>gi|114616821|ref|XP_001140842.	Pan troglodytes
------MRLSSLLALLRPALPLILGLSLGCSLSLLRVSWIQGEGEDPCVEAVGDRG----
-------GPQNPDS------RARLDQND---EDFKPRIVPYYR-DPNKPYKKV-----LR
TRYIQTELGSRE------RLLVAVLTSRATLSTLAVAVNRTVAHHFPRLLYFTG-QRGAR
APAGMQ-VVSH----GDERPAWLMSETLRHLHTHFGADYDWFFIMQDDT-----YVQAPR
LAALAGHLSINQD--LYLGRAEEFI----------------------GAG-EQARY----
---CHGGFGYLLSRSLLLRLRPHLDGCRGDILSARPDEW---LG-RCLIDSLGVG-CVSQ
HQ--------GQQYRSFELAKNRDPEKE-----GSSAFLSAFAVHPVSEGTLMYRLHK--
----RFSALELERAYSEIEQLQAQIRNLTVLTPEGE-AGLSWPVGLPA---PFTP-----
---HSRFEVLGWDYFTEQHTFSCADG----APKCPLQGA---SRADVGDALETALEQLNR
RYQPRLR----------FQKQRLLNGYRRFDPARGMEYTLDLLLE--------CVTQRGH
RRA---LARRVSLLRPLSRVE-----ILP------------------------------M
PYV---T-----E--ATRVQLVLPLLVAEAAAAPAFLEAFAANVLEPREH-ALLTLLLVY
GPREGGRGA-PNPFLGVKAAAAELERRYP--GTRLA-WLAVRAE----------------
-------APSQVRLMDVVS-KKHPV------DTLFFLTTVWTRPGPEVLNRCRMNAISGW
QAFFPVHFQEFNPALSPQRSPPGPPGAGPDPPSPPGADPSRGAPIGGRFDRQASAEGCFY
NADYLAARARLAGE-LAGQEEEEALEGLE--------------VMDVFLRFSG-LHLFRA
VEPGLVQKFSLRDCSP-----RLSEELYHRCRLSN----LEGLGGRAQLAMALFEQEQAN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|37181931|gb|AAQ88769.1|	Homo sapiens
------MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWV----EEPCGPGPPQPGDSEL
PPRGNTNAARRPNSVQPGAEREKPGAGEGAGENWEPRVLPYHPAQPGQAAKKA-----VR
TRYISTELGIRQ------RLLVAVLTSQTTLPTLGVAVNRTLGHRLERVVFLTG-ARGRR
APPGMA-VVTL----GEERPIGHLHLALRHLLEQHGDDFDWFFLVPDTT-----YTEAHG
LARLTGHLSLASAAHLYLGRPQDFI----------------------GGEPTPGRY----
---CHGGFGVLLSRMLLQQLRPHLEGCRNDIVSARPDEW---LG-RCILDATGVG-CTGD
HE--------GVHYSHLELS-PGEPVQE-----GDPHFRSALTAHPVRDPVHMYQLHK--
----AFARAELERTYQEIQELQWEIQNTSHLAVDGD-RAAAWPVGIPA---PSRP-----
---ASRFEVLRWDYFTEQHAFSCADG----SPRCPLRGA---DRADVADVLGTALEELNR
RYHPALR----------LQKQQLVNGYRRFDPARGMEYTLDLQLE--------ALTPQGG
RRP---LTRRVQLLRPLSRVE-----ILP------------------------------V
PYV---T-----E--ASRLTVLLPLAAAERDLAPGFLEAFATAALEPGDAAAALTLLLLY
EPRQAQRVAHADVFAPVKAHVAELERRFP--GARVP-WLSVQTA----------------
-------APSPLRLMDLLS-KKHPL------DTLFLLAGPDTVLTPDFLNRCRMHAISGW
QAFFPMHFQAFHPGVAP-----------PQGPGPPE--LGRDT---GRFDRQAASEACFY
NSDYVAARGRLA---AASEQEEELLESLD--------------VYELFLHFSS-LHVLRA
VEPALLQRYRAQTCSA-----RLSEDLYHRCLQSV----LEGLGSRTQLAMLLFEQEQGN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|109101151|ref|XP_001104808.	Macaca mulatta
------MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWV----EEPCGPGPPQPGDSEL
PPRGNTNAARRPNSVQPGAEREKPGTGAGAGENWEPRVLPYHPAQPGQAAKKA-----VR
TRYISTELGIRQ------RLLVAVLTSQATLPTLGVAVNRTLGHRLERVVFLTG-ARGRR
APPGMA-VVTL----GEERPIGHLHLALRHLLEQHGDDFDWFFLVPDTT-----YTEAHG
LARLTGHLSLASAAHLYLGRPQDFI----------------------GGEPTPGRY----
---CHGGFGVLLSRMLLQQLRPHLEGCRNDIVSARPDEW---LG-RCILDATGVG-CTGD
HE--------GVHYSHLELS-PGEPVQE-----GDLRFRSALTAHPVRDPVHMYQLHK--
----AFARAELERTYQEIQELQWEIQNTSRLAVDGD-RAAAWPVGIPA---PSRP-----
---ASRFEVLRWDYFTEQHAFSCADG----SPRCPLRGA---DRADVADVLGTALEELNR
RYHPALR----------LQKQQLVNGYRRFDPARGMEYTLDLQLE--------ALTPQGG
