>gi|83649701|ref|NP_001032871.1	Rattus norvegicus
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQ--------------------------------------
---------------------------------------SPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTPSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-P-----------------EDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSSTSLQNSSSHTTSAKGPGS
GFLH-------PAA-PANANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFGFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPIADNNSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNT
AT---TDSVSWDSPGSWTDPAIITGIPASSGNTLDS---IQDDNP-PHWLK--SLQALTE
VD-GP--SAA-------SPQPHHSAP-----FSTQIPLHR--------------ASWNP-
-Y--PPPSNPSS-FHSPPPGF-----------------------QTAFRPPSKTPTD---
---LLQSSTLDRH-------------------------
>gi|24741192|emb|CAD56154.1|	Kluyveromyces lactis
---------------MNATATENPHVHQNQHEIQKALSNYDTSFLSDDEEDLC-------
--------------PLCIEPLDVMD---------------------------------KH
FKPCPCGYQICQFCYNNIRQNPE---LNGRC------------PACRRKYDDE--SVEYI
VLSPEELK---MERSKQARKERDRKQRERERRENDTHN---RKQLAGMRVIQKNLVY--V
IGLNPPYPYEE---------LPSILRSDKYFG--------QYGKINKIVINKKTGHEHHS
VSNSSSHINSGYGIYVTFSRKDDAAKCIQAIDGIYIDG----------HQVKAAY-GTTK
YCSSYLRGQPCPNP--NCMF------LHEPGEEADAFNNARKEHA---------------
--------------------HHSHA----------PP-----------------------
-TLAKPST----------------------------------------------------
---------------------------------------SASSTPKLAHASLRTDDFTVP
-----------------AAATSSSKQTA---PVLT-------------------------
----------------PAPVPSG-SNPWGISQ------APTPVSTIFNKTS----TSTTF
PTLSSS-------LGETLN-----------------------------------------
------------------------------SPGPGTPTTTGSAPTANSSSNVSSKKKGEK
TYED-------PYDPMATCVKFLDQTFKFLSDIPERSYTFNSNL----LDDETYQS----
---------------YPSLFSFEKIGCSEQSEG----VLGAKLCDLLTIKPV----DHMS
SL----LPFIQNKAT---------------------------------------------
------------------------PTMLPPGIAVQQ----------PQLVQQ-QKQQLQQ
QQ---------------LQQQQQQLS-----LQMQLQAQQ--------------------
-G--MAQQGMAQQVMSQPQS----------------------------------NSSDLL
NQLIHGKKQTAAV-------------------------
>gi|110763985|ref|XP_394121.3|	Apis mellifera
-------------------MTDSTFAAEMDYFWLVEATEHDDNIDYLNLEDIC-------
--------------PQTSQESTSSG-------------------------------SGSG
SGSGSGSHSAMNSVQSDVTVAQ-----NQGM------------EMAQNQMTQS--QAIGM
EMAQNQMTQNQMTQGQMMGMEMAQNQMTQSQMMEMAQGQMAQGQMMGMEMAQNQMTQSQM
MGMAQNQAMGQSESVESSSLLEMLLKRDKPMENGLSEEDKPSAMVQPVMRNGIIEQQGP-
----LCQESPQPSTSSSVSSSNDGSLVNVERQRQVVNQ----------RRVPVTQ--SIN
YSNGYVQNQVYPIR--QPLI------LNSCMQQATATTFQPQPSCS--------------
--------------------HANLNGNL--NVRKQNGI----------------------
-RSNNLRNEQQQQQQQLMRQQQQLQ-----------------------------------
---------------------------------------QQQLQQQ-QRLHHQQQLHHQQ
-----------------MLLQQQQQLQQ---QQQLQQQQQLHHQQMLLQQQQQLHQQQLL
QQQQQQF-HQQQQLHHQQMLQQQQQQQHQQLQQEY---GQQQQRQAEEQRRSQLQQQPQL
YLRQQENQMQQLQQPHTSR-Q-----------------QIQSQTQP--------------
----------------QTLAQSQPQIQSQSQPQTQQQQPQQSQQMNYSWLKPSTSKGETS
---------------NNNGQKRTRQTYTRYQT-LELEKEFHFNR----YLTRNRRL----
------EIARALHLTER-QVKIWFQNRRMKAKK-------------FNKDAE-----NGS
DKGT-GRPRRNQSFT------------------------NRVTATATRATVTTATVTTAT
AT----------------------ATVTSNGAASTAAAYHQTATAMPSCMQ--QQPPQQQ
