>gi|73978993|ref|XP_532761.2|	Canis familiaris
-------------------------------------------------MSSAPRR----
----PASGADSFCTPEPESLGPAA-PGFP-EQED-----DELHRTLGVERFEEILQEAGS
RGGEEPGR--SYGEEDF---EYHRQSSHHIHH-----PLSTHLPPDTRRRKTPQGPGRKP
RRRPGASPTGETPTI----------------EEGEEDEEEASEAEGTRA-L-SQPTPAST
PSSVQFFLQEDEGA----DRKGGRTSPSPP-PLPHQEAAPHASKGAQTGAPVEEV-----
----------VAAASGAAGGDDGGASARPLTKAQPGHRSYNLQERRRIGSMTGAE-QALL
PRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSG-QGGREGREP-----
GPTPRTRPRAPHKPHEVFVELNELLLD-RNQEPQWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLL
KHSHPSDEKDFSF-P------------------RNISAGSLGSLLGHHHGQ---GPESD-
---------------------------------------------------PHVTEPLIG
GV---PE---------------------------------------TRLDVERE-RE---
-----------------LPPPAPPAGITRSKS-KHELK----------------------
---------------------LLEKIPENAEATVVLVGCVEFLSRPTMAFVRLR-EAVEL
DAVLEVPVPVRFLFLLLGPSSANMDYH--EIGRSISTLMSDKQFHEAAYLADE----RED
LLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQML----KKREEQGRLLPPGAGLEPK
-SAQDKALL----------QMVEVAGAVE-----DD--------PLRRTGRPFGGLIRDV
RRRYPHYLSDFRDALD-----PQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGV----
SELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSN-NLEYLVGRVWIGFW
LVLLALLMVALEGSFLVRFVS----RFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHGC
-------------------------------------SV-------SNGS----------
---EAHSGDNDTWHGAGATLGPGNG-----------SSPGPVGQGRPRGQPNTALLSLVL
MAGTFFIAFFLRKFKNSRFFPGRVRRVIGDFGVPIAILIMVLV-DYSIED-TYTQKLSVP
SGFSVTAPEKRGWVINPLGENS-SFPVWMMVASLLPAILVFILIFMETQITTLIISKKER
MLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPK-I
QEVKEQRVTGLLVALLVGLSIV--IGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHL
LLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALL--WAVMS-TAASLAFPFILILTVP
LRMVVLTRIFTEREMKCVRNEMHNGERKGL------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|114583557|ref|XP_516113.2|	Pan troglodytes
MGSPENGVLCLQIWVVWRDGSCSLGLKGQAVVLLHVQTSVLCCQHAGMYMAWYTRGPWLA
RPFSGCLSIKVRVPLEEPPLSPDV------EEED-----NDLGKTLAVSRFGDLISKPPA
WDPEKPSR--SYSERDF---EFHRHTSHHTHH-----PLSARLPPPHKLRRLPPTSARHT
RRKRKKEKTSAPPSEGTPPIQEEGG------AGVDEEEEEEEEEEGESEAEPVEPPPSGT
PQKAKFSIGSDEDDSPGLPGRAAVTKPLPSVGPHTDRSPQHSS-----------------
----------SSPSPRARASRLAGEKSRPWSPSA----SYDLRERLCPGSAVGNP-GGPE
QQVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRTQGGRGSPSGLAP----I
LRRKKKKKKLDRRPHEVFVELNELMLD-RSQEPHWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTIAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLL
KHSHPNDDKDSGFFP------------------RNPSSSSMNSVLGNHHPT----PSHG-
---------------------------------------------------PDGAVPTMA
DDLGEPA---------------------------------------PLWPHDPDAKE---
-----------------KPLHMPGGDGHRGKSLK--------------------------
---------------------LLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLN-EAVLL
ESVLEVPVPVRFLFVMLGPSHTSTDYH--ELGRSIATLMSDKLFHEAAYQADD----RQD
LLSAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELL----RKRREREQTKVEMTTRGGY
TAPGKELSL----------ELGGSEATPE-----DD--------PLLRTGSVFGGLVRDV
RRRYPHYPSDLRDALH-----SQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGV----
SELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQ-DLEYLTGRVWVGLW
LVVFVLALVAAEGSFLVRYIS----PFTQEIFAFLISLIFIYETFYKLYKVFTEHPLLPF
-Y-------------------------------PPEGAL-------EGSL----------
--DA--------GLEPNGSALPPTE--------------GPP---SPRNQPNTALLSLIL
MLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLV-DYSITD-TYTQKLTVP
TGLSVTSPDKRSWFIPPLGSAR-PFPPWMMVAAAVPALLVLILIFMETQITALIVSQKAR
RLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQ-I
QEVREQRVTGVLIASLVGLSIV--MGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLL
ILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALL--WVVKS-TAASLAFPFLLLLTVP
LRHCLLPRLFQDRELQALDSEDAEPNFDEDG------------------------QDEYN
ELHMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|156541044|ref|XP_001603420.	Nasonia vitripennis
---------------------------------------------MGFGALGSREKECMN
QGWTSGEHVWERRAARPWMQPGAGAGGGGGHQPA-----AGGQGGGGGTGDDEAPKDPGA
RITHQSH---QYTEKDF---EGHRAHTVYVGV---------HLPGERRHRRHHKHHHSRN
-------------------------------GSGKEGESEG------------DRPVTPP
AQRVQFILGEDVGD----D-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------AHESHPLFSEMEELVKD--GDEMEWKETARWIKFEEDVEEGGNRWSKPHV
ATLSLHSLFELRSLLLNGTVMLDMEASGLEQITDLVLDNMVNKSVLSINVKDKVREALLV
RHRHQFERRKDNNMS------------------RLPIIRSLAEIGRNHSSSKKPWHYST-
---------------------------------------------------QFLNTCDSQ
KFSDCDCSCGMHALLTSDFQERRDNGDAYAPAVARSTSCPDSNTALLSKEAKDLKGPYLL
-----------------VPGQEPGPMGIDRSPSSMSISRNHSSSALENGDANHRGNTH--
---------------------FMRKIPAGAEASNILVGEVDFLDKTLSAFIRLS-QASIM
GDLTEVPVPTRFIFILLGPTGGISSFH--EIGRAMATLMSDEVFHDVAYKAKN----RNH
LLAGIDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQDT----RKRPKEEKLEEIDEEADEQ
-KLRD-----------------------------ES--------GLSRTGRLFGGLINDV
KRKAPVYFSDFKDAVA-----LQCVASFIFLYFACLSPIITFGGLLSEATGKNMAA----
MESLVSGFVCGLGYGFFSGQPLTILGSTGPVLVFETIVFEFCKKY-DWDYMSFRFWIGTW
ITIILIILVAIDASALVCYIT----RFTEENFATLIAFIFIYKAVENVLTIGKKFPINPH
ATDVNFSSNYELCLCK-----------------PPNSTL-------NLLP----------
-----PGHEHVNWSAMSRIACQNFN----------GTVIDDC--HQPHYVPDVFLMSIIL
FMGTFLVSVELKDFKNALFFPSKVRAIVSDFAVIIAIFSMSLM-DYFVG--IATPKLEVP
AEFKPTLDG-RGWMIWPFNRN----PWWSALIAVAPALLGTILIFMDQQITAVIVNRKEN
KLKKGCGYHLDLFVLAILIEICSIMGLPWFVAATVLSINHVNSLKLESECAAPGEKPQ-F
LGVREQRVTHILIFLMIGCSVF--LTPMLKHIPMPVLFGVFLYMGVASLKGLQFFDRIMI
MLMPVKYQPDYMFLRQVPLKRVHLFTLIQLTCLACL--WIIKSFSSTSILFPLMLVVMIG
IRK-SLDLLFTQRELKILDDVMPEPHKKHAEDLRQLENG----------EEHNDSIGFAS
SGNLQI-------PLANGNIMKIPLTSIN---ISEEVNKTGIWQQVNEGNDKNKQSNKLI
NVGKQKKHSKKDAVLSTDETTRLTTMTEEDEDDGGISIKVDLIRSKDTSPFKANGTTSAE
TSV----------------------------------
>gi|157016003|gb|EAL40007.3|	Anopheles gambiae
--------------------------------------------------RCLARYTVVL
IAARLIVVCTSNDDPNEVHLDDEIERVFGTTAEKERFELNRLQDEVILDNSPLKYDEAHR
VPDSADATSSASNNNNN---NNNSSSTTSNNK-----PSASSNEQQGRSKPVAASPPTTT
PTSPISFSSKSEPT-----------------DTKLSSTANNTTLADNTSNDFSETVHDEP
VVDQGTVQGEQWDT----SARRNVHFDKDNKGAPIEGLPL--------------------
------------------EDTNEERRRRTERHHPHKSRKFSLQEYHPEWRRQSGTEGGPT
GRRISVQPEDATLQEADIDELTSHRSDDPRALRRHKVSAQSGASLVNINRKEAAPPLQHL
LPSSKYKKMYDHSPHEVFVQLDELTGS--GEDREWKETARWIKYEEDVEEGADRWGRPHV
ASLSFHSLLNLRRCLETGVVLMDLEEKDLPSVAYRVVEQMVVDELIHEDDKAVIMRALLL
RHRHVNESSHGGFSF-----------------GPKRKYSSYTSLQVSRPGPQQPAHQPA-
---------------------------------------------------KDQQRHQRH
ASGPHRCRRSGSQDSSSTATAAAAPVTLTTVTSAVGMRRNNSPLSLTSVDDKKP-RI---
-----------------VPATEINGHGGGHGETRINISEETYTSSQEDIKMRT-------
------QKES-----------ILKRIPEGAEATTVLVGAVDFLEQPTIAFVRLA-EGIPM
PSITEVPIPVRFLFILLGPQKTELDYH--EVGRSIATLMSNEHFHDIAYKADD----RRQ
LLSAINEFLDDSIVLPPGKWERQALLPFEELKAKSDMIRLRKKKALDEKIKSKQSQLLTS
EEEKKLLAAAG--------GAGDGGGGGDGKKPPKN--------PLEKTNRLWGGLINDI
KRRYPMYKSDIMDGLN-----TETLAATIFMYFAALSTAITFGGLSSDKTHNLIGI----
SETLVSASMVGLVFHLLAGQPLVIIGTTGPLLLFDEALNQFCISN-DFSFLTVRVYVGCW
LAVIALVVSAFEGSVYVRLFT----RFTQEIFSALITLIYIVETVMKLLSVYKRHPLLAE
