>gi|21666559|gb|AAM73758.1|AF39	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MASGRRGWDSSHEDD------
-------------------------------LPVYLARPGTTDQVPRQKYGGMFCNVEGA
FESKTLDFDALSVGQRGA-KTPRSSQ---GSGRGAGNRP-GVEGDT-RRGPGRE-ESRE-
PVPESPKP-------------AGVEIRSATGKEVLQNLGP-----KDK-----SDRLLIK
GGRIVNDDQSFYADIYMEDGLIKQIGD--NLIVPGG--VKTIEANGKMVMPGGIDVHTHF
QMP-YKGMTTVDD-----------------------------------------------
------------FFQGTKAALAG--GTTMIIDHVVPEP--ESSLTEAYEKWREWADGK-S
CCDYALHVDITHWNDSVKQEVQNLSK-EKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGE
LGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPL
YVTKVMSKSAADLISQARK---KG---NVV---FGEPITASLGIDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYINSLL--ASGDLQLSGSAHCTFSTAQKAIGKDN---FTAIPE
GTNGVEERMSVIWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDAVKIVSAKN
HQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKR---
-------I--KARRKMADLHAVPRGMYDGP--------VFD-----LTTT---PKGGTPA
GSTR-GSPTR-PNPP----------VRNLHQSGFSLSGTQVDEGV-RSASKRIVAPPGGR
SNITSLS
>gi|73951498|ref|XP_536244.2|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MADRRRAWNT--EDD------
-------------------------------LPVYLARPGSAAQTPRQKYGGMFAAVEGA
YENKTIDFDAYSVGRRGSARTPRSAGR---PDAVGLPGPGGSEDTASDGSELSG-SAVSS
PGEREERP-------------PALRIRSPGPRAKPLGRD------KAQ-----SDRLLIK
GGRIINDDQSFYADVYLEDGLIKQIGE--NLIVPGG--VKTIEANGRMVIPGGIDVNTYL
QKP-SQGMTAADD-----------------------------------------------
------------FFQGTRAALAG--GTTMIIDHVVPEP--GSSLLTSFEKWHEAADTK-S
CCDYSLHVDITSWYDGVREELEVLVQ-DKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKG
LGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPV
YITKVMSKSAADIITLARK---KG---PLV---FGEPIAASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYLTSLL--ACGDLQVTGSGHCPYSTAQKAVGKDN---FTLIPE
GVNGIEERMTVVWDKAVAT-----------------------------------------
--------GKMDENQFVAITSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKVKTITAKS
HKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKPFPEYLYQR---
-------V--RIRSKVSGLQGVPRGMYDGP--------VYE-----VPAT---PKYATPA
PSAK-SSPSKHQPPP----------IRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGR
SNITSLG
>gi|55846714|gb|AAV67361.1|	Macaca fascicularis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------DRLLIK
GGRIINDDQSLYADVYLEDGLIKQIGE--NLIVPGG--VKTIEANGRMVIPGGIDVNTYL
QKP-SQGMTAADD-----------------------------------------------
------------FFQGTRAALVG--GTTMIIDHVVPEP--GSSLLTSFEKWHEAADTK-S
CCDYSLHVDITSWYDGVREELDVLVQ-DKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKG
LGAVILVHAENGDLIAQEQKRILDMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPV
YITKVMSKSAADIIALARK---KG---PLV---FGEPIAASLGTDGTHXWSKNWAKAAAF
VTSPPLS---PDPTTPDYLTSLL--ACGDLQVTGSGHCPYSTAQKAVGKDN---FTLIPE
GVNGIEERMTVVWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKVKTITAKS
HKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKPFPEHLYQR---
-------V--KIRNKVFGLQGVSRGMYDGP--------VYE-----VPAT---PKYATPA
PSAK-SSPSKHQPPP----------IRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGR
-------
>gi|66472750|ref|NP_001018348.1	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------MSYQGKKNIP----------KIT-----SERLLIK