RRP---LTRRVQLLRPLSRVE-----ILP------------------------------V
PYV---T-----E--ASRLTVLLPLAAAERDLAPGFLEAFATAALEPGDAAAALTLLLLY
EPRQAQRAAHADVFAPVKAHVAELERRFP--GARVP-WLSVQTA----------------
-------APSPLRLMDLLS-KKHPL------DTLFLLAGPDTVLTPDFLNRCRMHAISGW
QAFFPMHFQAFHPAVAP-----------PQGPGPPE--LGRDT---GRFDRQAASEACFY
NSDYVAARGRLA---AASEQEEELLESLD--------------VYELFLHFSS-LHVLRA
VEPALLQRYRAQTCSA-----RLSEDLYHRCRQSV----LEGLGSRTQLAMLLFEQEQGN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|118095963|ref|XP_413889.2|	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MECRTWSKSIPGKVEFFS-SEGSD
TSIPIP-IVPLPGVDDSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDV-----YIKGDK
LENFLRSLNSSEP--LFLGQTGLGTTEEMGK----------------LALEPGENF----
---CMGGPGVIMSREVLRRMVPHIGECLREMYTTHEDVE---VG-RCVRRFAGVQ-CVWS
YEMQ------QLFYENYEQNKKG-YIRD----LRNSKIHRAITLHPNKNPPYQYRLHS--
----YMLSRKIAELRHRTVQLHREIVLMSKYSNTEV-HKEDLQLGMPPSFMRFQP-----
---RHREEILEWEFLTGKYLYSGADG---QPPRRGMDSS---QREALDDIVMQVMEMINA
NAKTRGRI---------IDFKEIQYGYRRVNPMYGAEYVLDLLLL--------YKKHKGK
KMT-VPVRRHAYLQQTFSKIQ-----FMEHEEMDAKELASKINQDSGSLSFLSNSLKMFV
PFQLSRSRVERKELKDQKINILIPL-SGRFDMFARFMGNFEKTCLIPNQN-VKLVVLLFN
SNSNPDRAK-----------QIDLMREYRSKYPKAD-MQVLPVS----------------
------GEFSRALALEVGS-SQFQN------ESLLFFCDVDLVFTTEFLQRCRANTVLGQ
QVYFPIIFSQYDPKIVY----------SGKVPSDNHFAFTQKT---GFWRNYGFGITCIY
KGDLLRAGG------FDVSIQGWGLEDVD--------------LFNKVIQAG--LKTFRS
QEIGVVHVHHPVFCDP-----NLDPKQYKMCLGSK----ASTYGSTQQLAEIWFEKNDPS
FGKSSNTNGSVRTA----------------------------------------------
------------------------------------------------------------
-----------------
>gi|48526514|ref|NP_001001566.1	Mus musculus
------MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWV----EEPCGPGPPQPGDSEL
PPRGNTNAARRPNSVQPGSERERPGAGAGTGESWEPRVLPYHPAQPGQATKKA-----VR
TRYISTELGIRQ------KLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTG-ARGRR
TPSGMA-VVAL----GEERPIGHLHLALRHLLEQHGDDFDWFFLVPDAT-----YTEAHG
LDRLAGHLSLASATHLYLGRPQDFI----------------------GGDTTPGRY----
---CHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEW---LG-RCILDATGVG-CTGD
HE--------GMHYNYLELS-PGEPVQE-----GDPRFRSALTAHPVRDPVHMYQLHK--
----AFARAELDRTYQEIQELQWEIQNTSRLAADGE-RASAWPVGIPA---PSRP-----
---ASRFEVLRWDYFTEQYAFSCADG----SPRCPLRGA---DQADVADVLGTALEELNR
RYQPALQ----------LQKQQLVNGYRRFDPARGMEYTLDLQLE--------ALTPQGG
RWP---LTRRVQLLRPLSRVE-----ILP------------------------------V
PYV---T-----E--ASRLTVLLPLAAAERDLASGFLEAFATAALEPGDA-AALTLLLLY
EPRQAQRAAHSDVFAPVKAHVAELERRFP--GARVP-WLSVQTA----------------
-------APSPLRLMDLLS-KKHPL------DTLFLLAGPDTVLTPDFLNRCRMHAISGW
QAFFPMHFQAFHPAVAP-----------PQGPGPPE--LGRDT---GHFDRQAASEACFY
NSDYVAARGRLV---AASEQEEELLESLD--------------VYELFLRFSN-LHVLRA
VEPALLQRYRAQPCSA-----RLSEDLYHRCRQSV----LEGLGSRTQLAMLLFEQEQGN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|108869937|gb|EAT34162.1|	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
---------------------------------MVRMAGSK---LLARLLLLIS------
------------------------------------------------------------
