>gi|120538271|gb|AAI29626.1|	Xenopus laevis
------------------------------------------------------------
--------------------------------MGKGLLG---------------------
------------------------------------------------------------
------------------------------------------------------------
--VLGGAVLLAVGLLIGHFG-----------------ITKTKTINPEWVEELSQDVD---
---------EAFIKEFMKEVDNKKIEEHLKELSK---KPHMATTTGDEELVKLILARWNH
AEYGLD---------------------------DAKQERYNVYLSFPDKNKPNTVKVLTD
NGQNPFTCRLTEANVTPDQEDP--EVVQPYAAYAPSGNPKGKLVYANQGKLSD----FQY
L-ADQSI-TLNGTIAIVRY-G-GAGRAAKAINGAKFGVVGIIVYTDPKDI----------
----------------------NDGLAERNQT------------YPYSWYMPESGVERGS
YSED---FGDLLTPYYPAK----DYTYRIKKSEINGIPPIPTQPIGFEDAKTLICQLAG-
-PVAP-QS--WQGSL---GCPYNLGPGFISSGKFNNSDVQVNV-YNYDEIKPSANVMGII
RGSVEPDRYVMYGNHRDSWVH-GAIDPSSGTAVMLEITRVLGTKLKQGKWRPR-------
-----RSIIFGSWGAEEFGLIGSTEFAEDYYSKLRDRTAAYINVDISVFANATLRAQGTP
PVQDVI-----FTAAKQVQTP----ASS--ALS--VYE-------NW--------IRYAN
RFSTLYQKTIPQLGTLGAGSDYAPFLHYLGISCMDISYTYDRNKTSARIYPAYHTAFDTF
DYAAK-FIDPGFTSHQTVARTAGNVLLRLSDSLILPLGPLDYWETLDSYYNTAESTF---
----------GSTLTSK----GISLAPLKAAVE--QFKKASEALKK-------TIDEL--
------------------------------------------------------------
KADNERPLSVRMI--NDQIMLLERAFINHYA----------------------FPEKRY-
YSHVLWASR------SSSV---VTFPGLADAYATASA-SNL-----------EDDWDLVR
KHLTIVIYAVTNAASTLETAASI-------------
>gi|19112025|ref|NP_595233.1|	Schizosaccharomyces pombe
----------------------------------------------------MTDEKHVY
VPPPKDPPSYEEVALHSALNNSAPPNDGEQNETSMEEME--IIEPPSEDSSRFPLLRTKL
AA----------------------------------------------------------
----------------------------------IHEGWESACHSFEIRFASTFH-RIPF
Q-FLYLAVIATVIILASYY------------------GYFDGVPAWRSVHH---------
-------YGEDVLLNYIKGCDISDTRQQVMTLSS---IPHLAGTVGDSSLLQMIMNRLY-
-YEKGT---------------------------IVDFREFYAYLNFPQ------LVSLSI
DGDDSFHPSLIESYQVGGYDGVSIPTPATFGG-SPSGFVNAPLVYANRGRIED----FEW
L-VNSGI-YVESSIVLVRA-N-QSDFALATANAEKYNASAILIFEDTYLT----------
------------------------SLDNLNQV------------YPAGPYPSANSLYRGS
VANHYYYVGDPLTPGWSAH----EETNRISPKDANVLPSIVSIPITFNDGIELLKRLQGH
GHLVKDSN--WCQDLAPVLSEVWTGSK------ISSPGLEVNVLQDIEDKQKIINIMAQI
DGY-ESDQILVVGAPRDSWCT-GASDSSVGTSLLIDVISTFANMAQDLSWKPR-------
-----RTIVFASWDARQFNAIGSTEFLEYWKESLEAKAVAYINVDVAVSGD-TFTARTVP
GLKKVI-----QRAFDVANEE----DEMKAANI--ITD----------------------
--------------DFDYTSDLTSFLTFAGIPVVNLAFERNEENPTP--MPFLGSCEDTV
SWIDT-FGSEYWENAARLGKIWSYLILFLANDPVVPYDLEDEINGVGEMLKRIPEIPGAN
----------ALDLRKI----NEEFSELLESLI--RFEDEIREWKS---LMMHNSYTV--
------------------------------------------------------------
SVKKHPEL--EGY--NAKLARFERSFLDEAG----------------------LPGHEW-
YKHLIYGPN------LRNSHS-QLFPSIFDALL-------------------YGDVEAAQ
KEVKRIALALDRAHNEIRFA----------------
>gi|109495415|ref|XP_222022.4|	Rattus norvegicus
------------------------------------------------------------
-------MEQRWGLLRKVQQWSPRPSQTIYRRVEGPQLE--NLEEEDREEGEELPAQFCP
MELKGP------------------------------------------------------
----------------------------------ERLGSCPGRSIPIPWAAAGRK-AAPY
L-VLTTLLIFTGAFLLGYVA---FRGSCQA-------CGDSVLVVGEDVNSEDSSRGTL-
-------YWSDLQDMFLRFLGEGRMEDTIRLTSL---RERVAGSARMATLVQDILDKLS-
-RQKLD---------------------------HVWTDTHYVGLQFPDPAHPNTLHWVGA
DGSVQEQLPL--------------EDPEVYCPYSATGNATGKLVYAHYGRRED----LQD
L-KAKDV-ELAGSLLLVRA-G-ITSFAQKVAIAQDFGAHGVLIYPDPADF----------
------------------------------SQ------------DPHKPGLSSDRAVYGH
VHLG---TGDPYTPGFPSF-----NQTQFPPVESSGLPNIPAQPISADVADRLLRKLTG-
-PVAP-QE--WKGRL--SDSPYRLGPG---------PGLRLVV-NNHRTSTPISNIFACI
EGFAEPDHYVVIGAQRDAWGP-GAAKSAVGTAILLELVRTFSSMVSSG-FRPR-------
-----RSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLGDGKFHAKTSP
LLVSLI-----ENILKQVDSP----NHS--GQT--LYDQVAFTHPSW-------------
--------DAEVIQPLPMDSSAYSFTAFAGVPAVEFSFMEDDRV-----YPFLHTKEDTY
ENLHKMLRGRLPAVVLAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEF----
----------SGDLKAR----GLTLQWVYSARG--DYIRAAEKLRK-------EIYSS--
------------------------------------------------------------
EQSDERLM--RMY--NVRIMRVEFYFLSQYV----------------------SPADSP-
FRHIFLGQG------DH------TLGALVEHLRMLRS-DGSGAASSGLSPGLGFQESRFR
RQLALLTWTLQGAANALSGDVWNIDNNF--------
>gi|50978812|ref|NP_001003111.1	Canis lupus
---------------------------------------------------------MMD
QARSAFSTLFGGEPLSYTRFSLARQVDGDNSHVEMKLAA--DEEENVDNNMR--------
------------------------------------------------------------
-----------------------------------------GNHASVPKPKRCNG-FICY
G-TIAVVLFFLIGFMIGYLG---YCKRVEPKAGC---ERPTGTEALGTERTEPSETEEYF
PETPSRLFWTDLKTMLSERLSNTDFTNTMRWLNENSYVPREAGSQKDESLALLIENRFR-
-EFQLS---------------------------KSWRDEHFVEIQVKSSNAQNTVTIVDM
ESDLVYLA----------------ESPEGYVAYSKATTVTGRLVHVNFGTKKD----FEN
L----KS-PVNGSLVIARA-G-KITFAEKVANAQSYNALGVLIYMDQARF----------
------------------------------------------------PIVNARIPFFGH
