>gi|47225899|emb|CAF98379.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
--------------SVPVSELVAVREEEEENRD--DGSWK--------------------
---KIKESEGQDCG------------------------------------QAFTVLY---
--VER-CQRH-RWRCAEVTFACADEALCQLWVS-----SIREQLA------------TNT
SRP---EHLLVYINPCGGKRKAEHIYELKVAPLFARAG-IRTHVIVTEYANHARDHLKTE
A--ELKKFDGVVCVGGDGMFSEIIHGLIWRTQIDNGIDLNCP-EETLLPCSLRIGIIPAG
STDCI---------CFATVGTNDPVTSALHIIVGD-----SQPLDVCSVHHNSL----FL
RYSVSLLGYGFYGDVLTDSERKRWM-GPARYDLSGVKMFLTH--HYYEGTVSYLPAR-DA
I----------GTPRDAAR-------CRSGCAVCK-------------------------
------------------------------------------------------------
-------HNGEKLSETAER--Y------------------------KMDGALDSGDHE--
SDSEWRTIRGKFLAINGASMSCACP--RSPKGLSPAAHLADGTTDLILVR-KCSRFDFLR
HLLRHTSKDDQVLGLGSPAGWARTCRSNALSSLQFDLNFVEVHRVRR-------FRFT--
-----------PRHCQSDSDLELDLRESGKRQI----FSQICRDHPA---CGC----TPA
YSSWNCDGEILTHTAIDVRYGSRRGVFGGGVCRLWRALLSRSFLFPRVHCQLIKLFARGI
EE------------------------------------
>gi|114686947|ref|XP_001137835.	Pan troglodytes
--------------------------MGATGAAEPLQSV---------------------
------------LWVKQQRCAVSLEPARALLRWWRSPGPGAGAPGAD-------------
------------ACCVPVSEIIAVEETDVHGKHQGSGKWQ--------------------
---KMEKP------------------------------------------YAFTVHC---
--VKR-ARRH-RWKWAQVTFWCPEEQLCHLWLQ-----TLREMLE------------KLT
SRP---KHLLVFINPFGGKGQGKRIYERKVAPLFTLAS-ITTDIIVTEHANQAKETL-YE
I--NIDKYDGIVSVGGDGMFSEVLHGLIGRTQRSAGVDQNHP-RAVLVPSSLRIGIIPAG
STDCV---------CYSTVGTSDAETSALHIVVGD-----SLAMDVSSVHHNST----LL
RYSVSLLGYGFYGDIIKDSEKKRWL-GLARYDFSGLKTFLSH--HCYEGTVSFLPAQ-HT
V----------GSPRDRKP-------CRAGCFVCR-------------------------
------------------------------------------------------------
-------QSKQQLEEEQKKALY------------------------GLEAA------E--
DVEEWQVVCGKFLAINATNMSCACR--RSPRGLSPAAHLGDGSSDLILIR-KCSRFNFLR
FLIRHTNQQDQ-----------------------FDFTFVEVYRVKK-------FQFT--
-----------SKHMEDE---DSDLKEGGKKR-----FGHICSSHPS---CCC----TVS
NSSWNCDGEVLHSPAIEVR----------------------------VHCQLVRLFARGI
EENPKPDSHS----------------------------
>gi|73969242|ref|XP_531694.2|	Canis familiaris
-----------------------MDHHPPPGPCRPLPPT---------------------
--------------SVRTPQAFPEPLATPGLRLDAC------------------------
--------------SVPISEIITVEETDTRGKHYGSGKWQ--------------------
---KMEKP------------------------------------------FAFTVHC---
--VKR-ARRH-RWKWAQVTFCCAEEPLCHLWLQ-----TLQELLD------------KLT
SRP---KHLLVFINPFGGKGQGKRIYERKVAPLFTLAS-ITTEIIVTERANQAKESL-YE
I--NIDKYDGIICVGGDGMFSEILHGLIGRTQRNAGVDQNQP-RAALVPSPLRIGIIPAG
STDCV---------CFSTVGTNDAETSALHIIVGD-----SLPMDVSSVHHNST----LL
RYSVSLLGYGFYGDIIKDSEKKRWM-GLIRYDFSGLKTFLSH--HCYEGTVSFLPAR-HT
V----------GSPRDRKP-------CRAGCFVCR-------------------------
------------------------------------------------------------
-------QSKQQLEEEQKRSLY------------------------GLENT------E--
EVEEWKVVCGKFLAINATNMCCACP--RSPSGLSPAAHLGDGSSDLILIR-KCSRFNFLR
FLVRHTNQYDQ-----------------------FDFAFVEVYRVKK-------FQFT--
-----------SSHMEEE---DSDLKERGKKR-----FGQMCSEHPS---CCC----SVS
NSSWNCDGEILSSSSIEVR----------------------------VHCQLVRLFARGI
EENPKEELDS----------------------------
>gi|109125409|ref|XP_001113936.	Macaca mulatta
---------------------MNGLLEAEEQDQRPEQEL---------------------
----TRSWGHRPRSTLVRAKTMAPPPPPLAASTPLLHGEFGSYPARG-------------
---------------PRFALTLTSQALHIQRL----------------------------
---RPSDSAAYFCI------------------------------------YTYPRSRR--
--GSR-RRTTRTFRTDGATTYEENRAEAQRWAT-----ALTCLLRGLPLPGDGEITPDLL
