>gi|91085811|ref|XP_974701.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MMEEMFTELPVPLL--STAAIIR-------------HHTRYQ-PYQRLHQPQ--HFHTP
VQELHA------------------------------------------------------
----------------LQQPDHGTTHISCLYPEILAIIFSYLE-VRDKG-RVAQVCTAWR
D----AAYNK---SVWRGVEAKLHLRRANPSLFA------SLVKRGIK------------
-------------------------------------RVQVLSLR-------KSLRDVIQ
GI-PNLESLNLRG-CY--------------------NVGDVGISHAFVADSPTLTELDLS
LCKQVTDT---------SLTRIAQ-HLKNLEVLELGGCSNV-------------------
------------------------TNSGLMLIAWGL------------------------
--------------------------KKLKRLNLRSCWHVGDQGIQHL-ASG--------
-------------------NPSLEHLGLQDCQKLSDEALKHATGL-TSLISINLSFCVS-
-ITDSGLKHLAK------------------------MTNLRELNLRSCDNISDTGMAFLA
EG-GS-----RISSLDVSFCDKIGDQALVHISQGLFNLRNLLMSACQ-LSDEGLAKIAN-
-------SLHDLETLNIGQCSRVTDKGLTTIAESL---LRLKCID-LYG-----------
-CTRITTV---------------GLERIM--------------------KLPQLSVLNLG
L------------------------------------WHVR-------------------
--------------------------
>gi|149577087|ref|XP_001521021.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
-MPFWFRVRSQSAARVARLPSCITRTTGRARARGPPRRPARPQRCHAPPQRGLAAPRPGP
RGQARDQRRIPFCLL--SMGTPWAGSWGEGEGHQ---KIPPWM-LSGRRPRSG--PWGEG
EGRR---------ETPGRMLSMGRPRAGSWGEGEGRQKIPVLGAKHEKTLIRVLGRGRGA
STDPTLGAEHEKTLAWVFSSSDEALINKKLPKELLLRIFSFLD-IVTLC-RCAQISKAWN
V----LALDG---SNWQRIDLFNFQTDIEGRVVE------NISKRCGG------------
-------------------------------------FLRQLSLRGCLGVGDSSLKTFAQ
NC-RNIEHLNLNG-CT--------------------KITDSTC-YSLSKFCSKLKHLDLT
SCVSITNS---------SLKGLSE-GCRNLEHLNLSWCDQV-------------------
------------------------TKEGIEALVKGC------------------------
--------------------------SGLKALFLRGCTQLEDEALKHI-QNH--------
-------------------CHELVILNLQSCTQISDEGIVKICRGCHRLQALCVSGCSN-
-LTDASLTALGL-----------------------NCPSLKILEAARCSHLTDAGFTLLA
RN-CH-----ELEKMDLEECILITDSTLIQLSVHCPRLQALSLSHCELITDDGILHLSSS
-----PCGQERLQVLELDNCLLITDVTLEHLE-SC---RSLERIE-LYD-----------
-CQQVTRA---------------GIKRIRAHL------PDVKVHAYFAPVTPPPSVGGSG
Q------------------------------------RLCRCCVIL--------------
--------------------------
>gi|119913353|ref|XP_597007.3|	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------MEVENNDTLRE
RVEGKGSSSISSDVS--SSTDHTPTQA----------QKNVAT-SEDSDLSMR--TLSTP
SPAL---------ICPP--------NLPGFQNGRGSST--------SSSSITGETVAMVH
SPPPTRLTHPLIRL--ASRPQKEQASIERLPDHAMVQVFSFLP-TNQLC-RCARVCRRWY
N----LAWDP---RLWRTIRLTGETINVDRALKV------LTRRLCQDTPN---------
----------------------------------VCLMLETVSVSGCRRLTDRGLYTIAQ
CC-PELRRLEVSG-CY--------------------NISNEAV-FDVVSLCPNLEHLDVS
GCSKVTCISLTREASI-KLSPLHG-KQISIRYLDMTDCFVL-------------------
------------------------EDEGLHTIAAHC------------------------
--------------------------TQLTHLYLRRCVRLTDEGLRYL-MIY--------
-------------------CTSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGR-
-VTDVGIRYVAK-----------------------YCGKLRYLNARGCEGITDHGLEYLA
KN-CA-----KLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAA-
---------------------------------NC---FDLQMLN-VQD-----------
-C-EVSVE---------------ALRFVK-------------------------------
-------------------------------------RHCKRCVIEHTNPAFF-------
--------------------------
>gi|115920953|ref|XP_785847.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
--------MFMKLSLIGSLMWNNRDDQRCANPSQKARPLTNGWMDGGIDQVLFKTNIPRL
RGNSKIYYLQGTWSL--VNYHLLTDRGALALGYDSLKLENIPN-GSITKKLPQ--PPTTP
TSDIQTPESTAKSSIASNRSKSPTSSAELSKTNSSTRS--------ASESNYNGNNNAEI
AYEDDIGQGQEDAASSRTLDVQRPSPFDRLTDSIITNMFSYLS-TKQLC-RCSCVSRRWH
R----LAWQP---TLWTTIQLSGRRLDVNFALKV------LVKRLSRETPY---------