GGRIVNDDQSFYADIYMEDGVIKQIGD--NLIVPGG--VKTIEANGKMVIPGGIDIHTHL
QMP-FRGTTTADD-----------------------------------------------
------------FTQGTKAALAG--GTTMIVDHVIPEP--GCSLLEAFDRWSKWADEK-A
CCDYSLHVDITHWNDSVKQEVETLIK-EKGVNSFQVYMAFKDLYQMSNTELYEVFTFLGE
HGGIAQVHAENGEIIAEEQARMLEMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPL
YVTRVMSKSAADIISQARK---KG---NVV---FGEPITASLGTDGTHYWSKNWAKAASF
VTSPPLS---PDPTTPDYLNTLL--ASGDLSVVGSAHCTFSVAQKAIGKDD---FTQIPE
GVNGAEERMSIIWDKAVVT-----------------------------------------
--------GKMDENMFVAVTSTNAAKILNLYPRKGRIAVGSDSDLVIWDTDAVRTITAKT
HHSAAEYNVFEGMELRGAPMLVVCQGKIVLEDGNLHATSGTGRFIPCSPFPDFAYKR---
-------V--KARKQLAILKAVPRGMYDGP--------VSE-----FSPM---SRGGTPS
ASTR-TSPTK---VP----------VRNLHQSGFTLSGPE--EAPIRPAGRRIVVPPGGR
SNITSLS
>gi|47221239|emb|CAG13175.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------S--------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------SSA-----MTRILIK
GGKVVNDDCTQDADVYIENGIIQQVGK--ELMIPGG--AKVIDAAGKLVLPGGIDTSVHL
EES-FMNATTADD-----------------------------------------------
------------FYSGTKAALAG--GTTMVIGHVLPEK--NESLLEAFERYRLAADAK-S
CCDYALHVGVTWWGPKVRAEMEKLVR-EEGVNSFQMFMAYKDTFMLRDSELFQALQHCKD
IGAVARVHAENGELVAEGAKETLELGITGPEGIEISRPEELEAEATHRAVTIGNRANCPV
YLVNVSSTGAGDVVATAKM---QG---KVV---HGETTTAHCVLNGMQYYHQDWCYAAAH
VTAPPLR---LDPSTPNHLMSLL--GNDTLNVVASDHRPFTIKQKAMGKDD---FTKIPH
GLPGVQDRMSVIWEKGVVCVAPLFPPASQTFFPNLISETSAPGRGGSPDPVRCCLYPHGL
CWCDLQIGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPEGSKTISVDN
QVQGGDVNLYEGLRCHGVPLVTISRGSLVYENGMFTCAEGSGKFCPMRTFPDYLYKK---
-------M--VQRAKSQAVKPVDREPYTGE--------VVA-----VANS---GKRDV--
GSSELDTPTRPSTRH--------GGQRDLHESSFSLSGAQIDDNIPKRSSARILAPPGGR
SSG-IW-
>gi|118403680|ref|NP_001072314.	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------MERRSNWNK--EDD------
-------------------------------LPVYLARPGTTAQTPRVKYGGMFANVEGA
YENKTIDFDAYSVGKKGT-RTPRSSSR---PDM----DGDNFSETASDVSEISG-SVISS
PGEREDRT-------------PGIEIKYSGGKELLQGQH------NGK-----SDRLLIK
GGRIINDDQSFYADVYFEDGLIKQIGE--NLIVPGG--VKTIEANGRMVIPGGIDVNTYL
QKP-YLGMSTLDD-----------------------------------------------
------------FYQGTKAAVAG--GTTMIIDHVVPDP--GSNLLSCFEKWHEVADTK-S
CCDYSLHVDITNWYDGIREELDILIQ-DKGVNSFQVYMAYKDLYQMTDSQLYEIFMYLKG
LGAVVMVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIASRINCPV
YITKVMSKSASDVIAQARK---KG---ALV---FGEPITASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYLNSLL--ACGDLQVTGSGHCSYSTAQKAIGKDN---FTLIPE
GVNGIEERMSIVWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKIKAVSAKT
HKSAVEYNIFEGMECRGAPLMVISQGKIVYEDGNLHVNQGMGRFIPRKPFPEYIYQR---
-------I--KIRNKVAGLEPVSRGMYDGP--------VYE-----VPAP---PKYATPA
PSAK-SSPSKPQPPP----------VRNLHQSNFSLSGAQKDDTNPRRTGHRIVNPPGGR
SNITSLG
>gi|148705577|gb|EDL37524.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MAERRRAWNT--EDD------
-------------------------------LPVYLARPGSAAQTPRQKYGGMFAAVEGA
YENKTIDFDAYSVGRRGSARTPRSAGR---PDAVGLPCPGGSEDTASDVSEPSG-SAVSS
PGDRDDRP-------------PALRIRCPAPRDLPLGRD------NGQ-----SDRLLIR
GGRIINDDQSFYADVYLEDGLIKQIGE--NLIVPGG--VKTIEANGRMVIPGGIDVNTYL