AHLG---TGDPYTPGFPSF-----NHTQFPPSQSSGLPSIPVQTISRAAAEKLFENMEG-
--DCP-SA--WEIDP---SCRLETSSN---------KNVNLTV-NNVLKEIRIFNVFGVI
KGFEEPDRYVVIGAQRDAWGP-GAAKSSVGTALLLELARIFSDMVLKGGFKPS-------
-----RSIVFASWSAGDFGAIGATEWLEGYLSSLHLKAFTYINLDKAILGTSNFKVSASP
LLYSLL-----EKTMKDVKHP----IT---GQS--LYR-----DSNW-------------
---------INKVEKLSLDNAAFPFLAYSGIPAVSFCFCEDTD------YPYLGTTMDLY
ENLNQ-KIPQLNKMARGAAEVAGQLIMKLTYDLELNLNYEMYNDRILSFVRDMNQF----
----------RTDIKEM----GLNLQWLYSARG--DFFRATSRLTT-------DYKNA--
------------------------------------------------------------
ERTNRFVM--REI--NDRIMKVEHNFLSPYV----------------------SPRDSP-
FRHIFWGSG------SH------TLPALVEHLKLRQK-NKS-----------AFNETLLR
NQLALATWTIQGAANALSGDIWDIDNEF--------
>gi|45190761|ref|NP_985015.1|	Ashbya gossypii
------------------------------------------------------------
-------MATNENLVDETNPLLPRPNTFAERQVLAA-----GARPRTNSVASL-------
------------------------------------------------------------
----------------------------------LARGRSNTIDSLRTTYAVVRR-HRT-
--GFAFILFVTFLVYCAFVL-----------------AFLPSTSISRDFRRLHFAKVTKD
---------EAYRLFVTSLLWENYAKGHMRHIAS---KNHPAG---DSRALKYTMRELR-
-AYGLN---------------------------PV-CETYYPYFNTPIRTEVS----IWT
NGLEAEKLSTWEDVLDQSQSTN--ISVAGFHGYSADGDVTAAYVYCGYGSAEE----YFY
L-LQNGI-QLAGKVHIVRE-G-RLHPGQKIRYAEAYGAVGVITYSDSCDD----------
---------------------GNVTTVHGYAP------------YPFGPAAHPSRLRRDS
VLFSNEIPGDPTTPGSVPW-----SPRTRRQLMNARVPRIPSVPISEREASKLLKLLNG-
-KGVR-VG--LGGNT--KGFDYHSGPS------DSNVQVRVLN-RQNYGMHAITNVIAEV
PGILK-DQEVVIGANRDSWAV-GAGESASATSILLEIARGLGAARKKG-WKPL-------
-----RSIKLISWDGEELGLLGSTSHGAAHNTSISDKTIAYFNLGNPVTGT-DFECEAHP
LVAGHL-----LDASKATNFK----EKF--SDT--LYD-------YW-------------
-----RNQSNLSIASPVSSSSYATFQHHLGVPSAECRFVNNRKDDA---IHHGHSSYDTY
TWMEK-LLDPDYELHNTLAMFVGLSALMLAENELVPFRTTDYMIELWRIYEDLHQPLKKA
FLHNEEVCVLYSALSSQLQLAAFHTAVSFDAFT--ASVRSKTIVDY-------PWWKL--
------------------------------------------------------------
REKLRIYNNLTSS--NRRMKLLDRIFIKQLG----------------------LAGRPW-
MKHTVFAPA------GNNCANCTMLPGLSEAIH-------------------AKDANSTI
KWLKSLSTQVDRVISLLTV-----------------
>gi|73983718|ref|XP_540872.2|	Canis familiaris
--------------------------MVKPEAQPVEKQKPEDPQVSEEPVLEPSSSEQKL
DSQPEPTVTFLFTLLSTAEPTESKDPEKASDIQECQFLD--KEDWGPRRTSREISHLQND
CRRLRESLSTIQADNRALREKLQNLLTVSYDSLKREAKAFLEEVKAAPEDARAFPKDAQA
IPGMALSQQLSSQKAALFIPQPAAPMTRRYQYQPWQGPRLETRHFLGKPFQELLS-RMKW
VNVLGGIVGAAALLGLGIIL-----GHFAI-------PKGSDVPTPSIFQDLDL------
----------EILESIMQQLDASRIRENLRELSR---EPHLASSPQDEALVQLLLQRWRD
PESGLD---------------------------SAEASTYEVLLSFPSREQPNRVAVVSP
TGNVLFSCRQSEQNLTGEQGGP--DVVPPYAAYAPPGTPQGLLVYANQGTEED----FMK
L-QAQGI-KLEGTIALTRY-G-GTGRGAKAVNAAKHGVAGVLVYTDPADI----------
----------------------NDGQSSTNET------------FPNSWRLPPSGVERGS
YYEY---FGDPLTPYLPAN----PSSFRLDPDNVSGFPPIPTQPIGFEDAKILLCNLQG-
-ASAP-AA--WQGAL---GCDYKLGPGFQPNGDFPADSVLLMP-LHRLQWLTSSGSTGLL
PGPLHPRGIVCFVPRREQWE--GADKWSKGTELELKLEAQLGTLLEQGTWRPR-------
-----RSIVFASWGAEEFGLIGSTEFTEEFFSKLQERAVAYINVDISVFANATLRAQGTP
PVQSVI-----FAASKQIPAP----SLG--GLS--IYD-------NW--------IRYFN
RS-SPVYGLVPSLGSLGAGSDYAPFIHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTF
GYVDK-FVDPGFSSHQAVARTAGSVLLRLSDSLFLPLNVSDYGETLRSFLQAAQQNL---
----------GVLLEQH----SISLVPLVTAVE--KFEGAAGALDQ-------RISAL--
------------------------------------------------------------
QKATPDPLQVRML--NDQLMLLERTFLNPRA----------------------FPEERY-
YSHVLWAPR------TGSV---ATFPGLANACSRAMN-TSLG----------SPAWAEVQ
RQLSILVVALEGAAATLRPVADF-------------
>gi|83767632|dbj|BAE57771.1|	Aspergillus oryzae
---------------------------------------------------MGNDSKFEY
EALPIPSYEEAVGARPSSSRSNLGPEANDESERQGLLHN-------VDDVTARESARPRP
HGYQPPTVESVRDSLDGLDSTGADSERGSLEELQRELHEMDVEDGDQQSSQRSR------
------------LLRSRFSKRISSLTRSLSAIHLPIRRFLPSFRFTIDLNGARTN-MRTH
G-CMIMLRLFGLFLVVLVVYIFFVSDLF---------NMNSRFIMGQSYSA---------
---------ASVENFVQGHVNETNIAENLKRVTN---FTHMAGTEGSYALAEWVKQEFK-
-IAGLD---------------------------DIEMEEFQVYLNYP-RDDGRRVAIVDP
P-DLFWEATLEETN----------EETPVFHGHSKTGNVTGPIVYANYGSRED----FRY
L-ADQGV-TVEGSIALVRYYGSESDRALKIKAAELAGAVGCIIYSDPSED----------
------------------------GFVRG-PA------------YPDGRFMPEDGVQRGG
VSLMSWVVGDVLSPGFASTP---DEKKRLKPEESQGLTSIPSLPIAWRDAQRLLQVIKGH
GSQVP-AK--WVGGV-PNVDQWWTGDG------TSPKVNLMNL-QDEEERQPIYNVLGRI
IGLEQPEKKIIVGNHRDSWCL-GSADPGSGTAVFLEVVRVFGELRTFG-WRPL-------
-----RTIEFVSWDAEEYNLIGSTEHVEKELEALRDNAYAYMNVDVGVSGN-EFEASGCP
LFERVV-----TQILGRISDP----VA---NET--LKE-------IW-------------
------EKKQKKLGPLGAGSDYVAFQDIAGTSSVDFGFVGEP-------YP-YHSCYENW
DWMVR-FGDPGFQYHKILAQFWGLLILQFADTPVLPFDLEVYADHIASYVIDLEKYAKSQ
NVPIAHDASSGKSNREV----TVTFKPLYDAAA--KVKDDAAQFQQWARVWHDTVLGT--
------------------------------------------------------------
GGFENNVIAAQRMDHNARMARFDTHLLDDRIDGG-------------------VPNRTQ-
