>gi|19920906|ref|NP_609177.1|	Drosophila melanogaster
------------------MGTNSGATAGINNKPVG--GATGAGVLVGGGVGGANSSI---
---------------------------GGVLSNSLGGGGSGGLSISG----LNAGGQNAN
VGG----M--GNVGG-------DDGGNGMVGGGVNNQQA--TTPQY----------TIP-
----------------GILHFIQHEWSRFELERSQWDVDRAELQ----------------
---------------------ARIAMLLGERKCLESLKSDLTRRIKMLEYALRQERAKFY
RLKYGTDPP-----------------QLNEFKPSNEDAGLAGEVATD------SEVPYSS
VSNTT----------WR-------------QGRQMLRQYLA---EIGYTDNIIDVRSNRV
RSILGLNNNAEHD-------GSGGGLGGGLGGGTGG--ENLSPNI---------------
----------------------------NGN-------ESNKRASETEGRHTPAKK-VQ-
---QSIDEIIV-------DTEA-----AVMAN------FEF-LGATEMS-----------
----------DDDEISDDLEMVATDNDDTDVKLA--KRAKSGKDML--------------
------------------------------------------------------------
------------------------------------------------------------
---------TEEVDGSLGLGELAQLTVNNESD-GAYD-ANSKDGTGGSAGGAGYRKTWNA
KYTLRSHFDGVRSLIF----HPEE---PVLITASEDHTLKLWNLQK--------------
-TVQ--AKKSASL-DVEP------LYTFRAHTGPVLCLGMSSSGET------------CY
SGGLDGNIECWQLP-SPNIDPYDCY---------------------------DPNVHSG-
-TLEGHTDAVWGL-------------------TTMQSN---IVSCSADGTVKLW------
---------------------------------SPYNKEPLLRTYTASEAEGV-------
--PSSVDFVRNEVDHIVVAYNSAHCIVYDTETGKQVVRLEAAQEMSGNTGK---FINKVV
S-----------------------------------HPTLPITITAHEDRHIRFWDNTSG
--TLVHSMVAHLEPVTSLAVDA-HGLYLLSGSHDCSIRLWNLDNKTCVQEITAHRKKFDE
--SIFDVAFHAT---KPYIASAGADGLAKVFV----------------------------
------------------------------------------------
>gi|110765310|ref|XP_623216.2|	Apis mellifera
----------------------------------------MKVPSQFCGSTME-------
--------------------------ENSSSASQNHNGQ------------LSSGANVPL
TNN-------KHQGN----------DNGTNGDAKN------ERPQY----------SMP-
----------------GILHFIQHEWTRFELERSQWELDKAEFQ----------------
---------------------ARIAFLQGERKGQERLKNDLVRRIKMLEYALKQERARYH
KLKYGTDLV-----------------IQGDTKPPIYEEGICNCPNSDVGGGGDGEAPFTS
VSNIS----------WR-------------QGRQILRQYLQ---EIGYTDTIIDVRSSRV
RSLLGLSNNTDSE----------DMNTPALNGNEPS--NKQAS-----------------
----------------------------DNS-------DTGLLNSVRRTSEKKVEQ-RS-
---SIAEAIIL-------DTEA-----AVMAN------FEF-LANTDMDM----------
----------EEEEGDVEDDTYDTNMD---------PKPNKPPMLLTEDVDAEAEEVLNE
LNLLTEIEESPPG--------------------------------SIRYLSEW-------
--NAIHRGAHTDP-----------------------------------------K-----
-------RLNEEGDSTLELGELEQLCVNNEAE-TSYDVTTTKE---------SLRKTWNA
KYTLRSHFDAVRALVF----HPTD---PVLITASDDHTLKLWNLHK--------------
-TLP--AKKSASL-DVEP------LYTFRSHTGPVLCLAMCSTGSQ------------CY
SGGLDGMIHCWTLP-SANIDPYDSY---------------------------EPSVLSQ-
-TLKGHTNAVWGLSM-----------------YQLRSQ---LLSISADGTVKLW------
---------------------------------SPQSKSPLLHTYVSEQD-GI-------
--PSSVDFIRDESNKLVVAYDRA-CVVFDTETGESVARLE------ANETK---GVNRVV
A-----------------------------------HPTLPLVVAAHEDRHIRFYDHRSA
--TLAHAMVAHLDAVTSLAVDP-HGLYLLSGSHDCSIRLWNMDNKTCVQEITAHRKKFDE
--SILDVAFHPS---RPFIASAGADALAKVYV----------------------------
------------------------------------------------
>gi|70985316|ref|XP_748164.1|	Aspergillus fumigatus
------------------------------------------------------------
------------------------------------------------------------
-MA-------GGGGY------VGPGGDGSSNGGQP------HGTEY----------TLQ-
----------------GVMRFLQTEWHRHERDRNAWEIERAEMR----------------
---------------------SRIGRLEGDVRTSKRLHESLGKHVRLLEAALKKEREKVK
KLSNNEPIE----DMRDSKEIARESINALKSQRSKSQADLTTDIDTD------HQLGVRQ
ENERE-------------------------KSRLYLSKCSQ---EVAFH-VIPTSHPAPD
LNDLELSNHMYAN---------HNMPQQSIEEAYI-------------------------
--------------------------------------QQQRQKQQQQQQQANHMM-ARE
VALQNHQPIVT-------HYSDNSNVSRAPNQ------FLP-TVARDIMDKSPLEAQQTH
ATAI------DNRRQAFESGLSDERAGAAKQQYD--NTQAAAKEETQSQQEDQIQD--TD
GWNFDENPAQESR--------------------------------TAHIPP------HRP
DMDAFPNANFAGP-----------------------------------------K-----
--------SPSRGGSVSHRRKSSGSKRKTEGATDVGAGAIQKQ-----------DPIFKV
RFALRGHLDVIRSVIFTGGGSPSE---PEICTCSDDGTIKRWIIPA---------SYGAY
GSHG--GSSGNDL-DITS------YFTHRGHVGAVTALAACSPSQNFSNGGRALGDGWVF
SGGQDASVRVWE---RGRVDP------------------------------------KA-
-TLDGHTDAVWGLCVLPGTAGTVFGDSSSHYGGPDRIL---LASGAADGRILIWAVSAPP
QVSSPQAGSRR----AGGSRRANSISSGSNFPSSPQPSTATTTPFHYTLVHHILRAD--S
PSPTCISPLSLAGVNFVVSYTDASILVYDTRTGEEIVGMASLETYDGTPST---GVNSVV
ATTIGFDGSAGLDPSRTLADEEVVHGATGS------SAVEGVIISGYEDRYIRFFDANSG
--------------------------------HDASLRFWNLEKRSCTQEITSHRLMRGE
--GVCAVTWSRD---GRWVVSGGGDGVVKVFSR---------------------------
------------------------------------------------
>gi|147903829|ref|NP_001087621.	Xenopus laevis
-----------------------------------------MDEQAGPGVFFNNNNN---
-----------------------------SLLSAGTGPAGAGKG-------FEAGAADAA
SVS-------GGGGG------------GSAGTA--------ARAQY----------SIP-
----------------GILHFLQHEWARFEVERAHWEVERAEMQ----------------
---------------------AQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDMKPPNYDSDEANENEIQ---------PPQQ
NSQFI----------WK-------------QSRQLLRQYLQ---EVGYTDTILDVKSKRV
RSLLGLSADSSDR-------LTDTKQDSMVNGTETE--LPNPLVLGKPDMTDS-------
--------ASVLETFKFLENAAAEF-------------SDEEDEEENESRDKTIID-SAT
---IVRRRIIP-------DSND--DTEEALKE------FDF-LGS-DDGEG-GESRSAGD
GTEW------EKEDQSPITESWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LREVDELPSLQPS--------------------------------VVSSSRPAS---SRI
SEQEMNRADEVEA-----------------------------------------LTFPPS
SGKSFIMGADEALENELGLGELAGLTVANEADSLTYDIGNNKD---------ALRKTWNP
KFTLRSHFDGIRGLAF----HPSE---PVLITASEDHTLKMWNLQK--------------
-TAP--AKKSASL-DIEP------IYTFRAHMGPVLCVVTSSNGEQ------------CY
SGGTDGVIQSWNTP-NSNVDPYDSY---------------------------DPTVLRG-
-AYEGHTDAVWGLVY-----------------SAVHQR---LLSAAADGTIRIW------
---------------------------------NAAEVSPALSIFNENQELGI-------
--PSSVDLVSCDPAHLVASFNNGHTNIFNMETHQKVLTLESSIDTAVNSTC---QINRVI