SVTLVSLLALTR------------------------------------------------
---CGLG-GLI---------------ATENGFSNGGSAS---LGERSEENLKEVAKLTAE
IK--------ALKLQILQLKNVQ-----------------PVELLPNGTGLTSGGILN--
-------SPQTPTIHDCSAFIRRQV------------GSAEILHGLPL------------
---NNEYELIPFNHFTFSRVYPIELGLGKRVVEKPI-GY---KRRDILGALNKAIETLNR
NITTNMMK---------YTLDDFTEGIYRNEPTTGTQYELYFRTKEVNKSASSSGQHHDH
GNH---GTTKLIVMRPFAPLQ-----TIQ------------------------------M
EAFPKQQ-----E--KELIHIILPL-SGRTSTFQSFMDKYVKIALKHDKR-VHLTVIYFG
EDGLSEARS-------------IMSRNSG--GNSSN-LKLLALN----------------
------ETFSRAKALRVGAEKVWSSNVNKDKDVLLFMCDVDIVFSAKFLDRCRWNAKPNR
KVYYPVVFSLYNPHVVYTLQ------GKEVPPETDQLLISKDS---GFWRDFGYGMTCQY
RSDFLKVRG------FDEEIIGWGGEDVM--------------LYRKYVRSH--IKVIRA
TDPGIFHIWHPKICTGVSAGQKLSVDQYRACIRSR----ALNEASHAQLGFLAFRDDIVA
NEGKILS-----------------------------------------------------
------------------------------------------------------------
-----------------
>gi|149408730|ref|XP_001506710.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MSSQ
MQ--------QLFYENYEQNKKG-YIRD----LHNSKIHRAITLHPNKNPPYQYRLHS--
----YLLSRKIAELRHRTIQLHREIVLMSKYSNTEI-HKDDLQLGIPPSFMRFQP-----
---RQREEILEWEFLTGKYLYSAAEG---QPPRRGMDSS---QKEALDDIVMQVMEMINA
NAKTRGRI---------IDFKEIQYGYRRVNPMYGAEYILDLLLL--------YKKHKGK
KMT-VPVRRHAYLQQTFSKIQ-----FMEHEEMDAKELANKINQESGSLSFLSNSLKMFV
PFQLPGSKSEHKEPKDKKINILIPL-SGRFDMFVRFMGNFEKTCLIPNQN-VRLVVLLFN
SDSNPDKAK-----------QVELMREYHVKYPKAD-MQILPVS----------------
------GEFSRALALEVGS-SQFNN------ESLLFFCDVDLVFTAEFLQRCRANTVLGQ
QIYFPIIFSQYDPKIVY----------SGKVPSDNHFAFTQKT---GFWRNYGFGITCIY
KGDLVRAGG------FDVSIQGWGLEDVD--------------LFNKVVQAG--LKTFRS
QEVGVVHVHHPVFCDP-----NLDPKQYKMCLGSK----ASTYGSTQQLAEIWLEKNDPS
YGKSSNNNGSVXXXKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTY
GSTQQLAEIWLEKNDPSYGKSSNNNGSRKENRSGNQETWVPIPVLPVGAMPTAMKFSDRR
ITDGFPHDEGPSAHSEK
>gi|126341056|ref|XP_001363991.	Monodelphis domestica
------MRLGSLLALLRPALPLILGLSLGCSLSLLRVSWIQGEGDDPCVEALGELG----
-------GSRKLDS------RIHLGQSD---EDFKPRIVPYYR-DPNKPYKKV-----LR
TRYIQTELGSRE------RLLVAVLTSRATLSTLAVAVNRTVAHHFPRLLYFTG-QRGAR
APAGMQ-VVSH----GDERPAWLMSETLRHLHTHFGADYDWFFVMQDDT-----YVQAPR
LAALAGHLSINQD--LYLGRAEEFI----------------------GAG-EQARY----
---CHGGFGYLLSRSLLLRLRPHLDGCRGDILSARPDEW---LG-RCLIDSLGIG-CVSQ
HQ--------GQQYRSFELAKNRDPEKE-----GSSAFLSAFAVHPVSDGTLMYRLHK--
----RFSALELDRAYSEIEQLQAQIRNLTVLTPEGE-AGLSWPVGLPA---PFTP-----
---RSRFEVLGWDYFTEQHIFSCTDG----APKCPLRGA---SRADVGDAVETALEQLNR
RYQPRLR----------FRKQRLLNGYRRFDPARGMEYTLDLLLE--------AVTQRGH
RRA---LARRVSLLRPLSRVE-----ILP------------------------------M
PYV---T-----E--ATRVQLVLPLLPTEAAAAPAFLEAFAAGVLEPREH-ALLTLLLVY
GPREGGRGA-PDPFAGVKASATELERRHP--GTRLA-WLAVRAE----------------
-------APSQVRLMDVVS-KKHPV------DTLFFLTTVWTRPGPDVLNRCRMNAISGW
QAFFPVHFQEFNPVLAPVKSPPGPPGAGPDPPSPAGPDQPRGASAGGRFDRQASSEGCFY
NADYLAARARLAGE-LAGQEEEEALEGLE--------------VLDVFLRFSG-LHLFRA
VEPGLVQRFSLRDCSP-----RLSEELYHRCRLSN----LEGLGSRAQLAMALFEQEQAN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|149706972|ref|XP_001504714.	Equus caballus