-YLYKNVTEPQPLPMPYLEEE------------RNGTTP-------TSEL----------
--LAESLTTAVNGTIAMAQDAANLL----------IPEDGTG----PLNRPNTALFCTIL
TLGTFSLAYYLKLFRNSHFLGRNARRALGDFGVPISIALFVLV-DYMIPQ-VYTEKLSVP
EGLSPSDETRRGWII-PLGGV----PGWMPFVAGIPALLVYILIFMETHISELIVDKPER
GLKKGSGLHMDIVLLCFLNTVCGFFGMPWHCAATVRSVTHVSAVTIMSRTHAPGDAPH-I
TDVKEQRISGFFVSLMVGLSVT--MAPILRLIPMSVLFGVFLYMGIASMSGVQFFERLRL
YLMPVKHHPQVPFVRRVPTWKMHLFTFVQILALAML--WAVKS-SPFSLAFPFFLIMMVP
IRK-QLESIFSPLELRALDGSQPNEGAEDE-------------------------PDFYE
QAPIPA------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|24266569|gb|AAN52239.1|AF43	Oncorhynchus mykiss
------------------------------------------------------------
-----------------------------MSTDK-----NKVEDEAVLDRGACFVKH---
----------VCDEEEV---EGHH--TVYIGV-----HVPKSYQRRRRHRRKSSHKERKG
RP-----------------------------ADNVEGDKSDGENADEAAPNILKPLISAA
AERIRFILGEEDDG----P-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------PPPQLLTELDELLAV-DGQEMEWKETARWIKFEEKEEKGGERWSKPHV
ATLSLHSLFELKTCIEKGTILLDLEASTLPQVVELITDSQIEIGQLKPELKDQVMYTLLR
KHRHQT---------------------------KKSNLRSLADIGKTVSSASRLFSNQD-
---------------------------------------------------QNGSPATAH
------------------------------------------------------------
-----------------RNLTSNSLNDFSDQPDRDQLKNK--------------------
---------------------LMKKLPRDAEASNVLVGGVDFLDTPFVAFVRLQ-QAAML
GGLTEVPVPTRFLFVLLGPKSKAKSYH--EIGRAIATLMSDEVFHDIAYKAKD----RQD
LLAGIEEFLDEVIVLPPGEWDPDIRIEPPKSLPSSDK----RKNQYNAGGGGDGPQMNGD
TPGHDG-------------GQGGGGGHGHV----GE--------ELMNTGKFCGGLILDI
KRKLPFFASDFYDAIH-----IQSLSAILFIYLGTVTNAITFGGLLGDATENMQGV----
LESFLGTALTGAIFCLLGGQPLTILSSTGPVLVFERLLFNFSKDH-DFDYLEFRLWIGLW
SAFFCLVLVATDASSLVKYFT----RFTEEGFSSLISFIFIYDAFKKMLKLAHYNPINAD
-YDPNYVTMYD-CRCMPP---------------PDDGNMTGLYIDASAWI----------
--NNADLSVNATWASLDKKQCVVYG----------GELIGPA----CGFVPDVTLMSFIL
FLGTYTCSMSLKKFKFSRFFPTTVRKLISDFAIILTIVIFCGV-DAFVG--VDTPKLIVP
TEFKPTSPN-RGWFVPPFGGN----PWWVYLAAALPALLVTILVFMDQQITAVIVNRKEH
KLKKGAGYHLDLFWVAILLIVCSFMGLPWYVAATVISIAHIDSLKMETQCSAPGEQPK-F
LGVREQRVTGVFVFVLTGLSVF--MAPILKFIPMPVLYGVFLYMGVASLNGVQFLDRLQL
LLMPAKHQPDLIYLRHVPQRRIHLFTFIQALCLALL--WVLKS-TVAAIIFPVMILALVA
VRK-AMDYIFSQQDLSYLDDVIPEKDKKKKEDEKRKKKQ----------KKGSIDSEIDF
PPEYPYND--------------KIPSIKI---SMDIMETEPMLGN---------------
---------KDKASDRPPSSFRDQHSPC--------------------------------
-------------------------------------
>gi|109068869|ref|XP_001103478.	Macaca mulatta
-------------------------------------------------MSSAPRC----
----PTKGADSFRTPEPESLGPGT-PGFPEQEE------DELHRTLGVERFEEILHEAGS
RGGEEPGR--SYGEEDF---EYHRQSSHHIHH-----PLSTHLPPDARRRKTPQGPGRKP
RRRPGASPTGETPTI----------------EEGEEDEDEASEAEGARAVT--QPSPAST
PSSVQFFLQEDDSA----DRKAERTSPSSPAPLPHQEATPRASK----------------
------------------GAQAGGSNSQYW------------------------------
-----------------LRYWTGHRFEDVPGVRRHLVRKNAKGST-QSGREGREP-----
GPTPRARPRAPHKPHEVFVELNELLLD-KNQEPQWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLL
KHSHPSDEKDFSF-P------------------RNISAGSLGSLLGHHHGQ---GAESD-
---------------------------------------------------PHVTEPLIG
GV---PE---------------------------------------TRLEVERE-RE---
-----------------LPPPAPPGGITRSKS-KHELK----------------------
---------------------LLEKIPENAEATVVLVGCVEFLSRPTMAFVRLR-EAVEL
DAVLEVPVPVRFLFLLLGPSSANMDYH--EIGRSISTLMSDKQFHEAAYLADE----RDD
LLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQML----KKREEQGRLLPTGAGLEPK
-SAQDKALL----------QMVEAAGAAE-----DD--------PLRRTGRPFGGLIRDV
RRRYPHYLSDFRDALD-----PQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGV----
SELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSN-HLEYLVGRVWIGFW
LVLLALLMVALEGSFLVRFVS----RFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGC
--------------------------------------S-------ASNS----------
--SEVDGGENMTWAGARPTLGPGNR-----------SLAGQSGQGKPRGQPNTALLSLVL
MAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLV-DYSIED-TYTQKLSVP
SGFSVTAPEKRGWVINPLGEKS-PFPVWMMVASLLPAILVFILIFMETQITTLIISKKER
MLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPK-I
QEVKEQRVTGLLVALLVGLSIV--IGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHL
LLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALL--WAVMS-TAASLAFPFILILTVP
LRMVVLTRIFTEREMKCLDANEAEPVFDEREG-----------------------VDEYN
EMPMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|51328345|gb|AAH80271.1|	Mus musculus
---------------------------------------------MANGVIPPPGG----
----ASPLPQVRVPLEEPPLGPDV------EEED-----DDLGKTLAVSRFGDLISKTPA
WDPEKPSR--SYSERDF---EFHRHTSHHTHH-----PLSARLPPPHKLRRPPPTSARHT
RRKRKKEKTSAPPSEGTPPIQEEGG------AGAEEEEEEEEEEEGESEAEPVEPLPPGP
PQKAKFSIGSDEDDSPGLPVKAPCAKALPSVGLQSDQSPQRSG-----------------
----------SSPSPRARASRISTEKSRPWSPSA----SYDLRERLCPGSALGNP--GPE
QRVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRIQGGRGSPSGLA----PI
LRRKKKKKKLDRRPHEVFVELNELMLD-RSQEPHWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTIAQGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLL
KHSHPNDDKDSGFFP------------------RNPSSSSVNSVLGNHHPT----PSHG-
---------------------------------------------------PDGAVPTMA
DDQGEPA---------------------------------------PLWPHDPDAKE---
-----------------KPLHMPGGDGHRGKS----LK----------------------
---------------------LLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLS-EAVLL
ESVLEVPVPVRFLFVMLGPSHTSTDYH--ELGRSIATLMSDKLFHEAAYQADD----RQD
LLGAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELL----RKRREREQTKVEMTTRGGY
AAPGKELSL----------EMGGSEATSE-----DD--------PLQRTGSVFGGLVRDV
KRRYPHYPSDLRDALH-----SQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGV----
SELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQ-DLEYLTGRVWVGLW
LVVFVLALVAAEGSFLVRYIS----PFTQEIFAFLISLIFIYETFHKLYKVFTEHPLLPF
-Y-------------------------------PPDEAL-------ET------------
------------GLELNSSALPPTE--------------GPP---GPRNQPNTALLSLIL
MLGTFLIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLV-DYSITD-TYTQKLTVP
TGLSVTSPHKRTWFIPPLGSAR-PFPPWMMVAAAVPALLVLILIFMETQITALIVSQKAR
RLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQ-I
QEVREQRVTGVLIASLVGLSIV--MGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLL
IFMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALL--WVVKS-TAASLAFPFLLLLTVP
LRRCLLPRLFQDRELQALDSEDARWSGRVQRAAHACVTC----------RMVPL-RDPTL
AIHRP-------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|45384448|ref|NP_990294.1|	Gallus gallus
-------------------------------------------------MSRSPVSSEL-
----HHIVSSAIESPEPPAPGPAS-PPLA-EEEE-----KDLNKALGVERFEEILSDAHP
RSVEEPGR--IYGEEDF---EYHRQSSLHIHH-----PLSAHLPPDARRKKGVPKKGRKK
RGR--AAAPGENPPI----------------EEGEEDEEEACDTETERS---AEELRGGP
AEGVQFFLQEDEVT----ERRAE-EPPAPPAP-PGPTAEPHGATAPAAASPGAEE-----
----------GRAADGGAVPEDGGSPGRPAARATE-HRSYNLHERRRIGSMTGAD-EAQY
QKVPTDESEAQTLASADLDYMKSHRFEDVPGVRRHLVRKSAKAQVVHVGKEHREQ-----
SARPR---RSDRQPHEVFVELNELVLD-KNQELQWKETARWIKFEEDVEEETDRWGKPHV
ASLSFRSLLELRKTLSHGAVLLDLDQKTLPGVAHQVVEQMVITDQIRAEDRANVLRALLL
KHSHPSDEKEFSF-P------------------RNISAGSLGSLLVHHHSTNHVGEGGE-