PRP---PRLLLLVNPFGGRGLAWQWCKNYVLPMISEAG-LSFNLIQTERQNHARELV-QG
L--SLSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVK-------------MPVGILPCG
SGNALAGAVNQHGGFEPALGLDLLLNCSLLLCRGG-----GHPLDLLSVTLASG----SR
CFSFLSVAWGFVSDVDIQSERFRAL-GSARFTLGTVLGLATL--HTYRGRLSYLPATVEP
TSPTPVH----SLPRAKSE-------LTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALAS
PGSPEPLPILSLNGGG-----PELAGDWGGAGDAPLSPDPLLSSPPGSPKTALHSPVTEG
APVIPPSSGLPPPTADARVAAS---------------------TCGLPDHLLPPLGTP--
LPPDWVTLEGDFVLMLAISPSHLG----ADLVAAPHARFDDGLVHLCWVRSGISRAALLR
LFLAMERGSQFS----------------------LGCPQLGYAAARA-------FRLE--
--------------------------------------PLTPRGVLT-------------
-----VDGEQVEYGPLQAQ----------------------------MHPGLGTLLTGPP
GCPGREP-------------------------------
>gi|156541858|ref|XP_001600118.	Nasonia vitripennis
---------------------------MQENANEEDPSY---------------------
----HTVLLSTFVIRKKRCRVYF---HKGTLIWETERPPYTRW-----------------
--------------TLPLTDVLTATYGDDVRVSGLTGTSNEAFRDKEKESQASAP-----
---TSPSSTTPNSP------------------------------------TSFVLHY---
--AAQ-GAKN-KWSHHSVTMNHDDPRQVSSWVK-----TIRNYLA------------SKK
LRV---RIILLFVNPFGGKKKGLHIWEKRVQPLMGIAG-VEAKVIVTERAGHIRDVL-LN
C--ELDSYQAAVCVGGDGTFAELFNGLIARTARDQRIDLNDP-DVLLPKPTLPVGVIPSG
STDTL---------AYSLHGTTDVETAVIHIVFGD-----SAGLDVSSVHNEKN----LL
RIYASIFSYGYLGDVIRDSEKFRWM-GPQRYDYSGFKKIIAN--KGYEGEVVLLSDP---
-----------GHPAACER-------CTKNCARCI-------------------------
------------------------------------------------------------
--------------EISHNGTV--------------------------------------
DDDKRLTVRGKFFMVNGANISCACS--KSPMGFSPHCHIGDGCVDVILVR-HTSLINNIR
MLFRLSSKDKTL----------------------YDLPFVEVYRARE-------FTFK--
-------------------ASNPGSNQQQRQQSYENSTTTGPRSNLG----------SSA
LSVWNCDGEVIDASSVKIR----------------------------AHRQLLKVYTRRM
QPEPRPNPSCFCLL------------------------
>gi|126002580|ref|XP_001382211.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
------------------MNILRVVRNNWKKSAFAAAVSG--------------------
--------------------------------------------------YALSSLK---
-------------THIEITQYMSEFSTNLSSTS------------------------ENV
GAP---KNVLVVMNPIANKKKSEKTFKKYCEPILHLAG-YSVEILRTNHIGHAKAYI-EE
M---ANLPDAIVIAGGDGTSSEVVTGLMRRNENV-----------------CPITILPLG
RTNQATHKYFQIGVQSELDYIKSLCSALLPMLKDDFMYQSVIRYDVINNDDDSEKHL-KP
IFGLNGFSWGLLKDIDSTKEKYWYF-GPIRHYVAAVSKLFSN---NWSLETDYVYTP---
--------------------------PCAGCLDCV-------------------------
--------------------------------------------------------EVRN
EESRFLNNFLGKLVNPNRSNMK------------------------PQRQLVKNSEC---
SSKQQGKMEANQIDINCI---------QNSENFSELE----TQ----FISSLQPGWDFIK
TIPSITSS--------------------------TIVPQL-VLRSRT-------IQLH--
-------------------------------------PTGETTNVYS-------------
-----IDGEEYDARPIKLS----------------------------VVPNAIKVFC---
--------------------------------------
>gi|50293103|ref|XP_448973.1|	Candida glabrata
-------MRHEVAVRATVTDAGIKIKSQTRGFCCPEVVH---------------------
----KPQGLSSILGGCFLSCCAPLGVNDAELSLDPDNSTFSMDEDIA-------------
-------EAPTVSDTIPFGRILGARYRDSSANSQTHETEG--------------------
---LLHGIGHQRYID-----------------------------------LTYACMKD--
--HHV-VPCTVPLQIDYVPMAHENPDLVELIIE---------------------KSYQNV
KRN---RSILVIINPHGGKGKAMHIFKKRIEPILIASE-CSFELMETKYSRHATDIA-RE
I--DLEEFDTIACASGDGVPYEVINGLYMREDKVDAFNK------------ITVTQLPCG
SGNAM---------SISCHWTDNPSFAALCLVKSV-----ESRIDLMLCTQPDSEDP-EP
KLSFLSQTYGVIAESDINTEFIRWM-GPLRFDIGVAFNVLQK--KCYPCDIYVKYAA---
-----------QSKRELSV-------HYTKNKTTQ-------------------------
