>gi|149037629|gb|EDL92060.1|	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MRKHRHLPLVAVFSLLLSGITMTHAQQQ-SDV
KNGAA-ADILFLVDSSWSAGKDRFLLVQEFLSDVVESLS---VGDNDFHFALVRLNGN--
PHTEFLLNAYH--SKQEVLSHI-LNMSYIGESNQTGKGLEYIIHSHLTEASGSRAADGVP
QVIVVLTDGQSEE-DGFAL-PSAELKSADVNVFAVGVEDADERTLREIASEPLSMHVFNL
ENVTSLHDMVGNLVS--CIHSSVNPERAGD-----------------------KESLKDI
TAQDSADIIFLIDGSQNTGKA-NFDVIRDFLVNVLERLSVGNQQVRVGVVQYSDEPRTMF
SLDSYP-SKAAVLDAVKRLSFAGGELANIGQALDFVVENHFTRTGGSRVEEGVPQVL-VL
ISAGPSSDEIRDAVVALKQG---SVFSFGLGAQAASRVELQHIA--TDDNLVFTVPEFRS
FGDLQEQLLPYLVGVAQRHFVLQPPAI---VTQVMEVNKRDIVFLVDGSSSLGQ-ANFNA
IRDFISRVIQRLEIGQDL----------VQVSVAQYADTVKPEFYLNTYSTKKDAITTVR
KMKALEGSALYTGSALDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDDV----SQAA
QELQKGSIMALVIGSRAADED-----------ELKEIAFDSSLVFIPAEFRPAPLQSMLP
SLMAPLRTLTGTTEVHVNKRDIIFLLDGSDNVGKNNFP-----------YVRDFVTNLVN
SLDVGS-DNIRVGLVQFSDTPVTEFSLDTYQTKSELLAHLRRLQLKGGTGLNAGSALSYV
HANHFTEAGGSRIRE----HVP--QLLLLLMAGPSEDVYLQAANALVRSGVLTFCVGTNQ
ADKAELERI-------AFNPSLVYLMDDFSA-----------LPALPQQLIQP-------
-LTTYVSGGVQEVPLSQPEVKRDILFLFDGSVNVMGQFPA-VRDFLYRIIEEL---DVKP
DGTRVAIAQFSDDVRVESRFNEHQTKAEILNLVKKMKLKTGKGLNLGLALDHALRTIFVR
SAGSRIEDNVQQFLVLLVAGRSTDAV----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------AGPA
SSLKQRGVIPFIFQAKNANPSELEQIVPSPAFILAAESLPKIGDLQSEIVGLLKAKQ--T
SDTVSGEKDVVFLIDGSEGV-RSGFPLLKEFVQRVVESLD-VGPNQVRVALVQYSDRTRP
EFYLNSHMDQQGVISAIRRLTLLGGPTPNTGAALDFVLRNILTSSTGSRIEEGVPQLLIV
LTAERSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDF--AVAIPTFRELGT
IQ--QVISERVIQLNR------------EQLSSLTPVLMPSPSAGPGNKKDVVFL-IDGS
QNAGAEFQHIRTLIERLVEYLDIGFDTTRVAVIQFSEDTKMEFPLNAHFSKDEVQNAVRR
LRPKGGR-QVYIGNALEYVLKNIFQRPLG---SRIEEGVPQFLVLISSGKSADEVDDSAV
ELKQFGVAPLTVARHTDQEELVKISLSPEYVFSVSTFRELPRLEQRLLTPITTLTSQQIQ
QILASTRYPPSVAESDAADIVFLIDSSDAMKPDGIAHIRDFVSRIVRRLNIGPNKVRIGV
VQFSNDVFPEFYLKTHKSQNSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIE
DGVPQHLVLFLGGKSQDDVSRHAQVISSSGIMSLGIGDRNIDRTDLQTITNDPRLVFTVR
EFRELPNIEER--VMLSFGPSGPTPQPPEVEF--P-SSRPEKKKADIVFLLDGSINFRRD
SFQEVLRFASEIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDF------------STKRQ
IIDAINKVIYKGGRHANTRVGIEHLLKNHFVSEAGSRLDERVPQIAFVITGGKSVEDAQD
VSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLETLHDAMH
ETLCPGVTDVSKACNLEVILGFDGSRDQNVFVSQKGLESKVDTILNRISQIQRISCSSNQ
LPTVRVSVVANTPSGPVEAFDFAEYQPDLFEKFRTMRSQHPYVLTADTLKLYQNKFRQSS
PDTVKVVIHFTDGADGDMADLYRASEELRQAGVQALILVGLERVANLERLMQVEFGRGFM
YDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGERGDRGPIGS---IGPKGISGED
-----------GYRGYPGDEGGPGERGPP---------------GVNGTQGFQGCPGQRG
VKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGR-RGDKGPKGDKGERGDV
GIRGD---------------------------------------PGDSGRDSQQRGPKGE
TGDIGPMGLPGRDGIP---------------------GSPGDPGK---------------
-------------------------------------------------------DVSTL
GCWVLLRDK---------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>gi|94732541|emb|CAK05117.1|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------C
RTAMP-ADIVFLVDDSWSVGPTSFQQIKEFIADIIRAFQGNVFGQEGIRFGVTVYSDL--
PRMRIALTDYS--TLDEVLRAV-EDVPYEGGSSRTGLALEFLEESVFSPSI-IR--ESAP
KIAVLITNGQSD--DQVDD-PAKAVADSGISLFAVGVRNADQSELKKIVTEPHEEHLMLS
PDFSFLEHLLPKLSRRICFTASEPPRPVKQ----------------KPPVVERIIGPKDL
QVSELSYSSLQLTWSQATGDVTGYRLLITPVSPKGHLLPAQQTQIDLKGDISSTPVTGLN
PKTEYSLSVYAIYPGRIGESATVATVTMKLVPVGDLLVQNATTDTVQARWSSVRGATGYR
LTWSSSE----GHIENVNLG---DNFNF---------YMVQGLH--A--GTEYTITINPI
FGDIEGPVTSAKAKTGEQRSSDSAS--------VSCKHQQRCHFLELSTRSHGIQTGLGP
DSRLISPCVLCVCVEFTG--------------------------RDRPRQLALNGSTTEY
ILKNLVHDTEYVLSLYVLFGSVVGPGITATFRTSPLGYVSNFKVTSYTSSSIHVEWSPIV
-GATEYKLTWSSEFIRPQSR------------------------YLDRSVLKHSITGLQP
NTLYSVSIHALYSN--TEGPDITLSQQ---------------------------TASLTD
SELIET-----VREVKVVDTGVSSFKLA--WKKT--------------------PGVTGY
KITWSPFHGGEKKSE----AVSSSATSFTITDLPAGSAYKIQLSAMVRSK-----EGSPV
MVTARTLDLPKVTGFSALNTTDNSTVLNWTS----------VTGVSGYLLSWRHISEVDV
-STDLLSSGFTSYKI------RDLQYGRTYIFSIRPLYGE-VEGPVTTITKRI------L
GEPRLVPVQSSTPAPVSANTKSNDMHLQTTTRNTRTPVVKAPVTASA-------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------TGQT
ASAL------------------IRMTTVNDQSILSAET-PPPGPV---------------
CGRV--KADIVFLVDESWSIGTNNFGKLKDFLFRTVTYFPSIGPKGTQIAVVHYSDQPRI
EFNFNTHKDRNSVLRALREVRYGGGNT-KTGRGISYVLREMFQESLGMR--QEAPHVLVL
LTDGRAQDDVEPPSRIAHALGVSVLVIGIAHADMEEVRTIASPTTYKNIFYASDFDDLPS
