>gi|24585205|ref|NP_523601.2|	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MSSKLISSSFHSSPLSDCFKVGEFERRLDA----------------LL
ADL-QNSVPGQPQQPQP-QYGT-------VQPKHQALQQQQFVDNTP-------------
GYGSLRGKAQPQVYQ------------------EHYSVET--------RSPTAGH-----
-----------------------------------------------------------D
FNGSSTTPGYANQGSLPRQAAGASTGLSELDSLLQDL-----------------------
-------------------QKIDVPVNYSTPVSKYNTMNS---YATVEERPSVDSLLKEL
DNAHIYAVPNGSAHKSPTPGRHVTITVRETKTEKLTGPDGPVGTVEEQIVQQKDSYTPNH
AVPGQQVHQAYT------------------------------SQATKELDDLMASLSDFK
VSNGTNGIGN----------------------------GSHPQQHSSTVQHQTVTDYARP
NKGSQQAHLT------------------------------------------QTIEE---
-------------------------TTIVEDSREDQLDS---------------------
--MLGNLQANMS-RQGVNTVQKGCCNACEKPIVGQVITALGKTWHPE-------------
---------------------------------------------------HFTCNHCSQ
ELGTRNFFERDG-FPYCEPDYHNLFSPRCAYCN-------GAILDKCVTALDKTWHTEHF
FCAQ--CGQQFGEEGFHER-----------------------------------------
-DGKPYCRNDYFEMFAPKCNGCNRAIME--NYISALNSQ-WHPDCFVCRDCRQPFQGGSF
FDHEGLPYCETHYHAKRGSLCAGCSKPITG--RCITAMF-KKFHPEHFVCAFCLKQLNKG
TFKEQKDKPYCHTCFDKIFG--------------------------------------
>gi|115918049|ref|XP_780574.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MEDLDALLADLDNTRIQLKE-NRDRNIQDSPYSYPRGALSPQTPV
SPIYSEIANGFSPSPSPVSSHQNKSSYRIQQVESEPLYQVQDIHLPPSARVYAEPTREPT
RGNSFSQQSPTYNLDYTPRTPTSPPLSDHQEGSVAPPKPARSRSNGRQPPPTLPKPTLPK
PTV------------------------------------------------------FRY
DKAATASYQNSTYQPTPAPPRMAGMPVSELDSLLQELEAAQSQIQNSSNPPPKPPAPAAG
MVKPPRNMNMGGGGGGGGGGGGGVSDLNDMLDDLYTVETTTKTY-TTHSQPPVHSQPPKA
QPAP------------PTHSAPPTHSAPPSQQQHQQPMSRVMTNSTHAPPQASQPQISQP
PLRTA-------------------------------------SSATKELDDLMASLSDFQ
LSPTDTVPPE--------PAYAQPHKVTPPPKPAHPAPNMVNINNTPAQHPAPPAQQYPP
QHPAPPAQHP------------------------------------------APPAQ---
--------------------------QSYAPSQPSQLDS---------------------
--MLGHLNSDVS-RQGVQTMAKGMCAACQKPIAGQIVTALGQTWHSE-------------
---------------------------------------------------HFVCAQCQK
ELGSQTFFERDG-QAFCEEDYHNLFAPKCAYCH-------GPIKDRCVTALDKTWHPEHF
FCAQ--CGKTFGEDGFHEK-----------------------------------------
-NGRAYCKEDYFDMFAPRCGGCNRAIME--NFITALNAQ-WHPECFVCSDCRVPFNEGDF
FDHDGVPYCEIHYHAVRGSLCAGCNKPITG--RCITAMQ-RKFHPEHFVCDYCLKQLNKG
TFKEQNGKAYCHSCFVKLFN--------------------------------------
>gi|114603674|ref|XP_518133.2|	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------MPLPTFIAANTSTLYRFQGHSV
RAAGPSAWAERGAGTLRTPPRRRSPLSPRWSGTRRFRRPSDLQILQSPRVAPTIPTLAAA
LRGETEELGGAFHRRRKSSGRGRDEGVAWCPAPVRALKVEGGCGGGVRTLAADPNEAPWS
PTQSSALAGPAGAGIMDSFKVVLEGPAPWGFRLQG-GKDFNV----------------PL
S-I-SRLTPGGKAAQAGVAVGD-------WVLSIDGENAGSLTHIEAQNKI-------RA
CGERLSLGLSRAQ--------------------PVQSKPQ--------KAPTLPCPPALP
GCV---------------------------------------------------------
---SAQASAPAADPPRYTFAPSVSLN----------------------------------
---------------------KTARPFGAPPPADSAPQQNGQPLRPLVPDASKQWLMENT
EDWR------------PRPGTGQSRSFRILA--HLTGTEFMQDPDEEHLKK---------
------------------------------------------------------------
----------------------------------------------------------SS
QVPGTEAPAS--------------------------------------------STP---
----------------------------QEPWPGPTAPS-----------------PTSR
PPWAVDPAFAERYAPDKTSTVLTRHSQPATPTPLQSRTSIVQAAA---------------
---------------------------------------------------GGVPGGGS-
---------------------NNGKTPVCHQCH-------KVIRGRYLVALGHAYHPEEF