---------------------------------------------------PAVTEPLIA
GHGAEHD---------------------------------------ARVDVERE-RE---
-----------------VPTPAPPAGITRSKS-KHELK----------------------
---------------------LLEKIPDNAEATVVLVGCVEFLDQPTMAFVRLQ-EAVEL
DSVLEVPVPVRFLFLLLGPSSTHMDYH--EIGRSISTLMSDKQFHEAAYLADD----RHD
LLTAINEFLDCSVVVPPSEVQGEE-LRSVAHFQREML----KKREEQEK----RMLLEPK
-SPEEKALL----------KLKVAEDEDE-----DD--------PLRRTGRPFGGLIRDV
RRRYPHYLSDFRDALN-----PQCIAAVIFIYFAALSPAITFGGLLGEKTQDLIGV----
SELIISTSLQGVLFCLLGAQPLLVIGFSGPLLVFEEAFFTFCTSN-GLEYLVGRVWIGFW
LILIVLLMVACEGSFLVRFVS----RFTQEIFAFLISLIFIYETFSKLGKIFQEHPLHGC
------------------------------------------------------------
--------AQPNGTAWSNGTAAPNG----------TAQRGAA---KVTGQPNTALLSLVL
MAGTFFIAFFLRKFKNSRFFPGRIRRLIGDFGVPIAILVMVLV-DYSIRD-TYTQKLSVP
SGFSVTAPDKRGWVINPLGERS-DFPVWMMVASGLPAVLVFILIFMETQITTLIISKKER
MLQKGSGFHLDLLLIVAMGGFFALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPK-I
QEVKEQRVTGLLVAVLVGLSIV--IGELLRQIPLAVLFGIFLYMGVTSLNGIQFYERLQL
LLMPPKHHPDVPYVKKVRT-RMHLFTGLQLACLAVL--WAVMS-TVASLAFPFILILTVP
VRMCLLSRIFTDREMKCLDADEAEPILDEREG-----------------------VDEYN
EMPMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|126723591|ref|NP_001075788.	Oryctolagus cuniculus
-------------------------------------------------MSSAPRR----
----PASGADSFRTPEPESLGPGT-PGFP-EQEE-----DELHRTLGVERFEEILQEAGS
RGGEEPGR--SYGEEDF---EYHRQSSHHIHH-----PLSTHLPPDARRRKTPQGPGRKP
RRRPGASPTGATPTI----------------EEGEEDEEEANEAEGARA-P-TEPSPAST
PSSVQFFLQEDEGA----ERKAERTSPSPPTLLPHQEAAPWATEGAQTGVPVEEV-----
----------AVVASGTAGGDNGGASGRPLTKAQPGHRSYNLQERRRIGSMTGAE-QALL
PRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSA-QSSREGREP-----
GPTPRSRPRAPHKPHEVFVELNELLLD-KNQEPQWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLL
KHSHPSDEKDFSF-P------------------RNISAGSLGSLLGHHHGQ---GAESD-
---------------------------------------------------PHVTEPLIG
GI---PE---------------------------------------TRLDVERE-RD---
-----------------VPPSAPPAGITRSKS-KHELK----------------------
---------------------LLEKIPENAEATVVLVGCVEFLSRPTMAFVRLR-EAVEL
DAVLEVPVPVRFLFLLLGPSSANMDYH--EIGRSISTLMSDKQFHEAAYLADE----RED
LLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQML----KKREEQGRLLPPGLGLEPK
-SAQDKALL----------QMVEAAGAAE-----DD--------PLRRTGRPFGGLIRDV
RRRYPHYLSDFRDALD-----PQCVAAVIFIYFAALSPAITFGGLLGEKTQDLIGV----
SELIMSTALQGVIFCLLGAQPLLVIGFSGPLLVFEEAFFTFCSSN-QLEYLVGRVWIGFW
LVLLALLMVALEGSFLVRFVS----RFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHGC
-------------------------------------SV-------SNSS----------
---ETDSSENATWAGAGSTLGPANR-----------SSAGQAGQGRPRGQPNTALLSLVL
MAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLV-DYSIED-TYTQKLSVP
SGFSVTAPDKRGWVINPLGEKS-PFPVWMMVASLLPAILVFILIFMETQITTLIISKKER
MLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPK-I
QEVKEQRVTGLLVALLVGLSIV--IGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHL
LLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALL--WAVMS-TAASLAFPFILILTVP
LRMVVLTRIFTEREMKCLDANEAEPVFDEREG-----------------------VDEYN
EMPMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|119891698|ref|XP_586817.3|	Bos taurus
---------------------------------------------------MGPARVLMA
QDSGGGAGKAAGGRPEPESLGPVTAPGFAAEQEE-----DELHRTLGVERFEEILQEAGS
RGGEELGR--SYGEEDF---EYHRQSSHHIHH-----PLSTHLPPDTRRRKTPQGPGRKP
RRRPGASPTGETPTI----------------EEGEEEEDEASEAEGARALS--QPSPAST
PSSVQFFLQEDEGA----DRKAETTSPSPPPPLPHQEAAPRATKAAQTGAQVEEV-----
----------VAVASGTAGGDDGGASGRLLTKAQPGHRSYNLQERRRIGSMTGAE-QALL
PRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKASV-QSGREGREP-----
GPTPRARPRAPHKPHEVFVELNELLLD-KNQEPQWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLL
KHSHPSDEKDFSF-P------------------RNISAGSLGSLLGHHHGQ---GAESD-
---------------------------------------------------PHVTEPLIG
GV---PE---------------------------------------TRLEVERE-RE---
-----------------PPPPAPPAGITRSKS-KHELK----------------------
---------------------LLEKIPENAEATVVLVGCVEFLARPTMAFVRLR-EAVEL
DAVLEVPVPVRFLFLLLGPSSANMDYH--EIGRSISTLMSDKQFHEAAYLADE----RED
LLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQML----KKREEQGRLLPPGAGLEPK
-SAQDKALL----------QMVEVAGAVE-----DD--------PLRRTGRPFGGLIRDV
RRRYPHYLSDFRDALD-----PQCLAAVIFIYFAALSPAITFGGLLGEKTHDLIGV----
SELIMSTAIQGVLFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSN-NLEYLVGRVWIGLW
LVLLALLMVALEGSFLVRFVS----RFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGC
-------------------------------------SV-------SNSS----------
--EAGSG-ENATWPGAGATLGPRNE----------SSARPPG-QGRPRGQPNTALLSLVL
MAGTFFIAFFLRKFKNSRFFPGRVRRVIGDFGVPIAILVMVLV-DYSIED-TYTQKLSVP
SGFSVTAPEKRGWVINPLGEKS-TFPVWMMVASLLPAILVFILIFMETQITTLIISKKER
MLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPK-I
QEVKEQRVTGLLVALLVGLSLV--IGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHL
LLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLAVL--WAVMS-TAASLAFPFILILTVP
LRMVVLTRIFTEREMKYLDANEAEPVFDEREG-----------------------VDEYN
EMPMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|51704116|gb|AAH81116.1|	Xenopus laevis
------------------------------------------------------------
------------------------------MDEDRYG--EQMRPLLTTGHDEEAIVDLGK
TSSSVNT---NFEKEEL---ESHR--AVYIGV-----HVPFARQSHRRHKHRGHRHHRRR
REK----------------------------ENDKEDGRE-------------SPNYDTP
SQRVQFILGTEDDD----E-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------EHIPHDLFTEMDELCFR-DGEECEWKETARWLKFEEDVEDGGDRWSKPYV
ATLSLHSLFELRSCILNGTIMLDMRANTIEDISDMLLDNLTASGQMDESIREQVREALLK
RHHHQNEKKLSN---------------------RIPLVRSFADIGLLSSPQSVSGNLDS-
---------------------------------------------------SKSSELK--
------------------------------------------------------------
-----------------RNPTGGSLENSTVDFSKVDMN----------------------
---------------------FMRKIPAGAEASNVLVGEVDFLDRPIIAFVRLC-PAVLL
SGLTEVPIPTRFLFILLGPTGKGGPYH--EIGRSIATLMTDEIFHDVAYKAKD----RND
LLAGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEK----RK----IPTIPNGSTPPGE
TIKEEQHLT-------------------------GP--------ELQRTGRLFGGLMLDI
KRKAPFFLSDFKDALN-----LQCLASVLFLYCACMSPVITFGGLLGEATQNRISA----
IESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDY-ELSYLSLRTSIGLW
TAFLCLLLVATDASSLVCYIT----RFTEEAFAALICLIFIYEALEKLFDLGEKYAFNMN
-NDLDLLSKYT-CMCTEPLN-------------PNNETL-------ALWS----------
--KANITASEVPWNNLTVTDCVHLN----------GTFVGSACGHHGPYIPDVFFWSVIL
FFTTFFLSSFLKQFKTKNYFPTKVRSTISDFAVFLTIVIMVLI-DYLVG--IPSPKLHVP
EKFEPTLKD-RGWIIDPLGKN----PWWTLLAAAIPALLCTILIFMDQQITAVIINRKEH
KLKKGGGYHLDLFVVAIMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPK-F
LGIREQRVTGLLIFVLMGLSVF--MTSVLKFIPMPVLYGVFLYMGASSLKGIQLFDRIKL
FGMPAKHQTDLIYLRYVPLWKVHVFTVIQLTCLVLL--WVIKA-SSAAVVFPMMVLALVF
IRK-LLDFIFTKRELSWLDDLMPESKKKKEDDKKKKKK----------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|18147588|dbj|BAB83084.1|	Tribolodon hakonensis
------------------------------------------------------------
------------------------------MSDK-----NKMEDEAIVDRGASYIK----
----------NVCDEEV---EGHH--TVYIGV-----HVPKSYRRRRRNRRRSNHKERRE
R------------------------------VTENVSDKSDTENADDPSSSILKPLISPA