IE--REFIGSI----CSEALQSEFKQHDESAQLDTPTEDPEALAKPEGPCPLNCKGQKGE
KGDGFGHGGLR---------------------LQQGPGHFDSFSLKVKGEKGE-------
---RGLPGTDGIPGLPGRPGRTGPPGSPG---QRGPSGIP--GDMGPPG-----------
--------------NTGPKGQRGERGEPGYVMGGMEVLPGRKGEPGSSGP----------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------S
GAPGVPGVSGPPGLPGLPGPSGSPGLSIKGESGEPGPKGPRGKPGQK-------------
------------------------------------------------------------
--------GEKGEQGNNGLPGL------------------------------PGPVGVDG
LPGLAGQKGEKGQDGIGTQGAQGPPGPPGEKGN---------------------------
----TGLSGSKGEVGIQGLQGIAGPRGKKGLKGDQGEKG---------------------
---------AQGENGPIGSPG---------------------------------------
------IAGFPGAAGRKGDEGQRGAPGEPAKG----------------------------
---------------------------ILGPP----GKKGARGDIGLVGPPGPQGIKGDR
GDKGEKGNPGFGIPGQPGPKGESGERGNV---------------GLSGKPGPKGNDGSKG
DKGEIGLPGTSGSPGLRGKDGVPGLKGDTGSRGEPGSRGEPGD-RGVKGPEGHKGLKGEP
GLPGPPGV---------------------TQFTTSDNTVLTRAIKGEPG-ESGLPGPPGE
TGRPGPPGPEGKPGPPGNSLFGSSTGKDGLDGLPGIPGSKGEAGQKGEPGSK--GEKGD-
---HGRAGITGMP--------------GLPGTPGKPGVDGKRGVSGKDGERGPKGDEGEK
GVKGEPGANG---NEGQKGEQGSPGLPGPP---IVLQEGMSIEDMKKA------------
-------------------------FPLPMGPPGATG------------------PPGMK
GEKGEMGLKGEKGDAGAPGRAVEMKDIEGLFDSYG------------------------
>gi|148708137|gb|EDL40084.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MRKHRHLPLVAVFSLLLSGIATTHAQQH-GDV
KNGAA-ADIVFLVDSSWSAGKDRFLLVQEFLSDVVESLA---VGDNDFHFALVRLNGN--
PHTEFLLNTYH--SKQEVLSHI-VNMSYIGGSNQTGKGLEYVIHSHLTEASGSRAADGVP
QVIIVLTDGQSE--DGFAL-PSAELKSADVNVFAVGVEGADERALGEVASEPLSMHVFNL
ENVTSLHGLVGNLVS--CIHSSVNPERAGD-----------------------KESLKDI
TAQDSADIIFLIDGSQNTGNA-NFDVIRDFLVNVLERLSVGNQQVQVGVVQYSEEPITMF
SLNSYP-SKAAVLDAVKGLSLVGGESANIGQALDFVVENHFTRAGGSRVEEGVPQVL-VL
ISAGPSSDEIRDSVVALKQA---SVFSFGLGAQAASRAELQHIA--TDDSLVFTVPEFRS
FGDLQEQILPYLVGVAQRHIVLQPPAI---VTQVMEVNKRDIVFLVDGSSSLGP-SNFNA
IRDFVTRVIQRLEIGQDL----------VQVSVAQYADTVKPEFYLNSYTNKRDAITAVR
KMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDEV----SQPA
QELKRGSIMALAVGSKAADED-----------ELKEIAFDSSLVFIPAEFRPAPLQNMLP
SLMAPLRTLTGTTEVHVNKRDIIFLLDGSDNVGKNNFP-----------YVRDFVTNLVN
SLDVGS-DNIRVGLVQFSDTPVTEFSLDTYQTKSELLAHLRRLQLKGGSGLNAGSALSYI
HANHFTEAGGSRTRE----HVP--QLLLLLMAGPSEDAYLQAANALVRSGVLTFCVGTNR
ADKAELEHI-------AFNPSLVYLMDDFRS-----------LPSLPQQLIQP-------
-LTTYVSGGVQEVPLSQPESKRDILFLFDGSVNVLGQFPA-VRDFLYRIIEEL---DVKP
DGTRVAIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVR
SAGSRIEDNVQQFLVLLVAGRSSDAV----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------AGPA
SSLKQRGVVPFIFQAKNANPSELEQIVLSPAFILAAESLPKIGDLQSQIVSLLKAEQ--G
SGPVSGEKDVVFLIDGSEGV-RSGFPLLKDFVQRVVESLD-VGPDRVRVALVQYSDRTRP
EFYLNSHMDQQGVISAIRRLTLLGGPTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIV
LTAEPSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDF--AVAIPTFRELGT
IQ--QVISERVIQLNR------------EELSSLKPILTPSTGAGVGSKKDVVFL-IDGS
RNAGPEFQYIRTLIERIVEYLDIGFDTTRVAVIQFSEDSKMEFPLNAHFSKDEVQNAVRR
LRPKGGS-QVYIGNALEYVLKNIFQRPLG---SRIEEGVPQFLVLISSGKSDDEVDDSAV
ELKQFGVAPLTIARHTDQEELVKISLSPEYVYSVSTFRELPRLEQKLLTPITTLTSQQIH
QILASTRYPPSVVESDAADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRIGV
VQFSNDVFPEFYLKTHKSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIE
DGVPQHLVLFLGGKSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDPRLVFTVR
EFRELPNIEER--VMLSFGPSGATPQPPGVDL--PSPSRPEKKKADIVFLLDGSINFRRD
SFQEVLRFASEIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDF------------STKRQ
IIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVITGGKSVEDAQD
VSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLETLHDAMH
ETLCPGVTDVSKACNLEVILGFDGSRDQNVFVSQKGLESKVDIILNRISQIQRISCSGNQ
LPTVRVSVMANTPSGPVEAFDFAEYQPELFEKFRNMRSQRPYVLTADTLKLYQNKFRQSS
PDTVKVVIHFTDGADGDMADLYRASEELRQAGAQALILVGLERVANLERLMHLEFGRGFM
YDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGERGDRGPIGS---IGPKGISGED
-----------GYRGYPGDEGGPGERGPP---------------GVNGTQGFQGCPGQRG
VKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGR-RGDKGPKGDKGERGDV
GIRGD---------------------------------------PGDSGRDSQQRGPKGE
TGDIGPMGLPGRDGIP---------------------GSPGDPGK---------------
-------------------------------------------------------DVSTL
GCWVLLTGK---------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>gi|126322632|ref|XP_001381040.	Monodelphis domestica
MLTFAFCMFQLDRNLRSSRSGVPFHFCVLDTVTRSYPTSCITSTKKSSLTLHTDGEAEGC
