>gi|118090579|ref|XP_420734.2|	Gallus gallus
------------------------------------------------------------
------------------------------------MPLLFPSVF---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------LQQ
VTGRSFGEKDFRSGLENGILLCEL--LNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKE
LGLKESQLFDPGDLQDTS-NRVTVKNVDCSRKLKNVLVTIYWLGKAANSCTSYSGSTLNL
KEFEGLLAQ-MRKETEDIE----SPKRSIRDSGYIDCWDSE-------RSD--SLSPPR-
HGRDDSFDSLDSFGSRSQQTPSPDVVL-RGSSDGRGSDS---ETD-LPHRK---------
---------M--------------------------------------------------
-------------------------P-DVKKDDMLARRTSHGEPKSAVPFNQYLPNK---
SNQTFYV------------------------PAPLRKKK-------AE----REE-YRKS
WSTAT-SPL-GDRP----------------------------------------------
---FRFGPRTAVSDD------------------------------------AE-------
-------------------------------------------------SVSMFDMRSEE
EA-MAQPHSKARHEKLQN--IHNQLKEDETRWQDDLARWKSRRRSASQDLIKKEAER---
KKMERLLSGE-GTNERR----------KSIKTYREIV-----EEKERRERELHEAYKNAK
TQEEAESILQQYIERFTI---SEAVLERLQMPKILE-RSHSVEPNSP--L----------
---KD-------------------------------------------------------
---------P--------------N-PLRYLRQQSLPAPKFTATIEATIVP----TTELE
PSGSTGRTSP--SKSVVSKAVPMLTPKPY--SQPKNTQEVLKNFKVDGKVSMNGE-----
---NFNGVEE-KDKECTTVI-FTQSPSRSLKFDGVARGDGPPIELKKDPTSVELSLQRPA
TQN--------VPGDTA-GTAHGCEPSFQVGKSLHSSTELNNLEFHLASSEQKQ------
---------FKSTVLCASPV----------------VKSLEFSPSPVPPEETAPSEKDVK
KPEMEKQKEA--------------------------------ALP-AMQEVMK-PKALEQ
EGSVVLPFL--------------------------KKLPETSQVT------LHNSDLQAD
SG----------------------NSDKSNVSTFFCIVRFNFWSWDPEEE---RKRQERW
QHEQERLLQEKYQKEQDKLK-----EEWEKAQREVEEEERRYYEEER--KIIEDTVVPFI
VSSNSAELLSSSSSTTEGNKTANTSDSNGSPEEGKPKEVTRQKKLVWE--QDSIASLKNK
ENERWQEKRRYGPRGAFF----------LSGHPE--------------------------
-------------------------------------------------------VGILK
GGDQEYQVPVMERCS-----------------P-ARLNLPLTQDVP--WNQQLLTKQSPH
HAEDARQRPL-LGQSAGQQPSAAGEGRR--------------------AGCHENFRS---
------------------------GPSSPCSPAAPSQSP----------NRSVSGKKLCS
TCGLPLGKGAAMIIETLGLYFHIQCFRCGICKGQLG-DAASGTDVRIRN-------GLLN
CNDCYIRSRTAGQPTTL--
>gi|24644057|ref|NP_649488.2|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
DKAQHPQKREQKEELGG-------------KPEEKEPI-------------------CEE
QHDEESN-----EQGETH-NEGGEMPNKTDKQMQGGREPIY----------ENVSSTISM
HEVDNEQIATMTITTQTQATR-ISHRRSIPSQQTSNSNENN-------QST--NQTSNSR
NQKESSTAATSAANPVPPTTPGEQAE--PYYQVPKATEP---YYDAPKHLRP--------
---------V--------------------------------------------------
-------------------------P-VYENVEIFYSGLEISQGSVGAPVGLMEP-----
-------------------------------P----KEK-------PP------------
-------PPPTESP----------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----IPLDEGHDDELDG--LGNSLGHNTDTWSSD-------------------------
------------------------------NTYETIS-----NGTRR-------------
--------HLQGQPEPAQ---PSPPIKRMNSTKRIK-KELRNKRSSFLGI----------
ENDGD-------------------------------------------------------
---------L--------------DDMETYLELTVAPPPDMAQLLQEERRL------EKQ
LYIKAGLCDS--SDTGESRDS---------GVSENHSRQSSEHYTNSSE---END-----
---TQSEATPPPLPPPPSTAQVGEVIYQNESLLAAQTPLLQTVKGNSAESWTESATAAAA
ATQ--------SLSEATATANAKMQSIEDKIREQGEMLRVERELLHFSQEELKR------
--------------QRENLV----------------LRENIARRELQHGAKMLMSNNRRS
LQDLHHGLGI--------------------------------GNG-MLSAFQP-PQHHQV
QMPPPHPQQ--------------------------IYANVPQQQQQMVLHAYHQMDTDYR
KS----------------------MSDLNEFSNCLILP---------------------P
TPPTKPLRAMQLNANGHGLE-----PDYAVSTRQRQPPA-PYGGSLV--KIAGAPMPPRL
PGQGYPIQ----------APTAPAYHHQSAQNLSNM----SRNTLLA---LSATPKPKYA
--DGWVQV--QQRKSYDSQQTSDAAWLAAQQQKR--------------------------
-------------------------------------------------------KSMPD
