>gi|86212163|gb|ABC87741.1|	Tetraodon nigroviridis
------------------------------------------------------------
---------------------------------------MPQSKSFGHEDQGKRSS-FKG
RMTQNCFCPPPLPQQFLQTQRPSPLGFG---------------------PAGRSFVLAKM
TAMPQRY--SHQRRRTSTAAAARRM--------EKRRREQGKNNSLTSDHNSYRSRKLSM
LSRAADNTHWSKPQ---PSTAENTHNLVHRTASVRENKRSIRRSFSVK------------
-PVQRSFSSAHLMNSCSNVQAFI-----IGTVVLMKGHGKGLGFSIVG-GQDSMYG-PMG
IYVKTIFPGGAAAADGRLQEGDEILEVNGESLHGLTHDEALHKFKQVRKGLLTLVVRTSL
RL-GTLCGPTQLCRSRSLCSTADMARDNTDLENYLNNNCSNTLSLSGPPTNRDRIIMEMV
LQKEAGVGLGIGLCCVPSGEGCPRIYIHTFSPGSVAHMDGRLRYGDEIIEINDTVVYNMA
LNDVYTVLSQCTPGPVHIIISRHP-NPKVSEEQLNDAIAQAVENSKLRKDKNQWSANGMQ
RFYT--HSRHKCETCVDRSFSQQTIHHGQRIMTRSCSDSTNSHHHHNRCVRTHNLQHYHH
SPSARVHSLDVPKSETWPENRLSVPVYPDEEYNI-----PYSCPSASATCQRNVNFTFSK
FSCNGSPGPHQISRTDMDLSTEDGYTGDSSGSSRESPIRHRRLAP---------------
----SSRGVCKQGERLKEDSPESKDSAHPESAVGAEIPTGDSLVVVCSQPKRGALRRQVC
VDQHQDPWVRHSDTSPEELPKAQHCPVGSPRPENICSKPPIMTESEK---------LPIL
DDSVEPPEPLSDVTLAEFPSGAKKGPPVAPKPPWFRQSLKKIQDERERKK--TDKPAAQK
PHVGFSRSFGGRSGSSAANLSIKQKIHSFETFSTPAAPEMVENK---KPTSVSSFCPP--
VESKSHS---GSINNKKDEVPEEIQANPPPSASTINPSTSEGQPQHPQEQPVSNQEPRDL
VVADLDSGSNDAVSSPDHDERNTSPSEQEPETEGSAVSPSATSLRP-----SEGLANSPQ
VDIEMDGALNGNQLQKDLDGENLEKILTLSNQVSQALMHSL------------------A
MQPRHDSKRPPSPEDTSCVDFTSES--APTSFSVSLAALREC---ITEQGELELED----
--KTRSASIQAAVSAIPSDRMQSVVQEMQTLEDDTLKQLEDIHLVVLHKDEGIGLGFSIA
GGSDLENKVLTVHK---------VFSSGLAAQEGTI----------EKGDEVLSINGQIL
RGLTHAEATAALRQTRNLMLAVVVVGKQAEAEGAKEGRSMDE-------SGVTVE-----
--VQGGPITVKIIKGAAGVGFTLEGGKGSIH-----GDRPLVINRIFTD-----DDALKM
GDVLLQVQDVSVQEMTRFEAWNLVKSL-----------PEGP--VTVVIARK-------T
GAAE-----------------------
>gi|109462172|ref|XP_001062855.	Rattus norvegicus
MGLAPWGQKCICKGQVQQLGCGCPVLPAGGGHHQYALWHIHRRTPLLGCQGTAPPPCCSW
HLLPGQANRTHAAAAKPSSSTTHRPRPGEQERKKRGLTSSLRMEPHSHSGKSRKSTKFRS
ISRSLILCNAKTSDDSSSPDEKYPDPFETSLCQDKEGFFHSSMQLADTSEAGLSNI-PDL
ALASEAA--QLQAAGSDRGKHCRKMFFLKESSTTSSKEKAGKSEAQSSNFLFPKACHQRT
RSNSTSVNPYSAREMDFPMTKKSAAPTDRQPYSLCSNRKSLSQQLDYP---VSGT----A
RPT-RSLSTAQLGQLSGGLQASV-----ISNIVLMKGQAKGLGFSIVG-GKDSIYG-PIG
IYVKSIFAGGAAAADGRLQEGDEILELNGESIAGLTHQDALQKFKQAKKGLLTLTVRTRL
TTPPSLCSHLSPPLCRSLSSSTCGAQDSSPFSLESP---ASPASTAKPNY---RIMVEVS
LKKEAGVGLGIGLCSIPYFQCISGVFIHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCMT
LNEVYTILSHCDPGPVPIIVSRHP-DPQVSEQQLKEAVAQAVEGVKFGKERHQWSLEGVK
RLESSWHGRPTLEKEREKH-SAPPHRRAQKIMVRSSSDSSYMSGSPGGSPCSAGAELQPS
EGEGSTHSPSLPPGEEQEPCPGVPSRPHQESPPLSESLERDSHPPLKLKNSFEILV-RKP
TSTKPKPPPRKYFKNDSEPQKKLEEKEKVTDPSGHTLPTCSQETRELLP----LLLQEDT
AGRTLCTAACCPGPAA---STQTSSSTEGEP-RRSASPETPASPGKHPLLKRQARMDYSF
DSTTEDPWVRISDCI-----KNLFSPIMSENHSHMPLQPNASLGEEDGTQGHPEGGLSKM
DTANGAPRIFKSAD----GSTVKKGPPVAPKPAWFRQSLKGLRNRVPETRRAPEVASAIQ
TTPVSRDASGPQSQAS--SSSIRQRISSFENFGSSQLPDRGVQRLSLQPTSGETTRLPGK
QDEGRFS---GLPAQGTKVTAKHRQTEVEPPSTTFPNSSEVGDPDMSESPPPGQRPNPKA
LS---------------PDPLLRLLTTQTEDTQGPGFKMPSQRARS-----FP-LTRTQS
YETKL-------------LDEKSSKLYSISSQLSSAVMKSLLCLPSSASCGQI------T
CIPKERVSPKSPCNNSAAAEGFGEAVASDTGFSLNLSELREYSEGLTEPGETEDRN----
--HCSSQAGQSVISLLSAEELKKLIEEVRVLDEATLKQLDSIHVTVLHKEEGAGLGFSLA
GGADLENKVITVHR---------VFPNGLASQEGTI----------QKGNEVLSINGKSL
KGATHNDALAILRQARDPRQAVIVTRKAIVEAAHDLNSSTDSAASASVASGISVES----
--VEATVCTVTLEKTSAGLGFSLEGGKGSLH-----GDKPLTINRIFKG--TEQGDAVQP
