>gi|109498240|ref|XP_222934.4|	Rattus norvegicus
--------------------------------------------------MEIRQHEWLS
ASPHE---GFEQMRLKSRPKEPSPSLTRVGANFYSSV-KQQDYSASVWLRRKDKLEHSQQ
KCI-VIFALVCCFAVLVALIF------------------SAVDIMGEDEDGLSEKN----
-----CQ-----NKCRIALVENIPEGLNYS--EDAP----FHLPLFQGWMNLLNMAKKSV
DIVSSHW-----DLNHTHPSAC------------------------QGQRLFEKLLQL-T
S--QNIEVKLVSDVT-ADSKV---LEALKLKG-AEVTYMNMTAYN---KGRLQSSFWIVD
KQHVYIGSAGLDWRSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFK-SRVPQTWSKR
LYGVYDNEKKLQLQLNETKSQ-AFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVT
DYLPISSTS-TKRTYW-PDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAIC
TEIANC------------------SLKVKFFDLERENACATKEQKNQTFPKLNRNKYMVT
DGAA-------------------YIGNF-DWVGNDFTQNA--GTGLVINQ----ADVRDN
RSIIKQLKDVFERDWY-----------SPYAKSIQPTKQPNCSNLSKLKTPSNQPAIYNT
TGREPLSV----------------------------------------------------
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>gi|149749451|ref|XP_001493049.	Equus caballus
------------------------------------------------------------
-------------------------------------------------------MKSQQ
KCI-VIFALVCCFAILVALIF------------------SAVDIMGEDEDGLSEKN----
-----CQ-----NKCRIALVENIPEGLNYS--ENAP----FHLSLFQGWMNLLNMATKSV
DIVSSHW-----DLNHSHPSAC------------------------QGQRLFEKLLQL-T
S--QDIEIKLVSDVT-ADSKV---LEALKLKG-AEVTYMNMTAYN---KGRLQSSFWIVD
KQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFK-NRVPLTWSKR
LYGVYDNEKKLQLQLNETKSQ-AFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVM
DYLPISSTS-TKRTYW-PDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAIC
TEIANC------------------SLKVKFFDLERENACATKEQKNHSFPKLNRNKYMVT
DGAA-------------------YIGNF-DWVGNDFTQNA--GTGLVINQ----ADVRNN
ASIIKQLKDVFERDWY-----------SPYARTFQPTKQPDCSSLFKLRAPSNKTATSNA
SGKDPASV----------------------------------------------------
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>gi|73961433|ref|XP_547493.2|	Canis familiaris
--------------------------------------------------MEKNRELFLY
GQEQDRKVNLPTYRKQLSDKWGHPSQTLFAMNLAVRF-ATDVLFLCMLFPSCAPFLMSQQ
KCI-VIFALVCCFAILVALIF------------------SAVDIMGEDEDGLSEKN----
-----CQ-----NKCRIALVENIPEGLNYS--ENAP----FHLSLFQGWMNLLNMAKKSV
DIVSSHW-----DLNHSHPSAC------------------------QGQRLFEKLLQL-T
S--QNIEIKLVSDVT-ADSKV---LEALRSKG-AEVTYMNMTAYN---KGRLQSSFWIVD
KQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFK-NRVPQTWSKR
LYGVYDNEKKLQLQLNETKSQ-AFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVM
DYLPISSTS-TKRTYW-PDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAIC
TEIANC------------------SLKVKFFDLERENVCATKEQKDHSFPKLNRNKYMVT
DGAA-------------------YIGNF-DWVGNDFTQNA--GTGLVINQ----ADVRNN
RSIIKQLKDVFERDWY-----------SPYARTLQPTKQPNCSSLFRLKPPNNKTATYSA
SAKDPASV----------------------------------------------------
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>gi|94733348|emb|CAK05474.1|	Danio rerio
---------------------------------------------------MKSDIPYEK