RGGGPKAGALASSRVAGGEPTSLDTLSSCDGSSGLRVKSRQALPAGMVGVVNLGCPSAVG
PHLEAAFVLAARYCCHPGEGLHHFTRAITTNWFVFHVRSLLLQSVLYLDVKLLLLKLAPP
TRLRYNILSHDSIQIQWKAPKGKFSGYKLLVTPTSGGKTNQLTLQNTANKAIIQGLIPDQ
TYAVQLIAFDKDKESKPAQGQFRINDLEKRKE-PKPK-EPKPKGNGSKPSLPTEGNTFVC
KTPAI-ADIVILVDGSWSIGRFNFRLVRLFLENLVTAFN---VGANKTRIGLAQYSGD--
PRIEWHLNTFS--TKDAVIDAV-RNLPYKGGNTLTGLALNYIFENSFKPEAGAR--TGVS
KIGILITDGKSQ--DDIIP-ASKTLRDSGVELFAIGVKNADVAELQEIASEPDSTHVYNV
AEFDLMHTVVEGLTKTVCTRVEEQEKEIRG------------------SRVTNIGPPTDL
VTSEVAARSFRVTWTPAPGEVEKYRVVYYPTRG------GKPEEVVVDGTESTTILKGLM
SLTEYQIAVFAIYSTTASEGLRGTEMTLALPMASNLELYDVTENSLRVRWNAVPGASGYM
ILYAPLTEGLAGDEKEMKIG---ETLTD---------IQLKGLL--P--NTEYTVTVYAM
FGE--EASDP--VTGQEMTLPLSPP--------------RNLRISNVGANSARI--TWDP
TSKNVNGYLI-SYTTSSG---------------------------TETNEVEVDGVST-Y
SLKGLTSLTDYNVAIFSIYEEGQSEPLMGSFTTKQVPAQQYLEIDEVSEDSFRVSWKPLS
LDVAKQKLMWMPVYGGKVEQV-----------------------VLNEDQDTYVIEGLQP
GTEYEVSLLAVLSD--ESETEVLSVFGTTLEGPSTIPP----------------VTTVSP
TGPVTTVFRTGIRNLVVDDESTSSLRVK--WDISD-------------------NRVEQF
RVTYLTAKGDHAEEVIGTVMVPGKQNQLLLKPLLSDTEYKVTVTPIYSDG-----EGVSV
SAPGKTLPL-------SWGMAEQRVAYECKNITIRCVWD------ISVQTVWKHLPIEGW
TLISYQKHSKNLILF------LLLAISKDNNCKVLNTKQKGKPLCITKSYKIMFLGVTDL
EAERIQPHSLCVKWKLHSHASAYRVSIEELRDGNKQETALGGGTSSHCFYGLLADSEHKI
SVSTQLQEI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------TGPS
VSIMERTRPI------------PTPP---PATTTPLPTVPPAKEV---------------
CKAA--KADLVFMVDGSWSIGDDNFNKIINFLYNTVGALDKIGVDGTQVSIVQFTDDPRT
EFMLNTYKTKDTLLEGIKNLSYKGGNT-KTGKALKHVRDALFTAEGGTR--RGIPKVIVV
ITDGRSQDDVNKISRELQLEGISIFAIGVADADYAELVSIGSQPSARHVFFVDDFDAFKK
IE--DELITFV----C------------ETASAT---------------CPLVNK--DGN
SLAGFKMMELFGLVEK---------DFSAVEGVSMGPGTFNVYPCYQLHKDALVSQPTKY
LHPEGLP-SDYTISFLFRILPDTPQEPFALWEILNKDSDPLVGVILDNG-----------
-----------------GKTITYFNYDYQGEFQTVTF-EGPEIKKIFYGSFHKMHIVISK
TLA---------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
VFIDCKQVGEK--AVNASGNITSNGVEVLGRM--VRSRGPKDNSAPF-------------
---------------------------------------------------------QLQ
MFDIVCSTSWASRDKCCELPGL------------------------------RDEENCPA
LP----------HTCSCSEISKGASGPVGPPGG---------------------------
----PGLRGPKGQRGDQGPKGPDGPRGEAGSPGPQG------------------------
---------PPGPQGP--------------------------------------------
-------------------------SGLSIQG----------------------------
---------------------------MPGAP----GEKGEKGDLGF---PGPQGIPGST
--------------GSPGRDGSQGQRGLP---------------GKDGPTGPSGPPGPIG
IPGAPGVPGITGSTGPQGDLGPP------GLPGAKGERGERGDLQSHAMVRAVARQVCEQ
LIQSHMAR----------------------------YNSILNQIPSHSSSIRTVPGPPGE
PGRQGSPGTPGEQGPPGRPGF------------PGNPGQPGTPGERGMSKIP--STKGP-
R--VGVIKHKMWN------------------KALDPALDKLPMSH-------------QR
GTPSEPSTHA---------------LTDSP------------------------------
------------------------------------------------------------
-----------------------------------------------------------
>gi|149721636|ref|XP_001497089.	Equus caballus
-----MKIFQ--CKMQYS------------------------------------------
------------------------------------------------------------
--LFQAFLAVAYFYT------------------------------------SVQGQVAPP
TRLRYNVLSHDSIQISWKAPRGKFGGYKLLVTPASGGKTNQLNLQNTATKAIIQGLLPDQ
NYTVQLIAYSKDKESKPAQGQFRIKDLEKRKE-PKPRVKVVDKGNGSKPSSPEEVK-FFC
ETPAI-ADIVILVDGSWSIGRFNFRLVRLFLENLVTAFD---VGSEKTRIGLAQYSGD--
PRIEWHLNAFN--TKDEVIDAV-RNLPYKGGNTLTGLALNYIFENSFKPEAGAR--SGVS
KIGILITDGKSQ--DDIIP-PSRNLRESGVELFAIGVKNADENELQEIASEPDSTHVYNV
AEFDLMHTVVESLTRTVCSRVEEQDKEIKA------------------SALATIGPPTEL
ITSEVTARSFMVNWTHAPGKVEKYRIVYYPARG------GKPEEAVVDGSVSSTVLKNLM
SLTEYQIAVFAIYAHTASEGLRGTETTLALPIASDLELYDVTENSLRAKWNPVAGASGYL
ILYAPLTEGLAGDEKEMRIG---DTHTD---------IELRGLL--P--NTEYTVTVYAM
FGE--EASDP--VTGQETTLPLSPP--------------RNLRISNVGSNSARL--AWDP
SSEKISGYRI-VYNNADG---------------------------TEINEVEVDPVTT-F
PLKGLTPLTEYTVAIFSIYDEGQSEPLTGIFTTEEVPAQQYLEIDEVTTDSFRVTWHPLS
ADEGQHKLMWIPVYGGRAEEI-----------------------VLLEDQDSYVVEGLEP
GTEYEVSLLAVLDD--GSESEVVTAVGTTLDSFWT-EP----------------ATTIAP
TRPVTSVFRTGIRNLVVDDETTSSLHVK--WDISD-------------------SSVQQF
RVTYLTAQGDPAEEVVGTVMVPGSQNNLLLKALLSNTEYKVTVTPIYDDG-----EGVSV
SAPGKTLPP-------S-GPQNLRVSEEWYN-RLRISWDPPSSPVKGYRIVYKPVSVAGP
TLETFVGANINTILI------TNLLSGMDYNVKIFASQASGFSDALTGVVKTLFLGVTNL
QADQIQMTSLCARWQVQRHATAYRVVIESVQDTKKQETIVGGGTTRHCFYGLQPDSEYKI
SVYTKLQEI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------EGPS
