>gi|149536980|ref|XP_001518410.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MAETK---YMQRLQGIA----------------------------
--VFSAWLAQVA----------------D---------------------------LRYL
LEQDFPG-----MRI--GPEPTTDSFIAVMY--------GDTEGSTPGNALVVDPKKPFR
KLSRFGNAFL------------NRFM-----CSQLPNQVLKSISIIDSPGILSGEKQRLS
RAFTTCQVLGRWFAERVDRIIL--LFDAHKLDI-----SDEFSEAIKAFRGQDDKIRVVL
NKADQVDTQQLMR-VYGALMWSL----GKVINTPEVLRVYIGSFWAQ---PLQNTDNRRL
FEVEA-------QDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIIS----HLKKEMP
-AVFGKENKKRELICRLPE--IYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKP
KLIEAVDNMLSHKISSLMNLISQEEI--------------SLPAQLVHGGAFDGT---SE
GPFNQGYGEGA----KEGADEE-EWVVAKDKPVYDELFY--------ALSPVD-GKISGV
NAKREMVTSKLPN-SVL--------------------GKIWKLAD---CDSDGMLDEEEF
ALAKHLIKIKLDGYELPSCLPPH------LVPPSHRMLWSSPFFWSFGFWAPGCRFQLIL
RAPISADPCCFPSWVAREKPGRQGRKRSAHGPRDRFSRADVRCRALVCSVPALGPSHRPP
SCEAAERLGPEGRRRGRSKVARRRERSRPGPAAGPDLSPLGPPSFTASVVRHLRPPPGS
>gi|72113270|ref|XP_790578.1|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MFTWLNNDES-R-----RKQP-QVFNNV-----------------
---------------LDGLKDM-YKKVIFPLEDEY-------------------------
--RFSEFHSPSL----------------DEADFTA--KPMILLVGQYSTGKTT--FIRYL
LEQEFPG-----MRV--GPEPTTDRFIAVMK--------GETDQVIPGNALVVDPKRQFR
KMSKFGNAFL------------NRFQ-----CSLTNCPVLDSITIIDTPGILSGEKQRLD
RGYDFVNVL-EWFAERADRIIL--LFDAHKLDI-----SDEFRRCIEAIKSQDEKIRIVL
NKSDMITHQQLMR-VYGALMWSL----GKVINTPEVSRVYIGSFWNK---PLHHDMNRKL
FEAEE-------VDLFSDLQSLPRNAALRKLNDLIKRARLAKVHAYVMS----ILKRDMP
-SMFGKDAKKKELINNLPE--VYKEVERTYQISPGDFPSLSRMREVLKDMDFTKFHTLKP
RMIEKVDLMLSNDMTRLMQMIPTEEA--------------LDKKQLIRGGAFVAD---EA
GPFGMGYGEGA----DFGKNEIQTWVVEDKMDEYEKVFN--------SLGPIE-NKVSGT
VAKKHMIKSKLPN-ISL--------------------GRIWKLAD---VDRDGMLDREEF
GLCLHLISIKVEGHELPSELPWH------LVPPSKR------------------------
--------------------GFSGHDPQ--------------------------------
-----------------------------------------------------------
>gi|125774399|ref|XP_001358458.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MFSFLKREQKNQ----------EVVENV-----------------
---------------IGELKKI-YRSKLLPLEEHY-------------------------
--QFHDFHSPKL----------------EDPDFDA--KPMILLVGQYSTGKTT--FIRYL
LERDFPG-----IRI--GPEPTTDRFIAVMY--------DDKEGVIPGNALVVDPKKQFR
PLSKYGNAFL------------NRFQ-----CSSVASPVLNAISIVDTPGILSGEKQRID
RGYDFTGVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFRRSIEALKGHDDKIRIIL
NKADMIDHQQLMR-VYGALMWSL----GKVLQTPEVARVYIGSFWDQ---PLRFDSNRRL
FEDEE-------QDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAFIIA----ELRKDMP
-SVFGKDSKKKDLIKNLGQ--VYDRIQREHSISPGDFPDIKKMQDVLQHQDFTKFHSLKP
HLLDIVDNMLAKDIARLMEMIPQEEM-------------TLVNEPIVKGGAFEGVIDDHV
SPFGYMKGEGI----DAGYGEH-EWICNKEKSRTDTIFN--------GLNPVD-GKISGA
TAKQELIKSKLPN-SVL--------------------SKIWKLSD---VDGDGFLDSEEF
ALALHLINVKLEGCELPTVLPEH------LVPPSKR------------------------
--------------------Y---------------------------------------
-----------------------------------------------------------
>gi|109105844|ref|XP_001118235.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MIPGILSQREDGTWGTAGAARSQGTKALGTGCLVE
PSRGGVGGPRCWKARRPTDRRRLTPAPRLPNRSTFASLHTRGGAKQVRLPRHPDHSLARF
GISQWEVGEGKTWHKPLREERAPFGRGRFGWLRCAPAQCGSLLVPCPGLRRLGSAPTPRS
QPPLCPAAASPVSGSMFSWVSKDAR-R-----KKEP-ELFQTV-----------------
---------------AEGLRQL-YAQKLLPLEEHY-------------------------