S-----------------------------------HPTLPISITAHEDRHIKFYDNNTG
--KLIHSMVAHLDAVTSLAVDP-NGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKSDE
--SIYDVAFHPS---KCYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|58258149|ref|XP_566487.1|	Cryptococcus neoformans
-----------------------------------MNRAVQRSQLFNPAGQQTRSQYDP-
--------------------------QNPGVQHRGPAGPAPQQQYQQYQQYQQPQQQGQP
QQQ-------QQQQQQQLSQQGPQSTNGTADGASGSGST--PGQEM----------NLA-
----------------SVLHYLQSEWRRWERDRNEWEIERAEMR----------------
---------------------ARIALLEGQRRSAENLKVDLLRRVKMLEFALRQERTK--
RVGAGGKLN-SVPPTRLAALQDEDRLSTGDKEGSGSEGSQEDILEKPTKVNGVHSAAVGK
SSTIMSRSQPAEANQWKSIGVAPRDPKARARSREYLKQCLQ---EISYLTSPGALNPLPP
YPPVDPSALPQPD-------VSHDPNHPEVDLYERPRKELSEEPV---------------
---------PPLHTRKRNDEAAETKETAGST-------SASEDDQVNGEKDKPIPS----
---IPTPALPP-------GSSSSFPTSQPMEKSVSPSPLAF-HRPGLDPALLPPSDN---
----------SGPPSSPSPRTVSLPDISATKSEDEPRSPGAGKDSDEPGKQL--------
---------LTAI--------------------------------YRPDSKTAWREELKA
ANEEAEKAKEERA-----------------------------------------R-----
-------KVPDQAEDD----RLTTLSLNTEEEEIKAD-----D---------SVDKIWVS
KRSLKSHLDIVRAIAFA---HGPG---IMLATGGDDCTVKVWSVDSASI-----ISHRYV
LSAPEISGRHTAQ-EIEP------IMTLRGHTAAITSVAISNALSI------------IF
SASLDSTIRLWQLP-AHNHDPYATY---------------------------NPSVAVQ-
-TLEGHTESVWDICLLPPQEVSPAGK------EGIEGR---LVSASSDGSVKLW------
---------------------------------ERSGSSPSASNWKLEKSFSSFGEG---
VIPTCLAVFNLDFGKVLVGTSDGKARLWDVDAGEEV-RLFGEEGQGVDS-----QVNAIL
S-----------------------------------HPTLPAIVTAHEDGYLRFYDAKSS
STTPTHTVLAHPAPITSLALSPSSPTCILTSSVDCTVRLWDLTKKTSIQELAGHRGRADE
--GVCAVASHPE---LPVIGSAGADGVVRLWGLA--------------------------
------------------------------------------------
>gi|114576940|ref|XP_525732.2|	Pan troglodytes
-----------------------------------------MDEQAGPGVFFS-------
---------------------------------NNHPGAGGAKG-------LGPLAEAAA
AGD-------G----------------AAAAGA--------ARAQY----------SLP-
----------------GILHFLQHEWARFEVERAQWEVERAELQ----------------
---------------------AQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDMKPPSYDSDEGNETEVQ----------PQQ
NSQLM----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVKSKRV
RALLGFSSDVTDR-------EDDKNQDSVVNGTEAE--VKETAMIGKSELTDS-------
--------ASVLDNFKFLESAAADF-------------SDEDEDDDVDGREKSVID-TST
---IVRKKALP-------DSGEDRDTKEALKE------FDF-LVTSEEGDN--ESRSAGD
GTDW------EKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LRDVDELPSLQPS--------------------------------VGSPSRPSS---SRL
PEHEINRADEVEA-----------------------------------------LTFPPS
SGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKD---------ALRKTWNP
KFTLRSHFDGIRALAF----HPIE---PVLITASEDHTLKMWNLQK--------------
-TAP--AKKSTSL-DVEP------IYTFRAHKGPVLCVVMSSNGEQ------------CY
SGGTDGLIQGWNTT-NPNIDPYDSY---------------------------DPSVLRG-
-PLLGHTDAVWGLAY-----------------SAAHQR---LLSCSADGTLRLW------
---------------------------------NTTEVAPALSVFNDTKELGI-------
--PASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTTANSSC---QINRVI
S-----------------------------------HPTLPISITAHEDRHIKFYDNNTG
--KLIHSMVAHLEAVTSLAVDP-NGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEE
--SIHDVAFHPS---KCYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|125985659|ref|XP_001356593.	Drosophila pseudoobscura
------------------MGTNSGATAGINNKPVG-----GAGAGVLGGVGGANSSI---
---------------------------GGVLSNSLGGGGGLS--ISG----LNSGGQNAN
VGGLVTGMGSGNNMN-------DDGGNGMSGGPNNQQA---TTPQY----------TIP-
----------------GILHFIQHEWSRFELERSQWDVDRAELQ----------------
---------------------ARIAMLLGERKCLESLKSDLTRRIKMLEYALRQERAKFY
RLKYGTDPP-----------------QLNEFKPTNEDSGLTGDVATD------SEVPYSS
VSNTT----------WR-------------QGRQMLRQYLA---EIGYTDNIIDVRSNRV
RSILGLNNNAEHD-------GSGGGL------GTGG--ENISPNI---------------
----------------------------NGN-------ESNKRASDTEGRHTPAKKQVQ-
---QASDGIII-------DTEA-----AVMAN------FEF-LGPTEMS-----------
----------DDDEISDDLEMVATDSDDTDVKLA--KRAKSGKDML--------------
------------------------------------------------------------
------------------------------------------------------------
---------TEEVDGSLGLGELAQLTVNNESD-GAYD-SNAKDGTGGSAGGAGYRKTWNA
KYTLRSHFDGVRSLIF----HPEE---PVLITASEDHTLKLWNLQK--------------
-TVQ--AKKSASL-DVEP------LYTFRAHTGPVLCLGMSTSGET------------CY
SGGLDGNIECWQLP-SPNIDPYDCY---------------------------DPNVHSS-
-TLEGHTDAVWGL-------------------TTMQNN---IVSCSADGTVKLW------
---------------------------------SPYNKDPMLRTYTAAEAEGV-------
--PSSVDFVRNEVDHIVVAYNSAHCIIYDTETGKQVIKLEAAQEMSGNTGK---FINKVV
S-----------------------------------HPTLPVTITAHEDRHIRFWDNTSG
--TLVHSMVAHLEPVTSLAVDA-HGLYLLSGSHDCSIRLWNLDNKTCVQEITAHRKKFDE
--SIFDVAFHAT---KPYIASAGADGLAKVFV----------------------------
------------------------------------------------
>gi|73947242|ref|XP_865297.1|	Canis familiaris
----------------------------------------MMEERAAAAVAAAASSCRPL
G------------------------------SGAGPGPTGAAPA-------SAPAPGPGP
AGK-------GGGGG---------GSPGPTAGPEPL--------------------SLP-
----------------GILHFIQHEWARFEAEKARWEAERAELQ----------------
---------------------AQVAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYH
KLKFGTDLN------------------QGEKKPELAEQVSNGPVESV----------TLE
NSPLV----------WK-------------EGRQLLRQYLE---EVGYTDTILDMRSKRV
RSLLGRSLELNGAVEPSEGGPRATPGPGGLSGGESLLVKQIEEQIKRNAAGKDGKERLS-
--------GSVLEQIPFLQNCEDED---SDE-------DDDLDSV---QHKKQRVK----
---LPSKALVP----EMEDEDEEDDSEDAINE------FDF-LGSGEEGEGSPDPR----
------------------------------------RCTGEGTHHELESRRVKLQGILAD
LRDVDGLP--PKV--------------------------------TGPPPGTPQ---PRP
HEGSFGFSSDVFI-----------------------------------------M-----
---------DTIGGGEVSLGDLADLTVTNDND-LSCDLSDSKD---------AFKKTWNP
KFTLRSHYDGVRSLAF----HHSQ---SALLTASEDGTLKLWNLQK--------------