VCSQ--CGKVLEEGGFFEE-----------------------------------------
-KGAIFCPPCYDVRYAPSCAKCKKKITG--EIMHALKMT-WHVHCFTCAACKTPIRNRAF
YMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALG-FSWHDTCFVCAICQINLEGK
TFYSKKDRPLCKSHAFSHV---------------------------------------
>gi|110756925|ref|XP_624308.2|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MDDLDA----------------LL
ADL-QNTVS-SEGNHVGSNATP-------GYGSLNGARTTAYRSYDN-------------
---------------------------------RTSPLPP--------QSPTYQNREAIE
ESI---------------------------------------------------------
-----------AKSGGGGKMPSLNNNLSELDTLLQDLSNAHYNAH---------------
-------------YQERENRISSSGMNGDSSPMLRSPSS------MSASRPTVDSLLEEL
STAV------------PNGDYPSDGRVKVTI--QETSTEIQPVYDGYHSRQ-HGSLNRSE
VQRSYSNGHTA-------------------------------SNATKELDDLMASLSEFK
PVCKLISA---------NRHLSRINSSSHQHQTVTDSPYAKPNKATKSSQSPLPSEGTQT
RIHITETHTT------------------------------------------HHYQQ--Q
HGEPYPPQP-------------------ATQTKQNQLDS---------------------
--MLGNLQADMS-RQGVNTTQKGCCSACEKPIVGQVITALGKTWHPE-------------
---------------------------------------------------HFTCTHCNQ
ELGTRNFFEREG-HPYCEPDYHNLFSPRCAYCN-------GPILDKCVTALEKTWHTEHF
FCAQ--CGKQFGEEGFHER-----------------------------------------
-DGKPYCREDYFDMFAPKCGGCNRAIME--NYISALNSQ-WHPDCFVCRDCRQKFQGGSF
FDHEGLPYCETHYHAKRGSLCAGCHKPITG--RCITAMF-RKFHPEHFVCAFCLKQLNKG
TFKEQNDKPYCHGCFDKLFG--------------------------------------
>gi|149701568|ref|XP_001497365.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSNYSVSLVGPAPWGFRLQG-GKDFNM----------------PL
T-I-SSLKDGGKASQANVRIGD-------VVLSIDGISAQGMTHLEAQNKI-------KG
CTGSLNMTLQRASATSKPELVPVQ---------KGEPKEV--------VKPVPITSPAVS
KVTSTTNMTYNKAPRPFGSVSSPKVTSIPSPSS------------------AFTPAHATT
SSHASPPPVAAVTPPPFAASGLHANANLSADQRPSALSAGKPAVT---------VPRQPT
VTSVCAETAQELAEGQRRGSQGDSKQQNGPPRKHIVERNTEFYHIPTHSDASKKRLIQDT
EDWH------------PRTGTTQSRSFRILA--QITGTEHLKESETDNTKK---------
------------------------------------------------------------
------------------------------------------------------------
-ANNTQEPSQ------------------------------------------QLPVS---
--------------------------VASARSMPERPAS-----------------PASA
RAGVASLTTAAAFKPLGSS---SAVKSPGWQRPHQAAPSTGRISNSATS-----------
---------------------------------------------------SGAGAPASS
AGGQPQPGDQDTLVQRAEHIPAGKRTPMCAHCN-------QVIRGPYLVALGKSWHPEEF
NCAH--CKNTMAYIGFVEE-----------------------------------------
-KGALYCELCYEKFFAPECGRCQRKILG--EVINALKQT-WHVSCFVCVACGKPIRNNVF
HLEDGEPYCETDYYALFGTICRGCEFPIEAGDMFLEALG-STWHDTCFVCSVCCESLEGQ
TFFSKKDKPLCKKHAHSVNF--------------------------------------
>gi|109075015|ref|XP_001103137.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------MSNYSVSLVGPAPWGFRLQG-GKDFNM----------------PL
T-I-SSLKDGGKASQANVRIGD-------VVLSIDGISAQGMTHLEAQNKI-------KG
CTGSLNMTLQRA---------------------SATPKPE--------PVPV--------
------------------------------------------------------------
-----------QKPTVTSVCSETSQELAEGQRR---------------------------
------------GSQGDSKQQNGKIPPKRPPRKHIVERNTEFYHIPTHSDASKKRLIEDT
EDWR------------PRTGTTQSRSFRILA--QITGTEHLKESEADNTKK-AKFDSSLE
DLPKSGPHPPATPQVLTIGSQVAILSKVATTYSSL-------SSSTGNVEDSFEGFRNFS
TFSSPARYSAAVLSSAAATVSAVIAAKTRLYTPERYHSLLDALCISPVSKPLAFSYLQSS
RKSTGSIHVK------------------------------------------KTSNS---
--------------QEPSPQLTSSVA--STRSMPESLDS-----------------PASG
RPGVASLTTAAAFKPVGST---GVIKSPSWQRPNQAVPSTGRISNSATS-----------
