCPAGFEGT--NCENEIV---------ACAS-----NPC--LNGATCFDSNGGSGYAC
LCPAGFEG---THCENDILA--------CASNP---CLNGATCFDHNGGSG---YVCLCP
AGFEG--TNCENDILA---C-ASSP------C-------LNGAT---CFDSNGG-SSYVC
LCPARFEG---TICENDI--------FACASNPCLNGATCFDHNGD-----SGYACLCPA
GFEGTNC-----------------ENEMQPCESNP-CLNGATCFTQPMGTSYSCLCPMGF
EGTNCEIEL----SVCDSSPCVNNGTCFTHSNGEAYTCVCPTGFEGNNCENISAMPACDS
NPCLNGATCMDREEFSAYGCLCPAGYEGTNCENETLPCASNPCLNGASCFD--SNGGSSY
V-----------------------------------------------------------
----------------------------C-LCPAGFEG----------------------
-----------------------------------------TNCEIEILACSSNPCLNGA
TCFDSNGGSSYA------------CLCPAGFEGTNCENEILACASNPCLNGATCFD--SN
GGSSYVCLCSAGFEGSNCEN----------------------------------------
----------------------------------------------------ETLSCASN
PCLNGATCFDSNGGSSY----------ACLCPPGFEGTNCENETNACVSTPCQNDAVCFN
TALGGYICIC----------------------AEGYDGINCETETLSCASD---------
-PCLNGATCFDSNGGSSYTCLCLAGF--EGTNCENEILACASNPCLNGA---TCFDSNGG
SGYTCLCLAGFEGTN-CENVMLACASN-PCLNGATCFDSNGGSSFVCLCPAGFEGTN---
------CGNVISACG--SNPCLNG----ATCFNGPQGGYMCACAMG----FEGDDCESEM
PVCDSNPCQNGATCFEGAQGNYFCFCPAGFEGLNCELETNACASTPCQNDAVCFNAALGG
YICICAEGYEGINCETEIILCASSPCLSGSTCIEGSGQYVCLCAPGYEGTNCETEIQECI
SNPCQNGATCVDLFDGYV---------CSCAPGWIGNDCVIEIQECLSNPCLNGAICA--
EMVDGYGC---ICFVGWTGDDCGTEVLECLSD-----------PCMNGGTCIENVNGYQC
RCAP---------GWSGTHCETDIMEC----------LSIPCLNG--------G--TCTD
LINGFMCQCA------------------------SGW----------TGPTCNEDIAECA
SNPCSNGATCLDLTNEYSCQCGPGWTGT--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------LCEIEIQECSSQPC--------
-------------------------------------------QNDGTCIDLINAYVCI-
------------------------------CAPGWTGNEC--------------------
-----------------QNDIFECSSDPCLN--GANCIELIDGYQCECTAQFEGV---DC
ESGTFV---------------------------------------------
>gi|47523544|ref|NP_999395.1|	Sus scrofa
--------------------------------MGVVTRLLVGTFLA--------------
--SLALPAQGGVLKKVIRHKRQT----GVNVTLPEESQPVVFNHVYNIKLPVGSQCSVDL
E-----SASGDKDLAAPSEPSESVQEHTVDGENQIVFTHRIN--------IPRRACGCAA
A-----------------------------------------------------------
------------------------------------------------------------
--PDVKELLSRLEELENLVSSLREQCTSGAGC----------------------------
-----------CLQPAE--------GRLDT-----RPF-------CSGRGNFSTEGC---
-----GCVCEPGWKG-------PNCSEP------------EC----PSNCHLRG---QCV
DG----QCVCNEGF-TGED---C---------SQLACP---SDCNDQGKCVNGV-----C
VCFEGYS----G------------VDCSR--ETC-----PVPCSEEHGRCV--------D
GRCVCQEGF---AGE------------DCNE-PL--C------LHNCHGRGRCVEN----
E-CVCDEGF----TG-----------------------EDCGELI--C-PKDCFDRGRCI
NGT------CYCDEGFE-GE---DC-----------GRLACPHGCRGRG-----------
------------------------RCEEG----QCVCDEGFAG---ADCSERR--C-PSD
CHNRGRCLDG--------------------------------------------------
--RCECDD-------------GFEGED---CGE----------------LRCPGGCSGHG
-------RCVNGQ-----------------------------------------------
-------CV--CDEGRTGE---DCSQ-L------------RCPNDCHGRGRCVQGR----
---CECEHGFQGY--DCSEMS----------------CPHD-------------------
--------C----HQHGR-CVN------GMCVCDDGYTGE---DCR------------EL
RCPGD--CSQRGRCVDGR----CVCEHGFAG-------PDCAD-----------------