QKP-SQGMTSADDFFQGTKAALAGGTTMIRENLIVPGGVKTIEANGRMVIPGGIDVNTYL
QKPSQGMTSADDFFQGTKAALAG--GTTMIIDHVVPEP--GSSLLTSFEKWHEAADTK-S
CCDYSLHVDITSWYDGVREELEVLVQ-DKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKG
LGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPV
YITKVMSKSAADIIALARK---KGRWCPLV---FGEPIAASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYLTSLL--ACGDLQVTGSGHCPYSTAQKAVGKDN---FTLIPE
GVNGIEERMTVVWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKS
HKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQR---
-------V--RIRSKVFGLHSVSRGMYDGP--------VYE-----VPAT---PKHAAPA
PSAK-SSPSKHQPPP----------IRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGR
SNITSLG
>gi|91092752|ref|XP_973416.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------MSTPVKKVPIHL-------QSA-----QNRLLIK
HGKVVNEDDITEDDIYIEDGVIKQLGR--NLIIPGG--TRVIDARGKYVLPGGIDPHTHF
EME-FMGAKSVDD-----------------------------------------------
------------FYQGTKAAVAG--GTTMIIDFVMPKK--GESILDAFYEYRQKGDDK-V
CCDYGLHVALTHWNEQVRREMEVLCK-EHGVNSFKVFMAYG--FMLNDSELYSVFETCQK
LGAVAQVHAENGAIIAKNVERLLAKGITGPEGHEMSRPEEVEAEAVNRACVIAKQVDCPL
YIVHVMSKSAGLALKQACE---RG---TRV---YGETLVAALASDGSHYKHECFQHSAGH
ILSPPLR---PDPTTPQFLMNLL--AQDVLQVTGSDNCTFNKSQKEMGKND---FSKIPN
GVNGVEDRMSVIWEKGVQS-----------------------------------------
--------GMIDPCRFVAITSTNAAKIFNIYPRKGCIAVGSDADLVIWDPTKTRTISAST
HHQAVDFNIFEGMVCHGVPEFVIVNGRVCVDDGQLRVVQGHGHFVETPVYAPFVYDP---
-------------EKIADLKPVRNGTHDDNLSEHVHKVVFD-----FVTI---EDKACPT
P----TLPDSAVSTP-SVRGPRPEGQRNIQDSTFSIS---EDLDVDRKSCIRVRNPPGGK
SSG-FW-
>gi|148229451|ref|NP_001079502.	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MAERSSREKVNGESN------
---------------------------------NFFSTLGSGSPKPRQKYGGMFCNVEGA
FENKTINFDSLSVGKKNGRKMEMNKSS------------PESDSGSDCGSLSSL------
-----DRQ-------------ATDNVEIQGSTKLNTGDA------TPQ-----SDRLLIK
GGKIVNDDQSFPADIYIEDGLIKQIGE--NLIVPGG--VKTIDAHGLLVIPGGIDVHTRL
QMP-VMGMTSADD-----------------------------------------------
------------FFQGTKAALAG--GTTMIIDHVFPNS--GMNLVQAYDQWREWADGS-V
CCDYSLHVDITHWHESLKEELEALVK-DKGVNSFLVYMAYKEQYQCTDAEMYEIFSIIRE
LGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAFRAITIAKQANCPL
YITKVMSRGAADVIAQAKR---KG---IVV---YGETLPASIGTDGTHYWSKNWAKAAAY
VTSPPIS---PDPSTPDHLTSLL--SCGDLQVTGSAHCTFTTAQKAVGKDN---FTLIPE
GTNGIEERMTIIWDKCVTS-----------------------------------------
--------GKMDENAFVAVTSTNAAKLFNLYPRKGRIAAGSDADLIIWNPKTAKIISAKT
HNVAVELNIFEGMECYGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKR---
-------I--KARNRLAEIRGVPRGLYDGP--------VHD-----VTIS---SKSAAPT
PASRITCPGKIQIGP----------ARNLHHSGFSLSGTQEDDHIPRRTTQKIVAPPGGR
SNITSLS
>gi|157116503|ref|XP_001658524.	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------MHLWNN-----------
------------------------------------------------------------
--AKSLSF----------------------------------------------------
-----RKL-------------SSKNLIAMDGTPAPSG--------ESA-----QNRLYIK
RGHVVNHDGMQQADIYIEDGTIRYVGSGADFVVPGG--CRTIDATGKMIIPGGIDPHTHF
QLE-FGGTVAVDD-----------------------------------------------
------------FYQGTKAAVAG--GTTTVIDFVIPKK--GESLLEAYDTWRARADTK-V
VCDYGLHVAITWWSKSVRDEMKILCQ-ERGVNSFKCFMAYKGLFQVTDSELYEIFETCKE