VSIMEKTQSP------------PTQPPTFPPTV------PPAKEV---------------
CKAA--KADLVFMVDGSWSIGDENFNKIINFLYSTVGALNKIGADGTQVAIVQFTDDPRT
EFKLDAYKNKETLLDAIKHISYKGGNT-KTGKAIKHVRDTLFTEESGTR--RGIPKVIVV
ITDGRSQDDVNKISKEMQSDGYSIFAVGVADADYSELVSIGSKPSARHVFFVDDFDAFKK
IE--DELITFV----C------------ETASAT---------------CPLVHK--DGT
DIAGFKMMELFGLVEK---------DFSSVQGVSMEPGTFNVYPCYRLHTDALVSQPTKY
LHPEGLP-SDYTISFLFRILPDTPEEPFAIWEILNKNSDPLVGVILDNG-----------
-----------------GKTLTYFNYDYSGDFQTATF-EGPEVRKIFYGSFHKLHIIVNK
TLA---------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
VVIDCKQVGEK--AINASANITSDGVEVLGRM--VRSRGPNGNSAPF-------------
---------------------------------------------------------QLQ
MFDIVCSTSWANEDKCCELPAL------------------------------RDEETCPE
LP----------HSCSCSEISKGPLGPAGPPGG---------------------------
----PGLRGPKGQRGEQGPKGPDGPRGETGPPGPQG------------------------
---------PPGPQGP--------------------------------------------
-------------------------SGLSIQG----------------------------
---------------------------MPGMP----GEKGEKGETGL---PGPQGIPGAV
--------------GSPGRDGSPGQRGFP---------------GKDGSSGPPGPPGPIG
IPGAPGVPGITGSMGPQGALGPP------GVPGAKGERGERGDLQSQAMVRAVARQVCEQ
LIQSHMAS----------------------------FTAILNQIPSHSSSIRTIQGPPGE
PGRPGSPGTPGEQGPPGTPGF------------PGSAGVPGTPGERGLTGVK--GEKGNP
G--IGTQGPRGPP------------------GPAGPSGESRPGSPGPPGSPGPRGPPGHL
GVPGPQGPSG------------QPGYCDPS---SCSAYGVG-------------------
-------------------------APHPD-------------------------QPEFT
PVQDELEALELWGSGI-------------------------------------------
>gi|114621484|ref|XP_001143906.	Pan troglodytes
-----MKIFQ--RKMRYW------------------------------------------
------------------------------------------------------------
--LLPPFLAIVYFCT------------------------------------IVQGQVAPP
TRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQ
NYTVQIIAYNKDKESKPAQGQFRIKDLEKRKD-PKPRVKVVDRGNGSRPSSPEEVK-FVC
QTPAI-ADIVILVDGSWSIGRFNFRLVRLFLENLVTAFD---VGSEKTRIGLAQYSGD--
PRIEWHLNAFS--TKDEVIEAV-RNLPYKGGNTLTGLALNYIFENSFKPEAGSR--TGVS
KIGILITDGKSQ--DDIIP-PSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNV
AEFDLMHTVVESLTRTLCSRVEEQDREIKA------------------SAHAITGPPTEL
ITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRG------GKPDEVVVDGTVSSTVLKNLM
SLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYL
ILYAPLTEGLAGDEKEMKIG---ETHTD---------IELSGLL--P--NTEYTVTVYAM
FGE--EASDP--VTGQETTLALSPP--------------RNLRISNVGSNSARL--TWDP
TSRQINGYRI-VYNNADG---------------------------TEINEVEVDPITT-F
PLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLS
ADEGLHKLMWIPVYGGKTEEV-----------------------VLKEEQDSHVIEGLEP
GTEYEVSLLAVLDD--GSESEVVTAVGTTLDSFWT-EP----------------ATTIVP
TTSVTSVFQTGIRNLVVGDETTSSLRVK--WDISD-------------------SDVQQF
RVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDG-----EGVSV
SAPGKTLPS-------S-GPQNLRVSEEWYN-RLRITWDPPSSPVKGYRIVYKPVSVPGP
TLETFVGADINTILI------TNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNL
QAKHIEMTSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKI
SVYTKLQEI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------EGPS
VSIMEKTQSL------------PTRPPTFPPTI------PPAKEV---------------
CKAA--KADLVFMVDGSWSIGDENFNKIISFLYSTVGALHKIGTDGTQVAMVQFTDDPRT
EFKLNAYKTKETLLDAIKHISYKGGNT-KTGKAIKYVRDTLFTAESGTR--RGIPKVIVV
ITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKK
IE--DELITFV----C------------ETASAT---------------CPMVHK--DGI
DLAGFKMMEMFGLVEK---------DFSSVEGVSMEPGTFNVFPCYQLHKDALVSQPTRY
LHPEGLP-SDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNG-----------
-----------------GKTLTYFNYDQSGDFQTVTF-EGPEIRKIFYGSFHKLHIVVSE
TLV---------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
VVIDCKQVGEK--ATNASANITSDGVEVLGKM--VQSRGPGGNSAPF-------------
---------------------------------------------------------QLQ
MFDIVCSTSWANTDKCCELPGL------------------------------RDDESCPD
LP----------HSCSCSETNEVALGPAGPPGG---------------------------
----PGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQG------------------------
---------PPGPQGP--------------------------------------------
-------------------------SGLSIQG----------------------------
---------------------------MPGMP----GEKGEKGDTGL---PGPQGIPGGV
--------------GSPGRDGSPGQRGLP---------------GKDGSSGPPGPPGPIG
IPGTPGVPGITGSMGPQGALGPP------GVPGAKGERGERGDLQSQAMVRSVARQVCEQ
LIQSHMAR----------------------------YTAILNQIPSHSSSIRTVQGPPGE