HQ-QP------------QQHQHHQAVQNGYVYQQQPQQHQH-------------AAFNG-
-YNGYSDQRNNHGGNNQPPL----------------------------------------
--------------------------------------
>gi|149747461|ref|XP_001500144.	Equus caballus
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQ--------------------------------------
---------------------------------------SPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVLPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTSSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-P-----------------EDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSPTSLQNSSSHTTTTKGPGS
GFLH-------PAA-PANANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFNFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPIA--------------------------------------------------
------------------------GIPASSGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-GP--SAA-------PSQTHHSAP-----FSTQIPLHR--------------AGWNP-
-Y--PPPSNPSS-FHSPPPGF-----------------------QTAFRPPSKTPTD---
---LLQSSTLDRH-------------------------
>gi|6320912|ref|NP_010991.1|	Saccharomyces cerevisiae
MMNPHVQENLQAIHNALSNFDTSF-------------LSEDEEDY-------C-------
--------------PLCIEPMDITD---------------------------------KN
FFPCPCGYQICQFCYNNIRQNPE---LNGRC------------PACRRKYDDE--NVRYV
TLSPEELK---MERAKLARKEKERKHREKERKENEYTN---RKHLSGTRVIQKNLVY--V
VGINPPVPYEE---------VAPTLKSEKYFG--------QYGKINKIVVNRKTPHSNNT
TSEHYHHHSPGYGVYITFGSKDDAARCIAQVDGTYMDG----------RLIKAAY-GTTK
YCSSYLRGLPCPNP--NCMF------LHEPGEEADSFNKRELHN----------------
--------------------KQQAQQQSGGTAFTRSG-----------------------
-IHNNISTSTAGSNTNLLSENF--------------------------------------
---------------------------------------TGTPSPA----AMRAQLHHDS
-----------------HTNAGT--------PVLT-------------------------
----------------PAPVPAG-SNPWGVTQ------SATPVTSINLSKNSSSINLPTL
--------------------------------------NDSLGH----------------
----------------HTTPTTENTITSTTTTTNTNATSHSHGSKKKQSLAAEEYKDPYD
A--------------LGNAVDFLDARLHSLSNYQKRPISIKSNI----IDEETYKK----
------YPSLFSWDKIE-------ASKKSDNTL------ANKLVEILAIKPI-----DYT
ASV------------------------------------------------V--------
------------------------QFLQSVNVGVNDNITITDNTKTPTQPI--RLQTVSQ
QI-QP------------PLNVSTPPP--------------------------------G-
-IFGPQHKVPIQ--------------------------------QQQMGDTSSRNSSDLL
NQLINGRKIIAGN-------------------------
>gi|71896211|ref|NP_001025571.1	Xenopus tropicalis
-------------------MSRSP-------------VVKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGTVDKNKNKVTALQRYDVPNSNNKDAWPSLQNSNRSANGLGLEHRKSPPILD
NGLDPDHMTPDGPDSDFGLFWESAEHNVAKFGRVIEDDTSSVDKSS-ESLSIGNGDNLQQ
-----------------ILTSDTPSPP----PGLSKPNPSVPISSANHSARSPF--EDAM
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTSSEWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-Q-----------------EDDLGFDPF-------------
----------------DITRKALADL-IEKELSVQDQPALSPTSLQNPPPHP-AAKGPGS
GFLH-------PTT-AANANSIA-STFSVLPQ-RFPPF-QHRAV----YNSFSFPG----
------QAARYPWMAFP-RNNIMHLNHTANPTS------NSNFLD-LSHPPQ-----HNT
GLG--GITVA--------------------------------------------------
------------------------GIPSSTGNGLES---LQDDNP-PHWLK--SLQALTE
MD-GP--SSSI------PPHHPHNNL-----FSAQIPLHR--------------GNWSP-
-Y--PPPSNPAS-FHSPPPGF-----------------------QTAFRPPTKTPTD---
---LLQSSALDRH-------------------------