AERIRFILGEDDSG----P-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------PPPQLFTELDELLSV-DGQEMEWKETARWIKFEEKVEKGGERWSKPHV
ATLSLHSLFQLKNCIEKGTIMLDMEANSLQQIVEMITDSQIENGQLKADLKEMVMYTLLR
KHRHQT---------------------------KKSNLRSLADIGKSVSSASRLFTNQE-
----------------------------------------------------NGSPTTAH
------------------------------------------------------------
-----------------RNLTSNSLNDLADKPEKDQLNNK--------------------
---------------------FMKKIPRDAEASNVLVGEVDFLDSPFVAFVRLQ-QSVML
GGLTEVPVPTRFLFILLGPKGKANSYR--EIGRAIATLMSDEVFHDIAYKAKG----RGD
LLAGIDEFLDEVIVLPPGEWDPDIRIEPPKSIPSADK----RK---NIIAGGEGSQMNGG
-TPHDG-------------SPGGGGGHAV-----GD--------ELKMTGKFCGGLILDI
KRKLPFFASDFYDAIH-----IQSLSAILFIYLGTVTNAITFGGLLGDATENMQGV----
LESFLGTALTGAVFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN-DFDYLEFRLWIGLW
SGFLCLILVATDASFLVQYFT----RFTEEGFSALISFIFIYDAFKKMIKLAHHHPINSG
-YNIDLVTQYG-CHCSP----------------PDSETI-------SNSSGLYMEKMEGL
MNSTGQHHLNATWMSLSRSECLDWG----------GQLLGPA----CEYVPDITLMSFIL
FFGTYTCSMGLKKFKTSRFFPTTIRKLISDFAIILAIFIFCGV-DALVG--VDTPKLIVP
SEFKPTSPH-RGWFVPPFGGN----PWWVCLVSVLPALLVTILVFMDQQITAVIVNRKEH
KLKKGAGYHLDLFWVSILLILCSFMGLPWYVAATVISIAHIDSIKMETETSAPGEQPK-F
LGVREQRVTGIMVFILTGLSVL--MAPVLKFIPMPVLYGVFLYMGVASLNGVQFMDRLQL
LLMPAKHQPDLIYLRHVPLRRVHLFTFLQVLCLALL--WILKS-TVAAIIFPVMILALVA
VRK-AMDYVFSQHDLSYLDDVMPEKDKKKKEDEKKKKK-----------KKGSIDSDMND
S-DFPAIE--------------NVPSIKI---SMETMEQDPVLGE---------------
---------KPSDRNKPMSFL----TPY--------------------------------
-------------------------------------
>gi|9789737|sp|Q9Z0S8|B3A2_CAVP	Cavia porcellus
-------------------------------------------------MSGTPRR----
----PASGADSFHKPEPEIVGPGT-PGFP-EQEE-----DDLHRTLGVERFEEILQEAGS
RGGEELGR--SYGEEDF---EYHRQSSHHIHH-----PLSTHLPPDARRRKTPQGQVRKP
RRRPGATPAGETPTI----------------EEGEEDEDETSEAEGPVS-H-TDPSPAST
PTSVQFFLQEDEGT----DRKAERTSPSPPAQLPHQEAAPQATKKAQPDALVEEA-----
----------IMVSGGTAGGDDGGASGRPLSKAQPGHRSYNLQERRRIGSMTGVE-QALL
PRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSS-QSSREGREP-----
GPTPRTRPRAPHKPHEVFVELNELLLD-KNQEPQWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLL
KHSHPSDEKEFSF-P------------------RNISAGSLGSLLGHHHTQ---GAESD-
---------------------------------------------------PHVTEPLIG
GV---PE---------------------------------------TRLEVERE-RE---
-----------------LPPPAPPAGITRSKS-KHELK----------------------
---------------------LLEKIPENAEATVVLVGCVEFLSRPTMAFVRLR-EAVEL
DAVLEVPVPVRFLFLLLGPSSANMDYH--EIGRSISTLMSDKQFHEAAYLADE----RED
LLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQML----KKREEQGRLLPPGVGLEPK
-SAQEKAFL----------QMVEAVGAVED----DD--------PLRRTGRPFGGLIRDV
KRRYPHYLSDFRDALD-----PQCLAAVIFIYFAALSPAITFGGLLGEKTHDLIGV----
SELIMSTALQGVTFCLLGAQPLLVIGFSGPLLVFEEAFYSFCRSN-ELEYLVGRVWIGFW
LVLSALLMVALEGSFLVRFGS----RFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGC
--------------------------------------L-------ASNS----------
--SEADGGKNTTWTEAAPTPGHGNT----------SSAEQAG-VERPQGQPNTALLSLVL
MAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLV-DYSIQD-TYTQKLSVP
SGFSVTAPEKRGWIINPLGEEE-PFPVWMMVASLLPAILVFILIFMETQITTLIISKKER
MLQKGSGFHLDLLLIVAMGGICALFGLLWLAAATVRSVTHANALTVMSKAVAPGDKPK-I
QEVKEQRVTGLLVALLVGLSLV--IGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHL
LLMPPKHHPDVMYVKKVRTMRMHLFKALQLLCLALL--WAVMS-TAASLAFPFILILTVP
LRMVVLTRIFTEREMKCLDANEAEPVFDEREG-----------------------VDEYN
EMPMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|126337764|ref|XP_001362217.	Monodelphis domestica
---------------------------------------------MANGLIPPPGG----
----TSPLPQVRVPLEELPLSPD-------REED-----DDLGKTLAVSRFGDLISKLPA
WDPEKPSR--SYSERDF---EFHRHTSHHTHH-----PLSARLPPPHKFRRLPTTSAHRA
RRKRKKEKTSAPPSEGTPPIQEEGVVGGEEEEEEEEEEEEEEEGESEAETLDQEPLPAES
PSRVKFSIGSDDDD----SVGVPGKNVPTKSLSQPLPGLAHDSEHSSRYCPSVKDMGEGS
RGLFSTSSP-SPPIPRPRTPRGMDEKARPWSPSA----SYDLRERLCPGSALESP-VSLE
QQVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRTQAGRSSPGGLAP----I
LRKKKKKKKLDRRPHEVFVELNELMLD-KAQEPQWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRKTIAHGATLLDLEQTTLPGIAHLVVETMIMSDQIRPEDRASVLRTLLL
KHSHPNDDKDGSFFP------------------RNPSSSSVNSMLGNHHST----PGHV-
---------------------------------------------------PDSAVPTIG
DDLSEPA---------------------------------------PLWPHDPDSRE---
-----------------KPLHMPGGDGHRGKSLK--------------------------
---------------------LMEKIPEDAEATVVLVGCVPFLEQPAAAFVRLN-EAVLL
ESVLEVPVPVRFLFVMLGPRETRTDYH--ELGRSIATLMSDKLFHEAAYQADD----RQD
LLCAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELL----RKRREREQNKVQLAPRSET
TVSGKDLSTS---------GSGVSEGSPE-----DD--------PLQRTGSLFGGLIQDV
KRRYPLYVSDLIDALD-----SQCLAAVLFIYFAALSPAITFGGLLGEKTEGLIGV----
SEMIVSTSIIGVIFSLLAAQPLLVVGFSGPLLVFEEAFFKFCHAQ-DLEYLTSRVWVGFW
LIVFVVSLVAIEGSFLVRYIS----LFTQEIFAFLISLIFIYETFYKLYKVFTEHPLLPF
-Y-------------------------------PSDSAL-------ERPI----------
--GSD--------LDLNSSALPTTE--------------GPP---GPRKQPNTALLSLIL
MLGTFLLAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLV-DYSIID-TYTQRLTVP
TGLSVTSPDKRSWFIPPLGSTR-PFPPWMMVAASIPALLVLILIFMETQITALIVSQKAR
RLVKGSGFHLDLLLIGSLGGLCGLFGMPWLTATTVRSVTHVNALSVMRTAIAPGEKPQ-I
KKVREQRVTGLLISCLVGLSIV--MGPMLRRIPLAVLFGIFLYMGVTSLIGIQLSQRLLL
LLMPAKHHPDEPYVTKVKTWRMHLFTCIQLGCIAVL--WVVKS-TAASLAFPFLLLLTVP
LRRCLLPRIFKERELQALDSVEAEPNFDEDG------------------------QDEYN
ELHMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|24661908|ref|NP_648357.1|	Drosophila melanogaster
------------------------------------------------------------
---------------------------------------MSFSSASGRENNVRKLSFLGF
NTKKKSGN--EDPDEVL---LDSEMDKVFAGN-----SARKDKFDVNTFQDNSQLPIGSR
KKNSIRT------------------------NDLNIEEDSEYESQTEPLNN--AQNYDDI
PEDFPLVSERAGHG----DHSDNSVDEKHVQFGGKKKIPP--------------------
----------SLSYDEQPTDQSHERKRRRSRHQYYRQRKFSHQDSVEPKNKLEEN-GDAG
ARRISVQPEDTALEEADLNELRSHRSDDPRALRRHKIH--------HSSIKLRELPQITI
SPFTNKKPEVDHSPHEIFVQLDELTGV--GEDREWKETARWIKYEEDVEEGSDRWGKPHV
ASLSFHSLLNLRRCLETGVVLLDLNEKDLPAVAYRVVEQMVIEDLIDINDKPSVMRSLLL
RHRHVNEHQGVLPFT----------------KRKYNSYTSLQFLWMGADSAHQPYQQAQ-
-------------------------------------------------------PPPRN
LAKARRSICVTSSAPPTAAMLNVATATAAAAAIDHRRHSTMSYLGNLSGTDDKKIK----
-----------------IMPAAEIGGSKRSNELKIDMKDDMYSSSQEDLKKLQNDT----
---------------------ILKRIPAGAEATTVLVGAVEFLEQPTIAFVRLS-EGVLM
PTLTEVPVPVRFMFVLLGPRNFDLDYH--EVGRSISTLMANEHFHSIAYKADD----RKD
LLSAINEFLDDSIVLPPGNWDRHDLLPFEELKAKKDWI---RTRKIKALQVKRDSEMIKI
GKDEEKALLEKQTLGAIGFTIGGGDGGGDGDSDDDNGRKKKKPSPLEKTGRLWGGLRNDL
KRRMPMYKSDILDGLN-----TETLAATIFMYFACLSTAITFGGLVSAKTNSWIGI----
SETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQH-EFDFLSLRVYVGVW
LIIIALTVSAFEGSVYVRLLT----RFTQEIFSALITLIYIVETFMKLISIYRENPLLSD
-YNL-----------------------------PPPTLV-------AHEH----------
--ATNESLLNATASVTTNITQMVMN------ISTTAMPIGPP--PLPKNQPNTALFCTIL
TLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLV-DYLVPA-VYTEKLVVP
EGLSPSDPSKRGWYI-GFDTS----STWIPFACVIPALLVYILIFMESQISELIVDKPDR
GLKKGSGLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGESPR-I