FKHVLFAPE------LWSGYDATFFPAIRDSID-------------------SRNWTLTQ
EWVDRVSDILRTAGDKLLHG----------------
>gi|149635150|ref|XP_001512294.	Ornithorhynchus anatinus
---------------------MPAAPPSAPYSHPGARASRCTSIPVHSKARGHEHPGARA
SRCTRSSVHEHPGARASRGTSIPVPEHPGGRAARCTSILVPEEPGARASRSRSIPGHEHP
GALEARGTSIPVHSKLSARTSRSTSIPVPEHPGAREARCPSIPESEHP------------
--------------GVRASRYPSIPEPEHPGARASRYPRMWTLLQERTEPILRRGGRSPA
PLALSILLFLLLLLLLGFLI-----GWL---------TKPSSNCSTVSPP----------
---------GSMKKSFLAEMKAENIKKFLYNFTR---LPHLAGTEQNFLLAQQIQAQWK-
-EFGLD---------------------------SAEIAHYDVLLSHPNETDPNYIAIVDE
DGNEIFNTSLFEPPPEGYENVS--DVVPPFSAFSPRGEPEGDLVYVNYGRTQD----FFK
LERDLGI-NCTGKIVIARY-G-KIFRGNKVKNAQLAGAIGVILYSDPADY----------
-------------------------CAPGVEP------------YPKGWNLPGGGAQRGN
VLNLNG-AGDPLTPGYPAT----EYAFRYELAEAVGLPRIPVHPIGYHDAQKLLENMGG-
-SPPPEKS--WKGSL---NVSYNLGPGF--TANYSSRKVKMHI-QTNNKVMRIYNVIGTL
RGAVEPDRYVILGGHRDSWVF-GGIDPQSGAAVVHEIVRSLGKLKKEG-WRPR-------
-----RTMLFASWDAEEFGLLGSTEWAEENSRILQERGVAYINADSSVEGNYTLRIDCTP
LMYSLV-----YNLTKELPSP----DEGFEDKS--LFE-------SW-----------YE
KNPSDEFIGVPWINKLGSGNDFEVFFQRLGIASGRARYTKNWKVDRFSGYPVYHSVYETY
EMVDR-FYDPTWKNHLTVAQVRGGLVFQLADSIILPFDCRHYAEALEKYARNIYDIAKKY
----------QKELESY----QVSFDSLFSAVR--NFTVTAADFHG-------RLQQV--
------------------------------------------------------------
DPNRPVSV--RSA--NDQLMFLERAFIDPLG----------------------LPGRPF-
YRHVIFAPS------SHNKYAGESFPGIFDALFDIGN-HPDP----------PKAWAEVK
RQISIAAFTVQAAAGTLKEVA---------------
>gi|57770544|ref|NP_001009916.1	Danio rerio
---------------------------------------------------------MMD
SVTGLITGAAGGGAQANEGVEEGGGVRRRAPPIEMKLVPLEGSDVTLNSD----------
------------------------------------------------------------
-----------------------------------------ITALMLQQHVNRRK-AAVY
L-TLTGLLIFTTAFLLGYVA---FRGMCHLCR-----SEPDNIPLSDALGDDRQPEEVVL
-------YMAELREMLKKYLKEERIENTLRRVSR---ESHPPGSSEGNAIAREILQNLQ-
-NLGMD---------------------------HTWTDSHYATLQFPSRTHRNTLWLVDS
EGAELEEIRL---------------DSEGYCAYSATGTATGGLVYVNYGRRED----FDQ
L-RVMGV-SLNGSIAMVRVGG-GVSFAEKVWLAQEAGHVGVLIYPDPADV----------
------------------------------PQ------------DPRRLGLHSNAVISEH
VHLG---SGDPFTPGFPSF-----NHTQFPSTQSSGLPIIPAQPISANVAAKLLSQLSG-
-AVCP-RG--WQGRL--PYVQCVLGPGF--SG-VGVRQLKMAV-YNSMKPVLLNNIFASI
EGKVEPDHYIIIGAQRDAWGP-GAVKSGVGTALLMELARTFSNMVENG-FSPR-------
-----RSLLFVSWDGGEFGNVGATEWLEGYLTMLHLKAVAYFSLDQAILGDDVLSVYSSP
LLSHLI-----EGAIKQVEHP----KHT--GQS--ILS-LVQRQGGW-------------
---------RNIVKPLYLNSGAYSFTAFGGVPAMQLHFTEDXRS-----YPFVNTQLDSV
GRLQELLQGRLGSVGRAVGELVGLMVLKLAHDHILPLDVSCYSSSAQQLSSTLSQH----
----------AAQLQSR----GLSPQWVFSARG--DYSRAAKNLLE-------AIKNS--
------------------------------------------------------------
DTQDEKLA--RLY--NTRIXRVEYYFLSQYV----------------------SVVETP-
FRHVFLGRG------DH------TMSSLADHLNQLRL-EPH-----------RFDEARFR
KQLALFTWTLQGAANALSGDVWNIDNPL--------
>gi|71896251|ref|NP_001025553.1	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MARK-RSTR
RTCLLICLTMALLFLLGILV-----GWL---------IKPSEERIAPPTQ----------
----------NIRKELVSEMKAENIKQFLRDFTK---IPHLAGTEQNLELAKRIQKQWM-
-DFGLD---------------------------SAKLVHYDVLLSYPNSSNPNYISIIDG
HGNEIYNTSLFEPPPTGYENFT--DIVPPYNAFSAQGDPEGDLVYVNYGRTED----FFH
LERNMGI-NCTGKIVIARY-G-KIFRGNKVKNAMLSGAKGIILYSDPADY----------
-------------------------CAPGVEP------------YPHGWNLPSGGVQRGN
VLNLNG-AGDPLTPGYPAK----EFTYRYEADEGVGLPSIPVHPIGYRDAEEILRLMGG-
-APPP-SA--WKGNL---DVPYNIGPGF--LKNISTGKVRMHV-HSNNEVTRIYDVIGTI
RGAVEPDRYIILGGHRDSWVF-GGIDPTTGAAVLQEIARSFGKKVREG-WRPR-------
-----RTIIFASWDAEEFGLLGSTEWAEENAKILNERAVAYINSDSAIEGNYTLRVDCTP
LMYRLV-----YNLTKEIASP----DQGFEGES--LYE-------SW-----------RQ
KDPSIENKEIPRINKLGSGSDFEAYFQRLGIASARARYTKNRKTDKYSNYPVYHTVYETF
ELVER-YYDPSFKKQLSVAQVRGSLVYELANAPVIPFNVQDYGEALKSYATSIYSLAKRN
----------RSQMETY----GVSFEPLFSAIQ--NFTEASDGLHQ-------RLEKL--
------------------------------------------------------------
DHHNPLAV--RIM--NDQLMFAERAFTDPLG----------------------LPGRQF-
YRHVIFAPS------SHNKYAGESFPGIYDALFDIEN-KADQ----------YRAWEEVK
RQISVAAFTVQAAAETLQEVA---------------
>gi|148687312|gb|EDL19259.1|	Mus musculus
-------------GQTVPPPLWGMRNGLGSGCLSGLIRGPLGLPQTVYRGFVCVCVDYLQ
SSGGGTSMEQRWGLLRRVQQWSPRPSQTIYRRVEGPQLE--HLEEEDREEGAELPAQFCP
MELKGP------------------------------------------------------
----------------------------------EHLGSCPGRSIPIPWAAAGRK-AAPY
L-VLITLLIFTGAFLLGYVA---FRGSCQA-------CGDSVLVVDEDVNPEDSGRTTL-
-------YWSDLQAMFLRFLGEGRMEDTIRLTSL---RERVAGSARMATLVQDILDKLS-
-RQKLD---------------------------HVWTDTHYVGLQFPDPAHANTLHWVDA
DGSVQEQLPL--------------EDPEVYCPYSATGNATGKLVYAHYGRSED----LQD
L-KAKGV-ELAGSLLLVRV-G-ITSFAQKVAVAQDFGAQGVLIYPDPSDF----------
------------------------------SQ------------DPHKPGLSSHQAVYGH
VHLG---TGDPYTPGFPSF-----NQTQFPPVESSGLPSIPAQPISADIADQLLRKLTG-
-PVAP-QE--WKGHL--SGSPYRLGPG---------PDLRLVV-NNHRVSTPISNIFACI