PGRPGSPGAPGEQGPPGTPGF------------PGNAGVPGTPGERGLTGIK--GEKGNP
G--VGTQGPRGPP------------------GPAGPSGESRPGSPGPPGSPGPRGPPGHL
GVPGPQGPSG------------QPGYCDPS---SCSAYGVRGWMGIFL------------
-------------------------LDHPTLPSSPIT------------------SPPCS
PLVMDF-----------------------------------------------------
>gi|119591514|gb|EAW71108.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADV
KNGAA-ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLA---VGENDFHFALVQFNGN--
PHTEFLLNTYR--TKQEVLSHI-SNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP
QVIVVLTDGHSK--DGLAL-PSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNL
ENFTSLHDIVGNLVS--CVHSSVSPERAGD-----------------------TETLKDI
TAQDSADIIFLIDGSNNTGSV-NFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMF
SLDTYS-TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVL-VL
ISAGPSSDEIRYGVVALKQA---SVFSFGLGAQAASRAELQHIA--TDDNLVFTVPEFRS
FGDLQEKLLPYIVGVAQRHIVLKPPTI---VTQVIEVNKRDIVFLVDGSSALGL-ANFNA
IRDFIAKVIQRLEIGQDL----------IQVAVAQYADTVRPEFYFNTHPTKREVITAVR
KMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEI----SQPA
QELKRSSIMAFAIGNKGADQA-----------ELEEIAFDSSLVFIPAEFRAAPLQGMLP
GLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFP-----------YVRDFVMNLVN
SLDIGN-DNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYV
YANHFTEAGGSRIRE----HVP--QLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ
ANKAELEQI-------AFNPSLVYLMDDFSS-----------LPALPQQLIQP-------
-LTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPV-VRDFLYKIIDEL---NVKP
EGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVK
SAGSRIEDGVLQFLVLLVAGRSSDRV----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------DGPA
SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA
PAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLD-VGQDRVRVAVVQYSDRTRP
EFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV
LTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDF--AVAIPTFRQLGT
VQ--QVISERVTQLTR------------EELSRLQPVLQPLPSPGVGGKRDVVFL-IDGS
QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQR
LRPKGGR-QINVGNALEYVSRNIFKRPLG---SRIEEGVPQFLVLISSGKSDDEVDDPAV
ELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQ
KLLASTRYPPPV------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------R
EFRELPNIEER--IMNSFGPSAATPAPPGVDT--PPPSRPEKKKADIVFLLDGSINFRRD
SFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDF------------STKRQ
IIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQD
VSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMH
ETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGR
SPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSS
PDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFM
YDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQRGDRGPIGS---IGPKGIPGED
-----------GYRGYPGDEGGPGERGPP---------------GVNGTQGFQGCPGQRG
VKGSRGFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGR-RGDKGPRGEKGERGDV
GIRGD---------------------------------------PGNPGQDSQERGPKGE
TGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQ--GTRGA-
---QGPAGPAGPP--------------GLIGEQGISGPRGSGGAAGAPGERGRTGPLGRK
GEPGEPGPKGGIGNRGPRGETGDDGRDGVG---SEGRRGKKGERGFPG------------
-------------------------YPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIV
GQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPSTFHRAPGVPRLPNRTSLCFRHL
>gi|47211020|emb|CAF94689.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------C
QTEAV-ADMVFLVDGSWSIGRTNFRLVRVFLESLVKAFD---VDLDRTRIGLAQFSGE--
PRIEWHLNTHT--TKEAVMEAA-RNLPYKGGNTLTGLALTFILENSFSPESGSR--PGIP
KIGVLLTDGKSQ--DDVIP-PAQRLRDAGVEVFAIGVKNADEGELRAIASVSEDTHVYNV
ADFHLMADIVDVLTRTICERMETLHKQIAGLSSSHVTWPSAAGRVDSAPPAAAVSPPSDL
RVSEVTAHSFRVSWTQAPGQVEKYRVVYYPASG------GQPEEKVVPGTETSVLLTYLN
SLTEYQLAVFSVHHSSASQALRGGATTLALPTVDHLQLLHITHSSMLVRWTPAPGASGYM
VLYAPLSQEEPADEKEVKVD---GSPTE---------VELSHLT--P--ATEYTVTVYAM
FGE--EASDP--VSSQQTTLPLSPA--------------ANLRLSDVSHSSAQL--TWEP
ASSQVSGYRV-AYVQADGARTSQVSRGRVQMAGGRRSAGRRILRRVCCEQVDVGHVTS-W
LLSNLSPLTEYTVGVVALYDEGQADAATDSFTTKAVPEPLDFRSSQVSADGFRVSWEPPA
PDVLLYRLTWSPADGGPSQEVGSSFIAHLPAAPLRNVCPLCCRLCSRAAPPATSSRASGP
VCQYQVLLAATYGE--ELESQQLVLVQSTGAPLADPDPDADPDPDRSAFLVATFTTTVAT
TTSSTEAPDLALRELRLQEKTPFSIHLS--WQPPHT------------------STLQHY
RLSYSR-TGGAEETR----RLPADQTTVVLQPLLADSEYRFHVTPVYLHG-----DGPTS
TLMERTLPL-------S-APENLQVSEEWYN-RFRISWDAPPSPTLGYRIIYQPHSPPGA
ALETFVGEGVTSMLL------VNVLSGTEYIVTVTASYSSGASQPLSGRARTLFLGVSHL