>gi|149411765|ref|XP_001512368.	Ornithorhynchus anatinus
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGTVDKNKNKVTPLQ--------------------------------------
---------------------------------------SPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKPNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTSSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-Q-----------------EDDLGFDPF-------------
----------------DITRKALADL-IEKELSVQEQPSLSPTSLQNAPSHTTTAKGSGS
GFLH-------PAAAPTNANSLGGSTFPVLPQ-RFPPFPQHRAV----YNSFSFPG----
------QGARYPWMAFP-RNSLMHLNHTANPTS------NSNFLD-LNLPPQ-----HST
GLG--GIPIAEQFTG---------------------------------------------
------------------------G--STAGSGLPTSALLISGSPLPHFLSRGSLGCILA
V-----------------------LK-----FKRHSTLGN--------------ESWKR-
-L--CPDHTHLT-FVINPANC-----------------GKLSVARMVFIWRVLVI-----
--------------------------------------
>gi|109068332|ref|XP_001105570.	Macaca mulatta
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQRYD-----------------------------------
---------------------------------------TPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTSSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-P-----------------EDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSPTSLQNSSSHTTTAKGPGS
GFLH-------PAA-ATNANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFSFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPVADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNT
AT---TDSLSWDSPGSWTDPAIITGIPASSGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-GP--SAA-------PSQTHHSAP-----FSTQIPLHR--------------ASWNP-
-Y--PPPSNPSS-FHSPPPQIYYRVQHWTAIRQRGATIRKCRICPTLFSPSQPTTHSSLL
ISYVLKNPVPDQFFFSLPPDAMRSQGHYHLFINCKSFC
>gi|61353791|gb|AAX44045.1|	Macrobrachium rosenbergii
-------------------MDDDA-------------DEKDDVKR-------K-------
--------------SRNLSEKKRRD-----------------------------------
--------------QFNLLINE----LSSMV------------ASNNRKMDKS--TVLKA
TIAFLKNQ-------KEISVRTQSNEIREDWKPSFLSN---EEFTHLMLEALDGFIM--T
VSCSGRVLYTSESITPLIGHLPSDLAGTPLYDLMLEE---ERGEMRRFLSNPALAPNPS-
--TCFDNTKEKYTIAVHLRRGTINSSDATNYERVHLMGYF-------ERYSGPSEDGVLD
FSCSEAEDSVSVSSCSRSMF----------GGNAGGGVTGSSNAG---------------
--------------------SGLCQSSLVQTNPSQEPT----------------------
-KLVFVAIGRLERPQLVRE-----------------------------------------
---------------------------------------MMIIEPSKTEFTSRHSLEWKF
-----------------LFLDHRA-------PTIIGYLPFEVLGTSGYDYYHVEDLDKVA
SCHEQLMKTGKGTSCYYRFLTKGQQWIWLQTQY-----YITYHQWNSKPE----FIVCTN
TVVSYSDVKAELVK----------------------------------------------
----------------EQMPNGLSELEINQSESSMGLSGAGPSGTNSMSGQTGVGVGVSV
SV---------SGVQEHSQSQLSEEDTSLQPA-RTPQPGPSHLLLQHQHQEHNIPQ----
--------THLPLTQNQ-QQHIQHLQQQQQQQQ------QQQQQQQQQQQQQ-----QQQ
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
QQ----------------------QQQQQQQQQQQQQQQQQEQQQQQHQQQ--QQQQQQQ
QQ-QQ--QQL-------QQQQLQQHLQQQQHMTQCMPQQT--------------------
-LQLAAPSSPSSKISCSPSSK-----------------------QTARRWCSKITRYFKC
RTTISWPSVSK---------------------------
>gi|148237620|ref|NP_001080612.	Xenopus laevis
-------------------MSRSP-------------VLKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGTVDKNKNKVTALQRYD-----------------------------------
---------------------------------------VSIDKSS-ESLSIGNGDNLQQ