---------LACP------------------SDCHGRGRCVNGQ-------CVCHEGFTG
---KDCGQRR-----------C---PGDCHGQGRCVDGQ---------------------
-------------------------CVCHEGFT-----------------------GLDC
GQR---SCPNDCSNWGQCVS------GRCICNEGYSGEDCSQ-----------VSPPKDL
IV-------------------TEVTEETVNLAWDNEMRVTEYLIVYTPTHEDGLEMQFRV
PGDQTSTTIRELEPGVEYFIRVFAILENKKSIPVSARVATY--LPTPEGLKFKSIKETSV
EVEWDPLDIAFETWEII-FRNMNKEDEGEITKSLRRPETTYRQTGLAPGQEYEISLHIVK
NNTRGPGLKRVTTTRLDAPSQIEAKD-VTDTTALITWFKPLAEIDGIELTYGIKDVPGDR
TTIDLTHEENQYSIGNLKPDTEYEVSLISRRA---------------DMSSNPAKETFTT
GLDAPRNLRRI---SQTDNSITLEWRNGKAAADT-YRIKYAPISGGDHAEVEVPRSPQ-T
TTKATLTG---LRPGTEYGIGVSAVKGDKESDP---ATINAATDLDPPKDFRVSELKESS
LTLLWRTPLAKFDRYR-----LNYG------L-------PSGQPVEVQLPRNAT-----S
YILRGLE----PGQEYTILLTAEK--GRHKSKPARVKASTAGEPEI--------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------GNL
SVSDITPESFSL------------SWTATEGAFETFTIEIIDSN---RFLETMEYN--IS
G----AERTAHISGLRPGNDFIVYL-----------------------------------
--------------------------------------------------------SGLA
PGIQ--TKPISATATTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDSFVLKIRDTKKQS
EPLEITLLASERTRDITGLREATEYEIELYGISSGKRSQPVSAIATTAMGS---------
-PKEITFSDITENSATVSW---------MVPTAQVESFRITYVPITGGA---PSVVTVDG
TKTQTRLLRLLPGVE-YLVSVIAVKGF-EESEPVSGTLTTALDGPSGLVTANITDSE---
-----------ALAM--WQPAIAPVDHYVISYTGDRVPEITRTVSGNTVEYALTNLEPAT
EYTLRIFAEKGPQKSSTITTKFTTDLDSPRDLTATEVQSETALLTWRPPRA-----SVTG
YLLV----YESVDGTLKEVVVGPETTSYSLSGLSPSTHYTA-RIQALNGPLR--------
SKMSQTVFTTIGLLYPFP---------RDCSQAMLNGDTTSGLYTIYVNNDKAQKLEVFC
DMTSDSGGW--IVFLRR---KNGRE------------------DFYRNWKAYA--AGFGD
LKEE---------FWLGLDALSKITAQGQYE------LRVDLRDH--------GE-TAYA
VYDRFSVGDA------------------------RTR--------------YKLKVEGYS
GTAGDSMA----------------YHNG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------RSFSTFDK--------
-------------------------------------------DTDSAITNCALSY----
------------------------------KGAFWYKNCH--------------------
-----------------RVNLMGRYGDNS----HSQGVNWFHWKGHEYSIQFAEM---KL
RPSNFRNLEGRRKRA------------------------------------
>gi|47229848|emb|CAG07044.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---DIDECQVHNGGCQH--RCVNTRGSYYCECHPG-----------------------SR
LHVDGRT----CLAVHS--------CAISN-----GG--------CEHY-CVQQSSTH--
----FLCRCKPNY----------VLAEDRK----------HCALQNPCAVQNGGCMHDCR
LDGTRPHCVCRVGFILAEDRKTC--------QDIDECQTEASNCAHG--CHNTL-GSYVC
VCNAAYELGSDG------------KQCYRI-EMEI----VNSCENNNGGCSHHCQHSTGG
PVCSCNHGYRLDNDL------------KTCI-DVDEC----AEQSSCCEQD-CINYPGGY
E-CYCSAGYRLSSDG-----------------------CNCDDVD-ECVAVNGGCEHTCQ
NSAGSFQ--CFCRRGFRLDEDRQSC---------IPLEDVFEALSSGGA--TEFPLVQPQ
LTLVQDYSLPLERYDDYEDDEGELRAESNLAE-KFVCLDDTFG---NDCSLTC-----DD
CSNGGKCNQW--------------------------------------------------
KSGCDCPDGWTGLICNQTCPEGFFGKN---CSFP---------------SKCKNGGSCDP
VTG--SCRCPPGVSGEF-------------------------------------------
-------CQDGCPKGFYGK---LCNK--------------RC--NCANNGRCHRTYGA--
---CLCDPGLYGR--FCHLSC--------PKWAFGPGCSEE-------------------
--------C-RCVQQNTLECHRRF----GTCVCKPGYKGS---TCK----EECDPGTFGA
RCESRCACPAGVSCHHVSGACQRKCPPGLHG-------ESCDQ-----------------
----------DCPEGTFG-------------AGCAHPCNCSGAVCDPVTGGCKCPAGTSG