------------------------------------------------YLEFENLITETD
TESSDSGIPVENITEENLRIKY------------------------PVEDG---------
IPNDWVKLDDEIGNNLSVFYTGKMPYVAANTKFFPAALPADGTFDMIIMKANLPVAKSFP
ILLSIDKGEH------------------------VLDSEVIHSKVLA-------YKII--
--------------------------------------PKIENSLIS-------------
-----IDGERFPCKPLQVE----------------------------VLPKLCKTLLRNG
KYIDTDFDMLCADTKLP---------------------
>gi|151945788|gb|EDN64029.1|	Saccharomyces cerevisiae
----------------------MVVQKKLRAILTDEGVLIKS------------------
----QSHHMFNKHGQLRSGDSLFLLSCLSCLDDGTLSSDGGSFDEDD-------------
---SLEL--LPLNTTIPFNRILNAKYVNVGQKGFNNGKISSNPFQTENLSSSSENDDVEN
HSLSNDKAPVSESQSFPKKDKWDTKTNTVKVSPDDSQDNSPSLGIKDNQQLIELTFA---
--VPK-GHDVIPQKLTLLIDHVSRKSRANTGEENISSGTVEEILE---------KSYENS
KRN---RSILVIINPHGGKGTAKNLFLTKARPILVESG-CKIEIAYTKYARHAIDIA-KD
L--DISKYDTIACASGDGIPYEVINGLYRRPDRVDAFNK------------LAVTQLPCG
SGNAM---------SISCHWTNNPSHAALCLVKSI-----ETRIDLMCCSQPSYMNE-WP
RLSFLSQTYGVIAESDINTEFIRWM-GPVRFNLGVAFNIIQG--KKYPCEVFVKYAA---
-----------KSKKELKVHFLENKDKNKGCLTFE-------------------------
-------------------------------------------PNPSPNSSPDLLSKNNI
NNSTKDELSPNFLNEDNFKLKY------------------------PMTEP---------
VPRDWEKMDSELTDNLTIFYTGKMPYIAKDTKFFPAALPADGTIDLVITDARIPVTRMTP
ILLSLDKGSH------------------------VLEPEVIHSKILA-------YKII--
--------------------------------------PKVESGLFS-------------
-----VDGEKFPLEPLQVE----------------------------IMPMLCKTLLRNG
RYIDTEFESM----------------------------
>gi|66505029|ref|XP_394823.2|	Apis mellifera
---------------------------MEDSGQIHSTLL---------------------
----EETFYVTSK----KNTYYKVRLTEKGLSLEKDNNGTTKVE----------------
--------------TIVLNDIIGCRCMRSKRKSAGSCVCGPGTSRSQFKLVESAEAYQCY
---DEFDTSAYLYI------------------------------------YAYTLKKARM
KGVKRRERTTITLRFRSFDKYEDNLREASRWRL-----AIKCLIVGVPVPK------SFM
TCPGEQRKILVLLNPKSGPGRSRETFQKRIHPILSEAE-RPYEVHVTKCPNYAREFV-HT
R--DIYQWSGLVMVGGDGIVFDVVNGLFQRPDWEKALKE------------LPLGVIPCG
SGNGLAKSIAYA--KQEPYDYNPLLISALSVVKFK-----KAQMDLVRVETRNQ-----I
LFSFLSVGWGLLADIDIESERLRAI-GGQRFTVWTIARLIGL--RTYKGKVSYLPCDKVP
SVESL------GNGNAYNEYTKETQISYSKISESK-------------------SFHDTL
DGDPAILDGSSDIYDDNEIISENITLETEIERRQRLDSFYSATSAKSTYFSTGSISSYHS
VDEPDNENIGKSSTYSNSQVMY------------------------GPSSRLPALTSE--
VSSSWTQIQGEFVMVHAAYQSHLG----QDYFFAPRAKLADGIIWLMIVKAGITRANLLQ
FLLGLSNGSH------------------------VTRSGIDMIPVKA-------FRIE--
-------------------------------------PEEGVNGYIT-------------
-----VDGERVDYGPLQAE----------------------------IFPSLATVMSP--
--------------------------------------
>gi|149743449|ref|XP_001488792.	Equus caballus
------------------------------------------------------------
-------------------MDGPYDDDNNDASWDAC------------------------
--------------SVPVSEIITVEEQDVHGKRSASGKWQ--------------------
---KMERL------------------------------------------YAFTVHY---
--VQR-ARQH-RWKWTKVTFCCADEQLCHLWLQ-----TLRELLE------------NLT
SRP---KHLLVFINPFGGKGQGKRIYERKVAPLFALAS-VTTEVIVTERANHAKDSL-YE
I--NIDKYDGVVCVGGDGMFSELLHGLIGRAQRNAGVDQNQP-RATLVPSPLRIGIIPAG
STDCV---------CYSTVGINDVETSTLHIILGD-----SLPLDVSSVHHNST----LL
RYFVSLLGYGFYGDIIKDSEKKRWM-GLARYNFSGLKTFLSH--HCYEGTVSFLPAQ-HT
V----------GSPRDVKP-------CRAGCSVCR-------------------------
------------------------------------------------------------
-------QSKQQLEEEQKRSLY------------------------GLENT------E--
EVEEWKVICGKFLAINNANMSCACH--RSHRGLSPAAHLGDGASDLILIR-KCSRFNFLR
FLVRHTNHHDQ-----------------------FDFTFVEVYRVKK-------FQFT--