--------MVDVELSRGEGHHGSQ-----------------------------KYYRCLI
VLT-CITTVLLILLSLQTLLV------------------PMAKSSSTKSSVQQERV----
LIRETCT-----DPCRIVLVESIPEGMVFN--SS------VHQSIYDAWLNLISATQSSL
DIASFYWTLTNSDTHTQEPTAN------------------------QGQQILKKLGQL-S
S--K-AYVRIAVDKP-ADKKPMEDINFLSSYG-ADVRMVNMRELT---TGVLHTKFWIVD
KKHIYIGSANMDWRSLTQVKELGAVVYDCSCLAEDLGKIFEAYWYLNQT-KTVPAHWPNK
YSTLYNKDTPMQLSLNGTSAS-VYLSSSPPSLCAEGRTPDLQSILDVIANAQQFVYIAVM
NYLPTMEFS-RSKRYW-MDIDTELRRVAYERRIRVRLLISCWNSTKPIMFPFLRSLASLQ
D-TNQL------------------DIQV--------------------------------
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>gi|118151178|ref|NP_001071509.	Bos taurus
---------------------------------------------------MKPKLMYQE
LKVPAEEPASELPMNEIEAWKAAE-----------------------------KKARWVL
LVL-ILAVVGFGALMTQLFLW------------------EYGDLH------LFGPN----
QRPAPCY-----DPCEAVLVESIPEGLDFP--NAST----SNPSTSQAWLGLLAGAHSSL
DIASFYWTLTNNDTHTQEASAQ------------------------QGEEVLRQLQTL-A
P--RGVKVRIAVSKP-NGPQPQADLQALLQSG-AQVRMVDMQKLT---HGVLHTKFWVVD
QTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRP
YDTRYNQETPMEICLNGTPAL-AYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYIAVM
NYLPIMEFS-HPRRFW-PAIDDGLRRAAYERGVKVRLLISCWGHSDPSMRAFLLSLAALR
DNHTHS------------------DIQVKLFVV----PA-DDAQARIPYARVNHNKYMVT
ERAT-------------------YIGTS-NWSGSYFTETA--GTSLLVTQ-------NGR
GGLRSQLEAVFLRDWD-----------SPYSHDLDAAADSVGNACRLL------------
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>gi|157018925|gb|EAA06428.4|	Anopheles gambiae
------------------------------------------------------------
-----------------------------------------------------GWSSCIP
ITI-ILVLIVLVVLLPLMDHS------------------ERAGETGEPARAGVGRL----
GHPIACP-----ETCSLELVESIPEGMAYP--DGSP----TFRTTFQAWSALLELAQATV
EIGSFYWTLKGADVY-NHSSAR------------------------EGETIFRKLYEAGT
V--RKLQVKIAQSAP-TSASPNLDTDLLAKQGAALVRSVDFPRLVG--GGVLHTKVWLID
RNHFYLGSANMDWRSLTQVKELGVLGTNCSCLVQDLAKIFDVYWDMGAPDARIPPKWPKA
YAASFNYSAPAHVEFNGRNAMDAYFSSSPPMMSPAWRTDDLFAILDVISKANRFVHISVM
DYFPLTLYT-RITQYW-PYIDDALRKAAIERKVSLRLLISLWDHSRPSEEYFLHSLEALS
NALTGV------------------DIQIRRFIV----PA-SDDQKKIPFGRVNHNKYMVT
DNTA-------------------YIGTS-NWSGDYFIDTA--GIGLVI------SSFDTN
GTIIQELQSVFERDWN-----------SKYAVRLS-------------------------
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>gi|126290318|ref|XP_001372332.	Monodelphis domestica
--------------------------------------------------MAAGAQAGQD
MVEGRTRIFMYFLRPAILPPVLNLEVEKEEDLLYRPW-GNEKTFTEEGQSNGGELEEKEV
EEE-AWSSVDACNGQLVNVSSKNAHSALDGSARGGR--GPIIPFMLDTVALVMVVGSGKN
RHEAPQS-----NGGTFVLVESIPEDLPYL--PARP----AAQPLIQSWMELLDSAQDSV
HVASFYWSLTGSDIGVNDSSSQ------------------------PGEELLEKLETL-L
A--RNVSLTIATSDP-TLALNSTDLEVLMGKG-AQVRKIPMKHLT---QGVLHSKFWIVD
MKHVYLGSANMDWRSLTQVKELGIVIYNCSSLAHDLEKTFQTYWILGAPGATIPKHWPQN
YSTNINWHQPLQGTLDGMVTT-AYFSASPPVLCPKGRTRDLGALLSLIRDAKDFLYASVM
EYFPTSRFQ-HPFKYW-PVIDNALREAAFNRHVPIRLLISCGKNSDPSMFPYLRSLQALT
NPQANV------------------TIDVKIFII----PV--GNHSNIPFSRVNHSKYAVT