YGGALYNNNHWLLQE-----------------AEQRRIEQLN------------RRSIPA
SKSMGKPLPDSIIQTLTERVQSKGIGDR------------------------KRFDSNGN
YSQVNGNNIYQQQ----QQQKNVTNGSSINGNSSQGQEK----------VLSVSGKKKCS
HCGDELGRGAAMIIESLLLFYHINCFKCCVCHVQLG-DGLNGTDVRVRN-------HKLH
CQNCYSSDDG-IKFSCV--
>gi|46811858|gb|AAT02181.1|	Rattus norvegicus
------------------------------------------------------------
------------------------------------MEGMEDAEA-------DCSIAFAE
AQR-------------------W-------------------------------------
------------------------------------------------------------
---------------------------------------------------------VEA
VTEKNFETRDFRASLENGVLLCDL--INKLKPGVVRKINRLSTPIAGLDNINVFLKACEQ
IGLKEAQLFHPGDLQDLS-NRVTVKQEETDRRLKNVLITLYWLGRKAQNNPYYHGPYLNL
KAFETLLGQALTKALEDSS----CLKRSGRDSGYGDIWCPD-------RGD--FPAPPGS
HRREDSFESLDSLGSRSLTSCSSDLTL-RGGREGCESDN---DWE-FTFK----------
---------M--------------------------------------------------
-------------------------Q-DYNKDDMSYRRISAIEPKSALPFNRFLPNK---
SKQPSYV------------------------PAPLRKKR-------PD----KNEDNRRS
WASPVYTETEGTFS----------------------------------------------
----RLFQKIYGENG---------------------------------------------
-------------------------------------------------SKSLSDVSAE-
---DVQSLRQLRYEEMQK--IKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER---
EEIEKQ-----ALEKSD----------RSSKTFREML-----QDRES----QSSTTTSRR
RIYSSDDILDDGVLPPTV-----TLSETSYQSERLE-DKARAHPAEMPKEDSTTFASRED
GIAAEIPLASHIPEERRQAPWPSAETRQASSSSAESHQASLPSTESDQARLPSAEPHQAS
FSSAEPRQVPLVSAEPHQASSFSSTEPHQASLSSALQRPSSLSSSQQSWST---RGESTR
ISASLPRSY---QRSDTARLTSVVTARPF-GTSSRGISSLPRSYTMDDGWIYNGDVEVVK
REQHDSGRAAGMKPDSSHFILGSSSEKEVATGEDGASLSSFVLPSSSSLSHDQAASSKAT
FSS--------TSGLDSVSDSGEGRSSSL-REVSRSPDQFSDMRISINQTPGTKHDFGFT
IKWDVSGI-SVASVEKGSPAEFSQLQVDDEILAINNTKFSYKDTKKWEEAMANAQETGNL
VMDVRRYGKS---------------------------GSPETKWI-DTTSGIY-STEKSS
SLSVTTDFS--------------------------ESLQSPYSESKEING-IHEGSNAFD
SKASESISLKNLKRRSQFFEQGSSDSVAPDLPVPTLSA-PSRWAWDQEEE---RRRQERW
QKEQDRLLQEKYQREQEKLR-----EEWQRAQQEAERENSKYLDEEL--MVLNSNSISLT
SRESVTASWEPSW-----SEGSKSLDREGTRAGDEDRGQLEDDAVYEDQSQKLQERLMLE
HEKKRKEQEAQEEELRKQREAEAQARAEAEAQARAEAQARAEAQAQAEAEARKRAEAQKL
QAERERETSVKIYQYRRPIDSYDLPKREEESSGLLPIDRSKSRSTTELNDPLIEKSGSSK
YSDRIGTTSFSQRSSKKDQGPSEAELERQQILQEMRKKTSLHNDNS--WIRQ--RSASVN
KEPICLTGIMRRGESLDNLDSQRPGSWRQSSWHSQPAGVYASSSVQDFSRLPPQLLSTSN
RAYMRNPSSAVPP-------LAGSVKTSPGSPSPRSHSPSMSQSGSQLRNRSVSGKRVCS
YCNSILGKGAAMIIETLGLCYHLHCFKCVSCERDLG-GSSSGAEVRIRN-------HQLY
CNDCYLRFKS-GRPTAM--
>gi|126331801|ref|XP_001373353.	Monodelphis domestica
MAPGLCVKEESEEEKVDKTRLVVCDIELVMAQTNGFEQRLSWLQDSTLMREGGLEKELIV
TAAGNEGNSRLSFLLHRTIQPVTGVTGKTAWRGWGKAGRSSPCPADTGGHCRFFPVSLAK
ATRSRSTLARLGVRPSPPRCPASPAVLPRPCPSWYRAGGGGGGGGGGARVGGERELRRCL
PAGTPLTPAEHCRRWERPLQQRVPSHPFPQAAPAPLPGLPGRCWQTAGGGGGGGGGGGGG
GREAGSGTTPAPILPSLAAAESAEDRERLQMASLGLGLEELQPDPPPEPAFHEAQKWIEQ
VTGRSFGDRDFRTGLENGILLCEL--LNSIKPGLIKKINRLPTPIAGLDNIILFLRGCKE
LGLKESQLFDPGDLQDTS-NRVTVKSIDYSRKLKNVLVTIYWLGKAANSCTAFSGTPLNL
KEFEGLLAQ-MRKETDDIE----SPKRSIRDSGYIDCWDSE-------RSD--SLSPPR-
HGRDDSFDSLDSFGSRSQQTPSPDVVL-RGSSDGRGSDS---ESD-LPHRK---------
---------L--------------------------------------------------
-------------------------P-DVKKDDMSARRTSHGEPKSAVPFNQYLPNK---
SNQTAYI------------------------PAPLRRKK-------TE----REE-YRKS
WSTAT-SPLGGERT----------------------------------------------
---FRYGPRTAVSDD------------------------------------AE-------
-------------------------------------------------SMSMLDMRCEE
EA-TVQPHSKARQEQLQF--INSQLKEEDDKWQDDLARWKSRRRSASQDLIKKEAER---
KKMERLLAGGDGTSERR----------KSIKTYREIV-----QEKERRERELHEAYKNAR
SREEAEGILQQYIERFTI---SEAVLERLEMPKILE-RSHSTEPNSSSL-----------
