>gi|91077778|ref|XP_969102.1|	Tribolium castaneum
----------------------------MKMTLSSTNGTTNEKL----------------
-------TTPTENKQGSPNSSPRA--SPRPSPRPQPKREHPKS-ETHLTVNYKEI-PGSN
KHDGSPSSQESSVSSRASNLDISPPSNLKVESTSSSNKERKDP--RGKKKSSWFNPF---
---YPTYKSRSEDFKRIFK---DVPDDERLLVDYSCAL-QKEILAQGRLYVTQNYLCFYA
NILGWETTLKLKWKDVSAITKEKTAIV---IPNAVLICTRTE-KYFFTSFVARDKTYLML
FRVW-QNALMDQPMSPQEMWQWVHQWYGEELGLTSDD-EDYVAPGTEEDKL--SARLSVE
SFSEHESS---AVENPLEAMVVEEKPPQDDDSVT-NRPVDRRRTTSSHLPTDYSDTT---
-ESDGEKQTKTKPTF-----FLSWDKSSPFLHPSSPEYDDT--VPVLPNV-KCDTHVQ--
-----CTSTHEGRQIMNEIVPIHIDQLFTLLFT-SSK-FYLDFHASRKTTDLT-QTPWTH
NPSDNSKTRVVNLTVALTQAMGPKTAQVTETQVMLPCSKAGCLYAIDVDTVNAGIPYADS
FNIVVHHCLQKISETE-SSYQVF---AQVMYKKSVWGLVKGMIEKTCWSGLEDFYVSLAK
ALHV-----------EGEENVCDVKRKSRRKRRIHS------------------------
----------------------MPRPGVEDSRPLIGASSRISSG----------------
-----GIFSSDVATMIVFTV------LILLVVLNVMLYFKLWSLEESPPYTLL------D
LHVLK-DPPKTHDEWIKLLQQQETLHSVELQK--WQRVLKTAIQLLKQTEESLNELQRSI
NPSYSSKVMSIL----QNHKDTVEQNE-----------KSEL
>gi|66531802|ref|XP_394943.2|	Apis mellifera
--MYFEVESIQKYPTVTMNKSVEDLLISSREVMTNVNSTGFENQNPTMNIGNGISDNIQE
T------IIGGNGEKGSPVSSPNL--SPR------PSPKVRNK-RDHSKLNHDSN-TKES
--NSMNKLDEHQLHQQQDITNKSSDSSQAIKSSHEGKKETRSS--ERNKKKSWYHVL---
---YPTYKSRSDDFKRIFK---DVPDDERLVVDYSCAL-QREILVHGRLYVSQNYVCFYA
NIFSWETLVCLRWKDVTSITKEKTALV---IPNAILICTATD-KFFLTSFGARDKTYVML
FRVW-QNALIGEPMNAPELWQLVHSCYGDELGLTSDD-EDYVPPLPPADEEKLSTRLSVE
SFSEVESG-----------------------------------------NIEHSITGA--
-PDTIESKAEVHHLP------------RPDPTIDATDLSDTTESEAEKHALKLSVR----
-GTIVCTSPHEGRQIGKATFPIHIDQLFTLLFT-NSK-FFLDFQTARKTTDLV-QSAWTQ
NEQTGQKVRNLSFTIALSQAIGPRTSNISETQIMLPCSRPGYLYSIDVESVNAGIPYADS
FSVLIHYCITSISENE-TNMVIY---AQIKYKKNVWGFVKSVIEKNCWAGMDEYFTSLIK
ALTIEC---------EENNGSGGVKRKTRRRRRATG------------------------
-------------------------PGISLQTHSSDHTSSTLQNSLNLPHINDNTVS---
--AARGDSNMIISSMLLIAV-------LCLMVINGLLYYKLWGLEEAAAYTI--M----D
LHVLK-NTPKTEEDWIHLLQQQESLHNIEMRK--WQRVLHTAAQLLRQTEESLTELQMSI
HPTATEKMFSVLKPSLKSYNSHTEQRS-----------HSEM
>gi|125951943|ref|XP_001335624.	Danio rerio
MWFNKDAEIEFVTSESKRVKVSVSHGITPEEVLLANALWVSERANPYFILQRRKGHGRGG
GITGLLVGTLDVVLDSSARVAPYR--ILHQTGESQIFWNIACG-SSRKEITEHWE-WLEA
--NLLQTLSIFDNDDDITTFVKGKIQGIIAEENKGGKPQEDED-----------------
---PGKFREAELKMRKLF----GMPEEEKLVNYYPCSYWKGRVPRQGWIYLSVNHLCFYS
FLLGKEVSLVVQWTDVTQLDKNATLVF----PESIRVSTRDT-EHFFSMFLNINETFKLM
EQLA--------------------------------------------------------
------------------------------------------------------------
-------NIAMRQLL------------------------DNESFAADRSL----------
--------------------PKPANK------------TLKNVSALKRDLDAR-------
--AKNERYRAL-FRLTQDERLDGHT----------------DCTLWTPFAKMHVV--GQM
FVSNNYICFTSREEDL-CQLIIPLREVTIVEKADSSSVLPSPLSISTKNKMTFLFANLKD
RDFLVQR--ISDFLQRTPDGPCGVLQSENPS-----------------------------
-------------------------PSTPPSPPVL-----SLSESAQMQHYSPSLPT---
