>gi|90083461|dbj|BAE90813.1|	Macaca fascicularis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVSFGDLLA
ARCVFTGEGRTEATH--IGGTSSDEMCNLYIMYYMEAKHA-VSFMTCTQNVAPDTF-RTI
PPEANIPIPVKSDMVMM--HEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLG
EREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDAREGAEHER-GNAILVRDRI
HKFHRLVSTLRPPE-SRVSSLQQPLPGEGTWEP---EHTGDFHMEEALDWP--GVYLLPG
--QVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAV-
-LQSSGKNLFYLPHGLSIDKDGNY-------------------WVTDVALHQ---VFKLD
PNNKEG-PI-----LILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQ-F
SPSGEFITQWGEES---SGS------SPLP-GQ---FTVPHSLALVSHLGQLCVADRENA
RIQCFKTDTKEFVREIK-----HSSF--GRNVFAISYIP---GLLFAVNGKPHFGDQ-EP
-----VQGFVMNFSSGEIIDIFK---PVRKH-----FDMPHDIVASED--GT-VYIGDAH
TNTVWKFTLTE---KVEHRSVK--------------------------------------
--------------------------------------------KAGIEVQEIK------
------------------------------------------------------------
------------------------------------------------------------
----------ADSEHK-LETS--SGRVLGRFRGKGSGGLNLG---NFFASRKGYSRK--G
FDRLSTEGSDQEKEEDDGSESE-EEYSAPLPAPAPSSS--
>gi|21070984|ref|NP_000910.2|	Homo sapiens
MAGRVPS-----LLVLLVFPSSCLA---FRSPLSVFK-----------------------
------RFKETTRPFSNECLGTTRPVVPIDSSDFALDIRM-------PGVTPKQSDTYFC
MSMRIPVDEEAFVIDFKPRASMDTVHHMLLFGC-NM---------P-SSTGSYWFCDE--
GTCTDKANILYAWARNAPPTRL----------PKGVGFRVGGETGSKYFVLQVHYGD--I
SAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVV-----NSDISCHY-K
NYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLA
ARCVFTGEGRTEATH--IGGTSSDEMCNLYIMYYMEAKHA-VSFMTCTQNVAPDMF-RTI
PPEANIPIPVKSDMVMM--HEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLG
EREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDAREGAEHER-GNAILVRDRI
HKFHRLVSTLRPPE-SRVFSLQQPPPGEGTWEP---EHTGDFHMEEALDWP--GVYLLPG
--QVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAV-
-LQSSGKNLFYLPHGLSIDKDGNY-------------------WVTDVALHQ---VFKLD
PNNKEG-PV-----LILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQ-F
SPSGKFITQWGEES---SGS------SPLP-GQ---FTVPHSLALVPLLGQLCVADRENG
RIQCFKTDTKEFVREIK-----HSSF--GRNVFAISYIP---GLLFAVNGKPHFGDQ-EP
-----VQGFVMNFSNGEIIDIFK---PVRKH-----FDMPHDIVASED--GT-VYIGDAH
TNTVWKFTLTE---KLEHRSVK--------------------------------------
--------------------------------------------KAGIEVQEIKEAEAVV
ETKMENKPTSSELQK---------------------------------------------
--------------------MQEKQKLIKEPGSGVPVVLITTLLVIPVVVLLAIAIFIRW
KKSR---AFGADSEHK-LETS--SGRVLGRFRGKGSGGLNLG---NFFASRKGYSRK--G
FDRLSTEGSDQEKE-DDGSESE-EEYSAPLPALAPSSS--
>gi|114152772|sp|P08478|AMD1_XE	Xenopus laevis
MASLSSS----FLVLFLLFQNSCYC---FRSPLSVFK-----------------------
------RYEESTRSLSNDCLGTTRPVMSPGSSDYTLDIRM-------PGVTPTESDTYLC
KSYRLPVDDEAYVVDFRPHANMDTAHHMLLFGC-NI---------P-SSTDDYWDCSA--
GTCMDKSSIMYAWAKNAPPTKL----------PEGVGFRVGGKSGSRYFVLQVHYGN--V
KAFQDKHKDCTGVTVRVTPEKQPQIAGIYLSMSVDTVIPPGEEAV-----NSDIACLY-N
RPTIHPFAYRVHTHQLGQVVSGFRVRHGKWSLIGRQSPQLPQAFYPVEHPVEISPGDIIA
TRCLFTGKGRTSATY--IGGTSNDEMCNLYIMYYMDAAHA-TSYMTCVQTGEPKLF-QNI
PEIANVPIPVSPDMMMMMGHGHHHTEAEPEKNTGLQQPKREEEEVLDQ------------
------------------------------------------------------------
----------------------------------------DVHLEEDTDWP--GVNLKVG
--QVSGLALDPKNNLAIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPSSSKV-
-LKSTGKNLFFLPHGLTIDRDGNY-------------------WVTDVALHQ---VFKL-
GAGKET-PL-----LVLGRAFQPGSDRKHFCQPTDVAVDPITGNFFVADGYCNSRIMQ-F
SPNGMFIMQWGEET---SSN------VPRP-GQ---FRIPHSLTMVPDQGQLCVADRENG
RIQCFHAETGNFVKQIK-----HQEF--GREVFAVSYAP--GGVLYAVNGKPYYGYS-AP
-----VQGFMLNFSNGDILDTFI---PARKN-----FDMPHDIAAADD--GT-VYVGDAH