---ND-------------------------------------------------------
---------P--------------N-PMKYLRQQSLPPPKFTATVETTIAC----PSEPD
PNVSAGSASP--SKTVVPKAVPMLTPKPY--SQPKNTQHVLKTFKVDEKVSVNGE-----
---TFNGVEEEKERECTTAT-FSPSLTRSQRFEGVARVDGSSVELKQDTSSIEISIKKAN
SLN----------RELTTSTTEEAELTPQQDEIDCGQEEGRNTG--CASPECQH------
---------FTTTVTRANPT----------------VAFVELNPSQ-QPKDHGAEDKDQR
KLESEMSGKV--------------------------------ELV-LSQKATK-PKSPEP
KAVLLFPYL--------------------------NPVPETNPST------LPNLDSQVE
SS----------------------STEKSPASTPR----SNFWAWDPEEE---RRRQEKW
QLEQERLLQERYQKEQDKLK-----EEWEKAQKEVEEEERRYYEEER--KIIEDTVVPFT
ISSSSADQLSTSSSVTEGNGPVNKMESEDSKEEEK-----RQRQLLEE--ENNDLLLKNS
KTDVLEETKSGSQV--------------TPAHPE--------------------------
-------------------------------------------------------NCVPK
GIHQDYQLSAAELGT-----------------PDRRLNLQLSQDTS--WNQPW-SPASSH
ALEDTKQKTLPIDQSINHQAASPSERRK--------------------ISPHENFRA---
------------------------GQLSPCSPTPPGQSP----------SRSISGKKLCS
ACGLPLGKGAAMIIETLSLYFHIQCFRCGICKGQLG-DSVSGTDVRIRN-------GLLN
CNDCYIRSRSAGQPTTL--
>gi|91095071|ref|XP_972774.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MSNNETSSSETSDKPFTICQI-------EEIKKERKEVREEAEDWQQNLDNWKSCRR
-KRQEHIIERVVEVKKME-QEEQERNRKKSKTFSEMMEDRS-KGRHKFNIPIYDDDSNDL
SDYGIGSSSSKTNSIKDVDTDDSCSILDEKENRSFESPCNK-------DNS--SASNQS-
QSEDETNSTKKDHARLSSNNVIKQTSL-YTSTKTNDNKT---ETT-EQYTYEGAIQDYRT
RIRSRIFVDE--------------------------------------------------
-------------------------S-IFTKTQDYSKSKEFSEAQTALPKGEIFKRK---
EIFEMEK------------------------PLEINNYE-------SP--------TARR
LSEDF-VNTQSIKQ----------------------------------------------
----RLKSLEKCTEQ---------------------------------------------
-------------------------------------------------SLTNDSVKQRL
HNDDTKNNNKARPAKISNYLIDKSSLETKNNINAEWKKKETERCSSPETELYMDNLKTFS
RDLDTLMYGKSGNNIDDYCVNPNYPPSTSSTELMGIS-----SDRED--SGIHTADVSCS
VSQADEPVEDNELAATTI----PSCIEKLTIDKRNEFDEIPASQNELNYV-----TTTQL
EIGNK-------------------------------------------------------
---------PETNKTDMKQVVESTLTLLESLQRDSSENQSAEKSVPCKPQQNVTPVEFID
EIVIDGAFPLAPPKMIEPPKVKPPPPPPV-DEDPVEMKRLNSTKRIKREMHIKRS-----
---SFLGLDEPTDDQIYPEVTVDKPPDISSFLQKESKLEKQLYKKTQEENRMGILSKVES
HDSGLDIDRGRLSSDTWCSSIGDSTTPSPERHDSEQTNSITSEEDEITKKEREIIEMVEK
EEKSRDGVEYLSPSEKQNQVILRNNQLNEPYLGSESFNNPYFPKEPSNYLDDQDSEVLKV
EHELRQLEREE--------------------------LKRQHENM-LFQESRA-KARLNN
RHSSENIFD--------------------------DMYYQDGVNYRKSMPELQHVPLEYR
KS-------------------------LPDVPNA-----YSVYRPVPELDVQYRKSMPDI
QHAYHKSVPEYHKSVSENLDHRKSMPDIQRSAFKSPPPVKKQ-------PIMPGKPIRPM
SKEQRDRYLMMNPTMTDSGGKPRQLSRHSLQA------------------LSAVPKNRHL
PVDNWIQ-------------------------PR--------------------------
-------------------------------------------------------QNVDK
NAKQHWLIQE----------------------AELRRISEQKNAASRNWQQPRQEKHLPD
SVIQTLTQRAQNRAEINDRNQPVRRSET--------------------SPSKDGMQH---
--------------------------PYLGHALPMPYPPPIAMEETQDRRLSVSGKKKCS
NCNKELGRGAAMIIESLCLFYHMECFICCVCHMQLG-DGRMGTDVRVRN-------QKLH
CHNCYSSDDG-IKFSCV--
>gi|125803994|ref|XP_693186.2|	Danio rerio
------------------------------------------------------------
------------------------------------MEWRQQSSV-------SCELAFQE
AQR-------------------W-------------------------------------
------------------------------------------------------------
---------------------------------------------------------IEE
VTKKSFGSKSFRVALEDGVLLCDL--INTLKPGIIKRLNRLSTPIAGLDNVNVFLKACKK
LGLNEAQLFHPGDLQDVS-TRVTVRREETNRRLKNVLITIYWLGRKAQSDPFYTGPQLNL
KAFEGLLGIALSKALEELA----QSRLSVRDSGYSEGWFSD-------REELYSVKQPS-
YRREDSVESLDSVESRAL-SVASDLTL-RAGSEGCCSDA---EAE-HFFR----------
---------MAESSKSGAPIREKAHVPAVLRKKRQDYQQGSRSYAGHLTSESGHGLCHDL