--ARKG----------------------LLQIYQQDGYWK-------------------G
------RVPR--QGWIYLSVNHLCFYSFLLGKEGYEMMLITA------------------
------------------------------------------
>gi|6330416|dbj|BAA86515.1|	Homo sapiens
-----------NSRAKKRPQLLRALARVPSPVRNRALGWSW-------------------
-------STASNSNRSTPACSPIL--RKR------SRSPTPQN-QDGDTMVEKGS-DHSS
--DKSPSTPEQGVQ-----------RSCSSQSGRSGGKNSK-------KSQSWYNVL---
---SPTYKQRNEDFRKLFK---QLPDTERLIVDYSCAL-QRDILLQGRLYLSENWICFYS
NIFRWETLLTVRLKDICSMTKEKTARL---IPNAIQVCTDSE-KHFFTSFGARDRTYMMM
FRLW-QNALLEKPLCPKELWHFVHQCYGNELGLTSDD-EDYVPPDDDFNTMGYCEEIPVE
ENEVNDSSSKSSIETKPDASPQLPKKSITNSTLT-STGSSEAPVSFDGLPLEEEALEG--
-DGSLEKELAIDNIM-----GEKIEMIAPVNSPS-LDFNDNEDIPTELSD-SSDTHDEG-
-EVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT-NSP-FQRDFMEQRRFSDII-FHPWKK
E-ENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDY
FYTINRYTLTRVARNK-SRLRVS---TELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLES
ELAKTESTYLAEMHRQSPKEKASKTTTVRRRKRPHA------------------------
-------------HLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPED------
--TPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYTTQTLTAWQ----G
LRLQE-RLPQSQTEWAQLLESQQKYHDTELQK--WREIIKSSVMLLDQMKDSLINLQNGI
RS--------------RDYTSESEEKR-----------NRYH
>gi|62122956|ref|NP_001014182.1	Rattus norvegicus
------------------------------------------------------------
-------------------------------------------------MVEKGS-DSSS
--------EKSGVSGT---------LSTQSLGSRNFIRNSK-------KMQSWYSML---
---CPTYKQRNEDFRKLFS---KLPEAERLIVDYSCAL-QREILLQGRLYLSENWICFYS
NIFRWETTISIQLKEVTCLKKEKTAKL---IPNAIQICTESE-KHFFTSFGARDRCFLLI
FRLW-QNALLEKTLSPRELWHLVHQCYGSELGLTSED-EDYVCPLQ-LNGLGSPKEV-GD
VIALSDISPSGAADRSQEPSPVGSRCGRVTPNLSRASGDADHGAEEDKEDQTDSQLDA--
-SSSQTVTPVAEPLS-----AEPAPPDGPTSNLGPLDLLSREELLTDTSNSSSSTGEEG-
-DLAALLPDLSGRLLINSVFHVGAERLQQMLFS-DSP-FLQGFLQQRKFTDVT-LSPWSS
D-SKCHQRRVLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDY
FYTAHRYCILGLARNK-ARLRVS---SEIRYRKQPWSLVKSLIEKSSWTGIEDYFHHLDR
ELAKAGKVSLE----EGGKDARGLLSGLRRRKRPLS------------------------
---------------WRGHRDGPQHPDPDPCTQ----TSMHTSGSLSSRFSEPS------
--VDQGPGAGIPSALVLISI-----VLIVLTALNALLFYRLWSLERTAHTFESWH----S
LALAKGKFPQTATEWAEILALQKHFHSVEVHK--WRQILRASVELLDEMKFSLEKLHQGI
TV--------------PDPPLDTQPHP----------DDSFP
>gi|112419240|gb|AAI21881.1|	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------QMFK---QL-----VSCPCCCPL----------------------
----------------------ALTQF---LPQILRQSHVEE------SQGEK-------
------------------------------------------------------------
------------------------------------------------------------
-AGGKSPQLGADRKP-----SLRATIGTPALA---LDLNGNENQNLDRSS-FSDTGDEE-
-DTKYPEEGIDGRLYINRVYQISAERMFQLLFT-QSH-FFVNFLGSRKVFDLE-CTPWQS
D-GNGKQTRTLTYTITINNPLVGKFTTATEKQVLYKGNQGGLSYSVEAEVLTHDVPYHDY
FYTVNKYSIVRTAQDK-CRLRVC---TDVRYKKQPWGLVKTFIERNSWSGLEDYFKQMES
DLMIEEN--------ASGSVLAEAGKSMRRRRRN--------------------------