----------------------------------LCLSVERLFLNGCHRLSDKALELVAH
RC-PELLHVELMG-CH--------------------QISNAAI-FQIVSRCPNLDYLDIS
GCKQVDCMNLPVEPAYSDPKDFLK-QRINLRHLDMSDCSLL-------------------
------------------------DDNGLRTIATNC------------------------
--------------------------PTLVNLYLRRCVGVTDIGVQYV-TTQ--------
-------------------CLMLKEVSLSDCPRVTDCAMRELAKLEYHLRYLSVAKCEL-
-ITDMGVYAIAK-----------------------HCYKLRYLNVRGCVLVSDKSLEALS
RG-CP-----RLRSLDVGKCPLITDHGLVSIATNCQSLRKLSLKGCLHVTDQVIEVLAQ-
---------------------------------VC---PDLQQLN-IQD-----------
-CDEVSRE---------------AYRLLK-------------------------------
-------------------------------------RCCRKCIIEHTNPAFY-------
--------------------------
>gi|156538275|ref|XP_001603165.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
MKYGFIRPLAPLDAL--MANNRDADGI----------SMSIWR-HQ--------------
------------------------------------------------------------
----------------FHSDNEKAQINKKLPKELLLRILSYLD-VVSLC-RCAQVSKAWN
V----LALDG---SNWQRIDLFDFQRDVEGPVIE------NISRRCGG------------
-------------------------------------FLRQLSLRGCQSIGNVSMKTLAQ
SC-PNIEELNLSQ-CK--------------------KISDTTC-AALSNHCPKLQRLNLD
SCPEITDL---------SLKDLSD-GCRLLTHINLSWCELL-------------------
------------------------TDNGVEALARGC------------------------
--------------------------PELRSFLSKGCRQLTDRAVKCL-ARF--------
-------------------CPKLEVINLHECRNITDEAVKELSERCPRLHYVCISNCPN-
-LTDSSLSTLAQ-----------------------HCPLLSVLECVACAHFTDAGFQALA
RN-CR-----LLEKMDLEECVLITDATLIHLAMGCPRLEKLSLSHCELITDEGIRQLALS
-----PCAAEHLAVLELDNCPLITDASLDHLLQAC---HNLERIE-LYD-----------
-CQLITRA---------------GIRRLRTHL------PNIKVHAYFAPVSPPPSAGASR
Q------------------------------------RYCRCCVIL--------------
--------------------------
>gi|126321061|ref|XP_001373248.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MPRVRGQSVVYGKYQDGQRHSMARY
KEASKGSSSISSDVS--SSTDHTPTKA----------QKNAAT-SEDSDLSMR--TLSTP
SPAL---------ICPQ--------NLQGFQNGRGSST--------SSSSITGETVAMVH
SPPPTRLTHPLIRL--ASKQQKEQAHIDRLPDHSMVQIFSFLP-TNQLC-RCARVCRRWY
N----LAWDP---RLWRTIRLTGETINVDRALKV------LTRRLCQDTPN---------
----------------------------------VCLMLETVTVSGCRRLTDRGLYTIAQ
CC-PELRRLEVSG-CY--------------------NISNEAV-FDVVSLCPNLEHLDVS
GCSKVTCISLTREASI-KLSPLHG-KQISIRYLDMTDCFVL-------------------
------------------------EDEGLHTIAAHC------------------------
--------------------------TQLTHLYLRRCVRITDEGLRFL-MIY--------
-------------------CSSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGR-
-VTDVGIRYVAK-----------------------YCSKLRYLNARGCEGITDHGVEYLA
KN-CT-----KLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAA-
---------------------------------NC---FDLQMLN-VQD-----------
-C-EVSVE---------------ALRFVK-------------------------------
-------------------------------------RHCKRCIIEHTNPAFF-------
--------------------------
>gi|73954399|ref|XP_546380.2|	Canis familiaris
------------------------------------------MCADERLRKSDHVDHLRS
CCWRWLQTASTSLRAARIVSLVGGVWGTARPRPWAQETVVQEAVVREAMGPEAVSPEAVG
LGGCGLGGHGPGSRGLGGCGSGGRGPRGGLALATSSHSLLFRCLALNVTSAAFCWTCRAP
GLVGRAGAGAGAWRLDGCSRGHLPPGFAGPQGSRRRCPSTSLL-GTDSDLSMR--TLSTP
SPAL---------SCAP-------GAPGGCQNGRGSST--------SSSSVTGETVALVH
APPPPRLTHPLIRL--AARPQREQARVERLPDACLVRVFSFLR-TDQLC-RCARVCRRWY
N----VAWDP---RLWRAIRLAGAGLHADRALRV------LTRRLCQDTPN---------
----------------------------------VCLLLETVAVSGCRRLTDRGLYTLAQ
CC-PELRRLEVAG-CH--------------------NISNEAV-FDVVSLCPNLEHLDVS
GCSKVTCISLTREASI-QLSPLHG-KQISIRYLDMTDCFAL-------------------
------------------------EDEGLHTIAAHC------------------------
