>gi|147903411|ref|NP_001085558.	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------MTALNWKP---FIYGGLASITAECGT
FPIDLTKTRLQVQGQPNDAKYKEIRYRG--MMHAIVRIWREEGVKALYSGIAPAMLRQAS
YGTIKIGTYQ---SLKRLF----VDCPEDETLVLNAFC---------------------G
VLSGVVSSCIANPTDVLKIRMQAQGN-----------VMQGGMIVNFIN----IYQQE-G
TRGLWKG-----VSLTAQRAAIVVGVELPVYDIT----KKHLILSGLMGDT---------
------------------------------------------------VYTHF----LSS
FTCG---------------------------LAGALASNPVDVVRTRMMN----------
----------------QRSIRDASN----SSY---------KGTLDCLLQTWKNEGFFA-
LYKGFWPNWLR----------------LGPWNIIFFITYE-QLKKLN----L--------
------------------------------------------------------------
-----------------------
>gi|123232765|emb|CAM18796.1|	Mus musculus
MLQTLWHFLSSFLPRAECQDSREGIDHGVR-GTQAPARGD-QMSTF-----LGK-QNGRA
EATEKRPTIL-LVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGGAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMC--IVGGFTQMIREGGAKSLWRGNGINVLKIAP
ESAIKFMAYE---QMKRLV----GSDQETLRIHERLVA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYSGMLDCARR----ILAKE-G
VAAFYKG-----YIPNMLGIIPYAGIDLAVYETLK---NTWLQRYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TISS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASI--E---G--APE---------VTMSSLFKQILRTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKITL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|114626846|ref|XP_001153254.	Pan troglodytes
MLQMLWHFLASFFPRAGCQGSREGDDHEVR-GTPAPARRD-QMASF-----LGK-QDGRA
EATEKRPTIL-LVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGGAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMG--IVGGFTQMIREGGARSLWRGNGINVLKIAP
ESAIKFMAYE---QIKRLV----GSDQETLRIHERLVA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYSGMLDCARR----ILARE-G
VAAFYKG-----YVPNMLGIIPYAGIDLAVYETLK---NAWLQRYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TMSS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASI--E---G--APE---------VTMSSLFKHILRTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKITL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|149601308|ref|XP_001505563.	Ornithorhynchus anatinus
-----MLCLCLYVPVFG-EAQTEFQYFESK-GLPAELKSIFKLSVF-----IPS-QE---
-------------FSTYRQWKQKIVKAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGCIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENVPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGAAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMC--IVGGFTQMIREGGARSLWRGNGINVLKIAP
ESAIKFMAYE---QIKRLV----GTDQETLRIHERLVA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYSGMLDCAKK----IMSKE-G
MAAFYKG-----YIPNMLGIIPYAGIDLAVYETLK---NAWLQRYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TMSS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASI--E---G--APE---------VTMSSLFRQILRTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKITL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|73967957|ref|XP_862482.1|	Canis familiaris
MLQMLWHFLSSLLPRAGCQGSREGKDNEVT-GTLAPARGD-QMSSF-----LGK-QDGKA
EATEKRPTIL-LVVGPAEHFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGGAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMC--IVGGFTQMIREGGAKSLWRGNGINVLKIAP
ESAIKFMAYE---QIKRLV----GSDQETLRIHERLVA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYSGMLDCARK----ILARE-G