GDEILQLAGTAVQGLTRFEAWNVIKAL-----------PDGP--VTVVIRRNGLEGKQTT
ASADL----------------------
>gi|60360480|dbj|BAD90484.1|	Mus musculus
-----------------------RAVPAGSG-----------------------------
---------THAVAAKSSSSVTHRPRPGEQERKKRGLTSSLRMEPHGHSGKSRKSTKFRS
ISRSLILCNAKTSDDGSSPDEKYPDPFETSLCQGKEGFFHSSMQLADTFEAGLSNI-PDL
ALASDSA--QLAAAGSDRGKHCRKMFFMKESSSTSSKEKSGKPEAQSSSFLFPKACHQRT
RSNSTSVNPYSAGEIDFPMTKKSAAPTDRQPYSLCSNRKSLSQQLDYP---ILGT----A
RPT-RSLSTAQLGQLSGGLQASV-----ISNIVLMKGQAKGLGFSIVG-GKDSIYG-PIG
IYVKSIFAGGAAAADGRLQEGDESLELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRL
TTPPSLCSHLSPPLCRSLSSSTCGAQDSSPFSLESP---ASPASTAKPNY---RIMVEVS
LKKEAGVGLGIGLCSIPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCLT
LNEVYTILSHCDPGPVPIIVSRHP-DPQVSEQQLKEAVAQAVEGVKFGKDRHQWSLEGVK
RLESSWHGRPTLEKEREKH-SAPPHRRAQKIMVRSSSDSSYMSGSPGGSPCSAGAEPQPS
EREGSTHSPSLSPGEEQEPCPGVPSRPQQESPPLPESLERESHPPLRLKKSFEILV-RKP
TSSKPKPPPRKYFKNDSEPQKKLEEKEKVTDPSGHTLPTCSQETRELLP----LLLQEDT
AGRAPCTAACCPGPAA---STQTSSSTEGES-RRSASPETPASPGKHPLLKRQARMDYSF
DITAEDPWVRISDCI-----KNLFSPIMSENHSHTPLQPNTSLGEEDGTQGCPEGGLSKM
DAANGAPRVYKSAD----GSTVKKGPPVAPKPAWFRQSLKGLRNRAPDPRRPPEVASAIQ
PTPVSRDPPGPQPQA---SSSIRQRISSFENFGSSQLPDRGVQRLSLQPSSGETTKFPGK
QDGGRFS---GLLGQGATVTAKHRQTEVESMSTTFPNSSEVRDPGLPESPPPGQRPSTKA
LS---------------PDPLLRLLTTQSEDTQGPGLKMPSQRARS-----FP-LTRTQS
CETKL-------------LDEKASKLYSISSQLSSAVMKSLLCLPSSVSCGQI------T
CIPKERVSPKSPCNNSSAAEGFGEAMASDTGFSLNLSELREYSEGLTEPGETEDRN----
--HCSSQAGQSVISLLSAEELEKLIEEVRVLDEATLKQLDSIHVTILHKEEGAGLGFSLA
GGADLENKVITVHR---------VFPNGLASQEGTI----------QKGNEVLSINGKSL
KGATHNDALAILRQARDPRQAVIVTRRTTVEATHDLNSSTDSAASASAASDISVES----
--KEATVCTVTLEKTSAGLGFSLEGGKGSLH-----GDKPLTINRIFKG--TEQGEMVQP
GDEILQLAGTAVQGLTRFEAWNVIKAL-----------PDGP--VTIVIRRTSLQCKQTT
ASADS----------------------
>gi|125813106|ref|XP_691830.2|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
-----MRCVDRSTSQLTCRRTQKP----------------------------------MI
RSCSEGA--YSQRCCIPNSTTAQSF--------------------LHTDHVSLTTNSETS
LNNTLSQSSFTDDDYNIP--------------------------YKCPV-----------
------------------------------------------NFNGKQ-TFDVNAS----
-------SGLVNQPRKYCRQQQEVSSQEALNVSSGSSRDSPVKEEDLM------------
---------LSQSNCQEVVEHAELGT-------------KASACISEPKS----------
---------------------------------DSTHRGDRLHK----------------
-------------------------DPECSSQ-----VCGSSKRVGLRRQAH--------
-----------LEVSTDQP-LDPWVKLTDSPENQSYCSKTMSDHNGDSEVNGTASETTES
KSEQATSV------KKGPPVAPKSARA------------RQSMKSIKSGKPITEAF-RNQ
QDNRSHETGRTFGISSRAA-----------------------------------------
----SSGGNLSIRQKISSFETFSSPDGSERPSWRMAPT---ASVPPTEKTTKTSSADYSN
ADRT---RVNTSN-----LRNNDYC------QSTPPISATTLLSEEHSTSLI-------L
ESHPGVEKQSTSHD-------------------------------SETCKSIPVEEPTVD
P-----------------TEEITTAVETEQELVSSAKS----------------------
----------SVDTEHKPVSSSETEQEPVSSTKSSVETEPVTSAETKQEPVSSEKDLPSV
TH--------------VPRRSSSSKEAPGEKAEDAGTHAVSLRTRS--------LPLSPS
SDGPI---------SSGLEGESLGIILSFSNQVSSALMRSMQSLPQSPCIRLGNPWSAPP
GSPLHNPIEEDSAAENPHASTALEN--NEKGFSVSLAELRERTIERGEECKTDDWKPEQA
LTSASAACAQSMLSVLPQPEIQRMIQEVKDLDEDTLRQLEDIHVVILHKEEGAGLGFSIA
GGIDLENKATTVHR---------VFPSGLAAQEGTI----------EKGDEVLSINGQTL
KNVTHSDATAILRQSRTLKQAVVVVSKNKDAEGKSANA---NESSCSGGAESSIAGD---
--DGGEVVTFELEKNAGGVGFSLEGGKGSIS-----GDRPLAVNRIFTGSDAEQKG-LKS