------MRLSSLLALLRPALPLILGLSLGCSLSLLRVSWIQGEGEDPCVEAVGEPG----
-------GPQNPDS------RTRLDQSD---EDFKPRIVPYYR-DPNKPYKKV-----LR
TRYIQTELGSRE------RLLVAVLTSRATLSTLAVAVNRTVAHHFPRLLYFTG-QRGAR
TPAGMQ-VVSH----GDERPAWLMSETLRYLHTHFGADYDWFFIMQDDT-----YVQAPR
LAALAGHLSINQD--LYLGRAEEFI----------------------GTG-EQARY----
---CHGGFGYLLSRSLLLRLRPHLDGCRGDILSARPDEW---LG-RCLIDSLGIG-CVSQ
HQ--------GQQYRSFELAKNRDPEKE-----GSSAFLSAFAVHPVSEGTLMYRLHK--
----RFSALELERAYSEIEQLQAQIRNLTVLTPEGE-AGLSWPIGLPA---PFTP-----
---HSRFEVLGWDYFTEQHTFSCADG----APKCPLQGA---SRADVGDAVETAMEQLNR
RYQPRLR----------FQKQRLLNGYRRFDPARGMEYTLDLLLE--------AVTQRGH
RRA---LARRVSLLRPLSRVE-----ILP------------------------------M
PYV---T-----E--ATRVQLVLPLLVAEAAAAPAFLEAFAASVLEPREH-ALLTLLLVY
GPREGARGA-PDPFLGVKAAAAELERRYP--GTRLA-WLAVRAE----------------
-------APSQVRLMDVVS-KKHPV------DTLFFLTTVWTRPGPEVLNRCRMNAISGW
QAFFPVHFQEFNPALAPQRSPPGAPGAGPDPPSPPGADPSRGASVGGRFDRQASAEGCFY
NADYLAARARLAGE-LAGQEEEEALEGLE--------------VMDVFLRFSG-LHLFRA
VEPGLVQKFSLRDCSP-----RLSEELYHRCRLSN----LEGLGGRAQLAMALFEQEQAN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|115696733|ref|XP_784351.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------MVFRTPSIRTLIK------
--AGLL--------------------------------------------------LCIA
FLLLVAKLETCTN-----------------------------------------------
----TISDGRLAVRDLLAQAQPF---AANGEMDRKEDCM---VA-LSEQEERHRTEIAAL
KQ--------QIVDLKTELTKYVENIQQ---------LEEPM---AAGEAAATARLAK--
----YFDR---EQGRELLEHMQKQMGKIERHRPL--------------------------
---RDEYDVVPFGSLTSKLVYSMEQGLSKRPSQRP-KGD---RKEELVEAVYFAIDELNK
KKETSTD----------FSIENFVDGIYRTDRTVGTFYNLVF---------------RGM
HEN---YYYSMQLLRPFAPIQ-----KYK------------------------------S
QIV--DT-----S--RIVINIIMPL-SGRIEKFRTFMERFQTVVLETKIH-VFLTIVYFG
NMGLPEIHH-------ILEEVTEPFRFHN--------YKIITLS----------------
------GEFSRGRGLEEGV-RSWDGS-----DVLMFFCDVDIAFNREFLEHCRYYTIAGR
TVYYPMVFSLYNPEIVYSTR-------DQIPPESNMFHIHKDS---GFWRDFGFGMTCQY
RSDFLNIKG------FDVDMKGWGGEDVY--------------LYKKYLQSD--LKVIRV
PDAGIFHTYHPKECSE-----DLTAEQYHMCIGSK----ARSEASHSQLGRLAFKDDINM
TLYLMGDSKHQPPH----------------------------------------------
------------------------------------------------------------
-----------------
>gi|73978718|ref|XP_539923.2|	Canis familiaris
MAGPTTMRLSSLLALLRPALPLILGLSLGCSLSLLRVSWIQGEGEDPCVEAVREPG----
-------VPHNPDS------RTGLDQSD---EDFKPRIVPYYR-DPNKPYKKV-----LR
TRYIQTELGSRE------RLLVAVLTSRATLSTLAVAVNRTVAHHFPRLLYFTG-QRGAR
TPAGMQ-VVSH----GDERPAWLMSETLRHLHTHFGADYDWFFIMQDDT-----YVQAPR
LAALAGHLSINQD--LYLGRAEEFI----------------------GAG-EQARY----
---CHGGFGYLLSRSLLLRLRPHLDGCRGDILSARPDEW---LG-RCLIDSLGIG-CVSQ
HQ--------GQQYRSFELAKNRDPEKE-----GSSAFLSAFAVHPVSEGTLMYKLHK--
----RFSALELERAYGEIEQLQAQIQNLTMLTPEGE-AGLSWPIGLPA---PFTP-----
---HSRFEVLGWDYFTEQHTFSCADG----SPKCPLQGA---NRADVGDAVETALEQLNR
RYQPRLR----------FQKQRLLNGYRRFDPARGMEYTLDLLLE--------AVTQRGH
RRA---LARRVSLLRPLSRVE-----ILP------------------------------M
PYV---T-----E--ATRVQLVLPLLAAEATAALAFLEAFAAGVLEPREH-ALLTLLLVY