--------------------------TRLTHLYLRRCARLTDEGLRYL-VIY--------
-------------------CSSLRELSVSDCRCISDFGLREIAKLEARLRYLSIAHCGR-
-VTDVGIRYVAR-----------------------YCGKLRYLNARGCEGITDHGVEYLA
KH-CA-----RLKSLDIGKCPLVSDSGLECLALNCFNLKRLSLKSCESITGRGLQIVAA-
---------------------------------NC---FDLQMLN-VQD-----------
-C-DVSVE---------------ALRFVK-------------------------------
-------------------------------------RHCRRCVIEHSNPAFC-------
--------------------------
>gi|24646754|ref|NP_650335.1|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
-----MGNSLITSGKPSQRREKRLFERLSCSYAQTPNRMELNLNPLLAIARSIAAPPTPP
PTPEKLDSDKDKEGS--SKAAIELLPN------EMWLEIMSYL-SYNDLLQLR--MVSWR
CRDLVHRRRFMEKGKVIVTQHNLEAIHKHAKGGNCYLS--------FERIELRNLRQCRQ
LENFLRLVGHEVKHLQVRHAPVFRNLDGKLPNLKVLTIATTMSMDDQHLAAMDDLDMKQF
SHLVGFECDGVSLDAVLKMRMLLQLRRTENKVQL------RHLQFEFRRNNEN-------
------------------------ALLDVLQDHAETLVCVNLFFSCSPGIDTREWCRAFE
NM-HNLRTLKLSGNCH--------------------LVLLEAVLRAVPESAP-IRQLDLT
GMLSLTNE---------LLLYVAGKWQSTLKVLDLMFCVQL-------------------
------------------------NANCIDALRQLS------------------------
--------------------------GRLEALTMAYCRELTGTGLLQG-LAGDI------
-------------------NYSLQELHLEETIFLDESSMCQLLERLPNLRRLSLDNCRQA
-VTDRTMATICQ-----------------------YQTRLRNLNIEYCMKITDQGLMGYG
DTPYPISRLRGLKELNLRGCRNVTDSSLM-VGLKLPELRALSLGYCNRLTSEGFEALTQ-
-------NCPSLEALCVSSCMAVDDETVLNIVSNL---KRLRVLN-LSN-----------
-CTKLTLQ---------------SIHHILAHGHNLV--QLIACSIDGMDHEQAQRILESQ
R------------------------------------PQMKQVLL---------------
--------------------------
>gi|48096980|ref|XP_393659.1|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------MEESQLLMTELPA
LTPSRGTTLLHRSRH--YYQLHQPHLA----AIPTSQSQGILY-NSSNAPHYT--SGTTG
LPAY------------------------------------------AQGLSSRQQPQVI-
----------------ARGTVTPSTHISCLYPEILALIFSYLE-VRDKG-RAAQVCTAWR
D----AAYYR---SVWRGVEARLHLRKQAPALFA------SLVRRGVK------------
-------------------------------------RVQVLSLR-------RGLGDVLK
GV-PNLEALNLSG-CY--------------------NITDAGLINAFCQEYTTLTELNLS
LCKQVSDI---------SLGRIVQ-YLKNLEHLELGGCCNI-------------------
------------------------TNGGLLCIAWNL------------------------
--------------------------KKLKRLDLRSCWQVSDLGIAHLAGVNREAAGG--
-------------------NLALEHLSLQDCQRLSDEALRHVSIGLTTLKSINLSFCVC-
-ITDSGLKHLAK------------------------MSSLRELNLRSCDNVSDIGMAYLA
EG-GS-----RISSLDVSFCDKIGDQALVHISQGLFNLKLLSLSACQ-ISDEGICKIAK-
-------TLHDLETLNIGQCSRLTDKGLYTIAESM---KHLKCID-LYG-----------
-CTRISTN---------------GLERIM--------------------KLPQLSTLNLG
L------------------------------------WHVR-------------------
--------------------------
>gi|157015209|gb|EAA12920.4|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------KSCIIPDDEISRKLPKEILLRILSYLD-VTSLC-RCGQVSRYWN
I----LALDG---SNWQKIDLFDFQRDIEGPVIE------NISQRCGG------------
-------------------------------------FLKYLRLRGCQSVGSHSIRTLAN
YC-HNIEHLDLSE-CK--------------------KISDVAI-QQLSKNCAKLTAINLE
SCSQISDS---------SLKALSD-GCPNLSEINVSWCNLI-------------------
------------------------TENGVEALARGC------------------------
--------------------------NKIKKFSSKGCKQVNDRAVIAL-ALY--------
-------------------CPGIEVLNLHSCDSITDASISKIAEKCCNLKQLCVSKCTE-
-LTDQSLTALAM-----------------------NNQYLNTLEVAGCAQFTDSGFIALA
KN-CK-----YLERMDLEECSLITDATLQNLALGCPSLEKLTLSHCELITDEGIRQLAGG
-----GCAAESLSVLELDNCPLITDATLEHLI-SC---HNLQRIE-LYD-----------
-CQLISRN---------------AIRRLRNHL------PNIKVHAYFAPVTPPPTINGPR
P------------------------------------RYCRCCEIL--------------
--------------------------
>gi|34785062|gb|AAH20572.2|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------FFYLS-LKDVI-ICGQVNHAWM