-----------SRHVEDE---DRNLKERGKKR-----FGQICSDHPL---CCC----TVS
NSSWNCDGEILNSPAIEVR----------------------------VHCQLVRLFARGI
EENPQPEPHS----------------------------
>gi|118093518|ref|XP_421973.2|	Gallus gallus
MMGTAGPFLPRGRDRPEERRRRVAPLAAAPPEGEEEPLL---------------------
----RGIFEI-------GKTSCDVVLSARRLRWSPIVPESPAGDSST-------------
-------ALQVKEEIIQMKDVFSVKVKRRRFVGQKKGG----------------------
---TLLGITIFKCL----------------------------------------------
------HKEENKLTDCAIHLNNFSEDHCHSWFR-----RLKEILN------------GFQ
NRP---KSLKVFVNPSSHKREATRIYYEQVSPLFKLAD-IKTDVTVTEYEGHALSVL-KE
C--ELQAFDGVVCVGGDGFVSEVVHGLLLKAQIDAGKGTDYI-P-APVRAPVPLGVIPAG
TTNIL---------AYTLYGIKHTVTATLHIVMGH-----IQPVDACTFSTPSR----LL
RFGFSAM-FGFGARTLALAEKHRWMPSNQRKDFAFIKTLADL--KTEKCELSFLPLQ---
------------------------------------------------------------
------------------------------------------------------------
------------ISQEDSHEND--------------------------------------
SKDQWHKIQGDFLNVSIMAIPCLCS--MAPRGLAPNTRLNNGSMALIVVR-NTSRTEFIK
HLKRYASVKNQ-----------------------FSFPFVETYTVQE-------VKVQ--
--------------------------------------PRIKSGLDAKENTDLNATAAEE
NYPWNIDGDLVEASEVHVR----------------------------VHPQLIHLYGVNT
DDLESSKATCNCI-------------------------
>gi|41054059|ref|NP_956174.1|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MARVVK----
------VFRTLRNHWKKSTFAVCVLSYGGHWLY---GKHCDSVLRREACIEARAFGQQLI
GPQEILKKATVILNPAACKGKANQLFEKNAAPILHLAG-VEVKIVKTDYEGQAKKLM--E
L---MEQTDMLIIAGGDGTLQEVITGLLRRADEEIFSK-------------TPIGFIPLG
SSNSLSQSLH----LVSDNKVQHITSATLSILKGE-----TVPLDVLQIKGEKE----QP
VFALLGLRWGAFRDVATSISKYWYL-GPLKTRAAHWFSSLKQWPQVHVASLSYLAPVPRP
P----------DLPDEIPQRPNLLYRIYRRLQNYW-------------------------
------------------------------------------------------------
---------NPPLEE-------------------------------PPKEP---------
EPEQWESKDVSTLELTVLTHNK-----------NPVKRRVDDSMLISLDPESLTAGQFI-
-----TEGTNKSVD--------------------PMEPIENAVQIEAS-----AARLE--
-------------------------------------LPEEGAGFYD-------------
-----IDNQEYEAMSVEVR----------------------------LLPRKLRFFCSAE
RREQLAEAQ-----------------------------
>gi|8248287|gb|AAF74125.1|	Mus musculus
-----------------------MAPPPLLPVAASTPIL---------------------
----HGEFGSYPA----NGPRFALTLTTQALHIQRLRPKPEARPRDG-------------
--------------LVSLDEVSGCGTLQSR------------------------------
---SPEDTAAYFCI------------------------------------YTYPRGRR--
--GGR-RRATRTFRADGATTYEENRAEAQRWAT-----ALTCLLRGVPLSGDQEITPELL
PRK---PRLLILVNPFGGRGLAWQRCMDHVVPMISEAG-LSFNLIQTERQNHARELV-QG
L--SLSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAVR-------------MPIGVLPCG
SGNALAGAVSHHGGFEQVVGVDLLLNCSLLLCRGG-----SHPLDLLSVTLASG----SR
CFSFLSVAWGFLSDVDIHSERFRAL-GSARFTLGAVLGLASL--HTYRGRLSYLPATTEP
ALPIPGH----SLPRAKSE-------LVLAPAPAPAATHSPLHRSVSDLPLPLPQPALVS
PGSPEPLPDLSLNGGG-----PELTGDWGGAGDAPLSPDPLLPSSPNALKTAQLSPIAEG
PPEMPASSGFLPPTHSAPEAST----------------------WGPVDHLLPPLGSP--
LPQDWVTIEGEFVLMLGILTSHLC----ADLMAAPHARFDDGVVHLCWVRSGISRAALLR
IFLAMEHGNHFS----------------------LGCPHLGYAAARA-------FRLE--
--------------------------------------PLTPRGLLT-------------
-----VDGELVEYGPIQAQ----------------------------VHPGLATLLTGPA
GQKPQA--------------------------------
>gi|76155655|gb|AAX26944.2|	Schistosoma japonicum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------DVITAALHIISGD-----DMSLDVVSVHADNDGA--FI
RYVITMLGYGFHADLLLNDDKRRWM-GPQRYNYSGFMTLLQH--ASYYGEISYLPCL-NQ
N----------NKSSNGTV-------CYRGCSVCASNLHPHHHQTIDYFPDDYPTNKLNV
CHNETDFHVSATSSSLPLRGSSNLSSIPCSLNSNCSSIQGVSNSQTLVISSSSLDSDLGL