---------------------------------------------------SGSVAPASS
ALGQPQPSAQDTLVQRAEHIPAGKRTPMCAQCN-------QVIRGPFLVALGKSWHPEEF
NCAH--CKNTMAYVGFVEE-----------------------------------------
-KGALYCELCYEKFFAPECGRCQRKILG--EVINALKQT-WHVSCFVCVACGKPIRNNVF
HLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALG-YTWHDTCFVCSVCCESLEGQ
TFFSKKDKPLCKKHAHSVNF--------------------------------------
>gi|73953183|ref|XP_865054.1|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MSYSVTLTGPGPWGFRLQG-GKDFNM----------------PL
T-I-SRITPGSKAAQSQLSQGD-------LVVAIDGVNTDTMTHLEAQNKI-------KS
ASYNLSLTLQKS----KRPIPIST---------TAPPVQS--------PLPVIPHQKDPA
GDMS--------------------------------------------------------
---GSPTARSPGPLGPPELGPSSSPSFSQSPPRGGPGTEGAPGPRGQGRPAQYNNPIGLY
SAETLREMAQVYRMSLGGKAWGAGLPGGSLPIKDLAVDSASPVYQAVIKNQNKPE--DEA
DEWA------------RRSSNLQSRSFRILA--QMTGTEYMQDPDEEALRR-SSTPTEHA
PVCTSQAATPLPPASAQPPAAAPRSAASPPPSAAAAC-----AAAATPASSPADSPRPQA
SAYSLAKATS--------PAPASHPYSEASAAPAPKPRVVTTASIRPSVYQPAPAGSKAP
RPGGLTPPTP------------------------------------------HPPTH---
HPPTHSTVPAATYSPSPGPSYSPAPYT-PSPAPGPGYSP-----TPSAAYGGGPVESASR
PPWVADDSFSQKFAPGKSS---SSASRQTLPRGAP-------------------------
---------------------------------------------------TYGPPGPQ-
----VSPLARGI-VQRAERFPASSRTPLCGHCN-------NVIRGPFLVAMGRSWHPEEF
NCAY--CKTSLADVCFVEE-----------------------------------------
-QSNVYCERCYEQFFAPICAKCNTKIMG--EVMHALRQT-WHTTCFVCAACKKPFGNSLF
HMEDGEPYCEKDYVNLFSTKCHGCDFPVEAGDKFIEALG-HTWHDTCFICAVCHVNLEGQ
PFYSKKDKPLCKKHAHAINV--------------------------------------
>gi|125985012|ref|XP_001356270.	Drosophila pseudoobscura
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MPAKLISSSFHSTPLNDCFKVGAFERRLDA----------------LL
ADL-QNSVPGQPQQPQP------------QYGTVQPKQQQQFVDNTP-------------
GYGSLRGKAQPQVYQ------------------EHYSAET--------RSPTVGDFNGSS
SIP--------------------------------------------------------S
NGYPSQGVGSLPRKPAASAVGQNNSGLSELDSLLQDLQNARYNN----------------
------------GGADKGLKEIDVPANYSTPVSKYNTFNS---YATVEERPTMDSLLNEL
DNAH------------IYAVPNGSGHKS-----PTPGRHVTITVRETKTEK-LTGPDGPV
GSLEEQIVQQKDSYTQ--------------------------NSATKELDDLMASLSDFK
VSVNGGSNGT--------------------NGASGHYPNSSQQQHSSTVQHQTVTDYARP
NKGSQQAHLT------------------------------------------QTIEE---
-------------------------TTIVEDSREDQLDS---------------------
--MLGNLQANMS-RQGVNTVQKGCCNACEKPIVGQVITALGKTWHPE-------------
---------------------------------------------------HFTCNHCSQ
ELGTRNFFERDG-FPYCETDYHNLFSPRCAYCN-------GAILDKCVTALDKTWHTEHF
FCAQ--CGQQFGEEGFHER-----------------------------------------
-DGKPYCRNDYFEMFAPKCNGCNRAIME--NYISALNSQ-WHPDCFVCRDCRQPFQGGSF
FDHEGLPYCETHYHAKRGSLCAGCSKPITG--RCITAMF-KKFHPEHFVCAFCLKQLNKG
TFKEQKDKPYCHVCFDKIFG--------------------------------------
>gi|157014748|gb|EAA12524.5|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------MDRTCYGKFDPGARQPYRCTLRDRGIAPGY-A----------------LL
ADL-QNTVPGHNQQQHGGGGAS-------SVPGYGSLNGVRNKQQTSPVPV-------RI
RHLRGCQTYQNT---------------------TAKTVTE--------SRATNGYNGSLP
RS----------------------------------------------------------
---TTPHNSLPRSSTPQKLQTSASGNLSELDSLLQDL-----------------------
---------------------SSARYGNVAEKRKSAPTCA--VRVSRIKRPSVDSLLEEL
SNAH------------SNPIYAVPHGNQNA---NQPGRQVTITVRETTTEKLTGTPSAHH
PVAKLHSLHYMRLQSMQPAHQDTTLAQNESHT----------SSATKELDDLMASLSDFK
VICALNSIGT-------------LQQMKHSFASVNPHSCICTLALCPN----QGTSHYQS
TLTTVSTTEH------------------------------------------LPPAS---