LSYQVRTTSLCVQWQPQRHASTYRLLTESLPSGQKQEVRLSGATSRHCFNQLEPNTQYSV
SVHAQLADGSEGPAVTVTESTREFRATAWDRPQLPCRRRGPPDSPAPRRRPPAPPPKTVT
HGSARLLLSACLPPWSLTGKIGRAARADLAFLVDGSWSIGDDNFLKITRFLYSAVGALDR
IGPEGTQVAIVQFSDEPRTEVQLKSYRKKERLLEAISSISYKGGNTKTAPGAALETFVGE
GVTSMLLVNVLSGTEYIVTVTASYSSGASQPLSGRARTLFLGVSHLLSYQVRTTSLCVQW
QPQRHASTYRLLTESLPSGQKQEVRLSGATSRHCFNQLEPNTRYSVSVHAQLADGSEGPA
VTVTESTREFRATAWDRPPVAVPTPRPTRLPSTTPAPTSPTPKDV---------------
CRAA--RADLAFLVDGSWSIGDDNFLKITRFLYSAVGALDRIGPEGTQVAIVQFSDEPRT
EVQLKSYRKKERLLEAISSISYKGGNT-KTGRAIQHMKDSVFTEEGGAR--TAVPKVLVL
LTDGRSQDDVSKVSKELQKQGFVVFAIGFADADYGELVNVASKPSSTHVFFVDDLDAFKE
ME--EELVASV----C------------EAASAT---------------CPSAAM--SDS
ATPAFRMMELFGLVES---------RYSNVSGVSMVPGTFNSFPSFQLQADALLAQPTRL
LHPQGLP-SDYTITLLFRLLADAPQEPFALWEVLDRKREPLVGVVLDSQSPPPPTAGRGA
ANAGL---TRLLTFSDGGKTLTFFNSDQEGVVQAVTF-EGAHIQKLFYGSFHKLHVAVSQ
TSA---------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
VAIDCRTVAEK--SIRAAGNISTDGVEVLGRM--VRSTGTGDRSAPV-----------SA
ARSARDRRLLEGGGRSPEEWRREEGGLLQTGGSLVSSWVLVSSWASWVSSSCLCPSSRCR
LLDISCGTSWAGRDRCCELPGL------------------------------RKEADCPA
LP----------KACTCTQDSKGPPGPPGPPSRT--------------------------
----PSLSSPLSFLP-PSLKGPAGPVGETGVPGPQG------------------------
---------PQGPQGP--------------------------------------------
-------------------------SGRSIMG----------------------------
---------------------------PMGGP----GERGQKGEPGH---QGAQGLPGQA
--------------GAAGRDGPPGPRGLP---------------GKDGPQGRPGSPWNHG
APGA---PGTTGPTGKQGDLGPP------GLPGGKGEKGERGDVQSAVAVQAIARQVCEQ
LIQSECPRRVPVPQGQRSPGAGTLKTFPLPQVTWLATAPSSARFPVHQCPSELCRDPRES
PADLDLQGPRENRGQQEDLASLVRMAR------TGNRENEAHPEKRVKKDLKVLGSKAPE
DRQDHLVRPRTFPLRSIRALILDFLRPQAFRAREDPAARDLRADPGIQDLPGGPESPDPL
VLPDLPATVTRTRVWATTLEEVTDGAAVPP---VQLPANIFPNYGEVEED----------
-------------------------DPYRYYQPNYPAPRPVAPD-----------DPALT
PDRAN-GYRGARGAEEEGWRRRAEQTGAPSEERARRRD---------------------
>gi|73990553|ref|XP_853265.1|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MGES-------------GGYY--------NKL
RPGPEYADVVFLVDSSNHLGTKSFPFVKTFISKIINSLP---IEAHKYRVALAQYSDQ--
LHSEFQLGTFK--SRNPMLNHLKKNFGFVGGSLRIGQALREAHRTYFSRPDSGRDKKQFP
PILVVLASAESE--DDVEE-PSKALRGDGVRIISVGLQSASEQELKAMATGQFH---FNL
RSARDLGAFAPNMTQ--IIKEATQYREVAA------------------LDDVKVPLPMAC
QRDSLADLMFLVDES--VGTRQDLRNLQNFLRNITASMDMRYNCTRLGLMSYSDGAKTIS
LLNSST-SQYEFQEQIQKLSFQAGK-SHAGAAIEKMRLEAFSESSGSRRAQGVPQIA-VL
VTHRPSTDEVRDAALQLRLQ---DVTVFAMNIQGANDTQLEEIVSYPPRQMVSMLKSYAD
LEAYSNNFQKKLQNEIWSQISVRAGQMDLDRTGCIDTKEADIYFLIDGSTSINT-EGFEQ
IKQFMLAVTGMFSIGSDK----------VQAGAVQYSDKIRVEFYINASSNDMDLRKAIL
NIEQLQGNT-HTGKALDFMLSIIKKDRK--HRISEIPCHLIVLTDGKSQDEV----LKPA
ERLRDEQITIHAVGIGEADKI-----------QLQQIAGEEERVNFGQNFDS--LRNIKN
EVVHRICTEKGCED---MKADIMFLVDSSGSIGHDNFG-----------KMKTFMKNLLA
KIQIGP-DSTQIGVVQFSDINQEEFQLNKYFTQNETSDAIDRMSLINRGTL-TGSALTFV
-GQYFTPTKGARTKV--------KKFLILITDGEAQDPVRDPAKALRDKGVVIFSVGVYG
ANRTQLEEI-------SGDSSLVFQVENFDD-----------LKTVESKLVFR-------
---VCALHDCKNIKV------LDIVFVLDHSGSIGTQEQESMMNLTIHLVKKA---DVDS
DRVRVGALKYSDYPEVLFYLSGNKS--AVIEHLRRRRYTSGHTYTARALEH--ANIMFTE
EYGSRIQQNVKQMLIIITDGVSHDRDNL--------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------SDTA
SKLRNKGINIYAVGVGQANQLELETMAGNKSNTFHVDNFSNLKDIYLPLQEKMCTNAHEP
CDIQ--EADVIFFCDGSDMVSNSEFATMTTFVSDLIDNFN-IQNQRIKIGLAQFGSRFQK
IIELKNSLTIQELKTQIQTITKSKGFP-RIDLALKEV-KAMFDSSSGGRRNAGVPQTLVV
LTSGDPYYDVANEVKILRNLGICVLVWGIGNVHKEQFLPITGNSEK--IITLHNFNKLNN
VDVKKRMVREI----C------------QSCGKTNCFMDIVVGFDISTHLPGQPLFHDHP
RLRS----YLPDILE----------DITSIRRVSCGAGTEVQVNVAFKVNNDQ-EFPAKF
--------QIYQRAMFDSLLQVTVDGPTH-------------------------------
-------------------------LNAQFLLSLWDTFEAKSKSQGQVL-----------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------L
IFSDGLGGESEIMLENQSDRLRKAGLDALLVV--SLNTTAHDEFSSF-------------
------------------------------------------------------------
----------EFGKGFDYRTHL--------------------------------------
-------------TIGMRELGKKLSQYLGS------------------------------
----PGLKGTRGHRGED---GDPGRRGDIGPTGDSG------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------TAGCP----GEQGQKGEHGE---DGIDGLDGEE
-----------GIHGFPGAKGEKGDPGSQVTLSVYQRRRIWEGKAEGGPQGPWGSREILD
LKVPRELTDYKAHRENLEFLEIQ------GQWGKLDREEDRAQ-EDSLEIWGKRYSFTAL
HLEGDNS-----------------------------------LLIGLHFHLLTASGDVGD
PGVPGGPGPKGYRGLTLTVG---------RKGEEGSPGPPGPPGRRILELLC--GGPAS-