-AVT--AKKNAAL-DVEP------IHAFRAHRGPVLAVAMGSNSEC------------CY
SGGADARIHSWKIP-DLNMDPYDGY---------------------------DPSVLSH-
-VLEGHGDAVWGLAF-----------------SSASQR---LASCSADGTIRIW------
---------------------------------DPSSSPACLCTFLTASDHGI-------
--PTSVAFTSTEPAHIVASFRSGDTVLYDLEAGSALLSLESRGSSGKRGPQGRGLINQVV
S-----------------------------------HPNQPLTITAHDDRGIRFLDSRTG
--KSVHSMVAHLDAVTCLAVDP-NGVFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEE
--AIHAVACHPS---KALIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|121719336|ref|XP_001276367.	Aspergillus clavatus
------------------------------------------------------------
----------------------------------------------------------MA
GGG-------GYVGP---------GGDGSSNGGQP------QGTEY----------TLQ-
----------------GVMRFLQTEWHRHERDRNAWEIERAEMR----------------
---------------------SRIGRLEGDARTSKRLHESLGKHVRLLEAALKKEREKVK
KLSNNEPIE-DKRDPKEIARESINALKAQRSQSHIESPPVENDSDNQ--------PGVRQ
ENERD-------------------------KSRLYLSKCSQ---EVAFH-IIPSSHPPPD
LNDMEMSNHVYAN----HSMSQQSLEEAYMQQQRQK--QQQQQQQQQQQQQQQQQ-----
----------------------------QQQ-------QQQQQHQQQQQQQANHMM-ARE
VALQNHQPALT-------HYSDNSNLSRGNQ-------FLP-LGSRDVLEKRPLEPQQTS
VTAL------DSRKQGFDHIITDERVGSTRQQFE--NAPAAGKEEI-KAQHSEDQSQDTD
GWNFDDTPAPEPR--------------------------------ADHIPP------HRP
DVDVFPNANFSGS-----------------------------------------K-----
--------SPSRGGSLSHRRKSSGSKRKSEGVIDSGAGAGQKQ-----------DSIFKV
RFALRGHLDVIRSVIFTGGGSPSE---PEICTCSDDGTIKRWIIPA---------SYGAY
GSHG--AGSSNDL-DITS------YFTHRGHVGAVTALAACSPSQNFSNGGRALGDGWVF
SGGQDASVRVWE---RGRIDP------------------------------------KA-
-TLDGHTDAVWGLCVLPGTVGSVFGDSSSRYGGPDRIL---LASGAADGRILIWAVSAPP
QLSSPQAGSRR----AGGSRRANSISSGSNFPSSPQPSTATTTPFHYTLVHHILRNA--S
PSPTCISPLSLAGVNFVVSYTDASILVYDTRTGEEIVGMASLETYDGTPST---GVNSVV
ATTVGFDGSAGLDPSRTMAEEEVVHGATGS------SAVEGVIISGYEDRYIRLFDANSG
--QCTYTMLAHPAAIAALSLSP-NGRELISAGHDASLRFWDLEKRSCTQEITSHRLMRGE
--GVCAVTWSRD---GRWVVSGGGDGVVKVFSR---------------------------
------------------------------------------------
>gi|126282002|ref|XP_001364248.	Monodelphis domestica
-----------------------------------------MDELPGGGGGGGP------
---------------------------GMAGPPRQQQGPGVNMN-------LQPGAGGGA
AAG-------GGQST-------AVEGAGPSTGPELS-----RPQQY----------TIP-
----------------GILHYIQHEWARFEMERAHWEVERAELQ----------------
---------------------ARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDLKMPTFESEETKDTEAP---------TIPQ
NSQLT----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVRSQRV
RSLLGLSGSEPNG------SVETKNLEQILNGGDSP-SKQKGQDIKRSS-----------
--------GDVLETFNFLENADDSD---EEE-------ESDMIEDLTDGKEKHRMN-KHK
---IGNEGLAA-------DLTDDPDTEEALKE------FDF-LVTAEDGEGAGEARSSGD
GTEW------DKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKRVNRTKLHDMIAD
LGD-DELPHIPSG--------------------------------IINQSRSPS---TRM
TDHEGARAEEAEP-----------------------------------------ITFPSG
GGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKD---------AFRKTWNP
KYTLRSHFDGVRALAF----HPVE---PVLVTASEDHTLKLWNLQK--------------
-TVP--AKKSASL-DVEP------IYTFRAHIGPVLSLAISSNGEQ------------CF
SGGIDATIQWWNMP-SPNVDPYDTY---------------------------EPNVLAG-
-TLVAHTDAVWGLAY-----------------SGIKNQ---LLSCSADGTVRLW------
---------------------------------NPPEKLPCICTYNGDKEHGI-------
--PTSVDFIGCDPAHMVTSFNTGSTVIYDLETSQSLLMLSSQVDSGLQSNN---HINRVV
S-----------------------------------HPTLPVTITAHEDRHIKFFDNKTG
--KMIHSMVAHLDAVTSLAVDP-NGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDE
--SIYDVAFHPS---KAYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|50309993|ref|XP_455010.1|	Kluyveromyces lactis
----------------------------------MSSNGKQQGNKAGDAAGGA-------
---------------------------SGATAPGAGGSSGNGNS-------SAAGNASAN
ANA-------GGSGA---------SGNAPAA----------SKPGF----------SAS-
------------------------------------DLNRIVLE----------------
-----------------------YLNKKGYHRTEQMLRAESSRTLTPPNKNAAASNTIPA
SSASATAIT-----------------GSTTTAKPVSNPSMPLKRDNN-----GQLIKPQQ
VTPLH----------YF-------------RAYSMLKNWIDSSLELYKPELSRIIYPIFI
YVFLQLVIKDPLQ--ARRFFDKYSVDYKALHGSEINRLFSVNSVDHIKE-----------
--------NELAQGFQ----------------------TNKYKITISRTTLNLLLYFLNE
NESVGGSLLIS-----IINQNLDPNIVDVVKS------EDI-LTDGIKDISTGDIDV---
----------DTYNSVPVKLGPYPKDEEFTKEVEIELQKKDEQEAAENKDKPVGKTLVEE
YREMNGNQNKPEG--------------------------------TEKADDNT------V
KEENENKEPEAEE-----------------------------------------G-----
-------GEEVDATADTEEKGTPTLSVESSAAERKKRDSKNKD------------EEEKP
EASIGSMME-----------SPAKDSLPLPVKTTLDLKMEIQKVRE--------------
------SRDSIQLKNLQTSAPSVCMYTFHNTNGNMTCVEFSDDARL------------TA
AGFQDSTIKVWYLD-GSPLQSILPS---------------------------KAKDQSNS
ATLVGHSGPVYSVAF-----------------SPDNRY---LLSASEDKTVRLW------
----------------------------------SLDTFTCLVCYKGHNH----------
--PVWYVKFSPLGHYFITASHDQTARLWSCDHIYPLRIFSGHLNDVDCSTF---------
------------------------------------HPNGCYVFTGSSDKTCRMWDIQTG
--DSVRLFLGHTSPVTALEVSP-DGRWLTTGSEDGTIIVWDIGTGKRIKQMKGHGKN---
--PIYSITFNKE---GNCLVTGGADQSVRVWDIKRFTNEPGMEPEQQFNTYSGDMELSVN
NDIKEFGRRRAVIPTQDLMASFHTKKTAIHKVKFTRTNLVLAGGAFIE
>gi|125830119|ref|XP_700885.2|	Danio rerio
-------------------------MASFGKLTDYFNRRRSRDELMARRDARR-SGSYCC
TVAEARSLERRLQRPLLAKSRTLPSIPQSPAAVRVQQTESDCERQQRPRVPSSPGGLEAC
TIP-------PAGEM---WRLEDESEADMAPGAVDLRPRSQSPFSHFRRRAAYLRKSIS-
----------------ADDHLVDSEFQSIQTEDRSSADPKAKLKR---------------
-------------------KFAQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKFH
KLKYGTELN------------------QGDMKPPSYDSDDGNENEAL---------PEPA
NSQLS----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVKSQRV
KALLGLCGET----------GGDARDEPMVN-GTEP--ASLKDSTHTMIGKAEMSDS---
--------ATVMKAFKFIEKAAAEFSD-EEE-------DEDSE-----GQNRSIVD-LAT
---MVRRKVSPSPSSSSTDVSEDLDTDEVLKG------FDF-LANTEDMME-GQTQDTPA
AGDW------EKEEQSPLCESWDVDEGLISKLKEQYKKERKGKKGVKRPNRCKLQDMLAN