---------------------------------SDQLDS---------------------
--MLGNLTADMS-RQGVNTTQKGCCNACDKPIVGQVITALGKTWHPE-------------
---------------------------------------------------HFTCNHCNQ
ELGTRNFFERDG-NPYCEPDYHNLFSPRCAYCN-------GPILDKCVTALEKTWHTEHF
FCAQ--CGQQFGEDGFHER-----------------------------------------
-DGKPYCRNDYFDMFAPKCNGCNRAIME--NYISALNSQ-WHPDCFVCRDCREPFHGGSF
FDHEGLPYCETHYHAKRGSLCAGCSKPITG--RCITAMF-KKFHPEHFVCAFCLKQLNKG
TFKEQNDKPYCHQCFDKLFG--------------------------------------
>gi|45384484|ref|NP_990315.1|	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MDDLDA----------------LL
ADL-ESTTSHISKRPVFLTEET-------PYSYPTGNHTYQEIAVPPPVPP-------PP
SSEALNGTVIDPLDQWQPSVSRYGHQQPQ----SQSPIYS--------SSAKSSSASVPR
DGLSSPSPRAS----------------------------------------------EEE
HVYSFPNKQKSAEPSPTMTSTSLGSNLSELDRLLLELNAVQHNPPSGFSADEVSRSPSLP
NVT---------GPHYVIPESSSSAGGKAAPPTKEKPKRNG-GRGIEDVRPSVESLLDEL
ESSV------------PSPVPAITVSQG-----EVSSPQRVNASQQQTRIS-A-------
------------------------------------------SSATRELDELMASLSDFK
F-----------------------------------------------------------
-MAQGKAGGS------------------------------------------SSPPS---
----------------------------TTPKPGSQLDT---------------------
--MLGSLQSDLN-KLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPE-------------
---------------------------------------------------HFVCTHCQE
EIGSRNFFERDG-QPYCEKDYHNLFSPRCYYCN-------GPILDKVVTALDRTWHPEHF
FCAQ--CGVFFGPEGFHEK-----------------------------------------
-DGKAYCRKDYFDMFAPKCGGCARAILE--NYISALNTL-WHPECFVCRECFTPFINGSF
FEHDGQPYCEVHYHERRGSLCSGCQKPITG--RCITAMG-KKFHPEHFVCAFCLKQLNKG
TFKEQNDKPYCQNCFLKLFC--------------------------------------
>gi|47214002|emb|CAG01877.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------DA----------------LL
ADL-ESTTSHISKRPLFLSDEA----------------AYSFPSFSPAQK----------
---------------------------------SPWSRES--------SSPSQPVCE---
----------------------------------------------------------ED
HVYSFPNKQKSSDSSAAAMNSALGSNLSELDRLLLELNAVQQSAPAFPTEEEAAPPLPSS
S------------IIHQIHENGVSPAGRTAPATLEKPKRGGAGRVMEDARPSVESLLDEL
ESSV------------PSPIPT-----------PLAAPDEQADAPEETPTQ-QQARMSA-
------------------------------------------SSATRELDELMASLSDFK
VQSNLKSVIRRTKETSHVHPMYREGLSRRKMGPIIVNKSNSQDQLIEELQGKLGIGRTEQ
GTRRKRQPEE------------------------------------------WLTEGVIV
VSNPQRKREEGVRTAVAKIQSQGKVSPTGPPKPSNKLDN---------------------
--MLGSLQSDLN-RLGVQTVAKGVCGACKKPIVGQVVTAMGRTWHPE-------------
---------------------------------------------------HFVCTHCQE
EIGSKNFFERDG-QPYCEKDYHNLFSPRCQYCN-------GPILDKVVTALDKTWHPEHF
FCAQ--CGSFFGAEGFHEK-----------------------------------------
-DGKAYCRKDYFDMFAPKCGGCARAILE--NYISALNSL-WHPECFVCRECFTPFVNGSF
FDHDGQPYCEAHYHERRGSLCSGCQKPITG--RCITAMG-KKFHPEHFVCAFCLKQLNKG
TFKEQNEKPYCQICFIKLF---------------------------------------
>gi|148226543|ref|NP_001081420.	Xenopus laevis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MDDLDA----------------LL
ADL-ESTTSHISKRPVFLAEET-------PYSFPSGCHTYQEITIPA-----------AP
AAKTLNGTLPDSLDSWT----------------NNTPIQQ--------ENPLYCSSGAKD
ISGSPSFG-------------------------------------------------EEE
HVYSFPNKQRSAEPSPTVMSSSFGSNLSELDRLLLELNAVQEAPTSSLSSEMIHSLYPKD
DLIRSMPQPVAPAPLFSALDSSGSACMKNVQPSSEKPNRNG-TQGIEDVRPSVESLLDEL
ENSV------------PPPVASVIMSQG-----DISSPQQDNSSEHQTRIS-A-------
------------------------------------------SSATRELDELMASLSDFK
I-----------------------------------------------------------