GDEVLQIQDSSLQGLTRFEAWTLIKNL-----------NDGR--FTLIVKRRRCEQS---
---------------------------
>gi|36953836|gb|AAQ86961.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------MESHSRAGKSRKSAKFRS
ISRSLMLCNAKTSDDGSSPDEKYPDPFEISLAQGKEGIFHSSVQLADTSEAGPSSV-PDL
ALASEAA--QLQAAGNDRGKTCRRIFFMKESSTASSREKPGKLEAQSSNFLFPKACHQRA
RSNSTSVNPYCTREIDFPMTKKSAAPTDRQPYSLCSNRKSLSQQLDCPAGKAAGT----S
RPT-RSLSTAQLVQPSGGLQASV-----ISNIVLMKGQAKGLGFSIVG-GKDSIYG-PIG
IYVKTIFAGGAAAADGRLQEGDEILELNGGSMAGLTHQDALQKFKQAKKGLLTLTVRTRL
TAPPSLCSHLSPPLCRSLSSSTCITKDSSSFALESP---SAPISTAKPNY---RIMVEVS
LQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEISDSPVHCLT
LNEVYTILSHCDPGPVPIIVSRHP-DPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVK
RLESSWHGRPTLEKEREKN-SAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSS
DVDISTHSPSLPLAREPVVLSIASSRLPQESPPLPES--RDSHPPLRLKKSFEILV-RKP
MSSKPKPPPRKYFKSDSDPQKSLEERENSSCSSGHTPPTCGQEARELLP---LLLPQEDT
AGRSPSASAGCPGPGI---GPQTKSSTEGEPGWRRASPVTQTSPIKHPLLKRQARMDYSF
DTTAEDPWVRISDCI-----KNLFSPIMSENHGHMPLQPNASLNEEEGTQGHPDGTPPKL
DTANGTPKVYKSAD----SSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQ
PAPASREHLGSHIRASSSSSSIRQRISSFETFGSSQLPDKGAQRLSLQPSSGEAAKPLGK
HEEGRFS---GLLGRGAAPTLVPQQPEQV-LSSGSPAASEARDPGVSESPPPGRQPNQKT
LP-------------PGPDPLLRLLSTQAEESQGPVLKMPSQRARS-----FP-LTRSQS
CETKL-------------LDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQT------P
CIPKEGASPTSSSNEDSAANGSAETSALDTGFSLNLSELREYTEGLTEAKEDDDGD----
--HSSLQSGQSVISLLSSEELKKLIEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLA
GGADLENKVITVHR---------VFPNGLASQEGTI----------QKGNEVLSINGKSL
KGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVEST---
--AEATVCTVTLEKMSAGLGFSLEGGKGSLH-----GDKPLTINRIFKGAASEQSETVQP
GDEILQLGGTAMQGLTRFEAWNIIKAL-----------PDGP--VTIVIRRKSLQSKETT
AAGDS----------------------
>gi|109100732|ref|XP_001096378.	Macaca mulatta
------------------------------------------------------------
-------------------------------------------MDVALWDTGEPGAGNYG
RLKLYFESLDNSCDEEIKEKQQSKSRIGINKSSGTQSG-------------SQRMIAMLI
AVFEEQE--PLHKIESPSGNPAERQ-----------------SPDAFETEVASQLAAFKP
IGGEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPGASHPGGQSLKPVVSDSTQ--NLE
EREVMNGVQTELTSPKTKDTLSD-----MTRTVEISGEGGPLGIHVVP-FFSSLSGRILG
LFIRGVEENSRSKREGLFHENECIVKINSVDLVDKTFAQAQDVFRQAMKS----------
---PSVLLHVLPPQNREQYEKSVIG----PLNIFGNND-GVLKTKAPPPV----------
-------------------HGKSGLKAANLSGAESPETDASTCLQQNK------------
-------------------------SPRVPRLGGKPSSPSLSPLMGFGSKKNAKKIK--I
DLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGR
TQEELVAMLRST--KQGETASLVIARQEGHFLPRELKGEPD-CCALSLETSEQLTF-EIP
L-----------------------------------------------------------
----NDSGSAGLGVSL---KGNKSRETGTDLGIFIKSI-------------------IHG
GAAFKDGRLRMNDQL---IAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRP
ERPMEDPAECGAFS----------------KPCF------------ENCQ--NAVTTSRR
NDNSTLHPLGTYSPQDKQKDLLLPNDGWTESEVPPSPTPHSALELGLEDYSHSSGVDSAV
YFPDQHI---NFRSVTPARQPESINLKASKSMDLVPDESKVHSLAGHKSESPSKDFGPTL
GL----------------KKSSSLESLQTAVAEVRKNDLPFHRPRP-----H--MVRGRG
CNESF-----RAAIDKSYDGPEEIEADGLSDKSSHSGQGALNCESAPQGNSELEDMEN-K
ARKVKKTKEKVKKKEKGKLKVKEKKRKEENEDPERKIKKKGFSAMLRFGKKKEDKG----
--GKAEQKGALKHGGLREEELEKMKEERERIGAKHQELREKQARGLLDYATGAIGSVYDM
DDDEMDPNYARVNHFREPCTSANVFRSPSPPRAGPFGYPRDGRPLSPERDHLEGLYAKVN