ANAVWKFSPS----KAEHRSVK--------------------------------------
--------------------------------------------KAGIEVEEITETEIF-
ETHIRSRPKTNESVEKQTQEKQQKQKNSAGVSTQEKQNVVQEINAGVPTQEKQNVVQESS
AGVSTQEKQSVVQESSAGVSTQEKQSVVQESSAGVSFVLIITLLIIPIAVLIAIAIFIRW
RKVR---MYGGDIDHK-SESS--SVGILGKLRGKGSGGLNLG---TFFATHKGYSRK--G
FDRLSTEGSDQEKDDDDGSDSE-EEYSAPPIPPAPVSSS-
>gi|2493899|sp|P97467|AMD_MOUSE	Mus musculus
MAGRARSR-LLLLLGLLALQSSCLA---FRSPLSVFK-----------------------
------RFKETTRSFSNECLGTTRPITPIDSSDFTLDIRM-------PGVTPKESDTYFC
MSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGC-NM---------P-SSTGSYWFCDE--
GTCTDKANILYAWARNAPPTRL----------PKGVGFRVGGETGSKYFVLQVHYGD--I
SAFRDNHKDCSGVSLHLTRVPQPLIAGMYLMMSVNTVIPPGEKVV-----NSDISCHY-K
MYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVAFGDILA
ARCVFTGEGRTEATH--IGGTSSDEMCNLYIMYYMEAKHA-VSFMTCTQNVAPDMF-RTI
PEEANIPIPVKSDMVMI--HGHHKETENKEKSALIQQPKQGEEEAFEQGDFYSLLSKLLG
EREDVVHVHKYNPTEKTESGSDLVAEIANVVQKKDLGRSDAREGAEHEEGGNAILVRDRI
HKFHRLESTLRPAE-SRALSFQQP--GEGPWEP---ELAGDFHVEEALEWP--GVYLLPG
--QVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNKAEI-
-LQSSGKNLFYLPHGLSIDTDGNY-------------------WVTDVALHQ---VFKLE
PRSKEG-PL-----LVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQ-F
SPSGKFITQWGEES---SGS------SPKP-GQ---FSVPHSLALVPHLNQLCVADRENG
RIQCFKTDTKEFVREIK-----HASF--GRNVFAISYIP---GFLFAVNGKPYFGDQ-EP
-----VQGFVMNFSSGEIIDVFK---PVRKH-----FDMPHDIVASED--GT-VYIGDAH
TNTVWKFTLTESRLEVEHRSVK--------------------------------------
--------------------------------------------KAGIEVPEIKEAEAVV
EPKVKNKPTSSELQK---------------------------------------------
--------------------MQEKKKLIKDPGSGVPVVLITTLLVIPVVVLLAIAMFIRW
KKSR---AFG-DHDRK-LESS--SGRVLGRLRGKGSSGLNLG---NFFASRKGYSRK--G
FDRVSTEGSDQEKDEDDGSESE-EEYSRPLPTPAPSS---
>gi|7682317|gb|AAF67216.1|	Aplysia californica
MCVRAP------MTRLGVLAVCCVV-----------------------------------
------SLVMSPTLSADPTTRVMDEVIEADPTTHSMSLLM-------RGAKPSQPDAYLC
TAYPV-TDLETYIYKFQAQANASTAHHMLLYGC-DG---------PAYSTADIWHCP---
SVCRGQQTILFAWAKNAPPTEL----------PRDVGHRVGQRSNVKTLVLQVHYAK---
GFVRNESPDHSGIIVHMTDRRPKFVAGIFLMMSTWFQVPPHRESY-----PVDMSCVYLE
QKPMYPFAFRTHAHGLGKVITGY-LYNGTYQLIGKGNPQWPQAFYPVEDVIEVKPGDSLA
ARCTYDSTHMDQRVG--VGATGSDEMCNFYIMYYTDSSVQ-RPGAECMNDQLPELTGAHF
PSSVSQPLPPNPQLEEV-ASGHHHAHHQHG---------------------------MSG
GQGGVAQVHTTQ------------------------------------------------
------VHTTQTPT-TQTPTTQTPTMQEIHF---------DHPLQLNTSWP--GVELTVG
--QVGGVSVDQRGNLYVFHRGSRVWNAASFDIDNNFQFQD-SPITEDVVLVTDS-TGHK-
-IRSFGAGRYFLPHGIQVDHKDNI-------------------WLTDVALHQ---VFKI-
PAGSDT-PT-----LTIGHRFQHGEELTFFCKPTDVAV-LSSGEFFVSDGYCNSRVVK-F
SADGKVIKAWGEKNLE-FGV------SPPP-GT---FDVPHSVTVSEGTGQLCVADRENG
RVQCFDLE-GNFDHLIR-----HKEF--GPRLFAVEVCPLQ-GVLYAVNGPAYDGPSDLT
-----VQGFTVDMSSGQLLESWN----IPQG-----LRNPHDLAVDPTTCGS-VYVGELN
PRVVWKLT------RADRSTTP--------------------------------------
--------------------------------------------TPHLH-----------
------------------------------------------------------------
------------------------------------------------------------
-----------------MDTQ---------------------------------------
---IVNNNKKNQIGQAGPSDTQ------------------
>gi|149719405|ref|XP_001504641.	Equus caballus
MAKREDSPGPEVQPMDKQFLVCSICLDRYRCP----------------------------
------KVLPCLHTFCERCL---QNYIPAQSLTLSCPVCRQTSILPEQGVSALQNNFFIS
SLME----------------AMQ-----------QA---------P--------------
DGARD---------------------------PED-------------------------
--------------------PHPLSAVA----------------------GRPLSCPNHE
GKTMEFYCEACETAMCGECRAGEHREHGT-VLLRDVVEQHKAALQRQLEAVRGRLPQLSA