--RFHEFHSPAL----------------EDADFDN--KPMVLLVGQYSTGKTT--FIRHL
IEQDFPG-----MRI--GPEPTTDSFIAVMH--------GPTEGVVPGNALVVDPRRPFR
KLNAFGNAFL------------NRFM-----CAQLPNPVLDSISIIDTPGILSGEKQRIS
RGYDFAAVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFSEVIKALKNHEDKIRVVL
NKADQIETQQLMR-VYGALMWSL----GKIINTPEVVRVYIGSFWSH---PLLIPDNRKL
FEAEE-------QDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIIS----SLKKEMP
-NVFGKESKKKELVNNLGE--IYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKP
KLLDTVDDMLANDIARLMVMVRQEES--------------LMPSQVVKGGAFDGT---MN
GPFGHGYGEGA----GEGIDDV-EWVVGKDKPTYDEIFY--------TLSPVN-GKITGA
NAKKEMVKSKLPN-TVL--------------------GKIWKLAD---VDKDGLLDDEEF
ALANHLIKVKLEGHELPADLPPH------LVPPSKR------------------------
--------------------RHE-------------------------------------
-----------------------------------------------------------
>gi|73948077|ref|XP_541532.2|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MFSWLKRGGA-R-----GQQP-EAIRTV-----------------
---------------TSSLKEL-YRTKLLPLEEHY-------------------------
--RFGAFHSPAL----------------EDADFDG--KPMVLVAGQYSTGKTS--FIQYL
LEQEVPG-----SRV--GPEPTTDCFVAVMH--------GDTEGTVPGNALVVDPDKPFR
KLNPFGNTFL------------NRFM-----CAQLPNQVLESISIIDTPGILSGAKQRVS
RGYDFPAVL-RWFAERVDLIIL--LFDAHKLEI-----SDEFSEAIGALRGHEDKIRVVL
NKADMVETQQLMR-VYGALMWAL----GKVVGTPEVLRVYIGSFWSQ---PLLVPDNRRL
FELEE-------QDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIIS----YLKKEMP
-SVFGKENKKKQLILKLPV--IFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKP
KLLEALDEMLTHDIAKLMPLLRQEEL--------------ESTEVGVQGGAFEGT---HM
GPFVERGPDEALEDGEEGSDDEAEWVVTKDKSKYDEIFY--------NLAPAD-GKLSGT
KAKTWMVGTKLPN-SVL--------------------GRIWKLSD---VDRDGMLDDEEF
ALASHLIEAKLEGHGLPTNLPRR------LVPPSKR------------------------
--------------------RHKGSAE---------------------------------
-----------------------------------------------------------
>gi|156230367|gb|AAI51859.1|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------SHKRIQVRSQRRRRQSDTRTAGQWTVLCQHSRQIKEKTLERFSIPSIHKRGT
RVASSIKEDCKNNDNMFTWVNKEQGGR-----NKEG-DMFQTV-----------------
---------------TEGLQSL-YTKKLLPLEETY-------------------------
--LFHDFHSPAL----------------EEADFQS--KPMVLLVGQYSTGKTT--FIRYL
LEQDFPG-----MRI--GPEPTTDGFIAVMY--------NDNEGVVPGNALVVDPKKPFR
KLNSFGNSFL------------NRFI-----CSQMPNQVLQSISIIDTPGILSGEKQRIS
RGYDFSEVL-RWFGERVDRIIL--LFDAHKLDI-----SDEFSEAIRAFRGQDDKIRVVL
NKADQVDTQQLMR-VYGALMWSL----GKVINTPEVVRVYLGSFWAK---PLQNAENRRL
FEAET-------QDLFRDIQGLPRNAALRKLNDLIKRARLAKVHAYIIS----YLKKEMP
-SLFGKEKKKEELIAHLPE--IYQILQREHHISPGDFPNVIKMQEQLQHYDFSKFPSMKV
KLIESVDRMLSTKISYLMNMIREEES--------------KQPPQMVKGGAFEDS---SD
GPFGHGYGEGV----SAGADTE-DWIVSRDKHRYDEIFY--------TLMPVN-GRVTGI
NAKKEMMNSRLPN-TVL--------------------GKIWKLAD---CDKDGMLDDEEF
ALAQHLIKIKLEGFDLPIELPNH------LVPPSHR------------------------
--------------------KNPTADILYNHQED--------------------------
-----------------------------------------------------------
>gi|126303668|ref|XP_001380724.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MYDQKRKRTGHMFSWLGHDDR-R-----RKDP-EVFQTV-----------------
---------------SEGLKKL-YKTKLLPLEEYY-------------------------
--RFHEFHSPAL----------------EDADFDN--KPMVLLVGQYSTGKTT--FIRYL
LEQDFPG-----MRI--GPEPTTDSFIAVMQ--------GDVEGIIPGNALVVDPKKPFR
KLNAFGNAFL------------NRFV-----CAQLPNPVLESISVIDTPGILSGEKQRIS
RGYDFAAVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFSEVIKALKNHEDKMRVVL
NKADQIETQQLMR-VYGALMWSL----GKIVNTPEVIRVYIGSFWSH---PLLIPDNRKL
FEAEE-------QDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIIS----SLKKEMP
-SVFGKDNKKKELVNNLGE--IYGRIEREHQISPGDFPNLKKMQDQLQAQDFSKFQPLKN
KLLEVVEDMLAHDIAQLMVLVRQEET--------------QRPVQMVKGGAFEGT---LH
GPFGHGYGEGA----GEGIDDA-EWVVARDKPMYDEIFY--------TLSPVD-GKITGA
NAKKEMVRSKLPN-TVL--------------------GKIWKLAD---IDKDGMLDDEEF
ALANHLIKVKLEGHELPNELPSH------LLPPSKR------------------------
--------------------KMAE------------------------------------
-----------------------------------------------------------
>gi|119919307|ref|XP_001256252.	Bos taurus
MGQAFRNGPGRTLTGPPAANRCESGPSLPGASALSLHFSSPEKGHHAPTTTWAHTAALFQ
NGGSRTRTHSAKCLSVSQREMGARTPCGSIAPASTCTAPSPALYPALPSSPPGVATPSSC
TRQEHCAEMGGPVGKLRPRLRGVENAHLAGVSAEPPTRLVPLVGPPFVSGALLRVLGIQR
PLEIAGAQWSLAVSLPCGCSRKGHRYVRLNASHQDLRGKGRVEGCTPSGHQQGAPRTASP
PSPGPSGHPPAPPRPDPSRSAGHSQHPARSGWSPVFSAHLTLIYDPGNEGADTGQGHMVP
ERGVPVTAQSGWLSADKGRGDEKECQGSRGEGRRQGRAVQTGGAWHPGFSPASGDSEWEK
EGSPLRELRWGAYSEYWGVQLGISRGRKTCKPWDVRAPHFGQPPSRPQHFREPPHKGRGE
TGAVATAPGPGQARVPLCRRALGRPCRTPAQCGPLPAPLPHRPLSRPARPSLGSASSLGS
QPPLCPAAASPVSSSMFSWVSKDAR-R-----KKEP-ELFQTV-----------------
---------------SEGLRQL-YAQKLLPLEEHY-------------------------
--RFHEFHSPAL----------------EDADFDN--KPMVLLVGQYSTGKTT--FIRHL
IEQDFPG-----MRI--GPEPTTDSFIAVMH--------GPTEGVVPGNALVVDPRRPFR
KLNAFGNAFL------------NRFM-----CAQLPNPVLDSISIIDTPGILSGEKQRIS
RGL---------------------------------------------------------
-------HQNMLK-----LLLSL-------------------------------------
-----------------------------------------------------HLA----
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>gi|91084005|ref|XP_975287.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MFSWLNQKAEVV-----H----ECYENV-----------------
---------------AEGLKSI-YKNKMLPLEQHY-------------------------
--LFEEFHSPPL----------------NDPDFES--KPLILLVGQYSTGKTT--FIKYL
LERDFPG-----MRI--GPEPTTDRFIAVMY--------GEKEGVIPGNALVVDPKKQFR
PLSAFGNSFL------------NRFQ-----CSLVNSPVLKGMSIIDTPGILAGEKQRID
RGYDFTGVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFRRSIEALRGHDDKIRIVL
NKADMIDHQQLMR-VYGALMWSL----GKVLQMPEVVRVYIGSFWDQ---PLRYDVNRRL
FEDEA-------QDLFKDLQSLPKNSALRKLNDLIKRARLAKVHAYIIA----ELRKEMP
-NVFGKDSKKKDLVKNLHE--IYVKIQKEHNISAGDFPDIQKMRDALARHDFTKFHSLKP
KLLDVVEQMLSDDIAQLMSMISHEVN--------------EINKSDVTGGAFENI-GDHS
SPFGYKRGEGV----NAGMGEP-DWIVNKERATFDAIFD--------QLSPNG-TKISGS
TAKIELVKSKLPN-SVL--------------------SKIWKLAD---VDKDGFLDRDEF
ALAMHLINVKVEGNDLPDVLPPH------LKPPLKK------------------------
--------------------MYP-------------------------------------
-----------------------------------------------------------
>gi|108873382|gb|EAT37607.1|	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MFSWLKRETKTE----------EVVENV-----------------
---------------LGELKKI-YKSKLLPLEEHY-------------------------
--SFHDFHSPKL----------------EDPDFDA--KPMILLVGQYSTGKTT--FIRYL
LERDFPG-----IRI--GPEPTTDRFIAVMY--------DDKEGMIPGNALVVDPKKQFR
PLGKYGNAFL------------NRFQ-----CSTVPSPVLRAISIVDTPGILSGEKQRVD
RGYDFTGVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFRRSIEALRGHDDKIRIVL
NKADMIDHQQLMR-VYGALMWSL----GKVLQTPEVARVYIGSFWDQ---PLRYDVNRRL
FEDEE-------QDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAFIIA----ELRKDMP