LGAVAQVHAENGDVIAKNVQKLLAAGVTGPEGHELSRTEEVEAEAVNRACVIAHQTKTPL
YVTRVTSKLAAEQVSQARR---RG---LLV---YGETLASSLGCSLTNVKPNTLAY---Y
VTSPPIR---PDPETPRHLMKFL--ALDDLQTTGSDNCTFNKNQKELGLGD---FTKIPN
GVNGVEDRMSVVWEKGVQT-----------------------------------------
--------GLIDPQRFVAITSTNAAKIFNIYPRKGRIAPGSDADVLIWDPQAVRTISAST
HHQACDFNIFEGMKCHGVPEYVIVHGRVCVENGLLRVAEGQGSFLETPINPPFVYDA---
-------LN-GITNRNGDDKEARNGLQNLDLNQ-----KHD-----VPDSYALPDKYVPG
PALSIISGDSAVSTPHSARGHRPDGTKDMQQSTFSIS--EEMDTSGNRACIRVKNPPGGK
SSG-FW-
>gi|115969215|ref|XP_001192377.	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
-------------------MFETVSGGSNSLKFTEDTPEERERRRRVQQEMADAANSPRR
VPKGKLGMTTVEMFEGTHDSVQFPSERGEGLIKPTLEQLEDSPHRVKRPGGSMFKSVDGG
--GNSLQFDSVRRGISVDSSASSSPRRTPCDSVFTVVDNPDYSADAETGDPSALFKKSPS
KSSGRGIA-------------CGGGPTSWTGGPIVLGADDETDDDGTA-----QNRLLIK
GGKVVNSDTSFYADVYMEDGIIRQVGK--DLITPGG--AKVLDAKGKLIIPGGIDTHTHM
QLP-FMGTCAIDD-----------------------------------------------
------------FYQGTKAALAG--GTTMIIDHCLPTR--GQSLVEAYDQWRAWADPK-V
CCDYSLHVGITWWSESVQKELSVIAE-EKGINSFKMFMAYKDVFMLQDFELYRAFAALKE
LGALPLVHAENGDIIAENTKKLLELGINGPEGHLQSRPEDVEAEAVNRAICIANQVNSPL
YVVHVMSKSAADEISKARR---QG---KLVNNLFCEMLPLIFPTHGDELWGVEMVHTVCH
ELNPESETKLPDPFKTTYLITLLYFHSNDLQLTGTDHCTFKSEQKAMGKDD---FTKIPN
GVNGVEDRMSVIWEKGVET-----------------------------------------
--------GKLDECRFVAVTSTNAAKIFNMYPRKGVIQVGSDADVVIWDPMATRVISKET
HHQAVDFNIFEGMECHGVPLTVISNGRVVLEDGEV-------------------------
-------I--FGEPIAAGLGTDGTNYFHHE--------WLH------------AAAHVMG
PPLR-PDPTT----P-----------------GYLMD-----------------------
----LLA
>gi|156555189|ref|XP_001603682.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------MRGTSKIQSCVNEFIHG------
-------------------------------IPDERGGKYLWCYKIRITLAADQSLLKTI
DDNKDDDDDDDDDDDDDGGITIGEPVTHLIFHIGKNKRLANCSRETQIEAGKRTFSPAA-
-----RDV-------------SSLSHSPRPMRALPLLLL------QSA-----QNRLLIK
NGKVVNEDGIFDADVYVEDGIIKQLGR--NLIIPGG--TRTIDARGKYVMPGGIDPHTHF
EFELFQGTTSVDD-----------------------------------------------
------------FYQGTKAAVAG--GTTMIIDFAIPKP--DEGLLEAYERYRMIADEK-V
CCDYALHVGVTSWTAKTREEMATLVQ-QHGVNSFKFFMAYRDLFMLRDPELIEAFKVCKS
LGAVAMVHAENGDLIYENTKKLLAAGVTGPEGHEMSRPEEVEAEAVNRACVIANQVACPL
YVVHVMSRSAAEEVEKARR---RG---VCV---WGETLAAALGADGSNYQHRCWRHAAGH
VLSPPLR---PDPDTPLELMKKL--NSDGLQVTGSDNCTFNADQKAIGKDD---FSKIPN
GVNGVEDRMSVVWEKGVHA-----------------------------------------
--------GIMDPSRFVAVTSTNAAKIFNLYPKKGVIAVGSDADIVVWDPSRKRTISAQT
HHQAVDFNIFEGMEVHGVPEYVVVGGRVCVDECDVKAVHGFGKFVESLPYPGYVYEA---
-------V--EEREK--QPRGVARSEADAR--------KFAEEDAAFPAR---PNTIPCT
P----TLPNSAVATP-SVKGPRMEGQRNLQDSTFSIS---EDSKEASRSCIRVNNPPGGR
SAGGFW-
>gi|56754790|gb|AAW25580.1|	Schistosoma japonicum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MHL-------QSS-----QNRLLIK
GGKVVNDDRMFTADIYIEDGVIRQVGN--QLSIPGG--VRIIDASGKMVIPGGIDPHTCF
ESS-CFGLNTSDD-----------------------------------------------
------------FYSGTKAALAG--GTTTIINCIMPT---QSSLLDMYDKCRQAADAK-A
CCDYAFHFVLPQYDPKVSKEMELLVK-EKGVNSFRVFLSNTNNMLIDDGDFFEVAKRCRD
LGAILQVHAENGKLVKILESKIYNDGITGPEGCLYSHPEMAEVEATHRALSLAESAVCPL
YILQVTSTKAAHQISKARW---RG---NAV---VGETLAAALGADGTHYKHNCWRHAAGY