L----MTQLN---SLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNFRGCL-------
------------------------LRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISE
GC-PGVLCLNLSN-T---------------------TITNRTM-RLLPRHFHNLQNLSLA
YCRRFTDKGL-------QYLNLGN-GCHKLIYLDLSGCTQI-----------------SV
QGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSA
CKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSL-SPLKQLTVLNL
ANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEH-
-LTAQGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFC
KS-SL-----ILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSA-
-------KCHYLHILDISGCVLLTDQILEDLQIGC---KQLRILK-MQY-----------
-CTNISKK---------------AAQRMSSKVQQQEYNTNDPPRWFGYDREGNPVTELDN
I------------------------------------TSSKGALELTVKKSTYSSEDQAA
--------------------------
>gi|148671256|gb|EDL03203.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------SQEFEDCLKL
TWMNFLDWMTSWSTL--LRLRHLFYMQ----------RQRIIL-AKWKERARH--KSKTR
EDDL------------------------------------------ISKHELQLKKWKFK
LGKPISLEGSLSDI--AVENRRIAFDISVLPEQAILQIFLYLT-FKDMM-ACSRVNRSWM
A----MIQRG---SLWNSIDFSTVKNIADKCVVT-TLQKWRLNVLRLNFRGCD-------
------------------------FRTKTLKAVSHCKNLQELNVSDCQSFTDESMRHISE
GC-PGVLYLNLSN-T---------------------TITNRTM-RLLPRYFHNLQNLSLA
YCRKFTDKGL-------QYLNLGN-GCHKLIYLDLSGCTQVLVEKCPRISSVVLIGSPHI
SDSAFKALSSCDLKKIRFEGNKRISDACFKSIDRNY------------------------
--------------------------PGINHIYMVDCKGLTDSSLKSL-SLLKQLTVLNL
TNCIRIGDIGLKHFFDGPASIRLRELNLTNCSLLGDSSVIRLSERCPNLHYLNLRNCEH-
-LTDLAIEYIASMLSLISVDLSGTLISNEGMTILSRHRKLREVSVSDCVNITDFGIRAYC
KT-SL-----LLEHLDVSYCSQLTDDIIKTIAIFCTRITSLNIAGCPKITDAGMEILSA-
-------RCHYLHILDISGCIQLTDQIIQDLQIGC---KQLRILK-MQF-----------
-CKSISPA---------------AAQKMSSVVQHQEYNSDNPPHWFGYDSEGNPLDKIHS
R------------------------------------VQLRTYSKLIVKEPFSIDEEDPD
SKHQ----------------------
>gi|114601101|ref|XP_001137158.	Pan troglodytes
-------------------------------MYPPSGTPAPEEASLLQLVPPPAPSPQAA
SPDPSQGAPSAGGAPEPGLLLPRALHALLHRAQSRRARPRRPRGGAAALAAAAGRGLRCS
LLLSAPGAALRGPGRRGLRRCCPPLPAILGRRRRRRCRLGFVARLLLQRVGAGCGRRLGA
AGPKSLPGQLGAGAL--PGAARRRAAL------PGADTVTGRA-PYAPRNGVQ--AEGGR
GPRLHPLQAPPQPLCPPPSSPTSEGAPTEAGGDAVRAGG-------TAPSSAQQQHECGD
ADCREPPENPCDC---HREPPPETPDINQLPPSILLKIFSNLS-LDERCLSASLVCKYWR
D----LCLDF---QFWKQLDLSSRQQ-VTDELLE------KIASRSQ-------------
-------------------------------------NIIEINISDCRSMSDNGVCVLAF
KC-PGLLRYTAYR-CK--------------------QLSDTSI-IAVASHCPLLQKVHVG
NQDKLTDE---------GLKQLGS-KCRELKDIHFGQCYKI-------------------
------------------------SDEGMIVIAKGC------------------------
--------------------------LKLQRIYMQENKLVTDQSVKAF-AEH--------
-------------------CPELQYVGFMGCS-VTSKGVIHLTKL-RNLSSLDLRHITE-
-LDNETVMEIVK-----------------------RCKNLSSLNLCLNWIINDRCVEVIA
KE-GQ-----NLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQ-
-------SSKSLRYLGLMRCDKVNEVTVEQLVQQY---PHITFSTVLQD-----------
-CKRTLER---------------AYQM---------------------GWTPNMSAASS-
------------------------------------------------------------
--------------------------
>gi|121921406|sp|Q15I80|GRRA_EM	Emericella nidulans
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MARS
RQPTRFSSEAPSESS--SSTSPERAAD------D---DTDFFT-LQANDSQSS--I-GAG
NPRD---------SHI--------------------------------------------
----------------QNDPETVLPPIAYLPPEILISIFSKLSSPRDLL-SCLLVCRIWA
LNCVGLLWHRPSCNNWDNLKKIAAAVGEEDSFFL---YSSLIKRLNLSALTED-------
------------------------VSDGTVVPFSQCNRIERLTLTNCRKLTDIGVSDLVV
GS-RHLQALDVSE-LR--------------------SLTDHTL-FKVAENCNRLQGLNIT
GCVKVTDD---------SLIAVSQ-NCRLLKRLKLNGVSQV-------------------