---SQPSAWHYWSTRQCDLIQFMRDHSREYLCVMEQGSRCIEKCPVYPTELVFALDQSNS
VSEQRFNEMRDIITSIVNDLNIRESNCPVGARVVVVSYDTGTSYLIRWSDYHSKKQLLQL
ISQI---------------------KYRPPTEAQDIGNAMRFVARNIFKRTYGGANVRKV
AVFFSSGQAASQSSIITATMEFNALDISPAVFAFSERIFLEAFEV--------------
>gi|45384490|ref|NP_990665.1|	Gallus gallus
------------------------------------------------------------
----------------------------------------------------MLCWNEVQ
SCFLLAFLAVAAYSV-----------------------------------SDAQGQVSPP
TRLRYNVVNPDSVQISWKAPKGQFSGYKLLVTPSSGGKTNQLILQNTATKAIIQGLIPDQ
NYALQIIAFSDDKESKPAQGQFRIKDIERRKETSKSKVKDPEKTNASKPTPEGNL--FTC
KTPAI-ADIVILVDGSWSIGRFNFRLVRLFLENLVSAFN---VGSEKTRVGLAQYSGD--
PRIEWHLNAYG--TKDAVLDAV-RNLPYKGGNTLTGLALTYILENSFKPEAGAR--PGVS
KIGILITDGKSQ--DDVIP-PAKNLRDAGIELFAIGVKNADINELKEIASEPDSTHVYNV
ADFNFMNSIVEGLTRTVCSRVEEQEKEIKG------------------TIAASLGAPTDL
VTSDITARGFRVSWTHSPGKVEKYRVVYYPTRG------GQPEEVVVDGSSSTAVLKNLM
SLTEYQIAVFAIYSNAASEGLRGTETTLALPMASDLKLYDVSHSSMRAKWNGVAGATGYM
ILYAPLTEGLAADEKEIKIG---EASTE---------LELDGLL--P--NTEYTVTVYAM
FGE--EASDP--LTGQETTLPLSPP--------------SNLKFSDVGHNSAKL--TWDP
ASKNVKGYRI-MYVKTDG---------------------------TETNEVEVGPVST-H
TLKSLTALTEYTVAIFSLYDEGQSEPLTGSFTTRKVPPPQHLEVDEASTDSFRVSWKPTS
SDIAFYRLAWIPLDGGESEEV-----------------------VLSGDADSYVIEGLLP
NTEYEVSLLAVFDD--ETESEVVAVLGATI-VGTTAIPTT---------VTTTTTTTATT
PKPTIAVFRTGVRNLVIDDETTSSLRVV--WDISD-------------------HNAQQF
RVTYLTAKGDRAEEAI---MVPGRQNTLLLQPLLPDTEYKVTITPIYADG-----EGVSV
SAPGKTLPL-------S-APRNLRVSDEWYN-RLRISWDAPPSPTMGYRIVYKSINVPGP
ALETFVGDDINTILI------LNLFSGTEYSVKVFASYSTGFSDALTGVAKTLYLGVTNL
DTYQVRMTSLCAQWQLHRHATAYRVVIESLVDGKKQEVNLGGGVPRHCFFELMPGTEYKI
SVHAQLQEI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------EGPA
VSIMETTLPF------------PTQPPTSPSTTLPPPTIPPAKEV---------------
CKAA--KADLVFLVDGSWSIGDDNFNKIISFLYSTVGALDKIGPDGTQVAIIQFSDDPRT
EFKLNAYKTKETLLEAIQQIAYKGGNT-KTGKAIKHAREVLFTGEAGMR--KGIPKVLVV
ITDGRSQDDVNKVSREMQLDGFSFFAIGVADADYSELVNIGSKPSERHVFFVDDFDAFTK
IE--DELITFV----C------------ETASAT---------------CPLVFK--DGD
KLAGFKMMEMFGLVEK---------EFSAIDGVSMEPGTFNVYPCYRLHKDALVSQPTKY
LHPEGLP-SDYTITFLFRILPDTPQEPFALWEILNEQYEPLVGVILDNG-----------
-----------------GKTLTFFNYDYKGDFQTVTF-EGPEIRKIFYGSFHKLHVVISK
TTA---------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
IIIDCKEAGEK--TINAAGNISSDGIEVLGRM--VRSRGPRDNSAPL-------------
---------------------------------------------------------QLQ
MFDIVCATSWANRDKCCELPGL------------------------------RDEENCPA
LP----------HACSCSEANKGPLGPPGPPGG---------------------------
----PGVRGAKGHRGDPGPKGPDGPRGEIGVPGPQG------------------------
---------PPGPQGP--------------------------------------------
-------------------------SGLSIQG----------------------------
---------------------------LPGPP----GEKGEKGDLGF---PGLQGVPGAS
--------------GSPGRDGAQGQRGLP---------------GKDGPTGPQGPPGPVG
IPGAPGVPGITGSQGPQGDVGAP------GAPGPKGERGERGDLQSQAMVRAVARQVCEQ
LIQGHMAR----------------------------YNSILNQIPSQSVSTRTIAGPPGE
PGRPGAPGPQGEQGSPGMQGF------------PGNPGQPGRPGERGLPGEK--GDRGNP
G--VGTQGPRGPP------------------GSTGPPGESRTGSPGPPGSPGPRGPAGHT
GPPGSQGPAG------------PPGYCDPS---SCAGYGMGGGYGEPTDQDIPVVQLPHN
SYQIYDPEDLYDGEQQPYVVHGSYPLPSPYSQSSYPSPHLA--------------QPEFT
PVREEMEAVELRSPGISRFRRKIAKRSIKTLEHKRENAKEPSQ----------------
>gi|114621480|ref|XP_519927.2|	Pan troglodytes
-----MKIFQ--RKMRYW------------------------------------------
------------------------------------------------------------
--LLPPFLAIVYFCT------------------------------------IVQGQVAPP
TRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQ
NYTVQIIAYNKDKESKPAQGQFRIKDLEKRKD-PKPRVKVVDRGNGSRPSSPEEVK-FVC
QTPAI-ADIVILVDGSWSIGRFNFRLVRLFLENLVTAFD---VGSEKTRIGLAQYSGD--
PRIEWHLNAFS--TKDEVIEAV-RNLPYKGGNTLTGLALNYIFENSFKPEAGSR--TGVS
KIGILITDGKSQ--DDIIP-PSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNV
AEFDLMHTVVESLTRTLCSRVEEQDREIKA------------------SAHAITGPPTEL
ITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRG------GKPDEVVVDGTVSSTVLKNLM
SLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYL
ILYAPLTEGLAGDEKEMKIG---ETHTD---------IELSGLL--P--NTEYTVTVYAM
FGE--EASDP--VTGQETTLALSPP--------------RNLRISNVGSNSARL--TWDP
TSRQINGYRI-VYNNADG---------------------------TEINEVEVDPITT-F
PLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLS
ADEGLHKLMWIPVYGGKTEEV-----------------------VLKEEQDSHVIEGLEP
GTEYEVSLLAVLDD--GSESEVVTAVGTTLDSFWT-EP----------------ATTIVP