-----------------ILTSDTPSPP----PGLSKPNPSAPISSANHSARSPF--EDAM
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTSSEWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-Q-----------------EDDLGFDPF-------------
----------------DITRKALADL-IEKELSVQDQPSLSPTSVQNPNPHL-APKGLSS
GFLH-------PTP-ASNANSIA-STFSVLPQ-RFPPF-HHRAV----YNSFSFPG----
------QAARYPWVAFP-RNNIMHLNHTANPTS------NSNFLD-LSHPPQ-----HNT
GLG--GITVADHSNSIEGLNMKEWQDGLKALLPNININFGGLSNASTPSNATHSAPTSNT
AT---TNSLNWDSSGSWMDPAIISGIPSSTGNGLES---LQDDNP-PHWLK--SLQALTE
MD-GP--SSSL------LPHHPHNNL-----FSAQIPLHR--------------GNWSP-
-Y--PPPSNPAS-FHSPPPGF-----------------------QTAFRPPTKTPTD---
---LLQSSALDRH-------------------------
>gi|114616137|ref|XP_001145650.	Pan troglodytes
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQRYD-----------------------------------
---------------------------------------TPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTSSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-P-----------------EDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSPTSLQNSSSHTTAAKGPGS
GFLH-------PAA-ATNANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFSFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPVADNSSSVESLNMKEWQDGLRALLPNININFGGLPN-SSPSNANHSAPTSNT
AT---TDSLSWDSPGSWTDPAIITGIPASSGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-GP--SAA-------PSQTHHSAP-----FSTQIPLHR--------------ASWNP-
-Y--PPPSNPSS-FHSPPPQIYYRVQHWTAIRQRGATIRKCRICPTLFSPSQPTTHSSLL
ISYVLKNPVPDQFFFSLTPDAMRSQGHYHLFINCKNFC
>gi|94734287|emb|CAK05025.1|	Danio rerio
-------------------MSCSP-------------EVKEDPME-------C-------
--------------PLCMEPLEIDD---------------------------------VN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKITEN---RKHLSSVRVVQRNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKSMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKTNP-----------------------
-NFLQSSTGTGEKTKSKSGTSQSSNSNSKEAWPSLQTTGKMPN-----GLSEHHKTPPLD
GGSDSENMTPDGLDSDLGLGSITGLPSFTSNCEPV----SPTSKPS-DSISLSNGETS-Q
-----------------ISGNDSPSPP----PGLSKPSLVVPNCVAGLTVRSPF--EGAA
AESQSLF-SDNSNFRHPNPIPSG-LPGFPNS-------LHNNSDWPTAPEPQSLFTSDTI
PVSSSTDWQAAFGFGSSTKQQ-----------------DDDLGFDPF-------------
----------------DVTRKALADL-IENELTVEDSFPMTITKSAPVMPH-----GPLL
GPLHNAPSIKSPLQ-PPTSSHF--APNSSLPS-RGFSHLPHRTV----YNSFSFPG----
----QAQSSRHSWMGMPMRNNLPHLNHSTGPSSA---AQHSSFLD-LNLAPQQQH-HHST
GLG--GIHMTENSTSVESLNVKEWQDGLRALLPNININFGGLPNSSSSSSSSSSSSSSMN
HTGGISHSLSWDGTASWMDPAIITGIPASSGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-VPSGSTV-------PPQPPHSGP-----FGAQFP-HR--------------AGWSP-
-YPTTATANPATQFHSPPPGF-----------------------QTAFRASAQASTD---
---LLQSAGMERH-------------------------
>gi|37590150|gb|AAH58778.1|	Mus musculus
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQ--------------------------------------
---------------------------------------SPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTPSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-P-----------------EDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSPTSLQNASSHTTTAKGPGS
GFLH-------SAA-PTNANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFGFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPIADNNSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNT
AT---TDSVSWDSPGSWTDPAIITGIPASSGNTLDS---IQDDNP-PHWLK--SLQALTE
