>gi|118601892|ref|NP_001073117.	Bos taurus
------------------------------------------------------------
-------------------------------------MASKCPK---------------C
D---------------------------------------------KT-VYF-AEKVSSL
GK-DW--HRFCLR-----------CEHCSKTLTP--------G----GHAE-HDGKPF--
---------CH-KPCYAT-LF---GPK----------------------------GVNI-
-----------GGAGSYI--YEKPSAEKPQVTGP--------------------------
-----------------IEVPVARTEERKA---SGPPKGP---SKASSVTTFTGEPNM-C
--PRCNKRVYFAEKVTSLGK---DWHRPC------LRCERCGKTLTPGGHAE-HDGQPYC
HKPCYGILFGPKG-------VNTG-A-----VGSYIYDKDPEGKAQP-------------
-----------------
>gi|24762552|ref|NP_726418.1|	Drosophila melanogaster
------------------------------------------------------------
----------MA------------------------PDGEGCPR---------------C
G---------------------------------------------GA-VFA-AELQLSK
GK-MY--HRKCFN-----------CARCTRPLDS--------V----LACDGPDDNIY--
---------C--KLCYAK-LF---GPK----------------------------GVGY-
-----------GHTPTLV--------STNYEYTP--------------------------
-------------------------------------------SCWGTIDRNGQKSENGC
--PRCGFMVFAAEQVKSAKN---VWHKLC------FYCMECRKYLDSTNLNDGPDGGIYC
-RSCYAKFYGPKG-------VGYGIG-----AGTLTMA----------------------
-----------------
>gi|56759118|gb|AAW27699.1|	Schistosoma japonicum
------------------------------------------------------------
------------------------------------MPSEICPK---------------C
Q---------------------------------------------KA-VYA-AERKIAG
GK-AW--HSMCLK-----------CGLCNKMLDS--------T----TVAE-HEGEVY--
---------C--KTCHGR-KF---GPK----------------------------GYGF-
-----------GGGSGAL----NMDTGTHVGNKE--------------------------
-----------------TE----------------MSNKP---TAAGMGGKVISPEEGGC
--PRCGKRVYDAEKANWMSKWTPIFIKHV------SDAKFVGNHLIQLRCAHKKKKKKFT
VKLVMEKTLGPKG-------FGFGQG-----AGALNMG----------------------
-----------------
>gi|114607533|ref|XP_001137772.	Pan troglodytes
------------------------------------------------------------
-------------------------------------MSWTCPR---------------C
Q---------------------------------------------QP-VFF-AEKVSSL
GK-NW--HRFCLK-----------CERCHSILSP--------G----GHAE-HNGRPY--
---------CH-KPCYGA-LF---GPR----------------------------GVNI-
-----------GGVGSYL---YNPPTPSPGCTTP--------------------------
-----------------LSPSSFSPPRPRTG----LPQGK---KSPPHMKTFTGETSL-C
--PGCGEPVYFAEKVMSLGR---NWHRPC------LRCQRCHKTLTAGSHAE-HDGVPYC
HIPCYGYLFGPKG----------GQPHPRHWDGMYIPKVWHVHGLWVCVDNFPCG-----
-----------------
>gi|89242514|gb|ABD64615.1|	Oncorhynchus mykiss
-----------------------------------MPL----------------------
------------------------------------GGGNKCGC---------------C
R---------------------------------------------KT-VYF-AEEVQCE
GK-FF--HKCCFL-----------CMACKKNLDS--------T----TVTC-HVDEIY--
---------C--KSCYGK-KY---GPK----------------------------GYGF-
-----------GGGAGTL----SMDTGAHLGIRP--------------------------
-----------------EEPAAHC-----------PTNNP---NASKLATKFGSSDV--C