GPREGGRGA-PDPFLGVKAAAAELERRYP--GTRLA-WLAVRAE----------------
-------APSQVRLMDVVS-KKHPV------DTLFFLTTVWTRPGPEVLNRCRMNAISGW
QAFFPVHFQEFNPALAPQRSPPGPPGAGADPPSPPGADPSRGAPVGGRFDRQASAEGCFY
NADYLAARARLAGE-LAGQEEEEALEGLE--------------VMDVFLRFSG-LHLFRA
VEPGLVQKFALRDCSP-----RLSEELYHRCRLSN----LEGLGGRAQLAMALFEQEQAN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|156547033|ref|XP_001601123.	Nasonia vitripennis
----MSPVINILFSHCRSNIYLIVGVCVGLSISLLFAPIEINDCQDLEESLPYSISSNEL
---------------------------I---DEYEPKINIEAKPQKAKRVPKV----FVR
PRYYSTELGIRD------KLFIGVLTSPEYLHSRAIALNKTVSHLVDKVRYFISIPEGTK
PNVSLPGIVGF----TDTRSILQPFHVLKYITDNYLEDYDYYFLVKDTS-----YINARK
LTEIVNQISVSQDVHL-------------------------------GIGSGDDAY----
---CSLDGGIILSNSVIKKLKNNLDWCVKTTFSSSDDVN---IG-RCILHSASLP-CTHK
AQ--------EQIYFSTKLNVTFDYQNDFKKLCADEDFQKSITIYPIYDHLMIYNINT--
----HFAEMELLKVEKEIDSLRKQIVKTTSFTPKNQ-QDLSWPIGNQP---GSNA-----
---MNRFDILRWTYFNMTHVFLDDDF----GTVKELNDY---QKEDVNNVVNVTVKRVVD
NYNKQ------------LKFNKLLNGYWKFDSSRGVDYILDLSFA------------TDS
GVE---VNKRIEVCKPLGKVE-----ILP------------------------------V
PYV---T-----E--NSRINMIIAVDAFKKEECMKFLAHYADTCMDRKDK-VTLTVVLLY
NPGYASKGN-EDIFHEIKKRALFLTEKYKKDQLKVT-WLSIRLP--------------TI
SSFIEIEPLLKIAIADLYV-KKFSS------DNLILFADTRMELKSEYLNRVRMNTISQW
QVFSPIPFVQYNPDIIY----------YDASVKHVDFDIIHNH---GRYDDYNYDSVSFY
TKDYMTVRKSIENQ-VPLVRTDKDIASML----QLSQTISIGSIFEMFVVFSN-LNTFRA
VEPALKLKYKEINCIG-----TRNNITLNTCLKQR----NLQLGNRGQLTRLILDYKDHQ
------------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|125983828|ref|XP_001355679.	Drosophila pseudoobscura
------------------------------------------------------------
-------------------------------------------------VKNV-----IR
PRYYSSELGIRE------KLFIGVMTSQEHINSFATAFNRTTAHLVNKIKFFIY-ADSVK
TNYKLKNIVGF----ADTHENRRPFHVIKYIADNYLEEYDYFLLVPDNV-----YVDARK
LSALLYHMSITFD--LYMGGTHIGVPSSEGDGPA-------------GSGSGDRNY----
---CSLEAGILLSSSVIRKMRNNLDRCVRIGITGDHSVN---IG-RCVKYASHVPGCQES
FQ--------GMRQYSYALNTPGRQRRDFSELAKEEAFRNASTVYPVPTPEDFYRLHA--
----YYSKQHLETVQERGYALEQKSYRIANGSISNKILEIRWPLGVPP---PSAP-----
---ETRHDILIWQMLNETHSYLPNGN--VEHAVAPLTRI---EALDFAKVLEIALQYAAL
KHPG-------------LSYHSLHTAYRKFDATRGMDYQLHLNLQ------------KGS
GRRRRLLLKSFEVVKPLGRVE-----VVP------------------------------S
PYV---T-----E--STRIAILVPAFEHQVPDALEFVAQYERLCMQNQDN-TFLLLIFLY
RLDSPSKGD-EDPFKGLKTLALDLSSKYKTDGSRIA-WVSIRLPEQLSEAVR-PEDWLLH
ASMYGPKQLLSLVVADLAL-PKLGL------ESLVLLATPGMSFKADFLNRVRMNTIQGF
QVYAPIGFQMY-PCRWA-----------QFCKECEACDVAQSS---GYFDRHNHDVIAFY
SRDYVQARKLLHPQGLPIIRSDLDIDQLL-EPASQSRPEGVESILDMFVAAQHSVHILRG
VEPNLRFGHDVRNHLG--RGSTLPEQLPEQCGREQ----CIHLASRKQIGDAIIRYEDRS
ILHK--------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|24641671|ref|NP_572853.1|	Drosophila melanogaster
------------------------------------------------------------
-----------------------------------------MSGAKNRQVKNV-----IR
PRYYSSELGIRE------KLFIGVMTSQEHINTFATAFNRTTAHLVNKIKFFIY-ADSVK
TNYKLKNIVGF----TDTRESRRPFHVVKYIADNYLDEYDYFLLVPDTV-----YVDARK
LVKLLYHMSITFD--LYMGGARIGLDPSGGGASADGQSNEPPANEEEAPGASDRNY----