-MAKGKSVSN------------------------------------------SPPSN---
-----------------------------TPKPGSQLDN---------------------
--MLGSLQSDLN-KLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPE-------------
---------------------------------------------------HFVCTHCQD
EIGSRNFFERDG-QPYCEKDYHNLFSPRCFYCN-------GPILDRVVTALDRTWHPEHF
FCAQ--CGAFFGPEGFHER-----------------------------------------
-DGKAYCRKDYFDMFAPKCGGCTHAILE--NYISALNTL-WHPECFVCRECFTPFINGSF
FEHDGQPYCEMHYHERRGSLCSGCQKPITG--RCITAMG-KKFHPEHFVCAFCLKQLNKG
TFKEQNDKPYCQNCFVKLFC--------------------------------------
>gi|91083721|ref|XP_967045.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MASLITVRLSKGDSPSLGFRLQG-GKDFGT----------------PL
V-I-QKVNGGSPAERAGLLAGD-------SVIKVNNTDVFNLRHKDAQDVI-------IR
AGPAFELTVQRGGSVWKPSVI------------PTGTIHT--------ASPTSPITKTSL
VANK-----------------------------------------------------KEN
IGSIGTGHNLSAKPFSAQLNGAVNGGPKLVNN-------------------QYNSPLKLY
SEESIAETL----SAQTEVLSTGALGVNFKKNEKNYDASNSAVYRMLQEAEKEPKTPEAV
---S------------PRSDFYATHSHAVGG--RQATSPRSNTPDDHSRLS-SRLGDYPN
TIPNQEGVTKCTECERVI------------------------VGVFVRIKDKNLHVECFK
CSTCGTSLKNVGYYNINNKLYCDVHAKLAARTNPPAPNLV-PITVPPGGKAPASAISTAL
ATHSLPSPSP------------------------------------------LSPKT--N
LAQPFQAGN-------------------YSTAPKPFA-----------------------
--SVSAPTSNQSFNTLPKTAPLSPIASAPAPASYSPVSSTGRLPAKPVGS----------
---------------------------------------------------VFKGSGGGR
QAGAIGVAPKRGRGVLNAAALGGTRIPLCASCH-------SQIRGPFITALGKIWCPEHF
ICATPSCRRPLQDLGFVEE-----------------------------------------
-QGQLYCEYCFEQYLAPPCAKCSSKIKG--DCLKAIGKN-FHPECFNCVYCGKLFGNSPF
FLEDGXXXXXSDWNELFTTKCFACGFPVEAGDRWVEALN-NNYHSQCFNCTMCKKNLEGQ
SFFAKGGRPFCKNHAR------------------------------------------
>gi|119600733|gb|EAW80327.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MSYSVTLTGPGPWGFRLQG-GKDFNM----------------PL
T-I-SRITPGSKAAQSQLSQGD-------LVVAIDGVNTDTMTHLEAQNKI-------KS
ASYNLSLTLQKS----KRPIPIST---------TAPPVQT--------PLPVIPHQKVVV
NSP---------------------------------------------------------
---ANADYQERFNPSALKDSALSTHKPIEVKGLGGKATIIH---------AQYNTPISMY
SQDAIMD------AIAGQAQAQGSDFSGSLPIKDLAVDSASPVYQAVIKSQNKPE--DEA
DEWA------------RRSSNLQSRSFRILA--QMTGTEFMQDPDEEALRR-SSTPIEHA
PVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADSPRPQA
SSYSPAVAAS-------SAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSP
SPGANYSPTP------------------------------------------YTPSP---
-APAYTPP--------------------YTPSPAPNYNP-----APSVAYSGGLAEPASR
PPWVTDDSFSQKFAPGKST---TSISKQTLPRGGP-------------------------
---------------------------------------------------AYTPAGPQ-
----VPPLARGT-VQRAERFPASSRTPLCGHCN-------NVIRGPFLVAMGRSWHPEEF
TCAY--CKTSLADVCFVEE-----------------------------------------
-QNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHALRQT-WHTTCFVCAACKKPFGNSLF
HMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALG-HTWHDTCFICAVCHVNLEGQ
PFYSKKDRPLCKKHAHTTHTHTHTHDH-------------------------------
>gi|126723551|ref|NP_001075517.	Oryctolagus cuniculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MEELDA----------------LL
EEL-E-------------------------------------------------------
-----RSTLQDS---------------------DEYSNSA--------PLPL--------
------------------------------------------------------------
-----------------DQSSRKESNLDETSKML--------------------------
-----------------------------SVQDSTNPFPVQLVYTTNIQDRNVYSEVQE-