-SVFGKDSKKKDLIKNLGQ--VYDRIQKEHQISPGDFPDIKKMQEVLANQDFSKFHSLKI
PLLEVVDRMLATDIARLMNMIPQEEM-------------TMVSEPLIKGGAFDGV-EDVV
SPFGYRKGEGI----DAGCGEV-DWICNRDRERTDPIFE--------SLKPID-GKISGA
AAKSELIKSKLPN-NVL--------------------SKIWKLSD---YDQDGFLDIEEF
ALAMHLINVKMDGNELPTSLPSH------LVPPSKR------------------------
----------------------NGVAE---------------------------------
-----------------------------------------------------------
>gi|71895861|ref|NP_001025664.1	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MFSWMGKNEK-T-----KKSP-EVIHTV-----------------
---------------TEGLKDL-YKKKLKPVEDFY-------------------------
--RFHDFHSPAL----------------EDADFDN--KPMVLVVGQYSTGKTT--FIKYL
LEQDIPG-----SRI--GPEPTTDSFIAVMH--------GETEGVIPGNALMVDPNKPFR
KLNPFGNTFL------------NRFM-----CAHLPNKVLESISLIDTPGILSGAKQRVS
RGYDFPAVL-QWFAERVDRIIL--LFDAHKLEI-----SDEFSEAIRALKGNEDKIRVVL
NKADMVETQQLMR-VYGALMWSL----GKVFNTPEVLRVYIGSFWSE---PLMISDNRRL
FELEE-------QDLFQDIQNLPRNSALRKLNDLVKRARLVRVHAHIIS----HLKKEMP
-SVFGKDNKKKQLINKLPV--IFAKIQLEHHISPGDFPDCAKMQEQLAIHDFKKFHALKP
HMIDALDEMLTVDIAKLMPLLRQEDL--------------ETCDNVVQGGAFDGT---HN
GPFIEGSTDGI----FEGLDDE-EWVVTKDKPKYDEIFF--------NLAPTD-GKITGT
KAKNWMVTTKLPN-SVL--------------------GKIWKLSD---VDRDGMLDDEEF
ALASHLIEVKLEGHGLPPELPRH------LIPPSKR------------------------
--------------------RQKGSAE---------------------------------
-----------------------------------------------------------
>gi|156552834|ref|XP_001599894.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------MREIAARSYTLFTS
NKLQQRLRGGPLLKHILQHMKNGSTNEKLHLYGTHDVNIVNTLRAMGFVDELFKLDLGVS
LVYELRVIDGGQSQEVRGIKRLTYTSKLLPLEQAY-------------------------
--QFHDFHSPQL----------------DDPDFDA--KPMILLVGQYSTGKTT--FIKYL
LERDFPG-----IRI--GPEPTTDRFIAVMY--------DDKEGVIPGNALIVDPQKQFR
PLTKFGNAFL------------NRFQ-----CSTVNSPVLKGISIVDTPGILSGEKQRVD
RGYDFTGVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFRRSIEALRGHDDKIRIVL
NKADMIDHQQLMR-VYGALMWSL----GKVLQTPEVARVYIGSFWDQ---PLRYDVNRRL
FEDEE-------QDLFKDMRSLPRNAALRKLNDLIKRARLAKVHAYIIS----ALRKDMP
-SVFGKDNKKKELIKNLGQ--IYDQIQREQQISPGDFPDLKKMQENLAHHDFTKFNILKP
RLLEVVDKMLSDDIAKLMAMIPHEES-------------NTTSDPVIKGGAFEGV-EDQA
SPFGYKKGEGI----DAGSNEP-EWIVMKEKYKYDSLFE--------SLGPSD-GKITGA
AAKSEMVKSKLPN-TVL--------------------GKIWKLSD---VDKDGYLDSDEF
ALAMHLINVKLDGHEVPAELPSH------LIPPSKR------------------------
--------------------DLCHKA----------------------------------
-----------------------------------------------------------
>gi|149042663|gb|EDL96300.1|	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------MASSEVGAEEDAEDSKAEVDAETGEEAEDQGEPRPSLEAGSAREASEKSEDT
QSSEVRETEGQASGMSEEDLAEASSEEEGGEEDGRENGGLPSKEESGEDSGDGASSEEEG
STSGEAAEPQKTPRATGHEEEGAQLDVEDLNTGSEGVKTQDTEAEASEERQQGRGNPVIA
HQEEAEDVSEEAPMRDRSHIEKTLMLN-----EDKPADDYSAV-----------------
---------------LQRLRKI-YHTSIKPLEQSY-------------------------
--KYNELRQHEI----------------TDGEITS--KPMVLFLGPWSVGKST--MINYL
LGLEDTR-----YQLYTGAEPTTSEFTVLMH--------GPKLKTIEGIVMAADSARSFS
PLEKFGQNFL------------EKLI-----GIEVPHKLLERVTFVDTPGIIENRKQQ-E
RGYPFNDVC-QWFIDRADLIFV--VFDPTKLDV-----GLELEMLFRQLKGRESQIRIIL
NKADNLATQMLMR-VYGALFWSL----APLINVTEPPRVYVSSFWPQ---DYKPDTHRDL
FLKEE-------ISLLEDLNQVIENRLENKIAFIRQHAIRVRIHALLVDRYLQTYKDKMT
-FFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFDLPNREAYKDFFGINPISNF-----
-------KLLSQQCSYM-------------------------------GGCFLEK-----
----------------------------IERAITQELPS--------LLGSIGLGKNPGA
-----------PN-----------------------------------CDKTGC------
-----------------GETPKN-------------------------------------
--------------------RYKKH-----------------------------------
-----------------------------------------------------------
>gi|82136235|sp|Q90577|SRCA_CHI	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MKRLNLLCCCVASLLLL
GTAEEVEDASEPTKRDRSHLENTLKLN-----EDKPADDFSGV-----------------
---------------LQRLRKI-YHASIKPLEQSY-------------------------
--RYNELRQHEI----------------TDGEITS--KPMVLFLGPWSVGKSS--MINYL
LGLDDTP-----YQLYTGAGPTTSEFTVIMH--------GPKLKTIEGIVMAADSARSFS
PLKKFGQNFL------------EKLI-----GIELPHKLLERVTFVDTPGIIENRKQQ-E
RGYPFNDVC-QWFIDRADLIFV--VFDPTKLDV-----GLELEMLFRQLKGRESQIRIIL
NKADSLATQELMR-VYG-LFWSL----APLINVTEPPRVYVSSFWPH---EYHPDTHKDL
FLKEE-------ISLLEDLNQVIENRMENKIAFIRQHAIRVRIHALLVDRYLQTYKDKMT
-FFSDGELVFRDIVEDPDKFFIFKSILAKTNVSKFDLPQREAYKDFFGINPITSF-----
-------KLLSQQCSYM-------------------------------GGCYLEK-----
----------------------------IEKAITRELPD--------LLGSIG-------
----------------L--------------------GKKPNVLS---CDVTGCGET---
--------------------------------PKNR------------------------
--------------------YKKP------------------------------------
-----------------------------------------------------------
>gi|56754041|gb|AAW25211.1|	Schistosoma japonicum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MLSALKSSKP-------KDQ--EAYATV-----------------
---------------IEGLSKL-YFSKLLPLENAY-------------------------
--KFHDFHSPPL----------------EKSDFES--KPMVLLIGQYSTGKTT--FIRYL
IGEDFPG-----IRI--GPEPTTDSFIAVMN--------DVRRGIIPGNALVMDHSKQFR
PLSKFGNGFL------------NRFQ-----CAHMPNGVLEGITFIDTPGILSGEKQRVD
RGYDFSGVI-EWLAERADRIIL--LFDAHKLDI-----SDEFRRVIEVLKSNEDKIRIVL
NKADMIDSQQLMR-VYGALMWSL----GKILNTPEVARVYIGSFWDR---QLVFDTNRKL
FELEK-------MDLFRDLATLPANGTLRKLNDFIRRTRLAKVHAYVIS----YLKKEMP
-SMLGKDSKKKELINNLSK--VYDTISRTQKISIGDFPNINRMQEYLEVHDFKTFSALQP
KLIKVVDDMLANEVAKLVQMIPMERD-----------AIVETHGPAVTGGAFDTS----G
TPFSFHASEGF----EEGRFEN-DWIVNRFRQPWDEVFL--------ALNPMD-GKISGE
AARKHMLKSGLPN-STL--------------------RNIWILGD---VDRDGCLDGDEF
ALVCYLMKLKLEGNELPPTLPAH------LIPPSKQ------------------------
-------------------NSNQIPRNGYHGD----------------------------
-----------------------------------------------------------
>gi|54038195|gb|AAH84280.1|	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------VAGCEEVTSAPLSDHVEE
AFVAGAVGRQERGSAMFSWTNTDTR-R-----KKEP-ELFQTV-----------------
---------------AEGLWKL-YSHKLLPLEETY-------------------------
--RFHEFHSPAL----------------EDADFHN--KPMVLLVGQYSTGKTT--FIRHL
LESDFPG-----MRI--GPEPTTDSFIAVMH--------APLQGVMPGNALVVDPKKPFR
KLSAFGNAFL------------NRFM-----CAQLPNPVLESISIIDTPGILSGEKQRIS
RGYDFAAVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFSDVIKALKNHEDKIRVVL
NKADQIETQQLMR-VYGALMWSL----GKIINTPEVVRVYIGSFWSH---PLLIPDNRKL
FEAEE-------QDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIIS----AIKKEMP
-NVFGKENKKKELINNLHE--IYMKIEKEHQISPGDFPNIKKMQEILMTQDFTKFQALKP
KLLDTVDDMLASDIAKLMVMVQQEES--------------QKTNQVVKGGAFEGT---RN
GPFGHGYGEGA----GEGIDDF-DWVVGKDKPTYDEIFF--------TLSPVN-GKVTGA
SAKKEMVKSKLPN-TVL--------------------GKIWKLAD---VDRDGLLDDEEF
