>gi|21355331|ref|NP_648315.1|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASFFNVGAL-G
N---VFSTPV------GQRI----------------------------------------
------------------------------EAATDANLA-SENWAANMEICDMINESS-D
TARDAMRAIRKRLSQNAGKNNQVVMYTLTVLETCVKNCGKAFHVLVAQKDFINE-LVKLI
GPKN---DPPAAMQEKVLSLIQIWAD-AF----KNQPDLNGVTQMYMELKNKGI------
-EF---P-----ANDLDAMAPI---YTPQRSVPEMPPQLVAA---------QQHTISPQH
MAAAAAAAAAAAAPPSTGPLH--------LTPEQAAKLRSELEIVSNNMSIL--SEMLSV
LKPG-------QESPDDYALLNELTSTCK-EMQSR----IVDLIGR-VQ-DDELTAEFLR
INDELNNVFLRHQRYEKNRS-------------QGQGAGVTSPSAVLGAAMGLPGVGAAG
AGA--------TTVATLPPPPTTTAVSN---------TPQSDQLLIDLIESSEEAQLPQS
----LGQISLGGGAP-----IGVQRSAR------------PADEFDMLAQS---------
------RTDGNHKSDLLRDIPSVDAAAGSVTA--------TASPYKPNQPQQAQRSA---
----------GEPPVVSKSTKENEID---------------------------EMEAWLG
SSHIEGIEELTSS------------------EFDKFLEERAAAAENLPTISASNSAASAT
TGSAGADSLRKT-------PKKPGAEEDLLAL----------
>gi|4507249|ref|NP_003464.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPLFAT
N---PFDQDV--------------------------------------------------
------------------------------EKATSEMNT-AEDWGLILDICDKVGQSR-T
GPKDCLRSIMRRVNH---KDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASE-VSNVL
NKGH------PKVCEKLKALMVEWTD-EF----KNDPQLSLISAMIKNLKEQGV------
-TF---PAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIE------LSLKEQRQQ
-STTLSTLYPSTSSLLTNHQH----------EGRKVRAIYDFEAAEDNELTFKAGEIITV
LDDS-DPNWWKGETHQGIGLFPSNFVTADLTAEPE----MIKTEKKTVQFSDDVQVETI-
-EPEPEPAFIDEDKMDQLLQ-----------MLQST-----DPSDDQPDL----------
-----------PELLHLEAMCHQMGPLI------DEKLEDIDRKHSELSELNVKVMEALS
----LYTKLMNEDPM-----YSMYAKLQ-------------NQPYYMQSS----------
------GVSGSQVYAGPPPSGAYLVAGNAQMS--------HLQSYSLPPEQLSSLSQAVV
PP--------SANPALPSQQTQAAYPNTMVSSV--------------------QGNTYPS
QAPVYSPPPAATAAAAT-------------ADVTLYQNAGPNMP-QVPNYNLTSSTLPQP
GGSQQPPQ-----------PQQPYSQKALL------------
>gi|126341511|ref|XP_001377289.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPLFAT
N---PFDQDV--------------------------------------------------
------------------------------EKATSEMNT-AEDWGLILDICDKVGQSR-T
GPKDCLRSIMKRVNH---KDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASE-VSNVL
NKGH------PKVCEKLKALMVEWTD-EF----KNDPQLSLISAMIKNLKEQGV------
-TF---PAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIE------LSLKEQRQQ
-PTTLSSLYPSTSSLLTNHQH----------EGRKVRAIYDFEAAEDNELTFKAGEIITV
LDDS-DPNWWKGETHQGIGLFPSNFVTADLSAEPE----MIKTEKKTVQFSDEVQVETI-
-EPEPEPVYIDEDKMDQLLQ-----------MLQSA-----DPNDDQPDL----------
-----------PELLHLEAICHQMGPLI------DEKLEDIDRKHSELSELNVKVMEALS
----LYNKLMNEDPM-----YSMYAKLQ-------------NQQYYMQS-P---------
------GISGTQVYPGQPQSGAYLVAGGTQMG--------HLQSYSLPPEQISSLSQGAV
PP--------SANPALPSQQAQTSYPNTMVSSV--------------------QGNTYPN
QASVYSPPPAAAAAAAT--------------DVTIYQNAGTSMS-QVPNYNLASSTLPQP
PGNQQPPQ-----------AQQTYSQKALL------------
>gi|74201485|dbj|BAE26170.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPLFAT
N---PFDQDV--------------------------------------------------
------------------------------EKATSELNT-AEDWGLILDICDKVGQSR-T
GPKDCLRSIMRRVNH---KDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASE-VSNVL
NKGH------PKVCEKLKALMVEWTD-EF----KNDPQLSLISAMIKNLKEQGV------
-TF---PAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIE------LSLKEQRQQ
-SAPVSTLYPSTSNLLTNHQH----------EGRKVRAVYDFEAAEDNELTFKAGEIITV
LDDS-DPNWWKGETHQGVGLFPSNFVTADLTAEPE----MIKTEKKTVQFNDDVQIETI-
-EPEPEPAFIDEDKMDQLLQ-----------MLQST-----DPSDNQPDL----------
-----------PELLHLEAMCHQMGPLI------DEKLEDIDRKHSELSELNVKVMEALS
----LYTKLMNEDPM-----YSMYAKLQ-------------SQQYYLQSS----------
------AVSASQVYPGPAQSGTYLVAGSAQMT--------HLQSYSLPPEQLSSISQGAV
PS--------SANQALPSQQTQASYPNAMVSSV--------------------QGNSYPS
QASIYSPPPAAAAAAAAVVPVPVPAAVPVPADVTIYQNAGPTLS-QVPNYTLTSSTLPQT
GGSQQPPQ-----------PQQAYSQKALL------------
>gi|47220261|emb|CAG03295.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MFSIGEKMEFLFG
N---PFSTPV------GQRI----------------------------------------
------------------------------ERATSGLLQ-SEDWALNLEICDIINETE-D
GPRDSVKAIRRRIVGN--KSFREVMLALTVLETCVKNCGHRFHVLVASQEFVEGVLVQAI
LPKN---NPPTALHERVLSLIQSWAD-AF----RSSPSLVGVVCVYDDLRRRGL------
-EF---P-----MTDLDAMSPI---HTPNRSIPENGGPEAPPGVT------CTRQSPPQT
-PASVPSQNSSPPVHPGGGPL-------SLSPQQEAKLRHELALVKGNLTVM--SEMLNE
LIPG-QSQ--KDDAQCCRCVFKQLYSVCK-NMQTR----VVELIPQ--LEDEGFIEELLM
VNDDLNNAFIRYERFDRLNK-----------AQTPN-----IQQDSTTE-----------
-----------PTLVDLSPEPPTLTQPA--------------------------VITPTV
----QAEVSATTESR-----QPTKPSTQ------------REEEFDMFAQTRG-S-----
------SLAEQRKSVRYEDPGAVEGLAGALDT--------RLQVTGGVC-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------
>gi|149630101|ref|XP_001520257.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------MTICLIFHKVRSVTGRKGARRDWGFRAVELEITTAGLGGRDPATFSVS
R---PSRDPIPMLRGPGRGMFLQPPARKTFRFSHPRPRVWHYTPTPNGLFRPHLTPRPDG
GLRILPLSRSTNEEQRKPTWRPSRLTFHRQEKATDGALQ-AEDWALNMEICDIINETE-E
GPKDAFRAVKKRIVGN--KNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVEGVLVRTI
LPKN---NPPAVVHDKVLNLIQSWAD-AF----RSSPDLTGVVAVYEDLRRKGL------
-EF---P-----MTDLDMLSPI---HTPQRTVYSSDSQTGQNSP-------VSDAPQRGD
--SQLLPVAPLPPMPVPQDDT-----PILPTPEQIGKLRSELEVVNGNVKVM--SEMLTE
LVPG-------QAEPADVELLQDLNRTCK-AMQRR----VLELIPR-VL-NEQLTEELLI
VNDNLNNVFLRHERFERFRT-----------VQSAK-----VPSEVECA-----------
-----------TSLIDMGPGLAAASNQS-----------------------EAPGNLSSQ
----LAGMNLGSDSV-----SAGLQSLE--------PPAKLEEEFDMFAFTRSS------
------SLADQRKEVKYEDPQATDGLAGALDA--------RQQSTGAVRTKAGMEGS---
----------PEHNLNNWMVKQGMIPVTQACLM-------------------EDIEQWLS
-TDVGSEAEDSQGVTSE--------------EFDKFLEDRAKAAERLPNLPSPPAGPPSP
PPSSAPR------------KKQKEKEDDALFAL---------
>gi|125977150|ref|XP_001352608.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASFFNVGAL-G
N---VFSTPV------GQRI----------------------------------------
------------------------------EAATDANLA-SENWAANMEICDMINESS-D
TARDAMRAIRKRLSQNAGKNNQVVMFTLTVLETCVKNCGKAFHVLVAQKDFINE-LVKLI