------------------------TDKAILSFAQNC------------------------
--------------------------PSILEIDLQECKLVTNQSVTALMTTLQNLRELRL
AHCTEIDDSAFLDLPRHIQMTSLRILDLTACENIRDEAVERIVSSAPRLRNLVLAKCKF-
-ITDRAVWAICK-----------------------LGKNLHYVHLGHCSNINDSAVIQLV
KS-CN-----RIRYIDLACCSRLTDRSVQQLAT-LPKLRRIGLVKCQLITDASILALARP
-AQDHSVPCSSLERVHLSYCVNLTMVGIHALLNSC---PRLTHLS-LTGVAAFLREELTV
FCREAPPEFTRQQREVFCVFSGEGVNRLRNHLNREAAPQRDANEATMYDDEEELDEDEGQ
V------------------------------------TGLMHAAAINDDD--YINITPPH
A-------------------------
>gi|157116098|ref|XP_001652767.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------------MTS
SSK----------YCLM-------------------------------------------
----------------KTYIIPEDEISKKLPKEILLRILSYLD-VTSLC-RCGQVSRYWN
I----LALDG---SNWQKINLFDFQRDIEGTVIE------NISLRCGG------------
-------------------------------------FLKYLCLRGCQSVGSQSIRTLAQ
HC-HNIEHLDLAE-CK--------------------KITDVAI-QPLSKNCSKLTAINLE
SCSEISDC---------SLKALSD-GCPNLTEINVSWCNLI-------------------
------------------------TENGVEAIARGC------------------------
--------------------------NKVKKFSSKGCKQVNDRAVIAL-ALF--------
-------------------CPNIEVLNLHSCETITDASVSKIAEKCINLRQLCVSKCCE-
-LTDHTLIALAT-----------------------YNHYLNTLEVAGCTQFTDSGFIALA
KN-CK-----YLERMDLEECSQITDATLSNLAVGCPSLEKLTLSHCELITDEGIRQLAAG
-----GCAAESLSVLELDNCPLITDATLEHLI-SC---HNLQRIE-LYD-----------
-CQLISRN---------------AIRRLRNHL------PNIKVHAYFAPVTPPPTSNGPR
P------------------------------------RYCRCCEIL--------------
--------------------------
>gi|148227558|ref|NP_001087065.	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------M
RRDMNGVTKSRFE-----------------------------------------------
------------------------------------------------------------
----------------MFSNNDEALINKKLPKELLLRIFSFLD-VVTLC-RCAQVSRAWN
V----LALDG---SNWQRIDLFDFQRDIEGRVVE------NISKRCGG------------
-------------------------------------FLRKLSLRGCLGVGDNALRTFAQ
NC-RNIEVLNLNG-CT--------------------KITDTTS-TSLSKFCSKLRQLDLA
SCTSITNL---------SLKAISE-GCPQLEQLNISWCDQI-------------------
------------------------SKDGVQALVKGC------------------------
--------------------------GGLRLLSLKGCTQLEDEALKFI-GSH--------
-------------------CPELVTLNLQACSQITDDGLITICRGCHKLQSLCASGCAN-
-ITDSILNALGQ-----------------------NCPRLRILEVARCSQLTDLGFTTLA
KN-CH-----ELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNG
-----ACAHDRLEVIELDNCPLITDASLEHLK-SC---QSLERIE-LYD-----------
-CQQISRA---------------GIKRLRTHL------PNIKVHAYFAPVTPPPSVGGSR
Q------------------------------------RFCRCCAIL--------------
--------------------------
>gi|121702599|ref|XP_001269564.	Aspergillus clavatus
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MPRS
RQPARFSSEAPSDSS--SSTSPDRTVD------D---DTDFFM-AQANDSQSS--V-GVG
HFRE---------SHDP-------------------------------------------
----------------NSNNNMVLPPIGHLPPEILIAIFARLSSTTDLL-SCMLVCRGWA
ANCVGILWHRPSCNNWDNLKRVTASVGKSDSLFA---YSELIKRLNLSALT-D-------
------------------------VNDGTIVPFAQCKRIERLTLTSCSKLTDNGVSDLVE
GN-RHLQALDVSD-LR--------------------SLTDHTL-YTVARNCPRLQGLNVT
GCLKVTDD---------SLIVVSR-NCRQIKRLKLNGVGQV-------------------
------------------------TDRSIKSFAENC------------------------
--------------------------PAILEIDLHDCNLVTNDSVTSLMSTLRNLRELRL
AHCTEISDSAFLDLPESLTLDSLRILDLTACENVQDDAVERIVSAAPRLRNLVLAKCKF-
-ITDRAVQAICK-----------------------LGKNLHYVHLGHCSNITDPAVIQLV
KS-CN-----RIRYIDLACCNRLTDASVQQLAT-LPKLRRIGLVKCTLITDESILALARP
KVTPHPLGTSSLERVHLSYCVRLTMPGIHALLNNC---PRLTHLS-LTGVVAFLDPQITR
FCREAPPEFTQQQREVFCVFSGEGVNRLRDYLNHRSSSGREMSEATMYDDDEELDEDEGQ
V------------------------------------TGLMHATVISDED--YIDIGHAP