EKKA-------------------YVGTS-NWSEDYFTNTA--GVGVIVNQSSS-DPQHPA
PTIQDNLRGIFERDWQ-----------SPYAISLEKLPGQQDCVWHA-------------
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>gi|47221032|emb|CAG12726.1|	Tetraodon nigroviridis
--------------------------------------------------MLRRRQEHAR
--------KAQFVRHRHKPDTGEEKPSTPELVIFNLI-FILNFTCCSCVL---QYSRCVI
VLI-ALATLLLVCMASYHFLS------------------PKVPFLHPSLSSSLGQP----
---QTCS-----DPCNIVLVESIPEGLQFN--SST-----AHPSIFQAWLALMNEARSSV
DIASFYWTLTNSDTGTQEPTAE------------------------QGETVLKRLAQL-S
G--K-LSVRIAVNTP-VGRKN-DDLRLLNNSG-ADIRTVNMRDLT---SGVLHTKFWIVD
KKHVYIGSANMDWRSLTQVKELGTAIYNCSCLAADLGKIFEAYWFLGAS-QSVPSPWPDR
FTTRYNKDTPLQLPLNNTPSR-VYLSSSPPSLCAAGRTQDLQSILSVMEDARSFIYIAVM
NYLPTMEFS-HPKRYW-ADIDTQLRRVAYEKRVKVRLLISCWASTQPLMFPFLKSLASVY
DLKSKL------------------DIQVRLFVV----PA-SPEQKEIPFARVNHNKYMVT
DRVA-------------------YIGTS-NWSGDYFVNTA--GSALVVNQS---SAPSSE
TTVQSQLRAVFERDWD-----------SAY------------------------------
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>gi|116007352|ref|NP_001036372.	Drosophila melanogaster
------------------------------------------------------------
--------MSERRVVHEIPGEYQPVPRAPEEPTPLTT-SCCRRPNCGLGLQDERNICSCK
HGY-IIPVLILFVLVMIVLLL------------------PWETYHRNENGNSPVPV----
----EKP-----LPCQLELVESLPLGLNYSQWQSHP----QLSSTFDAWQLLLGRAKASL
DIVSPHWTLRGLDVNDSSTG--------------------------PGDQLFQQLLSNGD
AGRPKLRVRIVVNRS-HDSLWHADARILANYGAADVVGINF----------LHSKLWLVD
GEHFYLGTASMDWRSLTQRKELGVLARNCPHLALDLGKIFKAYWYLGS--NEVPKSWPWI
YHTHINQRRPLLLNINKKHTMRAYLSTSPPELIATGRTRELDAILEAIDKATDVIYLSLM
EYSPRLRRS-NKLEYW-PVIDNALRRAALERGVAIKVLISWWKYSDPSEDHFLRSLQALD
KITEGV------------------DIQMRRFVV----PT-TNELERISGVKISMAN-KPT
RDVIGIIFKNFWKSLRPRQFRGDYIGED-YFGNKYYEIPANPSIGKRKPSRW--FEPADK
EAFDQELTAEWE-AWLRGRREE-----PPTREELVKNLQIMDMKKRNAAELEATYAKGKD
DKALPKQVDGPTIGTFPKYKEYEFIPGKEPPEK---------------------------
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>gi|109019819|ref|XP_001092989.	Macaca mulatta
--------------------------------------------------MEIRQHEWLS
ASPHE---GFEQMRLKSRPKEPSPSLTRVGANFYSSV-KQQDYSASVWLRRKDKLEHSQQ
KCI-VIFALVCCFAILVALIF------------------SAVDIMGEDEDGLSEKN----
-----CQ-----NKCRIALVENIPEGLNYS--ENAP----FHLSLFQGWMNLLNMAKKSV
DIVSSHW-----DLNHTHPSAC------------------------QGQRLFEKLLQL-T
S--QNIEIKLVSDVT-ADSKV---LEALKLKG-AEVTYMNMTAYN---KGRLQSSFWIVD
KQHVYIGSAGLEWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFK-SRVPQTWSKR
LYGVYDNEKKLQLQLNETKSQ-AFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVM
DYLPISSTS-TKRTYW-PDLDAKIREALVLRSVRVRLLISFWKETDPLTFNFISSLKAIC
TEIANC------------------SLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVT
DGAA-------------------YIGNF-DWVGNDFTQNA--GTGLVINQ----ADVRNN
RSIIKQLKDVFERDWY-----------SPYAKTLQPTKQPNCSSLFKLKPPSNKTATDDA
GGKDPWNV----------------------------------------------------
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>gi|58332376|ref|NP_001011023.1	Xenopus tropicalis