VDVKEQRLSGFFVCLMIGLSVL--MAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRL
YFMPVKHYPPTSYVKRLRPWKLHLFTTIQVLCLVLL--WSVKS-SQFSLAFPFFLIMMVP
IRQ-NLTKLYKPEEMQALDGSEMKKNDDDE-------------------------PDFYE
QTNIPA------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|8394310|ref|NP_058744.1|	Rattus norvegicus
-------------------------------------------------MSSAPRR----
----PASGADSLHTPEPESLSPGT-PGFP-EQEE-----EDELRTLGVERFEEILQEAGS
RGGEEPGR--SYGEEDF---EYHRQSSHHIHH-----PLSTHLPPDARRRKTPQGPGRKP
RRRPGASPTGETPTI----------------EEGEEDEDEVGEAEGFRAPP-QQPSPASS
PSAVQFFLQEDEGT----DRKAERTSPSPPTQTPHQEAAPRASKGAQTGTLVEEM-----
----------VAVASGTAGGDDGGAAGRPLTKAQPGHRSYNLQERRRIGSMTGVE-QALL
PRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGST-QAAREGREP-----
GPTPRARPRAPHKPHEVFVELNELQLD-KNQEPQWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLL
KHSHPSDEKEFSF-P------------------RNISAGSLGSLLGHHHAQ---GTESD-
---------------------------------------------------PHVTEPLIG
GV---PE---------------------------------------TRLEVDRE-RE---
-----------------LPPPAPPAGITRSKS-KHELK----------------------
---------------------LLEKIPENAEATVVLVGCVEFLSRPTMAFVRLR-EAVEL
DAVLEVPVPVRFLFLLLGPSSANMDYH--EIGRSISTLMSDKQFHEAAYLADE----RDD
LLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQML----KKREEQGRLLPPGAGLEPK
-SAQDKALL----------QMVEVAGAAE-----DD--------PLRRTGRPFGGLIRDV
RRRYPHYLSDFRDALD-----PQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGV----
SELIMSTALQGVIFCLLGAQPLLVIGFSGPLLVFEEAFFSFCKSN-QLEYLVGRVWIGFW
LVLLALLMVALEGSFLVRFVS----RFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHGC
-------------------------------------SV-------SNDS----------
--EADSSSNNMTWA---ATTLAPDN----------SSASGQE---RPRGQPNTALLSLVL
MAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLV-DYSIED-TYTQKLSVP
SGFSVTAPDKRGWVINPLGEKT-PFPVWMMVASLLPAVLVFILIFMETQITTLIISKKER
MLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPK-I
QEVKEQRVTGLLVALLVGLSMV--IGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHL
LLMPPKHHPDVTYVKKVRTMRMHLFTALQLLCLALL--WAVMS-TAASLAFPFILILTVP
LRMVVLTRIFTEREMKCLDANEAEPVFDECEG-----------------------VDEYN
EMPMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|37221541|gb|AAQ89898.1|	Oreochromis mossambicus
------------------------------------------------------------
--------------------------------ME-----NNLTFEEGSDM----------
----------SYEDNGS---AF---------------PSPLMLNIPGQSDDFDLER----
-------------------------------GREEVEEDEP------------SPEPIVI
PTNSEAFLNLNTNA----T-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------TRGDAQAYVELNELEGNI------WQETGRWVGYEENFNHATGKWGPSHV
SYLTFTSLVHVRKAVSTGAIILDMNASNLSAVVEKMVDELLNKDVIRSSDHDDLMRVLLM
KRSQT----------------------------EGPVVTPFGDIQMQTFSVTKKRDSSD-
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------NVEASIVLSGELDFLQKPAVAFVRLS-DSVVM
ESVLESSIPIRFIFLLVGPGHSGINYS--ESGRAMGALLADWVFCLKAHLAQT----SKD
ITDAIADFMDCSIVIPPTEIQDTAMLEPVIDFQKKLLSDRLRSTDPRLAFGERVKALQPP
PGPK------------------------------ED--------PLARTGYPFGGMMKDI
KRRYRHYISDFTDALN-----PQVLAAVIFIYFAALSPAITFGGLLADKTEKMMGV----
SELMISTAAQGVFFCLIAAQPVLVIGFSGPLLVFEEAFFAFCKMQ-GIEYIVGRIWVGMW
LIVIVVLIVAMEGSFLVRYIS----RFTQEIFSILISLIFIYETFNKLFKIFATHPLILN
-YE------------------------------HLNDTL-------DNPF----------
--HPIIQEQVEIHPDGNVTVHKLET---------------------ERAYPNTALLSMCL
MFGCFFIAYFLRQFKNGHFLPGWLRRLIGDFGVPIAIFFMIAV-DISIED-AYTQKLVVP
KGIEVTNPNARGWFINPMGEKK-PFPGWMIGASCIPAVLVLILIFLESQITTLIVSKPER
KMVKGSGFHWDLLVLVTMGGIASIFGVPWLSAATVRSVTHANALTVMSK----GPKPE-I
EKVIEQRVSGMIVAIMIGVSIY--MEPILKMIPMTALFGIFLYMGITSLNGIQMWDRILL
LITPKKYHPPDAYATRVSTMRMHLFTLIQLVCLGVL--WAVKM-STFSLALPFVLILTVP
LRMFMTGRLFSAMEMKCLDADDAKVTFEEDE-----------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|51870487|emb|CAF32326.1|	Suberites domuncula
------------------------------------------------------------
-----------MNPPEKLSVTNYSRTDRHGNHE------VQMLDLPGSPQFPRRSTSPSP
PSMSTSSTPVREGHSPMFIEDGYSTRSEATGS-----DITTSSPGKTSRRNKGADLLNFV
TRKRTHS------------------------SSSSTDGGKSTGTRSSPSQS--SPSPGPI
NKAVRILMPSKSPT----SSKKSDVDTKVSTAIGHFSVAP--------------------
------------------------------------------------------------
---------------KDMSVLE------------------------------------RI
SKRAQHHSKRVRKPHEVFVELEELRLD-PSDELEWEETARWIKFEEDVEEGSGRWGRPHV
SALAFHSLVELRRGLEKGLVMLDVEGEDFPTIADQIVDTLVASGQLPEKQREPVLRILLK
KHKHSNDITLWEKLKQSAVDPDGRLHHIGEGLRRISHAHGLSELGGGSSSSVSKQDQSR-
-----------------------------------------------RKSLPDITLQETN
GSKEKELSNSSSSKRREFQRISSAPLLAESSDEIPSPSSSPPVHGILHIENGSNPRDMHI
SDKKVMFNIAGGSSEEFFPVVSPGSSGFVSQTGSTDVCNDTGTTRTQPLKKMTPKISKLP
LAPPERQINSSSLKRKMSVISLMNKIPDEAESLTVLVGGVKFLRKPVVAFVRLD-QSHLL
GDLTEVPVPLRFIYLLLGPEEGLCDYH--EVGRAMATLMSDSHFHDTAYCAVC----KED
FLDAMDKFLDDSIVLPPGDWDQELLL--PIMHERNEL----RRRKQHKVEENQRKVFS--
----------------------------------VD--------PLKHSRKPCGGMWNDV
KKLVKRYPSDLKDALH-----LQPIISIFFLYVAFLAPAIAFGGLMEEITKSQIGE----
TETLLATGLCGIVYGLFAVQPLTVLAFTGPLILFETVVYRFAVDELSISYIEWRSATGLW
LMVILMIASFAEISFLIKYFT----RFSEEIFTGIICLFFIFEACLSIYHIFERNPLCGI
DYPCGEASHMT-NTCQPIHE-------------DDNHSN-------ESYH----------
--DDHDSMVFMN-DSIDDVHAPVLP-----------------SGFRICNQPNTFLWSLML
CVFTFFIAFFLRKLRHGKFLGKQGRRLVSDFGMLTAILLMVAL-SYGLRHLIAVEKLTVP
PNYANSNIT-RGWFIHPFNGA---ISIGEGFGAIIPAFLLALLIFIESQLTVLLVSKPDH
KLEKGVG-TMCSLIVAILTGVCGLLGIPWVCGASVRSIQHLQALSVFTTKNPPGEKPK-L
LFIREQRVTTIVVHVLILLTPL--AYPVLALIPISVTLGVFFYLAYASLSGVQLTKRIKL
VITPSKHHPNVHYVRKVRTWKMHLYTFIQVVCIACL--FGLKN-SPAGMLYPVVIVALIP
LRWILGKFFFSHDEIEALDSEEDFPEEHDIHGGGG--------------------EFEEF
EAHVPY------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|119591183|gb|EAW70777.1|	Homo sapiens
---------------------------------------------MANGVIPPPGG----
----ASPLPQVRVPLEEPPLSPDV------EEED-----DDLGKTLAVSRFGDLISKPPA
WDPEKPSR--SYSERDF---EFHRHTSHHTHH-----PLSARLPPPHKLRRLPPTSARHT
RRKRKKEKTSAPPSEGTPPIQEEGG------AGVDEEEEEEEEEEGESEAEPVEPPPSGT
PQKAKFSIGSDEDDSPGLPGRAAVTKPLPSVGPHTDKSPQHSSRPCSELRDGDGTTDLAL
SSPRLLCCLPSSPSPRARASRLAGEKSRPWSPSA----SYDLRERLCPGSALGNP-GGPE
QQVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRTQGGRGSPSGLAP----I
LRRKKKKKKLDRRPHEVFVELNELMLD-RSQEPHWRETARWIKFEEDVEEETERWGKPHV
ASLSFRSLLELRRTIAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLL
KHSHPNDDKDSGFFP------------------RNPSSSSMNSVLGNHHPT----PSHG-
---------------------------------------------------PDGAVPTMA
DDLGEPA---------------------------------------PLWPHDPDAKE---
-----------------KPLHMPGGDGHRGKSLK--------------------------
---------------------LLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLN-EAVLL
ESVLEVPVPVRFLFVMLGPSHTSTDYH--ELGRSIATLMSDKLFHEAAYQADD----RQD
LLSAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELL----RKRREREQTKVEMTTRGGY
TAPGKELSL----------ELGGSEATPE-----DD--------PLLRTGSVFGGLVRDV
RRRYPHYPSDLRDALH-----SQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGV----
SELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQ-DLEYLTGRVWVGLW
LVVFVLALVAAEGSFLVRYIS----PFTQEIFAFLISLIFIYETFYKLYKVFTEHPLLPF
-Y-------------------------------PPEGAL-------EGSL----------
--AA--------GLEPNGSALPPTE--------------GPP---SPRNQPNTALLSLIL
MLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLV-DYSITD-TYTQKLTVP
TGLSVTSPDKRSWFIPPLGSAR-PFPPWMMVAAAVPALLVLILIFMETQITALIVSQKAR
RLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQ-I
QEVREQRVTGVLIASLVGLSIV--MGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLL
ILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALL--WVVKS-TAASLAFPFLLLLTVP
LRHCLLPRLFQDRELQALDSEDAEPNFDEDG------------------------QDEYN
ELHMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|108873031|gb|EAT37256.1|	Aedes aegypti
------------------------------------------------------------
-------------------------------MDH-----GGVDDEAPIDPRMKSRTFP--
------------EDPDY---EGHRAHTVYVGV-----HIPGSSRRHSQRRRHKHHQ----
-------------------------------QSKDSGDKSSASTES-------DRPVTPP
AQRVQFILGGEVGD----D-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------GNHESHPLFSEMEELVKE--GDEMAWKETARWVKFEEDVEEGGNRWSKPHV
ATLSLHSLFELRSLLLNGTVMLDMEAVSLEQIAELVCENMVNAGTLPIEARDKVIDALLK
RHKHQHEFGSKKT--------------------RLPLIRSLADIGKNHSSSKSKYCYIRR
-----------------------------------------SSTANSYPMHVVSSAPGMH
DDVGEAA---------------------------------PSPHTALLGGSSKDQRG---
-----------------HYLALPTGENLIQSPSSISMARNTSSGELQNGEHKSNTN----
---------------------FMRKIPPGAEASNILVGEVDFLDKTLAAFLRLN-NASVM
GDLTEVPVPTRFIFILLGPPGSHGSFH--EIGRAMATLMSDEIFHEVAYRAKK----REH
LLAGVDEFLDAVTVLPPGEWDPSIRIEPPAAIPSQEV----RKRPPEKNPKEEIDEEEEE
QRQRE-----------------------------ES--------GLSRTGRLFGGLVNDL
KRKKPFYLSDFKDGLS-----LQCVASWIFLYFACLSPIITFGGLLGSATGNNIAA----
MESLVSGFVCGIGYGLFSGQPLTILGSTGPVLVFETIVYDFCMRV-GWDYLTFRFWIGTW
VTIILVILVAIDASALVCYIT----RFTEENFACLIAFIFIYKAVENVLHIGKDYPLN--
-TAGSK---YD-CSCLPPGD-------------QPLNTD-------IVHE----------
------------WAQYDKKTCALLN----------GTLTGYDCA-KPEYISDVFLMSIIL
FIGTYIISVILKDFKNALFFPSNIRQVVSDFAVIIAIFSMSIL-DYLTN--VPTPKLEVP
REFKPTIPD-RGWLVQPFHEKN---PIWSPVLAVLPALLGTILIFMDQQITAVIINRKEH
KLKKGCGYHLDLFVLALLIQLCSLMGLPWFVAATVLSINHVNSLKQESETAAPGEKPQ-F
LGVREQRVTHILIFLTIGCSVL--LTPLLSHIPMPVLYGVFLYMGAASLKGLQFFDRLMI
MLMPIKYQPDYMFLRQVPIRRVHLFTLIQLACLIML--WVIKSFSSTSILFPLMLVVMIG
IRK-ALDFVFTRRELKILDDVMPEMTKRAHEDDLRQLED----------GEDSG-QHSAD
NLQLPLENGTLSCKPQINISEEVNRTTIW---KQVNNCNVLFTKKQPSNRKYHNQTNPPA
NLNSQNANEQTQQQPQLLSESKSKKSNEIDKRLSTMREEEETNSDDANHHRQLNHQKRTQ
KLKHEFWMNSSRGGNKTAGTKHNDTGYGERDASETQV
>gi|149639605|ref|XP_001512834.	Ornithorhynchus anatinus
------------------------------------------------------------
---MRSYGFLSFDASLAQLHVHARLQSGYSQCGHPDIAQDFGFPFSARRNDEEAVVDRGG
TRSILKT---HFEKEDL---EGHR--TLFIGV-----HVPLGGRKSHRRHRHRGHKHRKR
DRER---------------------------DSGLEDGRE-------------SPSFDTP
SQRVQFILGTEDDD----E-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------EHIPHDLFTELDEICWR-EGEDAEWRETARWLKFEEDVEDGGERWSKPYV
ATLSLHSLFELRSCILNGTVLLDMRANTLEEIADMILDQQVSSGQLSEDVRHRVHEALLK
QHHHQNQKKLSN---------------------RIPIVRSFADIGKKQSEPNSMDKNAG-
---------------------------------------------------QIVSPQSAP
ACV---------------------------------------------------------
-----------------ENKNDVSRENSTVDFSKVDLH----------------------
---------------------FMKKIPPGAEASNILVGELEFLDRAVVAFVRLS-PAVLL
TGMAEVPIPTRFLFILLGPLGKGQQYH--EIGRSIATLMTDEVFHDVAYKAKD----RND
LVSGIDEFLDQVTVLPPGEWDPTIRIEPPKNVPSQEK----RK----VPAVPNGTAAHGE
AEPHGGHS--------------------------GP--------ELQRTGRIFGGLILDI
KRKAPYFWSDFRDALS-----LQCLASFLFLYCACMSPVITFGGLLGEATEGRISA----
IESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKDY-GLSYLSLRASIGLW
TATLCIILVATDASSLVCYIT----RFTEEAFASLICIIFIYEALEKLFHLSESYPINMH
-NNLELLTHYS-CNCVEPHN-------------PSNNTL-------KAWS----------
--DHNVSASDISWENLTLSECKSLH----------GEYIGRACGHHGPYVPDVLFWSVIL
FFSTVTLSSMLKQFKTSRYFPTKVRSIVSDFAVFLTILSMVLI-DYAIG--IPSPKLQVP
SVFKPTRDD-RGWFVTPLGPN----PWWTVIAAIIPALLCTILIFMDQQITAVIINRKEH
KLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPK-F
LGIREQRVTGLMIFVLMGSSVF--MTSVLKFIPMPVLYGVFLYMGASSLKGIQLFDRLKL
FWMPAKHQPDFIYLRHVPLRKVHLFTIIQISCLGLL--WIIKV-SRAAIVFPMMVLALVF
VRK-LMDLFFTKRELSWLDDLMPESKKKKLEDAEKEEE------------QSMLAMEEEG
TVQLPLEG-----------HYRDDPSVIN---ISDEMSKTAVWRN---------------
------LLIPSENAKEKESSFPSKSSPS--------------------------------
-------------------------------------
>gi|114158636|ref|NP_001041496.	Canis lupus
------------------------------------------------------------
-------------------------------MDN-----QDSTMEKWQDDHEEGLED---
----------TLEQEEY---EDPYVPMVQVEE-----PVAYPTEPTATDEDTVTHPDTTP
RAG---------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------THEIYVELHELVMDEKNQELQWMEAAHWVRLEENLGEDGV-WGPPHL
SYLTFWSLLELQKAFVKGTVLLDLPETSLAGVANQLLDQFIYEEQIRPQDRDLLLRVLLL
KHSHAGD---------------------------------LEALGGVKPAVLMRSGDPS-
-------------------------------------------------------QPLLP
QQPSLET-----------------------------------------------------
-----------------QLFCKQGEGGTEDSPSR--------------------------
---------------------ILEKIPPDSEATLVLVGRAAFLERPVLGFVRLQ-MATEL
DAV-GLPLPVRFLFVLLGPEAPNTDYT--QLGRAVATLMSERVFRTDAYLAQT----KEE
LVRNLDCFLDCSLVLPPCEVPSEQALLSLVPVQKELL----RRRYLLSPAKPDPHFYKGL
-------------------DLNGGPGGPGES---DD--------PLQRTGLLFGGLVRDI
RRRYPLYLSDITDAFS-----PQVLAAVIFIYFAALSPAITFGGLLGEKTQNQMGV----
SELLISTAVQGILFSLLGAQPLLVVGFSGPLLVFEEAFFSFCTSN-NLEYIVGRVWIGFW
LVLLVVLMVAFEGSFLVRFIS----RYTQEIFSFLISLIFIYETFIKLIKIFQDHPLQRY
-Y----------------------------------------------------------
--------------DYNMTIIPKPQ--------------GPL--------PNTALLSLVL
MAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVMV-DFFIKD-TYTQKLSVP
RGLSVSNASARGWVIHPLGLYS-PFPIWMMFASVLPALLVFILIFLESQITTLIISKPER
KMVKGSGFHLDLLLVIGMGGVAALFGMPWLSATTVRSVTHANALTVMGKANIPGAAPQ-I
QEVKEQRISGLLVAVLVGVSIL--MGPILSLIPLAVLFGIFLYMGVTSLSGIQLFDRVLL
LFKPPKYHPDVPYVKRVKTWRMHLFTVIQIICLAVL--WTMKTFPTTSLTLPFILILTVP
LRRLLLPLIFRKLELQCLDADDAKPTFNEEEG-----------------------QDEYN
EVHMPV------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|47219833|emb|CAF97103.1|	Tetraodon nigroviridis
------------------------------------------------------------
-----------------------------------------VEDEAVLDRGAAFVKH---
----------ICDEEEV---EGHH--TVYIGV-----HVPKSYHRRRRHRRKSSHKEKRE
RTEHS--------------------------TEGHKSDADEANANI-------LKPLISP
AERIRFILGEEDDG----P-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------PPPQLFTELDELLAV-DGHEMEWKETARWIKFEEKVEKGGERWSKPHV
ATLSLHSLMELKMCIEKGTIMLDLEASTLPQVVETIIDSHIESGQLKADLREKVMYTLLR
KHRHQT---------------------------KKSNLRSLADIGKSVSSASRLFSSQE-
----------------------------------------------------NGSPTTAH
------------------------------------------------------------
-----------------RNLTSSSLGDFSDKPEKDQLKNK--------------------
---------------------FMKKLPRDAEASNVLVGEVDFLENPFVAFVRLQ-QAVML
GALTEVPVPTRFLFILLGPKGKAKSYH--EIGRSIATLMSDEVFHDIAYKAKN----RQD
LLAGIEEFLDEVIVLPPGEWDPDIRIEPPKSLPSSDK----RK---NMYAGVEVPQMNGD
TLHDAGA------------GAGGGGGGHQV----GE--------ELQHTGRFCGGLILDV
KRKLPFFASDFYDALH-----IQALSTILFIYLGTVTNAITFGGLLGDATENMQGV----
LESFVGTALTGAVFCLLAGQPLTILSSTGPVLVFERLLFNFSKDN-GFDYLEFRLWIGLW
SGLFCLVLVATDASFLVQYFT----RFTEEGFSALISFIFIYDAFKKMIKLGHHNLINAQ
-YDPNLITQYD-CRCTPVKIP-NSFVFFVIGNESLRSDL-------PPWS----------