VLSPPLR---ANPCTPEELMRYV--STGVLECTASGHCTFKADQKALGKDD---FRKIPP
GVNGVEDRMSIVWEKGVMS-----------------------------------------
--------GFMDPCKFVAVTSTNAAKVFSLYPHKGRIDVGSDADLVIWDGDMTRTISVKS
NHENVDFNIFEGLHCHGVPLVVITAGRVVLEDGELRVTQGAGRFVPASSFSPYIFER---
-------T--KRLALMRSVKPVVRDPYSGP--------VSA-----EFIV---PTAGIVT
NGTE-KVPVGSDGDGLRPRSPTRSGGRNMQESSFSLSGAQYDDSRPLRTGIRTKQPPGGA
SNA-LW-
>gi|125777246|ref|XP_001359545.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MSTSPKPVKKVPIHL-------QSA-----ANRVYIK
NGEIVNHDKSFKADVYIEDGIIKFVGPPSEITIPGG--VRTIDASGLLIIPGGIDPHTHM
QLP-FGGAVAVDD-----------------------------------------------
------------FYSGTKAAVAG--GTTMIIDFVLPNK--HESMIEAYDKWRSWADPK-V
CCDYGLHVGITWWSKSVSEELGILCK-ELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRQ
LNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQMKTPL
FVSGLTSKSSAELVGRARR---SG---YCV---FGETLASSIGRSMS---GVSKAERIYY
ITSPPIR---ESAETPRQLMKSL--AYDDLQLTGSDNCTFNKEHKAKGKGD---FTKIPN
GVNGVEDRMSLVWEKGVQA-----------------------------------------
--------GLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDT
HHQACDFNIFEGMTVHGVCEFVLVRGRICAERGQVRVAEGFGRFIPTPVRPPFVYDI---
-------IEGKVQSAVQEDHPEERQNGGGNSVAK----KFAELDIQIPIQE--PISAMLA
GNLAMPAEGSMCSTP-SVRG-RVDGKHDMQQSSFSIS--EELDRGGVRACIKVKNPPGGK
SSG-FW-
>gi|149632453|ref|XP_001512357.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------MAVPVAGSPTVICIRHGS
-----------------P-NSPESSP------------P---------------------
PESRKKWS-------------NGRNVPSPSSKSYCNHISS-----RN-------DRLLIK
GGRIVNDDQSFYADIYMEDGLIKQIGD--NLIVPGG--VKTIEANGKMVIPGGIDVHTHL
QMP-YRGMTTVDD-----------------------------------------------
------------FFQGTKAALAG--GTTMIIDHVIPEP--ESSLAEAYEKWREWADGK-T
CCDYALHVDITNWNDRTKQEVQTLIK-EKGVNSFMVYMAYKDLYQMSNTELYEIFSCLGE
LGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPL
YITKVMSKSAADLISQARK---RG---NVV---FGEPITASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYISSLL--ASGDLQISGSAHCTFSTAQKAIGKDN---FTAIPE
GTNGIEERMSVIWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRVSVGSDSDLVIWDPDAVKIVSAKS
HQSAAEYNIFEGMELRGAPVVVISQGKIMLEDGNLHVTQGTGRFIPCSPFSDYIYKR---
-------I--RARREMAEMHAVPRGMYDGP--------VFD-----LTTT---PKGGTPA
VSTK-GSPTR-QTPP----------VRNLHQSGFSLSGTQVDEGV-RAASKRIVAPPGGR
SNITSLS
>gi|28194049|gb|AAO33382.1|AF46	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MSTSPKPVKKVPIHL-------QSA-----QNRVYIK
NGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGG--VRTIDASGLMIIPGGIDPHTHM
QLP-FGGAVAVDD-----------------------------------------------
------------FYHGTKAAVAG--GTTMIIDFVLPNK--HESMIEAYDKWRSWADPK-V
CCDYGLHVGITWWSKSVSEEIGILCK-ELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRH
LNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPL
YVVHVMSKSAGIELARARHR-YRG---RYI---MGETLAAALGTDATCCQHLGFDAEAAH
VLSPPLR---PDKTTPEFLMKLL--ANDDLQLTGSDNCTFNKEHKALGKGD---FTKIPN
GVNGVEDRMSLVWEKGVHA-----------------------------------------
--------GLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDT
HHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDI---
-------IEGKVQSQPEEQHEEKQNGSMAK--------RFAELDIQIPVQE--PISAMLA
GNLAMPAEGSLCSTP-SVRG-RVDGKRDLQESSFSIS--EELDRSGVRACIKVKNPPGGK