AIAL-------------VGGIS-QQLQERKAEALAQISAAFEDLEQALQQRKQALV-SDL
EAICGAKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVR--------KHMR
ERLAALAAQAFPERPHENAQLELVLEVDGL------------------------------
---RRSVLNLGALLTTSATAHETVATGEGLRQALVGQQASLTVTTKDKD----GRLVRTG
SAELRAEITGPDGTRLPVPVVDH----KNGTYELVYTARTEGELLLSVLLYGQPVRGS--
------------PFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTG
GKRKDN-PIEDELVFRVGSR---GREKGEFTNLQGVSA-ASSGRIVVAD--SNNQCIQVF
SNEGQFKFRFGV-----RGR------SP---GQ---LQRPTGVA-VDTNGDIIVADYDNR
WVSIFSPE-GKFKTKIG-----AGRL-MGPKGVAVDRN----GHIIVVDNKSCCVFTFQP
--------------NGKLVGRFGGRGATDRH-----FAGPHFVAVNNK--NE-IVVTDFH
NHSVKVY-------SADGEFLF--------------------------------------
--------------------------------------------KFGSHGEGNGQFNAPT
GVAVDSNGNI--------------------------------------------------
-------------------------------------------------------IVADW
GNSR------IQV----FDSS--------------------G---SFLSYINTSAEPLYG
PQGLALTSDGHVVVADAGNHCF-KAYRYLQ----------
>gi|157019953|gb|EAA04373.4|	Anopheles gambiae
------------------------------------------------------------
------MYTKQEKIFS--------------------------------------------
----------------------------------HL------------------------
------------------------------------------------------------
------------------RQMVPFLAGLLIF-------------------SVHFTCTV-E
ARPQTVSS------------NGNNASNAR-------------------------------
-----------------FGAHE----------YAYVSS----------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------WP--IVDRKLG
--SVSAVALDGDGNVVIFHRGSHVWQLSSFDTENRYQEATGGPIAQPTVLKFNRNTGEL-
-LQQWGENLFYMPHGLTVDHEQNY-------------------WLTDVALHQ---VFKFD
LNHSTTEPV-----LTLGTRFEPGNDAYHYCKPTAVAV-LKSGEFFVADGYCNGRIVK-Y
SAEGIPLLSWGRNSFVLTRSFTLPSGQPVPASF---FAIPHALALVPDRDLLCVADREQG
RVQCFHTRNGTFHSQYS-----SPEI--GSRLFSVKYISSDGGLLYTING-PQFVLNPVP
-----VAGHIIELASGNVIGRFQ---PNNPKHA---FSNPHELAVTDD--GSEVYVAELN
PQMVHKF-----------RRIS--------------------------------------
--------------------------------------------PARLTGSTTTTRESAK
EDAAKNSPAKQAKPQ---------------------------------------------
-------------------QQHHPQGNTSKTSVTRSWLLHIAVAAAVRICVLISKRLIRW
VVCR----RPPQAEKGRAKDPCVSATVLSKVSPSVVGRKSSE---CRLLVHCGLSLRLRG
VIVVLFGCLAAVI----GTLREWKKSNFSR----------
>gi|73988285|ref|XP_534038.2|	Canis familiaris
MAKREDSPGPEVQPMDKQFLVCSICLDRYRCP----------------------------
------KVLPCLHTFCERCL---QNYIPAQSLTLSCPVCRQTSILPEQGVSALQNNFFIS
SLME----------------AMQ-----------QA---------P--------------
DGAHD---------------------------PED-------------------------
--------------------PHPLSAVA----------------------GRPLSCPNHE
GKTMEFYCEACETAMCGECRAGEHREHGT-VLLRDVVEQHKAALQRQLEAVRGRLPQLSA
AIAL-------------VGGIS-QQLQERKAEALAQISAVFEDLEQALQQRKQALV-SDL
EAICGAKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVR--------KHMR
ERLAALAAQAFPERPHENAQLELVLEVDGL------------------------------
---RRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKD----GRLVRTG
SAELRAEITGPDGARLPVPVVDH----KNGTYELVYTARAEGELLLSVLLYGQPVRGS--
------------PFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTG
GKRKDN-PIEDELVFRVGSR---GREKGEFTNLQGVSA-ASSGRIVVAD--SNNQCIQVF
SNEGQFKFRFGV-----RGR------SP---GQ---LQRPTGVA-VDTNGDIIVADYDNR
WVSIFSPE-GKFKTKIG-----AGRL-MGPKGVAVDRN----GHIIVVDNKSCCVFTFQP
--------------NGKLVGRFGGRGATDRH-----FAGPHFVAVNNK--NE-IVVTDFH
NHSVKVY-------SADGEFLF--------------------------------------
--------------------------------------------KFGSHGEGNGQFNAPT
GVAVDSNGNI--------------------------------------------------
-------------------------------------------------------IVADW