---EHCENLCPEGSWGP---GCTQTCPVCENGGVCHKHN---------------------
-----------------------GSCICPPGFMGRLCQNTCPSGRF----------GQGC
QMK---CI---CENNARCDV----ASGRCTCAPGWTGHNCRKGNDAAVKQSPLQVPAADA
TFSFCVKRDVSFAACDAGRWGTDCAETCDCRNGDGSCDPVTGQCNCEAGYTG--------
DKCQQKCPTGMFGFG--------CRHRCQ--CDNKALCDHV--SGA--CTCQSGWTGTFC
E---KPCPRGFYGLDCQ-E----KCLCLNGGSCNHVSGH----CSCPAGWIGRSCNLTCP
PGSYGGGCNQTCSCRNSGICHPASGQ----CACTPGWTGPNCT---EECPAGFYGADCLQ
RCLCQN-----------------------------------------GATCNKSNGT---
-CACTSGWTGA--ACELECDVG---QFGADCQ------QQCHCENGGQCDRQTGR----C
SCSGGWIG---ERCERACLP--GSYGTDCVQRCS--CPRGASCHHISGE-------CGCP
PGLMG--NGCEQTSGR-------------------------------------------C
YCAPGFDG---PRCDRICKEGRYGP-GCEGECRCENGGRCVPSTGA---------CECPP
GFIGARCHTA--------------------------CPAGHF------------------
-GPDCA-------GAAACGEGAPTDPVSGRCL-------CGPGRRGEDCG-----HDC--
----------------------PPGWFGVGC------LHRCNCSHGNRCDA--ATGNC--
------------------------------------------------------------
------------------------------TCGLGWTG----------------------
-----------------------------------------ARCDEGEADFFFNVLLRFV
CCV----LNCGV------------FLVSECPAGHFGANCQLRCD---CQNNSTCDR--VT
G----TCRCAAGHYGRQCEH----------------------------------------
-----------------------------------------------------------C
ACKQ--TCP---------------------------------------------------
---------------------------------PGLYGPSCQLQCDCANGA---------
-------------------------------FCHPATGQCMCPAGYRGA-----------
-----RCHRLCE------------------------------QGTYGVGCAQVCNCG---
-----------GAAA--CDHVTGR----CLCSSGKTGP---RCDLGKLHTHS--------
------------------------------------------------------------
---------------------------------TPFLLYSG-------------------
---------------PFP---------HSCV---LASDCRENFY---------GP-----
DCAETC-------------------------------------ECENGAQCDP--RNGRC
SCRH---------SWIG-----------------------PACQE--------G------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------
>gi|114626357|ref|XP_001156720.	Pan troglodytes
--------------------------------MGAMTQLLAGVFLA--------------
--FLALATEGGVLKKVIRHKRQS----GVNATLPEENQPVVFNHVYNIKLPVGSQCSVDL
E-----SASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRIN--------IPRRACGCAA
A-----------------------------------------------------------
------------------------------------------------------------
--PDVKELLSRLEELENLVSSLREQCTAGAGC----------------------------
-----------CLQPAT--------GRLDT-----RPF-------CSGRGNFSTEGC---
-----GCVCEPGWKG-------PNCSEP------------EC----PGNCHLRG---RCI
DG----QCICDEGF-TGED---C---------SQLACP---SDCNDQGKCVNGV-----C
ICFEGYA----G------------ADCSH--EIC-----PVPCSEEHGTCV--------D
GLCVCHDGF---AGD------------DCNK-PL--C------LNNCYNRGRCVEN----
E-CVCDEGF----TG-----------------------EDCSELI--C-PNDCFDRGRCI
NGT------CYCEEGFT-GE---DC-----------GKLTCPHACHGQG-----------
------------------------RCEEG----QCVCDEGFAG---VDCSEKR--C-PAD
CHNRGRCVDG--------------------------------------------------
--RCECDD-------------GFTGAD---CGE----------------LKCPNGCSGHG
-------RCVNGQ-----------------------------------------------
-------CV--CDEGYTGE---DCSQ-L------------RCPNDCHSRGRCVEGK----
---CVCEQGFKGY--DCSDMS----------------CPND-------------------