--NSTDVAENATWATLSRDQCLKYG----------GSLVGEA----CRYVPDITLMSFIL
FFGTYACSMALKQFKTSRFFPTTVRKLISDFAIILTILVFCGV-DALVG--VNTPKLIVP
SEFKPTSPH-RGWFVPPFGGN----PWWVYLAAALPALLVTILIFMDQQITAVIVNRKEH
KLKKGAGYHLDLFWVAILMMICSFMGLPWYVAATVISIAHIDSLKMETQTSAPGEQPK-F
LGVREQRVTGIFVFILTGLSVF--MAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKL
LLMPAKHQPDLIYLRYVPQRRIHLFTFIQGLCLALL--WVLKS-TVAAIIFPVMILALVA
VRK-AMDYVFSQHDLSYLDDVIPEKDKKKKEDEKKKKQK----------KKGSIDSEIDF
S-DYPYHE--------------SIPTIKI---SMDMMEQEPMLRD---------------
---------K--------------------------------------------------
-------------------------------------
>gi|125840078|ref|XP_697323.2|	Danio rerio
------------------------------------------------------------
----------------------------MEEDSS-----EQMKPLLTTGNDDEAVVDQGK
TSSNIHT---NFEKEEL---ESHR--AVYVGV-----HVPLGRQSRRRHRHRGHKHHRKR
KDRC---------------------------SEREDGRD--------------SPTYDTP
SQRVQFILGTEDDD----E-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------EHIPHDLFTELDELCFR-DGLTCEWKETARWLKFEEDVEDGGERWSKPYV
ATLSLHSLFELRSCILNGTVMLDMRANSIEEIADMVLDNMVASEQLDESVREKVRDAVLK
RHHHQNEKKLSN---------------------RIPLVRSFADIGKKHSDPHLLERNGEG
LSTSRLSLLRRTSSTSTPPSSRRPSRESRYSRSSIILNQLLSSANSTPSTTPQNSPPTAH
RASPSLRPPGPSQQGPELLVARGDRDDIPEVVVFPPEEDVGDPLPAFYAVQDEKGGKNSD
FTTGLL-----------ASPQSAPGILENSKSSESRINGTGGSRENSTVDFSRVDMN---
---------------------FMKKIPPGAEASNVLVGEVDFLERPIIAFIRLS-PAVLL
TGLTEVPVPTRFLFLLLGPFGKGAQYH--EIGRSIATLMTDEIFHDVAYKAKD----RND
LLSGIDEFLDQVTVLPPGEWDPTIRIEPPKSVPSQEK----RK----MPSMPNGSTPQSD
VIKQEAHHA-------------------------GP--------ELQRTGRIFGGLVLDL
KRKAPFYWSDVRDAFS-----LQCLASILFLYCACMSPVITFGGLLGEATKNNISA----
IESLFGASLTGVAFSLFAGQPLTILGSTGPVLVFEKILFKFCSDY-GLSYLPLRTSIGLW
TAFLCLLLVATDASSLVCYIT----RFTEEAFAALICIIFIYEALEKLFQLGKMYPFNMH
-DDLNNLTFYT-CQCSPPSN-------------TTQKME-------QSWN----------
--QSGFTYDTINWTELNVQDCRDLH----------GEFVGPACGHNGPYIPDVLFWSVIL
FFTTFFLSSFLKQFKTKRYFPTKVRSSISDFAVFLTIMIMVLV-DYLVG--IPSPKLHVP
DRFEPTSKN-RGWLISPLGDN----PTWTLFAAAIPALLCTILIFMDQQITAVIINRKEH
KLKKGCGYHLDLLVVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPK-F
LGIREQRVTGLMIFVLMGLSVF--MTSILKFIPMPVLYGVFLYMGVSSLRGIQFFDRIKL
FGMPAKHQPDLIYLRYVPLWKVHIFTLVQLTCLVLL--WVIKV-SAAAVVFPMMVLALVF
VRK-LLDFCFTKRELSWLDDLMPESKKKKEDDKKKKAK-----------EEAQRMMEAEE
EIEIPFDGGDQLEIPEKTIQISTDPSVVN---ISDEMAKTAAWKGGNSSESATLLKASAS
EEKTACIKIRVEDEDEEDKRVDTETSL---------------------------------
-------------------------------------
>gi|91082251|ref|XP_972994.1|	Tribolium castaneum
------------------------------------------------------------
-----------------------------------------------MDKFSKVI-----
------------------------------------------------------------
-----------------------------------------------------SRTRTPP
SQRVQFILGEDVDD----E-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------KHESHPLFSEMEELVTE--GGDMEWKETARWIKFEENVEEGGNRWSKPHV
ATLSLHSLFELRSLILNGTVLLDLEATSMEQIADLVLDSMINSGLLANDKRDKVKEALLK
RHRHQHQRKDH----------------------VLPLIRSFAEMRNHSTSKSSVDKPRI-
--------------------------------------------------LKSASNVSMN
------------------------------------------------------------
-----------------RNYSTSDLGSMNGDLHQHNLH----------------------
---------------------FMRKIPPGAEASNILVGEVDFIDKTLSVFIRLN-SAVNL
GDLTEVPVPTRFLFVLLAPVSASTGYH--EIGRAMATLMSDEIFHEVAYRARN----TSH
LLAGIDEFLDAVTVLPPGEWDPAIRIEPPAAIPSQDV----RKRPPEKQPEEPDEEEEEQ
RIREES--------------------------------------GLARSGILFGGLINDV
KRKVPFYWSDFKDAFA-----TQCIASWIFLYFACLSPIITFGGLLAQATGGNMAA----
MESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFETIVYDFCMSV-GWDYLSFRFWIGTW
TAIILLVLVAIDASALVCYIT----RFTEENFATLIAFIFIYKAVENVALIGKNFPLN--
-TSGKRALDYN-CSC-SANQ-------------SVAMRD-------PYWG----------
-------N----WSIPSKNYCEITN----------GTLEGTGCE-TPPYVPDVFLMSILL
FLGTFLLSIELKDFKNALFFPSKVRQFISDFAVIIAILSMSLI-DLKVG--VPTPKLEVP
HDFKPTLPT-RGWLIPPFNGN----PVYSVFLAIPPALLGTILIFMDQQITSVIVNRKEH
KLKKKCGYHLDLFILAILIQVCSVMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQ-F
LGVREQRVTHILIFLTIGLSVF--LTPILGHIPMPVLFGVFLYMGIASLKGLQFFDRILI
MLMPNKYQPDYMFLRQVPIKRVHLFTLIQLTCLACL--WTIKSFSTTSILFPLMLVVMIG
IRK-SLDLIFTRRELKILDDIMPEMTKRNQMLKDDETDS----------EKGQLEIEPAG
NLKIPLANGNVMN---------IPLSAIN---ISEEVNKTSIWKQVNKNNTRPIEKEKKK
SPIGTGRFKKKKQSKRDEKQEKAKLEKRLSIMNEEEEDDGITIKVTDTSLHI--------
-------------------------------------
>gi|125979691|ref|XP_001353878.	Drosophila pseudoobscura
------------------------------------------------------------
---------------------------------------MSFSSASGRENNVRKLSFLGF
NTKKKSGGN-EDPDEVL---LDSEMEKVFAGT-----SARKDKFDVNTFQDNTQLPTASR
KKNSIRT------------------------NDLNIEEDSEYESQTEPLNN--AQNYDDI
PEDFPLVSERAGHG----DHSDNSAEEKHVQFGGAAGKKKIVITPP--------------
----------SLSYDDQPTDQSHERKRRKSRHQYYRQRKFSHQDSVEPKKTIEEN-GDAG
ARRISVQPEDTALEEADLNELRSHRSDDPRALRRHKIH--------HSSIKLRELPQITI
SPFTNKKPEVDHSPHEIFVQLDELTGV--GEDREWKETARWIKYEEDVEEGSDRWGKPHV
ASLSFHSLLNLRRCLETGVVLLDLNEKDLPAVAYRVVEQMVIEDLIDINDKPSVMRSLLL
RHRHVNEHQGVLPFT----------------KRKYNSYTSLQNLSGGTDDKKIK------
------------------------------------------------------------
------------------------------------------------------------
-----------------IMPAADIGGSKRSNELKIDMKDDMYSSSQEDLKKLQNDT----
---------------------ILRRIPAGAEATTVLVGAVEFLDQPTIAFVRLS-EGVMM
PTLTEVPVPVRFMFVLLGPRNFDLDYH--EVGRSISTLMANEHFHAIAYKADD----RKD
LLSAINEFLDDSIVLPPGNWDRHDLLPFEELKAKKDWI---RTRKIKALQVKRDSEMIKI
GKDEEKALLEK--------QSLGAMGMGPGDDDDDDGHKKKQPNPMEKTHRLWGGLRNDL
KRRMPMYKSDILDGLN-----TETLAATIFMYFACLSTAITFGGLVSDKTKSWIGI----
SETLISCSFVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQN-DFDFLSLRVYVGIW
LIIIALCVSAFEGSVYVRLLT----RFTQEIFSALITLIYIVETMMKLVSIYQQNPLLAD
-YNLPP---------------------------PTLVAH-------DQDQ----------
--NGSHFNMSATLLNATTTASPV----------------GTS--KLPTNQPNTALFCTIL
TLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLV-DYLVPS-VYTEKLVVP
AGLSPSAPQLRGWYI-GFNAT----STWVPFACVVPALLVYILIFMESQISELIVDKPER
GLKKGSGLHWDIVLLCLLNTFCGLFGMPWHCAATVRSVTHVSSVTIMSRTHAPGESPR-I
IDVKEQRLSGFFVCVMIGLSVL--MAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRL
YFMPVKHYPPTPYVKRVRPWKLHLFTTIQVLCLAVL--WTVKS-SRFSLAFPFFLIMMVP
IRQ-RLVALYKPEELQALDGQEAKNDEDE--------------------------PDFYE
QATIPA------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|115872189|ref|XP_791964.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
----------------------MSQNGRPATSKEKSDASLNLQVEELLKPPEKLPLTSSP
LDGEPETHFPQFGEKDY---ESHRSEDVLVHH-----QLD-PLPQRGSSKSLKDHDAQHQ
KIRTSH-------------------------SSKSIAEATEELITSIAEETIGDSVDGGE
KSTPKFIIGEDDGA----ETPVRSESQSDEKGLHEEANSKFNEK----------------
-------------------PGSHKHHRHHHHGKKQRNLSDDPNERLRQGSDVNLKMHDIS
IKIGGDDEEEGEMNPSIRETMAVHRLGDMSGGGRHHHSSRKHNVSSFVHVRGRTPSG-EK
NTSPRKKKEYDHRPHEVFVELDELYKE-EGHEMQWKEKARWIKYEEDVEEGAQRWGKPHV
ASLSFHSLVELRQYLEHATALFDLEETNLSNIFHRIVDSMINADQIKEENRADIMRALLL
KHKHVNDGGNSILRN-----------------FSTISLGSMDDKKGERHNEKHHHHPSG-
-------------------------------------------------ILKNLSSISLT
GHGQTKP---------------------------------EAEVRIPMINKDGKANTNGL