----------------PKKSPPPAK-----------------------------------
------------------------------------------TSAAAQLDELMAHLSEMQ
AKVSV-------------------------------------------------------
KADAGKKPVS------------------------------------------ENLDH---
---------------------------------KASLDS---------------------
--MLGGLEQELQ-NLGIPTVPKGHCASCQKPIVGKVIHALGQSWHPE-------------
---------------------------------------------------HFICTHCKE
EIGSSPFFERSG-LAYCPKDYHHLFSPRCAYCA-------APILDKVLTAMNQTWHPEHF
FCSH--CGEVFGTEGFHEK-----------------------------------------
-DKKPYCRKDFLAMFSPKCGGCNRPVLE--NYLSAMNTV-WHPECFVCGDCFSSFSTGSF
FELEGRPFCELHYHQRRGTLCHGCGQPITG--RCISAMG-HKFHPEHFVCAFCLTQLSKG
VFREQNDKTYCQPCFNKLFSL-------------------------------------
>gi|108884446|gb|EAT48671.1|	Aedes aegypti
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MQTYQT----------------SS
KTV-T------------------------ETRSANG------------------------
----YNGSLPR----------------------STTPHQN--------SLP---------
------------------------------------------------------------
-----------RSNTPQRLQTSTSGNLSELDSLLQDL-----------------------
-------------------SSAHTPNNGTTSPSPYAINDT-------IKRPSVDSLLDEL
SAAN------------ANPIYAVPYGNQSPNPQPHPGRQVTITVRETTTEKMTGTPSANY
QNQLYQQQVAQNEQSNYA------------------------SSATKELDDLMASLSDFK
ITSGSHQLQS----------------------------------VTDYAKPNQGTAHYQS
TLTTVTTTEQ------------------------------------------LPPAS---
----------------------------------DQLDS---------------------
--MLGNLQADMS-RQGVNTTQKGCCNACDKPIVGQVITALGKTWHPE-------------
---------------------------------------------------HFTCNHCNQ
ELGTRNFFERDG-NPYCESDYHNLFSPRCAYCN-------GPILDKCVTALEKTWHTEHF
FCAQ--CGQQFGEDGFHER-----------------------------------------
-DGKPYCRNDYFDMFAPKCNGCNRAIME--NYISALNSQ-WHPDCFVCRDCRQPFFGGSF
FDHEGLPYCETHYHAKRGSLCAGCSKPITG--RCITAMF-KKFHPEHFVCAFCLKQLNKG
TFKEQNDKPYCHQCFDKLFG--------------------------------------
>gi|126272208|ref|XP_001363449.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------MAYSVTLTGPGPWGFRLQG-GKDFNM----------------PL
T-I-SRITPGSKAAQSQLTQGD-------LVVAIDGVNTDTMTHLEAQNKI-------KS
ASYNLSLTLQKS----KRPIPIST---------SAPRIES--------PMPVIPHQKDSA
SEMNGNLTALSSIPSPKGEPPTPGMTNGTGVGT------------------LSIQEASQT
FSSSSQATIISSHMVTSEPSPPRGSQGLKANPEATADSLSPKAQVGSGQQRQYNNPIGLY
SAETLREMAEMYQLSQRGKAPGTAPPRGNIPVKDLAVDSASPVYQAVIKNQNKPE--DEV
DEWA------------RRSSNLQSRSFRILA--QMTGTEYMQDPDEEALRR---------
------------------------------------------SRILGSSYSPAASASHAP
TYNEA-------------------------PATAPKPRVVTTASIRPSVYQSVPTSSYSP
APGATYSPAPA-----------------------------------------YTPSP---
-APAYTPSPAPAYTPSPAPAYTPSPAPAYTPSPAPSYNPSPYSPAPSATYSSGPGEPASR
PPWVTDDNFSQKFAPGKTT---TSISKQVLPRGAPGPSP---------------------
---------------------------------------------------GYTPAGTQ-
----VPTLARGT-IQRAERFPASNRTPHCGHCN-------SIIRGPFLVAMGRSWHPEEF
NCAY--CKTSLADVCFVEE-----------------------------------------
-QNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHALRQT-WHTTCFVCAACRKPFGNSLF
HMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALG-HTWHDTCFICAVCHVNLEGQ
PFYSKKDKPLCKKHAHAINV--------------------------------------
>gi|63030039|gb|AAY27883.1|	Danio rerio
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---------------MTSYNVSLSGPPPWGFRLQG-GKDFNM----------------PL
T-V-SRITPGSKAASSNLIQGD-------IIVAIDGVSTDGMTHLEAQNKI-------KS
ANFNLALTMQRS----KRPTPVPI---------ATPRIES--------PMPVIPHQKDHP
VQINGAL-----------------------------------------------------