PPASAFLQWASSYQSDSDSDSDRPEA-DPEQDDLASRRFRSVTSAA--PVNFAIPSKPQG
PRVTAYVTPNAGKSWLTLSDATRSNQSLSSIPSENGRTD-------SDSANLEEEFLQRV
LSNGT-SDSDEDRG----------------------YADPVLDDLYARRVLVSEHQTSIN
ANSDKFLPKFWTPEEDLHVRKIRLGSQRRPWYKKMQGLRSKSMGDITLEPIPQESDNSSS
FDSLG--------------------------------------------PLHVHQRSDEE
LSLDPSALQRVQYEQLQH--IRQRMKENEAKWHEDLSRWKSRRRSANSDLHKKLEER---
EQIELITTAGGASGIRT----------AHLTGVPEES-----SSMPGPMSDAGSSVSSSG
WSTSASGLANGATSALTR----GTVVETSDSAQKCT-GVLSSHPSAVVSE----------
---QT-------------------------------------------------------
---------S--------------QSSLTAVDAESDEQQGPDFSLRSSLLE-SFYAGGAR
MSATLPRGFR--RSEGCSRLSTGVTPRPF-GAKPSKMPTLPKVYSVDDS-----------
---HKSLISGHRDHSAVPSFLGGQGKVTASAGKGHSRSSTHPINPKEEETRDGRSSAPPM
NSY---------ATKVTMTTSIIQTSPPAISEIRDVKVGQSEMRVCLNQKPNSGRDFGFK
AHWDSVGA-YVKSVQAGSPAELYGLLMGDEIVALGGRRVDEMNYEQFKSSMETAQQNGTL
LMDIRRHGQN--------------------------------DWG-SGQPSLPYQSHKII
NLTSATSTLIGRPEHFVPINTSSNSSVETVGKTQVNGQPANGVLSKMMNGSIQDNAAAVR
NK-------------------GGSESDISDLQVPSISTTSSSWSWDHEEE---RRRQEKW
QMEQERLLQEKYRRDQEKLE-----EEWRRAQQEVYGEEYCGLEEQKTLDVLSNGNPAPH
NSPPFYNQSSATFSVTFNENVAAAQNRQACVQTAAG----HQSIKAEDKCDSPTKTLCSE
ESYGFAKLT-------------------VSDRTK--------------------------
-------------------------------------------------------SKSTP
ALEALHKQDAKEGCSKKKGQLSQAEKERLQILDEMRKKTPLHTDSS--WIRQ--RNASIN
KETITVGTSIRRYESMDNLHTTNSWSRQ-------------SYTSGLSSRPHSALGSSGS
YRSGRSS----LGPGSAIFSTGVKLNSNTTTPEPPGLES---RPNSQQQGRLVSGRRMCS
RCEQPLGKGAAMVIDSLELCFHIGCFKCVSCRTELGRGPESGAQSVPQSPSDQNALQQIE
EEERTTETAT-GIATINTT
>gi|134053896|ref|NP_001001980.	Mus musculus
------------------------------------------------------------
----------------------------------MACPALGLEVLQPLQPEPPPEPAFAE
AQK-------------------W-------------------------------------
------------------------------------------------------------
---------------------------------------------------------IEQ
VTGRSFGDKDFRTGLENGILLCEL--LNAIKPGLVKKINRLPTPIAGLDNTILFLRGCKE
LGLKESQLFDPSDLQDTS-NRVTVKNLDYSRKLKNVLVTIYWLGKAANSCASYGGTTLNL
KEFEGLLAQ-MRKETDDID----SPKRSIRDSGYIDCWDSE-------RSD--SLSPPR-
HGRDDSFDSLDSFGSRSRQTPSPDVVL-RGSSDGRGSDS---ESD-LPHRK---------
---------L--------------------------------------------------
-------------------------P-DVKKDDMSARRTSHGEPKSAVPFNQYLPNK---
SNQTAYV------------------------PAPLRKKK-------AE----REE-FRKS
WSTAT-SPLGGERP----------------------------------------------
---FRYGPRTPVSDD------------------------------------AE-------
-------------------------------------------------STSMFDMRCEE
EA-AVLPHSRARQEQLQL--INNQLREEDDKWQDDLARWKSRRRSASQDLIKKEEER---
KKMEKLMSGEDGTSERR----------KSIKTYREIV-----QEKERRERELHEAYKNAR
SQEEAEGILQQYIERFTI---SEAVLERLEMPKILE-RSHSTEPNVSSFP----------
---ND-------------------------------------------------------
---------P---------------SPMKYLRQQSLPPPKFTATVETTIAR----TSVPE
SIASAGTGSP--SKIITPNTVPMLTPRPY--SQPKNSQEVLKTFKVDGKVSMNGE-----
---MAPGDEEGKEKEGPAAAAPGPSLTKSQMFEGVATVHDSPVQVKQGSNSIEINIKKPN
SAP-----------QELTAASEETESNGQEDEDGEERPGTGDLE--PDSAEPQH------
---------FTTTVTRCSPT----------------VALVEFSSNP--QLKNEVPEQGQK
KPEDEMSGKV--------------------------------ELV-LSQKVAK-PKSPEP
EATLTFPFL--------------------------DKMPETNQLH------LPNPSSQAD
SP----------------------SSEKSPGSTP-----FKFWAWDPEEE---RRRQEKW
QQEQERLLQERYQKEQDKLK-----EEWEKAQKEVEEEERRYYEEER--KIIEDTVVPFT
ISSSSADQLSTSLSVTEGSGTRNKMDLENCPDKENER---RQKTPFQ---ENDGDSLLKT
REGGLPEEQSLTPS--------------PSANPE--------------------------
-------------------------------------------------------ISVSK
GIHQDPQLEA-EAGA-----------------PHCGTNPQPAQDPP--RNQQI-PNPPTS
TSEDVKPKTLALEKTINHQMESPGERRK--------------------------------