--PRCAKAVYSAEKVLGGGN---SWHKSC------FRCAKCGKGLESTTVAD-KDGEIYC
-KACYAKSFGPKG-------FGFGQG-----AGALAHAQ---------------------
-----------------
>gi|76781465|ref|NP_001029098.1	Rattus norvegicus
-------------MASQRHSGPSSYKVGTMSEKFDCHY----------------------
----------CRDPLQGKKYVQKDGRHCCLKCFDK-FCANTCVE---------------C
R---------------------------------------------KP-ISADAKEVHYK
NR-YW--HDTCFR-----------CAKCLHPLAS-ETFVSKDGKILCNKCATREDSPR--
---------C--KGCFKAIVA---GDQ----------------------------NVEY-
-----------KGTIWHKDCFTCSNCKQVIGTGS--------------------------
-----------------F-----------------FPKGEDFYCVTCHETKFAKH----C
--VKCNKAITSGG-ITYQDQ---PWHAEC------FVCVTCSKKLAGQRFTA-VEDQYYC
-VDCYKNFVAKKCAGCKNPITGFGKG-----SSVVAYEGQSWHDYCFHCKKCSVNLANKR
FVFHNEQVYCPDCAKKL
>gi|4587499|gb|AAD25742.1|AF134	Homo sapiens
-----------------------------MRLTLLCCT----------------------
----------WREERMGEEG----------------SELPVCAS---------------C
G---------------------------------------------QR-IYD-GQYLQAL
NA-DW--HADCFR-----------CCDCSASLSH-------------QYYE-KDGQLF--
---------C--KKDYWA-RY---GES----------------------------CHGCS
EQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTVVTPVIE
QILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGC
MSPDVKNSIHVGDRILEING---TPIRNVPLDEIDLLIQETSRLLQLT-----LEHDP--
-HDTLGHGLGPETSPLSSPAYTPSGE-----AGSSARQKPVFARTWVALSPSA-------
-----------------
>gi|47207468|emb|CAF93748.1|	Tetraodon nigroviridis
------------------------------------------------------------
--------------------------------------ASKCPK---------------C
D---------------------------------------------KT-VYF--------
--------VVKQR-----------CSFCLLIVPP--------S----CLWQ-HDGTPY--
---------CHTNRATPP-SL---GPKVALSPPQFPPRLSAASFLVSVLFLCLYRGVNI-
-----------GGAGSYV--YDDPVNEAPAAVSM--------------------------
-----------------ETSRNPEEEKRA------PARGP---VKAASFSSFSGGPNI-C
--PRCNKTVYFAEKVSSLGK---NWHRPC------LRCERCSKTLAPGSHAE-HDGQPYC
HKPCYAVLFGPKG-------VNTG-G-----VGSYIYDDPAAETQP--------------
-----------------
>gi|149639029|ref|XP_001507066.	Ornithorhynchus anatinus
----------------------MLLLTGLPGSSLDKAR----------------------
----------VQ------------------------VLIQTCQE---------------R
S---------------------------------------------RE-MDKELIGLETT
GKADWISSTVASR-----------SNWTGQTVNS--------GLEGLCPCE-HVGKPY--
---------CH-KPCYAT-LF---GPK----------------------------GVNI-
-----------GGAGSYI--YEKPPADEALVTGP--------------------------
-----------------IE-HVARAEERKVNTASNPPRGP---SKASSVTIFTGEPNM-C
--PRCGKRVYFAERVTSLGK---DWHRPC------LKCEKCNKTLTSGSHAE-HEGKPYC
NHPCYAALFGPKG-------FGRG-G-----AESHTFK----------------------
-----------------
>gi|45383924|ref|NP_990539.1|	Gallus gallus
-----------------------------------MPN----------------------
----------W-------------------------GGGNKCGA---------------C
G---------------------------------------------RT-VYH-AEEVQCD
GR-SF--HRCCFL-----------CMVCRKNLDS--------T----TVAI-HDAEVY--