G-------------------------
>gi|149732983|ref|XP_001499844.	Equus caballus
MCRAPSSGNRGPAARGGALPLPKSGLRGEAARAPSYCSLGAPRTSGRRALPGEPAGAEGR
PEELWRRGIRARARLSATAGESGRADGDPAAAARAAADPSPTRNNRGCQEGTERPPPTGV
RGPPLAGDRPRSVGYAQLTGPVGRAFPLAERAGGAPQLWSVPGDGGHDGGRMGANNGKQY
GSEGKGSSSISSDVS--SSTDHTPTQA----------QKNVAT-SEDSDLSMR--TLSTP
SPAL---------ICPP--------NLPGFQNGKGSST--------SSSSITGETVAMVH
SPPPTRLTHPLIRL--ASRPQKEQASIERLPDHSMVQIFSFLP-TNQLC-RCARVCRRWY
N----LAWDP---RLWRTIRLTGETINVDRALKV------LTRRLCQDTPN---------
----------------------------------VCLMLETVTVSGCRRLTDRGLYTIAQ
CC-PELRRLEVSG-CY--------------------NISNEAV-FDVVSLCPNLEHLDVS
GCSKVTCISLTREASI-KLSPLHG-KQISIRYLDMTDCFVL-------------------
------------------------EDEGLHTIAAHC------------------------
--------------------------TQLTHLYLRRCVRLTDEGLRYL-MIY--------
-------------------CTSIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGR-
-VTDVGIRYVAK-----------------------YCSKLRYLNARGCEGITDHGVEYLA
KN-CT-----KLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAA-
---------------------------------NC---FDLQMLN-VQD-----------
-C-EVSVE---------------ALRFVK-------------------------------
-------------------------------------RHCKRCVIEHTNPAFF-------
--------------------------
>gi|149038007|gb|EDL92367.1|	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------MADSLPL
EMLTYILSFLPLSDQ--KEASLVSRAWYYAAQNALRETNVRYNIPVSSASLSA--IKSLG
RRGI---------SCI--------------------------------------------
----------------SLTNLDGSPASHQVLQSVAYHLGPHLQ-SLCLG-GGSPTEASFL
A----LILGC---PVLRTLDLSGCNSLFTSGTLL------AQPETAQCVRK---------
----------------------------------ALSGLRDLNLAGLRDLTDLSFNHLSS
CF-PSLERLSLAY-CHLTFELGSTWGSTSPQASSPSQLSFHNLLQFIKERAGTLRALDLS
GTGLPPE----------ALQALGQVTGLKLEELNLNSCKDL-------------------
------------------------SSEAVATLCRQQ------------------------
--------------------------PGLTSLDLSGCSELTDRALLAV-SRG--------
-------------------LHHLRHLSLKKLQRLTDAGCIALGAL-HELQSLDMAECCL-
-VSGRELAQVLG-------------------SVRRAPPALTSLRLAYCSSLKDASVLSMI
PALGP-----SLKVLDLSSCVALTNQTMQAICTYLIHLSVLRLAWCKELQDWGLLGLKEP
--SDEPVLNPQLHQEVENQAPDHQEPSSEPQGSSLLMLQALQELD-LTA-----------
-CSKLTDA------SLAKVLQFPQLRQLSLSLLPAFTDMGLVAVARGCPSLERLTLSHCS
HLSDEGWVQAARLWPRLQHLNLSSCSQVTEQTLDTIGQACKQLRVLDVAMCPGINMAAVK
HFQAQLPQVTCIQSRFVGGADLTLTL
>gi|83764797|dbj|BAE54941.1|	Aspergillus oryzae
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MPRS
RQPARFSSEAPSESS--SSTSPDRNVD------D---DTDFFT-AQANDSQSS--VGGIA
TSRD---------VH---------------------------------------------
----------------AQNEHYVLPPIGRLPPELLIAIFAKLSSPADML-SCMLVCRGWA
ANCVGILWHRPSCSNWVNMKSITMTVGKEDSFFS---YSDLIKRLNLSALMEE-------
------------------------VSDGTVVPFAQCNRIERLTLTNCSKLTDKGVSDLVE
GN-RHLQALDVSD-LR--------------------SLTDHTL-YTVARNCPRLQGLNIT
NCVKVSDD---------SLIVVSE-NCRHIKRLKLNGVIQV-------------------
------------------------TDRAITSFARNC------------------------
--------------------------PAILEIDLHDCKSVTNRSVTSLMATLSNLRELRL
AHCTEINDLAFLELPKQLSMDSLRILDLTACENIRDDAVERIISSAPRLRNLVLAKCRF-
-ITDRAVWAICK-----------------------LGKNLHYIHLGHCSNITDAAVIQLV
KS-CN-----RIRYIDLACCVRLTDRSVQELAT-LPKLRRIGLVKCTLITDRSISALARP
KASPHS-SISSLERVHLSYCVNLTMPGIHALLNNC---PRLTHLS-LTGVQEFLRDELTK
FCREAPPEFTHQQRQVFCVFSGDGVKQLRDHLNRTVPPAREMNEATMYDDDEELDEDEGQ
V------------------------------------TGLMHATAINDDDDDYIDIGHPQ
G-------------------------
>gi|41152474|ref|NP_956400.1|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------MNGI--TKGRFE-------------------------------------
------------------------------------------------------------