MD-GP--SAA-------SSQPHHSAP-----FSTQIPLHR--------------ASWNP-
-Y--PPPSNPSS-FHSPPPGF-----------------------QTAFRPPSKTPTD---
---LLQSSTLDRH-------------------------
>gi|50290813|ref|XP_447839.1|	Candida glabrata
MINPHVQENLQAIQNTLSNYDTSF-------------LSEDEEDY-------C-------
--------------PLCIEPMDITD---------------------------------KN
FFPCPCGYQICQFCYNNIRQNPE---LNGRC------------PACRRKFDDE--SVRYV
VLTPEELK---MERAKLARKEKERKQREKEKKEYEQNN---RKHLAGTRVIQKNLVY--V
IGVNPPVPPEE---------VAATLKSDKYFG--------QYGKINKIVVNRKAPHGGS-
NNDHYHHHAPGYGVYITFSSKDDAARCIAQVDGTYMDG----------RLIKAAY-GTTK
YCSSYLKGMVCPNP--NCMF------LHEPGEEVDASNKRELSK----------------
--------------------PQLHTQNSM-------------------------------
-NSGSFRNG---------------------------------------------------
---------------------------------------SEFGSAAASPLPLKAHLNSAT
SSV--------------AANNDSSAST----PVLT-------------------------
----------------PAPAPPSTSNPWGISQ------TASAIANINLSKPNSSINLPTL
----------------NDN-----------------------------------------
---------------------------VTQDNDNNNEVPSKPKPVSNTNTSSSKKKNSSK
EYVD-------PYDALNGCITFMNERFKSLSNYQNKTFSLRSDA----IDQETLKS----
----------YPPLF---TASNIKISETSENIL------TQKLVEILAIKPT--------
----------------------DYSQSVIQFLQSVSASQPELINLPSVQSFTSANNAQAT
QT-------------------PINNPINPNLAQLGNGGVMGPGTPGPQNVMLQAMQPPQQ
MQAQP------------PQQM------------QQMPMNMG-------------GNANG-
-MFVSPQELAQKQAQPQMAQM----------------------------QSNNVGSNDLL
NQLISGKRLAAAN-------------------------
>gi|47224425|emb|CAG08675.1|	Tetraodon nigroviridis
-------------------MSHSP-------------DMKDDPME-------C-------
--------------PLCMEPLEIDD---------------------------------VN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEDIQ----------RIKNEKKQKQNEKKQKVTEN---RKHLASVRVVQRNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------RFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKSMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQDLYKINP-----------------------
-SFLQPPACGTEKTKNKTNSTQRYFLVC--------------------------------
---------------------------------------SLTVWTS-CILSLSLCLSLCQ
-----------------IPPSDSPSPP----PGLTKPSLVVPISVSDLTARSPF--EGAA
AESQSLF-SDNSNFRHPNPLPAG-LPPFPTS-------PRSSSDWPMTPEPQSLFTSETI
PVSSSTDWQAAFGFGSSSKQQ-----------------DDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQSPTSPGPFSQ-----------GG
GLPP-------PPN-PSASHHFP-SSLPRLPQ-L-----HHRPV----YNSFSFPSGQNS
QASQQQAATRHPWMGVPTRNNLAHLNHSAGAVS------HSNFLD-LNLPPQ-----HNT
GLG--GIPIS--------------------------------------------------
------------------------GIPAAAGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-GPAGSAVP------TPQPLHTGL-----LDAHLPLHHRAA-----------GGWAP-
-YLPPPTANPASQFHSPPPGF-----------------------QTAFRPPGQPSTE---
---LLQSAAVDRH-------------------------
>gi|4097898|gb|AAD00179.1|	Homo sapiens
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQRYD-----------------------------------
---------------------------------------TPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSSHRH----PVTGLQHQNHRASSHQKQSQYH
PLQTGKQLLALVLLNNQR---------------------DDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSPTSLQNSSSHTTTAKGPGS
GFLH-------PAA-ATNANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFSFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPVA--------------------------------------------------