LRDAEDLSSIQPP--------------------------------VAPPARPSL---PRL
NEHQLGRTDEVEAMTFPPSSGKSFIMGTDEALENELGLGELAGLTVANEAEMEAMTFPPS
SGKSFIMGTDEALENELGLGELAGLTVANEAESLSYDITNNKD---------ALRKTWNP
KFTLRNHFDSIRGLAF----HPVE---PVLITASEDHTLKMWNLQK--------------
-TAP--TKKCAAL-DVEP------IYTFRAHRGPVLCVVMSSSGEQ------------CF
SGGLDGTIQSWNTP-NPNIDPYDSY---------------------------------G-
------------------------------------TR---LLSCSADGTVRLW------
---------------------------------SAADTEPAIACFNTNKELGV-------
--PSSVDVVCSDPAHMVTAFSNGRTGIYNMETRQLILELESQSAGKPDAPC---QINKVL
S-----------------------------------HPTLPITITAQEDRHIRFFDNNTG
--------------------------------HDCSVRLWNMESKTCIQEFTAHRKKFDE
--SINDVAFHPS---KCYIGSAGADALAKVFV----------------------------
------------------------------------------------
>gi|83768267|dbj|BAE58406.1|	Aspergillus oryzae
------------------------------------------------------------
--------------------------------------------------------MVG-
-AG-------GYGGP----------GDGSSNGGQP------QGTEY----------TLQE
TLPRHDNETNHFGASSGVMRFLQTEWHRHERDRNAWEIERAEMK----------------
---------------------SRIGKLEGDVRTSKRLHESLGKHVRLLEAALKKEREKVK
KLSNNEKVEDTRDPKD-IARESINALKSQRPKLPMELNE----AELN-----DSQPDFRQ
ENERE-------------------------KSRLYLSKCSQ---EVTYH-VIPASHPPPE
LSDPELPNHIYGN---------QQLSQQALEEAYHI------------------------
--------------------------------------QQQRQKQQQQQQQANHMM-ARE
VSLQNHQPIVA-------QYSESSGIARQPNQ------FGLPPGSREALERKPLEPRQTP
ATAV------DSRKQAPEHTIVDERTGAEKQAYEVYGAQGGVKEEIQPQQAEQQQQEDSD
GWNFDEPSEKEPP--------------------------------TEPMPP------HRP
DVDAFPNANFVRP-----------------------------------------K-----
--------SPSRSGSLSHRRKSSGARSKSEGSSDSIGGAAQKQ-----------DTNFKV
RFALRGHLDVVRSVIFTGGGSPSE---PEICTCSDDGTIKRWIIPA---------TYGNF
GSHN--ANSSNDL-DITS------YFTHRGHVGAVTALAACSPSRDFSNGGRALGDGWVF
SGGQDASVRVWE---RGRIDP------------------------------------KA-
-TLDGHTDAVWGLCVLPGTTGSVFGDSCGHYGGPDRIL---LASGAADGQILIWAVSAPP
QLSSPQAGNRR----AGGSRRANSISSGSNFPSSPQPSMATSTPFHYTLIHKITRKD--S
PSPTCISPLSLAGVNFVVSFSDASIIVYDTRTGEEIVGMASLETYDGTPST---GVNSVV
ATTVGFDGSAGLDPSRISGEEEVVHGATGS------SGVEGVIISGYEDRYIRLFDANSG
--QCTYTMLAHPSAIASLSLSP-DGRELVSAGHDASLRFWNLEKRSCTQEITSHRLMRGE
--GVCSAVWSRD---GRWVVSGGGDGLVKVFSR---------------------------
------------------------------------------------
>gi|109102629|ref|XP_001107812.	Macaca mulatta
-----------------------------------------MDEQAGPGVFFS-------
---------------------------------NNHPGAGGAKG-------LGPLAEAAA
AGD-------GAAAA------------AAAAGA--------ARAQY----------SIL-
----------------GVAN-MHHSPERFK-ERTRGNVSLLNIQ----------------
---------------------AQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDMKPPSYDSDEGNETEVQ----------PQQ
NSQLM----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVKSKRV
RALLGFSSDVTDR-------EDDKNQDSVVNGTEAE--VKETAMIGKSELTDS-------
--------ASVLDNFKFLESAAADF-------------SDEDEDDDLDGREKSVID-TST
---IVRKKALS-------DSSEDRDTKEALKE------FDF-LVTSEEGDN--ESRSAGD
GTDW------EKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LRDVDELPSLQPS--------------------------------VGSPSRPSS---SRL
PEHEINRADEVEA-----------------------------------------LTFPPS
SGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKD---------ALRKTWNP
KFTLRSHFDGIRALAF----HPIE---PVLITASEDHTLKMWNLQK--------------
-TAP--AKKSTSL-DVEP------IYTFRAHKGPVLCVVMSSNGEQ------------CY
SGGTDGLIQGWNTT-NPNIDPYDSY---------------------------DPSVLRG-
-PLLGHTDAVWGLAY-----------------SAAHQR---LLSCSADGTLRVW------
---------------------------------NTTEVAPALSVFNDTQELGI-------
--PASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTTANSSC---QINRVI
S-----------------------------------HPTLPISITAHEDRHIKFYDNNTG
--KLIHSMVAHLEAVTSLAVDP-NGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEE
--SIHDVAFHPS---KCYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|73621961|sp|Q70M86|STRN_SOR	Sordaria macrospora
------------------------------------------------------------
-----------------------------------MGTNGVHVS-------FGAGHEMGG
VMG-------NGSGQ-----------------P--------PATEY----------TLQ-
----------------GVMRFLQTEWHRHERDRNAWEIEKQEMR----------------
---------------------ARIANLEGQARRADATQKALKRYVSILEKKVKEQSAALK
SGGKEKGVEDEAEAEDNKTKLDRSALIQEKLRPNTKLSGAPNEAENV------EIGPPDD
ESARN-------------------------ELKTFLDQCQA---EFTYL-MVTPANPQPP
RESPPLPILDDFR--------EGEALNQQLEQSYQR------------------------
--------------------------------------SQQSQIRDLLAQQAAAAN-ATN
VAAVQSQQQQP-------QQQQHAVGPRPQTN------QPP-KGYGELAQGAPMERSSRG
QQLHDILKSGETPDWSASMQSQPVEEPTSALSKAPPMVRGDGREPAVPKSAS-----TTD
AWDFNESNFQDPN--------------------------------AMPQPTPQQSFSSRP
DTDAFPSAEN--------------------------------------------------
-----LTKSPNRGALSHRRKSSSGMARRRSAE-HELSLGSLQQ--------KAEGTMFKF
RFGLRGHLDVVRTVIFSGGGSPGE---PEICTAGDDGLVKRFHIPD--------------
-RHIGQRNADGDL-DVAA------DFTHRGHSGAVLSLASWSPSPNFSTGGRAQGDGWIF
SGGQDATIRVWE---RGRVDP------------------------------------KA-
-TLDGHTDAVWALCVLPTNLGAIFGQTNS-HGPPDRIL---LVSGAADGTVKVWAVSAPP
QLTSPQPGPGR--RGPGGRVRGNSMSSGSAFPSSPQPTTASNSPFHHTLVHTIKRAN-SE
ASPTCITALSPNGETFAVSYADAAIIVYDTRSGEEIGTMASLDTYDGTNNT---AVNAVV
ATTVGLD-QTQ----GPGGEDESGGGPTGGGRSMAGSGVEGTIISGHEDRYIRFFDANSG
--QCTYNMLAHPGSVSSLSLSP-DGRELVSAGHDMSLRFWSLETRSCTQEMTCHRSMRGE
--GVCAVVWSQD---GRWVVSSGGDGMVKVYAR---------------------------
------------------------------------------------
>gi|157016755|gb|EAL40293.3|	Anopheles gambiae
PANGGHVMRINRIEDRMDDNSSLGHQNG-------GGSAVGQLGGIGGGAGGGQGGG---
---------------------------TGGLGDMSGGGGAGS------------------
--------GLVGKGG-------AGGGGGMVGAGQCDDQNNKTPTQY----------SIP-
----------------GILHFIQHEWARFELERSQWDVDRAELQ----------------
---------------------AKIAVLVGERKGQESLKSDLIRRIKMLEYALKQERAKFH
RLKYGVDPP------------------MNDIKPPTDEPGIGTEVAPD------PEVPYSS