--------C----HQHGR-CVN------GMCVCDDGYTGE---DCR------------DR
QCPRD--CSNRGLCVDGQ----CVCEDGFTG-------PDCAE-----------------
---------LSCP------------------NDCHGRGRCVNGQ-------CVCHEGFMG
---KDCKEQR-----------C---PSDCHGQGRCVDGQ---------------------
-------------------------CICHEGFT-----------------------GLDC
GQR---SCPSDCNNLGQCVS------GRCICNEGYSGADCSE-----------VSPPKDL
VV-------------------TEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRV
PGDQTSTIIRELEPGVEYFIRVFAILENKKSIPVSARVATY--LPAPEGLKFKSIKETSV
EVEWDPLDIAFETWEII-FRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVK
NNTRGPGLKRVTTTRLDAPSQIEVKD-VTDTTALITWFKPLAEIDGIELTYGIKDVPGDR
TTIDLTEDENQYSIGNLKPDTEYEVSLISRRG---------------DMSSNPAKETFTT
GLDAPRNLRRV---SQTDNSITLEWRNGKAAIDS-YRIKYAPISGGDHAEVDVPKSQQ-A
TTKTTLTG---LRPGTEYGIGVSAVKEDKESNP---ATINAATELDTPKDLQVSETAETS
LTLLWKTPLAKFDRYR-----LNYS------L-------PTGQWVGVQLPRNTT-----S
YVLRGLE----PGQEYNVLLTAEK--GRHKSKPARVKASTEQAPEL------ENLTVTEV
GWDGLRLNWTAADQAYEHFIIQVQEANKVEAAQNL-TVPGSLRAVDIPGLKAATPYTVSI
YGVIQGYRTPVLSAEASTGKTPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADT
VEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV
TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSVEIPGLRAGTPYTI
TLHGEVRGHSTRPLAVQVVTEELPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEV
NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNL
NVSDITPESFNL------------SWTATDGIFETFTIEIIDSN---RLLETVEYN--IS
G----AERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPY
GFTVSWMASENAFDSFLVMVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT
QGHQ--TKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQS
EPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQPVSAIATTAMGS---------
-PKEVIFSDITENSATVSW---------RAPTAQVESFRITYVPITGGT---PSMVTVDG
TKTQTRLVKLIPGVE-YLVSIIAMKGF-EESEPVSGSFTTALDGPSGLVTANITDSE---
-----------ALAR--WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPAT
EYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRA-----SVTG
YLLV----YESVDGTVKEVIVGPDTTSYSLADLSPSTHYTA-KIQALNGPLR--------
SNMIQTIFTTIGLLYPFP---------KDCSQAMLNGDTTSGLYTIYLNGDKAQALEVFC
DMTSDGGGW--IVFLRR---KNGRE------------------NFYQNWKAYA--AGFGD
RREE---------FWLGLDNLNKITAQGQYE------LRVDLRDH--------GE-TAFA
VYDKFSVGDA------------------------KTR--------------YKLKVEGYS
GTAGDSMA----------------YHNG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------RSFSTFDK--------
-------------------------------------------DTDSAITNCALSY----
------------------------------KGAFWYRNCH--------------------
-----------------RVNLMGRYGDNN----HSQGVNWFHWKGHEHSIQFAEM---KL
RPSNFRNLEGRRKRA------------------------------------
>gi|156229767|gb|AAI51844.1|	Homo sapiens
--------------------------------MGAMTQLLAGVFLA--------------
--FLALATEGGVLKKVIRHKRQS----GVNATLPEENQPVVFNHVYNIKLPVGSQCSVDL
E-----SASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRIN--------IPRRACGCAA
A-----------------------------------------------------------
------------------------------------------------------------
--PDVKELLSRLEELENLVSSLREQCTAGAGC----------------------------
-----------CLQPAT--------GRLDT-----RPF-------CSGRGNFSTEGC---
-----GCVCEPGWKG-------PNCSEP------------EC----PGNCHLRG---RCI