GPKN---DPPAAMQKKVLSLIQIWAD-AF----KNQPDLNGVTQMYMELKNKGI------
-EF---P-----VADLDAMAPI---YTPQRSVPEVHPHPQL----------MAAHTVSPQ
-HVAAVTAAAAAAPPSTGPLH--------LTPEQGAKLRSELEIVTNNMSIL--SEMLSV
LKPG-------QETPDDYALLNELTSTCK-EMQSR----IVDLIGR-VQ-DDELTAEFLR
INDELNNLFLRHQRYEKTRS-----------QGLGGGAVVTSPSAVLGAAMGLPGVTPGT
G----------AVVASLPPPPSATAAAA---VSNTPQSDQLLIDLIESSEEQQLQQIPQS
----FGQLSLAAGSG-----AAAAPRGA-------------ADEFDMLAQS---------
------RTDGNHKTDLLRDIPSVDAAAGSVGG--------VASPYKQPQKQQQPQQQPLR
AA--------GEPPVVSKSTKENEID---------------------------EMEAWLG
SSDVDGIEELTSS------------------EFDKFLEERAAAAENLPTINASNSAASAT
NTNTTGSGGDSLRKT----PKKPGADEDLLAL----------
>gi|50309817|ref|XP_454922.1|	Kluyveromyces lactis
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MMSIHLDEGPVRRM
Q---PQSDPL------TRKI----------------------------------------
------------------------------QRACRISLP-EPDLALNLDVADYINDKQGA
APREAAISIVRLINS---RDTHTAIFALSLLDVLVKNCGYPFHLQISRKEFLNE-LVKRF
PERP--PVRFSKVQRLILTAIEEWYQ-TICKHSAYKEDMGYIRDMHRLLKYKGY------
-TFPKIN-----SEDLAVLKPSEHLKTPSEI---QKEQEIAQAAK------LEELIRRGK
-PEDLREANKLMKVMAGFKED--------NMIQSKQILNEELTKLRRKADLL--NEMLGT
NDSP-DI---ENE------TIVELYNALR-SSQPR----FQKIIEE-EHDDDEFVQDLLK
FNDTVNQLVQKYDLLKAGHA-----------GEANQ-----INVDNISSSVNNGGALANE
-----------INLIDFDDEEVNKSSSS----NSTAAAARNNLEDDLLSGLNDLNFSDNN
----NNNNNFGFGGS-----IALDTAAHASPAVPVTTTTTTNSNFDLLS-----------
--------------DLSSPSPVQAQQDTHSND--------LLSEFSAPAVQHSTQPSIVS
DR--------FLVNQSDVLKFEFAISRESESTI--------------------KVTSFFS
NVSISQLTDLTLML-----------AVPKAQQLRLLPQSNTVLS-SYAKDGIHQKSWIDN
AVKNAPKPLRVKWKVSYKANGVPKEESAVYTFPNV-------
>gi|115497944|ref|NP_001069574.	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPLFTA
N---PFEQDV--------------------------------------------------
------------------------------EKATNEYNT-TEDWSLIMDICDKVGSTP-N
GAKDCLKAIMKRVNH---KVPHVALQALTLLGACVANCGKIFHLEVCSRDFATE-VRAVI
KNKA-----HPKVCEKLKSLMVEWSE-EF----QKDPQFSLISATIKSMKEEGI------
-TF---P-----PSGSQTVSAA--AKNGTSSNKNKEDEDIAKAIE------LSLQEQKQQ
-HTETKSLYPSAEIQSNNKVA------------RKVRALYDFEAVEDNELTFKHGEIIIV
LDDS-DANWWKGENHRGIGLFPSNFVTCNLNIESE-----AAVDKLNIIDDEEEEIK---
-KSEPEPVYIDEDKMDRALQ-----------VLQSI-----DPTDSKPDS----------
-----------QDLLDLEDICQQMGRMI------DEKLEEIDRKHSELSELNVKVLEALE
----LYNKLMNEAPV-----YAVYSKIH-------------HPAHYPTS-S---------
------AGVPIQTYPVQPHGGNYMGQSIHQVT--------VAQSYSLGPDQIGPLRS--L
PP--------TVNSSVTTQPAQTPYLSTGQDTI--------------------SNPTYMN
QNSNLQSAPGAAAYTQQ---------MGMSVDMSSYQNATSNLP-QLAGFPVAVPAHSVA
Q------------------QQTNYHQQQPLL-----------
>gi|157109301|ref|XP_001650612.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MASFFNVGALGG
N---PFSTPV------GQRI----------------------------------------
------------------------------EQATDASLA-SENWALNMEICDLINESS-D
GARDAMKAIRKRLVQNAGKNYTVIMYTLTVLETCVKNCGKAFHVLVANKEFIQE-LVKLI
GPKN---DPPPIVQEKVLSLIQIWAD-AF----RSQQDLNGVVQVYQELKNKGI------
-EF---P-----ATDLDSLAPI---YTPQRSVPDGAATDNTMSVS-------------PH