----------------VFSNNDEAPINKKLPKELLLRIFSYLD-VVTLC-RCAQVSKAWN
V----LALDG---SNWQKIDLFNFQTDIEGRVVE------NISKRCGG------------
-------------------------------------FLRQLSLRGCLSVGDASMKTFAQ
NC-RNIEHLNLNG-CT--------------------KITDSTC-ISLSKFCFKLRHLDLT
SCVSITNH---------ALKALSE-GCRMLENLNLSWCDQI-------------------
------------------------TSDGIEALSRGC------------------------
--------------------------TALRALFLRGCTQLDDTALKHL-QKH--------
-------------------CPELMTINMQSCTQITDDGFVSLCRGCHKLQMVCISGCSN-
-ITDASLTALGL-----------------------NCQRLKILEAARCSHVTDAGFTVLA
RN-CH-----EMEKMDLEECILVTDNTLVQLSIHCPRLQALSLSHCELITDDGIRHLSSS
-----VCGQERLQVVELDNCPLITDITLEHLK-NC---QRLERIE-LYD-----------
-CQQVSRA---------------GIKRIRAHL------PEIKVHAYFAPVTPPPSVHGGG
Q------------------------------------RLCRCCVIL--------------
--------------------------
>gi|47221169|emb|CAG05490.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MGANNGKLY
GSEGKGSSSISSDIS--SSTDHTPTKA----------PKNVAT-SEGLDSSTR--TLSTP
SPGL---------ILPSKSSSLSSPALSSNGHETNSS---------SSSSAAPETVAVVH
PQPGAHARS-------RQAKGHQHPPIDVLPDHTLLQILSHLP-TNQLC-RCARVCRRWH
N----LAWDP---RLWATIRLTGELLHADRAIRV------LTHRLCQDTPN---------
----------------------------------VCLTLETVVVNGCKRLTDRALYVLAQ
CC-PELRRLEVAG-CY--------------------NISNEAV-FEVVSRCPSVEHLNLS
GCSKVTCISLTQEASL-QLSPLHG-QQISIHFLDMTDCFSL-------------------
------------------------EDEGLRTIASHC------------------------
--------------------------PRLTHLYLRRCARLTDEALRHL-AHH--------
-------------------CPSIKELSLSDCRLVGDFGLREVARLEGCLRYLSVAHCTR-
-ITDVGVRYVAR-----------------------YCPRLRYLNARGCEGLTDHGLSHLA
RS-CP-----KLKSLDVGKCPLVSDCGLEQLAMYCQGLRRVSLRACESVTGRGLKALAA-
---------------------------------NC---CELQLLN-VQD-----------
-C-EVSPE---------------ALRFVR-------------------------------
-------------------------------------RHCRRCIIEHTNPAFY-------
--------------------------
>gi|118086164|ref|XP_418823.2|	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
---------------------------MAELIELGVKKDTYRQWKQGHVAWEEYRNALQT
CRDEILKAKAQVELL--LMADMKINRILHVHWSGETIQRECTS-SDKREGKTG--YNRYG
EGCE--MVGAKSGFCCGIKTEKQWCTVRSEVFLVLEEKERLFMAARRKFQLSDLVILMVE
LNVFLGDTSVINRKFWVFSNNDEALINKKLPKELLLRIFSFLD-IVTLC-RCAQVSKAWN
V----LALDG---SNWQKIDLFNFQTDIEGRVVE------NISKRCGG------------
-------------------------------------FLRQLSLRGCHVVGDSSLKTFAQ
NC-RNIEHLNLNG-CT--------------------KITDSTC-YSLSRFCSKLKHLDLT
SCVAITNS---------SLKGLSE-GCRNLEHLNLSWCDQI-------------------
------------------------TKDGIEALVKGC------------------------
--------------------------SGLKALFLRGCTQLEDEALKHI-QNH--------
-------------------CHELAILNLQSCTQISDEGIVKICRGCHRLQSLCVSGCCN-
-LTDASLTALGL-----------------------NCPRLKILEAARCSQLTDAGFTLLA
RN-CH-----ELEKMDLEECVLITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNS
-----TCGHERLQVLELDNCLLITDVTLEHLE-NC---HNLERIE-LYD-----------
-CQQVTRA---------------GIKRIRAHR------PHVKVHAYFAPVTPPPSVGGSG
Q------------------------------------RLCRCCIIL--------------
--------------------------
>gi|125807702|ref|XP_001360491.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
----------------------MATNTELLPFHHQTTISLQTAAALTNYHGGGGSTAAAS
GAAPSGANGAPVWGM--DELYPQTELPGLTRSAH---HLLRFT-PYALHHRPQ--L-QTL
PPAL---------YLQH-----------------------------AAAAAAAAAAAAAH
AQQPASP---------ESPPPVEGTHISNLFPELLEQIFEHLP-VRDLG-RAAQVCSAWR
D----AAYAK---SVWKGVEAKLHLKRSSPSLFN------CLVRRGIK------------
-------------------------------------KVQILSLR-------RSLKDLVL
GV-PALTSLNLSG-CF--------------------NVADMNLGHAFSVDLPNLKTLDLS
LCKQITDT---------SLGRIAQ-HLRNLENLELGGCCNI-------------------
------------------------TNTGLLLIAWGL------------------------