SSG-FW-
>gi|68354162|ref|XP_688378.1|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MSDYRRQWNR--EDE------
-------------------------------LPVYLAKP-ISAGNQRQKSHGMFSSVEGA
YDSKTIDFEQYAVGRS---RTSRSSSR------------ERIVDGDFEAYEISGRSIISS
PRERGDGR-------------PGVEITDQTEKESLNERN------NDE-----SERLLIK
GGRVVNDDQSLYADVYVEDGIIKQVGE--NLIVPGG--VKVIEANGCMVIPGGIDVNTCL
HKP-YLGTPPVDD-----------------------------------------------
------------FYQGTKAALAG--GTTMIIDHVTPQP--GDGLLEAFEKWQEAADKK-S
CCDYSLHVDIPHWHEGVKEELEQLVQ-EKGINSFQVYMAYKGLYQMPDSQLYEAFSFLKE
LGAVVLVHAENGDLIAQEQSKILGMGIIGPEGHPLSRPEELEAEAVFRAITIGNRVNCPV
YITKVMSKSAAETVAIARK---KG---SVV---FGEPITASLATDGSHYWSKNWAKAAAY
VTSPPLS---PDPTTPEHLHSLL--ACGDLQVVGSGHCAYSTSQKAIGKDN---FTLIPE
GTNGVEERMGFVWDKAVAM-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPDKIKTITAKS
QQSALEYNIFEGMDCRGGPLHVVSQGRVVFEEGKLQVQQGTGRFISRKPFPDFAYQR---
-------I--KYRNKIMNMQGVSRGMYDGP--------VYD-----VPAT---PKYITPA
PSAK-TSPTTHQPPP----------IRNLHQSNFSLSGSQIDDNIPRRSGHRIVAPPGGR
SNITSLG
>gi|126291169|ref|XP_001378663.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MASGRRGWDSSHEDD------
-------------------------------LPVYLARPGTTDQIPRQKYGGMFCNVEGA
FESKTLDFDALSVGQRGA-KTPRSSQGGGGGGGGGGNRPVAADLDTPRRSLARE-DCRDY
PA---PAI-------------SGVEIRSASGKEVLQNLDP-----KDK-----SDRLLIK
GGRIVNDDQSFYADIYMEDGLIKQIGD--NLIVPGG--VKTIEAHGKMVIPGGIDVHTHF
QMP-YKGMTTVDD-----------------------------------------------
------------FFQGTKAALAG--GTTMIIDHVVPDP--ESSLIEAFEKWREWADGK-T
CCDYSLNVDITHWNDRVKQEVQNLIK-DKGVNSFMVYMAYKDLYQVSNTELYEIFTCLAE
LGAIAQVHAENGDIIAQEQTRMLEIGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPL
YITKVMSKSAADLISQARK---KG---NVV---FGEPITASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYINSLL--ASGDLQIAGSAHCTFSTAQKAIGKDN---FTAIPE
GTNGVEERMSVIWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNASKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKN
HQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCNPFSDFVYKR---
-------I--KARRKMAEMHAVPRGMYDGP--------VFD-----LTTT---PKGGTPA
GSTR-GSPTR-QTPP----------VRNLHQSGFSLSGTQVDEGV-RSASKRIVAPPGGR
SNITSLS
>gi|157017699|gb|EAA08415.2|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------MASPTPAPVKKVPIHL-------QSA-----QNRLYIK
RGHVVNHDGMQQADVYIEDGTVRYVGSGADFVVPGG--CRTIDATGKLVMPGGIDPHTHF
QLE-FGGTVSVDD-----------------------------------------------
------------FYKGTKAAVAG--GTTTILDFVLPKK--GESLLEAYDAWRARADPK-V
VCDYGLHVGITWWSKSVRDEMRILCQ-ERGVNSFKCFMAYKGLYQLNDSELYEVFETCKE
LGAVAMVHAENGDIIAKNVTKLLTEGVTGPEGHELSRSEEVEAEATNRACVIAHQTKAPL
YVTRVTSKLAAEQLSQAKR---RG---LVV---YGETLASSLGCTLTSVKPNQLVY---Y
TTSPPIR---KDPETPRHLVKFL--ALDDLQTTGSDNCTFNRNQKELGLKD---FSKIPN
GVNGVEDRMSVVWEKGVQT-----------------------------------------
--------GLIDPQRFVAITSTNAAKIFNLYPRKGRIAPGSDADLLIWDPKAVRTISAST
HHQACDFNIFEGMKCHGVPEFVIVRGRVCVEYDLIRVAEGQGSFLETPVYPSFVYDALNG
VARPEEGL--EEKHARNGIQGLELNSKSGH--------EVD-----IPDTYALPEKYIPG
PALSVISGDSQLSTPHSARGHRPDGQKNMQESTFSIS--EELDKSEARSCIRVRAPPGGK
SSG-FW-
>gi|149726762|ref|XP_001501814.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
----------------MEMSWIMGKVSEGLNDMAFTMETTPRGRSGWDSSHEDD------