---SSSAETNSCKNTSPSYSSVLSSSGETSVPAQGHLAAPRDKSSSRQKSQQYNSPIGLY
SAETLREMAM---LQERAKGSGSGMTSGSAAEHAPVSTSIAPVCPPTIAALPNQLLSE--
----------------PLIANQAPEPEVELIPEQTTVPSYSLQTSMGYTSQYKTSISSSY
SQPPPMQQPPLMQ-----------------------------QPPLMQQPPLMQQPPPMH
QHPPMHQPPPMQQPPLMQQPPPMQHSSIQIPVGPPPPKVVSTATIMPASYPAGPA----P
APPMVHKPAP------------------------------------------PPPAP---
---------------------------PAAPASSSNRPP---------------------
--WVTDDNFAQKFDPSKPT-PNTNIKVQPLPQAAPPPPSIISNPVPAAPSP---------
---------------------------------------------------AFNPAPPPF
NPAPFPPVARGV-AQRAERFAASNRTPLCATCN-------NIIRGPFLVALGRSWHPEEF
NCHY--CHTSLADVSFVEE-----------------------------------------
-QNNVYCENCYEEFFAPTCARCSTKIMG--EVMHALRQT-WHTTCFVCAACGKPFGNSLF
HMEDGEPYCEKDYIALFSTKCHGCDFPVEAGDKFIEALG-HTWHDTCFVCAVCHVNLEGQ
PFYSKKDKPLCKKHAHAINV--------------------------------------
>gi|109503089|ref|XP_573863.2|	Rattus norvegicus
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----------------MSYSVTLTGPGPWGFRLQG-GKDFNM----------------PL
T-I-SRITPGSKAAQSQLSQGD-------LVVAIDGVNTDTMTHLEAQNKI-------KS
ASYNLSLTLQKS----KRPIPIST---------TAPPIQS--------PLPVIPHQKVVA
NSP---------------------------------------------------------
---ANADYQERFNPSVLKDSALSTHKPIEVKGLGGKATIIH---------AQYNTPISMY
SQDAIMDAIAG-QAQAQGSDFSGASPLASLPVKDLAVDSASPVYQAVIKTQSKPE--DEA
DEWA------------RRSSNLQSRSFRILA--QMTGTEYMQDPDEEALRR-SSTPIEHA
PVCTSQATSPLLPASAPSPAAASPIAASPTLATAAAAHAVA-ASAAGPASSPVENPRPQA
SAYSPAAATS-------PAPAAHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASPYSP
SPGANYSPTP------------------------------------------YTPSP---
-APAYTPSPAPTYTPSPAPTYSPSPAPAYTPSPAPNYNP---TP--SAAYSGGPSESASR
PPWVTDDSFSQKFAPGKST---TSVSKQTLPRGAP-------------------------
---------------------------------------------------AYNPTGPQ-
----VTPLARGT-FQRAERFPASSRTPLCGHCN-------NVIRGPFLVAMGRSWHPEEF
NCAY--CKTSLADVCFVEE-----------------------------------------
-QNNVYCERCYEQFFAPICAKCNTKIMG--EVMHALRQT-WHTTCFICAACKKPFGNSLF
HMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALG-HTWHDTCFICAVCHVNLEGQ
PFYSKKDKPLCKKHAHAINV--------------------------------------
>gi|84872215|ref|NP_001034163.1	Mus musculus
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----------------MSYSVTLTGPGPWGFRLQG-GKDFNM----------------PL
T-I-SRITPGSKAAQSQLSQGD-------LVVAIDGVNTDTMTHLEAQNKI-------KS
ASYNLSLTLQKS----KRPIPIST---------TAPPIQS--------PLPVIPHQKVVA
NSP---------------------------------------------------------
---ANADYQERFNPSVLKDSALSTHKPIEVKGLGGKATIIH---------AQYNTPISMY
SQDAIMDAIAG-QAQAQGSDFSGASPLASLPVKDLAVDSASPVYQAVIKTQSKPE--DEA
DEWA------------RRSSNLQSRSFRILA--QMTGTEYMQDPDEEALRR-SSTPIEHA
PVCTSQATSPLLPASAQSPAAASPIAASPTLATAAATHAAA-ASAAGPAASPVENPRPQA
SAYSPAAAAS-------PAPSAHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASSYSP
SPGANYSPTP------------------------------------------YTPSP---
-APAYTPSPAPTYTPSPAPTYSPSPAPAYTPSPAPNYTP-----TPSAAYSGGPSESASR
PPWVTDDSFSQKFAPGKST---TTVSKQTLPRGAP-------------------------
---------------------------------------------------AYNPTGPQ-
----VTPLARGT-FQRAERFPASSRTPLCGHCN-------NVIRGPFLVAMGRSWHPEEF
NCAY--CKTSLADVCFVEE-----------------------------------------
-QNNVYCERCYEQFFAPICAKCNTKIMG--EVMHALRQT-WHTTCFVCAACKKPFGNSLF
HMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALG-HTWHDTCFICAVCHVNLEGQ
PFYSKKDKPLCKKHAHAINV--------------------------------------
>gi|149635448|ref|XP_001512180.	Ornithorhynchus anatinus