GNSR------IQV----FDSS--------------------G---SFLSYINTSAEPLYG
PQGLALTSDGHVVVADAGNHCF-KAYRYLQ----------
>gi|126316178|ref|XP_001380068.	Monodelphis domestica
MAGLVNN----LLILFLGLQSSCLA---FRSPLSVFK-----------------------
------RYKESTRSFSNECLGTSRPIIPIDSSDFALDIRM-------PGVTPKQSDTYLC
MSLRLPMDEEAFVIDFKPRASMDTVHHMLLFGC-NM---------P-SSTESYWDCDE--
GTCSDKVNILYAWARNAPPTRL----------PKGVGFRVGGAMGSKYFVLQVHYGD--I
SAFRDNHKDCSGVTLHLTRLQQPLIAGMYLMMSVDTVIPPGEKVV-----NADISCHY-K
KYPMHLFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVSFGDILA
ARCVFSGEGRTEETH--IGGTSSDEMCNLYIMYYMEAKHA-VSFMTCTQNVDPAMF-ATI
PAEANIPIPVKSDLVMM--HGHHKETENKDHLPLLQQPKREEEEVLDQGDFYSLISKLLG
EREDVVHVHKYNPTEKAES--DLVAEIANVVQKKDLDWSGTREGADHNVRGNAILVRDRI
HKFHRLESTLKPPD-NKHFSLQQPPQDEGTQET---EHTGDFHVEEALDWP--GVYLLPG
--QVSGVALDSDGNLVIFHRGDHIWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNNAAV-
-LQSTGKNLFYLPHGLSIDTDGNY-------------------WVTDVALHQ---VFKLD
PRNKGS-PL-----LILGRSMQPGSDKSHFCQPTDVAVDPVTGTIYVSDGYCNSRIVQ-F
SKDGVFMSQWGEES---SGD------NPKP-GQ---FQVPHSLTLVPHFGQLCVADRENG
RIQCFKTETKEFVREIK-----HTAF--GRNVFAISYTP---GLLFAVNGKPQLGDK-QP
-----LQGFVMNFTSGEILDTFT---PVRKR-----FDMPHDLVASED--GT-VYVGDAH
ADTVWKFTTAE---KMEHRSVK--------------------------------------
--------------------------------------------KAGIEVHEVKETETVV
ETKVESKPPSPELLK---------------------------------------------
--------------------MQEKQKLVKETGSGVSFVLITTLLVIPIVVLLAIAVFIWW
KKTR---AYGADSEHK-LETS--SGRILGRLRGKGSGGLNLG---NFFANRKGYSRK--G
FDRLSTEGSDQEKD-DEGSDSE-EEYSAPPPRPASVSSLN
>gi|109078180|ref|XP_001096156.	Macaca mulatta
MAGRVPS----LLVLLLVFPSSCLA---FRSPLSVFK-----------------------
------RFKETTRPFSNECLGTTRPVIPIDSTDFALDIRM-------PGVIPKQSDTYFC
MSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGC-NM---------P-SSTGSYWFCDE--
GTCTDKANILYAWARNAPPTRL----------PKGVGFRVGGETGSKYFVLQVHYGD--I
SAFRDNHKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVV-----NSDISCHY-K
NYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVSFGDLLA
ARCVFTGEGRTEATH--IGGTSSDEMCNLYIMYYMEAKHA-VSFMTCTQNVAPDTF-RTI
PPEANIPIPVKSDMVMM--HEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLG
EREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDAREGAEHER-GNAILVRDRI
HKFHRLVSTLRPPE-SRVSSLQQPLPGEGTWEP---EHTGDFHMEEALDWP--GVYLLPG
--QVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAV-
-LQSSGKNLFYLPHGLSIDKDGNY-------------------WVTDVALHQ---VFKLD
PNNKEG-PI-----LILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQ-F
SPSGEFITQWGEES---SGS------SPLP-GQ---FTVPHSLALVSHLGQLCVADRENA
RIQCFKTDTKEFVREIK-----HSSF--GRNVFAISYIP---GLLFAVNGKPHFGDQ-EP
-----VQGFVMNFSSGEIIDIFK---PVRKH-----FDMPHDIVASED--GT-VYIGDAH
TNTVWKFTLTE---KVEHRSVK--------------------------------------
--------------------------------------------KAGIEVQEIK------
------------------------------------------------------------
------------------------------------------------------------
-----------DSEHK-LETS--SGRVLGRFRGKGSGGLNLG---NFFASRKGYSRK--G
FDRLSTEGSDQEKEEDDGSESE-EEYSAPLPAPAPSSS--
>gi|19923674|ref|NP_037132.2|	Rattus norvegicus
MAGRARSGLLLLLLGLLALQSSCLA---FRSPLSVFK-----------------------
------RFKETTRSFSNECLGTIGPVTPLDASDFALDIRM-------PGVTPKESDTYFC
MSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGC-NM---------P-SSTGSYWFCDE--
GTCTDKANILYAWARNAPPTRL----------PKGVGFRVGGETGSKYFVLQVHYGD--I
SAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGEKVV-----NADISCQY-K
MYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILA
ARCVFTGEGRTEATH--IGGTSSDEMCNLYIMYYMEAKYA-LSFMTCTKNVAPDMF-RTI
PAEANIPIPVKPDMVMM--HGHHKEAENKEKSALMQQPKQGEEEVLEQGDFYSLLSKLLG