ALANHLIKIKLEGHELPTDLPSH------LVPPSKR------------------------
--------------------RGE-------------------------------------
-----------------------------------------------------------
>gi|47223095|emb|CAG07182.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--LDPGNTGRISAGDAAQFLKTSGLSD-----TTLG-NVAMLI-----------------
---------------IEGNKTF-VPHELLPSQGFFVALRLVASAQSGNEISLNNLNQNLA
APKFRDTSSPVLSVSKPGSDSLWAIRLEEKGKFEGTFESLSPVNGLLSGDKVKPVLINSK
LPLDVLGKIWDLSDIDKDGHLDKDEFTVAMHFVYRAMEKEPVPTSLPNS--LIPPSKRKK
PAGALPGAVAVLPSVPGFMAPSGSFK-----ESPRSTPPLNKAPLLSTSTVSLSPKHSF-
RSTSEPAV--NWVVSVADRERYDELFRKTDTDGDGFINGTEVIEIFMLSSLSQTMLAQIW
GLADTKQTGKLNREQFSLAMYLIEQKTNKGIDPPSTLTPDMIPPSERIAASAVVPDSGSS
TGSAELTGNKELDDLSQEIAQLQREKFILEQEIMVKEGAIRHQNGEVQD-MQTGLDRESS
-SLMDLETQKQLAQERLEE--MDQQHSKLDGMLSDVKQKCQEESHKISSLH-SQIRSQES
DVRSQEDELGRSKVE--LSQLQEEEA--------------QLEQSLLSGRVQLDS---II
KSLKTT---------QEEINQDTQKEVTKTTEQYNSALT--------SINGGS-------
-------LSNLPD-----------------------------LSDDISEKESGAFRNVGD
SFKSKIAMFNNKSVKEPPADPFH------TEDPFKSF-----------------------
----------------SAKDIHKVNTFFLKNVHFCCRSIWRRSFQRKRSLQRDLI-----
-----------------------------------------------------------
>gi|157016524|gb|EAA10568.4|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------FPLTPSNMFSWLKRETKTE----------EVVENV-----------------
---------------LGELKKI-YRSKLLPLEEHY-------------------------
--NFHDFHSPKL----------------EDSDFDA--KPMILLVGQYSTGKTT--FIRYL
LERDFPG-----IRI--GPEPTTDRFIAVMY--------DDKEGMIPGNALVVDPKKQFR
PLEKYGNAFL------------NRFQ-----CSHVPSPVLRAISIVDTPGILSGEKQRVD
RGYDFTGVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFRRSIEALRGHDDKIRIVL
NKADMIDHQQLMR-VYGALMWSL----GKVLQTPEVARVYIGSFWDQ---PLRYDVNRRL
FEDEE-------QDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAYLIS----ELRKEMP
-QIFGKDSKKKELIKNLGT--IYDRVCREHQVSIGDLPDIKKMQEVLANQDFTKFHSLKM
PLIEVVDRMLAVDIARLMSMIPQEEM-------------QLVSEPLVKGGAFDGV-EDVV
SPFGYRKGEGI----DAGYGEV-DWICNRDRARTDPIFE--------SLGPVD-GKISGA
AAKSELIKSKLPN-NVL--------------------SKIWKLSD---YDQDGFLDIEEF
ALAMHLINVKMDGNELPTALPLH------LVPPSKR------------------------
--------------------RVD-------------------------------------
-----------------------------------------------------------
>gi|67967647|dbj|BAE00306.1|	Macaca fascicularis
------------------------------------------------------------
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---------------MFSWLKRGGA-R-----GQQP-EAIRTV-----------------
---------------TSALKEL-YRTKLLPLEEHY-------------------------
--RFGAFHSPAL----------------EDADFDG--KPMVLVAGQYSTGKTS--FIQYL
LEQEVPG-----SRV--GPEPTTDCFVAVMH--------GDTEGTVPGNALVVDPDKPFR
KLNPFGNTFL------------NRFM-----CAQLPNQVLESISIIDTPGILSGAKQRVS
RGYDFPAVL-RWFAERVDLIIL--LFDAHKLEI-----SDEFSEAIGALRGHEDKIRVVL
NKADMVETQQLMR-VYGALMWAL----GKVVGTPEVLRVYIGSFWSQ---PLLVPDNRRL
FELEE-------QDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIIS----YLKKEMP
-SVFGKENKKKQLILKLPV--IFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKP
KLLEALDEMLTHDIAKLMPLLRQEEL--------------ENTEVGVQGGAFEGT---HM
GPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFY--------NLAPAD-GKLSGS
KAKTWMVGTKLPN-SVL--------------------GRIWKLSD---VDRDGMLDDEEF
ALASHLIEAKLEGHGLPANLPRR------LVPPSKR------------------------
--------------------RHKGSAE---------------------------------
-----------------------------------------------------------