SISSNIDNRKVHVSHVLDKSLSEQSLDAKSCDIMSSKQKRFSDTTLNVSQLLTCSLRN--
TTNGWHTIRGTFLAVNAFVQSCRCA--RAVCGPAPWAHLSDGCLDLVLVH-KCSKVQFIR
FLMRIASNRRMTPEENP-----------------FNLPFIDVMKVCA-------FRFVAR
GDSKLHLNHSRQHSCCKHISLQITPNVNGNDNPVIEQLSMVNTSHPL----RHISVNLKK
TTIWCSDGELIQRSSIICF----------------------------VHRKLLRFFGRGP
EHQNYNSDDDSMNSTSTEEKQESYRLLFQSLLDKNDSI
>gi|148228496|ref|NP_001086227.	Xenopus laevis
---------------------------MESAHSTSLAVL---------------------
---------CSVLSVKRQSCEVTLDPGRSLLSWRELRPRHGRERSRPGICLTRVLHQTRG
LVNRFTRQFPSGGVTVPVTEIVSVGEAEIDEKYYNSMKWQ--------------------
---HICKP------------------------------------------RAFTVRY---
--VQR-VRKH-RWRCKEVTFWCSDEQLFYQWLQ-----AFHDLLE------------QQT
HRP---KNLLVYINPYGGKKRGKQIYENKVAPLFSAAG-ICADVIVTEYANHARDHL-YD
A--NLEKYDGVVCVGGDGMFSEVLHGLIVRMQKDSDVDHNNP-SAQLSRCNMRIGIIPAG
STDCI---------CYATVGINDPETSALHIILGD-----CQPLDVCSVHYKRT----FL
KYSVSLLGYGFYGDVLKGSEKNRWL-GPARYDVSGFKTFLTH--HCYEGSVSFQPAK-WV
L----------GSPRDQTT-------CTSGCYICR-------------------------
------------------------------------------------------------
-------QSSKQLDEQEQTQAC------------------------GSEHR------E--
QDDDWTTIKGRFMAINAVSMSCACP--RSPNGLSPAAHLADGSADLILVR-KCSRLDFLR
HLIRHTSNKDQ-----------------------FDFPFVEVYRVKN-------FQFT--
-----------PKHFEDEDNESTDIGILGKKN-----FSQICTDHPS---CGC----NHV
NSIWNCDGETLDQTAIEMR----------------------------VHCQLIKLFARGI
ENAKLEDDVNPSKVF-----------------------
>gi|115911653|ref|XP_797972.2|	Strongylocentrotus purpuratus
--------------------MEHVNSTSSRNEESSSTDL---------------------
----QATFDI-------ERKSCDVRLSSQSITWWEASSTLGMHHQLH-------------
-----------NHQCIQLNRIVGVRLKGPEKPSSPDGNHMMTLSQMGQLF----------
---QVFTPSTHHPL------------------------------------FSFTVY----
--VGR-NSRQTKWKVQAVTFSSHDQELCMMWVD-----RIKTALQ------------QGH
GRP---KRLHVIVNPYGGKGKGQSVYDIKVAPLFHLAD-IETSMTITEGPDHAKSLM-QM
M--DLTGIDGIVSVGGDGTFADIVNGLLIRTQQEEGIDPNNP-ASVPVPLGLRVGIIPAG
STDVM---------AYDTTGVNDPVTSAIQIILGF-----SLALDVCSVHHNNS----LL
RYTVSFMGYGFLGDVLKESENYRWM-GPSRYEFAGVKKYLRN--HAYLGEVSFLPSK-DE
D----------NTPWDKKG-------CMIGCGVCS-------------------------
------------------------------------------------------------
-------KRKSRNRHDVYKKSD------------------------MIDSG------D--
SSSKWRHVRGRFTAINAALVSGRCS--RTVTGMSPAAHLGNGCLDLVLVR-QCSRFDYLR
HMLKLASSGNH-----------------------FNFDFVEVHRAKA-------FKFRSL
NTDLELAMVAEPSNVENE---QQTFGKGSPKR-----FGMYKAVRTG---SVC------S
TSSWNMDGEVGEPPDIDVSQ------------IHFVRNDELAEAWRIFTPVLHEIESKKP
KPIPYKYGGRGPAEADEMAKKNNFLFTGTYKWNNPNK-
>gi|91079356|ref|XP_970111.1|	Tribolium castaneum
------------------------METKSEESAQNRVLL---------------------
----EETFYVLTK----KNCVFRVRLTKAGLCLVKESENNIKEQ----------------
--------------VIPIQDIIGCRCLRSKKQSKNCACQSIPRSANLKVVEENSGDL---
---DDTDVSAYLYI------------------------------------YAYILVNNKG
TSKKR-ERTIITLRFRSFDKYEDNNKEAQRWRT-----MIKRLIKGENVSTSHIADFSVS
NKYKEDRRLLVLCNPKSGPGKGRIIFQQKVVPILQEAE-IPYDLHITKYANFAREFI-RT
C--NIFQWSGIILVGGDGIVFEAINGLFERWDWSDVVKT------------IPIGVIPGG
SGNGLARSIAYH--CSEPYLPSPTLPSALAAVRNN-----CAPMDLVRVETTSQ-----I
MFSFLSVGWGFLSDIDIESERLRML-GGQRFTVWSVARLIGL--RSYGGKLWYLPAN-VP
LVPTRLEV---NTGSALDLPAEVHLETQTGRQRLDSWYSAASRRSAYFSATGSSYQSTAD
SGGGG-------------------------------DPFGGDPDKPRMYGPASKLPCLTQ
PLDKGNFVVGCCLTCQVQHRVF------------------------RLNSTLEVLMINVI
IPETWKCIEGRFVMVHASYQTHLG----EDCLFAPDAKLNDGTIWLLIVHGGTTRTQLLH
FLLGLSTGAHTSMV--------------------GEGGPIELIAVNA-------FRIE--
-------------------------------------PDMNEQGYMT-------------
