>gi|55926096|ref|NP_001007523.1	Xenopus tropicalis
----------------------------------MGNAAGSLDMFQARDTRGQSTSGTPP
QKQKEGTPSKL-----------------PRPNSVELEQRFNV------------VLNAMN
LP------------PDKIQVLRQYDQ-DKKWELVCDQERFQVKNPPA---------AYIQ
KLRSYLDTGG---ISRKFKRRV--QESTQVLRELEIS-----LRTN-HIGWVEEFLSPEV
G-----GLDALVEYLSYAQGSCPIDTECSDNGTPEKSKSLQRSLEDINKSSSSPSPTNTP
SRSR------NLTARYNLHSRSTMRNTKHANM--KDDVHVCIMCLRAIMNYQSGFS----
-----MVMSHSSCV-NKITL-SLSNKNPRTKA-----------LVLELLAAVCLVRG---
-------GHELILSA----------------FNYFMEMCGEGARFEK--LMEYFRTEDS-
---------NI---------DFMVACMQFINIVVHSVKN--------------------M
NFRVFLQYEFTLLGLDEYLEILKNTESERLQVQIQAYLDNIFDVNSLLE-----------
---------------DTDTKNEMLEHVEDLQEHLTRVT--EKLQLTENEYVRR-------
------------VAELEKQLDQCRREMSSAKEKLVVQAPQVTQNIV--------------
--------------------------QRTELVKRSVLWVEPAGDTCTEEISDNTFTSDLP
SAASTP-------------------------PLSPSAIRITLISPSVTSTDALSSRGNSP
RSTTP---------------------------------PALLPSLPESS----EIFSIP-
-----APSPVPSSEDSSDTALKASKVNPVPSPPSIIDQTQTSN-----------------
-------------------AQSLSRTHDESPPP-------PPPPP---LPSIAE----IP
PPP------PLPMSADVPPPPPL-PELSGI-----------PPPPPLPMGEQ----GAPP
PPPSMGA--PGV----------PPPPPPPPSGFGPAPPPPPGGQPA--------------
-ATLNTGVSIKK--------------PIQTKLRMQVLNWVA--L-----------KPTQI
-----------NGTVFTHL----NDEKVLQELDMSDFEENFKTKAQGPSQTTF--SM--K
VKAAQNQPNKVSLIETNRAKNLAITL--RKGGLSPEAITSAIQKYDMQ-AFNMDFLELLA
RFLPTDWER-QQISRYCRDQKPLD---DLTAEDRFMVHLCSIPRLAERVNTMTFMANFPD
MASRLKPQLDALIAASMSIKSSDKLKGILELVLAFGNYMNSSKR--GAAYGFRLQSLDVL
LETKSTDRK-QTLLHYMIRVICEKYSHLSN-----FY-CDLNFMDKAATVSLDSVL----
---ADVKSLQAGMEQVQKEF------TKQDDCLILKD----FIKSNMDSLKQLSADAKTA
QEA-------------------------YDAAVGY-------------------------
-----------FGE-----NAKTTPPSTFFPI---FVRFIKAY---KQAEQDLETWKKQE
SAVQEAKPE-----------------------------------TAGKQAPQSPVVKSLR
PQVN--------LMAELNKKLQTKEPRVYEQNWAIE----------------DIITD---
-----------LRNQ---------------------------------------------
------PYRRTDVGRRSGK------------KQNSGQPLNTPDIQV--------------
------
>gi|118785095|ref|XP_314313.3|	Anopheles gambiae
------------------------------------------------------------
------------------------------------------------------------
------------------KLLSSEGR-ELRRVLFSLKQIFQEDKDLVHGFVAHGGLNCLV
QIGSEADQNY---QNYILRAL---GQVMLYVDGMNGV-----MKHSPTIQWLYSLIASRY
RLVVKTALKLLLVFVEYCEGNCYLLVSAIRFMDTAR------------------------