ERED-VHVHKYNPTEKTESGSDLVAEIANVVQKKDLGRSDAREGAEHEEWGNAILVRDRI
HRFHQLESTLRPAE-SRAFSFQQP--GEGPWEP---EPSGDFHVEEELDWP--GVYLLPG
--QVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNNAEI-
-LQSSGKNLFYLPHGLSIDTDGNY-------------------WVTDVALHQ---VFKLD
PHSKEG-PL-----LILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQ-F
SPSGKFVTQWGEES---SGS------SPRP-GQ---FSVPHSLALVPHLDQLCVADRENG
RIQCFKTDTKEFVREIK-----HASF--GRNVFAISYIP---GFLFAVNGKPYFGDQ-EP
-----VQGFVMNFSSGEIIDVFK---PVRKH-----FDMPHDIVASED--GT-VYIGDAH
TNTVWKFTLTE---KMEHRSVK--------------------------------------
--------------------------------------------KAGIEVQEIKEAEAVV
EPKVENKPTSSELQK---------------------------------------------
--------------------MQEKQKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRW
KKSR---AFG-DHDRK-LESS--SGRVLGRFRGKGSGGLNLG---NFFASRKGYSRK--G
FDRVSTEGSDQEKDEDDGTESE-EEYSAPLPKPAPSS---
>gi|24652264|ref|NP_610537.2|	Drosophila melanogaster
------------------------------------------------------------
----------MKSTDSAKCLGSKSLAICCLLLHLLLCIR--------PAVSQTQS-----
---------------------------------------------P--------------
------------------------------------------------------------
-----------------------------------------------------------Q
RYLHNVDSNSNNNERLHQILKGSGAGSGATQL------NWPQPPKQTVPNVKTELAKLNN
T-------------------------------YVYQNA----------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------WP--ANNVKLG
--AVTAVSFDKAGNVVIFHRVNRVWGQTTFDNRNQYQEKYRGPIRESTILALEPATGKV-
-QYDWGKNFFYMPHGLTVDPEDNV-------------------WLTDVAMHQ---VFKFP
PRGGDGKPA-----LTLGDAFQPGSGRK-FCKPTSVAV-LDNGDFFVADGYCNARILK-Y
SRKGELILFWGQNTFSGISY------DVAPQNF---FAIPHALTLVPELQLLCAADRENG
RVQCFLSSNGTFHSQYH-----NQLI--GDRLFSMAYTPAAGGQLVIVNG-PTAELGIHP
EHYNEVHGFVLSMRSKQLVSKFG---PNNLQ-----FQNPHDVAVTAD--GNEIYVAELN
PMRIHKFV---------HRSLA--------------------------------------
--------------------------------------------KPMSLSASKDSRDSAI
SQAVGGDQVPAVAVH---------------------------------------------
-------------------------------HPSGKAILVASLMLLFAGSTFALALIFAR
RRKRGCLPFGARGRRHAWEKS---------------DGFKLG---GLLDRDRN------G
FEKLDQQASDEEQETKTLASAQ---YA-------------
>gi|12004980|gb|AAG44250.1|	Calliactis parasitica
MSGLFRY-----------------------------------------------------
------KFFSLVSLLSLAIYSNGASFT-------TLPIRM-------PGAKPLKNDAYLC
TAVKLP-SRSQYIVRFEPKSDPKIAHHMLLFGC-NQ---------P-GSKESIWDCGSS-
SECNGDNNILFAWANGATAKNL----------PKGVGFKVGKTAKINYIVLQVHYKH---
KLRKDAKSDNSGFVLHSTPQRQPYLAGIFLLWSGDVDIPPEKTGV-----HSDIVCQYNQ
QTTMYAFAYRTHAHGLGRVITGYEVKHNNWTLLGRGNPQEPQAFYPMDGIHKISTGDKLA
ARCTYDSKGHHLPGHVYIGSTGKDEMCNFYIMYYRDANEPEVADAACSDQTTHDYS-LTF
PVDSDAPLKTKSSTHKIHETPATKSPDHKHSSKSHTVTKKPIQNNHKQ------------
--------ISTSPLKHEESNTHMTK-----------------------------------
---HKMPENPSQPSTSSVENHHHNS-----------QLMDNYKIVK--NWPKLDQDHL-G
--QLTGVALDSKGHVLLFHRGKRTWNINSFNENNEFLIDT--PIQEFTVLTLNANTGTV-
-IGRWGKNMFYLPHGLTVDHHDNI-------------------WLTDVGSHQ---VFKFP
SNGGSK-PL-----LVLGEKFVPNSDESHFCKPTAVAV-EKSGNFYVADGYCNSRIVK-F
TAKGKFVDEWGQ-----YGL------NK---GS---FDVPHSLALDEASHRLYIADRENS
RVQSLDTTTGLFDPPIY-----SQQF---ELIFAVDFNPHS-GLLHAINGNSYDKNG--P
-----VKGFTLRATDGHLLKTWP---SVKQH-----FTHPHDIISSAD--DVDLYVVEVG
PNKVWKLSKRKPFKLHDNKASFPAFCMLEHDTGPCRAAMPRWYFDAKARSCTRFIYGGCS
GNENNFASKRECEAKCTQIVNSNKQQGKDNSGHISEMTLNNLPSKQGKQEEDTKRTEVSS
SLPYHGNNTAKPMTL---------------------HETDDWRNAAGEDEGNESNLHAAA
VWRQHHNTSTNLTTPHLIEKNRQNSNDNISAGGMIPALVILSVLAVPIVFLLLISIALRI
RAYR------RDTRYK-----------ANRLLKTDNEGLAVGHTRGWLSYLNCFKRQTYG
FDKVNMAEFYSDSDSDGV----------------------
>gi|123889648|sp|Q1PRL4|LIN41_C	Gallus gallus