-----VDGEHVEYGPIQAE----------------------------VFPSLARVMVP--
--------------------------------------
>gi|16768660|gb|AAL28549.1|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MRV---RRLLVFINPYGGRKAGAQTYERHVRPIFQLAG-VDATCITTQRANQVKDIL-LS
H--DLGVYDAVCCVGGDGTVAEVINGLIFRQMRELGLDEQRP-P-YIPRPALPVGVIPAG
STDTI---------AYSMHGTADVRTAAIHVILGQ-----HRGLDVCSVSNGQS----LL
RFCASVLSYGYLGDVAAQSENYRWM-GPRRYEYSGVKAFLNN--RGYDAELRMLEEP-DL
LLTTPLEDIPQSPDSVCSLGESVPSVCYANCQRCS-------------------------
---------------------------FASSIQEQRSSLFIQEESKEAERNQQVETEDSH
LAASEAALLRPRPRPGNLRLPT------------------------GSISSMRNL-----
GNDQWKVVRGNFFMICGANITCACA--RSPNGISRYSHLGDGCLDLILVK-KTSLLNNVR
FLLNTAGRSGDI----------------------RNLPFVEVYRTRE-------FRFR--
----------TFSASEEDYSLAGSCQPIT--------PPEEMTAHSS----------STE
FSSWNCDGEVVTDLDITMR----------------------------SHCQLIEVFMRGP
HSYSKPLKGGTTPTTPASSSDNVYCCCKD---------
>gi|157020485|gb|EAA04298.3|	Anopheles gambiae
-------------------------MILAAAGSAATVYL---------------------
----TETFYISSK----KNTVFEVRLTDKGLCLKKQSNGATKEQ----------------
--------------TIPLKDIIGCRCLRSKRRSRGSSSCTCASISSSSQLKVVEENSGEQ
---DETDVSAYLYI------------------------------------YAYILKRSRR
G-GFR-ERTTITLRFRSFDRYEDNNREAQKWRA-----SIKQLVAGEPVQK------PVA
YQPRDTRKMLIILNPKSGSGKAREMFQQRVAPIFAEAE-IPYDLHITKKSNWAREFV-RV
R--DVYLWRGIVVVGGDGIFFEVLNGLFEREDWQTAIDE------------LPMGIIPCG
SGNGLAKTVSFL--YEEPFETKPVLASALMVVKGK-----HSMLDVVRVETRSN-----I
MFSFLSVGWGLISDIDIESERLRAI-GGQRFTVWSVHRLISL--RTYQGKVSYLPALVSP
VSGAGGEGLNGGGGGIGTLKHSVSYNTTLNCRDCR-----------AGLGGQDGTNGSCD
ACDTNFSDVLSLETGTNLDSFRPRIDSWYSA----------TSRKSTYFSTVDSVYESDK
ASNDDPTQCGPNGGTASHVQMY------------------------GPPSRLPALTAA--
IPDSWQTIAGEFVMVHAAYQTHLS----TECYFAPQSRLNDGIIWLLIIRAGVSRSQLLS
FLLGLSSGTHLPL---------------------QPNEYIQMVPVSA-------FRIE--
--------------------------------------PAGTNGHMT-------------
-----VDGEKVECGPIQGE----------------------------VFPSLGKVMVPK-
--------------------------------------
>gi|126338676|ref|XP_001375028.	Monodelphis domestica
-MTHVPPRGPQTTGESGPLPGTPPPVPALVAHARALPAREERDGDGGCETGERSAAGPGP
GADMEAEPGPPQLWLKRRRCFLSLDRPRALLAWGPCSDPVPDPSPDR-------------
-PPAPTPASGPGAYSVPVSEIITVEETEIDKKDHKSGKWQ--------------------
---KMAKP------------------------------------------YAFTVYY---
--VKR-SKKSCRWRCGHVTFWCTDEVLCNQWIQ-----TLRDLIK------------NLT
CRP---KHLLVYINPFGGKRQAKRVYEQKIVPLFNLAS-ITTDVIVTEHANHAKDSL-FE
I--NIEKYDGVVCVGGDGMFSEVLHGLIGRTQKDYGIDQNDP-KASLVQCNLRIGIIPAG
STDCV---------CYATIGINDPVTSALHIIIGD-----SLSMDVSSVHHSNT----FL
KYSVSLLGYGFYGDVLKDSEKKRWM-GLVRYDFSGLKTFLSH--HCYEGTVAFLPAQ-HT
V----------GSPRDKKP-------CRSGCFICR-------------------------
------------------------------------------------------------
-------QSKQQLEDEQKKSLY------------------------GLANT------E--
EVEEWKMIHGKFLAINATNMSCACP--RSPKGLSPMAHLADGSLDLILVR-KCSRLNFLR
YLVRHTNEDDQ-----------------------FDFTFVEVYRVRK-------FQFM--
-----------SRHSEEE---DGDLKDLRKKH-----FGSICSNHQA---CCC----SLP
NSTWNCDGEILDNSAIEVR----------------------------VHCQLVQLFARGI
EETPKQEALS----------------------------
>gi|50311939|ref|XP_456001.1|	Kluyveromyces lactis
MSKLSRKYHLPYTRAIIGENGLLIKDQFTSGPSTSSSTLLARRSNGGDFGDDED------
----DEDGDASGSFQSSVFETASLISCVTCLSDTESKDENEALLLPS-------------
------------NTVIPYAKILDVTNMEAEDDGSPWPDHT--------------------
---ALIE-------------------------------------------VTFAKPR---
--RNHLVPKTIKLSVDTSVFPNMGTDVAEEILN---------------------RSYKNT
KRN---KSILVIINPHGGKGKANKLFLSKAKPILLASG-CKIVVKETTYHLHAVDIA-KN