MAAFYKG-----YVPNMLGIIPYAGIDLAVYETLK---NAWLQRYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TMSS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASI--E---G--APE---------VTMSSLFRQILRTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKITL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|71000788|ref|XP_755075.1|	Aspergillus fumigatus
------------------------------------------------------------
------------------------------------------------------------
-------MSLDRDQRRRDADVKTSSETKSPELCQLSPPGPV--NAP----PLKSTPVLTK
TKE------------------------------RISDPVIAA---FIAGGVAGAVSRTIV
SPLERLKILLQIQ-----TVGREEYKLS--IWRALVKIGKEEGWRGFMRGNGTNCIRIIP
YSAVQFGSYN---FYKKFA---DPFPDAELSPIRRLLC---------------------G
GAAGITSVTITYPLDIVRTRLSIQSASFAALGHGGTAKKLPGMFTTMVL----IYKNEGG
FVALYRG-----IVPTVAGVAPYVGLNFMTYESV----RKYLTPDGDKNPS---------
------------------------------------------------PWRKL----LAG
AISG---------------------------AVAQTCTYPFDVLRRRFQI----------
----------------NTMS--G--MG--YQY---------KSIWDAVRVIIAEEGLRG-
FFRGIVPNLLK----------------VAPSMASSWLSFE-LTRDFL----VGFSDEK--
------------------------------------------------------------
-----------------------
>gi|72086768|ref|XP_793189.1|	Strongylocentrotus purpuratus
-MKVVEVNAKGGTPPVHPDHELSPEEE----VRYSELFGK-----------LDVDGDGRI
NVDDLQEGLVRMGVHMVPNHAEKFMSKSDQNKDGHLDFSEFVRYVTEHEKQLHIVFKSVD
HNQDGAIDVDEILLSLKKLGVSVSKEEADRLLKSMDKDGTLKVDWN----EWRNYLLLHP
SSDLRDIYAYWRHATFLDIGEDVMVPDEFTEQERQTGMWWRI---LAAGGAAGAVSRTVT
APLDRLKVILQVI-------GSKKPNIG--ILDGFKHMYREGGFKSFWRGNGINVIKIAP
ESAIKFLAYE---RIKRLL----HTEGTELKVYERFVA---------------------G
ALAGVVAQTTIYPMEVLKTRLAIRKT-----------GQYKGILDCAVQ----IYKKE-G
FRCFYRG-----YIPNCLGIIPYAGIDLAVYETVK---NSWIRNH-QDSPV---------
----------------------------------------------PNIAVLL----GCG
TVSS---------------------------TCGQLASYPLALVRTRLQA----------
----------------QTS-----------KT---------ITMGSLFTDIIKTEGVKG-
LYRGITPNFMK----------------VIPAVSIGYVVYE-NTKTLL----GVKAV----
------------------------------------------------------------
-----------------------
>gi|125807071|ref|XP_001360257.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MPDNTPLVQL
LQ-------------------------------------------ALGGGVAGGLTRTLV
QPFDVIKIRFQMQVEPVGKHGYESKYQG--LLHAFRSIYKEEGLRGIWRGHNSGQVLSIT
YAVVQFWSYE---QLRVKA--HKMPFFDDRPLLLYFVC---------------------G
GLAGCLGTVAAQPFDVIRTQVVAADP-----------TSKRSRMSSLRG-VHLVHSTE-G
LRGLSRG-----LVFTLAQIFPLVGANFLIYKYLN---ALVLFIVKKSNPD----HN---
---------------------------------------------IPGP-CLF----VNG
ALAG---------------------------VSSKLLVYPADLMKKRMQL----------
----------------HGFHQDRQTFGRNPIC---------PTAKQCFMTTLKGEGISG-
FYKGVSPTLLK----------------SGLSSAFYFTFYD-YINRYV----IHPMQDREE
QRLK--------------------------------------------------------
-----------------------
>gi|24648424|ref|NP_650891.1|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
--MSRLLEKPNIAMSIKSTGSQLSSTMTTASATLSSDLDDADTSRTQLSPSETSGVVLVP
ATTV-------------------------TPMRQKIDQVVIS---LISGAAAGALAKTVI
APLDRTKINFQIR--------NDVPFSFRASLRYLQNTYANEGVLALWRGNSATMARIVP
YAAIQFTAHE---QWRRIL---HVDKDGTNTKGRRFLA---------------------G
SLAGITSQSLTYPLDLARARMAVTDR----------YTGYRTLRQVFTK----IWVEE-G
PRTLFRG-----YWATVLGVIPYAGTSFFTYETLK---REYYEVVGNNKPN---------