------------------------GIPASSGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-GP--SAA-------PSQTHHSAP-----FSTQIPLHR--------------ASWNP-
-Y--PPPSNPSS-FHSPPPGF-----------------------QTAFRPPSKTPTD---
---LLQSSTLDRH-------------------------
>gi|150866819|ref|XP_001386542.	Pichia stipitis
-----------------MVPSDDS-------------FISDNEEEY------C-------
--------------PLCVEEMDISD---------------------------------KN
FKPCPCGYQICQFCYNNIKQNPE---LNGRC------------PGCRRLYDDE--SVEYK
TISAEEYR---LQQLKKEKREREKKQREKEKKETEMAN---KKHLAGLRVVQKNLVY--V
TGLNPPCNPED---------LHSVLRSDKYFG--------QYGKISKIVINTKTPTASG-
--SHHHHQNPGLVVYVTFAKKEDALKCINELDGSLCDG----------RVLRAAH-GTTK
YCSSYLRGHPCPNP--NCMF------LHEPGEEADSYTRKDLST----------------
--------------------QQGIKMSM--------------------------------
-------MGLVSSSSNISNS----------------------------------------
-----------------------------------------------GHFQAHSATNSQS
-----------------NYSGDEDTSSG---PIL--------------------------
--------------------PA--SVQWAKAG------SNSASNSPSVNNNTPLANSAAF
PT-----------LGEIFR-----------------------------------------
----------------DQKSQQKKDLKQKIKSKVSKDNVLLPDDID-------IDDDSVL
GFID-------STS----------ECLRDLQQ-RKEKLNVHFSK----LSNR--------
------TGSVLPLFAFNSTEGLSHDTRLEEETL-----LARQVIERFFLRPI-----KNY
HLAYQNHPIAQQQTLQNQIQQQQQQQQQR-------------------------------
------------------------QQPGFQAASLEQ---LQADQQ-RKLLEAQQVEGSAI
SQ-QQAQQQLLLLQ---LQQQQQQSQ-----QANQINMLRATERGNTST-----PPPPG-
-LFAANSNAPVA---APAAGA-------------------------------QSSSSQLL
TQLMSGKR------------------------------
>gi|45187809|ref|NP_984032.1|	Ashbya gossypii
MENPHVHDNLQHIQAVLSNYDTSF-------------LSDDEEDY-------C-------
--------------PLCMEPLDITD---------------------------------KN
FKPCPCGYQICQFCYNNIRQNPE---LNGRC------------PACRRKYDDE--SVEYI
VLSPEELK---LERAKQARKERERKQREKERKENEYAN---RKHLAGMRVIQKNLVY--V
IGLNPPVPYEE---------VGALLRSDKYFG--------QYGKINKIVVNRKTGHND--
-------HQTGYGIYVTFSRKEDAARCIQAVDGTFMDG----------RQVKAAY-GTTK
YCSSYLRGQSCPNP--NCMF------LHEPGEEADSFNKRELSGKQQPHQQPGQQLHQHG
SQHLPSQLQSSVHQPAQVHVHQLNAQPHIHHPSPFKG-----------------------
----PHNSGAAASNNSNGA-----------------------------------------
---------------------------------------SAVPSPA----QAKAQLHMDD
-----------------SSSSSTPAAHT---PILT-------------------------
----------------PAPLPTG-ANPWGITQ------SSTPVSALSKVSSSTAF-----
------------------------------------------------------------
--------------------PTLGEA-INTPAPTFNGVQAAASSYNQNGSSKNKKNNDTK
NYED-------PYDPLCSAVKFIDDTIAFLSDYKCVSYNLRSGL----IDDATYAS----
---------------YPSLFSFSNIDVSAESEG----ILGRKLIDMLAVKPW--------
-------------------------DQVAATFPAVNEMSPQLQRQVLRQQQMATTPKQQ-
------------------------QLVQMQRNNPDP---NSQVSP-TSQLQ--QQQLQHS
HS-QS------------QQEPPQEPP-----FSQQQQHRTVVH-----------TPPPG-
-M--FVQNGQMSQTQSVPHMV---------------------------AQTRSNNSTDLL
NQLINGKKVTAGT-------------------------
>gi|157014047|gb|EAA43539.4|	Anopheles gambiae
-------------------SMMNN-------------SSGDEQVE-------C-------
--------------PLCMEPLEVDD---------------------------------LN
FYPCTCGYQICRFCWHRIRTDE-----NELC------------PACRKAYPEN--PADFT
PLSQEQIA----------AFKAEKRQRDQQRRAKISEN---RKHLANVRVVQKNLVF--V
VGLPPRLADPE------------ILKKHEYFG--------KYGKIHKVVINPSTTYAGV-