----------GVVPWNNIM--RLLKDYENADT---ELLIYATSLINKTLSGLSDQD----
-----SFYDESDFL-EQQGMEGIIQRYMSRPG-----------TDLDLLDQLQLYESVLR
FEDGECDGIRIPDNT--VRKTLRYR------STGNDTTDRRKSRRHS--TGTAPPQPPS-
----------------------RTPCTRHRPLPGQRQQDEDSSSSA--------------
----HSGDHLPGSGYHD-PSRDTTGVTPGLRRRRERAERQMNLMREQQELGQFPNGIVPT
GEDGNNATNVGYHAGHRNGASNYRRQSGGTGPLTNSSLLAPPTIHEEDKLQLRLNGGLTS
SVILHKQQPSNHIEHTNGTGHANGHGAANATSQLDSVEYRNSRNLL------LKKHGTSG
GVSMAPVSISNGTAPDRYKADLNGNSVRSTRTCTGVLSEQDDENKSPN-IKTQMMGLSVA
YGKQLANGKDSSDTSYHRRSATSTAYERSNGSLNGGHVEPKGQDLPPVPGKPLSLELLKV
CQMFQ---------------------------IRSFLYLSRFLPFLAES----DNEDKK-
---LILQLKKDHTVKDLTQKLSCLPLSPQEE-----KPQNRIGDMS-----GLISKAKEG
LAKSKSNKDISR-SPS---VDNDIKKLANGEPKK-----SENELH---WEEIVK----NM
TRKLSLCDLDFTDLTSDDDKDLL--APRGFGGA--------VPPPPPPSGML--MNGMPP
PPSMM-----------------RPPP-----TNLVPLSGSMMNGN---------------
-GLPQPNSLDGSA-------------AIKKNKKTVKLFWKE--V-----------RDDMI
PAVI-------QRTIWDEL-----PEAIVDTQKLEHL---FESRAKDL-------MT--K
KQQELNKNKEIIVLDHKRSNAINIAM--TKLP-PPRAIKAAILKMDST-VVTREGIDKLL
NMLPTDEER-CKIQEAQMLNPEL----PLGTAEQFLLTLSSISELGARLKLWAFKLDFEN
IEKEIAEPLNDLKQGIELLKSNLTFKCILSTLLNIGIFLNG-----APVKGFQIDYLAKV
PEVKDTVHK-HSLLHHLCHMVMESQANTTD-----LY-SEIGPITRASKADFNELA----
---HNIVYLE---TECKASWDRLKLIGKHDTAPHLKQKLIDFLADCAERIIILDIVHRRV
LNR-------------------------YRKFLLW-------------------------
-----------LGVPQ--LRIAESRPNEFCRI---VSEFALEY---RTTRERVQQQIEKK
ANHRERNKTRGKLIVDVAKLKTQ---------------------EDRADDELRTLLGTPT
KGPGGD---EVEMSGTLTWRRRRG----DATASPVTLMNS-HFTDGD-----DEILE---
-----------SLVK--TATKTATPRP-MQRERKRTRQADRK------------------
------SLRRTLKNGLSEE------------EKQHVASLIKGY-----------------
------
>gi|108869577|gb|EAT33802.1|	Aedes aegypti
-----------------------------------------------MLDPISINRLRHG
QVEDDEPPEICVVEGVFSLQTL--TPTQPMPAVDELDSKFAE------------LVEELD
LTAPNKAAMLSLPPQKKWQIYCSRKS-PLDATDPSGAPLPGVNLPPSPEHYIERLKDMAV
QLKASSPDES---PSHEYSPKI--ESHTALFDALKTA-----LRTS--------------
------AHSFVIRFIELQ------------------------------------------
----------GLPALLELL--QALDIRVANSP----LHTSLIGCIKALMNNSTGRS----
-----HVLAHPTGI-DTIAR-SLAADNIKTKI-----------AALEILGAVCLVPG---
-------GHKKVLTA----------------MLNYQEYAAERVRFQG--IVNDLDKSTG-
-----AYRDDV---------NLKTAIMSFINAVLNYGPGQEN-----------------L
EFRLHLRYEFLMLGIQPVIDKLRKHENETLNRHLDFFEMV--------------------
---------------RNEDEKELARKFNHEHVDTKSAT--AMFDLLRRKLSHS-------