------------------------------------------------TLVSL----AFG
AAAG---------------------------AAGQTASYPLDIVRRRMQT----------
----------------MRVNTAG---G--DRY---------PTILETLVKIYREEGVKNG
FYKGLSMNWIK----------------GPIAVGISFSTYD-LIKAWL----TELANLRRV
EK----------------------------------------------------------
-----------------------
>gi|50307493|ref|XP_453726.1|	Kluyveromyces lactis
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MN----TGIRKDHLRK
GETV---------------------------------SWYNS---VIAGSVSGVFARMAT
APMDTVKIRYQLQ------PVQEDKYKG--IASTVRTIMKEEGLRALWKGNIPATAMYVV
YGAVQFGSYS----WFNNV--WSAKFPRFSQQGQTLTV---------------------G
ALAGMTSSVVSYPLDLLRTRLIANRT-----------SHRTSVAEECRQ----MWLNE-G
VRGFFTG-----ISTAMTTVTLSTAIMFLTYETV----NIVCENHEKEFWS---------
------------------------------------------------RPVSA----SSG
IIAG---------------------------FVSKTMVFPIDTLRRRMQVMNSK------
--------------RTVHFTKFPAVYH-EYRY---------KSSTAIIYKILRQEGVSA-
LYRGLTMGLCK----------------SVPTTAISLFVYE-RTMDLF----DHGQRWGRS
P-----------------------------------------------------------
-----------------------
>gi|157121143|ref|XP_001659846.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MD----RPKEKDVRYT
G---------------------------------------------LAGGITGCTTRSLC
QPFDVIKIRLQLQVEPIHSRSSTSKYRT--IPQTIATVYREEGILAFWKGHNASQVLSMA
QGMAQFTFYE---RFNKVL--REMAIFEGHDRARNFVC---------------------G
AFSGSFATFMVMPLDVIKTRLVSQDP----------DGGYRNAFHAVSS----IYRHE-G
LRGLYRG-----LGPAIMQTAPLTGGQFMFYNLF----GDVIKRLKKVPQE-----D---
---------------------------------------------MLGSTELM----ICG
ALSG---------------------------FCTKLIVYPLDLVKRRLQI----------
----------------QGFSNGRKTYGKHFVC---------KHLLQCMYRVVRKEGMLG-
LYKGLSSSLLK----------------AAITSAIFFTFYDKLLYSFL----KGLPQMGHV
IL----------------------------------------------------------
-----------------------
>gi|149716592|ref|XP_001503130.	Equus caballus
MAAQGYSYYRAVI-----------------------------------------------
------------------------------------------------------------
--FLAMFGGYSLYYFNRKTFSFVMPSVVEEIPLDKDDLGLITSS------QSAAYAISKF
VSGV--------------------------LSDQMSARWLFSSGLLLVGLVNIVFSWSST
VPVFAALWFLNGL-----AQGLGWPPCG----KVLRKWFEPSQFGTWWAILSTSMNLAGG
LGPILATILAQSYSWRSTL-----ALSGALCVVVSFLCLLLIHNEPADVGLRNLDPTPSK
GKKGSLKEESTLRELLLSPYLWVLST---------GYLVVFGVKTCCTDWGQFFLIQEKG
QSALVGS-----SYMSALEVGGLIGSIAAGYLSDRAMAKAGLSIYGNPRHG---------
------------------------------------------------LLLFM----MAG
MTVS---------------------------MYLFRVTVTSDSPKLWILV----------
----------------LGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAVVGLMANVGG
FLAGLPFSTIAKHYSWSTAFWVA--EVICAASTAAFFLLR-NIRTKM----GRVPKKAE-
------------------------------------------------------------
-----------------------
>gi|121698004|ref|XP_001267683.	Aspergillus clavatus
------------------------------------------------------------
------------------------------------------------------------
------MNPNRQQQTQNDMSENSTRDSRRPPLPQLSPSDPV--KTT----SFRSPLFLTK
TRE------------------------------RISDPVIAA---FIAGGVAGAVSRTIV
SPLERLKILLQIQ-----TVGREEYKLS--ISKALLKIGKEEGWRGFLRGNGTNCIRIIP
YSAVQFGSYN---FYKKFA---EPSPNAELSPFRRLIC---------------------G
GAAGITSVTITYPLDIVRTRLSIQSASFAALGQRGSFEKLPGMFTTMVL----IYKNEGG
LVALYRG-----IVPTIAGVAPYVGLNFMTYESA----RKYLTPDGDKTPS---------