---CSLEAGILLSSSVIRKMRNNLERCVRIGSTSDHSVN---IG-RCVKYASRVAGCQES
FQ--------GMRQFSYALDAPGRRHREFSELAKEEAFRNASTVYPVQTPEDFYRLHA--
----YYSKHHLEKVQERGYALEQKSYRIANGSISNKILEIRWPLGVPP---PSAP-----
---ETRHDILTWQLLNGTHNFLPNGN--AEHAVATLSRI---EAQDFAKVLEIALQYAAL
KHPR-------------LSYHSLHSAYRKFDATRGMDYQLHLNLQ------------EGS
GRSRRLVIKSFEVVKPLGRVE-----VVP------------------------------S
PYV---T-----E--STRIAMLVPAFEHQVPDALLFVEQYERICMQNQDN-TFLLLIFMY
RLESPSKGD-EDPFKALKTLALDLSSKYKTDGSRIA-WVSIRLPEQLSEPVD-PQSWLLH
ASMYGPRQLLSLVVADLAL-PKLGL------ESLVLLATPGMVFKADFLNRVRMNTIQGF
QVYAPIGFQMY-PCRWA-----------HFCRECDTCDVSQSS---GYFDRHNHDVIAFY
SRDYVQARKLLHPQGLPIIRSDLDIDQLLLQPGEETRPPGVESILDMFVAAQHSVHILRG
VEPNLRFGQDVRNHLA--RGGTLPQSVPERCGREQ----CIHLASRKQIGDAIIRYEDKS
ILHK--------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|125814735|ref|XP_690000.2|	Danio rerio
----MLALRTLNQRRLMVYFFYLLIICILFYIFIYLGSYYVYSRDKILPAVPVTTDLSKD
----------------------------------------------------------IR
KRESAADNETQETEDEDDELADKTYQGRVNMHVFEDCCGGSLDQLRNNLLYPLF--PNVR
TSVSRLAVSPQ----GNSYG----LRIFGFLHPAETNEYIFAVASDDNSEFWLSLNKSPK
KLQLLAYVGETGNEWTAPGEYWKFATQISKP----------------VLLVKDRKYFFEV
LLKQNTGMDHLEIAWSLNQGNSTFSVITSEYLSLYKDESSLLMG-----DIEHVPQTKAS
YDRFLEPNPLSLHQREIIREDPRDHIYKYKML--EESFLKDLF--PECDYKPSYVLKE--
----HIGRYQGVYLVQFSSVYPNDYTRQTNDQNDGMCFYRQDPSFLADSEIFYKPKLGEG
PFWHRVYDVNPLNAASKQTTIVAN--------SCRTSGNIVMSQSQALPIVTAFLKALHS
REDTQG-----------YSLLRVVNVVKREDKDLGSRYLVELELV----------DPQGQ
TVL---VSRYIYAQDENSSKPA----LLC------------------------------S
PKAFNWN-----P--SATVHIIVAV-KDQARWIIQFIREMEKIYQATGDK-NFNVIIVDY
NSSD-----------------INIEKRLE--MAKLPSYKLKKMG----------------
------GNFERSGGLQAGIDLVEDE------HSILFLCDLHLYYPVTIINSIRKHCVEGK
MVYAPVVMRLD----------------CGASPRTPN----------GFWEIAGYGLMGIY
KSDMDRIGGMN----TVEFKDKWGGEDWE--------------LLDRVLGNG--LEVERL
HLKNFFHHFHSKRGM-------------------------------------WVNSNSEK
KEK---------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|54400738|ref|NP_001005906.1	Rattus norvegicus
------MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWV----EEPCGPGPPQPGDSEL
PPRGNTNAARRPNSVQPGAERERPGAD----ESWEPRVLPYHPAQPGQATKKA-----VR
TRYISTELGIRQ------KLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTG-ARGRR
TPSGMA-VVAL----GEERPIGHLHLALRHLLEQHGDDFDWFFLVPDAT-----YTEAHG
LDRLTGHLSLASATHLYLGRPQDFI----------------------GGETTPGRY----
---CHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEW---LG-RCILDATGIG-CTGH
HE--------GMHYNYLELS-PGEPVQE-----GDPRFRSALTAHPVHDPVHMYQLHK--
----AFARAELDRTYQEIQELQWEIQNTSRLAADGE-RASTWPVGIPA---PSRP-----
---ASRFEVLRWDYFTEQHTFSCADG----SPRCLLRGA---DQADVADVLGTALEELNR
RYQPALR----------LQKQQLVNGYRRFDPARGMEYTLDLQLE--------ALTPQGG
RWP---LTHRVQLLRPLSRVE-----ILP------------------------------V
PYV---T-----E--ASRVTVLLPLAAAECDLASGFLEAFATAALEPGDA-AALTLLLLY
EPRQAQRAAHADVFAPVKAHVAELERRFP--GARVP-WLSVQTS----------------
-------APSPLRLMDLLS-KKHPL------DTLFLLAGPDTVLTPDFLNRCRMHAISGW
QAFFPMHFQAFHPAVAP-----------PQGPGPPE--LGRDT---GHFDRQAASEACFY