-------------------------PNRSLGEHLPKHGAQHDPTHMGLDLRKDH------
--TGRKSAGGRNTTIILVMS----IFLVLLVLLNVTLFLKLSKIEHAAQSF---H----H
FHHKQERYASLHPGGIGGADQP---HKEKVFGPGLRGLLQDSISTIEQLKNSLLLLQKSF
DL--------------LNRTREEDPAGS--------------
>gi|28972662|dbj|BAC65747.1|	Mus musculus
----------------------QGCKGHSQWILVTVLMKGFKLS----------------
-------CTASNSNRSTPACSPIL--RKR------SRSPTPQN-QDGDTMVEKGS-DHSS
--DKSPSTPEQGVQ-----------RSCSSQSGRSGGKNSK-------KSQSWYNVL---
---SPTYKQRNEDFRKLFK---QLPDTERLIVDYSCAL-QRDILLQGRLYLSENWICFYS
NIFRWETLLTVRLKDICSMTKEKTARL---IPNAIQVCTDSE-KHFFTSFGARDRTYMMM
FRLW-QNALLEKPLCPKELWHFVHQCYGNELGLTSDD-EDYVPPDDDFNTMGYCEEIPIE
ENEVNDSSSKSSIETKPDASPQLPKKSITNSTLT-STGSSEAPVSFDGLPLEEEVMEG--
-DGSLEKELAIDNII-----GEKIEIMAPVTSPS-LDFNDNEDIPTELSD-SSDTHDEG-
-EVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT-NSP-FLRDFMEQRRFSDII-FHPWKK
E-ENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDY
FYTINRYTLTRVARNK-SRLRVS---TELRYRKQPWGFVKTFIEKNFWSGLEDYFRHLET
ELTKTESTYLAEIHRQSPKEKASKSSAVRRRKRPHA------------------------
-------------HLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPED------
--TPDGFHLQSVSKLLLVISCVICFSLVLLVVLNMMLFYKLWMLEYTTQTLTAWQ----G
LRLQE-RLPQSQTEWAQLLESQQKYHDTELQK--WREIIKSSVLLLDQMKDSLINLQNGI
RS--------------RDYTAESDEKR-----------NRYH
>gi|50293857|ref|XP_449340.1|	Candida glabrata
--------------------------------------MGLKKSNTSLY-----------
-------KADPAHPKLSEVNSVSS--SPARSLEELSVADSNEG-KDSLQVNDSSDLNPEN
K-SRSPTFFDSMVPAFLHRKTVVTTNGSTSNSGSDAATFSK----STFANGYHSSDLFAD
SKYHYASDKRDEAFHAIFR---SIPSTDRLIDDFGCLM-HKSHTYNGRIYISENHLSFNS
SFVDWMNKVTIPLVDIKHIEKTLSSSIGGTITQAITIEGADDSIYVLTGFISTDVTFDIL
MTVWSERNKIHQDNTNVVVPKIVHPEKVGAAEVNGLSASNLTSRRSSTSSSPLQKLIDGP
LFIDNSGTLKRSFQRLLTTPDNVGNLNNNDDIIN-KAILSIDETELVTDNVNESSGSSSD
TEGEGSADFVQDYKITKELRVHKLKPSCPIVYNGPLYFKKTE-FDYSPED--NDEH----
-------------VLKEITLDAPPGLVFEIIFSETEPSFHNQYLKELDSSSISEFGSFDK
I----ENERGFTYIKALNYSVGPKSTKCVVLEKLISKDYKNAINVV-VETKTPNVPSGNN
FSTKTRYMFRWNDATS-CSMKIS---YWVEWTGSSW--IKGMIESSCKTGQIEAADVIEK
LL----RTYLKENSIDEVVTLAEETETKEKQKLNGN------------------------
-------------------------DGGAPKDEKTTSTTKKT--EITVKKTPPT------
--------VKWFTWILIGLL----VTVIVLLLLNLTATFSLQKKI--------------D
KLLIH-SISSEALKSSHLLDVPAGRKNILESSNGFERELLLLLKDFARRRDDIQDLNPEM
IS--------------RIYSIIRNWNV---------------
>gi|50306669|ref|XP_453308.1|	Kluyveromyces lactis
MTDSDMEIPSRVNTTENDRRQSTSSSVFRTPLRRSRSGETSSLKSTPADPQLTETNGQST
SLRKYEECSDKRSTKEHLSNIMIQ--DQS------SFDSQAQS-QSNSFFKDMVS-TFSS
S-NNSVTEPEILAHRRENSGTITVSKLRPKSELPVGKPSLPLSELDLYDSKLYVNEFYAD
THYRFASDKRNNDFHQLFP---KVPASERLLDDFSSAL-NREFLIQGRVYITPMRVCFNS
NLLGWVTSLEIDIKDIVSLEKTSTAGL---FPNGICIHLPTE-KHYFASFISRDTTFKFL
EIIWHTRKELDYLTLRPDQLSLNRSHSLNDFLTGTNS---TCPPSRS-------------
SFAEADSAIESAIMSVDDSYPTNKSLSNLHEEDG-DSAGEDESGDEDDYEEEDDDAEGEK
LTSGDDYYYDEEAIA-SDYEEKSVRRVYKLKKKSKFHYDG----PYYFKA--------T-
-EFMYNPEENKETVLAELELNAPPGLVYQLMFSEECPDLILEFLKAQNSSQCSDIPPFDQ