---------------------------------------------------SISGKKLCS
SCGLTLGKGAAMIIETLNLYFHIQCFRCGICKGQLG-DAVSGTDVRIRN-------GLLN
CTDCYMRSRSAGQPTTL--
>gi|114650089|ref|XP_001139492.	Pan troglodytes
------------------------------------------------------------
------------------------------------MKKIRICHIFTFYSWMSYDVLFQR
TELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDIILRTEQNSGRTI------------
------------------------------------------------------------
--------------------------------------------------------LIKA
VTEKNFETKDFRASLENGVLLCDL--INKLKPGVIKKINRLSTPIAGLDNINVFLKACEQ
IGLKEAQLFHPGDLQDLS-NRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL
KAFENLLGQALTKALEDSS----FLKRSGRDSGYGDIWCPE-------RGE--FLAPPRH
HKREDSFESLDSLGSRSLTSCSSDITL-RGGREGFESDT---DSE-FTFK----------
---------M--------------------------------------------------
-------------------------Q-DYNKDDMSYRRISAVEPKTALPFNRFLPNK---
SRQPSYV------------------------PAPLRKKK-------PD----KHEDNRRS
WASPVYTEADGTFS----------------------------------------------
----RLFQKIYGENG---------------------------------------------
-------------------------------------------------SKSMSDVSAE-
---DVQNLRQLRYEEMQK--IKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER---
EEIEKQ-----ALEKSE----------RSSKTFKEML-----QDRES--QNQKSTVPSRR
RMYSFDDVLEEGKRPPTM-----TVSEASYQSERVE-EKGATYPSEIPKEDSTTFAKRED
RVTTE-------------------------------------------------------
---------I--------------QLPSQSPVEE--QSPASLSSLRSRSTQ----MESTR
VSASLPRSY---QKTDTVRLTSVVTPRPF-GSQTRGISSLPRSYTMDDAWKYNGDVEDIK
RTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKAT
LSS--------TSGLDLMSESGEGEISPQ-REVSRSQDQFSDMRISINQTPGKSLDFGFT
IKWDIPGI-FVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHL
VMDVRRYGKA---------------------------GSPETKWI-DATSGIY-NSEKSS
NLSVTTDFS--------------------------ESLQSSNIESKEING-IHDESNAFE
SKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISA-PSRWVWDQEEE---RKRQERW
QKEQDRLLQEKYQREQEKLR-----EEWQRAKQEAERENSKYLDEEL--MVLSSNSMSLT
TREPSLATWEATW-----SEGSKSSDREGTRAGEEERRQPQEEVVREDQGKKPQDQLVIQ
RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKR--------------------------
QAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNK
YLDQIGNTTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNS--WIRQ--RSASVN
KEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSN
RAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICS
YCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLG-GSSSGAEVRIRN-------HQLY
CNDCYLRFKS-GRPTAM--
>gi|119600956|gb|EAW80550.1|	Homo sapiens
------------------------------------------------------------
------------------------------------MKKIRICHIFTFYSWMSYDVLFQR
TELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDIILRTEQNSGRTI------------
------------------------------------------------------------
--------------------------------------------------------LIKA
VTEKNFETKDFRASLENGVLLCDL--INKLKPGVIKKINRLSTPIAGLDNINVFLKACEQ
IGLKEAQLFHPGDLQDLS-NRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL
KAFENLLGQALTKALEDSS----FLKRSGRDSGYGDIWCPE-------RGE--FLAPPRH
HKREDSFESLDSLGSRSLTSCSSDITL-RGGREGFESDT---DSE-FTFK----------
---------M--------------------------------------------------
-------------------------Q-DYNKDDMSYRRISAVEPKTALPFNRFLPNK---
SRQPSYV------------------------PAPLRKKK-------PD----KHEDNRRS
WASPVYTEADGTFS----------------------------------------------
----RLFQKIYGENG---------------------------------------------
-------------------------------------------------SKSMSDVSAE-
---DVQNLRQLRYEEMQK--IKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER---
EEIEKQ-----ALEKSK----------RSSKTFKEML-----QDRES--QNQKSTVPSRR
RMYSFDDVLEEGKRPPTM-----TVSEASYQSERVE-EKGATYPSEIPKEDSTTFAKRED