NSDYVAARGRLV---AVSEQEEELLESLD--------------VYELFLRFSS-LHVLRA
VEPALLQRYRAQPCSA-----RLSEDLYHRCRQSV----LEGLGSRTQLAMLLFEQEQGN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|118790332|ref|XP_318249.3|	Anopheles gambiae
------------------------------------------------------------
-------------------------------------------MMAKKVVKNI-----IR
PRYYYSELGIRE------KLFVGVLTTSENVETIATAINRTAAHLVDKIKFFIH-ADNVK
SSFNLKNIVGF----TDTREHLRPFHMLKYLADNYLDEYDFFLLLTDTT-----YVNARM
VRRQLQHLSVTLD--VYIGTNIGYVTDQDEN----------------INESNQNQY----
---CDLNAGIILSSGLIRKVRANLDWCVRNAVSNYHSVN---IG-KCVKYSAKIKTCHQS
WQ--------GVDITSYNIA-GYKIYRDFHLIAEQEAFNKAAMVYPITSMDDFYLLHA--
----YYSRVHLKQNTIVKRLLQNDAMQLSNRTLSNDILEVRWPLGVPK---SNPT-----
---ESRHDVVPWVTLNTTHSFMWQSE----VNVKRLSAI---DEEDIRNVLNKTILHAIR
THPD-------------AEFRGIHTAYKRFDTVRGMDYRLLLNFY--------------D
RKRRTMVQKSFEVIKPISLIE-----IIP------------------------------S
PYV---T-----E--STRVALLLPVFESQILEAEQFMELYEKTCMESQDN-TFLMLIFFY
RAETPSKGD-QDVFLPLKNIALALTEKHKQDGSRVA-WVSIRLP--IDESITFNNSNRYS
SSLNVPQTLMNFVAVDLAL-RKIGL------ESLVIVCTNSASFRPDFLNRVRMNTIQGF
QIFSPIGFMMY-PCEWT-----------GLCKLCENCDVGQSS---GYFDHDNYDVVSFY
SNDYVLAPL------LPIVRNDKDILNFISTISSHYSNPTISNIADLFTQSNNKMHVLRA
IEPNLRFGRSVINSLS--KDHSGKQISEFRCSKQKEKNKCIKVASKKQIGEVFVQYSKQF
GSHEFV------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|91091240|ref|XP_968234.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MNATR
--------------------------------------------------------CCCR
LKIQQRHTDTLQ-----------------------------------EPEVRPKRW----
---EHGEIG------------------RENIWSIAKDIVIIILS-QPNEHHLKVAENLKK
EL--------NEQAESLQQEKPVVYFSH-----KDFPHVGHWTILPLI--PQLYALHKDN
TSWFFFAE---DRTKVNLANLRKALSK----------YDSNKPLWLGH---SLHD-----
---MEATIIHHFAFYDNPNQF-----------KFPNPAS---GIAVSANLLKRLADRLAQ
QNTPQSD----------FGIDNAHE-FALFVWDKGLGEVLTNEPT-------FCITQYKD
CAT---YAQPFQQCGELVETE-----SI--------------------------------
-YFAVKT-----C--AKFHKERVPVVQKTWAKHVATIEFFSDTT---DNS-IPTINLGIP
NTEQGHCAKTLAIFHHIRKKI----------TPQIK-WIVLADD----------------
-------------------------------DTILGVSRIRQLLTC-------YNSTNQV
ALGERYGYNVYDSR--------------------------------GYNYITGGGGIIFS
KPLLKKLTE-------PGFCECPSINTPD----------------DMFLGLCIASLGVSV
THSPLFHQARPVDYPP-----QYLQTQDAVSFHKH------WMIDPVSVYNKWFAEDDKK
VSIIRDEL----------------------------------------------------
------------------------------------------------------------
-----------------
>gi|47210467|emb|CAF94230.1|	Tetraodon nigroviridis
----TKMRFSALVSVLHSVGPVVIGVSLGFTLSLLCVSWTDEACYSPGEEGEGLTLGRDG
PPRGARKPSSVSN-----------GHDTEPEEDFEPRIVPYKQVQPSSPKKVFRQVPSLK
AKYISTELGIRE------RLFVGVLTSKNTISTLGVAVNRTISHHLDNVIFFTG-TRNRK
VPHGML-VVSH----GDERLIWNMFQNVKYIFDHYINEYDWFYFVQDDA-----YTEADQ
LKSLVEHLSLDRE--LYMGSPEEFI-----------------------GGEVEGKY----
---CYGGFGYILSRALLLRLQPFLENCRNDILSARPDEW---LG-RCIIDYTNTN-CVGE
FE--------GLRYHRFELGKNSDPSKE-----QSEQLTGALTVHPVSDPEQMYRLHR--
----FFTELELQKAYSEIVRLQAEIMNVSADAFEGS-WSSQWPVGVNP---PFQP-----
---QSRFEVLKWEYFTEEEIYSCVDG----SPKCELRGI---DRLDVANVIDAAMGELNR