KPYHPLAPADSGRPTGGSTDRIQKLRKEYYQARREGFPLYEDSEGRARPSDYDLLWVPGK
G-PDGNAHNLRFEGMERQYASLPRGGPADAVDYLPAAPRGLYKERELPYYPGAHPMHPPK
GS-YPRPTELRVADLRYPQHYPPPPASQHKGPFRQDVPPSPPQHQRMPAYQETGRPAPRG
GSPDQYPYRTQDSRQKNPMTAAV----
>gi|73951275|ref|XP_860788.1|	Canis familiaris
------------------------------------------------------------
------------------------------------------MDPHSRSGKSRKSTKLRS
ISRSLMLCNAKTSDDGSSPDEKYPDPFETSLGQSKEGIFHSSVQLADTSEAGRGSV-PDL
ALASEAT-------GSDRGKSSRRIFFMKEAATTSSREKSGKADTQSSHFLLPKARHQRT
RSNSTSVNPYCMGEIDFPMIKKSAACTDRQPYSLCSSRKSLSQQLDCPAGRVAGT----S
RPT-RSLSTAQLAQPSGGLQASV-----ISNIVLMKGQAKGLGFSIVG-GRDSIYG-PIG
IYVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRL
TTPPSLSSHLSPPLCRSLSSSTCAAKDSSPLGLESPATLATPASTAKPNY---RVMVEVS
LQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCMT
LNEVYAILSHCSPGPVPIIVSRHP-DPQVSELQLIEAVAQAVENVKFGKERHQWSLEGVK
RLESSWHGRPTLEKEREKN-SAPPHRRAQKVMIRSSSDSSYMSGSPGGSP-ISGCEQLTS
DPEVPTHSPSLSLGQEPGALPVALSRPPQESPPLPGM--PDSHPPLRLKKSFEILV-RKP
TTSKPKPPPRKYFKSDSDPQKSPEEREDPLCPSGHTLPTCGQEARERLPPPPLPLPQEDT
AGRAPHALACCPGPTV---DPHTAPSSEPEPGRRRGSPGTQTSPVKHPLLKRQARMDYSL
DITAEDPWVRISDCI-----KNLFSPIMSENHSHVSLPPSVGLGGEDGPRGHPDGTPPKL
DATSGASKAYKSAD----SSSVKKGPPVAPKPAWFRQSLKSLRTRAAEPRRLPDTASSSK
PAPASRERPGAPTRAF--SSSIKQRISSFETFGSAQLPNRGAQRLSLQASMGEAAQSPGE
QDGGQVP---GLSGRGPPHTVEQQQPEPEPLPRGTLTSSKTSELGVSGSPLPGRQSSRET
LL-------------PDPDPLSRLLSTHTEEAQGPVVKMPSQRARS-----FP-LSRTQS
WEMKP-------------LDEKASKLYSISSQVSSAVMKSLLCLPSSMSWGQT------P
CSPKEGGSPASSAGDTPAMNPSAET-ALDTGFSLNLSELREYTEGLGEPTEADSWD----
--HCSPQSGQSVIKLLSSDELKKLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLA
GGADLENKVITVHR---------VFPNGLASQEGTI----------QKGNEVLSINGKSL
KGATHNDALAILRQARDPRQAVIVTRKPALEAAPDLNSSTDSTASASVASDVSVDPSKCP
ELAEATVHTVTLEKTSAGLGFSLEGGKGSLL-----GDKPLTINRIFKGAASEQSETIQP
GDEILHLAGTAMQGLTRFEAWNIIKTL-----------PDGP--IMMVIRRKGLQSKGIT
AAGDA----------------------
>gi|126337936|ref|XP_001365925.	Monodelphis domestica
------------------------------------------------------------
---------------------------------------MKVTVCFGRMGIVVPCKEGQL
RVRDL---TQQALQRYLKAKEKDPGDWVKIHHLEYMDG--GILDPDDILADVVEDKDKLI
AVFDEQE--SIHKVESPSGNLTESH-----------------SPDSFDAEVATQLAAFKP
IGGEIEVTTSALKLGTPLLVRRSSDPALSPPADSHPGASHPSDQNLKPVVPGSPQ-SLED
GEVMFSGQPELQTSQNAKHTSSD-----MTRTVEISGEGGPLGIHVVP-FFSSLSGRILG
LFIRGIEENSRSKRDGLFHENECIIKINNVDLIDKTFAQAQDVFRQAMKS----------
---QNVLLQVLPPNNREQYEKSVIA----PLGIFGNSD-AASRTKASPPI----------
-------------------QGKPALKTISPTGASSPETNTQISLQQKR------------
-------------------------SPRIPRVGRKPSSPSLSPLMGFGSKKNAKKIK--I
DLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGR
TQEELVAMLRST--KQGETASLVIARQEENFLPRELKGEPDHCYVLSLETPEQLTF-EIP
L-----------------------------------------------------------
----NDSGSAGLGVSL---KGNKSRETGADLGIFIKSI-------------------IHG
GAAFKDGRLRMNDQL---IAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRL
DRQTEDRSDYGLFP-----------------KPSL-----------ESCQHFVTTSRHHE
PNPHPFLTYGPQERQ---KELLLPDTDWAENDIPPPLPPHPSLELDLEDYNHSSVVDSAV
YCTDQQI---NFRSLTPAKQPESINLKASKSMDLVPDESKVHSLAGHRLEPTAKDFGPTL
GL----------------KKSSSLESLQTAVAEVRKNDLPFHRPRP-----H--MVRGRG
CNESF-----RAAIDKSYDGPENLEEDGLSDKSSRSGQGALNCESNPQGNAVLEDIEN-K
AKKDKKNKDKEKKKEKGKLKVKEKKRKEDSEDSEKKVKKKGFGAMLRFGKKKEDKG----
--GKNEQKGNLKQGIL-QEELEKMKEESERIGAKHQELREKQARGLIDYSAGLLGTLHDM