EGFAEPDHYVVIGAQRDAWGP-GAAKSAVGTAILLELVRTFSSMVSNG-FRPR-------
-----RSLLFISWDGGDFGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLGDGKFHAKTSP
LLVSLI-----ENILKQVDSP----NHS--GQT--LYEQVALTHPSW-------------
--------DAEVIQPLPMDSSAYSFTAFAGVPAVEFSFMEDDRV-----YPFLHTKEDTY
ENLHKMLRGRLPAVVQAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGNLNEF----
----------SGDLKER----GLTLQWVYSARG--DYIRAAEKLRK-------EIYSS--
------------------------------------------------------------
ERNDERLM--RMY--NVRIMRVEFYFLSQYV----------------------SPADSP-
FRHIFLGQG------DH------TLGALVDHLRMLRA-DGSGAASSRLTAGLGFQESRFR
RQLALLTWTLQGAANALSGDVWNIDNNF--------
>gi|121705612|ref|XP_001271069.	Aspergillus clavatus
---------------------------------------------------MTNDKKFDY
EALPIPTYDEAVSSRPGSSRSHLGPDEASDDAERQGLLH--DADGNSHSATGNGSQRSRP
HGYRPPTVESVRNSLDDLASSDGDSARGSLEDLQRELAQMDVEDAGQQSTSQRS------
------------RLGQQFSKRFNTLSRTLSSIKLPFRRWLPNFRFTINLGEVRPH-FKDQ
G-CIVLLRVFGVLLVVTIVYVFFFSNIF---------GLNSRFTMGQSYSA---------
---------ASVQNFLQGHINETNIAENLRKVTK---FPHMAGTEGSYVLAEWIEQEFK-
-NAALD---------------------------EVEMEEFQVYLNYPTQD-GRRVAIVDP
P-ELAWEAALEERN----------EQTPVFHGHSKSGNVTGHLVYANFGSRED----FQV
L-ADKGI-DLHGAIVLVRYYGTESDRALKIKLAEMAGAAGCIIYSDPGED----------
------------------------GFRKG-PA------------FPDGRFMPDDGVQRGA
VSLMSWVVGDVLSPGFASTP---EEKKRLSVEESPGLLGIPSIPIAWRDAQRLLQVLEGH
GAPVP-EK--WHGGV-PRVKEWWTGDG------SSPKVNLMNL-QDEVERQPIYNVFGRI
IGLEQPEKKIIVGNHRDSWCL-GSADPGSGTAVFLEVVRVFGELRTFG-WRPL-------
-----RTIEFVSWDAEEYNMIGSTEHVEKNIEPLRDHAYAYLNVDVGVSGN-EFTASGSP
LFQRIV-----MQILSRIADP----IT---NET--LKD-------IW-------------
------EKAQKTFDSLGSGSDYVAFQDIAGTSSVDFGFTGQA-------FP-YHSCYENY
DWMTK-FGDPGFQYHKALGQFWALLLIDLADNPILQYDLQAYADHMQTYVADLVAYAKTQ
NVPVAPPPSEGHAIRET----SVSFQPLFDAAA--KLKSDADEFEKWAQLWRTTVWDA--
------------------------------------------------------------
GGFENNVMAIQRLRHNARLGGFDAQLLDREQGGG-------------------IPNRTQ-
FKHVVFGPQ------LWSGYDAATFPAIRDTID-------------------TGNWTLTQ
EWIDRVSQIIQDASSSLLRH----------------
>gi|50303587|ref|XP_451735.1|	Kluyveromyces lactis
------------------------------------------------------------
------------MSIPYDEETQPLVPRGVTRRRDNSVAS--F------------------
------------------------------------------------------------
----------------------------------LARGRSNTINSLKSGFETVKK-HKN-
--EFWLLIIGSLVLYLGFTL-----------------AFLPRTSLSRDFRRLHFSKLTKS
---------EAFRIYVETLMKENKCQDHLSNYTS---HIHWAG---DAHALEYTINELS-
-MLGFT---------------------------P-KLEEYHTWLNEPVKTEVT----LWD
QNHLLYNASMTEDYISEGEDNDSFKKVFGFHGFSANGTVRSEYVYCNYGTIED----YEH
L-LSHNV-KLEGKIHVIRY-G-AIMKGIVVKNAETFGALGAILYTDSFDD----------
---------------------GLITENNGYKP------------YPEGPARHESSIERGS
VLLVDSVAGDPTTPEYSSKH---KDVKRLNS--SSNLPTIPSVPMSEREIAPLLKLLNG-
-NGIQ-----WETKGNVKGFQYFSGPS------DAGVSCRIVN-EQKYLTKEITNVVIEI
PGILK-EQEVIIGNHRDSWTSGGAGGPNSGSSILLEIARGFSALHQKG-WKPL-------
-----RTIKLISWDGGEQGMLGSTEYGEYHRESLSKGTVAYFNLDLGVIGS-KLNIKANP
LLNELI-----VRSSKRTLFK----EDP--EVT--LYD-------YW-------------
-----KESSNATIDILGAGTDFAVFQNNLGIPSIDFSFDRDPKKDA---VHQFHSSYDSF
EWMKT-FVDPDFSLHSTMAMFVGVSTLSLTENELLGFKTHEYMIEISKYYKTLYSNISEV
FPNDEMIMTLKDNLVDLLELLTTHTTLDFDAMV--DFVREQTQQDY-------PWWEW--
------------------------------------------------------------
NKKLVILTRLIST--NSKLRKLDRYFITDEG----------------------LKGRPF-
MKHSIFAPD------KQTGYQGDVLPGLHEALL-------------------SENRQECI
YWLETLLTQLDKISSLLTI-----------------
>gi|114590445|ref|XP_001166648.	Pan troglodytes
----------------------------------MGENEASLPNTSLQGKKMAYQKVHAD
QRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDSAENQNLGHSETIDLNLDS
VQPATS------------------------------------------------------
---------------------------PKGRFQRLQEESDYITHYTRSAPKSNRC-NFCH
--VLKILCTATILFIFGILI-----GYYVHT------NCPSDAPSSGTVD----------
---------PQLYQEILKTIQAEDIKKSFRNLVQ------LYKNEDDTEISKKIKTQWT-
-SLGLE---------------------------DVQFVNYSVLLNLPGPS-PSTVT-LSS
SGQCFHPNGQPCSEEARKDSSQ--DLLYSYAAYSAKGTLKAEVIDVSYGMADD----LKR
I-RKIK--NVTNQIALLKL-G-KLPLLYKLSSLEKAGFGGVLLYIDPCDL----------
--------------------------------------------------PKTVNPSHDT
FMVSLNPGGDPSTPGYPSV----DESFRQSR---SNLTSLLVQPISASLVAKLISS----
-PKAR-----TKNEA---CSPLELPNN-------EIRVISMQV-QTVTKLKTVTNVVGYV
MGLTSSDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRG-WRPD-------
-----RTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASP
SLQQLVVEKNNFNCTRRAQCP---------ETN--ISS----------------------
-------------IQIQGDADY--FINHLGVPIVQFAYEDIKTLEGP--SFLSEALFSTR
ATKIE-EMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEV--------------
----------QNNLKGD----EPNTHQLLAMAS--RLRESAELFQS-----DEMRPAN--
------------------------------------------------------------
DPKERAPIRIRML--NDILQDMEKSFLVKQA----------------------PPG--F-
YRNILYHLD------EKTS----RFSILIEAWEHCKP---------------LASNETLQ