------------------------------------------------PWRKL----LAG
AVSG---------------------------AVAQTFTYPFDVLRRRFQI----------
----------------NTMS--G--MG--YQY---------KSVWDAVRVIMAEEGLRG-
FFKGIVPNLMK----------------VAPSMASSWLSFE-LTRDFL----VGLSEEI--
------------------------------------------------------------
-----------------------
>gi|58332328|ref|NP_001011047.1	Xenopus tropicalis
---MLEQVQKFLLSRAACEGP-DPH------TRYAELFHK-----------LDVNKDGKV
DIVELQEGLKAMGMAVGKGAEEKIVAAGDTNKDGHLDFGEFIRYLEEHEKKMKIAFTSLD
KNKDGKIESAEIMNSLKTLGINISLEHAEKILKSMDADGTLTVDWN----EWRDHFLFNP
ADNIQQIIRYWKHSTVLDIGDSLTIPDEFTEEEKKTGQWWKQ---LLAGGMAGAVSRTGT
APLDRLKVMMQVH-------GSKGNAN---IITGLKQMVKEGGIRSLWRGNGVNVIKIAP
ETAMKFWAYE---QYKKLF----TSESGKLGTAERFIA---------------------G
SLAGATAQTSIYPMEVLKTRLAVGKT-----------GQYSGMFDCAKK----IMQRE-G
VRAFYKG-----YIPNILGIIPYAGIDLAIYETLK---TFWLQNYATDSAN---------
----------------------------------------------PGVLVLL----GCG
TASS---------------------------TCGQLASYPLALIRTRMQA----------
----------------QASI--E---G--APQ---------LNMGGLFRKIVAKEGFFG-
LYRGIAPNFLK----------------VLPAVSISYVVYE-KMKIKL----GI-------
------------------------------------------------------------
-----------------------
>gi|109108898|ref|XP_001100288.	Macaca mulatta
MAAQGYGYYRTVI-----------------------------------------------
------------------------------------------------------------
--FSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGLITSS------QSAAYAISKF
VSGV--------------------------LSDQMSARWLFSSGLLLVGLVNIFFSWSST
VPVFAALWFLNGL-----AQGLGWPPCG----KVLRKWFEPSQFGTWWAILSTSMNLAGG
LGPILATVLAQSYSWRSTL-----ALSGALCVVVSFLCLLLIHNEPADVGLRNLDPTPSK
GKKGSLKEESTLQQLLLSPYLWVLST---------GYLVVFGVKTCCTDWGQFFLIQEKG
QSALVGS-----SYMSALEVGGLVGSIAAGYLSDRAMAKAGQSIYGNPRHG---------
------------------------------------------------LLLFM----MAG
MTVT---------------------------MYLFRVTVTSDSPKLWILV----------
----------------LGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGG
FLAGLPFSTIAKHYSWSTAFWVA--EVICAASTAAFFLLR-NIRTKM----GRVSKKAE-
------------------------------------------------------------
-----------------------
>gi|68469593|ref|XP_721048.1|	Candida albicans
------------------------------------------------------------
------------------------------------------------------------
-----------------------MEEYKLQPMAK------------------ESNHLLSD
IKN------------------------------FIKIDSNAS---FIAGGIAGAVSRTVV
SPFERAKILLQLQ-----GPGSQQAYQG--MFPTILKMYREEGWKGLFRGNLLNCIRIFP
YSAVQFATFE---KCKDIMLHYNPRDTQQLNGYERLIA---------------------G
SVGGIVSVAVTYPLDLVRARITVQTASLSKL-NKGKMVRAPKVMETLKD----VYKNEGG
ILGLYRG-----IIPTTLGVAPYVAINFALYEKL----REMMDSSPRDFSN---------
------------------------------------------------PVWKL----SAG
AVSS---------------------------FIGGVLIYPLDLLRKRYQV----------
----------------ASMA--GGELG--FQY---------RSVAHALHSIFTTEGFFG-
AYKGLTANLYK----------------IVPSMAVSWLCYD-TLKDWI----NRW------
------------------------------------------------------------
-----------------------
>gi|118784876|ref|XP_313991.3|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------MD----REKNDTSSNS
G---------------------------------------------IAGGFAGCITRFIC
QPLDVLKIRFQLQVEPLSEQHVTSKYRT--IVQSTRLVYREEGLRAFWKGHNPAQVLSII
YGVAQFSSYE---RFNHLL--RTVDTFERHQSGRNFVC---------------------G