-------------------------------LPVYLARPGTTDQVPRQKYGGMFCNVEGA
FESKTLDFDALSVGQRGA-KTPRSSQ---GSGRGSGSRA-GVEGDTPRRGQGRE-ESRE-
PVPASPAP-------------AGVEIRSATGKEVLQNLGP-----KDK-----SDRLLIK
GGRIVNDDQSFYADIYMEDGLIKQIGD--NLIVPGG--VKTVEANGKMVIPGGIDVHTHF
QMP-YKGMTTVDD-----------------------------------------------
------------FFQGTKAALAG--GTTMIIDHVVPEP--ESSLTEAYEKWREWADGK-S
CCDYALHVDVTHWNDSVKQEVQSLIK-DKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGE
LGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPL
YVTKVMSKSAADLISQARK---KG---NVV---FGEPITASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYINSLL--ASGDLQLSGSAHCTFSTAQKAIGKDN---FTAIPE
GTNGVEERMSVIWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKN
HQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGTGRFIPCSPFSDYVYKR---
-------I--KARRKMADLHAVPRGMYDGP--------VFD-----LTTT---PKGGTPA
GSTR-GSPTR-PTPP----------VRNLHQSGFSLSGTQVDEGV-RSASKRIVAPPGGR
SNITSLS
>gi|62422571|ref|NP_001014809.1	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MADRRRAWNT--EDD------
-------------------------------LPVYLARPGSAAQTPRQKYGGMFAAVEGA
YENKTIDFDAYSVGRRGSARTPRSAGR---PDAVGLPGPGGSEDTASDVSEPSG-SAVSS
PGERDERP-------------PTLRIRRPAPRDLPLGRD------NGQ-----SDRLLIK
GGRIINDDQSLYADVYLEDGLIKQIGE--NLIVPGG--VKTIEANGRMVIPGGIDVNTYL
QKP-SQGMTAADD-----------------------------------------------
------------FFQGTRAALVG--GTTMIIDHVVPEP--GSSLLTSFEKWHEAADTK-S
CCDYSLHVDITSWYDGVREELEVLVQ-DKGVNSFQVYMAYKDVYQMSDSQLYEAFTFLKG
LGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPV
YITKVMSKSAADIIALARK---KG---PLV---FGEPIAASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYLTSLL--ACGDLQVTGSGHCPYSTAQKAVGKDN---FTLIPE
GVNGIEERMTVVWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKS
HKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQR---
-------V--KIRNKVFGLQGVSRGMYDGP--------VYE-----VPAT---PKYATPA
PSAK-SSPSKHQPPP----------IRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGR
SNITSLG
>gi|33340019|gb|AAQ14485.1|AF30	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MAERKRNWNK--EDD------
-------------------------------LPVYLARPGTTAQTPRQKYGGMFASVEGA
YENKTIDFDAYSVGKKGS-RTPRSGSRHDMLDGGD-----NYSETASDISEVSG-SVISS
PGEREDKT-------------PGVEIRFPLGKELLQGPD------NGQ-----SDRLLIK
GGRIINDDHSFYADLYLEDGLIKQIGE--NLIVPGG--VKTIEANGRMVIPGGIDVNTYL
QKP-YQGMTTVDD-----------------------------------------------
------------FYQGTKAAVAG--GTTMIIDHVLPEP--GSSLLTSFEKWHEAADTK-S
CCDYSLHVDITSWYDGIREELEVLVQ-DKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKS
LGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIASRINCPV
YITKVMSKSAADIIALARK---RG---PLV---FGEPITASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDHLNSLL--ACGDLQVTGSGHCPYSTAQKAIGKDN---FTMIPE
GVNGIEERMTVVWDKAVAT-----------------------------------------
--------GKMDESQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKVKTITAKS
HKSAVEYNIFEGMECHGAPLVVISQGKIVYEDGNLHVNKGMGRFIPRKPFPEYLYQR---
-------I--KIRNKVGGLQGVSRGMYDGP--------VYE-----IPAT---PKYATPA
PSTK-SSPAKNQPPP----------IRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGR
SNITSLG
>gi|119894195|ref|XP_580336.3|	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MRRFVPGKSTRSCDVPGAPRP