-HASQTPNSPAMPPPSSMSQD------------QIAKLQSELDIVTMNMTVL--GDMLTE
LKPG-------QEDPSDYQLLTELASTCR-EMQSR----IVELIGK-VN-HDELTAELLR
LNDELNLLFVRHARFEKNRD-----------PKTASST---TPSAILGAAMGVPTDLVAS
TGGADKK----ESLIDLSDEASGGGGAA-----LSTQLAGLSLAGTGTTASSQLSQLSS-
----VPAQSGATTGS-----SSTKKSIP---------PDVVSDEFDMFA-----------
----------------------------------------QSRNTTGDTAKDTAKLNQPG
QP--------KTTPLD-------------------------------------DLENLDP
SSGSGNGGGPEESLTSK--------------EFEKFLAERAAVADNLPSI----SSQIGG
GGPNSASK-----------GGKKKEEEGLLAL----------
>gi|83766841|dbj|BAE56981.1|	Aspergillus oryzae
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------MAARDRFGAYADLGL
T---PLQRAI--------------------------------------------------
------------------------------RHACDISHY-EPNLALNLEVADLINSKKGN
APREAALEIVRLINS---RNQNVSLLALALLDICVKNCGYPFHLQISTKEFLNE-LVRRF
PERP--ALRPSRVQHRILESIEEWRQ-TICQTSRYKEDLGHIRDMHRLLLYKGY------
-VFPEIR-----NEDAAVLNPS---DNLRSAEEMEEEEREAQSAK------LQELIRRGT
-PADLQEANRLMKVMAGYDNR--------HKTDYRAKAAEEVAKVQQKAKIL--EEMLQS
QQPG--------ERIAEGDVFEELANALQ-SAHPK----IQKMCEE-ESDDPEAVHKLLE
INDSIHRTIERYKLVKKGDV-----------EAASR-----IPKGTLGTTTGVSKNANNE
-----------LSLIDFDPEPSSNGNTS----------QPAGGSSLENDLLGLSIDEPAP
----AGGISLGPGPV-----TPMPSSTP----PIQQAPSAFKPNYDILSSLNSSRPASQS
SIPAPAAMRPQSTTATPPPSDPFASLVSASPR--------HPRASSPQPAAGNTKAADED
EW--------DFTSSLPESNALPTTNRVQVLNS-----SLRVEFVARRHPQQARQIHMVA
LFSNGTNQPLSELHFQV--------AVEKAYTLQLRPQSGRDIA-PLQANGVQQEMLVSG
VEAGKGNSIKMRFKVSYRVGNEQKEEQGMVPSLGIA------
>gi|62858863|ref|NP_001016968.1	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MEE
E---SLEVRI--------------------------------------------------
------------------------------NRATNPLNK-EQDWEGVQAFCDQLNQEL-E
GPQLATRLLAHKIQS---PQEWEAMQALTVLEACMKSCGKRFHSEVGKFRFLNE-LIKVV
SPKYLGSRSPEKVKLKILELLYSWTL-GL-------PGEVKIAEAYQMLKKQGIIKE--D
PKL---P-----PDALIPPPPP----RAKNAIFDDDEKSKM----------LARLLKSTH
-PEDLRAANKLIKEMVQEDQK---------RMEKISKRVNAIEEVNNNVRLL--GDMLST
YKAG-------QTSEGSEDLMKELYQRCE-KMRPT----LFRLASD-TEDNDEALAEILQ
ANDSLTQVINQYRQVVKGEE------------VNGEAASSSLPASSSALLDLSGLDMMAA
ATPLYPSAPAQPLQSSFGPPAQATNSMS----LLDDELMSLGLNDPVASAHPLESSAWNN
----FQSPETNPPVS-----NEKVASSH---PQPVSQGSKALEDLDLLGKTLLQQ-----
------SLPPTAQQVRWEKPNQKPTLRDLQTK--------NTHSSHAPQPIVGQSVGGEQ
PALSPEKKEISLANISVPLESIRPSCILPVIVYDQRSFRVLFHFAKDPPPGRPDVLVVVI
SMLSTAPLPVTEISFQA--------AVPKTMKVKLQPASGNELPSFNPILPPSSVTQVLL
LANPTQEKVRLRYKLTYTQGDQTFDEMGDVEDFPPVEKWGDL
>gi|91089923|ref|XP_972937.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MDLVTQ
T---SLEALL--------------------------------------------------
------------------------------LKATNSQNQ-NIDTAAVEAFCALVNKEK-D
GAHIGVKVIANRLPS---GNEKELLQTLNILDTCMSKCGTAFQSEVGKFRFLNE-MIKLV
SPKYLGSQTPLVVKQKVLQLMYIWTL-DY-------PKETKIKEAYDMLRKQGVIKEIPN
PNI---V--------QNANIPR---KKAANSVFQDEEKSKI----------LQKLLQSKD
-PEDIQAANWLIKSMVKEDDK---------RAELKSRRVSELESVQNNVRLL--NEMLDS
YKPG-ISS--ADELD----LIKELHQSCE-RLRPN----LMKLTAE-TQQNEEILGDVLQ