ALSGTFATVITLPLDVVRTRLISQDP----------GRGYRSSVQGLKL----IYRHE-G
VRGLYRG-----LGPSVLQIAPLTGGQFMFYNIFGSMFRQYFNISASETLP---------
------------------------------------------------AIELF----ICG
GMAG---------------------------LCTKLLVYPLDLAKKRLQI----------
----------------QGFAKSRQTYGRHFVC---------DNMFNCLYNIAKQEGPIG-
LYKGLYPALLK----------------ACFMSAFYFAIYDEMLQNVYIYEKKEKKKNRQK
IVEIIVAKAET-------------------------------------------------
-----------------------
>gi|51013669|gb|AAT93128.1|	Saccharomyces cerevisiae
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MFKEEDSLRK
GQNV---------------------------------AAWKT---LLAGAVSGLLARSIT
APMDTIKIRLQLT------PANGLKPFGSQVMEVARSTIKNEGIRSFWKGNIPGSLLYVT
YGSAQFSSYS---LFNRYL-----TPFGLEARLHSLVV---------------------G
AFAGITSSIVSYPFDVLRTRLVANNQ-----------MHSMSITREVRD----IWKLE-G
LPGFFKG-----SIASMTTITLTASIMFGTYETI----RIYCDENEKTTAA---------
----------------------------------------------HKKWELATLNHSAG
TIGG---------------------------VIAKIITFPLETIRRRMQFMNSK------
--------------HLEKFSRHSSVYG-SYKG---------YGFARIGLQILKQEGVSS-
LYRGILVALSK----------------TIPTTFVSFWGYE-TAIHYL----RMY------
------------------------------------------------------------
-----------------------
>gi|21728406|ref|NP_663710.1|	Rattus norvegicus
-----MLCLCLYVPIAG-EAQTEFQYFESK-GLPTELKSIFKLSVF-----IPS-QE---
-------------FSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGGAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMC--IIGGFTQMIREGGAKSLWRGNGINVLKIAP
ESAIKFMAYE---QMKRLV----GSDQETLRIHERLVA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYSGMLDCAKR----ILAKE-G
VAAFYKG-----YIPNMLGIIPYAGIDLAVYETLK---NTWLQRYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TISS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASI--E---G--APE---------VTMSSLFKQILRTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKITL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|126297618|ref|XP_001362852.	Monodelphis domestica
MVSSV-LCRCVASPPAPGASSTQSPSGDPCGGAVCGGPDH-RLRLWSLFQELDVNRDGGL
CVNDLAVGLRRLGLHRTEVELRKIVKAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENVPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGGAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMC--IVGGFTQMIREGGAKSLWRGNGINVIKIAP
ESAIKFMAYE---QIKRLV----GSDQETLRIHERLVA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYLGMLDCAKK----ILSKE-G
MTAFYKG-----YVPNMLGIIPYAGIDLAVYETLK---NTWLQRYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TISS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASI--E---G--APE---------VTMSSLFKQILRTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKITL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|150865838|ref|XP_001385219.	Pichia stipitis
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------ME----SRKREDHLRK
GSEV---------------------------------SPYES---LLAGSISGAVARAVT
APLDTIKIRLQLQ------RSAFRSRVS--VTTVVKDLLKNEGAIALWKGNVPAEILYVL
YGAAQFTTYSSISRWLSHL--SDTSGFNLPSSAHSLVS---------------------G
TGAGVVSTLVTYPFDLLRTRLAANSE-----------KKLLSMSGTARE----IISSE-G
FTGLFAG-----IKPAMLSISTTTGLMFWSYELV----RETLGDRDI-------------
------------------------------------------------PFKEG----ICG
FIAG---------------------------ATSKGITFPLDTIRKRTQM----------
----------------YKILYNS------AKR---------VGAFRLLADIVANEGVLG-