TTSVTSVFQTGIRNLVVGDETTSSLRVK--WDISD-------------------SDVQQF
RVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDG-----EGVSV
SAPGKTLPS-------S-GPQNLRVSEEWYN-RLRITWDPPSSPVKGYRIVYKPVSVPGP
TLETFVGADINTILI------TNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNL
QAKHIEMTSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKI
SVYTKLQEI---------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------EGPS
VSIMEKTQSL------------PTRPPTFPPTI------PPAKEV---------------
CKAA--KADLVFMVDGSWSIGDENFNKIISFLYSTVGALHKIGTDGTQVAMVQFTDDPRT
EFKLNAYKTKETLLDAIKHISYKGGNT-KTGKAIKYVRDTLFTAESGTR--RGIPKVIVV
ITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKK
IE--DELITFV----C------------ETASAT---------------CPMVHK--DGI
DLAGFKMMEMFGLVEK---------DFSSVEGVSMEPGTFNVFPCYQLHKDALVSQPTRY
LHPEGLP-SDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNG-----------
-----------------GKTLTYFNYDQSGDFQTVTF-EGPEIRKIFYGSFHKLHIVVSE
TLV---------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------K
VVIDCKQVGEK--ATNASANITSDGVEVLGKM--VQSRGPGGNSAPF-------------
---------------------------------------------------------QLQ
MFDIVCSTSWANTDKCCELPGL------------------------------RDDESCPD
LP----------HSCSCSETNEVALGPAGPPGG---------------------------
----PGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQG------------------------
---------PPGPQGP--------------------------------------------
-------------------------SGLSIQG----------------------------
---------------------------MPGMP----GEKGEKGDTGL---PGPQGIPGGV
--------------GSPGRDGSPGQRGLP---------------GKDGSSGPPGPPGPIG
IPGTPGVPGITGSMGPQGALGPP------GVPGAKGERGERGDLQSQAMVRSVARQVCEQ
LIQSHMAR----------------------------YTAILNQIPSHSSSIRTVQGPPGE
PGRPGSPGAPGEQGPPGTPGF------------PGNAGVPGTPGERGLTGIK--GEKGNP
G--VGTQGPRGPP------------------GPAGPSGESRPGSPGPPGSPGPRGPPGHL
GVPGPQGPSG------------QPGYCDPS---SCSAYGVR-------------------
-------------------------APHPD-------------------------QPEFT
PVQDELEAMELWGPGV-------------------------------------------
>gi|119890597|ref|XP_001256059.	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------MRKHRHLPLVAILCLFFSGFSFTRGQQQ-PDV
KNGAA-ADIIFLVDSSWSIGKEHFQLVREFLYDVIESLA---VGDNDFRFALVQFNGN--
PHTEFLFNTYR--SKQEVLSHV-SNMSYIGGSNQTGKGLAYVMQNHLTEAAGSRASDGVP
QVIVVLTHGHSE--DGLAL-PSAELKSADVNVFAIGVEDADEAALKEIASEPLNMHVFNL
ENYTSLHDIVGNLVA--CVRSSMAPERAGG-----------------------TEIPKDI
TAQDSADIIFLIDGSNNTGSV-NFAVILDFLVNLLERLSIGTQQIRVGVVQYSDEPRTMF
SLNSYS-TKAQVLDAVKALGFIGGELANVGLALDFVVENHFTRAGGSRAEEGVPQVL-VL
ISAGPSSDEIRDGVIALKQA---SVFSFGLGAQAASKAELQHIA--TNDNLVFTVPEFRS
LGDVQEQLLPYIVGVAQRHIVLQPPTI---VTQVIEVNKRDIVFLVDGSSKLGL-TNFNA
IRDFIAKVIQRLEIRQDL----------IQVAVAQYADTVRPEFYFNTYPSKREVINAVR
KMKALDGSALYTGSALDFVRNNLFTEAAGYRAAEGVPKLLVLVTGGKSLDAV----SQPA
QELKRSGILAFAVGNKVADQA-----------ELEEIAFDSSLVFTATEFRPAPLQGVLP
GLLGPLRTLTGTTEVRVNKRDIIFLLDGSSNVGETNFP-----------YVRDFVMNLVN
SLDVGS-DHIRVGLVQFSDTPVTEFSLNTYPTKSELLAHLRQMQLQGGSVLNTGAALSYV
HANHFTEAGGSRIQD----HVP--QLLLLLTAGQSEDSYLQAANALARAGILTFCVGTSQ
ADRAELEEI-------AFNPGLVYLMDDFSS-----------LPALPQQLIQP-------
-LTTYVSGGVEEVPLAQPESKRDILFLFDGSANLMGQFTA-ARDFLYKVIDEL---DVKP
EGTRVAVAQFSDDVKVESRFDQHQNKPEILNLVKRMKLKTGKALNLGYALDYAQRYIFVK
SAGSRIEDGVLQFLVLLVAGKSSDRV----------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------DTPA
LNLKQSGVVPFILQAKNADPAELELIVPSPAFILVAESLPKIGDLQPQIVNLLKSVQNGA
PAPVSVEKDVVFLIDGSEGV-RSGFPLLKEFVQRVVESLD-VGPDRVRVAVVQYSDRTRP
EFYLNSYMDQQSVVGAIRGLTLLGGPAPNTGAALEFVLRNILVGSAGSRIAEGVPQLLIV
LTADRSGDDVRGPSVVLRRGGAVPIGIGIGNADITEMQTLSFVPDF--AVVIPTFRQLGT
IQ--QVISERVTQLSR------------EELSRLQASVTPLTTPVVSSKRDVVFL-IDGS
QSAGPEFQYIRTLIERLVDYLDVGFDTTRVAVIQFSDDPRVEFLLNVHSSKDEVQNAVRR
LRPKGGR-QVNVGGALEYVARNIFKRPLG---SRIEEGVPQFLVLISSGKSDDEVEDSAI
ELKQFGVAPLTIARNVDQEELVKISLSPEYVFSVNTFRELPSLEQKLLTPLTTLTAGQIQ
QLLASTRYPPP-------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------A
VESDAADIVF---LIDSSDGVKPDGIAHIRDFVIRIVRRLNVGPNKV-------------
-----------------------RIGVLQFSNDVFPEFQLKTY------------KSQAS
VLDAIRRLRFKGGSPLNTGKALEFVARNYFVKSAGSRIEDGVPQHLVLFLGGKSQDDISR
YSQVIKSAGIASLGVGDRNIDRTELQTITSDPRL--------------------------
------VFTVREFRDLPSI--------EERMVNSFG------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------SSGVT------------------PAPPGVDTPS
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------PSRP------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------