EALSEVLNSINSAQVYFKAGLDVFKSVLDGKN----
>gi|119588266|gb|EAW67860.1|	Homo sapiens
------------------------------------------------------------
----MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLL--GFLFGRGAPRGANLGVF--
------------------------------------------------------------
----------------------------------PVVPRCWDSRVKSQLQGLMTA-GSSY
P------LFLAAYACTGCLA--ERLGWF---------IKSSNEATNITPKHN--------
------------MKAFLDELKAENIKKFLYNFTQ---IPHLAGTEQNFQLAKQIQSQWK-
-EFGLD---------------------------SVELAHYDVLLSYPNKTHPNYISIINE
DGNEIFNTSLFEPPPPGYENVS--DIVPPFSAFSPQGMPEGDLVYVNYARTED----FFK
LERDMKI-NCSGKIVIARY-G-KVFRGNKVKNAQLAGAKGVILYSDPADY----------
-------------------------FAPGVKS------------YPDGWNLPGGGVQRGN
ILNLNG-AGDPLTPGYPAN----EYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGG-
-SAPPDSS--WRGSL---KVPYNVGPGF--TGNFSTQKVKMHI-HSTNEVTRIYNVIGTL
RGAVEPDRYVILGGHRDSWVF-GGIDPQSGAAVVHEIVRSFGTLKKEG-WRPR-------
-----RTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTP
LMYSLV-----HNLTKELKSP----DEGFEGKS--LYE-------SW-----------TK
KSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETY
ELVEK-FYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKH
----------PQEMKTY----SVSFDSLFSAVK--NFTEIASKFSE-------RLQDF--
------------------------------------------------------------
DKSNPIVL--RMM--NDQLMFLERAFIDPLG----------------------LPDRPF-
YRHVIYAPS------SHNKYAGESFPGIYDALFDIES-KVDP----------SKAWGEVK
RQIYVAAFTVQAAAETLSEVA---------------
>gi|115748977|ref|XP_784853.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------MSLEESPSGAAYESLGADDSV---------------------
------------------------------------------------------------
---------------------------------------LTFRKSEQKRGTMGRG-NRSH
L-ILIWIVGLCIGVGVGVLI-----GWFSSQA-----KFPDEEAYNLWRQALTEEDA---
---------QKISKLLIDELKADNIKENLRYLTS---RPHLAGTPADKENAEWVKDRWI-
-EQGLD---------------------------SANVIPYKVLLSYPNVDKPNYLS---K
RGNNYTDVT---------------HIVPPFNAYSANGTVTGELVYVNYGRIED----FQK
LTGELHI-DLTGKIAIARY-G-KIFRGDKAKHATKYGAAGLILFSDPADYAVENDLGVYP
DTWYLPGTGVQRGSLHIPMGLGGDPLSPGYPSYADYAVESDLGVYPDTWYLPETGVQRGS
LYSYQSVGGDPLSPGYPSY----ETAYKIS-EDAAGLPTIPVQPIGYGDAKMILEQLAG-
-PKAP-DE--WQGNI--HNLTYNLGPGY-----VGGRTVKLEV-NTRNEERFTYNTIGII
RGSIEPDRYIIAGNHRDAWVY-GAVDPSSGTAALMEMSRAMGKLVKDGKWRPR-------
-----RSIVFASWAAEEYSLIGSTEWVEEFTKNLGSRTVAYLNIDISVEGNYTFRLKSTP
NLYEAV-----FSATKNV--P----DVPFPGHSSTVYD-------TW-----------LD
R--TGKGGDRPSVRNIGSGSDYASFLGEIGVPSVDLRYTFNSDLGLSS-YPLYHSMYETF
FLVSE-IMDHSFEYHLAVTRVWAELARSLADSLILPIGVVDTAEKITGSIATLKDFY---
----------EDQMAEQ----GITWDTIESASS--NLTTAAKAFES-------NVADM--
------------------------------------------------------------
EKNDPFAV--RRV--NDQLMQFERAFIDPLG----------------------LPGRNL-
QRHVVFAPS------SKDAYKGDAFPGIVDLMFDINNPEGDV----------SDDWEALK
QHMSVVAFTLQSAASTLKDVDILHRD----------
>gi|6322586|ref|NP_012660.1|	Saccharomyces cerevisiae
---------------------------------------------------------MRM
IQRERKREKEEGQLKERTVVNMADPDDNEAEATGLQQYS--GETTRDDNEESMNDSFTLT
S-----------------------------------------------------------
----------------------------------RNRGRSNTISSIVSGYEIMKE-HMDK
E-KFMYLILASLLLYMGFVA-----------------AFAPRTSLSRDFRRFHSSRLTNA
---------EVYRIYLNSLQQENRAKEHVYKYAG---Y--MSNGASDSSTFKYTLDEFL-
-DMGYK---------------------------PK-VEKYYPWIGEPVDTNVAPL----E
NGKVVYEASMIEDRVKGDPASHARKRQKGFHQYSKNGSVTARYVFCNYGSISD----YKL
L-LKKNI-DIEDKIHIVRS-G-KILPGLKVKNAELYGASSVIIYTDPFDD----------
---------------------GKVTEENGFLH------------YPYGPARNPSYIRRDS
VNYFSDTPGDPTTPGYPSKD---SDTEHMSP--VGRVPRIPSVPMSARDVQPILERLNG-
-RGFQ-IG--PGSNI--KDFGSFTGPS------SSIDKVHLHN-ELTYNIKEMSSVEVSI
PGIFT-EGEIIIGAHRDSLASSSAGDANSGSAILLEIARGMSKLLKHG-WKPL-------
-----RPIKLISWDGERSGLLGSTDYAEAHAAILRRRALVYLNLDNAISGT-NFHCKANP
LLQDVI-----YEAAKLTEFN----GHE--DWS--LFD-------HW-------------
-----KYTSNATISLLDGLSSYTSFQYHLGVPAAHFQFNANDTSGA---VYHSNSVFDSP
TWLEK-FTNSDYKLHNTMAMFVGLTTLMLSENELARFNTHVYLKKIYNWYIAWHSNLSSA
FPQDDE----VNSLAKR----VLDLLKVATQEDSIQFDQQNGILYKECREAL-PVWAF--
------------------------------------------------------------
YKKIKSYIKLQRS--NSKSKQIDQLFITHRG----------------------LKDREW-
MKYSLLAPS------KFEGSVGEVLPGLHEGLA-------------------DIDRNEVI
QWLTILLSQFSNVRYLLQ------------------
>gi|45383950|ref|NP_990587.1|	Gallus gallus
----------------------------------------------------------MD
HARAALSNLFSVEPMSYTRFSIARQTDGDNSHVEMKLSA--DDEEGGDIERPE-------
------------------------------------------------------------
-----------------------------------------HMHVSMAQPQRNGK-RLCF
L-VIAAVLLLLIGFLIGYLS---YRGRIELAARCQDGSGGCEITPTASYLVDGEGTVEEE
IQGPPVIFWPELKAMLSKKLSAKNLVDNLRWRVG--VDSFEAGEAEDTNMATYIHEEFR-
-NF-LD---------------------------KVWNDEHYIKLQVRGSTKNQVSISING
KEEIL-------------------ETPDAIVAYSESGSVSGKPVYVNYGLKKD----FEI
I-QKVVA-SLNGTIVIVRA-G-KITLAEKVANAKEAGAAGVLMYVDSLMY----------
-------------------------------------------------GITDTLIPFGH