VSNIT----------WR-------------QGRLLLRQYLQ---EIGYTDTILDIRSNRV
RSLLGLNNNSEQE----------ENVNPNVNGGT--------------------------
--------------------------------------ESNKRASESQGRRTPAKK-PS-
---SVTEAMIL-------DSEA-----AVIAN------FEF-LAREDVEMS---------
----------DDDDVSDEIDVVGDSEDTDMKTT---KRKAKGSTLN--------------
------------------------------------------------------------
------------------------------------------------------------
---------DVEVDSSLG--ELAQLTVNNETE-SGYDVSNSKE---------PYRKTWNA
KYTLRSHFDGVRALAF----HPQE---PVLITASEDHTLKLWNLQK--------------
-TVP--AKKSASL-DVEP------LYTFRSHSGPVLCLAMSATGEQ------------CY
SGGLDGAINCWNLP-SSNIDPYDSY---------------------------DPEVMRC-
-TIDGHTDAVWGLAV-----------------NHAKNT---LVSCSADGTVKLW------
---------------------------------SPSGKIPTNSTTFTSETEGV-------
--PTSVDFVKDQIDRIVVAYSSTHCIIYDTETGKQVVKLEASQEMTGNLGK---HINKVI
S-----------------------------------HPTLPVTITAHEDRHIRFWDNGTG
--SLVHSMVAHLDAVTSLAIDA-HGLYLLSGSHDCSIRLWHMDNKTCVQEITAHRKKFDE
--SILDVAFHPS---KPFIASAGADAIAKVFV----------------------------
------------------------------------------------
>gi|47225047|emb|CAF97462.1|	Tetraodon nigroviridis
------------------------------------------------------------
-------------------------------GPKAAPGPATSAT-------ATGAMAAAA
AAA-------AAAGA----------GPGTSHNRELQD----GDSGM----------TLP-
----------------GILHFIQYEWGRFQAEKYRWEAERDELRGCGRASQRGLLVLSNR
VSRFSLLTPLLHEAFQVFITSAQVAFLQGERKGQESMKQDLVRRIKMLEYALKQERAKHQ
KLKTGSDQS------------------PGDKKTEAESEQVPNGPAEP---------DSEP
ANQMS----------WK-------------EGRQLLRKYLE---EVGYSDTILDMRSKRV
RSLLGRSSPEANG-----PPPETCQEPEPHSGGESLLVRQIEEQIKRNAGKESSKERLG-
--------GSVLDKIPFLHGCEDDEEDDSDE-------EDDFQGMATDCIDGPRKN-KKS
RVKVTRGNLDP------EDEEDEDDSEDALGE------FDF-LGSGEDGEGAGEARISGD
GREL-------------------------------------------ENHRNKLQGMMSD
F---PSKPAKPPS--------------------------------VSGPARSG-------
EGGALGFSSEVFI-----------------------------------------M-----
---------DAVGGGDMNLGELADLTVANDND-LSMDMQDNRE---------EFKKTWNP
RFTLRSHFDAIRALTF----HPGQ---AVLLTASEDGTLKLWNLNK--------------
-AMH--SKKNAAL-DVEP------IYTFRAHSGAVLSLTMGENGDS------------CY
SGGLDGSVRCWKMP-DLNVDPYDNYGQPSSAATVQPSRSPFSRGVTRPPLRPDPGIESS-
-VLAGHEDSVWGLTY-----------------STFHHR---LASCSADGTVRIW------
---------------------------------DPQNSEPCLSVFNKEREHGT-------
--PTSVAFVATDPNQVVVSFDGGETVLYDLTTEQSTTALETQTKDGSE------LINRVV
S-----------------------------------HPSEPVSITAHENRTIRFLDNNTG
--KVVHSMVAHLDAVTCLTTDP-KGTYLISGSHDCSVRLWMLDNRTCVQEITAHRKKHDE
--AIHDVAFHPC---QPFIASAGADALAKIFV----------------------------
------------------------------------------------
>gi|67971972|dbj|BAE02328.1|	Macaca fascicularis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----M----------WK-------------QGRQLLRQYLQ---EVGYTDTILGVKSKRV
RALLGFSSDVTDR-------EDDKNQDSVVNGTEAE--VKETAMIGKSELTDS-------
--------ASVLDNFKFLESAAADF-------------SDEDEDDDLDGREKSVID-TST
---IVRKKALS-------DSSEDRDTKEALKE------FDF-LVTSEEGDN--ESRSAGD
GTDW------EKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LRDVDELPSLQPS--------------------------------VGSPSRPSS---SRL
PEHEINRADEVEA-----------------------------------------LTFPPS
SGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKD---------ALRKTWNP
KFTLRSHFDGIRALAF----HPIE---PVLITASEDHTLKMWNLQK--------------
-TAP--AKKSTSL-DVEP------IYTFRAHKGPVLCVVMSSNGEQ------------CY
SGGTDGLIQGWNTT-NPNIDPYDSY---------------------------DPSVLRG-
-PLLGHTDAVWGLAY-----------------SAAHQR---LLSCSADGTLRVW------
---------------------------------NTTEVAPALSVFSDTQELGI-------
--PASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNVDTT-NSSC---QINRVI
S-----------------------------------HPTLPISITAHEDRHIKFYDNNTG
--KLIHSMVAHLEAVTSLAVDP-NGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEE
--SIHDVAFHPS---KCYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|115653051|ref|XP_782795.2|	Strongylocentrotus purpuratus
-----------------------------------------MD-----------------
---------------------------------------------------SESGLSQNH
VNQ-------MNSGS--------SSVNSISSKQQDDH----PRPNY----------TIP-
----------------GILHFIQHEWARFEMERAQWEVERAELQ----------------
---------------------ARIAFLQGERKGQENLKHDLVRRIKMLEFALKQERTKYQ
KLKSGSD--------------------KDELKAPTFDGEEGGQEESA---------LSPN
SVNFR-------------------------QSRQLLRQYLQ---EIGYTDTILDIRSNRV
RSLLGLAPNERTG----PGLETNGQIEPIVN-GESP--AKQGRHIEQGTTKRQHEKPRMH
QALPENVLDKVLSTFDFLSDTLDDDGEVEGDGEEGITADDESDIRESRGKTGTIVKKKKQ
V--VGNEGMAG-----MGEDEDDPDTEEALAE------FDF-LVA-EQSEGAGEARTA-E
GPEWTIGAGKKGVDLSPTGEEWGVDQGMLNKLKEEYKKSRRNKGIDRRPNKAALQAMLAN
LDDVSPPASNTPGGSSRSRGADIDITDEAGPNKAALQAMLANLDDVSPPASNTPGGSSRS
RGADIDITDEADV-----------------------------------------AVAPRQ
G----IMGADEEALETLRLGELAGLTITNEADVLSYDISANKE---------TFRKTWNP
KFTLRSHFDGVRALVF----HPEE---PVLITGSEDNTLKLWNLQK--------------
-TVP--AKKAASL-DVEP------IYTFRGHVGAVLSLAVSSNGEQ------------CF
SGGMDSSIRCWNIP-GSNIDPYDLY---------------------------DPSVMAE-
-TYVGHTDAVWGLSY-----------------DGTKNS---LVSCSSDGTVKLW------
---------------------------------SPGKKSPLLTTITAETAFGV-------
--PTSVDFVRCDTSQITVGFSSADVAVYDLETAKKVITLDSRLPSD-SPTS---QINSVA
S-----------------------------------HPTLPVTITAHEDRHIRFFDNNSG
--KMVHSMVAHLDAVTCLAVDP-NGLYLLSGSHDSSIRLWNLDSKTCVQEITSHRKKFDE
--SIFDVAFHPS---KPYIASGGADALAKVFV----------------------------
------------------------------------------------
>gi|156542927|ref|XP_001601585.	Nasonia vitripennis
----------------------------MKVPIHQFYSTRTMEENSGSISSSSSV-----
---------------------------GSAQNHNGGGQPFGGVN-------VSAANNKHQ
SGG-------GENDG---------SGAGPQGQGGPASKE--QNPQY----------TMP-
----------------GVLHFLQHEWARFELERSQWELDRAEFQ----------------
---------------------ARIAFLQGERKGQENLKTDLVRRIKMLEYALKQERAKYH
KLKYGTDLV-----------------IQGDGKPAYDEGSTCTGTEGG---GGDGEAPFTS
VSNIS----------WR-------------QGRQLLRQYLQ---EIGYTDTIIDVRSNRV