L--DIDEYDVVACASGDGIPHEIMNGLFLRSDRAKAFQK------------LAITQLPCG
SGNAM---------SISCHGTSNPSYAALALLKSV-----ESRIDVMCCTQPSYKN--QP
RLSFLSQTYGIIAESDIDTEFIRFI-GPARFELGVTMNVLQR--KKYPCDIYFKYAA---
-----------KTKNELKDHYLQHKDRLNNLRNDL-------------------------
-------------------------------------------------ESSSTFTLDIP
RSGKESNLDDITITDDSFKLRW------------------------PFEDD---------
VPSDWERIDPELTRNTGIFYTGKMPYIAPDTKFFPAALPDDGTMDFVLTDGRTPLTRIAP
ILMSLNRGSH------------------------VLQPEVEHSKILA-------FRLV--
--------------------------------------PYAKNSVIS-------------
-----VDGENFPYETLQVE----------------------------VLPKLVKTLLKNG
SYVETDFESM----------------------------
>gi|157106619|ref|XP_001649407.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------KWRVQQLVLYKNEHRIVKLWYQ-----RLSEDIR-------------EQ
NRP---KNLLLFLNPYGGKQKAFALFEKYAKPLFKLAQ-VDINLIITQRAQQIYDIM-TS
QTINLNNYDGVVCCGGDGTFAELFNGLVYRTMIDLGMDINQP-P-YLPKPSTPIGIIPAG
STDTV---------AYCLNGTTDIKTSILHIILGQ-----THGLDISSVYRNTERRPQLL
KLYASVLSYGFLGDVTLESENYRWM-GPKRYDYSGAKKFFRN--RGYSGDITIHVEN-EV
IDDERVER---NNPHDGVR-------CLENCQRCL-------------------------
------------------------------------------------------------
---DASAKSGNPIDCDTQK-----------------------------------------
-----VTVSGKFLMVNGANISCACS--RSPQGFNPYCHLGDGYLDLILVR-HTSFFNNIR
LLLAMSSKTKKI----------------------SDLPFVEIYRTKK-------FSFKGR
VVGAYQGHGHDNGAIDDELDQTGTTSASSASTNDIA-NSTVTAGRTA---TGSLKEDNKL
LSKWNCDGEILMDTNIIVE----------------------------CNCQLINVFRRGV
SCSDTSSKENDPGVLNCCGVCK----------------
>gi|149641719|ref|XP_001506327.	Ornithorhynchus anatinus
---------------------------------MPVRMK---------------------
----RRNSGIRVQKSASRPRGPAPGVNSPSPSDVCDDSRRGRYRLRG-------------
-------------YSVPVSEIIAVEETEIDEKRHNSGKWQ--------------------
---KMAKP------------------------------------------HAFTVYY---
--VKR-ARHH-HWRCGRVTFWCSEEQLCNRWLQ-----ALRESLE------------KLT
TRP---KHLLVYINPFGGKQQAKRIYEQKVAPLFSLAS-VSADVIVTEHANHAKDSL-LE
I--NIEKYDGIVCVGGDGMFSEVMHGLIGRTQKDSGIDQNNP-RASLVRCNLRIGIIPAG
STDCV---------CYATVGTNDPVTSALHIIVGD-----SLPLDVSSVHHDDT----FL
KYSVSLLGYGFYGDILRDSEKKRWM-GLIRYDFSGLKTFLSH--HYYEGTVSFLPAQ-HA
V----------GSPRDKKG-------CHTGCFVCR-------------------------
------------------------------------------------------------
-------QSKQQLEEQQKKALY------------------------GLENT------E--
EAEEWKVVRGKFLAINAANMSCACP--RSRKGLSPAAHLADGSADLILVR-KCSRFNFLR
YLLRHTNRDDQ-----------------------FDFTFVEVYRVRK-------FRFA--
-----------SKHSEEE---DAAGRPGGPKP-----PGPACGDHPA--PCCCGRCGPLG
GSTWNCDGEILNSSAIEVR----------------------------VHCQLLRLFARGI
EEKPRREERS----------------------------
>gi|8248285|gb|AAF74124.1|	Homo sapiens
------------------------MAPPPPPLAASTPLL---------------------
----HGEFGSYPA----RGPRFALTLTSQALHIQRLRPKPEARPRGG-------------
--------------LVPLAEVSGCCTLRSR------------------------------
---SPSDSAAYFCI------------------------------------YTYPRGRR--
--GAR-RRATRTFRADGAATYEENRAEAQRWAT-----ALTCLLRGLPLPGDGEITPDLL
PRP---PRLLLLVNPFGGRGLAWQWCKNHVLPMISEAG-LSFNLIQTERQNHARELV-QG
L--SLSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVK-------------MPVGILPCG
SGNALAGAVNQHGGFEPALGLDLLLNCSLLLCRGG-----GHPLDLLSVTLASG----SR
CFSFLSVAWGFVSDVDIQSERFRAL-GSARFTLGTVLGLATL--HTYRGRLSYLPATVEP
ASPTPAH----SLPRAKSE-------LTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALAS
PGSPEPLPILSLNGGG-----PELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEG
APVIPPSSGLPLPTPDARVGAS---------------------TCGPPDHLLPPLGTP--
LPPDWVTLEGDFVLMLAISPSHLG----ADLVAAPHARFDDGLVHLCWVRSGISRAALLR