--------------------------KKLRHLNLRSCWHISDQGIGHL-AGFSRETAEG-
-------------------NLQLEHLGLQDCQRLSDEALGHIAQGLTSLKSINLSFCVS-
-VTDSGLKHLAR------------------------MPKLEQLNLRSCDNISDIGMAYLT
EG-GS-----GINSLDVSFCDKISDQALTHIAQGLYRLRSLSLNQCQ-ITDQGMVKIAK-
-------SLQELENLNIGQCSRITDKGLQTLAEDL---TNLKTID-LYG-----------
-CTQLSSK---------------GIDIIM--------------------KLPKLQKLNLG
L------------------------------------WLVR-------------------
--------------------------
>gi|70990996|ref|XP_750347.1|	Aspergillus fumigatus
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MPRS
RQPLRFSSEVPSESS--SSTSPDRTVD---------DDTDFFM-AQANDSQSSVGVGNFR
EPRD--------------------------------------------------------
----------------QGPRNTVIPPIGRLPPELLISIFAKLSSTADLL-SCMLVCRGWA
ANCVAILWHRPSCNNWDNLKSVTASVGKPDGLFA---YSELIKRLNLSALTED-------
------------------------VSDGTVVPFAQCKRIERLTLTNCSKLTDKGVSDLVE
GN-RHLQALDVSD-LR--------------------YLTDHTL-YTVARNCPRLQGLNIT
GCIRVTDD---------SLIVISQ-NCRQIKRLKLNGVVQV-------------------
------------------------TDRSILSFAENC------------------------
--------------------------PAILEIDLHDCKLVTNPSVTSLMTTLRSLRELRL
AHCVEISDAAFLNLPESLSFDSLRILDLTACENVKDDAVERIVSAAPRLRNLVLAKCRF-
-ITDRAVQAICK-----------------------LGKNLHYVHLGHCSNITDPAVIQLV
KS-CN-----RIRYIDLACCNRLTDNSVQQLAT-LPKLRRIGLVKCQLITDQSILALARP
KVSPDPLGTSSLERVHLSYCVNLTVPGIHALLNNC---PRLTHLS-LTGVQAFLDPAVTQ
FCREAPPEFTQQQREVFCVFSGEGVNRLRDYLNRSPDPPREMTEATMYDDDEELDEDEGQ
V------------------------------------TGLMHATVINDED--YIDIGHAH
G-------------------------
>gi|109076753|ref|XP_001087353.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MR--TLSTP
SPAL---------ICPP--------NLPGFQNGRGSST--------SSSSITGETVAMVH
SPPPTRLTHPLIRL--ASRPQKEQASIDRLPDHSMVQIFSFLP-TNQLC-RCARVCRRWY
N----LAWDP---RLWRTIRLTGETINVDRALKV------LTRRLCQDTPN---------
----------------------------------VCLMLETVTVSGCRRLTDRGLYTIAQ
CC-PELRRLEVSG-CY--------------------NISNEAV-FDVVSLCPNLEHLDVS
GCSKVTCISLTREASI-KLSPLHG-KQISIRYLDMTDCFVL-------------------
------------------------EDEGLHTIAAHC------------------------
--------------------------TQLTHLYLRRCVRLTDEGLRYL-VIY--------
-------------------CASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGR-
-VTDVGIRYVAK-----------------------YCSKLRYLNARGCEGITDHGVEYLA
KN-CT-----KLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAA-
---------------------------------NC---FDLQTLN-VQD-----------
-C-EVSVE---------------ALRFVK-------------------------------
-------------------------------------RHCKRCVIEHTNPAFF-------
--------------------------
>gi|148679324|gb|EDL11271.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------QNCDGGLAA
SGDAHIYPELPASVR--SERGLPC-------------ESDLVL-CSPECPSGA--IKSLG
LRGI---------SCI--------------------------------------------
----------------SLTNLDGSPASHQVLQSVAYHLGPHLE-SLCLG-GGSPTEASFL
A----LILGC---PVLRTLDLSGCNSLFTSGTLL------AQPETAQCVRE---------
----------------------------------ALSGLRDLNLAGLRDLTDLSFNHLSS
CF-PSLERLSLAY-CHLSFELSPTWGSISPQVSSPSQLSFHNLLKFIKERAGTLRALDLS
GTGLPPE----------ALQALGQVTGLKLEELYLHSCRDL-------------------
------------------------SSEAVTILCRQQ------------------------
--------------------------PGLTSLDLSGCSDLTDGALLAV-SRG--------
-------------------LRHLRHLSLKKLQRLTDAGCAALGAL-RELQSLDMAECCL-
-VSGRELAQVLG-------------------SVRRAPRALTSLRLAYCSSLKDASVLSMI
PALGP-----SLKVLDLSSCMALTNQTMQAICTYLIHLSVLRLAWCKELQDWGLLGLKEP
--SDEPVLSPQLHQKVDNEAPDPQEPSSEPQGSSLLMLQALQELD-LTA-----------
-CSKLTDA---------------SLAKV--------------------------------
------------------------------------------------------------
--------------------------