RSLLGLNNNTDSE----------DTNTPALNGNESRVESNKRANEYK-------------
--------------------------------------NTKFKNTSPRKEQQPS------
---SIAEAMIL-------DTEA-----AVMAN------FEF-LAHTDIDM----------
----------EEEENDGEEEIYDSKTD---------AKQNKASILLSEDVDAEAEEVLNE
LNLLTESEESIIH--------------------------------VDMDTNDWN------
---AVRRGMQPDP-----------------------------------------R-----
-------RPCEEGGSSLGLGELAQLTVNNDAE-AAYDVSSEKS-----NNEEPFRKSWNA
KYTLRSHFDGVRALVF----HPTD---PVLITASDDHTLKLWNLHK--------------
-TVP--AKKSASL-DVEP------LYTFRSHTGPVLCLAMDSNGSH------------CF
SGGLDGKIHCWALP-SANIDPYDSY---------------------------DPSLLNQ-
-TLTGHTDAVWGLSM-----------------CHPRSQ---LLSVSADGTVKLW------
---------------------------------SPASKTRLLNTYTSEQDRN--------
--PTSVDFIRDEPHKLVVAYEEA-CVIFDAETGSIVSRLE------GDETQ---GVNRLV
A-----------------------------------HPILPLVVAANEDRHIRFYDHRSA
--TLAHAMVAHLDAVTSLAVDP-NGLYLLSGSHDCSIRLWNMDNKTCVQEITAHRKKFDE
--SILDVAFHPS---RPFIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|61744137|gb|AAX55652.1|	Gibberella moniliformis
------------------------------------------------------------
------------------------------------MGPNAGNG--------VGGLEMGP
MMQ-------GNGSN----IP--------------------QATEY----------TLQ-
----------------GVMRFLQTEWHRHERDRNSWEIEKQEMK----------------
---------------------GRIANLEGQARRADATQRVLRKYVTMLERKVKEQTAQL-
QAREAVDAETAAKNDRAAKIQEKLRSTLEDMPVPGVDGVNYEKLDRG-----------DE
EAQRQ-------------------------DLKTFLDQCQS---EFMYL-MITPANPQPP
RESPPLPIMEDLR-------------EVEAFGMPAP--QQQFQLPTRNA-----------
----------------------------QNH-------SQEMNSRISQQNHAPPSQ----
------------------------------NQ------QQH-FGQKQEHQPQPMVRSEHP
PVMYQ-----NSNDWPAPVSVTSRPVEDHMPQANHAAEVLGGMDDSAELREKHSAQPEND
GWEFPEGTFPEPG--------------------------------NSQPNSQP----NRP
DTDAFPTADNLPK-----------------------------------------S-----
---------PSRRDSSHRRK--GSMSRRRSAD-HELALAAQK----------AESGNFKL
RFGLRGHLDTVRTIIFSGGGSPGE---PEICTGGDDGMIKRFHIPR------------LD
GHPGGLAHTASDL-DVTA------NFTHRGHAGAILCLTSWSPSPNFSTGGRAQGDGWIF
SGGQDATIRVWE---RGRVDP------------------------------------KA-
-TLEGHTDAVWAICVLPATLGQIFGSSSP-YGSTDRIL---VVSGAADGSVRLWSVSAPP
QLSSPQPGTNRAMTGRGGRVRGNSMSSGSGFSNTPQPTIASNSPFNHTLVHNISRSDGST
ASPTCITPLGTTGESFVVSYSDAAIIVYDTRTGEQIGNMDSLETYDQSNKT---SVNAVV
ATTIGLD-QANQNHSGSIGEEDASPGATGGGRSMAGSGVEGTIISGHEDRFIRFFDANSG
--QCTYNMIAHPDAISSLSLSP-DGRELVSAGHDASLRFWSLEKRTCTQEVTSHRVMRGE
--GICACVWCQD---GKWVVSAGGDGVVKVFAR---------------------------
------------------------------------------------
>gi|142976686|ref|NP_001077362.	Homo sapiens
-----------------------------------------MDELAGGGGGGP-------
---------------------------GMAAPPRQQQGPGGNLG-------LSPGGNGAA
GGG-------GPPAS---------EGAGPAAGPELS-----RPQQY----------TIP-
----------------GILHYIQHEWARFEMERAHWEVERAELQ----------------
---------------------ARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDLKMPTFESEETKDTEAP---------TAPQ
NSQLT----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVRSQRV
RSLLGLSNSEPNG------SVETKNLEQILNGGESP--KQKGQEIKRSS-----------
--------GDVLETFNFLENADDSD---EDE-------ENDMIEGIPEGKDKHRMN-KHK
---IGNEGLAA-------DLTDDPDTEEALKE------FDF-LVTAEDGEGAGEARSSGD
GTEW------DKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKRANRTKLYDMIAD
LGD-DELPHIPSG--------------------------------IINQSRSAS---TRM
TDHEGARAEEAEP-----------------------------------------ITFPSG
GGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKD---------AFRKTWNP
KYTLRSHFDGVRALAF----HPVE---PVLVTASEDHTLKLWNLQK--------------
-TVP--AKKSASL-DVEP------IYTFRAHIGPVLSLAISSNGEQ------------CF
SGGIDATIQWWNMP-SPSVDPYDTY---------------------------EPNVLAG-
-TLVGHTDAVWGLAY-----------------SGIKNQ---LLSCSADGTVRLW------
---------------------------------NPQEKLPCICTYNGDKKHGI-------
--PTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVILSSQVDSGLQSNN---HINRVV
S-----------------------------------HPTLPVTITAHEDRHIKFFDNKTG
--KMIHSMVAHLDAVTSLAVDP-NGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDE
--SIYDVAFHSS---KAYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|19111908|ref|NP_595116.1|	Schizosaccharomyces pombe
------------------------------------------------------------
---------------------------------------------------MKSNLSLKR
QDE-------KRADK--------------------------EPNLY----------TLQ-
----------------GVIQYLQYEAFKNERDHNLWEIERAELK----------------
---------------------IRVAQLERERAKLEQSLSFQQRRAEMLEKSLRE------
-LRKDKNIS-----------------VKDLDEFHLLDKPAANNTKAD------------A
EACLL-------------------------KSKNYIKKSLQ---EIVY---LTNMQPNVS
WNVLQ----EPTR------------------GIKVPKESNNT------------------
------------------------------------------------------------
--QQNNQFVM--------EPSQNKGNVNDANF------FEVEYARNENM-----------
----------NKLSSSELISDDLLEDEIMKPLSSGESLPKKEEEVTKSP-----------
------------------------------------------------------------
------------------------------------------------------------
-----SFTLDDSVASNEQ--TLAQLNIESPVDQKKSKAKKKKE------------QKWTL
KFE-SDKGTSTQCITH----QPLPGSTPSFASGTENGVINVWRLDE--------------
------DSNDNSMGIIKP------HLTFYGHEGPVLCVCVPKATHH------------IF
SGGHDGTIRCWSLP-ANQTSDS------------------------------ISKILTGS
TIFQGHEDCVWELFC-----------------HEVKDNNPILLSLSSDGTVRGW------
-------------------------------------KYTGEQLFKIRCDSKQ-------
--PLSMSVTD---SRIAIAYNDGNVRFYDLDTQILVSQMRIAGNSAIGNPAVKDRINKIV
WK----------------------------------NGNPDRLYSLHENGMVRVFDVKSE
--ELLAEKSISKVSLTGIAFAV-NRPEFAISASDGRVFFLRQDDKLSTLESLPSREAQEE
ITDLSDILWINSPVDKLEHLIVGCKERISVYDRKYLP-----------------------
------------------------------------------------
>gi|16418469|ref|NP_443205.1|	Mus musculus
-----------------------------------------MDELAGGGGGGQ-------
---------------------------GMAAPPRPQQGPGGNLS-------LPPGANGAP
GGG-------GPPAA---------EAAGPPAGPELS-----RPQQY----------TIP-