---------C--KSCYGK-KY---GPK----------------------------GYGY-
-----------GQGAGTL----NMDRGERLGIKP--------------------------
-----------------ESTPSPHR----------PTTNP---NTSKFAQKFGGAEK--C
--SRCGDSVYAAEKVIGAGK---PWHKNC------FRCAKCGKSLESTTLTE-KEGEIYC
-KGCYAKNFGPKG-------FGYGQG-----AGALVHAQ---------------------
-----------------
>gi|73964565|ref|XP_855529.1|	Canis familiaris
-----------------------MCSSPVGSRSLPCHW----------------------
----------TQSTPSWQLGC---------------YCAAPYPPGGSQ-----GRPLPPC
GPVLKLASVAWPWRPWAAAATAIAGQQEPWEREWGWQGTQDPGPRGQSGLGERAEKVSSL
GK-DW--HKFCLK-----------CERCNKTLTP--------G----GHAE-HDGKPF--
---------CH-KPCYAT-LF---GPK----------------------------GVNI-
-----------GGAGSYI--YDKPSAEGPQVTGP--------------------------
-----------------IEVPVVRAEERKA---SGPPKGP---SKASSVTTFTGEPNM-C
--PRCNKRVYFAEKVTSLGK---DWHRPC------LRCERCGKTLTPGGHAE-HDGQPYC
HKPCYGILFGPKG-------VNTG-A-----VGSYIYDRDPEGKAQP-------------
-----------------
>gi|123122184|emb|CAM26737.1|	Mus musculus
MTFYVAFLALKLIWMLSSPTGPSSYKVGTMSEKFDCHY----------------------
----------CRDPLQGKKYVQKDGRHCCLKCFDK-FCANTCVD---------------C
R---------------------------------------------KP-ISADAKEVHYK
NR-YW--HDNCFR-----------CAKCLHPLAS-ETFVSKDGKILCNKCATREDSPR--
---------C--KGCFKAIVA---GDQ----------------------------NVEY-
-----------KGTVWHKDCFTCSNCKQVIGTGS--------------------------
-----------------F-----------------FPKGEDFYCVTCHETKFAKH----C
--VKCNKAITSGG-ITYQDQ---PWHAEC------FVCVTCSKKLAGQRFTA-VEDQYYC
-VDCYKNFVAKKCAGCKNPITGFGKG-----SSVVAYEGQSWHDYCFHCKKCSVNLANKR
FVFHNEQVYCPDCAKKL
>gi|91081469|ref|XP_976171.1|	Tribolium castaneum
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------------MLAR
GR-GW--HRICFR-----------CNNCSRWLDS--------T----SHCDGPDGEVY--
---------C--RACYAQ-RF---GPR----------------------------GI---
-----------GHAGGTFLGLMCDALDLKWQSDA--------------------------
-----------------------------------APK-----TTVIDTACIKAPPGQGC
--PRCGGVVFAAEEVLAKGR---PWHRKC------FKCKDCTKTLDSIIACDGPDSDVYC
-KTCYGKKWGPHG-------YGFACG-----SGFLQTDGLT-------------------
-----------------
>gi|149755745|ref|XP_001490534.	Equus caballus
-------------MASHRHSGPSSHKVGTMAEKFDCHY----------------------
----------CRDPLQGKKYVQKDGRHCCLKCFDK-FCANTCVE---------------C
R---------------------------------------------KP-IGADAKEVTYK
NR-YW--HDTCFR-----------CAKCLHPLAS-ETFVAKDNKILCNKCTTREDSPK--
---------C--KGCFKPIVA---GDQ----------------------------NVEY-
-----------KGTVWHKDCFTCSNCKQVIGTGS--------------------------
-----------------F-----------------FPKGEDFYCVTCHEAKFAKH----C
--VKCNKGLVKAP----------VWWP--------------------------MKDNP--
-----------------------GTT-----TASTAKNAP--------------------
-----------------
>gi|8439529|dbj|BAA96552.1|	Branchiostoma belcheri
-----------------------------------MPF----------------------
----------TA------------------------PQAPKCPK---------------C
G---------------------------------------------KS-VYQ-AEERLAA
GR-SF--HNTCFK-----------CTMCNKMLDS--------T----TVAE-REDSLF--