DDDEMDPNYARVNHFRDTYVPAGVYRSSSPPRIGTLGYLRDGPPLSLEKDPLEGLYAKIN
KPYHPQTLADSGRPTSGSTDRIQKLRKEYHQARREGFSLYEDEELRARPSDYEQHWVSGK
S-PDGSSHNLRIEGMERQCASLPRRGPTDPTDYLTGPPRLIYKERELPYYPGVQPLHPPK
GSYPP------TQELRYPQYYPAPPASHHKGPYRHDVPPSPPQHPRVPAYHELGTTGQRA
ASHEQYPYR--DPRQKNPMTAAV----
>gi|110645183|gb|ABG81417.1|	Gallus gallus
------------------------------------------------------------
---------------------------------------MKVTVCFGRTGIVVPCKDGQL
RVRDL---TQQALQRYRKAQEKDPTYWVNIHHLEYTDG--GILDPDDVLADVVEDKDKLI
AVYDEQE--PHRKSDGTNGNVTDRS-----------------SPDLFEAEVAAQLAAFQP
IGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFED
GEMNLAGPTELLSSQRARLPVSE-----MTKTVEISGEGGPLGIHVVP-FFSSLSGRMLG
LFIRGIEDNSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKF----------
---QSVVLEVLPPYNREQYEKSAIA----PLCFLHNDE-EVPKTKIPPPV----------
-------------------HPKPTLKTINLSGAGSLDAGVLATLQAK-------------
-------------------------SPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIK--I
DLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGR
TQEELVAMLRST--KQGETVCLIVARQEEAFLPRELKGEPN-CSALSPETTEQLTF-EIP
L-----------------------------------------------------------
----NDSGSAGLGVSL---KGNKSRETGADLGIFIKSV-------------------IHG
GAAFKDGRLRVNDQL---VAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRL
EAQTEERLDQGVYQ----------------KSAF---------------DGSHNFAAISR
RNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAV
YLADQHI---NFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTL
GL----------------KKSSSLESLQTAVAEVRKNELPFHRPRP-----H--VVRGRG
CNESF-----RAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKV
KKEQKKVERQRRHKEKGKTKIKEKK-----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------GKKKM-------------------
------------------------------------------------------------
---------------------------
>gi|115760325|ref|XP_790732.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
-----------------------------------------MIIAIIIITVSIITIAIMT
IAITIIIITVTTIAIIMIITIVIVNTVIIITIADDDG------------RKGKSKASQEI
ALQNEAS--TIPAVLNNQSLSLLVI--------------GGIDKDGRPRVTNMRPGGVAH
RSDVLQTGDFITSVNNVKTVTLRHDEVITLLKNV-GNKVSLEIEYELP------------
------VYSKTPLSPSTGYSKTL-----DIRLTREDGS---YGFTIRG-GVNANSSKTRP
LVVTHIRPGGPGDREGSLKVGDRLVAVETTNLGQASHMEALNIIRQGGNS----------
------------AVLRFEYDVSIM---------------EAVKNATGPLL--------VE
VSKTPGAHLGVGLSSIPR-NGKAVIIIDNLKPASIADRCGALHIGDEILTID--------
-------------------------GLTTTHMG----VAEAMKLLASGTEQVKLEILPVS
QMT------PRLTYSRDMQKLGGQPSRSTTPLMPGYSHSSLS------RVGTMNSQNTRQ
QSSTLARKLRSKGHKTGSMLSLASTIN------------GLSSPQVCHTDSVDVTL-YSR
TGDYGIQLQSGVFATEILGSPAVVGFVEPGGKA---------------------------
----EKSGVMQPGDRLIAINGSYTEDMTADEANHILRE-------SAPQVTLEIEFDIAE
SVVPSSGVFNVK------LPVSEMGLGIT-----LTSLKHRRLGDGLLISTVKKGSVANR
SGTLEPGDQVLAIDDIHLDSITVEEAMHLLAQADEIVKLKVKKNEAYSDE--PDVSGAIS
YSVELVRHGGPL------GITISGTEEPFDPVIISGLTENGLAE-----------RTGAI
HLGDRLLAINGVSLKGKTLSEAIRLLQSAGDTVVLKISKKEKHRGHDQGNKPSSRSQS--
-----------------PSRFSRVATHYDAD----------HIATP-----VMIQTNGDS
WEGSG--------MDTGYHSNHTHHSRSHSPKTSRSRRSSMS-----------------P
SRRSNRPRRVHNSSHSTSPNDASEDELDERRRAFVNGANGSYPVDILSSDQDDSY-----
--------AHSQHSYHPHEAQIAKHREFLRQLEASFLNTDQFTSSEMRRAGSVGHGYYLN
QPGTVGGR--------------------------------------KPSTSSLQMYSDSS
HSYTLPPHAPTGGGGGG-YNQFESFSSKSESVNTTHQNVMNQNDASHLGDESTVSEAPNP