VNPEGQHYRKYTYAKALNFPVGPKSTKCLVSEHILYCAYDNYINIVNT-TKTPDVPSGNS
FSVKTRYMYRWKDNTS-CVLKIS---YWVDWTGSSW--IKSMIDNSVNSGQVEATEKLLT
IVEEFV---------KNNVEESEMKVNIQPRKSLPQ------------------------
------------------------------SRRVSKISKKSSKLAVQQPSTPSN------
--LENKVHAALTKENII---------LSLLFIITLIMMFNTLC----------------Q
VRILR-KL--------------------------NKLMNTNSASVIEEIKDILNVY----
----------------NELPMSNEE-----------------
>gi|109109066|ref|XP_001108370.	Macaca mulatta
-------------------------------------MKGFKLS----------------
-------CTASNSNRSTPACSPIL--RKR------SRSPTPQN-QDGDTMVEKGS-DHSS
--DKSPSTPEQGVQ-----------RSCSSQSGRSGGKNSK-------RSQTWFYVL---
---SPTYKQRNEDFRKLFK---QLPDTERLIVDYSCAL-QRDILLQGRLYLSENWICFYS
NIFRWETLLTVRLKDICSMTKEKTARL---IPNAIQVCTDSE-KHFFTSFGARDRTYMMM
FRLW-QNALLEKPLCPKELWHFVHQCYGNELGLTSDD-EDYVPPDDDFNTMGYCEEIPVE
ENEVNDSSSKSSIETKPDASPQLPKKSITNSTLT-STGSSEAPVSFDGLPLEEEALEG--
-DGSLEKELAIDNIM-----GEKIEMIAPVNSPS-LDFNDNEDIPTELSD-SSDTHDEG-
-EVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT-NSP-FQRDFMEQRRFSDII-FHPWKK
E-ENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDY
FYTINRYTLTRVARNK-SRLRVS---TELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLES
ELAKTESTYLAEMHRQSPKEKASKTTTVRRRKRPHA------------------------
-------------HLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPED------
--TPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYTTQTLTAWQ----G
LRLQE-RLPQSQTEWAQLLESQQKYHDTELQK--WREIIKSSVMLLDQMKDSLINLQNGI
RS--------------RDYTSESEEKR-----------NRYH
>gi|147645287|sp|Q3KR56|GRM1A_R	Rattus norvegicus
------------------------------------------------------------
-----MFDTTPHSGRSSPSSSPSL--RKRLQLLPPSRPPSAPE-PEPGTMVEKGS-DSSS
--------EKSGVSGT---------LSTQSLGSRNFIRNSK-------KMQSWYSML---
---CPTYKQRNEDFRKLFS---KLPEAERLIVDYSCAL-QREILLQGRLYLSENWICFYS
NIFRWETTISIQLKEVTCLKKEKTAKL---IPNAIQICTESE-KHFFTSFGARDRCFLLI
FRLW-QNALLEKTLSPRELWHLVHQCYGSELGLTSED-EDYVCPLQ-LNGLGSPKEV-GD
VIALSDISPSGAADRSQEPSPVGSRCGRVTPNLSRASSDADHGAEEDKEDQTDSQLDA--
-SSSQTVTPVAEPLS-----AEPAPPDGPTSNLGPLDLLSREELLTDTSNSSSSTGEEG-
-DLAALLPDLSGRLLINSVFHVGAERLQQMLFS-DSP-FLQGFLQQRKFTDVT-LSPWSS
D-SKCHQRRVLTYTIPISNQLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDY
FYTAHRYCILGLARNK-ARLRVS---SEIRYRKQPWSLVKSLIEKSSWTGIEDYFHHLDR
ELAKAEKVSLE----EGGKDARGLLSGLRRRKRPLS------------------------
---------------WRGHRDGPQHPDPDPCTQ----TSMHTSGSLSSRFSEPS------
--VDQGPGAGIPSALVLISI-----VLIVLIALNALLFYRLWSLERTAHTFESWH----S
LALAKGKFPQTATEWAEILALQKHFHSVEVHK--WRQILRASVELLDEMKFSLEKLHQGI
TV--------------PDPPLDTQPHP----------DDSFP
>gi|73954617|ref|XP_859362.1|	Canis familiaris
-------------------------------------MKGFKLS----------------
-------CTASNSNRSTPACSPIL--RKR------SRSPTPQS-PDGDTMVEKGS-DHSS
--DKSPSTPEQGVQ-----------RSCSSQSGRSGGKNSKSHKRLSKKSQSWYNVL---
---SPTYKQRNEDFRKLFK---QLPDTERLIVDYSCAL-QRDILLQGRLYLSENWICFYS
NIFRWETLLTVRLKDICSMTKEKTARL---IPNAIQVCTDSE-KHFFTSFGARDRTYMMM
FRLW-QNALLEKPLCPKELWHFVHQCYGNELGLTSDD-EDYVPPDDDFNTMGYCEEIPVE