---------------------------------------------------MNPKVEYKQ
IQSHD---EAENQVLQHECHQAKAR----------------------------KYYRCAV
VIA-IIITLLFCVLASQLLLF------------------PLFSITSQTTTEIVLNK----
--DIQCD-----DQCRFVLVESIPEGLVYD--ANAT----INPSIFQSWLNILTSAKSSV
DIASFYWTLTNEDTQTQEPSAH------------------------QGELILQELLNL-K
Q--RGVSVRVAVNPP-DSPLRAKDISALKDSG-ADVRVVDLPKLT---DGVLHTKFWVVD
SEHFYIGSANMDWRSLTQVKELGATIYNCSCLAEDLKKIFEAYWILGLPNATLPSPWPVN
YSTPYNKDTPMQVMLNSTASQ-VYISSSPPPLSATGRTDDLQSIINIIDDAKKFVYISVM
DYSPTEEFS-HPRRYW-PYIDNHLRKAVYERNVNVRLLISCWQNSRPSMFTFLRSLAALH
SNKSHY------------------NIEVKIFVV----PA-TEVQKKIPYARVNHNKYMVT
DRVA-------------------YIGTS-NWSGDYFIHTA--GSALIVNQT---QSVGTS
DTIQMQLQAVFERDWN-----------SNYSRTFNTLSSWKEKCIF--------------
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>gi|115803243|ref|XP_793309.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
--------MGEYKAIQNDDREEAVIKD--------------------------GAVKRGL
SCS-LVAVFFIAILTSLIFLV------------------IWV-IANPPVVNPAPVP----
-----CD-----DPCVVILAESMPLNLTFP--DGSP----RFQSTYAIWKELLATAKETI
DISSYYWTLRGKDIF-NDTSDF------------------------EGEEIFKELMAAGT
T--RNISIRIVENKP-SHYIADLDTKELAAKGAAQVQSLDFNELMG--GGILHTKFWVVD
KKHLYLGSANMDYRALTQVKEIGVGIFNCSCLAQDLDKLFEVYWYLGNQ-TTVPPKWPEE
FATAYNLETPMQLKLNGTNAT-AFIGSSPPAFCPSGRTSDIDGLLNVVESAQKFVYIAVM
DYIPEKEFA-NPMEYW-NVIDAKLREVAFNHHVN--------------------------
----------------------------KLFCV----PAYTPVEHEMPYARVNHNKYMVT
DNAA-------------------YIGTS-NWSGTYFTLTG--GASLVVNQTLA-QMETNA
TTLQHQLAQLFERDWN-----------SIHATPVL-------------------------
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>gi|83627695|ref|NP_795890.2|	Mus musculus
--------------------------------------------------MEIRQHEWLS
ASPHE---GFEQMRLKSRPKEPSPSLTRVGANFYSSV-KQQDYSASVWLRRKDKLEHSQQ
KCI-VIFALVCCFAVLVALIF------------------SAVDIMGEDEDGLSEKN----
-----CQ-----NKCRIALVENIPEGLNYS--EDAP----FHLPLFQGWMNLLNMAKKSV
DIVSSHW-----DLNHTHPAAC------------------------QGQRLFEKLLQL-T
S--QNIEVKLVSDVT-ADSKV---LEALKLKG-AEVTYMNMTAYN---KGRLQSSFWIVD
KQHVYIGSAGLDWRSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFK-SRVPQTWSKR
LYGVYDNEKKLQLQLNETKSQ-AFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVT
DYLPISSTS-SKRTYW-PDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAIC
TEIANC------------------SLKVKFFDLERENACATKEQKNQTFPKLNRNKYMVT
DGAA-------------------YIGNF-DWVGNDFTQNA--GTGLVINQ----ADVRDN
RSIIKQLKDVFERDWY-----------SPYAKSIQPTKQPNCSSLSKLKSPSKQPAMANA
TGREPLSV----------------------------------------------------
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>gi|94681038|ref|NP_620145.2|	Homo sapiens
----------------------------------------------------MLKPLWKA
AVAP----TWPCSMPPRRPWD--------------------------------REAGTLQ
VLG-ALAVLWLGSVALICLLWQVPRPP------------TWGQVQPKDVPRSWEHGSSPA
WEPLEAEARQQRDSCQLVLVESIPQDLPSA--AGSP----SAQPLGQAWLQLLDTAQESV
HVASYYWSLTGPDIGVNDSSSQ------------------------LGEALLQKLQQL-L