ASDELSQVFGKYNRI----------------IVQGVSVVD-DGSNALLDFEGADEAQCRN
-----------SDTKEIDVLCDIFNASN--IPDSADILKPVSVLTCDKNENGKEVNKFKA
----LEELDVLSEHFIKENLPTSRQGTFNKYESNLLVYTKLSETKPVQS------NGKNE
SISESLSLDLSYLISKPKDEPKTNTMENSTDDCLVDIADEKMLEAGETPQRKPSLTDPAK
NEI-------KLNDIFIKLEDIKPSPVPPLTIL-NERNGITITLHFVKDQPRDDVHVFVV
TTINKNEMPLTNYLFQA--------VVPKGCKVKLQPPSATTLPAYNPFLPPSAITQIML
IANPDDVQVFLKFFVSFVMDEETCTEIGEVETLPM-------
>gi|148232302|ref|NP_001085600.	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MEE
E---SLEVQI--------------------------------------------------
------------------------------NRATNPLNK-EQDWDGVQAFCDQLNQEL-E
GPQLATRLLAHKIQS---PQEWEAMQALTVLEACMKNCGKRFHSEVGKFRFLNE-LIKVV
SPKYLGSRSPEKVKLKILELLYSWTL-GL-------PSEVKISEAYQMLKKQGIVKE--D
PVL---P-----PDALIPPPPP----RAKNAIFDDDEK----SKM------LARLLKSTH
-PEDLRAANKLIKEMVQEDQK---------RMEKISKRVNAIEEVNNNVRLL--SDMLST
YKDG-QTS--EGSED----LMKELYQRCE-KMRPT----LFRLASD-TDDNDEALAEILQ
ANDSLTQVINQYRQVVKG-E-----------EVNGEAASSSLPASSSALLDLSGLDMTPA
ATPLYPSAPAQPLQSDFGPTAQASNSIS----LLDDELMSLGLNDPVASAQPLESSAWNN
----FQPPETMTPAS-----NEKVASSH--PQPPLTQGSKALEDLDILGKTLLQ-Q----
------SLPPTVHQVRWEKPSHKPTLRDLQTK--------NPPIAHASQSVVGQSVGGEQ
PARSPEKTEISLANVNVLLESIRPSCILPVIVYDQQSFRVLLHFAKDPPPGRPDVLVVVI
SMLSTAPLPVTGISFQA--------AVPKTMKVKLQPATGSELPPFNPILPPSSVTQVLL
LANPTQDKVRLRYRLTYIQGDQHFDEMGDVEDFPPVEKWGNL
>gi|125810127|ref|XP_686017.2|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MRLCDWPSHYCASVSQT
Q---SSTGPIVWPSRLCLSS----------------------------------------
-----------------------------TDKATHPTNR-QEDWEYIIGFCDQINKEL-E
GPQIAVRLLVHKFCA----QEWEALQALTVLEACMKNCGRRFHKEIARYRFLNE-LIKVV
SPMYMGNSISEKVKSKIIEMLYSWTV-AF-------PNEAKIAEAYQTLKRQGLVKS--D
PEL---T-----VDKTLIPSPP---ARPKNPVFDNEDMGKL----------LAELLRSKN
-PEDLQEANRLIKNMVKEDDA---------RVHKLTKRINTLEEVNNNVKLL--TEMLSQ
YDRE-RSS--DADRE----LIKELYERCD-KLRRT----AFKLATE-AEDNDSSLGDILK
ANDDLSRVISCYKRIVEGQADDGEAEELRPAANEATQKASSIPVLPPPPRRLAGAHGSQT
SSPNHKAAEHQSSLSLLDDELLSLGLNDPPSVPNRPKLDDLSAQWTSLQVAHTKLQIFRA
----VCGASGIAGGA-----FGQSAAVM--------CSAAPLSSSNPFV-----------
-------SAPLSGSPAVSRAQAVTGGSAPGSP--------FFQPFSSPSHSLQSSPARSS
EP--------SLTNLHVPLEAIRPSKVLPVTMYDKDGVRVLLHFAMDCPPGRPDVLVMVV
SLLNTAPLPVRNVVLQA--------AVPKSMRVKLQPPSGTEICPFNPILPPASITQVML
LANPLKERVRLRYKLAYLLGERQYSEVGELDQFPPADRWGSL
>gi|66535729|ref|XP_623539.1|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MGLFQT
S--SPFDADV--------------------------------------------------
------------------------------EKATSEKNI-SIEWGKMLDICDKVGTST-Q
NAKDCLRSIVKRLYS---PDPHIVMQALTLLDVCVINCGKTFHLEIASRDFEND-LRKLV
NHSE------PKIAEKMKELLKKWAENDF----KTDPQLNLIPSLYNKLKNEGH------
-DF---T-----STSDTPKRTTVLSKDPNVVTNSQEEEDIAKAIE------LSLKESKAH
NQASSSHNSPSTKYTSLYPNVSSALGTSSNAEGRKVRALYDFEAAEDNELTFFAGEIINI
LDDS-DPNWWKGSNQNGEGLFPSNFVTADLSVEPEQFTKLEHSNKKMVQFAEEVEVKTVK
REPEVVEVEIDERKMDRLLH-----------LLHEA-----DPQCDTSDT----------
-----------QEMLDLEEQVTAMGPLI------DAALEKVDRRHAQLTQLSSDLVDALN
----LYHTLMREPPPPTPSNYTLPKMPP------------HINPYQFQN-----------