LYKGFGISVLK----------------TSPTSAVSLFVYE-YSLAAI----QRINRKTLD
------------------------------------------------------------
-----------------------
>gi|91088017|ref|XP_974079.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
-----------------------------MALKT----------------ENKKFEFVAK
N--------------------------------------------LLAGGIAGMVSKTTV
APLDRIKILLQAH---------NKHHECHGVFSGLRHIIKTESPWAMYKGNGAQMLRIFP
YAATQFTSFE---IYKRYL----DGVFGSTSHIDKFIA---------------------G
AGAGLTAVTLTYPLDTIRARLAFQIS---------GEHVYTGIAHAATT----IFKEEGG
TRALYRG-----FVPTLMGMVPYAGLSFYCFEYLKYGCMKYLPKLTCNPCEKNTGGL---
---------------------------------------------VLAMPAKL----ICG
GLAG---------------------------AVAQSVSYPLDVTRRRMQL----------
----------------ALMNPHT---E--KFA---------KGMLNTLRLIYNENGVLKG
WYRGMSINYLR----------------AIPMVAVSFTTYE-TCKQVLNLDTGLQVK----
------------------------------------------------------------
-----------------------
>gi|47086085|ref|NP_998422.1|	Danio rerio
-----MLCLCLYVPVHN-SDQIEVEYFESN-GLPSELKSLKSLSVL-----LPS-QE---
-------------FSTYRRWRKKSLKTEEKEHDGQLDFEEFVHYLQDHEKDLKLVFKSMD
RKIAGQVNANDIVNSLRDLGVHISLKQAEKVLKSMDKNGTMTIDWN----EWKKYPTLQP
AENIPEIILYWKHSTIFDVGESLMVPDEFTVEEHLTGMWWRH---LVSGGGAGAVSRTCT
APLDRLKVLMQVH-------GCQGKSMC--LMSGLTQMIKEGGVRSLWRGNGINVIKIAP
ETALKFMAYE---QIKRVM----GSSQETLGISERFVA---------------------G
SLAGVIAQSTIYPMEVLKTRLALRKT-----------GQYKGISDCAKH----ILKTE-G
MSAFYKG-----YVPNMLGIIPYAGIDLAVYETLK---NTWLQRYGTENAD---------
----------------------------------------------PGVFVLL----ACG
TVSS---------------------------TCGQLASYPLALIRTRMQA----------
----------------QASV--E---G--SSQ---------VSMTGLFKQIMKTEGPTG-
LYRGLTPNFLK----------------VIPAVSISYVVYE-HIKSTL----GVRSR----
------------------------------------------------------------
-----------------------
>gi|111120296|gb|ABH06333.1|	Bos taurus
-----MLCLCLYVPLIG-EAQTEFQYFESK-GLPAELKSIFKLSVF-----IPS-QE---
-------------FSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGGAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMC--IVGGFTQMIREGGARSLWRGNGINVLKIAP
ESAIKFMAYE---QIKRLI----GSDQETLRIHERLVA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYSGMLDCARK----ILARE-G
MAAFYKG-----YVPNMLGIIPYAGIDLAVYETLK---NAWLQRYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TMSS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASM--E---G--APE---------VTMSSLFKQILRTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKITL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|83775254|dbj|BAE65377.1|	Aspergillus oryzae
------------------------------------------------------------
------------------------------------------------------------
-------MSLDRQESVRHDESKTSRDNTLAKLTQLPPSSASIKEAS----SGNSSKFVGK
LKG------------------------------RIAEPVVAA---FVAGGVAGAVSRTIV
SPLERLKILLQIQ-----SVGREEYRLS--IWKALVKIGKEEGWRGFMRGNGTNCIRIIP
YSAVQFGSYN---FYKRFA---EPTPDAELSPVRRLIC---------------------G
GAAGITSVTITYPLDIVRTRLSIQSASFAALGQRDGSGKLPGMFGTMVL----MYKTEGG
ILALYRG-----IIPTVAGVAPYVGLNFMTYESV----RKYLTPDGDKTPS---------
------------------------------------------------SLRKL----LAG
AISG---------------------------AVAQTCTYPFDVLRRRFQI----------
----------------NTMS--G--MG--YQY---------ASVWDAVKVIVAEEGTRG-
LFKGIVPNLLK----------------VAPSMASSWLSFE-LTRDFL----VQLNDK---