AHLG---TGDPYTPGFPSF-----NHTQFPPVESSGLPHIAVQTISSSAAARLFSKMDG-
-DTCS-EG--WKGAI--HSCKVTTKQE-------SQIMVKLDV-NNSMKDRKILNIFGAI
QGFEEPDRYVVIGAQRDSWGP-GVAKAGTGTAILLELARVISDIVKNEGYKPR-------
-----RSIIFASWSAGDYGAVGATEWLEGYSAMLHAKAFTYISLDAPVLGASHVKISASP
LLYMLL-----GSIMKGVKNP----AAV--SES--LYN---RLGPDW-------------
---------VKAVVPLGLDNAAFPFLAYSGIPVLSFGFYNKDEE-----YRFLDTKGDTL
ENLRK--IDNLDALLAAAAEVAGQAALRLTHDHELFLDIGRYSEELLAYQEEFLPY----
----------IKEVREL----GLTLDWLFFARG--DFQRAVTALRR-------DIANS--
------------------------------------------------------------
DGENRVIR--RAL--NDRMMKVEYDFLSPYL----------------------SPKDVP-
FRHIFFGKG------PH------TLRSLVEHLQLLKT-NRS-----------SVDLNLLR
EQLALATWTIKGRPMPWEVISGKLTMNSRH------
>gi|149731410|ref|XP_001495703.	Equus caballus
MENEGMVILAIVWKFSEQGINKFRETSKEAILVKSDDGLNLIVSSGKKGKKMAYQKVNAD
QRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFRLDRAENQNLENSETADLNLDS
IQPATS------------------------------------------------------
---------------------------PKGRFQRLQEESEYVTRYTRSAPKSNPC-NFCR
L--SKMLCTAIILFIFGILI-----GYYAHK------NCPSNATSSGTLD----------
---------LQLYQEILKTIQAEDIKNSFRNLIQ------LYKSEDDVEISKKIKTHWT-
-SLGLE---------------------------DVQFVNYSVLLSLPGPS-PSSVT-LSS
SGQCFHPNGQPCSEEARKHGSQ--DLLYPYAAYSAKGTLEGEVIDVGYGKADD----LKR
I-KKMK--NTTNQIALLKL-G-KLPLLYKLSLLEKAGFGGVLLYIDPCDL----------
--------------------------------------------------PKTTNLSYDT
FMVSLNPGGDPSTPGYPSV----DGSFRQNR---SDLTSLLVQPISASLVAKLISSPQD-
------RT--KNGVC----SPLELPNN-------EERIVNMQV-QTVTKFKTVTNVVGYL
KGLTSPDRYVIVGSHHHTAYSYNGQEWASSTAIITAFIRALMLRVKRG-WRPD-------
-----RTIVFCSWGGTTFGNIGSYEWGEEFKKVLQRNVVAYVSLHSPIRGNSSLYSVSSP
SLQQLVAEKSNFNCSRRAHCP---------GTN--VSS----------------------
-------------VQIRGDADY--FINHLGVPTVQFAYEDIKALESP--SFLSEALFLKR
ATKIE-EMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEV--------------
----------QNNLKGD----QLNPHQLLALAS--RLRESAQVFQS-----DEMRPAN--
------------------------------------------------------------
DPKERAPIRVRML--NDILQDMEKSFLVQQV----------------------PPG--F-
YRNILYHVD------EKTS----QFSILLEASEHCKS---------------LPSNETLQ
EALSEVLNSINSAQVYFKAGLDVFENVLVGKN----
>gi|119917178|ref|XP_875342.2|	Bos taurus
------------------------------------------------------------
-------MEQLGGLLRRAQRLSPGPSQTIYKRVEGSQQGRLEEEEEEGEEGTEPPAHFFP
MELRGP------------------------------------------------------
----------------------------------EPLGSRPARQNPGLWAAAGRR-AAPY
L-VLTALLIFTGAFLLGYVA---FRGSCQA-------CGDDVMVVSEDVNDELSPDSHQG
-----TLYWSDLQAMFLRFLGEGRLEDTIRQTSL---RERVAGSAGMAALAQDIRAELL-
-RQRLD---------------------------HVWMDTHYVGLQFPDPARPNTLHWVDA
SGKLGEQLPL--------------EDPDVYCPYSATGNATGKLVYAHYGRPED----LQE
L-RARGV-EPAGRLLLVRL-G-VINFAQKVASAQDFGAQGVLIYPDPADF----------
------------------------------SQ------------GPHKLSLSSHRAVYGH
VHLG---TGDPYTPGFPSF-----NQTQFPPVQSSGLPSIPAQPISADIASLLLRKLEG-
-PVAP-QE--WQGHL--PVSPYRLGPG---------PGLHLGV-SNHRASTPISNIFGCI
EGRSEPDQYVVIGAQRDAWGP-GAAKSAVGTAILLELVRTFSSMVSNG-FQPR-------
-----RSLLFISWDGGDFGSVGSMEWLEGYLSVLHLKAVVYVSLDNAVLGDDKFHAKTSP
LLIGLI-----ENILKQVDSP----NRS--GQT--LYEQVVVTNHSW-------------
--------EAEVIRPLPMDSSAYSFTAFAGVPAVEFSFLEDGPA-----YPFLHTKDDTY
ENLHRVLRGRLPAVAQAVAQLAGQLLIRLSHDHLLPLDFGRYGDVVLRHIGSLNEF----
----------SGDLKAR----GLTLQWVYSARG--DYIRAAEKLRK-------EIYSS--
------------------------------------------------------------
EESDERLM--RMY--NVRIMRVEFYFLSQYV----------------------SPADSP-
FRHILLGRG------DH------TLHALLDHVRLLRA-GGPGATSSQVARGLGFQESRFR
RQLALLTWTLQGAANALSGDVWNIDNNF--------
>gi|150864957|ref|XP_001383985.	Pichia stipitis
-----------------------------------------------MASHMRYTPLTAD
PSHTLPSFPPSYDDLDDNNDDYTYSSSATPAIEQFELDD--GIDGIDDGITRRTQREGLL
VRASLMTKKFANNFNNSIIHPVSQI-----------------------------------
----------------------------------IDPIYEGYKYFQQKYEQNILK-LGNP
L-VVKRLLYVLFIMIVIFFV---TKHNV---------NDGVNGTSGGTFSAGKFYNI---
---------DKLSSSVDDFISAKLMKENLEYFSS---MSHITGSNGDLTLARYIETYMH-
-NNGIR---------------------------IMDMNQLQSYTNYPVYNEKDTYLKLSD
NSFSAHLYEMNNKTME--------HLAYNPNALNTNGPVESHFIYGNYGTQED----YQK
L-ISSGI-DLTDAILLIKYGG-SIPEPNKVSFGQQSKVKAIVFITPKFEF----------
------------------------GTGDSKQE------------FVDVIQKANVGLTRVD
-------PGDVLTPGWSSED---GYVTRLPWFRSSTTPKIPTIPISWEDGEKLLSKLEG-
-SGVK------------FDDGYFSGKGK--SS-SVPTMVLKIA-NEERATHQIWNVVGSI
QGREQNEKGIIIGSSRDSTCY-GTISSNTGTVVMLEMIKVFTSLQRKYNWSPS-------
-----RSIYFVSFDATEYNLAGSAEWIENRKDSLRKEGYAYIDLSDAISGD-DLSIKASP
FVEDVI-----KKALKQVETDVTKNDNGNEKLS--LYD-------LY-------------
---LRQQGNDGISNDLIESKNYIPFINLVNMPSLELKFSGKK-------YP-KNSCYDNF
ENFEKSAIDPDMNKHRELVKVLSLIALRLAESPMIPFDFQKLASKLTHYVDDLEKYSRDI
----------ISTLEQENKP-VLHFKSLRDSIE--ILRNAANSLQSWGDSWKQYVENS--
------------------------------------------------------------
AEIEPSMLAMNRWKRNENMVAFNQKFLVRNH----------------------MKDTRPG