ENEVNDSSSKSSIETKPDASPQLPKKSITNSTLT-STGSSEAPVSFDGLPLEEEVLEG--
-DGSLEKELAIDNII-----GEKIEIVAPVTSPS-LDFNDNEDIPTELSD-SSDTHDEG-
-EVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT-DSP-FQRDFMEQRRFSDII-FHPWKK
E-ENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDY
FYTINRYTLTRVARNK-SRLRVS---TELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLES
ELTKTESTYLAEMHRQSPKEKTSKAPTVRRRKRPHA------------------------
-------------HLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPED------
--TPNGFHLQSVSKLLLIISCVICFSLVLLVILNMMLFYKLWMLEYTTQTLTAWQ----G
LRLQE-RLPQSQTEWAQLLESQQKYHDTELQK--WREIIKSSVMLLDQMKDSLINLQNGI
RS--------------RDYTSESEEKR-----------NRYH
>gi|6323101|ref|NP_013173.1|	Saccharomyces cerevisiae
MWGDSMRELGDAMDNELNAVKPVVEEGGMDGARKFIKGKSFQKSSTEHMLISPGRDG---
-------SVPLNGLKSSPA-DPHL--SDV------NSILDNHR-GGGETALTSVN-NIIM
--ATSTNGDSDGVDGDAKRPSI---SNCSSRSSFFDTVLSTFS--LKSNSQDTVTNEVKN
IEVQFASEEANKKFRQMFK---PLAPNTRLITDYFCYF-HREFPYQGRIYLSNTHLCFNS
TVLNWMAKLQIPLNEIKYLDKVTT------NSSAISVETVTN-RYTFSGFIARDEVFQLI
TRVWSKENLTNINDVLE-----VDERVSKKKGISS-------TPSSIFNNVSTNAYNDFI
STTTTEPTSRASYMSENDMLIEEAIRSVDDYMGT-PRASPSSSSSSSSS-----------
-SSSLGSSTTYYCRP-----VYRLKPNAPFQYEGPFHVQETMDFPYKPEA----------
---------NNEYVLLERQFSVPPGLLFIMMFNEDNPVFELSFLKTQDSSNISHIGTFEK
VNKDGQHYREFQYTKQLHFPVGPKSTNCEVAEILLHCDWERYINVLSI-TRTPNVPSGTS
FSTRTRYMFRWDDQGQGCILKIS---FWVDWNASSW--IKPMVESNCKNGQISATKDLVK
LVEEFVEKYV-----ELSKEKADTLKPLPSVTSFGS------------------------
-------------------PRKVAAPELTMVQPESKPEAEAEISEIGSDRWRFN------
----------WVNIIILV-----------LLVLNLLYLMKLNKKMDKLTNLMTHK----D
EVVAH----------ATLLDIPAKVQ--------WSRPRRGDVL----------------
------------------------------------------
>gi|126272949|ref|XP_001371326.	Monodelphis domestica
-------------------------MHSGFWAVPESTSESRQILRGGFMGQRGQE-----
-------FKKVNYGKWVALHTPLVTWRERETKPALCRWGVDVSFVSGSEMRTKCA-NNER
D-SLGPICFKQMHEKTVPLKIPVDQLEKLEEAPKERSPFLETLEESVHLPEGLKDEEIKK
SNLEVTPNKYNHQYHKLFK---DIPPEETVLKVCSCAL-QRDILIQGRLYISHNWLCFHA
SLFGKDIKVVIPVLSVQMIKKHKMARL---LPNGLAITTNTSRKYIFVSLISRDSVYDVL
RRV--------------------------------------------------CTHL---
------------------------------------------------------------
-QPSSKKSLSVR------------------------------EYPDEPDS----------
-------ESLEG------------------------------LIPEMK---------WRK
--------------------MSPPPLSLSLSDDVFPCIHRGSM-----------------
--------------------------SSLATKESSFSSEKPLASDNAIHTEEEL------
---------------EGEPE----------------------------------------
-------------------------------------------GSPELRPWDYQ------
-----------LLKVFFVLI-------CLLVVSSSYMAFRIFRLEQQLCSLN-WD----S
VSYRH-RPNSGTIGSPGYYLQHPH----------YTGLPQCPIQEQDGLGGLLMNTVNM-
------------------------------------------
>gi|118083518|ref|XP_416574.2|	Gallus gallus
------------------------MPKMLREQWEDDLFVRFLIA----------------
-------LTSFNQKFGHTEYSDIQ--KEI------SLWLNSFI-AEEVDEVDHGV-----