APVELHKVSLKKDSDVEDFGFSVSDGI---------SDKGVFVNTVRPGGPASRSGNVKP
FDRILQINQTRTHD---FDCCMVVPLI-----------ADSGNKLELVISRNPMAKHQNG
GGDEEGSWSGVENGHFVQMQPAAAAQF
>gi|118789970|ref|XP_317940.3|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
---------PPAFSRLPPDGHEFPPNFT--------------------------------
---------EPTTTTATNGNSSSGV------------------------SMPPSSGIFAA
FNDDLPDLP-------------KSHPPPVPRKSVFEQRR---RSVDVP------------
-----------------------------------DHNGKGAAPSLPPSGRISLVG----
-------SNWRKDEKSEKSVRDKIAMFSSAADAEGGVAPVPQQHAATTTA----------
--ANNPSALLTASRNLETSKPVVLGK---AYSVENLNPANRSSDTNGSKI----------
--------LSRTTSFSGYSNGNSLATIASSPAASVGGSTNSLTALQNN------------
-------------------------TPAASDERWKSSISSLLE----QRKKSMSKLRGL-
------------------------------VIPEKSKDSEIILSSA--KPPSAVTDAYSR
RTSTLPMPPKTSL-SSLTASTIVARSVAAIEPELPAFRKPLVVPPLPPAKPPRTSLVYPP
------------------------------------------------------------
----KSGSTDCLRSTE---DDDESDDGDGDESDSVLSS--RVSSPPKYALTRTLSSETNT
SITSSNSTLTSSSGS-----QASCSSVGST--PTVDISRKLSKSSSSEASMNRKNVLASA
KSRNGQRRKSKS------------------KPRSSLTNGKGASYEQERKELTHYKVVDSV
DGSSIVDKVIKVASYVEVVSDLEDSSIVEEPIIVGALGARGERKQQPPPPTPPRTVPPPP
TEPVPVPVRRELRSSVETKKLNLAEIRKSFESKSANIVAPPATPPVHATPKTTTNNGHDR
F-----------------SSWDSLASSSSGVSSLQTNSLGMGRGAPNCTGSFSSLGSSHS
LITPQDLQLIIEEADPPLATPEAFVVVLQRETPESSIGITLAGGSDYEA----------K
EITIHKILTNSPADRDGRLR-KGDRILSINGLSMRGLTHRESLSVLKTPRPEVVM-----
------------VITRSKSLVLDTLTKLKRPSMGSLSSLAEKSEIATEYERKLKIQHKAS
RSLDLDHLDVASN---------------------------------EGKSKVCSMVPHPR
MGYCRPTTSPNVPPA---MPPTMVSDTTVLQAAIEYYIDRVSHSASTASSYSTAE-----
--VPEGCRMVEINKDGAGLGFSIEGGYDSPA-----GNKPLIIKKIFMGGAAEKSGLLRA
GEEIVAINDISIAKMTRIQVWNMMKKL-----------PNGG--VRITLK----------
---------------------------
>gi|149632975|ref|XP_001507817.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
----------------MHSLVEDPDYWVKIHHLEYTDG--GILDPDDVLADVAEDKDKLI
AVFDEQE--PMHKIDNSGGNLSDRP-----------------SPDALETEVATQLAAFQP
IGGEIEVTPSALKLGTPLLVRRSSDPVPCPPADSLPAA-HLNDSNGKPLVPSSAQ-NLDD
EEVVFAGQTEVVISPKSKYTFSD-----LTRTVEISGEGGPLGIHVVP-FFSSLSGRILG
LFIRGIEENSRSKRDGLLYENECIVKINNVELVDKTFAQAQDVFRRAMKA----------
---PNVLLQVLPSQNRDQYEKSVIA----PLCIFVNDN-GISKTVMSPPV----------
---------------------QPAGRMADLNGTSNMETAASSSLQQSK------------
-------------------------SPRVPRVGRKPPSPSLSPLMGLRSRKNAKKIK--I
DLKKGPEGLGFTVVTRESSVHGPGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDIMGR
TQEELVAMLRST--KQGEIVSLVIARQEESFLPRELKGEPD-CWALSLEATEQLTF-EVP
L-----------------------------------------------------------
----NDSGSAGLGVSL---KGNKSRETGADLGIFIKSI-------------------IHG
GAAFKDGRLRTNDQL---IAVNSESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVVLRRM
ERQIEEYPELRTFQ----------------------------KAAGENCQ---NFATTSR
HSDVTPQTVVAYSPQDKQKGMLLSNEDWTETELPPALPPHPNLGLVFADRNPSSVVDPTV
YFTDQHI---NFRSLAPAKQPESINLKASKSMDLVPDESKVLSLVGHRSESPGKDFGPTL
GL----------------KKSSSLESLQTAVAEVRKNELPFHRPRP-----H--MVRGRG
CNESF-----RAAIDKSYDGPEDLE-DALSDKSSHSGQETLNCSSVPQGNTELEA----K
AKKNKKYKEKEKKKEKSKSKVKEKKRKEENEDPEKKAKKKGFGAMLRFGKKKEDKG----
--GKAEQKGGPKHGSLREDELEKMKEERE-------------------------------
------------------------------------------------------------
----------SSRSTSGSADRIQKLRKEYHQARRDGFPLYEDDEGRARPSDYEQHWVPGK
G-PDGSSCNLRFEGMERQYASLPRRGPAEPAEYLT-GPRLIYPERELPYYPGVPPLAPSP