G--RNISLAVATSSP-TLARTSTDLQVLAARG-AHVRQVPMGRLT---RGVLHSKFWVVD
GRHIYMGSANMDWRSLTQVKELGAVIYNCSHLAQDLEKTFQTYWVLGVPKAVLPKTWPQN
FSSHFNRFQPFHGLFDGVPTT-AYFSASPPALCPQGRTRDLEALLAVMGSAQEFIYASVM
EYFPTTRFS-HPPRYW-PVLDNALRAAAFGKGVRVRLLVGCGLNTDPTMFPYLRSLQALS
NPAANV------------------SVDVKVFIV----PV--GNHSNIPFSRVNHSKFMVT
EKAA-------------------YIGTS-NWSEDYFSSTA--GVGLVVTQSP--GAQPAG
ATVQEQLRQLFERDWS-----------SRYAVGLDGQAPGQDCVWQG-------------
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>gi|75075947|sp|Q4R583|PLD3_MAC	Macaca fascicularis
---------------------------------------------------MKPKLMYQE
LKVPAEEPANELPMNEIEAWKAAE-----------------------------KKARWVL
LVL-ILAVVGFGALMTQLFLW------------------EYGDLH------LFGPN----
QRPAPCY-----DPCEAVLVESIPEGLDFP--NAST----GNPSTSQAWLGLLAGAHSSL
DIASFYWTLTNNDTHTQEPSAQ------------------------QGEEVLRQLQTL-A
P--KGVNVRIAVSKP-NGPQPQTDLQALLQSG-AQVRMVDMQKLT---HGVLHTKFWVVD
QTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRF
YDTRYNQETPMEICLNGTPAL-AYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYIAVM
NYLPTLEFS-HPHRFW-PAIDDGLRRAAYERGVKVRLLVSCWRHSESSMRAFLLSLAALR
DNHTHS------------------DIQVKLFVV----PA-DEAQARIPYARVNHNKYMVT
ERAT-------------------YIGTS-NWSGNYFTETA--GTSLLVMQ-------NGR
GSLRSQLEAIFLRDWD-----------SPYSHDLDASADSVGNACRLL------------
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>gi|7110641|ref|NP_036400.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
--------------MTQLFLW------------------EYGDLH------LFGPN----
QRPAPCY-----DPCEAVLVESIPEGLDFP--NAST----GNPSTSQAWLGLLAGAHSSL
DIASFYWTLTNNDTHTQEPSAQ------------------------QGEEVLRQLQTL-A
P--KGVNVRIAVSKP-SGPQPQADLQALLQSG-AQVRMVDMQKLT---HGVLHTKFWVVD
QTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRF
YDTRYNQETPMEICLNGTPAL-AYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYVAVM
NYLPTLEFS-HPHRFW-PAIDDGLRRATYERGVKVRLLISCWGHSEPSMRAFLLSLAALR
DNHTHS------------------DIQVKLFVV----PA-DEAQARIPYARVNHNKYMVT
ERAT-------------------YIGTS-NWSGNYFTETA--GTSLLVTQ-------NGR
GGLRSQLEAIFLRDWD-----------SPYIHDLDTSADSVGNACRLL------------
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>gi|125987463|ref|XP_001357494.	Drosophila pseudoobscura
------------------------------------------------------------
--------MSERRGVQDIPVDYQPVATQAD-HIPSTS-SCCRRPNCNIVARDEREVCCCG
HGY-IIPVFILFVLVLIVLLL------------------PWETFHRNEGADASTPG----
--PVAAA-----FPCQLQLVESLPTGLNYSG-SNHPQLMVMTLSTFEAWQLLLGKAKTSV
DIAAPYWTLRGVGVNDSSSTQH-------------------------GDQLFQRLLSNGD
AGRPKLRIRIALNRS-QESIWHADARIFSNYGAADVVAVE----------RLRGNFWIVD
GQHFYLGSANMDWRSLSQRKEMGVLGQNCPHLTRDLGKIFKAYWYLGS--NDMPSYWPWI
YHTNINQRRPLLLNVNMNYTMHAYISSSPPPLAASGRAYELDAVLNAIDKATELVCIALV
DYYPLLRHE-SQVEYW-PLIDNALRKAAVERGVVIKLLISWWKYSDPSEDHFLRSLQALS
QLREEV------------------DIEIRRFVV----PT-TEAHEKIAHGRVSHNSYMVT
EDVV-------------------YIGTS-SWSGEQFTYSA--GVGLVLH-----DMVYNN
NSLRTDLLAVFHRDWF-----------SPFSLPLKHNFRI--------------------
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