--TSQLVADSQETH-----------SSCTEKMQVPA---------QYSWSADWSFWL---
--SSSTYKYRSEEFKRQFS---HLPDSERLIVDYACAL-QKDILLQGRLYLSENWLCFHS
NIFRWETTISIALKDITFMTKEKTARL---IPNAIQIATKGE-KFFFTSFSARDRSYLSI
FRLW-QNVLLDKRLTKQEFWQLVHQSYGSELGLNTEEMESFHSSSED---NGQCRSSVCD
EPGERDDKLPKTVGLVRESTLQTEGESLNRHALS-GVE----------------------
-ESLSEKQIKKSPLP--SSERKSVKLVRSRSLEKSLDLNENENLQEKSSA--SDSEEAV-
-KETASENDVYGRLFINRVFHITADKMFEILFT-NSH-FMQRFLNSRSIVDAV-STPWNR
D-SSGNQLRTLTYTVTINNPLCGKFTTATEKQILHKQSQKGQSYQVDAEVLTHDVPYHDY
FYTVNRYYISRTSSHK-CRLRVS---AEVKYKKQPWGLVKSVIEKNTWGGIQENFKQLES
ELLMEEYAI------NQSIEDSGKLVALRRRRRTLH------------------------
---------------------------RSLAESLPKRSSQHSSGDMGLESQGSI--I---
--GRKRDAISRTTAIIVVMS----VFLLLLVLLNVTLFLKLSKIEHAAQSLY-------H
VQLQEESSLNISPEMGSKEEIPQ-YDKEQVKH--VKGVLRDSIEMLEQLKLSLSMLQRSF
DH--------------LNKTQSSKTES---------------
>gi|67969800|dbj|BAE01248.1|	Macaca fascicularis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------MTKEKTARL---IPNAIQVCTDSE-KHFFTSFGARDRTYMMM
FRLW-QNALLEKPLCPKELWHFVHQCYGNELGLTSDD-EDYVPPDDDFNTMGYCEEIPVE
ENEVNDSSSKSSIETKPDASPQLPKKSITNSTLT-STGSSEAPVSFDGLPLEEEALEG--
-DGSLEKELAIDNIM-----GEKIEMIAPVNSPS-LDFNDNEDIPTELSD-SSDTHDEG-
-EVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT-NSP-FQRDFMEQRRFSDII-FHPWKK
E-ENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDY
FYTINRYTLTRVARNK-SRLRVS---TELRYRKQPWGLVKTFIEKNFWGGLEDYFRHLES
ELAKTESTYLAEMHRQSPKEKASKTTTVRRRKRPHA------------------------
-------------HLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPED------
--TPNGFHLQSVSKLLLVISCV----LVLLVILNMMLFYKLWMLEYTTQTLTAWQ----G
LRLQE-RLPQSQTEWAQLLESQQKYHDTELQK--WREIIKSSVMLLDQMKDSLINLQNGI
RS--------------RDYTSESEEKR-----------NRYH
>gi|47208073|emb|CAF93589.1|	Tetraodon nigroviridis
------------------------------------------------------------
------FSTASNSPRSTPGSSPSL--RRR------VLGGSRANETEVGGEKSSGG-GGGC
SDSPLPSIASASSL-----------SSAYPLAARHFTRNAK-------KMQSWYNVL---
---SPTYKQRNEEFRRLFK---KLPDTERLIVDYSCAL-QKDILLQGRIYLSENWLCFYS
NIFRWETTITILLKDVTSMTKEKTAKL---IPNAIQISTDNE-KYL--------------
--------------------------------------EE--------------------
------------------------------------------------------------
-GGDSLSESANQTMP---------PPTTSLGNLSALDITNDEDLPTDPSN-SSDTQEESA
CEVESFCSDLSGRLHINTVVRMSVDKLHDLLFSGDTH-FIQHLFSQRHFTDLS-VGEWQQ
DSSSGNRNRVLSYTIALNNPLGPKTATVVETQTLHKSSARGECYVVDSEVITSGIPYQDY
FFTVHRYCLTSINKHK-SRLRVS---SDICYRKQPWSLVKALIEKNTWSGIEEYYRHMES
ELLQNE---VVGTTGEAVEGESKTPPSLRRRKRTCS------------------------
-----------------------RRQGDKEKEREVGGMGSGDRADRGVREHRDR------
------REAVWAVDLTLDLSFLYVSSLVVLVALNMLLFYKLYALERAAHTLETWH----S
FSLADSPLPQTAGEWAQVLQLQRQFHQAQLSK--WQQILQSSVTLLDQVG----------
------------------------------------------
>gi|114588526|ref|XP_516656.2|	Pan troglodytes
-------------------MFMYECEDASEPMLRYSSKTSLQANPETPIVRNPSRPPEGA
RSCGWKYSEGRRRRRAESVTRSAR--WRW------ARGVAVRCARGGAAAAEGAAMEGAP