KGSYPRTQDMWGPDLRYPQYYPPPSAPQHKGPFRQDVPPSPPQCHKVPAYHEMGRTLYRG
VSPDQYHSGTQDPRQKNPMTAAV----
>gi|110749753|ref|XP_393571.3|	Apis mellifera
------------------------------------------------------------
-------------------------------------------MATRTEDTTSIDNTNDG
ESMDKEVLAISGNDE---TNHRIPPTYLYNSGSEQNT----GISNQEQNNKNRTQT-SED
QLGPLPP--NWEKAFTDTGEVYFID-----------------HNTGTSHWLDPRLSKFQK
RSLEECL------DDELPYGWEKIDDTLYGTYFI--DHVNRRTQYENPVLQAKRAQQNLG
ERKSPNFTRN----PDKLKGQKI-----RTTLIK---STRGLGFTIVG-GDDSVEE---F
LQIKSVVPNGPAWLDGKLQTGDVLVYVNDTCVLGFTHNEMVNVFKSISSG----------
-------ETVTLEVCRGY---------------------PLPFDPNDPNT---EVVTTIA
VNTPEDPRLYMDLDPALQSNSRFNFLDSTFLPVHNLQNDSSTSSKPEFLSI---------
-------------------------AIVKGTMGFGFTIADSAHGQKVKKILDRQRCKNLM
EGD-------ILVNINDINVRNMCHSEVVQVL-KDCSRNEEALIHVQRTTSKSNEKKEKN
SQDFFRSKTPTADIYSTQTKTVVPSRPK--------------TPLIDTRNRP-----KSP
S-----------------------------------------------------------
----NDDSV----------RNSTKRDWVTNEKLNINND------------------VYSI
DIPHHDNMLKQNGCLHSDYYKDLYTSQSHSQYSEQDYNVYSIGQEQNVDTG---------
-------------------------------EIWD-----------KRKE--TTSFEHEQ
PHSSSIPRYPQYNNEL--VCPIVPDIEWIETLVTLIRQDTG-------------------
-FGFRIV---GGTEEGSQVSVGHIVPGGAADLDNRLNTGDL-------------------
------------------------------------------------------IMSVDG
--------------------------ESVMNSSHHHVVQLMIAAAQ-------------N
GRVTLGIRRRINTQEHLPDNLQT---------SYNRQMNLQYPCDVT-------------
----------------------------------------------VTRMENEGFGFVII
SSVNKAGS--TIGR---------IIEGSPAERCGRL----------NVGDHILAVNHVDI
TNVCHKDIVNLIKDSGY--SVTLTIGYPLDDCCSNTSLSQKDEPTCDGDGGQ--------
------YHAVELTRGTRGFGFSIRGGREF-------QNMPLFVLQIAENGPASIDNRLRV
GDQIIEINGINTKNMTHTEAIEII--------------RNGGPSVRLLVRRGCQMPSVVG
APPHLYDMNI-----------------
>gi|114658507|ref|XP_001157454.	Pan troglodytes
------------------------------------------------------------
------------------------------------------MESHSRAGKSRKSAKFRS
ISRSLMLCNAKTSDDGSSPDEKYPDPFEISLAQGKEGIFHSSVQLADTSEAGPSSV-PDL
ALASEAA--QLQAAGNDRGKTCRRIFFMKESSTASSREKPGKLEAQSSNFLFPKACHQRA
RSNSTSVNPYCTREIDFPMTKKSAAPTDRQPYSLCSNRKSLSQQLDCPAGKAAGT----S
RPT-RSLSTAQLVQPSGGLQASV-----ISNIVLMKGQAKGLGFSIVG-GKDSIYG-PIG
IYVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRL
TAPPSLCSHLSPPLCRSLSSSTCITKDSSSFALESP---SAPISTAKPNY---RIMVEVS
LQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEISDSPVHCLT
LNEVYTILSHCDPGPVPIIVSRHP-DPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVK
RLESSWHGRPTLEKEREKN-SAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSS
DVDISTHSPSLPLAREPVVLSIASSRLPQESPPLPES--RDSHPPLRLKKPFEILV-RKP
TSSKPKPPPRKYFKSDSDPQKSLEERENSSCSSGHTPPTCGQEARELLP---LLLPQEDT
AGRSPSASAGCSGPGI---GPQTKSSTEGEPGWRRASPVTQTSPIKHPLLKRQARMDYSF
DTTAEDPWVRISDCI-----KNLFSPIMSESHGHMPLQPNASLNEEDGTQGHPDGTPPKL
DTANGTPKVYKSAD----SSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQ
PAPASREHLGSHIRASSSSSSIRQRISSFETFGSSQLPDKGAQRLSLQPSSGEAAKPLGK
HEEGRFS---GLLGRGAAPTLVPQQPEQV-LSSGSPAASEARDPGVSESPPPGRQPNQKT
LP-------------PGPDPLLRLLSTQTEESQGPVLKMPSQRARS-----FP-LTRSQS
CETKL-------------LDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQT------P
CIPKEGASPTSSSNEDSAANGSAETSALDTGFSLNLSELREYTEGLTEAKEDDDGD----
--HSSLQSGQSVISLLSSEELKKLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLA
GGADLENKVITVHR---------VFPNGLASQEGTI----------QKGNEVLSINGKSL
KGTTHNDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVEST---
--AEATVCTVTLEKMSAGLGFSLEGGKGSLH-----GDKPLTINRIFKGAASEQSETVQP
GDEILQLAGTAMQGLTRFEAWNIIKAL-----------PDGP--VTIVIRRKSLQSKETT
AAGDS----------------------
>gi|54038482|gb|AAH84451.1|	Xenopus tropicalis
------------------------------------------------------------
---------------------------------------MKVTVCFGKTGIVVPCKDGKM
SVRELI---QQAAQRFIKAKEKEPGYWVKVHHLEYQDG--GILDPDDIVADVVEDKDKII
AVFDEQEASEIKNRNEDSVNVIDRT-----------------SPDPLEAELSAQLSAFQP
LKGEIDVTSSALKIGTPLLVRRSSDPTVGPAVDFHPSSSQSADQNVNDA----------S
QGLSRVLPPDEQTDQNTGLQKPLYKIREITRKVEISGSGGPLGIHVVP-FYSSFSGRALG
LYIRGIEESSRSKREGLFQENECIVKINNVELIDRSFAQAQDIFRQAMKQ----------
---QNVLVETVLPEKRELYEKSVISS---LFVLDDDIDEVPDIKPPPPPV----------
------------------------------------HVNRSIKMPEQVNGID--------
--------------PTGTKIQQPPLSPNLISSESKFSSPSLSP-LGFGNKKNGKKLR--I
DLTKGAEGLGFTVVTRDSTVHGPGPIFVKNILPKGAAVKDGRLLSGDRILEVNGKDIAGK
TQEELVAMLRST--KLGESVSLVVARQDETFLPRELKGETE-NLVFPPDNTAQMTF-EIP
L-----------------------------------------------------------
----NDSGSAGLGISL---KGNKSRETGADLGIFIKSI-------------------IHG
GAAFKDGRLRVNDQL---VAVNGESLLGKSNRDAMETLRRSMSMEGNIRGMIQLVILRRL
DWQTEERSETFQKN--------------------------------------TIENLAVS
EQNGVQEKL---------KDSSRFNDRNSENYIPPPIPPHPKEHIIVESP----------
----------KLRNVAESQPNDSLNIKASRSMDIVADESNIGSLREHQSGSPGKDFGPRL
GL----------------KKSSSLESLQTAFAEVKKNELPFYRPRP-----H--MVRGRG
CNESF-----RAAIDKSYDGPEGEEEDALSDLSSHSGRESPNSELTPLGNQ--------E
MEDTDKSKKKKKKKK---------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------
>gi|73951277|ref|XP_860817.1|	Canis familiaris
------------------------------------------------------------
------------------------------------------MDPHSRSGKSRKSTKLRS
ISRSLMLCNAKTSDDGSSPDEKYPDPFETSLGQSKEGIFHSSVQLADTSEAGRGSV-PDL
ALASEAT-------GSDRGKSSRRIFFMKEAATTSSREKSGKADTQSSHFLLPKARHQRT
RSNSTSVNPYCMGEIDFPMIKKSAACTDRQPYSLCSSRKSLSQQLDCPAGRVAGT----S
RPT-RSLSTAQLAQPSGGLQASV-----ISNIVLMKGQAKGLGFSIVG-GRDSIYG-PIG
IYVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRL
TTPPSLSSHLSPPLCRSLSSSTCAAKDSSPLGLESPATLATPASTAKPNY---RVMVEVS
LQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCMT
LNEVYAILSHCSPGPVPIIVSRHP-DPQVSELQLIEAVAQAVENVKFGKERHQWSLEGVK
RLESSWHGRPTLEKEREKN-SAPPHRRAQKVMIRSSSDSSYMSGSPGGSP-ISGCEQLTS
DPEVPTHSPSLSLGQEPGALPVALSRPPQESPPLPGM--PDSHPPLRLKKSFEILEARER
LPPPPLPLPQE-----------------------------------------------DT
AGRAPHALACCPGPTV---DPHTAPSSEPEPGRRRGSPGTQTSPVKHPLLKRQARMDYSL
DITAEDPWVRISDCI-----KNLFSPIMSENHSHVSLPPSVGLGGEDGPRGHPDGTPPKL
DATSGASKAYKSAD----SSSVKKGPPVAPKPAWFRQSLKSLRTRAAEPRRLPDTASSSK
PAPASRERPGAPTRAF--SSSIKQRISSFETFGSAQLPNRGAQRLSLQASMGEAAQSPGE
QDGGQVP---GLSGRGPPHTVEQQQPEPEPLPRGTLTSSKTSELGVSGSPLPGRQSSRET
LL-------------PDPDPLSRLLSTHTEEAQGPVVKMPSQRARS-----FP-LSRTQS
WEMKP-------------LDEKASKLYSISSQVSSAVMKSLLCLPSSMSWGQT------P
CSPKEGGSPASSAGDTPAMNPSAET-ALDTGFSLNLSELREYTEGLGEPTEADSWD----
--HCSPQSGQSVIKLLSSDELKKLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLA
GGADLENKVITVHR---------VFPNGLASQEGTI----------QKGNEVLSINGKSL
KGATHNDALAILRQARDPRQAVIVTRKPALEAAPDLNSSTDSTASASVASDVSVDP----
--TEATVHTVTLEKTSAGLGFSLEGGKGSLL-----GDKPLTINRIFKGAASEQSETIQP
GDEILHLAGTAMQGLTRFEAWNIIKTL-----------PDGP--IMMVIRRKGLQSKGIT
AAGDA----------------------