>gi|119604948|gb|EAW84542.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------MAAPLIPLSQQIPTGNSLYESYY
KQVDPAYTGRVGASEAALFLKKSGLS-----------DIILGK-----------------
---------------IWDLADP-EGKGFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMP
PPKFHDTSSPLM-VTPPSAEAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSK
LPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPS--LIPPSK--R
KKTVFPGAVP------------VLPASPPPKDSLRSTPSHGSVSSLNSTGSLS-PKHSLK
QTQPTV----NWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIW
ALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSER---GTPGPDSSGS
LGSGEFTGVKELDDISQEIAQLQREKYSLE-QDIREKEEAIRQKTSEVQELQNDLDRETS
-SLQELEAQKQDAQDRLDE--MDQQKAKLRDMLSDVRQKCQDETQMISSLK-TQIQSQES
DLKSQEDDLNRAKSE--LNRLQQEET--------------QLEQSIQAGRVQLET---II
KSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAE
RGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGAD---PFKGDPFQNDPF
AEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTK------------------------
--------------------NDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDP
FGTLDPFGSGSFNSAEGFADFSQMSKVKVHL----------------------------
>gi|114678112|ref|XP_001169733.	Pan troglodytes
------------------------------------------------------------
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---------------MFSWLKRGGA-R-----GQQP-EAIRTV-----------------
---------------TSALKEL-YRTKLLPLEEHY-------------------------
--RFGAFHSPAL----------------EDADFDG--KPMVLVAGQYSTGKTS--FIQYL
LEQEVPG-----SRV--GPEPTTDCFVAVMH--------GDTEGTVPGNALVVDPDKPFR
KLNPFGNTFL------------NRFM-----CAQLPNQVLESISIIDTPGILSGAKQRVS
RGYDFPAVL-RWFAERVDLIIL--LFDAHKLEI-----SDEFSEAIGALRGHEDKIRLVL
NKADMVETQQLMR-VYGALMWAL----GKVVGTPEVLRVYIGSFWSQ---PLLVPDNRRL
FELEE-------QDLFRDIQGLPRHAALRKLNDLVKRARLVRAHAYIIS----YLKKEMP
-SVFGKENKKKQLILKLPV--IFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKP
KLLEALDEMLTHDIAKLMPLLRQEEL--------------ESTEVGVQGGAFEGT---HM
GPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFY--------NLAPAD-GKLSGS
KAKTWMVGTKLPN-SVL--------------------GRIWKLSD---VDRDGMLDDEEF
ALASHLIEAKLEGHGLPANLPRR------LVPPSKR------------------------
--------------------RHKGSAEGPHGKDGEEQNTWRRRTLQDARWDSQAHHCPPP
HGWEGPLNGTVSPQSE-------------------------------------------
>gi|24646379|ref|NP_731737.1|	Drosophila melanogaster
------------------------------------------------------------
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---------MPRPEAGDSFLKREKNTQ----------EVVENV-----------------
---------------IGELKKI-YRSKLLPLEEHY-------------------------
--QFHDFHSPKL----------------EDPDFDA--KPMILLVGQYSTGKTT--FIRYL
LERDFPG-----IRI--GPEPTTDRFIAVMY--------DDKEGVIPGNALVVDPKKQFR
PLSKYGNAFL------------NRFQ-----CSSVASPVLNAISIVDTPGILSGEKQRID
RGYDFTGVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFRRSIEALKGHDDKIRIIL
NKADMIDHQQLMR-VYGALMWSL----GKVLQTPEVARVYIGSFWDQ---PLRFDANRRL
FEDEE-------QDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAFIIA----ELRKDMP
-SVFGKDSKKKDLIKNLGQ--VYDRIQREHSISPGDFPDIKKMQEVLQHQDFTKFHSLKP
HLLDIVDNMLAKDIARLMEMIPQEEM-------------TMVADPIVKGGAFEGVIDDHV
SPFGYMKGEGI----DAGYGEH-EWICNKDKPRTDGIFN--------GLGPVD-GKISGA
TAKQELIKSKLPN-SVL--------------------SKIWKLSD---VDGDGFLDSDEF
ALALHLINVKLEGCELPTVLPEH------LVPPSKR------------------------
--------------------YD--------------------------------------