NVRQVMNEGDSSLATELQEDVEENPSPTVEENNVVVKKQGPN---LHNWSGDWSFWI---
--SSSTYKDRNEEYRRQFT---HLPDTERLIADYACAL-QRDILLQGRLYLSENWLCFYS
NIFRWETTISIALKNITFMTKEKTARL---IPNAIQIVTESE-KFFFTSFGARDRSYLSI
FRLW-QNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEDVQPRS-PGRSSLD
DSGERDEKLSKSISFTSESISRVS-----------ETESFDGNSSKGGLGKE--------
-ESQNEKQTKKSLLP-------TLEKKLTRVPSKSLDLNKNEYLSLDKSS-TSDSVDE--
--ENVPEKDLHGRLFINRIFHISADRMFELLFT-SSR-FMQKFASSRNIIDVV-STPWTA
E-LGGDQLRTMTYTVVLNSPLTGKCTAATEKQTLYKESREARFYLVDSEVLTHDVPYHDY
FYTVNRYCIIRSSKQK-CRLRVS---TDLKYRKQPWGLVKSLIEKNSWSSLEDYFKQLES
DLLIEESVL------NQAIEDPGKLSGLRRRRRTFN------------------------
----------------------------RTAETVPKLSSQHSSGDVGLGAKGDI------
--TGKKKEMENYNVTLIVVM---SIFVLLLVLLNVTLFLKLSKIEHAAQSFY-------R
LRLQEEKSLNLASDMVSRAETIQKNKDQAHR---LKGVLRDSIVMLEQLKSSLIMLQKTF
DLLN------------KNKTGMAVES----------------
>gi|149635297|ref|XP_001510727.	Ornithorhynchus anatinus
------------------------------------------------------------
----------------------------------------------MDSLTESGV-LLSL
LLQQDSKSLLCSLQ-----------RFNSTLPGQDTWKNLG--------SEEIPAVL---
---SPTYKQRNEDFRKLFK---QLPDTERLIVDYSCAL-QRDILLQGRLYLSENWICFYS
NIFRWETLLTVRLKDICSMTKEKTARL---IPNAIQVCTDTE-KHFFTSFGARDRTYMMM
FRLW-QNALLDKPLCPKELWHFVHQCYGNELGLTSDD-EDYVPPDDDFNTMGYCEEIPVE
ENEVNDSSSKSSVEAKADASPQIPKKSITNSTLT-STGSSEAPISFDGLPLEEEVLEE--
-DGPLEPELSLANII-----EEKIEMIAPVNSPS-LDFNDNEDIPTELSD-SSDTHDEG-
-EVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT-DSP-FQRDFMEQRRFSDII-FHPWKK
E-ESGNQSRVILYTITLTNPLAPKTATVTETQTMYKASQESECYVIDAEVLTHDVPYHDY
FYTINRYTLTRVARNK-SRLRIS---TELRYRKQPWGLVKTFIEKNFWSGLEEYFRHLES
ELTKTESTYLAEVHRQSPKEKAGKVSALRRRKRPHP------------------------
-------------HLRVPHLEEVMSPVTTPTDEEVGRRTKHVAGSTQTRLIPEE------
--NSEGIHLQSVSKLLLIISCVICFSLVLLVILNMLLFYKLWMLEYTTQTLTVWQ----G
LRFQE-RLPQSQTEWAQLLDSQQKYHDTELQK--WKEIIKSSVMLLDQMKDSLVNLQSSI
RS--------------RDYVSESEEKR-----------HRFH
>gi|157017974|gb|EAA07690.4|	Anopheles gambiae
----------------------------MAGKPPSSSRPGQPKSA---------------
-------NSVGLGTRPLPLSSTI---EPL------SSVDTPGGQPEGAAHLNVLS-RSPS
--HSTTKSDPKSLKSLSPSARSSTVRSSSPHPLKSFSSTRDAGVDKPDKPEKHHKKK---
---EGGLSWEQKKFAQHFA---QVPDDEVVLDYFSCAL-VGDILLQGYLYITQNYFAFYS
NVFGYVTKLLIPTVSVLDISREKTAYM---FPNAVGVKTRDD-RHVFGSFLSREAAYYLM
CSVW----------------------------------ERATTPHSDS------------
------------------------------------------------------------
-LGSIQHT-----------------RLAPL-----LHAEGSEGSLDEDSS----------
-----CYDGN------------------------ESS-----FHGKDDLPDLL-------
--DSGD-----SHEKQLNATEGGGTNQSSDDSTVLLKQKK-----LKKELLLK-------
-----------------SPAIV----------KSP-AILKVAVAAGALDGLKAGDKAL--
------------------------------------------------------------
-------------------------PLLLAGDGTMGSSIGASGAGGKLRHI---------
--LPSDFGIIHIGLILA----------VLLALFSCFLAYKIYALQA-------------R
LAAPPIRLGDDTDFYLDVLRWQKRLHSKSKEE--AQIVLSSNLEQIIKVRKSLETLSLLI
QDSGTD----------GSGSGGREDTPGAALLSAMIAGESGR