LFLAMERGSHFS----------------------LGCPQLGYAAARA-------FRLE--
--------------------------------------PLTPRGVLT-------------
-----VDGEQVEYGPLQAQ----------------------------MHPGIGTLLTGPP
GCPGREP-------------------------------
>gi|58865706|ref|NP_001012066.1	Rattus norvegicus
-----------------------MAPPPLLPVAASTPIL---------------------
----HGEFGSYPA----HGPRFALTLTTQALHIQRLRPKPEARPRDG-------------
--------------LVPLDEVSGCGTLQSR------------------------------
---SPEDTAAYFCI------------------------------------YTYPRGRR--
--GGR-RRATRTFRADGAATYVENRAEAQRWAT-----ALMCLLRGVPLSGDQEITPELL
PRK---PRLLLLVNPFGGRGLAWQRCMDHVVPMISEAG-LSFNLIQTERQNHARELV-QG
L--SLSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAVR-------------MPIGVLPCG
SGNALAGAVNHHGGFEQTVGVDLLLNCSLLLCRGG-----SHPLDLLSVTLASG----SR
CFSFLSVAWGFLSDVDIHSERFRAL-GSARFTLGAVLGLATL--HTYRGRLSYLPATTEP
ALPIPGH----GLPRAKSE-------LALAPAPAPAATHSPLHRSVSDLPLPLPQPALAS
PGSPEPLPDLSLNGGG-----PELTGDWGGAGDAPLSPDPLLPSSPNAFKTAQLSPIAEG
PSEMPASGLLPPIHNAPEASTW-----------------------GPADHLLPPLGSP--
LPQDWVTIEGEFVLMLAILPSHLC----ADLMAAPHARFDDGVVHLCWVRSGISRAALLR
ILLAMEHGNHFS----------------------LGCPHLGYAAARA-------FRLE--
--------------------------------------PLTPRGVLT-------------
-----VDGELVEYGPIQAQ----------------------------VHPSLATLLTGPA
GQKPRA--------------------------------
>gi|45201352|ref|NP_986922.1|	Ashbya gossypii
----MLGLYKYTKSYSRAILGSAGVVVKEQGSGNSAQAA---------------------
----EGALDDSDSQSSAMLETASLISCVTCLSDNMDSHSTDPLLLQS-------------
------------NTVIPYAKILNARLALEAPAEGGADDSFTEGARSVQDAEISSKPGSSS
SRARAEGGMKSGGV------------------------------------LVDIVFA---
--KPR-RNDLVPKTVTLFVEYSSDDFYGGGEAD-----VVEEILR---------RSYMNT
KRN---KSILVIINPYGGKGKAHKLYVTKAKPILVASD-CQIDVVETKYSSHAAEIA-AT
M--DINKYDVIACASGDGIPHEVLNGLFTRPDRVAAFNK------------LAITQLPCG
SGNAM---------SISCHGTSNPSYASLSLVKAT-----EARVDLMCCTQPSYAS--SP
RVSFLSQTYGVIAESDINTEFMRWI-GPARFELGVTLNIFQR--RKYPCQLYVKYAA---
-----------KTKNELREHFTLHKARITQSFRSE-------------------------
------------------------------------------------------LMDSGS
HLADLPSTDSDLIDDSCFHLKW------------------------SLDEP---------
VPQDWEEIDTSLTDNLGIFYVGKMPYIAPDTKFFPAALHDDGAMDMVITDARTPLTRIAP
ILLSLDKGSH------------------------VLQPEVEHSKIEA-------YRLI--
--------------------------------------PKLKSSIIS-------------
-----VDGENFPFEPIQVE----------------------------VLPRLAKTLLKNG
CYVETEFEAL----------------------------
>gi|125981739|ref|XP_001354873.	Drosophila pseudoobscura
---------------------PSLPSTPTSASSETSQAL---------------------
----SEIFFVESSRRK-HSIKIQVKLCPEGVYLRRETDQDDHINEQ--------------
--------------LIRIDDIIGSRFGPRLKKRPRGGLNSCKNPSGDATQEQEQQ-----
---PDRDNSAYLYI------------------------------------YAYLKKEKP-
--LRR-VQTLRILRFRSSNDYAENLQTAELWHR-----TIREHKQRNSTTIDTNGSVLGA
GSV---KHLLILLNPKSGSGKGRELFQKQVAPLLTEAE-VQYDLQITTHPHYAKEFV-RT
RKDLLERYSGIVVASGDGLFYEVLNGLMERMDWRRACRN------------LPLGIIPCG
SGNGLAKSVAHH--CNEPYEPKPILHATLTCIAGR-----STPMDVVRVELSSRDKH-YV
MYSFLSVGWGLIADIDIESERLRSI-GAQRFTLWAIKRLISL--RSYKGKEKETPRQ-LP
VEEQAPPSRPVSLPLNVNGDVSEESEFRDLPEDLN-------------------------
---------------------------EESETDTDQFADALSMDRSIFRQHADSWHSAMS
RRTAYYSVGGQSIRSNRSRMSV----------SQRIEAANAEFAELVPSGTIPGLQLPLP
AADGWCCEEGEFVMVHAAYTTHLS----SDCYFAPESRLNDGIIYLVIIRSGVGRHQMLN
FLLSMNTGTHLPPG--------------------DDDPFIRVVPVKA-------FRIE--
--------------------------------------PSASDGILV-------------
-----VDGERVDYGPIQAE----------------------------VLPGLINVMTTNG
Q-------------------------------------