-----------------------------------------------------------
>gi|26331648|dbj|BAC29554.1|	Mus musculus
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
-------------------------------------MAAPLVPLSQQIPGGNPLYESYY
KQVDPAYTGRVGASEAALFLKKSGLS-----------DIILGK-----------------
---------------IWDLADP-EGKGFLDKQGFYVALRLVACAQSGHEVTLSSLSLTMP
PPKFHDTSSPLM-ATQSSAETHWAVRVEEKAKFDGIFESLLPVNGLLSGDKVKPVLMNSK
LPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSILPPP--LIPPSK--R
KKTVFAGAVP------------VLPASPPPKDSLRSTPSHGSVSSLNSTGSLS-PKHSVK
Q----PPV--AWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIW
ALADTRQTGKLSKEQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSER---GTPIPDSSST
LASGEFTGVKELDDISQEIAQLQREKYSLE-QDIREKEEAIRQKTSEVQELQNDLDRETS
-SLQELEAQKQDAQDRLDE--MDQQKAKLRDMLSDVRQKCQDETQTISSLK-TQIQSQES
DLKSQEDDLNRAKSE--LNRLQQEET--------------QLEQSIQAGRAQLET---IL
RSLKCTQDDINQARSKLSQLQESHLEAHRSLEQYDQVPD--------GVSGTS-------
----------LPDLATL--------------------NEGILLAE-----RGGF------
---GAMVKVE--------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>gi|66510064|ref|XP_396463.2|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
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------------------------------------------------------------
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------------------------------------------------------------
---------------MFSWLTREES-------GKQ--DLFENV-----------------
---------------ADGLKKI-YKSKLLPLEQHY-------------------------
--QFHDFHSPQL----------------DDPDFDA--KPMILLVGQYSTGKTT--FIKYL
LERDFPG-----IRI--GPEPTTDRFIAVMY--------NEKEGVIPGNALVVDPNKQFR
PLSKFGNAFL------------NRFQ-----CSTVASPVLKGISIVDTPGILSGEKQRVD
RGYDFTGVM-EWFAERVDRIIL--LFDAHKLDI-----SDEFRRLIEALRGHDDKIRIVL
NKADMIDHQQLMR-VYGALMWSL----GKVLQTPEVARVYIGSFWDQ---PLRYDVNKRL
FEDEE-------QDLFKDMQSLPKNAALRKLNDLIKRARLAKVHAYIIS----ALRKDMP
-SVFGKDTKKKELIKNLGQ--IYDQIQREQQISPGDFPDLKKMQEFLAHHDFSKFNTLKP
KLLEVVDNMLVKDIAQLMSMIPHEEI-------------GTTSDLFVKGGAFEGV-VDQV
SPFGYKRGEGI----DAGAGEP-EWIVNKERYKYNAIFE--------KLGPCD-GKITGA
AAKSEMVKSKLPN-NVL--------------------GRIWKLSD---IDKDGFLDSDEF
ALAMHLINVKLEGYDLPAELPDH------LIPPSKR------------------------
--------------------NA--------------------------------------
-----------------------------------------------------------
>gi|7106303|ref|NP_034249.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MFSWVSKDAR-R-----KKEP-ELFQTV-----------------
---------------AEGLRQL-YAQKLLPLEEHY-------------------------
--RFHEFHSPAL----------------EDADFDN--KPMVLLVGQYSTGKTT--FIRHL
IEQDFPG-----MRI--GPEPTTDSFIAVMH--------GPTEGVVPGNALVVDPRRPFR
KLNAFGNAFL------------NRFM-----CAQLPNPVLDSISIIDTPGILSGEKQRIS
RGYDFAAVL-EWFAERVDRIIL--LFDAHKLDI-----SDEFSEVIKALKNHEDKIRVVL
NKADQIETQQLMR-VYGALMWSL----GKIINTPEVVRVYIGSFWSH---PLLIPDNRKL
FEAEE-------QDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIIS----SLKKEMP
-NVFGKESKKKELVNNLGE--IYQKIEREHQISSGDFPSLRKMQELLQTQDFSKFQALKP
KLLDTVDDMLANDIARLMVMVRQEES--------------LMPSQAVKGGAFDGT---MN
GPFGHGYGEGA----GEGIDDV-EWVVGKDKPTYDEIFY--------TLSPVN-GKITGA
NAKKEMVKSKLPN-TVL--------------------GKIWKLAD---VDKDGLLDDEEF
ALANHLIKVKLEGHELPADLPPH------LIPPSKR------------------------
--------------------RHE-------------------------------------
-----------------------------------------------------------