GPHEGPHTCGAAHGLRLRIRSPSLAFKRALKKPDLPNRESEAGAQPRAWKRFLVRGERGE
SGSAPRRREELSVCSP---LLPPSSRPPRGAGRCWQPELRRRASGPSSRGQPSSVPLVSG
PGPLSPRPREAGPRDSRTERKPAPQSPPAGPRAPEVGRGAMSYQGKKSIPHITSDRLLIK
GGRIINDDQSFYADVYLEDGLIKQIGE--NLIVPGG--VKTIEANGRMVIPGGIDVNTYL
QKP-SQGMTAADD-----------------------------------------------
------------FFQGTKAALAG--GTTMIIDHVVPEP--GSSLLTSFEKWHEAADTK-S
CCDYSLHVDITSWYDGVREELEVLVQ-DKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKG
LGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPV
YITKVMSKSAADIITLARK---KG---PLV---FGEPIAASLGTDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYLTSLL--ACGDLQVTGSSHCPYSTAQKAVGKDN---FTLIPE
GVNGIEERMTVVWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKVKTITAKS
HKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKPFPEYLYQR---
-------I--RIRNKVSGLQGVPRGMYDGP--------VYE-----VPAT---PKYATPA
PSVK-SSPSKHQPPP----------IRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGR
SNITSLG
>gi|109079206|ref|XP_001102251.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MASGRRGWDSSHEDD------
-------------------------------LPVYLARPGTTDQVPRQKYGGMFCNVEGA
FESKTLDFDALSVGQRGA-KTPRSGQ---GSDRGSGSRP-GTEGDTPRRGQGRE-ESRE-
PAPASPAP-------------SGVEIRSATGKEVLQNLGP-----KDK-----SDRLLIK
GGRIVNDDQSFYADIYMEDGLIKQIGD--NLIVPGG--VKTIEANGKMVIPGGIDVHTHF
QMP-YKGMTTVDD-----------------------------------------------
------------FFQGTKAALAG--GTTMIIDHVVPEP--ESSLTEAYEKWREWADGK-S
CCDYALHVDITHWNDSVKQEVQNLIK-DKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGE
LGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPL
YVTKVMSKSAADLISQARK---KG---NVV---FGEPITASLGIDGTHYWSKNWAKAAAF
VTSPPLS---PDPTTPDYINSLL--ASGDLQLSGSAHCTFSTAQKAIGKDN---FTAIPE
GTNGVEERMSVIWDKAVAT-----------------------------------------
--------GKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIISAKN
HQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKR---
-------I--KARRKMADLHAVPRGMYDGP--------VFD-----LTTT---PKGGTPA
GSAR-GSPTR-PNPP----------VRNLHQSGFSLSGTQVDEGV-RSASKRIVAPPGGR
SNITSLS
>gi|114619339|ref|XP_001161598.	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------MAERKQSGKAAEDEE------
-------------------------------VPAFFKNLGSGSPKPRQKFCGMFCPVEGS
SENKTIDFDSLSVGRGSGQVVAQQRDV---AHLGPDPQPPYSRQGRRAGGEPSV------
-----ESG-------------RKVEIRRASGKEALQNI-------NDQ-----SDRLLIK
GGKIVNDDQSFYADIYMEDGLIKQIGE--NLIVPGG--VKTIEAHSRMVIPGGIDVHTRF
QMP-DQGMTSADD-----------------------------------------------
------------FFQGTKAALAG--GTTMIIDHVVPEP--GTSLLAAFDQWREWADSK-S
CCDYSLHVDISEWHKGIQEEMEALVK-DHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRD
IGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPL
YITKVMSKSSAEVIAQARK---KG---TVV---YGEPITASLGTDGSHYWSKNWAKAAAF
VTSPPLS---PDPTTPDFLNSLL--SCGDLQVTGSAHCTFNTAQKAVGKDN---FTLIPE
GTNGTEERMSVIWDKAVVT-----------------------------------------
--------GKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKT
HNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKR---
-------I--KARSRLAELRGVPRGLYDGP--------VCE-----VSVT---PKTVTPA
SSAK-TSPAKQQAPP----------VRNLHQSGFSLSGAQIGDNIPRRTTQRIVAPPGGR
ANITSLG