-------QGPSASAYVTYINNNDALRAIQSVNNIMIDG----------RLIKTSL-GTTK
YCSHFMKNQTCPKP--DCMY------LHELGDQEASFTKEEMHQGK--------------
--------------------HQEYEKRLHDAMQAQLGLTSAAG-----------------
-GHGSNGSGSAAATAATAASSGGVVAASATTAAAAVAAGTTAGASSTLVVNGGSAGSAGS
GGGSGESGVPSDIKQISDITNGPIP--------------SKEAWPSLSTTPVGGSAHGGG
-----------------SSNKENKLNGK---TGVAGNKENSNRSDRKHETKSRS--KGGK
NKQQQQQ-QQQ---QHNNK----------NS-------HDNSSNHKDSTSNQQRNGASNA
P--EAHEHAIVNGNSKEAQNN-----------------SKNLKQQQR-------------
----------------EREREQREQQSLLKGSSDSGEQQQQQKQQQPPQSKKREANGTSN
GPTA-------TSISNGNANGNGHIINNDLDD-DDDELDFEDLD----NDALSSDN----
--DGKTDSPSLSSSASS-RNGVDSETASGKSTP-------GAFVDTLNNGDSNVI-DAGA
SV---GDAVASKTDACETNAIPAASDG-----------------DAADSNRSSSSPSSSS
SM-----------GDEKADSESTAPVASSSSTTTSLYGGLDDGTDTTAAVISATMGKLSV
TD-TTASNGGI------MNHKFANEL-----IDLSARYGKLESILDDNSSFFSYNTFDP-
-YGKPSAAGSTDLGVDSVSG----------------------------NQSVGLTSSQLP
DLLSGTNDTNEQHAKELLKNMGN---------------
>gi|28373260|gb|AAF66693.2|	Candida albicans
-----------------MIQADDT-------------FISDDEEEY------C-------
--------------PLCVEEMDISD---------------------------------KN
FKPCPCGYQICQFCYNNIRQNPE---LNGRC------------PGCRRLYDDE--SVEYK
TVSAEEYK---LMQLKKEKRDREKKQKEKEKKEMEMVN---KKHLAGLRVVQKNLVY--V
TGLNPPCNPDD---------LHSVLRSDKYFG--------QYGKISKIVINKKTPTTQT-
--STHHHQNPGLVVYVTFTRKEDALRCITELDGSLCDG----------RVLRAAH-GTTK
YCSSYLRGQPCPNP--NCMF------LHEPGEEADSYTRKDLST----------------
--------------------QQGIKMGMTA------------------------------
-RSHTTSFGEESSNNS--------------------------------------------
-----------------------------------------------QSNQAGSDDDHHE
-----------------AHK-----------EHL--------------------------
--------------------PST--AHWAAAG------TTSGSNSPSVNNNIPLANSAAF
PTLGE-------------------------------------------------------
---------------------------IVRDQKQQQKKETKPRSKTTKSNNTLVPDELDA
G--------------DNSVFKFVETTTEQLRG-----LEDIRNVRFKGFD----------
------NGKILPLFSF--KGNFSNDTQLEEEKV-----IARQVIEKFLLRPL-----KNY
HLAYQNHPITQQQAILQRQQQQQQQQQQQ-------------------------------
------------------------QTPALQVAQLQQNKNDEQQKQAQQQLLLLQLQHQQQ
LQQQQ--QQR-------QLQQQQNQPHQLNILKTSDRVNT--------------STPPPP
GLFAGKDVAASSDMSNTGAPL-------------------------------PSSSSQLL
TQLMSGKR------------------------------
>gi|115304953|gb|AAI23840.1|	Bos taurus
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQ--------------------------------------
---------------------------------------SPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPST-------PQTSSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-P-----------------EDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSPTSLQNSSSHTTTAKGPGS
GFLH-------PAA-PTNANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFSFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPIA--------------------------------------------------
------------------------GIPASSGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-GP--TAP-------PSQTHHSAP-----FSTQIPLHR--------------ASWNP-
-Y--PPPSNPSS-FHSPPPGF-----------------------QTAFRPPSKTPTD---
---LLQSSTLDRH-------------------------
>gi|73978617|ref|XP_539824.2|	Canis familiaris
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQRPQSKTKLLYKHLYNCCCSRRGLQMEYRHKPPLKEWGS