----------------GILHYIQHEWARFEMERAHWEVERAELQ----------------
---------------------ARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDLKMPTFESEETKDVEAP---------PAPQ
NSQLT----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVRSQRV
RSLLGLSNSEPNG------SVEAKNLEQILNGGESP--KQKGQEIKRPP-----------
--------GDVLETFNFLENADDS----DEE-------ENDMIEGIPEGKDKLRIH-KHK
---IGNEGLAA-------DLTDDPDTEEALKE------FDF-LVTAEDGEGAGEARSSGD
GTEW------DKDDLSPTAEVWDVDQGLISKLKEQYKKERKGKKGVKRVNRTNLCDMITD
LGD-DELPHIPSG--------------------------------IINQSRSAS---TRM
ADHEGARAEEAEP-----------------------------------------ITFPSG
GGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKD---------AFRKTWNP
KYTLRSHFDGVRALAF----HPVE---PVLVTASEDHTLKLWNLQK--------------
-TVP--AKKSASL-DVEP------IYTFRAHIGPVLSLAISSNGEQ------------CF
SGGIDATIQWWNMP-SPNVDPYDTY---------------------------ESNVLAG-
-TLVAHTDAVWGLAY-----------------SGIKNQ---LLSCSADGTIRLW------
---------------------------------NPQEKLPCVCTYNGDKEHGI-------
--PTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVMLSSQVDSGLQSSN---HINRVV
S-----------------------------------HPTLPVTITAHEDRHIKFFDNKTG
--KMIHSMVAHLDAVTSLAVDP-NGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDE
--SIYDVAFHPS---KAYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|157111516|ref|XP_001651599.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------AKIAVLLGERKGQESLKSDLIRRIKMLEYALKQERAKFH
RLKYGVDPP------------------MNDIKPPSDDPGIGTEVAPD------PEVPYSS
VSNIT----------WR-------------QGRQLLRQYLQ---EIGYTETIIDIRSNRV
RSLLGLNNNSEQE----------ENVNPNINGGSET------------------------
----------------------------------------NKRASESQGRRTPAKK-SQP
S--SMTEAMIL-------DSEA-----AVIAN------FEF-LTQADTEMS---------
----------DDDDMSD-------EIGENEETDMKTTKRKAKATLNDDDVDAEADEVINE
LNLLTEGEDSNLT--------------------------------ENRKADGGDLF-VGY
NKPAIPRHPTIPG-----------------------------------------I-----
-------TSDEEVDSSLGLGELAQLTVNNEAE-STYEVSNTKE---------PYRKTWNA
KYTLRSHFDGVRALAF----HPQE---SVLITASEDHTLKLWNLQK--------------
-TVP--AKKSASL-DVEP------LYTFRSHNGPVLCLAMSANGEQ------------CY
SGGLDGAINCWNLP-NYNIDPYDSY---------------------------DPEVMRC-
-TLDGHTNAVWGLAV-----------------NHTKNS---LVSCSADGTVKLW------
---------------------------------TPSGKIPQLNNTFTSETEGI-------
--PTSVDFVRDQTDRIVVAYSSTHCLIYDTETGRQVVKLEASQEMTGNVGK---HINKVI
S-----------------------------------HPTLPITITAHEDRHIRFWDNTTG
--SLIHSMVAHLDAVTSLAIDA-HGLYLLSGSHDCSIRLWHMDNKTCVQEITAHRKKFDE
--SILDVAFHPS---KPYIASAGADAIAKVFV----------------------------
------------------------------------------------
>gi|119903351|ref|XP_617163.3|	Bos taurus
-----------------------------------------MDEQAGPGVFFS-------
---------------------------------NNHPAAGGAKG-------LGPLAEAAA
AGD-------G----------------VAAAGA--------ARAQY----------SLP-
----------------GILHFLQHEWARFEVERAQWEVERAELQ----------------
---------------------AQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDMKPPSYDSDEGNETEVQ----------PQQ
NSQLM----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVKSKRV
RALLGFSSDVTDR-------EDDKNQDSVINGTEAE--VKETAMIGKSELTDS-------
--------ASVLENFKFLESAAADFSD-EDE-------DDDID-----GREKSIID-TST
---IVRKKVLP-------DSSEDRDTKEALKE------FDF-LVTSEEGDN--DSRSAGD
GTDW------EKEDQCLMPEAWNVDQGVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LRDVDELSSLQPS--------------------------------VGSPSRPSS---SRL
PEHEINRADEVEA-----------------------------------------LTFPPS
SGKSFIMGADEALESELGLGELAGLTVANEADSLTYDIANNKD---------ALRKTWNP
KFTLRSHFDGIRALAF----HPTE---PVLITASEDHTLKMWNLQK--------------
-TAP--AKKSTSL-DVEP------IYTFRAHKGPVLCVVMSSSGEQ------------CY
SGGADGLIQSWNTT-NPNIDPYDSY---------------------------DPSVLRG-
-PLLGHTDAVWGLAY-----------------SAAHQR---LLSCSADGTLRLW------
---------------------------------NTTEVAPALSVFNDNQELGV-------
--PASVDLVSSDPSHMVASFSKGYTSIFNMETQQRILTLESNLDSTANSSC---QINRVI
S-----------------------------------HPTLPISITAHEDRHIKFYDNNTG
--KLIHSMVAHLEAVTSLAVDP-NGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFEE
--SIHDVAFHPS---KCYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|149692820|ref|XP_001489557.	Equus caballus
-----------------------------------------MDELAGGGGGGP-------
---------------------------GMAAPPRQQQGPGGNVS-------LSPGGNGAA
GGG-------GPPAA---------EGAGPAAGPELS-----RPQQY----------TIP-
----------------GILHYIQHEWARFEMERAHWEVERAELQ----------------
---------------------ARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDLKMPTFESEETKDTEAP---------TAPQ
NSQLT----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVRSQRV
RSLLGLSNSEPNG------SVEAKNLEQILNGGESP--KQKGQEIKRPS-----------
--------GDVLETFNFLENADDSD---EEE-------ENDMIEGIPEGKDKHRMN-KHK
---IGNEGLAA-------DLTDDPDTEEALKE------FDF-LVTAEDGEGAGEARSSGD
GTEW------DKDDLSPTTEVWDVDQGLISKLKEQYKKERKGKKGVKRVGRTKLDDMVAD
LGD-DMLPHIPSG--------------------------------IINQFRSAS---TRM
TDHEGARAEEAEP-----------------------------------------ITFPSG
GGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKD---------AFRKTWNP
KYTLRSHFDGVRALAF----HPVE---PVLVTASEDHTLKLWNLQK--------------
-TVP--AKKSASL-DVEP------IYTFRAHIGPVLSLALSSNGEQ------------CF
SGGIDATIQWWNMP-SPNVDPYDTY---------------------------EPNVLAG-
-TLVAHTDAVWGLAY-----------------SGIKNQ---LLSCSADGTVRLW------
---------------------------------NPQEKLPCICTYNGDKEHGI-------
--PTSVDFIGCDPAHMVTSFNTGSTVIYDLETSQSLVMLSSQIDSGLQSNN---HINRVV
S-----------------------------------HPTLPVTITAHEDRHIKFFDNKTG
--KMIHSMVAHLDAVTSLAVDP-NGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDE
--SIYDVAFHPS---KAYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|118091801|ref|XP_421225.2|	Gallus gallus
-----------------------------------------MDEHPGAGGGGGMA-----
---------------------------AAPRPQQPPPQSGGNVN-------LQPGGGCAG
AGA-------GGGGQQQPQGPAAPGGQEAAGPAELS-----RPQHY----------TIP-