------------------------------------------------------------
-----------------------
>gi|56699407|ref|NP_001006643.1	Homo sapiens
MLQMLWHFLASFFPRAGCHGSREGDDREVR-GTPAPAWRD-QMASF-----LGK-QDGRA
EATEKRPTIL-LVVGPAEQFPKKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGGAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMG--IVGGFTQMIREGGARSLWRGNGINVLKIAP
ESAIKFMAYE---QIKRLV----GSDQETLRIHERLVA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYSGMLDCARR----ILARE-G
VAAFYKG-----YVPNMLGIIPYAGIDLAVYETLK---NAWLQHYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TMSS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASI--E---G--APE---------VTMSSLFKHILRTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKITL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|156537450|ref|XP_001607039.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
--MSGHVE--------NSLGTAIQLPIMAPITKVHSLSPTSLKNDD----NKADASATYQ
EASI-----------------------------TNSQRVFTS---LAAGAIAGGVAKTAI
APLDRTKIKFQIS---------KQPFTARAAIDSLINDYKRDGLVSLWRGNSATMVRIIP
YAAIQFTAFE---QWKRIL----KVEEEHDHKTRRFLA---------------------G
ALAGTTSQSMTYPLDLARAQMAVSQK-----------DEIKNLRHVFIR----IYEKE-G
IASFYRG-----FTPTILGVIPYAGVSFFFYDTL----KNTFSVYTVHNPG---------
----------------------------------------------LSAMSGL----VSG
AVAG---------------------------MMGQATSYPLDIVRRRMQT----------
----------------STLN--N---N--LNT---------LGVLQMTKKIYAEDGIRS-
FYKGLSMNWVK----------------GPIAVGISFATYD-LVKDTL----RKILC----
------------------------------------------------------------
-----------------------
>gi|110750141|ref|XP_396993.3|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
--------------------MSVLSNSTKQVLQNTSSLSMEIQDDNTIMCNKKKQEKNIG
SNGI-----------------------------SNAQRVWTS---LLSGAIAGALAKTTI
APLDRTKINFQIS---------NQPFSAKAAIKFLIKTFRTEGLLSLWRGNSATMVRIVP
YSAVQFTAHE---QWKRIL---GVNGSEREKPGLNFLA---------------------G
SLAGITSQGTTYPLDLMRARMAVTQK-----------TKYKTLRQIFVR----IYMEE-G
IAAYYRG-----FTATLLGVIPYAGCSFFTYDLL----RNLLTVYTVAIPG---------
------------------------------------------------FSTSL----ICG
AIAG---------------------------MVAQTSSYPLDIIRRRMQT----------
----------------SAMH------G--QHY---------HTIRSTIIKIYKEEGIMA-
FYKGLSMNWIK----------------GPIAVGISFATHD-TIRDTL----RKIIICQNT
SLKT--------------------------------------------------------
-----------------------
>gi|90081982|dbj|BAE90272.1|	Macaca fascicularis
------------------------------------------------------------
------------------------------------------------------------
--------------------MGIFPGIILIFLRV----------------KFATAAVIVS
GHQK-----------------------STTVSHEMSGLNWKP---FVYGGLASIVAEFGT
FPVDLTKTRLQVQGQSIDARFKEIKYRG--MFHALFRICREEGVLALYSGIAPALLRQAS
YGTIKIGIYQ---SLKRLF----VERLEDETLLINMIC---------------------G
VVSGVISSTIANPTDVLKIRMQAQGS-----------LFQGSMIGSFID----IYQQE-G
TRGLWRG-----VVPTAQRAAIVVGVELPVYDIT----KKHLILSGMMGDT---------
------------------------------------------------ILTHF----VSS
FTCG---------------------------LAGALASNPVDVVRTRMMN----------
----------------QRAI-----VGHVDLY---------KGTVDGILKMWKHEGFFA-
LYKGFWPNWLR----------------LGPWNIIFFITYE-QLKRLQ----I--------
------------------------------------------------------------
-----------------------
>gi|45184859|ref|NP_982577.1|	Ashbya gossypii