---------C--KTCYGK-KF---GPK----------------------------GVGF-
-----------GQGAGAL----GMDSGERFGNKP--------------------------
-----------------TESTAPMTGAAY------LNVGKS--SEPAKPSKYGSTAEK-C
--PRCGGSVYPAEKVIGAGK---SWHKVC------FKCSACNKALDSTNVCD-REGEIYC
-KACYARGFGPSG-------LRAGQG-----AGVRTQTKAPSASVI--------------
-----------------
>gi|125808857|ref|XP_001360895.	Drosophila pseudoobscura
------------------------------------------------------------
-----------------------------------APEGEGCPR---------------C
G---------------------------------------------GA-VFA-AELQLSK
GK-MW--HRQCFS-----------CARCHRPLDS--------V----LACDGPDDNIY--
---------C--KLCYAK-LY---GPK----------------------------GVGY-
-----------GHTPALV--------STSYEYTP--------------------------
-------------------------------------------TSWGQLNRCGGQSEDGC
--PRCGYIVFAAEQMKSKNS---IWHKLC------FYCSGCRKYLDSTNLNDGPDGNIYC
-RSCYGKNYGPKG-------VGYGIG-----AGTLTMA----------------------
-----------------
>gi|62751476|ref|NP_001015811.1	Xenopus tropicalis
------------------------------------------------------------
-------------------------------------MTSQCPR---------------C
R---------------------------------------------AP-VYF-AEKVSSL
GK-NW--HRFCLK-----------CELCNKILSA--------G----GHAE-HDGQPY--
---------CH-KPCYGA-LF---GPK----------------------------GVNI-
-----------GGVGSYI-----YDTTPQISQNP--------------------------
-----------------VSPTLCVPNHSS------STNTKPATKAPAPMRTFAGETAL-C
--PGCGKPVFFAEKVMSLGR---NWHRPC------LRCQRCNKTLTAGGHAE-HDGLPYC
HVPCYGYLFGPKG-------VNIGD------VGCYLYDPLTETVN---------------
-----------------
>gi|109018946|ref|XP_001098252.	Macaca mulatta
MSLARARRFPRWRRQGAQWDRSTSAGHPHSRRLLPPPLPAGQSWGLGGQHRRASRHDISP
GVVQCAKPTGWRGPGHAFPGAEQNGAQAGRTQ----PPLPRAPAARAP-----PSQLPEC
R------------------------------------------------TGEEARNVGCV
RRRFTLPKRFSAKATASINPASCAVMVCKKNLDS--------T----TVAV-HGEEIY--
---------C--KSCYGK-KY---GPK----------------------------GYGY-
-----------GQGAGTL----STDKGESLGIKH--------------------------
-----------------EEAPGHR-----------PTTNP---NASKFAQKIGGSER--C
--PRCSQAVYAAEKVIGAGK---SWHKSC------FRCAKCGKGLESTTLAD-KDGEIYC
-KGCYAKNFGPKG-------FGFGQG-----AGALVHSE---------------------
-----------------
>gi|82408372|gb|ABB73031.1|	Mytilus edulis
-----------------------------------MPF----------------------
----------KP------------------------PERSICPA---------------C
G---------------------------------------------SA-VYA-AEEKLGA
GK-KW--HKMCFK-----------CGLCNKLLES--------T----TVAE-HEGRVY--
---------C--KGCHGK-KF---GPK----------------------------GYGF-
-----------GQGAGAL----SMETGSQFGNKD--------------------------
-----------------SEMSN-------------RPREQ-------HVGPSNSGPGPHC
--PRCGKTVYEAERAIGLTD---AWHKGC------SKCKECNKAVDSTTLCR-HEIEIYC
-KGCYAKNFGPHG-------FGVGLL-----AK---------------------------
-----------------
>gi|40363543|ref|NP_954687.1|	Danio rerio
-----------------------------MASRSNCFY----------------------
----------CREDLSGKKFVRKDEKQVCVRCFDK-FCANTCTE---------------C