>gi|149716613|ref|XP_001503471.	Equus caballus
-------------------------------------MKGFKLS----------------
-------CTASNSNRSTPACSPIL--RKR------SRSPTPQN-PDGDTMVEKGS-DHSS
--DKSPSTPEQGVQ-----------RSCSSQSGRSGGKNSKSHKRLSKKSQSWYNVL---
---SPTYKQRNEDFRKLFK---QLPDTERLIVDYSCAL-QRDILLQGRLYLSENWICFYS
NIFRWETLLTVRLKDICSMTKEKTARL---IPNAIQVCTDSE-KHFFTSFGARDRTYMMM
FRLW-QNALLEKPLCPKELWHFVHQCYGNELGLTSDD-EDYVPPDDDFNTMGYCEEIPVE
ENEVNDSSSKSSIETKPDASPQLPKKSITNSTLT-STGSSEAPVSFDGLPLEEEVLEG--
-DGSLEKELAIDSII-----GEKIEIIAPVNSPS-LDFNDNEDIPTELSD-SSDTHDEG-
-EVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT-DSP-FQRDFMEQRRFSDII-FHPWKK
E-ENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDY
FYTINRYTLTRVARNK-SRLRVS---TELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLES
ELTKTESTYLAEMHRQSPKEKASKPTTVRRRKRPHA------------------------
-------------HLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPED------
--TPNGFHLQSVSKLLLVISCVICFSLVLLVILNMMLFYKLWMLEYTTQTLTAWQ----G
LRLQE-RLPQSQTEWAQLLESQQKYHDTELQK--WREIIKSSVMLLDQMKDSLINLQNGI
RS--------------RDYTSESEEKR-----------NRYH
>gi|21428794|gb|AAM50116.1|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MEMKRKLG---KMHR-------------QRE------------------
-------------------EGKNAAES---VPTDVSDSSDSE------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------ENNLPFVPTT----------
----ECTSTHEGRQIVHTILPINVDTLFNLLFS-KSK-FITDFHAMRKSTDLV-LGEWTK
N-EEGLQVRTVNVTVQLAASVGPKTSKVTEYQTQRECSKPGELYSIDVNSVNAGIPYAES
FSVLIHFCLARTVDDH-TMLSIH---TQIKYKKSIWGVVKGFIEKNTWAGLEDFFGAQLH
ALQSE--TCIPPAKGKGRRPRRGTATQIRPLEEAVGPAPAVDPLETQMLAAGGIPGAAVG
AAAGHPLLLEGGKQQQLHHQQQMHHHHLQPHKQHLQQQQLHLGGGDGQPLASGQ------
--GSQGHRLRHKGLWLLVIL-----LLCLMLALNVILLLKLWRLEERIDVDLNRRARMPS
LAALS-ELPSTNQEWLELLRDQEMAHENELHK--WQQVLQTAIELLKKVSIVCEKITNDS
HL--------------RQSIESMSMAG-----------RTEF
>gi|119907181|ref|XP_001249968.	Bos taurus
-------------------------------------MKGFKLS----------------
-------CTASNSNRSTPACSPIL--RKR------SRSPTPQN-VDGDTMVEKGS-DHSS
--DKSPSTPEQGVQ-----------RSCSSQSGRSGGKNSKSHKRLSKKSQSWYNVL---
---SPTYKQRNEDFRKLFK---QLPDTERLIVDYSCAL-QRDILLQGRLYLSENWICFYS
NIFRWETLLTVRLKDICSMTKEKTARL---IPNAIQVCTDSE-KHFFTSFGARDRTYMMM
FRLW-QNALLEKPLCPKELWHFVHQCYGNELGLTSDD-EDYVPPDDDFNTMGYCEEIPVE
ENEVNDSSSKSSIETKPDASPQLPKKSITNSTLT-STGSSEAPVSFDGLPLEEEVLEG--
-DGSLEKELAIDNII-----GEKIEIIAPVNSPS-LDFNDNEDIPTELSD-SSDTHDEG-
-EVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT-DSP-FQRDFMEQRRFSDII-FHPWKK
E-ENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDY
FYTINRYTLTRVARNK-SRLRVS---TELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLES
ELTKTESTYLAEMHRQSPKEKASKPPTVRRRKRPHA------------------------
-------------HLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPED------
--GPSGFHLQSVSKLLLVISCVICFSLVLLVILNVMLFYKLWMLEYTTQTLTAWQ----G
LRLQE-RLPQSQTEWAQLLESQQKYHDTELQK--WREIIKSSVMLLDQMKDSLINLQNGI
RS--------------RDYTSESEEKR-----------NRYH