DVNHHMQGILSKDY-------------------------GPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTSSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-P-----------------EDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSPTSLQNSSSHTTTAKGPGS
GFLH-------PAA-PTNANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFSFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPIADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNP
AT---TDSLSWDSPGSWTDPAIITGIPATSGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-GP--SAA-------PSQTHHSAP-----FSTQIPLHR--------------ASWNP-
-Y--PPPSNPSS-FHSPPPGF-----------------------QTAFRPPSKTPTD---
---LLQSSTLDRH-------------------------
>gi|126325142|ref|XP_001376424.	Monodelphis domestica
----------------MEGLKKGP-------------EVLEELL--------CSEEAMRK
AGVAHSKSSKDMENHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQSSVSDPMNALQNLT
GGPPAGATGIGMASRGPGQSLGG---ISGLGGVGQPMTLSGQPPPGTSAMPPHGMSVVSA
TIQPTQLQLQQVALQQQQQQQQQQQQQQQQQQQQQFQA---QQQVALQQQQQQQQQQ--Q
QQQQQQFQAQQ----------SAMQQQQQQFQVAVQ----QQQQQLQVAVQQQQQHLLKF
HHQSQQQLQQQQQLRIAQLQLHQQQQQQQQQQQAALQAQPPPQPPPPSQAMQQQL-QQLH
HQQQHHPAQPPPQPPPPQVSQGQQPPLPPQAPPAQPLVSQAQSLSG--------------
--------------------QMMLTPQQLKAMQAQQAQAQA-------------------
-QAQAQAQAQQQQQQQQVAAAQAAQV----------------------------------
---------------------------------------AQMAAAAAAMMTAAMPRGGMQ
-----------------IRPRFPPAAAGSATP---------PITIPLGGQPTPQVSQGSM
AM-----------MSSPSPVQQAQTPQAMPP-------PPQPSPQPGQPSSQPNSNVSSG
PAPSPSSFLPSPSPQPSQS-P-----------------ASARTPQTF-------------
----------------SVPSPGPLNT------------PVNPSSVLSPASSSQAEEQQYL
EKLK-------QLSKYIEPLRRMINKIDKNEE-RKKDLSKMKSL----LDILTDPS----
--------KRCPLKTLQ-KCEIALEKLKNDMAV-------------PTPPPP--------
-----PVPPTKQQYLCQPL-LDAVLANIRSPVFNHSLYRTFVPAMEAIHGPPITAPIISP
RK------RKYEEDEKQTIPNVLQGEVARLNPKF-----LVNLNP-SHCSNNGTVHLICK
LD-DKNLPSV-------PPLELSVPAD----YPAQSPLWIDKHWQY--------GAFXF-
-LQSVHQYMTSKLLQLPDKHS---------------------VTALLNTWAQSIRQACLS
AA------------------------------------
>gi|73978621|ref|XP_859681.1|	Canis familiaris
-------------------MSRSP-------------DAKEDPVE-------C-------
--------------PLCMEPLEIDD---------------------------------IN
FFPCTCGYQICRFCWHRIRTDE-----NGLC------------PACRKPYPED--PAVYK
PLSQEELQ----------RIKNEKKQKQNERKQKISEN---RKHLASVRVVQKNLVF--V
VGLSQRLADPE------------VLKRPEYFG--------KFGKIHKVVINNSTSYAGS-
-------QGPSASAYVTYIRSEDALRAIQCVNNVVVDG----------RTLKASL-GTTK
YCSYFLKNMQCPKP--DCMY------LHELGDEAASFTKEEMQAGK--------------
--------------------HQEYEQKLLQELYKLNP-----------------------
-NFLQLSTGSVDKNKNKVTPLQ--------------------------------------
---------------------------------------SPIDKPS-DSLSIGNGDNSQQ
-----------------ISNSDTPSPP----PGLSKSNPVIPISSSNHSARSPF--EGAV
TESQSLF-SDN--FRHPNPIPSG-LPPFPSS-------PQTSSDWPTAPEPQSLFTSETI
PVSSSTDWQAAFGFGSSKQ-P-----------------EDDLGFDPF-------------
----------------DVTRKALADL-IEKELSVQDQPSLSPTSLQNSSSHTTTAKGPGS
GFLH-------PAA-PTNANSLN-STFSVLPQ-RFPQFQQHRAV----YNSFSFPG----
------QAARYPWMAFP-RNSIMHLNHTANPTS------NSNFLD-LNLPPQ-----HNT
GLG--GIPIA--------------------------------------------------
------------------------GIPATSGNSLDS---LQDDNP-PHWLK--SLQALTE
MD-GP--SAA-------PSQTHHSAP-----FSTQIPLHR--------------ASWNP-
-Y--PPPSNPSS-FHSPPPGF-----------------------QTAFRPPSKTPTD---
---LLQSSTLDRH-------------------------