R---------------------------------------------RT-ISTDSKELHHK
GK-YW--HSDCFR-----------CAKCYKNLAK-ESFTSKDDRILCGTCSSREDAPR--
---------C--HGCYKPILP---GTE----------------------------NVEY-
-----------KGNSWHDECFKCYQCQKPIGNKS--------------------------
-----------------F-----------------ITKNNNVYCSPCHEKKFAKQ----C
--ACCKKPITTGG-VNYQDQ---PWHSEC------FVCSSCRKPLAGTRFTS-HEEKVYC
-VDCYKSTVAKKCSGCQNPITGFGKA-----TNVVNYEGGSWHDYCFNCKKCSLNLADKR
FVAHSGHIYCSDCSKKL
>gi|126310066|ref|XP_001365232.	Monodelphis domestica
------------------------------------------------------------
-------------------------------------MSWTCPR---------------C
Q---------------------------------------------QP-VFF-AEKVSSL
GQ-NW--HRFCLK-----------CERCHNVLAA--------G----GHAE-HNGKPY--
---------CH-KPCYAV-LF---GPL----------------------------GIKA-
-----------GGVGSYMEDLPHPPTVTPITTMP--------------------------
-----------------LTAGSFSPPRSRT----GPPQAKRSRRSPTQVKTYAGETSL-C
--PGCGNPVYFAEKVMSLGR---NWHRPC------LRCQRCRKTLTAGSHAE-HDGFPYC
HIPCYGYLFGPKG-------VNIG-D-----VGCYIYDSLELKSD---------------
-----------------
>gi|147901743|ref|NP_001079213.	Xenopus laevis
-----------------------------------MPI----------------------
----------L-------------------------GGGAKCGA---------------C
G---------------------------------------------KS-VYH-AEEIQCN
GR-SF--HKPCFI-----------CMACRKALDS--------T----TVAA-HESEIY--
---------C--KSCYGR-KY---GPK----------------------------GYGY-
-----------GQGAGCL----STDTGERFGIEV--------------------------
-----------------AESHPARG----------SPTTP---HSSKLAAKFGATEK--C
--PRCQKSVYAAERVMGGGQ---AWHKTC------FRCAFCGKSLDSTTVTE-KEGEIYC
-KVCYAKNFGPKG-------IGFGGL-----TQVEQKET---------------------
-----------------
>gi|118792266|ref|XP_551885.2|	Anopheles gambiae
---------------------------MSERKVLNKYY----------------------
----------PPD-----------------------FDPSKIPR---------------V
K---------------------------------------------LP------KNRQYT
VR-LM--APFNMR-----------CVTCGEYIYK--------GKKFNARKEDVENEDYLG
IRIYRFYIKC--TRCLQEISFKT-DPR----------------------------NTDY-
-----------EIEAGATRNFMALKLAEEQARRE--------------------------
-----------------EEEAREEEATNPMKLLENRTQHTDAKPANGPKAKDGKG----C
--TRCGYAVYEAEKMLSKNR---IWHKRC------FSCFDCHKSLDSTNLNDGPNGEIYC
-RGCYGRNYGPRG-------VGFGMG-----AGALTMA----------------------
-----------------
>gi|31982445|ref|NP_031818.2|	Mus musculus
-----------------------------------MPV----------------------
----------W-------------------------GGGNKCGA---------------C
G---------------------------------------------RT-VYH-AEEVQCD
GR-SY--HRCCFL-----------CMVCRKNLDS--------T----TVAI-HDEEIY--
---------C--KSCYGK-KY---GPK----------------------------GYGY-
-----------GQGAGTL----NMDRGERLGIKP--------------------------
-----------------ESAQPHR-----------PTTNP---NTSKFAQKYGGAEK--C
--SRCGDSVYAAEKIIGAGK---PWHKNC------FRCAKCGKSLESTTLTE-KEGEIYC
-KGCYAKNFGPKG-------FGYGQG-----AGALVHAQ---------------------
-----------------