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MAASSGSP----QLATEDHLRK
GEAV---------------------------------SGLHA---VVAGSVSGLVARSVT
APMDTVKIRRQLQ------LASEHKYHG--ILHTFRTVAREEGVRALWKGNVPASAMYVL
YGSLQFGTYA----WLNTA----AASAGLPPQAHSLAV---------------------G
ALAGLVSSLLTYPLDLLRTRLVANRS-----------AHFFSLRRQARV----IWDTE-G
PAGFFRG-----GAWAIAATTLTTGLIFGIYETC----TIAADTYGL-------------
------------------------------------------------PWLAA----AAS
PTAG---------------------------LVSKAAVFPLDTVRRRLQIVDAK------
--------------HIPFFTRDPGAYS-ALRG---------TRFLGLAVHMVRAEGIAS-
LYKGLTMALCK----------------STPTTVITLWVYQ-RCLRLL----EPTRAPQLP
A-----------------------------------------------------------
-----------------------
>gi|47211393|emb|CAF90629.1|	Tetraodon nigroviridis
---MFQLGARLFFTDCRCAASRDGP------QSYEELFAK-----------LDANKDGKV
DVAELRAGLAAMGIKSGKGAAQKIISSGDKDQDEGLDFAEFSKYLKEHEKKLKLTFKSLD
KNNDGRIDHLQIRHSLADLGLDITQEEAEKILQSIDVDGTMTVDWN----EWREHFLFNP
ATNLQEIIRYWKHSTVLDIGESLAIPDEFTEEEKTSGLWWKQ---LSAGAMAGAVSRTGT
APLDRMKVFMQVH-------ATKSNKIS--LVGGFKQMLKEGGVTSLWRGNGINVLKIAP
ETAIKFMAYE---QFKKLL----ASEPGSVKTHERFMA---------------------G
SLAGATAQTAIYPMEVLKTRLTLRKT-----------GQYSGMFDCAKK----ILKKE-G
VKAFYKG-----YIPNILGIIPYAGIDLAIYESLK---NLWLSKYAKDTAN---------
----------------------------------------------PGILVLL----GCG
TISS---------------------------SCGQVASYPLALIRTRMQA----------
----------------QASV--E---G--SKQ---------TSMSQIAKMILEKEGFFG-
LYRGILPNFMK----------------VIPAVSISYVVYE-NMRYSL----GIQK-----
------------------------------------------------------------
-----------------------
>gi|118099247|ref|XP_001233165.	Gallus gallus
MLQSLWRFLSSFLPRAACQGPADGKDDEARNATPLPGPGE-KGPKV-----LGKPQDRGT
DPTERRPTIL-LVVGPAEHFPKKIVKAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLD
KKNDGRIDAQEIVQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWN----EWRDYHLLHP
VENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRH---LVAGGGAGAVSRTCT
APLDRLKVLMQVH-------ASRSNNMC--IIGGFTQMIREGGTRSLWRGNGINVLKIAP
ESAIKFMAYE---QIKRFI----GTDQEMLRIHERLLA---------------------G
SLAGAIAQSSIYPMEVLKTRMALRKT-----------GQYSGMLDCAKN----ILSKE-G
MAAFYKG-----YIPNMLGIIPYAGIDLAVYETLK---NAWLQRYAVNSAD---------
----------------------------------------------PGVFVLL----ACG
TISS---------------------------TCGQLASYPLALVRTRMQA----------
----------------QASV--E---G--APE---------VTMRGLFKHILKTEGAFG-
LYRGLAPNFMK----------------VIPAVSISYVVYE-NLKMTL----GVQSR----
------------------------------------------------------------
-----------------------
>gi|6321533|ref|NP_011610.1|	Saccharomyces cerevisiae
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MFKEEDSLRK
GQNV---------------------------------AAWKT---LLAGAVSGLLARSIT
APMDTIKIRLQLT------PANGLKPFGSQVMEVARSMIKNEGIRSFWKGNIPGSLLYVT
YGSAQFSSYS---LFNRYL-----TPFGLEARLHSLVV---------------------G
AFAGITSSIVSYPFDVLRTRLVANNQ-----------MHSMSITREVRD----IWKLE-G
LPGFFKG-----SIASMTTITLTASIMFGTYETI----RIYCDENEKTTAA---------
----------------------------------------------HKKWELATLNHSAG
TIGG---------------------------VIAKIITFPLETIRRRMQFMNSK------
--------------HLEKFSRHSSVYG-SYKG---------YGFARIGLQILKQEGVSS-
LYRGILVALSK----------------TIPTTFVSFWGYE-TAIHYL----RMY------
------------------------------------------------------------
-----------------------