S----------------NENQNASSGAFKTTPSSTSLMKLAHKLDHKKIEG---------
---------------------IMRKIPQDAEATSALVGEVDFLETPAVSFVRLA-EGTIL
DNFSEVPIPVRFLFVMLVPTHSDINYH--ELGRSFSTLMSNDHFHETAYQAES----MRD
LLTAMNTFIDHTIVLPPGDWDRELLLPVLRMQHEKMK----KMRAETLAEEADGDMTVVD
ISTKQQPYSNL-----------------------PD--------PLKRTGKIFGGLINDV
RRRYPHYWSDIRDGIN-----FQCVAAFFFIFFAALSPAITFGGLLADKTENWIGV----
SETIVATAINGCIFALLSGQPLTIIGVTGPILVFEENLYSFCTDR-NIEYLPFRVWVGIW
LFVIITVMVAFEGSVLVQYFT----RFTEEIFAFLIGLIFVYEVFNKLYKTFKTHPLLED
-YCVVPGTD------------------------DPMNYT-------ELWT----------
--TSYTEYTDENGTVVYDLATPSYNMTGNMTGNMTGMGVCSSAKVVVAGQPNTALLSTIL
TLGTFFLAYFLRKFRQGRFLGRSARKMIGDFGIPISILVFVSV-DFLIKA-TYTQKLDVP
DGLKPSDVCKRGWFVNPLGINK-PLGIGLMFAAAIPALLAFILMYMETLITGLIINKKDN
KMKKGSGFHLDTFIIGCMAVMNGLLGLPLVWAATVRSVTHVGALSVFSKSHAPGEKPK-L
MKIIEQRVTALLIHIVIGASIA--ISPLLRQVPLAVLFGVFLYMGVTSLNGIQMVERASL
LFMPVKHHPDTRYVREVRTWRMHIFTIIQLGCLAIL--WIIKL-TPAALAFSFFLILLVP
IRS-QLKRIFTKQELDALDSDEVDANEDE--------------------------DDEYQ
TVHMPQ------------------------------------------------------
------------------------------------------------------------
-------------------------------------
>gi|82069164|sp|O13134|S4A4_AMB	Ambystoma tigrinum
------------------------------------------------------------
------------------------------MSSE--------------------------
----------KECLENM---LNGYAESGRVLS-----RTSLVINQAVNRSIF--------
-----------------------------------------------------TSTVSPA
AERIRFILGEEDDS----P-----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------APPQLFTELDELLAV-DGQEMEWKETARWIKFEEKVEQGGERWSKPHV
ATLSLHSLFELRTCIEKGTILLDLEATSLPQIVEIVINNQIELGLLKADMKENVTRTLLR
KHRHQT---------------------------KKSNLRSLADIGKTVSSASRLFSTPD-
----------------------------------------------------NGSPTMTH
------------------------------------------------------------
-----------------RNLTSTSLNDVSDKPDKEQLKNK--------------------
---------------------FMKKLPRDAEASNVLVGEVDFLESPFIAFVRLQ-QAVML
GSLTEVPVPTRFLFILLGPKGKAKSYH--EIGRSIATLMSDEVFHDIAYKAKN----RED
LIAGIDEFLDEVIVLPLGEWDPTIRIEPPKSLPSSDK----RK---NMYSGGDNLQMNGD
-APHDD----------------GGGGHGD-----SE--------ELQRTGRFCGGLIKDI
QRKAPFFASDFYDALS-----IQSLSAILFIYLGTVTNAITFGGLLGDATENMQGV----
LESFLGTAVSGAVFCLFGGQPLTILSSTGPVLVFERLLFNFSKDN-DFDYLEFRLWIGLW
SAFQCLILVATDASFLVKYFT----RFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSH
-FKVDYITQYS-CACFPPEP-ANSSWFNMTTAATTTQFL-------TNAS----------
--TDMAYNGTIDWSLLSKKECLKYG----------GLLVGSNCK----YVPDITLMSFIL
FLGTYTCSMALKKFKTSRYFPTTARKLISDFAIILSILIFCGL-DALLG--VDTPKLIVP
SEFKPTSPN-RGWFVPPFGGN----PWWVYLAAAIPALLVTILIFMDQQITGVIVNRKEH
KLKKGAGYHLDLFWVAILMVVCSFMALPWYVAATVISIAHIDSLKMETETSAPGEQPK-F
LGVREQRVTGTVVFLLTGLSVF--MAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKL
LLMPPKYQPDFIYLRHVPLRRVHLFTFLQVVCLAML--WILKS-TVAAIIFPVMILALVA
VRK-AMDYFFSQHDLSFLDDVIPEKDKKKKEDEKKKKK-----------KKGSIDSDVED
S-DCPYPE--------------KVPSIKI---PMDIMEKEPFLID---------------
--------SKPSDRENSPTFL-ERHTSC--------------------------------
-------------------------------------
>gi|149730869|ref|XP_001493175.	Equus caballus
-----------------------------------------MLTLEPGPTQRVLSYPRVD
GWM-DGWMPLALAALRLEAAAHVRPGGRETPRTE-----GAGCGAALASPPGQPVEAERA
EGGGGVEWCLDERGASI---WHFRQSPMDKGAFVEVWDSSGEIPAQCWSKTTPPQIGCIE
EGGGE--------------------------QLGEQQAVVGIKRMQILLTVSCTPSGSLP
LSHWGLLIVDTPCC----PMGTLYTLHKSPTSPSPPHELPDPNTKQSECRAECKTLKTLQ
RKVL------IPEALQNMEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLE
GHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDG---RESPSFDTPSQRVQ
FILGTEDDDEEHIPHDLFTELDEICWR-EGEDAEWRETARWLKFEEDVEDGGERWSKPYV
ATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDIRHRVHEALMK
QHHHQNQKKLTN---------------------RIPIVRSFADIGKKQSEPNSMDKNAG-
---------------------------------------------------QVVSPQSAP
ACVENKN------------------------------------------DVSRENST---
-----------------VDFSKGLGGQQKGHTSPCGMKQRHEKGPPHQQEREVDLH----
---------------------FMKKIPPGAEASNILVGELEFLDRTVVAFVRLS-PAVLL
QGLAEVPIPTRFLFILLGPLGKGQQYH--EIGRSIATLMTDEVFHDVAYKAKD----RND
LVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEK----RK----IPAVPNGTAAHGE
AEPHGGHS--------------------------GP--------ELQRTGRIFGGLILDI
KRKAPYFWSDFRDAFS-----LQCLASFLFLYCACMSPVITFGGLLGEATEGRISA----
IESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEY-GLSYLSLRASIGLW
TATLCIILVATDASSLVCYIT----RFTEEAFASLICIIFIYEALEKLFELSEAYPINMH
-NDLELLTQYS-CNCVEPHN-------------PSNDTL-------KEWR----------
--KSNISASDIIWENLTVSECKSLH----------GEYVGRACGHDHPYVPDVLFWSVIL
FFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLI-DYAIG--IPSPKLQVP
SVFKPTRDD-RGWFVTPLGPN----PWWTVIAAIIPALLCTILIFMDQQITAVIINRKEH
KLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPK-F
LGIREQRVTGLMIFILMGSSVF--MTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKL
FWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLL--WIIKV-SRAAIVFPMMVLALVF
VRK-LMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEE------------QSMLAMEDEG
TVQLPLEG-----------HYRDDPSVIN---ISDEMSKTALWRN---------------
------LLITADNSKDKESSFPSKSSPS--------------------------------
-------------------------------------
>gi|46409170|gb|AAS93742.1|	Drosophila melanogaster
------------------------------------------------------------
---------------------------------------MSFSSASGGENNVRKLSFLGF
NTKKKSGN--EDPDEVL---LDSEMDKVFAGN-----SARKDKFDVNTFQDNSQLPIGSR
KKNSIRT------------------------NDLNIEEDSEYESQTEPLNN--AQNYDDI
PEDFPLVSERAGHG----DHSDNSVDEKHVQFGGKKKIPP--------------------
----------SLSYDEQPTDQSHERKRRRSRHQYYRQRKFSHQDSVEPKNKLEEN-GDAG
ARRISVQPEDTALEEADLNELRSHRSDDPRALRRHKIH--------HSSIKLRELPQITI
SPFTNKKPEVDHSPHEIFVQLDELTGV--GEDREWKETARWIKYEEDVEEGSDRWGKPHV
ASLSFHSLLNLRRCLETGVVLLDLNEKDLPAVAYRVVEQMVIEDLIDINDKPSVMRSLLL
RHRHVNEHQGVLPFT----------------KRKYNSYTSLQNLSGTDDKKIK-------
------------------------------------------------------------
------------------------------------------------------------
-----------------IMPAAEIGGSKRSNELKIDMKDDMYSSSQEDLKKLQNDT----
---------------------ILKRIPAGAEATTVLVGAVEFLEQPTIAFVRLS-EGVLM
PTLTEVPVPVRFMFVLLGPRNFDLDYH--EVGRSISTLMANEHFHSIAYKADD----RKD
LLSAINEFLDDSIVLPPGNWDRHDLLPFEELKAKKDWI---RTRKIKALQVKRDSEMIKI
GKDEEKALLEKQTLGAIGFTIGGGDGGGDGDSDDDNGRKKKKPSPLEKTGRLWGGLRNDL
KRRMPMYKSDILDGLN-----TETLAATIFMYFACLSTAIIFGGLVSAKTNSWIGI----
SETLISCSLVGIVFHCLSCQPLVIIGTTGPLLLFDEALMVFCTQH-EFDFLSLRVYVGVW
LIIIALTVSAFEGSVYVRLLT----RFTQEIFSALITLIYIVETFMKLISIYRENPLLSD
-YNL-----------------------------PPPTLV-------AHEH----------
--ATNESLLNATASVTTDITQMVMN------ISTTAMPIGPP--PLPKNQPNTALFCTIL
TLATFVVAYYLKLFRNSHFLGRNARRALGDFGVPISIAIFVLV-DYLVPA-VYTEKLVVP
EGLSPSDPSKRGWYI-GFDTS----STWIPFACVIPALLVYILIFMESQISELIVDKPDR
GLKKGSGLHWDIVLLCLLNCACGIFGMPWHCAATVRSVTHVSSVTIMSRTHAPGESPR-I
VDVKEQRLSGFFVCLMIGLSVL--MAPLLRLIPMAVLFGVFLYMGVASMSGVQLFERIRL
YFMPVKHYPPTSYVKRLRPWRLHLFTTIQVLCLVLL--WSVKS-SQFSLAFPFFLIMMVP
IRQ-NLTKLYKPKEMQALDGSEMKKNDDDE-------------------------PDFYE
QTNIPA------------------------------------------------------
------------------------------------------------------------
-------------------------------------