--------------QGPPPPHIFNGV---------------------PPAHQTSFPVGGG
PSG-------PYNATIPTSDYMGSASMPNITL---------------------PQHFHMQ
PPGPHQPPPGHPQGQPV--------------------PEQSNLPYSHQGYPPQTGPMPGP
YGPPGPTGPPVS-------QQPQYAPPNGQHMM---------
>gi|157015984|gb|EAA44160.4|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------MTSFFNVGALGG
N---PFSTPV------GQKV----------------------------------------
------------------------------EQATDASLA-SENWALNMEICDMINESS-D
GARDAMKAIRKRLTQNAGKNYTVIMYTLTVLETCVKNCGKAFHVLVANKEFIQE-LVKLI
GPKN---DPPPIVQEKVLSLIQIWAD-AF----RSQPDLNGVVQVYQELKNKGI------
-EF---P-----ATDLDAIAPI---YTPQRSVPDGAPATESANTL--------PVSPHHH
-HASQTPGSPAMPPPSSMSQD------------QIAKLQSELDIVAMNMSIL--GEMLTE
LKPG-------QEDAADYKLLTDLTSTCR-EMQNR----IVDLIGK-VQ-HDELTAELLR
LNDELNNLFLRHARYEKNRD-----------PKNASSA---TPSAILGAALGAVEMRD--
-----------PSLIDLSEEPGATGGAA--GHNVSTQLAGLSLAAAGSTATASSQLAQLT
SVTAQSGSSIGGAKS-----PNRATTTAGAPAGSNIPPDVVSDEFDMFA-----------
--------------------QSRNTTGEKEPS--------HRLDALGAPAGANTAALGTR
ES--------EFDEIEQWLGNPDDIDNLEAQLA-------------------AAGAMGGG
DGGAGHGAGTEESLTSK--------------EFEKFLAERAAVAETLPTISSSSTTSSSP
ATTAKD-------------RKKKSDETDGLLAL---------
>gi|118085742|ref|XP_418619.2|	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MRSKRSIRS
C---SADRR---------------------------------------------------
------------------------------EKATSEMNT-AEDWGLILDICDKVGQSR-T
GPKDCLRSIMKRVNH---KDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASE-VSNVL
NKGH------PKVCEKLKALMVEWTD-EF----KNDPQLSLISAMIKNLKEQGV------
-TF---PAIGSQAAEQAKASPALVAKDPGAVANKKEEEDLAKAIE------LSLKEQRQQ
-QTTLSSLYPSTSSLLTNHKH----------EGRKVRAIYDFEAAEDNELTFKAGELITI
LDDS-DPNWWKGETHQGIGLFPSNFVTADLSAEPE----MMKTEKKTVQFSDEVQVETI-
-EPEPEPVYIDEDKMDQLLQ-----------MLQSA-----DPTDDQPDL----------
-----------PELLHLEAMCHQMGPLI------DEKLKDIDRKHSELSELNVKAMEALS
----LYNKLMNEDPM-----YSMYAKLQ-------------NQQYYMQS-S---------
------GVSGSQVYPGQPQGNAYLVAGSAQMG--------HIQGYNLPPEQLSSLSQGTV
TP--------SASSVLPGQPAQTSYTNAMVGSV--------------------AGNTYSN
QASVYSPPPAA-------------------VDVAAYQNAGTNMS-QVPNYNLASTPLPQT
AGSQQAPPQQPQPPPPQQ-PQHSYSQKALL------------
>gi|109506110|ref|XP_001067998.	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPLFAT
N---PFDQDV--------------------------------------------------
------------------------------EKATSELNT-AEDWGLILDICDKVGQSR-T
GPKDCLRSIMRRVNH---KDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASE-VSNVL
NKGH------PKVCEKLKALMVEWTD-EF----KNDPQLSLISAMIKNLKEQGV------
-TF---PAIGSQAAEQAKASPALVAKDPGTVATKKEEEDLAKAIE------LSLKEQRQQ
-AAPLSTLYPSTSSLLTNHQH----------EGRKVRAVYDFEAAEDNELTFKAGEVITV
LDDS-DPNWWKGETHQGMGLFPSNFVTADLTAEPE----MIKTEKKTVQFSDDVQIETIE
PEPEPEPAFIDEDKMDQLLQ-----------MLQST-----DPSDNQPDL----------
-----------PELLHLEAMCHQMGPLI------DEKLEDIDRKHSELSELNVKVMEALS
----LYTKLMNEDPV-----YSVYAKSQ-------------SQQYYVQAS----------
------GVSAPQVYPGPAQSGAYLVAGNAQMT--------HLQSYSLPPEQLASISQGAV