FANVLFGVPFMAPEVSDGKYEWNTFPRIRDSLY-------------------LHDFNAAQ
DQINKLASLVQEACQELDSQ----------------
>gi|58258587|ref|XP_566706.1|	Cryptococcus neoformans
---------------------------------------------------MGKEDSQRS
ANHPVTVTPHISSTHDLIQLPLPNTISHNNARSGASFAV---------------------
------------------------------------------------------------
---------------------------------RVTIGTLILLWTLFNIDVVTSP-FRQN
PSIDSLDDSSAAGYLRGIAT--KSMKWA---------LPAPNHQLHSTYGDLESTEIGEE
GIKMSLIPPKLAEKIFLDVPSNDSVAAASKRYTG---YAHPAGSGYDYASALTLKNEWEK
-ELGLRVSGPQEFIYDAGSPESQARVKNGMDKLGVWIDTYYPVMNTPVYAAATLLT----
--DPPFHAKLREDIVDGDSDSELRDEVPVFHGLSVSGDVRGNFVYVGYGRKKD----FDL
L-KQRGV-DIDGKIVLAKY-G-GCFRGLKVKAAQEAGATGVIIFTDPGND----------
---------------------GEITEENGYEV------------YPKGPARQLSKY----
-------PGDPSTPGEPAY----KNASRL---EGGNQPSIPSIPMSYEDVIPFLKALEGK
GIHASDLGPDWVGGLGYHGVDYYIGPS--------DVDLHLVN-EVNTRVMPIWNTMAVI
PGHIT-DEVIILGNHRDAWVL-GASDPNSGTASQFEVIRGLGTLLRKG-WKPL-------
-----RTIMLASWDAEEYGLIGSTEWAEDFGDWLQTNAAAYLNMDSSASGS-NFHASASP
SLALLV-----RSAAEEVESS----SSP--SKS--VFD-TRFDAGNWEQFNMEKLGNHVG
LGVPLSEKKGSGIGALGSGSDFTPFLQRYGIASSELGHKGGPKDA----VYHYHSIYDSF
TWQKK-FGDVGFHRHTDAAKVIGLLLLRLADGLILPLNTTQYTRDLEYYLEKVQDVS---
----------KIDLRTL----EIDFEPLADAIE--AAQTASGELDKQRHKALKKLHKLIG
KPAHGKYGIFKTMLRGCGWRVEEGKEVDYSLQTWEEGPKEGISSFPHPRLPFPLPTPGRI
REIKKVLKEIRII--NRKLQNFESGFLSQDG----------------------LKDREW-
YKHKGTAPG------LWLGYGATTFPALTEAITI------------------DHSPKLAQ
KEVHELAKMINKIAKYLVA-----------------
>gi|70999674|ref|XP_754554.1|	Aspergillus fumigatus
---------------------------------------------------MGNDKKFEY
ESLPIPSYEEAISSRPSSSRSHLGPDEASDDAERQGLLH------NADNTSGPGGPRSRP
HGYQPPTVESVRNSLDDLASSGTDSARGSLEELQRELAQMDVEEAGVQSSSRRS------
------------RLGQHFSKRFNSLSRTLSAIQFPFRRFLPNFRFTINLDGARPR-FQDH
S-CIIMLRVFGLLLVVALVYVFFFSNLF---------NLNSRFMMGQSYSA---------
---------ASVQNFLQGHINETNIADNLRKVTK---FPHMAGTEGSFALAEWIEQEFK-
-NAGLD---------------------------EIEMEEFQVYLNYPN-EGGRRVAIVDP
PG-MAWEAALEEKN----------EQTMVFHGHSKSGNVTGHLVYANYGSRED----FQL
L-ADQGI-DMKGAIALVRYYGSETDRALKVKLAEMAGAAGCIIYSDPHED----------
------------------------GFRRG-PA------------FPDGRFMPDDGVQRGA
VSLMSWVVGDVLSPGFASTP---QEKKRLSIEESPGLPGIPSIPIAWRDAQRLLQVLKGH
GTKVP-KE--WVGGV-PEVQEWWTGDG------GSPKVNLMNI-LDEVERQPIYNVVGRI
IGLEQPEKKVIVGNHRDSWCL-GSADPGSGTAVFLELVRVFGELRTFG-WRPL-------
-----RTIEFVSWDAEEYNMIGSTEHVEKAIEALRENAFAYLNVDVGVTGN-NFDASGSP
LFQRIV-----MQILGRIADP----IT---NET--LKD-------IW-------------
------ERAQKKFSPLGSGSDYVAFQDIAGTSSVDFGFTGER-------FP-YHSCYENY
DWMTK-FGDPGFQYHKALGQFWALLLIDLADNPILQFDLQVYADHVHTYVTDLVAYAKSK
NVPVAPQLLEDRAVGEA----SVSFQPLFDAAS--KFKSDAEEFDQWAQLWHDTVWGA--
------------------------------------------------------------
GGFENNVMAIQRLSHNSRLASFDTQLLDLDHDGGVSTLPSHITSVPDTDSFRQIPNRTQ-
FKHVIFGPQ------LWSGYDAAVFPAIRDSID-------------------SGNWTLTQ
EWIDRVAKIIHRASNSLVHN----------------
>gi|109108238|ref|XP_001096141.	Macaca mulatta
------------------------------------------------------------
--MSGLDPCLTIGNFEKSHFWERLYPTVVGGGRAVEQQH--RRGSREAD-----------
------------------------------------------------------------
----------------------------------SARAKRWNLLHETDSAVATAR-RPRW
L-CAGALVLAGGFFLLGFLF-----GWF---------IKSSSEATNITPKHN--------
------------MKAFLDELKAENIKKFLHNFTQ---IPHLAGTEQNFQLAKQIQSQWK-
-EFGLD---------------------------SVELTHYDVLLSYPNKTHPNYISIINE
DGNEIFNTSLFEPPPAGYENVS--DIVPPFSAFSPQGMPEGDLVYVNYARTED----FFK
LERDMKI-NCSGKIVIARY-G-KVFRGNKVKNAQLAGATGVILYSDPADY----------
-------------------------FAPGVKS------------YPDGWNLPGGGVQRGN
ILNLNG-AGDPLTPGYPAN----EYAYRRGMAEAVGLPSIPVHPIGYYDAQKLLEKMGG-
-SASPDSS--WRGSL---KVPYNVGPGF--TGNFSTQKVKMHI-HSTSEVTRIYNVIGTL
RGAVEPDRYVILGGHRDSWVF-GGIDPQSGAAVVHEIVRSFGTLKKEG-WRPR-------
-----RTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTP
LMYSLV-----YNLTKELESP----DEGFEGKS--LYE-------SW-----------TK
KSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSSYPLYHSVYETY
ELVEK-FYDPMFKYHLTVAQVRGGMVFELANSVVLPFDCRDYAVVLRKYADKIYNISMKH
----------PQEMKTY----SVSFDSLFSAVK--NFTEIASKFSE-------RLRDF--
------------------------------------------------------------
DKSNPILL--RMM--NDQLMFLERAFIDPLG----------------------LPDRPF-
YRHVIYAPS------SHNKYAGESFPGIYDALFDIES-KVDP----------SQAWGEVK
RQISIATFTVQAAAETLSEVA---------------
>gi|47522828|ref|NP_999166.1|	Sus scrofa
---------------------------------------------------------MMD
QARSAFSSLFGGEPLSYTRFSLARQVDGDNSHVEMKLAA--DEEENVDSNTR--------
------------------------------------------------------------
-----------------------------------------SNHIGVAKPKRLNG-YVCY
G-IIAVITFFLIGFMIGYLA---YCKRVESKT-----DCKTLVPTEPSETEETETFEAEN
FPQTPRLFWADLKILLSKGLDTTDFTRTIKMLNE-DYAPREAGSQKDESLGFFIENQFR-
-EFKLS---------------------------KVWHDEHFVKIQVKGSNAENSVTLVNT
DSNSLVYPV---------------ESPEGYVAYSKATTVTGKLIFANFGTKKD----FED