MASFPEA----------DFQVCPLCKEMCGSPAPLSSNSSTSSSSSQTSGSSGGGGSSCG
GAARRLHVLPCLHAFCRQCLEAQRHPAAGDALKLRCPICDQKVVISEPSGMDALPSSNFL
LSNLLDVVVVAAAADEQKNGRAAGSGPAAGSGAGGGGANNRHHGRPPPHRAAAAASSPAA
GSAAPSASSSSSSGGGGPAALLLRRPHSRQGEPRCSSCDEGNAASSRCLDCQEHLCDNCV
RAHQRVRLTKDHFIERFAAGPAAASAGPAAPLALSPPYPASPYNILSVFPERASYCQHHD
DEVLHFYCDTCSVPICRECTMGRHVGH---SFIYLQDALQDSRTLTIQLLADAQQGRQAI
QLSIEQAQAVAEQVE--MKAKV----------VQSEVKAVTTRHKKALEERECELL-WKV
EKIRQVKAKSLYLQVEKLRQNLNKLDNTISAVQQVLEEGRTIDILLAR------------
--------------DRMLAQVQELKNVRGLLQPQE---------------DDRIMFTPPD
QALYMAIKSMGFVS-SGAFAPLTKATGEGLKRALQGKVASFTVIGYDHD----GEPRLSG
GDMISAVVMGPDGNLF----GADVSDQQNGTYLVSYRPQLEGEHLVSVMMCNQHIENS--
------------PFKVVVKSGRSY-----------------------IGIGL--------
-------PG-----LSFGSE---GDSDGKLCRPWGVSV-DKEGYIIVADR-SNNRIQV-F
KPCGTFHHKFGT-----LGS------RP---GQ---FDRPAGVA-CDVSRRIVVADKDNH
RIQIFTFE-GQFILKFG-----EKGTKNGQFNYPWDVAVNAEGKILVSDTRNHRVQLFGP
--------------DGVFLNKYGFEGALWKH-----FDSPRGVTFNHE--GH-LVVTDFN
NHRLLVI-------HADCQSAR--------------------------------------
--------------------------------------------FLGSEGSGNGQFLRPQ
GVAVDQEGRI--------------------------------------------------
-------------------------------------------------------IVADS
RNHR-------------VQIFESNGSFLCKFGAQGSGFGQMD-----------------R
PSGIAVTPDGMIVVVDFGNNRI-LVF--------------
>gi|27374240|gb|AAO00999.1|	Drosophila erecta
------------------------------------------------------------
----------MHSTDSEKCQGSKSLAICCLLLHLLLSIR--------PAVAQTQSS----
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------------Q
RYLHNVDNSSNNNERLQQILKGSGAGSGATQL------NWPQPSKQTVLNVKTGLAKLNN
S-------------------------------YVYQNA----------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------WP--ANNVKLG
--AVTAVSFDQAGNVVIFHRVDRVWGQNTFDTRNQFQEKFRGPIRESTVLALEPATGKV-
-QYDWGKNLFYMPHGLTVDPEDNV-------------------WLTDVAMHQ---VFKFQ
PRGGDGKPV-----LTLGDAFQPGSGRK-FCKPTSVAV-LDNGDFFVADGYCNARILK-Y
SRKGELILSWGRNSFSGISY------DVAPKNF---FAIPHALTLVPELQLLCAADRENG
RVQCFSSNNGTFHSQYH-----NQLI--GDRIFSMAYTPAAGGQLVIVNG-PIAELGINP
EHYNEVHGFVLSMRSKQLVSKFG---PNNLE-----FQNPHDVAVTVD--GNEIYVAELN
PMRIHKFV---------HRSLA--------------------------------------
--------------------------------------------KPMSLSATKDSSNSAI
SRAVEIDQATPEAVH---------------------------------------------
-------------------------------HPSGKAILVASLMLLFAGSTFALALIFAQ
RRKRGCLPFGARSRRHAWEKS---------------DGFKLG---GLLDRDRN------G
FEKLDQQASDEEQETKTLASAQ---YA-------------
>gi|27806825|ref|NP_776373.1|	Bos taurus
MAG-FRS----LLVLLLVFPSGCVG---FRSPLSVFK-----------------------
------RFKETTRSFSNECLGTTRPVIPIDSSDFALDIRM-------PGVTPKQSDTYFC
MSVRLPMDEEAFVIDFKPRASMDTVHHMLLFGC-NM---------P-ASTGNYWFCDE--
GTCTDKANILYAWARNAPPTRL----------PKGVGFRVGGETGSKYFVLQVHYGD--I
SAFRDNHKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPPGGKVV-----NSDISCHY-K
KYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVSFGDILA
ARCVFTGEGRTEVTH--IGGTSSDEMCNLYIMYYMEAKHA-VSFMTCTQNVAPDIF-RTI
PPEANIPIPVKSDMVMM--HGHHKETENKDKTSLLQQPKREEEGVLEQGDFYSLLSKLLG
EREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDTRESAEQER-GNAILVRDRI
HKFHRLVSTLRPAE-SRVLSLQQPLPGEGTWEP---EHTGDFHVEEALDWP--GVYLLPG
--QVSGVALDPQNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNNAAV-
-LQSSGKNLFYLPHGLSIDKDGNY-------------------WVTDVALHQ---VFKLD
PKSKEG-PL-----LTLGRSMQPGSDQNHFCQPTDVAVDPDTGTIYVSDGYCNSRLVQ-F
SPSGKFITQWGEAS---LES------SPKP-GQ---FRVPHSLALVPPLGQLCVADRENG
RIQCFKTDTKEFVREIK-----HPSF--GRNVFAISYIP---GLLFAVNGKPYFEDQ-EP
-----VQGFVMNFSSGEIIDVFK---PVRKH-----FDMPHDIAASED--GT-VYVGDAH