PP--------SATPALPNQQAQASYPNAMVSSV--------------------QGNSYPS
QASIYSPAAAAAAVAVT--------AVPVPADVTIYQNPGPNMS-QVPNYTLTSSTLPHT
GGSQQPPQ-----------PQQAYSQKALL------------
>gi|109113481|ref|XP_001091844.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MEFLLG
N---PFSTPV------GQCL----------------------------------------
------------------------------EKATDGSLQ-SEDWTLNMEICDIINETE-E
GPKDAIRALKKRLNGN--RNYREVMLALTVLETCVKNCGHRFHILVANRDFIDSVLVKII
SPKN---NPPTIVQDKVLALIQAWAD-AF----RSSPDLTGVVHIYEELKRKGV------
-EF---P-----MADLDALSPI---HTPQRSVPEVDPAATMPRSQ------SQQRTSAGS
YSSPPPAPYSAPQAPALSVTG-----PITANSEQIARLRSELDVVRGNTKVM--SEMLTE
MVPG-------QEDSSDLELLQELNRTCR-AMQQR----IVELISR-VS-NEEVTEELLH
VNDDLNNVFLRYERFERYRS-----------GRSVQ-----NASNGVLNEVTE-------
-----------DNLIDLGPGSPAVVSPM-------------------VGNTAPPSSLSSQ
----LAGLDLGTESV-----SGTLSSLQ---------QCNPRDSFDMFAQTRGN------
------SLAEQRKTVTYEDPQAVGGLASALDS--------RKQSSEGIPVAQPSVMD---
-----------------------------------------------------DIEVWL-
-RTDLKGDDLEEGVTSE--------------EFDKFLEERAKAAEMVPDLPSPPMEAPAP
ASNPSG-------------RKKPERSEDALFAL---------
>gi|156544816|ref|XP_001606637.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MSFFGV
NVTNPFTSPV------GQRI----------------------------------------
------------------------------EQATDANLP-SENWALNMEICDIINETE-D
GPRDAIKAIKRRLNQAAGKNYTIVMYTLTVLETCVKNCGKRFHALACSREFVQE-LVKLI
GPKN---EPPIAVQEKVLNLIQTWAD-TF----RNQPHTQGVVQVYQELKTKGI------
-EF---P-----MTDLDAMAPI---ITPERSVPELEAAAAAAAAAAAAAGAVAPTSSSSS
-AAAAVATGGATSRPGSGATCRLPQQPIQLNESQMAKLRSELDVVHGNMRVL--SEMLAA
HSAGLQEKASERAIAEDMELLTELHNTCK-AMQER----VVELIGK-LA-HDELTAELLQ
INDEMNNLFLRYTRFSKNKT-----------MPASALVAQAIGATGSGGMSAAARAKKLE
AG---------DSLIDLSDDEGEAAGAA------ALPVKSLEKR----------------
----VANMDIGDDGK-----SRRKDGEK--------------DEFDAFA-----------
----------------QSRTASFDAAKN-------------RQELRGSDEEEGAITSS--
-----------------------------------------------------EFDRFLA
ERTAAVASEVAAGGNAA----------------------------AAAAAGATGASSTGT
AGATIQ-------------RQIDKEEDKSLFAL---------
>gi|73948986|ref|XP_535174.2|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPLFAT
N---PFDQDV--------------------------------------------------
------------------------------EKATSEMNT-AEDWGHILDICDKVGQSR-T
GPKDCLRSIMRRVNH---KDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASE-VSNVL
NKGH------PKVCEKLKALMVEWTD-EF----KNDPQLSLISAMIKNLKEQGV------
-TF---PAIGSQAADQAKASPALVAKDPGTVANKKEEEDLAKAIE------LSLKEQRQQ
-STTLSTLYPSTSNLLTNHQH----------EGRKVRAIYDFEAAEDNELTFKAGEIITV
LDDS-DPNWWKGETHQGMGLFPSNFVTADLTAEPE----MIKTEKKTVQFSDDVQVETI-
-EPEPEQAFIDEDKMDQLLQ-----------MLQST-----DPSDDQPDL----------
-----------PELLHLEAMCHQMGPLI------DEKLEDIDRKHSELSELNVKVMEALS
----LYTKLMNEDPM-----YSMYAKLQ-------------NQQYYMQSS----------
------GVSGSQVYPGPPQSGTYLVAGSAQMS--------HLQSYSLPPEQLSSLSQGAV
PP--------SVNPALSSQQTQASYPNTMVSSV--------------------QGNTYPT
QASVYSPPPAAAAATAD---------------VTIYQNAGTNMS-QVPNYNLTSSTLPQP
GGSQQPPQ-----------PQQQYSQKALL------------