RVTTE-------------------------------------------------------
---------I--------------QLPSQSPVEE--QSPASLSSLRSRSTQ----MESTR
VSASLPRSY---RKTDTVRLTSVVTPRPF-GSQTRGISSLPRSYTMDDAWKYNGDVEDIK
RTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKAT
LSS--------TSGLDLMSESGEGEISPQ-REVSRSQDQFSDMRISINQTPGKSLDFGFT
IKWDIPGI-FVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHL
VMDVRRYGKADWGKDQPSLPFIRHKTLNLTSMATKIIGSPETKWI-DATSGIY-NSEKSS
NLSVTTDFS--------------------------ESLQSSNIESKEING-IHDESNAFE
SKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISA-PSRWVWDQEEE---RKRQERW
QKEQDRLLQEKYQREQEKLR-----EEWQRAKQEAERENSKYLDEEL--MVLSSNSMSLT
TREPSLATWEATW-----SEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE
RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKR--------------------------
QAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNK
YLDQIGNTTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNS--WIRQ--RSASVN
KEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSN
RAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICS
YCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLG-GSSSGAEVRIRN-------HQLY
CNDCYLRFKS-GRPTAM--
>gi|125777348|ref|XP_001359577.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------EMPNKTDEQKRKEE
RGEREPI------YENVS-STISMHEVDNEQIATMTISTQIQTQTQIQTQTPIQGTQAST
RR---------------------SHRRSIPNKQTSNSNNNE-------NNQ--NTNQNS-
NSNGNSNQNENSIGGTAAISSDPEPYY----QVPKATEP---YYDAPKHLRP--------
---------I--------------------------------------------------
-------------------------P-VYENIDIFYTGLELSQISGPMPVGSMEP-----
-------------------------------P----KEK-------PP------------
-------PPPTESP----------------------------------------------
-------PPVPVDDA---------------------------------------------
------------------------------------------------------------
--------SLGHDDELDG--LGSSLGHNTDTWSSD-------------------------
------------------------------NTYETIS-----NGTRR-------------
-------HMQASQLEPAQ---PSPPIKRMNSTKRIK-KELRNKRSSFLGI----------
ETDGD-------------------------------------------------------
---------L--------------DDVESYLELTVAPPPDMAQLLQEERRL------EKQ
LYIKAGLCDS--SDTGDSRDS---------GVSENHSRQSSEHYTNSSE---END-----
---TQSEATPPPLPPPPVSGLGGEIIYQNETLLAAQTPLLQTVKGNSAESWTESATAAAA
ATQ--------SLSEATATANAKMQSIEEKIREQGEVLRVERELLHFSQEELKR------
--------------QRENLL----------------LRENIARRELQHGAKMLMSNNRRS
LQDLHHGLGI--------------------------------GNG-MLSAFQP-------
----------------------------------------------------PQMDTDYR
KS----------------------MSDLNEFS---------------------SRLMLAP
PKPPTKPLRAMHISNGHGLE-----PDYAVSTRQRQSSANAYGGSLV--KIAGAPMPPRH
SGSGYPPAVTASA--------AAAYHHQSAQNLSNM----SRNTLLA---LSATPKPKYT
--DGWVQV--QQRKSYDSNLANDPAWLSAQQQKR--------------------------
-------------------------------------------------------KSMPD
YNGAIYNNNHWLLQE-----------------AEQRRIEQLN------------RRSMPG
IKSNGKPLPDSIIQTLTERVQSKGIGER------------------------KRFDG---
-----------------------NGNYSQVNGNTNGYEK----------VLSVSGKKKCS
HCGDELGRGAAMIIESLLLFYHINCFKCCVCHVQLG-DGLNGTDVRVRN-------HKLH
CQNCYSSDDG-IKFSCV--
>gi|149703034|ref|XP_001494673.	Equus caballus
------------------------------------------------------------
------------------------------------MSSLSFLMM---------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------Q
VTGRSFGDKDFRTGLENGILLCEL--LNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKE
LGLKESQLFDPSDLQDTS-NRVTIKSLDYSRKLKNVLVTIYWLGKAANSCASYSGTTLNL
KEFEGLLAQ-MRKETDDIE----SPKRSIRDSGYIDCWDSE-------RSD--SLSPPR-
HGRDDSFDSLDSFGSRSRQTPSPDVVL-RGSSDGRGSDS---ESD-LPHRK---------
---------L--------------------------------------------------