----------------GILHYIQHEWARFEMERAHWEVERAELQ----------------
---------------------ARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDLKMPTFESEETKDTEVP---------AVPQ
NSQLT----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVRSQRV
RSLLGLSNSEPNG------SVETKNLEQILNGGESPSSKQKGQEIKRNS-----------
--------GDVLETFNFLENADDSD---EEE-------ESDMIEDIAEGKEKHRINKKHK
---IGNEGLAA-------DLTDDPDTEEALKE------FDF-LVTAEDGEGAGEARSSGD
GTEW--------------------------------------------------------
------------------------------------------------------------
----------AEP-----------------------------------------ITFPSG
GGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKD---------AFRKTWNP
KYTLRSHFDGVRALAF----HPVE---PVLVTASEDHTLKLWNLQK--------------
-TVP--AKKSASL-DVEP------IYTFRAHIGPVLSLAISSNGEQ------------CF
SGGIDATIQWWNMP-SPNVDPYDTY---------------------------EPNVLAG-
-TLVAHTDAVWGLAY-----------------SGVKNH---LLSCSADGTIRLW------
---------------------------------NPPEKMPCICTYNGEKEHGI-------
--PTSVDFIGCDPAHMVASFNTGSTVIYDLETSQSVVMLSSQVESGVQSNN---HINKVV
S-----------------------------------HPTLPVTITAHEDRHIKFFDNKTG
--KMIHSMVAHLDAVTSLAVDP-NGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDE
--SIYDVAFHPS---KAYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|71361653|ref|NP_001025068.1	Rattus norvegicus
-----------------------------------------MDELAGGGGGQGM------
-----------------------------AVPPRPQQGPGGNLS-------LPPGAN-G-
-AP-------GGGGP------PAAETAGPPAGPELS-----RPQQY----------TIP-
----------------GILHYIQHEWARFEMERAHWEVERAELQ----------------
---------------------ARIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDLKMPTFESEETKDAEAP----------PAQ
NSQLT----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVRSQRV
RSLLGLSNSEPNG------SIEAKNLEQILNGGESP--KQKGQEIKRPS-----------
--------GDVLETFNFLENADDS----DEE-------ENDMIEGIPEGKDKLRIH-KHK
---IGNEGLAA-------DLTDDPDTEEALKE------FDF-LVTAEDGEGAGEARSSGD
GTEW------DKDDLSPTAEVWDVDQGLMSKLKEQYKKERKGKRGAKRVNRTNLCDMITD
LGD-DELPHIPSG--------------------------------IINQSRSAS---TRM
TDHEGSRAEEAEP-----------------------------------------ITFPSG
GGKSFIMGSDDVLLSVLGLGDLADLTVTNDAD-YSYDLPANKD---------ALRKTWNP
KYTLRSHFDGVRALAF----HPVE---PVLVTASEDHTLKLWNLQK--------------
-TVP--AKKSASL-DVEP------IYTFRAHIGPVLSLAISSNGEQ------------CF
SGGIDATIQWWNMP-SPNVDPYDTY---------------------------ESHVLAG-
-TLVAHTDAVWGLAY-----------------SGIKNQ---LLSCSADGTIRLW------
---------------------------------NPQEKLPCICTYNGDKEHGI-------
--PTSVDFIGCDPAHMVTSFNTGSAIIYDLETSQSLVMLSSQVDSGLQSSN---HINRVV
S-----------------------------------HPTLPVTITAHEDRHIKFFDNKTG
--KMIHSMVAHLDAVTSLAVDP-NGIYLMSGSHDCSIRLWNLDSKTCVQEITAHRKKLDE
--SIYDVAFHPS---KAYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|149412377|ref|XP_001508243.	Ornithorhynchus anatinus
------------------------------------------------------------
----------------------------------------------------------MR
LAR-------TGASS--------DEFRGISGTATT------PPPRE----------GAP-
----------------GLF---------FEAE-PPWGPRRRIGT----------------
---------------------AQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDMKPPSYDSDEGNETEVQ----------PQQ
NSQLM----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVKSKRV
RVLLGLSNDVTDR-------EEDKNQESVVNGTEAE--IKETVMIGKPELTDS-------
--------ASVLKTFSFLENAAAEF-------------SDDDEEDDIDGREKTIID-TST
---IVRKKVSP-------DTSEDRDTKEALKE------FDF-LVASDEGDG--ESRSAGD
GTDW------EKEDQCLTPEAWNVDQRVITKLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LRDVDELPSLQPS--------------------------------VTPPSRPSS---SRL
SEHETNRTDEVEA-----------------------------------------LTFPPT
SGKSFIMGTDEALENELGLGELAGLTVANEADSLTYDTANNKD---------ALRKTWNP
KFTLRSHFDGIRALAF----HPVE---PVLITASEDHTLKMWNLQK--------------
-TAP--AKKSTSL-DVEP------IYTFRAHKGPVLCVVMSSNGDQ------------CY
SGGSDGLIQGWNTT-NPNIDPYDSY---------------------------DPSVLRG-
-ALLGHTDAVWGLAY-----------------SGAHQR---LLSCSADGTLRLW------
---------------------------------NTAEMAPALSVFNDNQELGI-------
--PASVDLVSSDPSHMVASFNNGCTSIFNMETRQRVLTLESNVDPTATTSC---QINRVI
S-----------------------------------HPTLPISITAHEDRHIKFYDNNTG
--KLIHSMVAHLDAVTSLAVDP-NGLYLMSGSHDCSIRLWNLESKTCIQEFTAHRKKFDE
--SIHDVAFHPS---KCYIASAGADALAKVFV----------------------------
------------------------------------------------
>gi|149050640|gb|EDM02813.1|	Rattus norvegicus
-----------------------------------------MDEQAGPGVFFS-------
---------------------------------NNHPGAGGAKG-------LGPLAEAAA
AGD-------G----------------AAAAGA--------ARAQY----------SLP-
----------------GILHFLQHEWARFEVERAQWEVERAELQ----------------
---------------------AQIAFLQGERKGQENLKKDLVRRIKMLEYALKQERAKYH
KLKYGTELN------------------QGDMKPPSYDSDEGNETEVQ----------PQQ
NSQFM----------WK-------------QGRQLLRQYLQ---EVGYTDTILDVKSKRV
RALLGFSSDVTDR-------EDDKNQDSVINGTEAE--VKETAMIGKSELTDS-------
--------ASVLDNFKFLENAAADFSD-EDE-------DEDID-----GREKSVID-TST
---IVRKKPLP-------DTSEDRDTKEALKE------FDF-LVASEEGDN--ESRSAGD
GTDW------EKEDQCLTPEAWNVDQGVITRLKEQYKKERKGKKGVKRPNRSKLQDMLAN
LRDVDELPSLQPS--------------------------------VGSPSRPSS---SRL
PEQDISRADEVEA-----------------------------------------LTFPPS
SGKSFIMGADEALESELGLGELAGLTVANEADSLAYDIANNKD---------ALRKTWNP
KFTLRSHFDGIRALAF----HPIE---PVLITASEDHTLKMWNLQK--------------
-TAP--AKKSTSL-DVEP------IYTFRAHKS---------------------------
----------FGSK-RPSVGPH------------------------------------G-
--------------------------------------------CGVGAGLQ--------
------------------------------------------------------------
----------RGPPALVVLFSRRHSSSMD-------------------------------
------------------------------------H-----------------------
------------------------------------------------------------
---------H--------------------------------------------------
------------------------------------------------