L----KM-PVNGSLVIVRA-G-KITFAEKVANAQSLDAIGVLIYMDRANF----------
------------------------------------------------PIINADVPVFGH
AHLG---TGDPYTPGFPSF-----NHTQFPPSQSSGLPNIPVQTISRAGAEKLFGNMEQ-
--DCP-LT--WRTDF---PCKLVSSPS---------KNVKLTV-NNVLKEIKILNIFGVI
KGFEEPDRYVIVGAQRDAWGP-GAAKSSVGTSLLLNLAQILSDMVIKGQFKPS-------
-----RSIVFASWSAGDFGAIGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASP
LLYSLI-----EKMMQDVKNP----VT---GQS--LYR-----DSNW-------------
---------INKVEKLSFDDAAFPFLAYSGIPAVSFCFCEDTD------YPYLGTTMDTY
DVLSK-RVPQLNRMARAAAEVAGHLVIKLTIDFELNLNYEMYNDKILSFVREMNQF----
----------RVDIREM----GLSLQWLYSARG--DFFRATSRLTS-------DYRNV--
------------------------------------------------------------
ETRDKFVM--REI--NDRIMKVEYHFLSPYV----------------------SPRESP-
FRHIFWGSG------SH------TLSALVEHLKLRQK-NSS-----------AFNQTLLK
NQLALATWTIQGAANALSGDIWDIDNEF--------
>gi|47227995|emb|CAF97624.1|	Tetraodon nigroviridis
------------------------------------------------------------
---------FNGEPHSYTRFNLTQNMEGENSQVEMKLST--EDEEVGGNGVGE-------
------------------------------------------------------------
----------------------------------HLNHNSARLPSIAQRLGRTPK-NLCC
L-AATGLLVFIIGSLIGYLV---QSRKAPN-------CLPKALGFEDTLPHEDNVIPLMD
--------WEAVKTILNAKVSKDNFEMLFADLSS---SSHQAGSPGDETLANKVLSKFK-
-DYGMK----------------------------TWSDEHFVKVQDPPRSGFNSIVFKDG
NE----------------------ERPSGFLSYSACGRVMGAVLYGHYGQESD----LMM
L-QNKNL-DLSGRVLLLRA-G-RNSFAEKVANAAKLNASAVLIYPDPADY----------
-------------------------------------------------ALQDTTELFGH
VHLG---SGDPYTPGFPSF-----NHTQFPPVVSSGLPKIPAQTITAGMASKILRQLGG-
-PVVP-AG--WTGAL-------RLGDE--------KDIITMEV-SNVLTEKKISNVFGVI
KGIVDSDRYLVIGAQRDAWGS-GFAKSTVGTSVLLELARSISEMMKEG-FKPR-------
-----RSILFASWSAGEYGSVGATEWLEAYLSSLSMKAFSYINLDSVIAGQSGFKVAASP
LMHSVV-----VGALKEVHYS----NP---DRT--LYD--RFTRSNW-------------
--------ESDILEPLKLDNAAYPFLAFSGIPSVSFGFTSGYKE-----YPYFGTLLDTK
DSLEKATNNQVHHLAQTVTRFAGHMALRLVHDHLLRVDLTKYDKVIRSAVSQINMKVKEI
----------KRVTAASALPRSLDGPVADLASG--AYSRASRSLAA-------DIKNS--
------------------------------------------------------------
NLDDIEMC--RTI--NDRIMAVERNFLSPYV----------------------SPRERP-
FRHILLGSG------PH------TLKGLRDHLDSFQT-NSP-----------EADADLFR
NQFALATWTIQGCANSLAGNF---------------
>gi|126309327|ref|XP_001371634.	Monodelphis domestica
--------------------------------------------------MGFYPSTPLL
TSRSLCSQPQDLSSHHPYIIYKQEEEENQGKQLEEDEIQ--EEEEDSAALIMDMELRAT-
------------------------------------------------------------
----------------------------------NQQGRKWGKH---RRQNLTPK-IVTY
F-ILINLLIFIVAFLLGYIA---FRGSCQS-------CKVSVSEVNDDLGYELAPETSGS
-----TLYWADLREMFHKYLDEEHLKSSIRTISL---LERSSGSPGMTTLSYQIRDMFY-
-QQKLD---------------------------HVWIDTHYVGLQFPDPAQPNTLHWIDG
SGNISGELQL--------------EDPDVYCPYSAKGSAIGGLIYANYGHLKD----MLA
L-QEKGL-DPKGHLLLVRI-G-HMSFAEKVSNAEAFGALGVLIYPDPADI----------
---------------------------------------------HKKLRLSNHTAVYGH
VHLG---TGDPYTPGFPSF-----NQTQFPPVESSGLPSIPVQPISANMAAQLLRKLSG-
-PKAP-SE--WKGTL--SDTQYRLGPG---------PTLRLIV-NNHRASTPIISIFGCI
EGRSEPDHYIVIGAQRDAWGP-GAAKSAVGTAILLELVRTFSAMVRNG-FQPR-------
-----RSLLFISWDAGDFGNVGATEWLEGYLTMLHLKAAVYVSLDNAVLGDDQFHAKTSP
LLTSLI-----KSILKQVDSP----NHS--GQT--LYDQVVITGQSW-------------
--------EAEVIQPLPMDSSAYSFTAFGGVPAVEFSFTEEGPP-----YPFLNTKEDTF
ENLHGALQGRLPAVARAVAMVVGQLLIRLSQDRLLPLDFGCYGDVILKHIGRLNEF----
----------SGDLKAR----GLTLQWIYSARG--DYIRSAEKLQK-------EIYSS--
------------------------------------------------------------
EESNERLM--RMY--NVQIMRVEFYFLSQYV----------------------SPAIYP-
FRHIFLGQG------NH------TLRALLEHLQLLRD-EGTGDSSLRYSRP-HFEEGLLR
RQLALLTWTLQGAANALSGDVWNIDNNF--------
>gi|4758398|ref|NP_004467.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MWNLLHETDSAVATAR-RPRW
L-CAGALVLAGGFFLLGFLF-----GWF---------IKSSNEATNITPKHN--------
------------MKAFLDELKAENIKKFLYNFTQ---IPHLAGTEQNFQLAKQIQSQWK-
-EFGLD---------------------------SVELAHYDVLLSYPNKTHPNYISIINE
DGNEIFNTSLFEPPPPGYENVS--DIVPPFSAFSPQGMPEGDLVYVNYARTED----FFK
LERDMKI-NCSGKIVIARY-G-KVFRGNKVKNAQLAGAKGVILYSDPADY----------
-------------------------FAPGVKS------------YPDGWNLPGGGVQRGN
ILNLNG-AGDPLTPGYPAN----EYAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGG-
-SAPPDSS--WRGSL---KVPYNVGPGF--TGNFSTQKVKMHI-HSTNEVTRIYNVIGTL
RGAVEPDRYVILGGHRDSWVF-GGIDPQSGAAVVHEIVRSFGTLKKEG-WRPR-------
-----RTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTP
LMYSLV-----HNLTKELKSP----DEGFEGKS--LYE-------SW-----------TK
KSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETY
ELVEK-FYDPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKH
----------PQEMKTY----SVSFDSLFSAVK--NFTEIASKFSE-------RLQDF--
------------------------------------------------------------
DKSNPIVL--RMM--NDQLMFLERAFIDPLG----------------------LPDRPF-
YRHVIYAPS------SHNKYAGESFPGIYDALFDIES-KVDP----------SKAWGEVK
RQIYVAAFTVQAAAETLSEVA---------------