-------------------------P-DVKKDDMSARRTSHGEPKSAVPFNQYLPNK---
SNQTAYV------------------------PAPLRKKK-------AE----REE-YRKS
WSTAT-SPLGGERP----------------------------------------------
---FRYGLRTPVSDD------------------------------------AE-------
-------------------------------------------------STSMFDMRCEE
EA-AVQPHSRARQEQLQL--INNQLREEDDKWQDDLARWKSRRRSASQDLIKKEEER---
KKMEKLLAGEDGTRERR----------KSIKTYREIV-----QEKERRERELHEAYKNAR
SQEEAEGILQQYIERFTI---SEAVLERLEMPKILE-RSHSTEPNLSSFV----------
---DD-------------------------------------------------------
---------P--------------N-PMKYLRQQSLPPPKFTATVETTITR----PSVLD
TSMSAGSGSP--SKTVTPKAVPMLTPKPY--SQPKNSQEVLKTFKVDGKFNMNGE-----
---MVHGDEEEKERECPTVE-LAPSLTKSQMFEGVAKVHGSPVELKQDSNSIEINIKKP-
-NS--------VPQELM-ATTEETELNSQEDENDGEKTEKGNTE--LASSEPQH------
---------FTTTVTRSSPT----------------VAFVEFPSSP-QPKNDVPEEKDQK
KLENEMSGKV--------------------------------ELV-LSQKVVK-PKSPEP
EATLTFPFL--------------------------DKMPETNQLH------LPNLNSQVD
SP----------------------GSEKSPVTTPQ----FKFWAWDPEEE---RRRQEKW
QQEQERLLQERYQKEQDKLK-----EEWEKAQKEVEEEERRYYEEER--KIIEDTVVPFT
ISSNSADQLSTSSSMTEASGTVNKMDLENCREEEET----RQKKPFQE--DNNDLLLKTR
EGDPVEEKGSLTQG--------------ALTHSE--------------------------
-------------------------------------------------------NPGSK
GIHQGDQWDA-EAGA-----------------PPCGVNPQLAQDPS--QNQQV-SNPPMH
VLEDVKPKTLPLDKSINHQIESPSERRK--------------------KSPRENFQA---
------------------------GHLSPCSHTPPGQSP----------TRSISGKKLCS
SCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLG-DAVSGTDVRIRN-------GLLN
CNDCYMRSRSAGQPTTL--
>gi|47227514|emb|CAG04662.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------MALLKE-----------DNLGVFLRGCEE
FGLKGSQLFDPGDLQDAS-TRPTAKGSDCTRKLKNVLITIYWLGRAANGCTSYSGPTLDL
KEFEGLLSQ-MRKEAEETE----SPKRNIRDSGYIDCWDSE-------RSD--SLSPPR-
HCREDSFDSLDSFGSRSRQTPSPDVLVARGSSDGRGSDS---ESDGPPHRK---------
---------M--------------------------------------------------
-------------------------P-DVRKDDMSVRRTSVTELRTPLPFNQYLPNK---
SNQSGYM------------------------PTPLRKKM-------ND----KDEGGRKS
WSTAT-SPVGGDRPCSLVPPSGESISPSHSQSCVPHVQLETVNHAKDSEGDQSASCTEIH
AVGLRSTPTRSCSEELLQHSTPLAANDSASQDVITSDKTALAMGATLAAEEEESLTSPQC
INTPSPSHFPAGSNGSAAADTSRQQGKAWSESEDLRGGASWTECGLRGTSVSMIDMRAEE
ET-LLQPHSQVRHELMHN--QYNKMKEEEDHWQDDLARWKNRRRSISQDLIKKEEER---
KMMEQLLSGDTCTSVRR----------RSIKTYREIV-----ADKERREQELRDAYRRAR
TPEEASSVLQRYAQRFSI---SEAVLEQLQLPKLLD-RSVSADPSCPCSPFALPVSSSSS
PTTPD-------------------------------------------------------
---------PFDTDP---------GGPLRYLRQQSAPAPKFTSTFEAQIQEFSKESSHQR
PQIRSRSSEPPAARGLSPKAVPLLMPKPYLQSQPPASEQWPS--KAGGLLPINGE-----
----MVGVNPPTSH---------------------GRESPPHFQASPSKHWTNNTESAPS
ATS---------------------------------------------------------
--------------PICSPH------------------------TPTEGETPASARAG--
----KTHGRT--------------------------------ETT-DVQRSTP-PSRPTT
------------------------------------------------------------
------------------------------------------------------------
------LPAEKYQREQEKLK-----EEWEKAQREVAEEERKYHEEER--RILEESRMPLT
PRSS-------------GVPTSSRGEASSSSEPHDTI---VRSLADW---ERKQELLERQ
LVNGWFLS--LSSICSRG----------LIGGDV--------------------------
-------------------------------------------------------VGRPA
DCFFVFDWTP-QRAS-----------------TENAEHKQRTNDRT--SDIST-ADDSMK
TGRSSLSQSPCLSETLQNGQKAAPVSTK--------------------SSTPVK--K---
-----------------------PEPTIDGNKQIRPTET----------RRSVSGKKLCS
SCGHPLGKGAAMIIETLSLYFHIHCFKCGVCKGQLG-DTTTGTDVRIRN-------GLLN
CHQCYIRSR----------
>gi|156544862|ref|XP_001607079.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MKR
EKQAHESVSHAPLRSSRICIECGV--AKRIPPFLGIALYNVL-PYAQVEPPVQNLIQLDE
EEEEEEEQPEQPEVQQPI-QESAVLVEETKEE----------------------------