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-----------------------TSPNP------------------------------VL
S-L-LQLKDGGKASQANVRIGD-------VVVSVDGINADGMTHLEAQNKI-------KS
CTGSLNLTLQRA-PTAPKPDPV--PIQKGEPKEIVKPVPI--------TSPALSKPTANV
AYNKVPRPFGAVVAPKVTSIPSP----------------------------------SSA
FTPAPATVSSHTSPPPFAAPGLHATPRPGADPRPPASAVASNTAVPVPRQPTTYGATTGM
PSDAGPEGAE---GQGRGTQWAAKQQNG-PPRKHIVERYTEFHHTPTPSDASKKRLIEDT
EDWH------------PRTGTTQSRSFRILA--QITGTEHLKESEADNTKK-T-------
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NDSSDVINTP------------------------------------------AYPVS---
--------------S--------------ARSPAEGTEP-----------------PATG
RPGVASFSTPAAFRPPGAA---NLAKTPSWQRPNKPAPLTGRISNSGSQ-----------
---------------------------------------------------AGASALSSS
SAAQPPLNEQDTLVQRAEHIPAGKRTPMCAHCN-------QVIRGPFLVALGKSWHPEEF
NCAH--CKNTMAYIGFVEE-----------------------------------------
-KGALYCELCYEKFFAPDCARCQRKILG--EVINALKQT-WHVSCFVCVACGKPIRNNIF
HLEDGDPYCETDYYAMFGTICRGCEFPIEAGDMFLEALG-HTWHDTCFVCSVCCDSLEGQ
TFFSKKDKPLCKKHAHSINI--------------------------------------
>gi|120419518|gb|ABM21560.1|	Bos taurus
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---------------MDSFKVVLEGPAPWGFRLQG-GKDFNV----------------PL
S-I-SRLTPGGKAAQAGVAVGD-------WVLSIDGENAGGLTHIEAQNKI-------RA
CGERLSLSLSRAQPA------------------QSKPQKA--------LAPA--------
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-----------ADPPRYTFAPSASLN----------------------------------
---------------------KTARPFGANPPADSAPQQNGQPLRPLVPDASKQRLMEDT
EDWR------------PRPGTGQSRSFRILA--HLTGTEFMQDPDEEHLKK---------
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----------------------------------------------------------SS
QVPRTEAPTP------------------------------------------ASATP---
----------------------------QEPWPGPTTPS-----------------PTSR
PPWAVDPAFAERYAPDKTSTVLTRHTQPATPTPMQNRTSIVQAAAGG-------------
---------------------------------------------------GHGGGGGS-
----------------------NGKTPVCHQCH-------KVIRGRYLVALGRAYHPEEF
VCSQ--CGKVLEEGGFFEE-----------------------------------------
-KGAIFCPPCYDVRYAPSCAKCKKKITG--EVMHALKTT-WHVHCFTCAACKAPIRNRAF
YMEEGAPYCEPDYEKMFGTKCRGCDFKIDAGDRFLEALG-FSWHDTCFVCAICQINLEGK
TFYSKKDKPLCKSHAFSHV---------------------------------------
>gi|27465579|ref|NP_775148.1|	Rattus norvegicus
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---------------MDSFKVVLEGPAPWGFRLQG-GKDFNV----------------PL
S-I-SRLTPGGKAAQAGVAVGD-------WVLSIDGENAGSLTHIEAQNKI-------RA
CGERLSLGLSRAQPA------------------QSKPQKA--------LTP---------
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----------PADPPRYTFAPSASLN----------------------------------
---------------------KTARPFGAPPPTDSALSQNGQLLRQLVPDASKQRLMENT
EDWR------------PRPGTGQSRSFRILA--HLTGTEFMQDPDEEFMKK---------
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----------------------------------------------------------SS
QVPRTEAPAP------------------------------------------ASTIP---
----------------------------QESWPGPTTPS-----------------PTSR
PPWAVDPAFAERYAPDKTSTVLTRHSQPATPTPLQNRTSIVQAAAG--------------
---------------------------------------------------GGTGGGSN-
----------------------NGKTPVCHQCH-------KIIRGRYLVALGHAYHPEEF
VCSQ--CGKVLEEGGFFEE-----------------------------------------
-KGAIFCPSCYDVRYAPSCAKCKKKITG--EIMHALKMT-WHVPCFTCAACKTPIRNRAF
YMEEGAPYCERDYEKMFGTKCRGCDFKIDAGDRFLEALG-FSWHDTCFVCAICQINLEGK
TFYSKKDKPLCKSHAFSHV---------------------------------------