TNTVWKFTSTE---KMEHRSVK--------------------------------------
--------------------------------------------KAGIEVQEIKESEAVV
ETKMENKPASSELQK---------------------------------------------
--------------------IQEKQKLVKEPGSGVPAVLITTLLVIPVVVLLAIALFIRW
KKSR---AFG-DSERK-LEAS--SGRVLGRLRGKGGGGLNLG---NFFASRKGYSRK--G
FDRLSTEGSDQEKD-EDASESE-EEYSAPPPAPAPSS---
>gi|125809766|ref|XP_001361231.	Drosophila pseudoobscura
------------------------------------------------------------
------MHSTNSH-------------------------RR-------WSVIFLLATSFLQ
HTLS--------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------ESQSSPRYLQ
NIDISNNASINNNERLQQILKGAGAGSTQI--------NWPQRSKQATPDVKTELAKLNT
T-------------------------------YIYQNA----------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------WP--ANNVKLG
--AVTAVSFDKAGNVVIFHRVDRIWSQDTFDQGNQYREKYRGPIRESTVLALEPATGRV-
-QYDWGKNFFYMPHGLTVDPEDNV-------------------WLTDVAMHQ---VFKFA
ARGAGNKPL-----LTLGVAFQPGSGKK-FCKPTSVAI-LENGDFFVADGYCNARILK-Y
SKAGELILTWGQNSFAGVSY------DVAPQNY---FAIPHALTLVPELELLCAADRENG
RVQCFYSSNGTFHSQYH-----NQLI--GDRLFSMAYTPAAGGELVIVNG-PNAELGFHP
DHYNEVHGFVMSMRNRQLVSKFG---PNNLE-----FKNPHDVAVTAD--GNEIYVAELN
PMRIHKFL---------HKSLA--------------------------------------
--------------------------------------------KP-MSLSATKDAQSIS
GVPAEAPATGADASQ---------------------------------------------
---------------------------TTRHHPSGKAVLVASLMLIFAGSTFALALLMAR
RRKRGCLPFGARSRRHAWEKA---------------EGFKLG---GLLDRDRN------G
FEKLDQQASDEEQE----TLASGAPYA-------------
>gi|115640661|ref|XP_784943.2|	Strongylocentrotus purpuratus
MIKRPEA-----LIAQMILKNTCAML----------------------------------
------KLLLSEMHILVSCVLLYNPTSSSAPHPLLLILCS-------SSSAPHPLLLILC
SSSSAPHPLLLILLNFEPRASMKTIHHMLVYGCTDI---------P-NNEETVGACHG--
SPCLGKSNILFGWARDAASPDI----------PQGVGFHVGGASGINYIMIQMHYGD---
--KLDHLKDV----------------------------------------HSDIACKYDS
SANIHPFAFRAHAHDLGKVITGYLIRNGEWTVIAKGSPKWPQAFYPIGESYTIQPGDILA
ARCTYDSD-KDIATY--AGGTHNDEMCNLYLMYYTDATRG-EAFQECGRPAPGSFF-SSA
PPGYNT-VPSLPTSSQPETHSRNRPAPVDTWDPYYDYANQQGYDKDGQ------------
------------SYPQEGSNVDYVSPSVEDVGGGGGRGGGGRGGEDRERPEGTPKPVDNI
PDTDKTSSQASDGDATQAAPIIAPGNGDTVTQPPTSNKMQSFTVSDVDGWPSSGSGVTLG
--QVSGIAVDSAGNVHIFHRASRPWDIHSFQGDV-FTQSNQGPIINNTNIKYDSNTGKV-
-LSQWGANQFFLPHGLSIDHEDNI-------------------WLTDVAMHQ---VFKYP
PGGAGT-PL-----LTLGTKLEPGDDKNHFCKPSDVTVDPKTGNFFVSDGYCNARVMK-F
SPEGKLLLQWGHQL-KGITM------DLLPVGQ---FNLPHCITMVSDKNQVCVADREAG
RIQCFSADSGDFTKQFN-----LPEF--GGRLYAVAYSSASGGLLYAVNG-PSNGVK--P
-----VQGFALNYTSTEILRMWE---PHSQK-----FEKPHDIACTPD--GKLVYVAEIG
PNKVWKFTTNA---GNSTHFTP--------------------------------------
--------------------------------------------VAG----ETQATNTSL
NERLNGFTSDSSLGT---------------------------------------------
------------------------------------TTIIVAVLAVPILLMLLVAVAIRL
HAQG---HFRLNKKRR-------------NYKVSAGDKFSLG---SLLHKRN-------G
FSQVATDDSDPDAA-QWSEESDIEEYSILNNTKRTQNL--
>gi|125828481|ref|XP_699436.2|	Danio rerio
------------------------M---YR-----FK-----------------------
------RFQENSFTDPNDCSRTRQPFVMSSPYNFSLDIRL-------PGVVPTESDSYYC
MAVPVPTSREAYIVDFVPHASMDTAHHMILYGC-KT---------P-YATQGYWDCGKEL
GTCRDQAKIMYAWARNAPPTKL----------PKDVGFKVGGDTRINYFVLQIHYGD--V
NNFRDHHRDCSGLSLRMTSKPQPFIAGMYLMMSVDTLIPPGKKVT-----NADIACTY-T
SSPMYPFAFRTHTHSLGKVVSGYRVRNGQWTQIGRQSPLLPQAFYPATNTIDVKDGDILA
ARCVFTGEGRTTTTQ--IGGTSNDEMCNFYIMYYMDNTHA-VPYMNCRDDGSSELF-RNI
PSEANIPIPVRPDHMMSMKHESSPQKDAVE----LQEPKR-DEEVQDQGDLYSLLSKLLG
EREDHVRIHKYKPSEAARAQTLLLAEIDSIMQKKDLGRP----RLGYKTNEDAILARDRV
HKFHQLESTVSPWR-SRTVPARLPTTGAAQRDQ---Q---GAHLVEVSDWP--EADLQLG
--QVSGLALNSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQSTILLVDSVKGKV-
-LKASGKNMFYLPHGITTDHDDNY-------------------WVTDVALHQ---VFKLS
GNGKDQ-QL-----LVLGEAFEPGSDKKHFCQPTDVAVDPVTGNVYVSDGYCNSRILQ-F
SPEGKYISHWGADQRKSALS------SALP-GRRVPFRIPHSLTFLPDKRELCVADRDNG
RIQCFMADTGEFVKEIK-----KDVF--GGEVFAIAYSPAQGGLLYAVNGEPPYGQA-AP
-----LQGFVINYSSKEILDSFS---PDTQV-----FKLPHDIVVTAD--GT-VFVGDAA
ADSVMKFIQSA---KAEHRSVK--------------------------------------
--------------------------------------------KGGIEVQEIEETETFV
QAKLKPLPKIPPHYV---------------------------EAAVQKIQEVSPHQQPLA
APKEKEPPQSVANHSPESVANKSPESVANQSAQNVSPAVITSLLLVPLVSVIAIGVFIRW
KKSR---MYSDDCQVK-LEPSGSAGGILGKIRGKAAGSLNLG---NFFATHKGYTRH--G
FDRLSTEGSDMEKDDEDATDSENEEYSAPPPPISSS----
>gi|114600988|ref|XP_001136576.	Pan troglodytes
MAGRVPS-----LLVLLVFPSSCLA---FRSPLSVFK-----------------------
------RFKETTRPFSNECLGTTRPVVPIDSSDFALDIRM-------PGVTPKQSDTYFC
MSMRIPVDEEAFVIDFKPRASMDTVHHMLLFGC-NM---------P-SSTGSYWFCDE--
GTCTDKANILYAWARNAPPTRL----------PKGVGFRVGGETGSKYFVLQVHYGD--I
SAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVV-----NSDISCHY-K
NYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVSFGDLLA
ARCVFTGEGRTEATH--IGGTSSDEMCNLYIMYYMEAKHA-VSFMTCTQNVAPDMF-RTI
PPEANIPIPVKSDMVMM--HEHHKETEYKDKIPLLQQPKR-EEEVLDQGDFYSLLSKLLG
EREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDAREGAEHER-GNAILVRDRI
HKFHRLVSTLRPPE-SRVFSLQQPPPGEGTWEP---EHTGDFHMEEALDWP--GVYLLPG
--QVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAV-
-LQSSGKNLFYLPHGLSIDKDGNY-------------------WVTDVALHQ---VFKLD
PNNKEG-PV-----LILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQ-F
SPSGKFITQWGEES---SGS------SPLP-GQ---FTVPHSLALVPPLGQLCVADRENG
QIQCFKTDTKEFVREIK-----HSSF--GRNVFAISYIP---GLLFAVNGKPHFGDQ-EP
-----VQGFVMNFSNGEIIDIFK---PVRKH-----FDMPHDIVASED--GT-VYIGDAH
TNTVWKFTLTE---KLEHRSVK--------------------------------------
--------------------------------------------KAGIEVQEIKEAEAVV
ETKMENKPTSSELQK---------------------------------------------
--------------------MQEKQKLIKEPGSGVPVVLITTLLVIPVVVLLAIAIFIRW
KKSR---AFGADSEHK-LETS--SGRVLGRFRGKGSGGLNLG---NFFASRKGYSRK--G
FDRLSTEGSDQEKE-DDGSESE-EEYSAPLPALAPSSS--
>gi|56845|emb|CAA42210.1|	Rattus norvegicus
MAGRARSGLLLLLLGLLALQSSCLA---FRSPLSVFK-----------------------
------RFKETTRSFSNECLGTIGPVTPLDASDFALDIRM-------PGVTPKESDTYFC
MSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGC-NM---------P-SSTGSYWFCDE--
GTCTDKANILYAWARNAPPTRL----------PKGVGFRVGGETGSKYFVLQVHYGD--I
SAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGEKVV-----NADISCQY-K
MYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILA
ARCVFTGEGRTEATH--IGGTSSDEMCNLYIMYYMEAKYA-LSFMTCTKNVAPDMF-RTI
PAEANIPIPVKPDMVMM--HGHHKEAENKEKSALMQQPKQGEEEVLEQ------------
------------------------------------------------------------
----------------------------------------DFHVEEELDWP--GVYLLPG
--QVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNNAEI-
-LQSSGKNLFYLPHGLSIDTDGNY-------------------WVTDVALHQ---VFKLD
PHSKEG-PL-----LILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQ-F
SPSGKFVTQWGEES---SGS------SPRP-GQ---FSVPHSLALVPHLDQLCVADRENG
RIQCFKTDTKEFVREIK-----HASF--GRNVFAISYIP---GFLFAVNGKPYFGDQ-EP
-----VQGFVMNFSSGEIIDVFK---PVRKH-----FDMPHDIVASED--GT-VYIGDAH
TNTVWKFTLTE---KMEHRSVK--------------------------------------
--------------------------------------------KAGIEVQEIKEAEAVV
EPKVENKPTSSELQK---------------------------------------------
--------------------MQEKQKLSTEPGSGVSVVLITTLLVIPVLVLLAIVMFIRW
KKSR---AFG----------------------GKGSGGLNLG---NFFASRKGYSRK--G
FDRVSTEGSDQEKDEDDGTESE-EEYSAPLPKPAPSS---