>gi|149724595|ref|XP_001500222.	Equus caballus
MARFPLPAVIDAAHTLSSQSGAAKRHPRELHERLSIKPPGPRGAEESSNLPVGGAIRAWV
SNSQAAAPGQPGLVGTRRPPGSRAPPRVSPGAGSTASAPVPRGAWQVRARPRSPPRVPLP
RCPTRCPAAARQALSLGRSPGSARAKRRSQGPERVEPGARDRWSQISWARLSAATMAFAK
SHRDPYATSV------GHLI----------------------------------------
------------------------------EKATFAGVQ-TEDWGQFMHICDIINTAH-D
GPKDAVKALKKRISKN--YNHKEIQLTLSLIDMCMQNCGPSFQSLIVKKEFVKDSLVKLL
NPRY---TLPLDVQNRILNFIKTWSQ-GF----PGGVDVSEVKEVYLDLLKKGV------
-QF---P-----PSEAEAERAG-----------------------------LETSQISSN
-PPTPVPSAPALSSVIAPKNS-----TITLVPEQIGKLHSELDMVKMNVRVM--STILME
NIPG-------SENREDMELLQKLYKTGR-EMQER----IMDLLV--VVENEDVTVELIQ
VNEDLNNAILGCERFTRNQQ-----------RILEQNKNQTEDANITSEPSAPS------
-----------CDLLDLSPSPPKPRATL----------GELNSVNAQLSDLN--------
--------FTSSSPA-----VTNNVKPS------------LCPQMDLLA-----------
--------------LENTETSLFAQRTSQNLS--------SSHAYENFPEHSNSVLLQPV
SL--------QTIPATPSNQTLPSLPGNHPAMT-------------------KNDLQLPH
YYEVMEFDPLAPAVTAE-------------------------------------AIYEEI
DGHHQK-------------GAESHSDC---------------
>gi|114629620|ref|XP_001153098.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MPLFAT
N---PFDQDV--------------------------------------------------
------------------------------EKATSEMNT-AEDWGLILDICDKVGQSR-T
GPKDCLRSIMRRVNH---KDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASE-VSNVL
NKGH------PKVCEKLKALMVEWTD-EF----KNDPQLSLISAMIKNLKEQGV------
-TF---PAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIE------LSLKEQRQQ
-STTLSTLYPSTSNLLTNHQH----------EGRKVRAIYDFEAAEDNELTFKAGEIITV
LDDS-DPNWWKGETHQGIGLFPSNFVTADLTAEPE----MIKTEKKTVQFSDDVQVETI-
-EPEPEPAFIDEDKMDQLLQ-----------MLQST-----DPSDDQPDL----------
-----------PELLHLEAMCHQMGPLI------DEKLEDIDRKHSELSELNVKVMEALS
----LYTKLMNEDPM-----YSMYAKLQ-------------NQPYYMQSS----------
------GVSGSQVYAGPPPSGAYLVAGNAQMS--------HLQSYSLPPEQLSSLSQAVV
PP--------SANPALPSQQTQAAYPNTMVSSV--------------------QGNTYPS
QAPVYSPPPAATAAAAT-------------ADVTLYQNAGPNMP-QVPNYNLTSSTLPQP
GGSQQPPQ-----------PQQPYSQKALL------------
>gi|119576090|gb|EAW55686.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MEFLLG
N---PFSTPV------GQCL----------------------------------------
------------------------------EKATDGSLQ-SEDWTLNMEICDIINETE-E
GPKDAIRALKKRLNGN--RNYREVMLALTVLETCVKNCGHRFHILVANRDFIDSVLVKII
SPKN---NPPTIVQDKVLALIQAWAD-AF----RSSPDLTGVVHIYEELKRKGV------
-EF---P-----MADLDALSPI---HTPQRSVPEVDPAATMPRSQ------SQQRTSAGS
YSSPPPAPYSAPQAPALSVTG-----PITANSEQIARLRSELDVVRGNTKVM--SEMLTE
MVPG-------QEDSSDLELLQELNRTCR-AMQQR----IVELISR-VS-NEEVTEELLH
VNDDLNNVFLRYERFERYRS-----------GRSVQ-----NASNGVLNEVTE-------
-----------DNLIDLGPGSPAVVSPM-------------------VGNTAPPSSLSSQ
----LAGLDLGTESV-----SGTLSSLQ---------QCNPRDGFDMFAQTRGN------
------SLAEQRKTVTYEDPQAVGGLASALDN--------RKQSSEGTFLSSAQKRGRGG
ES--------DLEPIDSWLITQGMIPVAQPSVM-------------------DDIEVWL-
-RTDLKGDDLEEGVTSE--------------EFDKFLEERAKAAEMVPDLPSPPMEAPAP
ASNPSG-------------RKKPERSEDALFAL---------