----------EEEEEEEEE----QIIVEMEKKVEVE-KLKQ-------EEE----EPEEL
QSVEEEPELVPEFPAKMSEAPPVRPTTLALERTSICSDF---LSPLSPVSKQI-------
---------L--------------------------------------------------
-------------------------PLSFSSDEEIVTGLSFPLG----PPTSVEP-----
-------------------------------P---KEKP-------PP----PPIDLSDE
ENHPI-EPLK--------------------------------------------------
----RLNSTRRIKKE---------------------------------------------
-------------------------------------------------------LRSRR
S--DFLGIEGFNDEEFERELTLTKPPDMAAILAEERRIEQLHRRSYDTDSNYEQDSS---
HERDS------GVELGQ----------AEDWTKQPVS-----PDMSQHSRQSSEPFGASV
TSSEEDEISKKEREIIEV-------LEREEQWRYENNREIDSDIGEKLAH----------
------------------------------------------------------------
--------------------------KLRELEEEKMQLERERASAENQTLR---------
------------MNEENLRKQEELT------RQQDEAEALARQQELEKQKQVAEE-----
---EKRQEEEEKEEEA-------RLQKEQQLMMKEARRQED-LQRAAEISSQENKPMSPA
LSS----------------------CNEDEYASRQEVLRVERELLQLEQEELKR------
-------------------------------------------------QRNNLAYREQK
QQQLAEQLQE--------------------------------QWK-SLQDVAQAPPPPQP
RSQQFNGGN--------------------------KPIAAAPLNYRSSMPNLQMQEAAAQ
-----------------------------------------------------RRRPPPP
PIPPAKPLRLVEQRQ------------RDVTIRNS--------------RIPSADSIPQQ
VEAPLRPSISTS---------ALAPTQNSSSQQHHGQQMTRQTLQA----LSAVPRPRIV
QADQWVQRRK-------------------SDIPR--------------------------
--------------------------------------------------------GAHD
YNYQHWLIQEAEQRR----------------INEKNQRSPATRNPH--LTSTSVPYTASP
PRNDTKPLPDSIIQTLTQRVQNRVQDKP--------------------LSPRRRLEHSTS
QEHLHSPQHYQMQPHKVHQSPNNNNSNSSSNNSTESQEK----------MLSVSGKKKCS
HCGDELGRGAAMIIESLRLFYHMECFKCCVCHVRLG-DGLMGTDVRVRN-------HKLH
CHNCYSSDDG-VKFSCV--
>gi|114593780|ref|XP_001148320.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MRKETDDIE----SPKRSIRDSGYIDCWDSE-------RSD--SLSPPR-
HGRDDSFDSLDSFGSRSRQTPSPDVVL-RGSSDGRGSDS---ESD-LPHRK---------
---------L--------------------------------------------------
-------------------------P-DVKKDDMSARRTSHGEPKSAVPFNQYLPNK---
SNQTAYV------------------------PAPLRKKK-------AE----REE-YRKS
WSTAT-SPLGGERP----------------------------------------------
---FRYGPRTPVSDD------------------------------------AE-------
-------------------------------------------------STSMFDMRCEE
EA-AVQPHSRARQEQLQL--INNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEER---
KKMEKLLAGEDGTSERR----------KSIKTYREIV-----QEKERRERELHEAYKNAR
SQEEAEGILQQYIERFTI---SEAVLERLEMPKILE-RSHSTEPNLSSFL----------
---ND-------------------------------------------------------
---------P--------------N-PMKYLRQQSLPPPKFTATVETTIAR----ASVLD
TSMSAGSGSP--SKTVTPKAVPMLTPKPY--SQPKNSQDVLKTFKVDGKVSVNGE-----
----TVHREEEKERECPTVA-PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKP-
-NS--------VPQELA-ATTEKTEPNSQGDKNDGGKPRKGNIE--LASSEPQH------
---------FTTTVTRCSPT----------------VAFVEFPSSP-QLKNDVSEEKDQK
KPENEMSGKV--------------------------------ELV-LSQKVVK-PKSPEP
EATLTFPFL--------------------------DKMPEANQLH------LPNLNSQVD
SP----------------------SSEKSPVTTPQ----FKFWAWDPEEE---RRRQEKW
QQEQERLLQERYQKEQDKLK-----EEWEKAQKEVEEEERRYYEEER--KIIEDTVVPFT
VSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDR---RWKKSFQG--DDSDLLLKTR
ESDRLEEKGSLTEG--------------ALAHSG--------------------------
-------------------------------------------------------NPVSK
GVHEDHQLDA-EAGA-----------------PHCGTNPQLAQDPS--QNQQ--TSNPTH
SSEDVKPKTLPLDKSINHQIESPSERRK--------------------KSPREHFQA---
------------------------GPFSPCSPTPPGQSP----------NRSISGKKLCS
SCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLG-DAVSGTDVRIRN-------GLLN
CNDCYMRSRSAGQPTTL--