KYKPVLH----------LKKQQLINGYRRFDPTRGMEYTLDLQVE--------AVNQKGH
SRS---ITKRVHLVRPLSKTE-----IIP------------------------------M
PYV---T-----E--ATRVHVILPLTLQERGFASRFLEVFASKALETSEN-AILTFLFIY
DPVEAQQVNQNDIFAGVKSQISAYEHKHP--AAKIP-WISVKTE----------------
-------TPSQIKFMDIIS-KKHPV------DTLFFLANANTEINSEFLNRCRMNSINNW
QVFFPVHFQDYKPEVAY-----------HKQPPPVATHLVKEA---GHFDRLSFGEACFY
NSDYMATRTRNGGR-RAGERGDPGDAG--------------------HLR-----HVREV
LGPARVQGGGAGAAPE--------------VRVPG----VQPTAERGHLPPVHPEQPGGP
GLPLAARHAAL-------------------------------------------------
------------------------------------------------------------
-----------------
>gi|119888465|ref|XP_590807.3|	Bos taurus
------MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWV----EEPCGPGPPQPGDSEL
PPRGNTNAARRPNSVQPGAERERPGAGAGAGENWEPRVLPYHPAQPGQAAKKA-----VR
TRYISTELGIRQ------KLLVAVLTSQATLPTLGVAVNRTLGHRLERVVFLTG-SRGRR
APPGMA-VVTL----GEERPIGHLHLALRHLLEQHGDDFDWFFLVPDAT-----YTEAHG
LARLVGRLSLAAAAHLYLGRPQDFI----------------------GGEPAPGRY----
---CHGGFGVLLSRTLLQQLRPHLEACRNDIVSARPDEW---LG-RCILDATGVS-CTGD
HE--------GVHYSYLELS-PGEPVQE-----GDPRFRSALTAHPVHDPVHMYQLHK--
----AFARAELERTYQEIQELQWEIQNTSRLAADGE-RAAAWPVGIPA---PSRP-----
---ASRFEVLRWDYFTEQHAFSCADG----SPRCPLRGA---DRADVADVLGAALEELNR
RYHPALR----------LQKQQLVNGYRRFDPARGMEYTLDLQLE--------ALTPQGG
RRP---LTRRVQLLRPLSRVE-----ILP------------------------------V
PYV---T-----E--ASRLTVLLPLAAAERDLAPAFLEAFATAALEPGDAAAALTLLLLY
EPRQAQRAAHADVFAPVKAHVAELERRFP--GARVP-WLSVQTA----------------
-------APSPLRLMDLLS-KKHPL------DTLFLLAGPDTVLTPDFLNRCRMHAISGW
QAFFPMHFQAFHPAVAP-----------PQGPGPPE--LGRDT---GRFDRQAATETCFY
NSDYVAARARLA---ASSDQEEELMESLD--------------VYELFLRFSS-LHVLRA
VEPALLQHYRAQTCSA-----RLSEDLYHRCRQSA----LESLGSRTQLAMLLFEQEQGN
ST----------------------------------------------------------
------------------------------------------------------------
-----------------
>gi|47216537|emb|CAG04715.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------MPRRGLLPHGRVRWLFLGLFLLLV------
------------------------LLLFTYLLECT---------------------PPAD
ISLVLPGLA--------------------------------------GENNGKEYY----
----------------------------QALLQEQEERH---LN-RATSLKRQIAQLKQE
LQ--------EMSDKLKLLQ-------------------------DKKEPPAVQGLAE--
--------TKDQEPGDLLDYLHSQI------------DKAEVNTGARF------------
---PSEYALIPFESFTSSKVYQLEMGLTRHPEEKPVRRD---RRDELVEVVEAALDIINN
PDEEDGVEEDVPMQRQTYTEVHFTEGLYRTERDKGTLYELFFAKE---------------
DSS---SFRHVTLFRPFGPLM-----KVR------------------------------S
TSV--ET-----S--GAIINIIVPL-SGRVEAFSQFLHNFREVCILHDRR-VHLTVVYFG
QEGLQEVKS-------------SLEKVSR--EESFSNYTLIPVD----------------
------EEFSRGRGLDIGA-HAWKRG-----DVLMFFCDVDIHFSLEFLNTCRLHAAPNK
RVFYPVVFSLYNPAIVYGNL-------ELAPPIELQLIHKKDA---GFWRDFGFGMTCQY
RSDFLNIAS------FTVARE----------------------------------TVRGR
ADAGAVPHVHPVQGDE--RGLPLPPGHAGVPRGDRGSPTQAGLQDSEQAGGLSQPPPPPP
HNTVLIIDN---------------------------------------------------
------------------------------------------------------------
-----------------