DG----QCICDDGF-TGED---C---------SQLACP---SDCNDQGKCVNGV-----C
ICFEGYA----G------------ADCSR--EIC-----PVPCSEEHGTCV--------D
GLCVCHDGF---AGD------------DCNK-PL--C------LNNCYNRGRCVEN----
E-CVCDEGF----TG-----------------------EDCSELI--C-PNDCFDRGRCI
NGT------CYC-EGFT-GE---DC-----------GKPTCPHACHTQG-----------
------------------------RCEEG----QCVCDEGFAG---VDCSEKR--C-PAD
CHNRGRCVDG--------------------------------------------------
--RCECDD-------------GFTGAD---CGE----------------LKCPNGCSGHG
-------RCVNGQ-----------------------------------------------
-------CV--CDEGYTGE---DCSQ-L------------RCPNDCHSRGRCVEGK----
---CVCEQGFKGY--DCSDMS----------------CPND-------------------
--------C----HQHGR-CVN------GMCVCDDGYTGE---DCR------------DR
QCPRD--CSNRGLCVDGQ----CVCEDGFTG-------PDCAE-----------------
---------LSCP------------------NDCHGRGRCVNGQ-------CVCHEGFMG
---KDCKGQR-----------C---PSDCHGQGRCVDGQ---------------------
-------------------------CICHEGFT-----------------------GLDC
GQH---SCPSDCNNLGQCVS------GRCICNEGYSGEDCSE-----------VSPPKDL
VV-------------------TEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRV
PGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATY--LPAPEGLKFKSIKETSV
EVEWDPLDIAFETWEII-FRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVK
NNTRGPGLKRVTTTRLDAPSQIEVKD-VTDTTALITWFKPLAEIDGIELTYGIKDVPGDR
TTIDLTEDENQYSIGNLKPDTEYEVSLISRRG---------------DMSSNPAKETFTT
GLDAPRNLRRV---SQTDNSITLEWRNGKAAIDS-YRIKYAPISGGDHAEVDVPKSQQ-A
TTKTTLTG---LRPGTEYGIGVSAVKEDKESNP---ATINAATELDTPKDLQVSETAETS
LTLLWKTPLAKFDRYR-----LNYS------L-------PTGQWVGVQLPRNTT-----S
YVLRGLE----PGQEYNVLLTAEK--GRHKSKPAHVKASTEQAPEL------ENLTVTEV
GWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNL-TVPGSLRAVDIPGLKAATPYTVSI
YGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADT
VEAAQNLTVPGGLGSTDLPGLKAATHYTITIRGVTQDFSTTPLSVGVLTEEVPDMG----
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------NL
TVTEVSWDALRL------------NWTTPDGTYDQFTIQVQEAD---QVEEAHNLT--VP
G----SLRSMEIPGLRAGTP----------------------------------------
---------------------------------------------------YTVTLHGEV
RGHS--TRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVE
AAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAMGS---------
-PKEVIFSDITENSATVSW---------RAPTAQVESFRITYVPITGGT---PSMVTVDG
TKTQTRLVKLIPGVE-YLVSIIAMKGF-EESEPVSGSFTTALDGPSGLVTANITDSE---
-----------ALAR--WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPAT
EYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRA-----SVTG
YLLV----YESVDGTVKEVIVGPDTTSYSLADLSPSTHYTA-KIQALNGPLR--------
SNMIQTIFTTIGLLYPFP---------KDCSQAMLNGDTTSGLYTIYLNGDKAQALEVFC
DMTSDGGGW--IVFLRR---KNGRE------------------NFYQNWKAYA--AGFGD
RREE---------FWLGLDNLNKITAQGQYE------LRVDLRDH--------GE-TAFA
VYDKFSVGDA------------------------KTR--------------YKLKVEGYS
GTAGDSMA----------------YHNG--------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------RSFSTFDK--------
-------------------------------------------DTDSAITNCALSY----
------------------------------KGAFWYRNCH--------------------
-----------------RVNLMGRYGDNN----HSQGVNWFHWKGHEHSIQFAEM---KL
RPSNFRNLEGRRKRA------------------------------------