------TAYPHLVSLLQHML--LLPHTGPNAQHWLIFDRVVQQIVL--------------
-----------------------------------QQEERPSSEIDPD-SQDKTSESSLK
LQDPDIAPL----------------------QIDVKKIVKLLVKEEELVAARSRAEDLER
EN-----------------------------------------SEINGKL---AKKEQEL
DLRTQEKEDLETSLARMRERLEKESANLSQAVQRAMNAEMRAEDLQ-----HRFVSEQQE
-------------------RIRLERLVTEGS--------IPDDQK---VAGLQG----CN
GQV--------------------------------------SPPPPPPPCKL------PP
PPPPMMA---------------APPPPPAPGGLPKISNPNIANQP---------------
-APPKLDAPKKN--------------VPQPANPLKSFNWSK--L-----------PDSKL
-----------QGTVWSEL----DDTKWYNSIELESIDKLFSAYQKNGVANDGSIED--L
RLIGKNKTKILSVIDGRRAQNCTILL--SKLKMSDEEISKAILSMDSNEQLPIDMVEQLL
KFTPSAEER-ALLDEHSEDID------SLARADRFLYEISKIPHYEQRLRSLHYKKRFQL
TVSDLSPRIASVMEASREVARSRRLRKLLELVLALGNYMNRGAR--GNASGFRLASLNRL
ADTKSSAAKGTTLLHYLVQIIEKKFKDILF-----LE-EDLPHVKEASKVSLGEMD----
---KDITMLRAGLTEVNREIEFHRSSGVPQPGDRFLPVMSEFHAQASVRFTELEDQFQNM
KTR-------------------------FDRAVRL-------------------------
-----------FGE-----DGAVVQPDEFFGI---FDGFLSAL---MEAKQDNENFRRRH
EEEEKRARQEAELKK-----------------------------RTIERKSKEGLLNSVA
KNLG--------------LKSSKSSNGSANGGSPVAGGDPNNKGEFDDLI--SAL-----
-----------RTGD--VFGEDMAKFK-RSRKTRLGPATNGGSNTS--------------
------PPRSRNSIGREDS------------RERPVVTNRRQ------------------
------
>gi|125978112|ref|XP_001353089.	Drosophila pseudoobscura
----MIVKMEPDELITFRVQYLVDSDPLSACTAFPIPVRAPTYAFATTMPLATQIGTILR
LLNAPQSIDDAAIQVYKDGDYG--AYLDLESSLAEQTEEIEGLNASRKNS----LVVRTQ
LNVRVH--------SIIEKLLSSEGS-DLRRALFSLKQVFQEDKDLVHAFVALGGLNCLV
RVGNCADQNY---QNYILRAL---GQVMLYVDGMNGV-----MKHEPTMQWLYSLIASNY
RSVVKTALKLLLVFVEYAESNCYVLVSAIHAVDATQ------------------------
----------GTLPWSNIM--RLLKDYDNADA---ELVIYATSLINKTLAGLNDQD----
-----TFYDESDLL-EQQGMETVIQRYMSKPG-----------TDLDLLDQLQLYEAVLK
FEDGESDGQRLPQNS--MRKTQRY-------RPGSNTTERRKSRRHS--TDNSPAPITK-
--------------------VLATTLLRMTPTQGTLDEDSSGSTNS--------------
-------TEFSGGLFNEKKPRDGAGVTPGLRRRRERAERHKSFLKEQQEA----------
---------------AANGIFAALEQREGLGQIVTAIP--ATIQSGDSPPQSL-------
-------QHELPLQPCNNNISSNSNNDTPNNSLLLSPSKQLLSGSH--------------
--SISKFLTKKNLFRERNATVINGIMKNIQQTADSGYKKYENDANRLN---NYYTQMSQS
PKHQLQQQDPEGVLLSPKKSLNASGF-----DFTPVPLSSTPVKGDNPPEAEPLSPIQKP
MALAT--------------WWHAPIGSVATRTLTSTNPAVDTPTDLDSE----GKQQQQ-
--LLQLQLKRDHTVKDLTQKLSNLPTSPTQEPG---NRSAIVGDMS-----GLISKAKEG
LAKSKSKGEISR-------SSSVDQELKKSEPKK-----SENELH---WEELVR----NM
TRPLNLCDLDFTDLHDDDEKDVL-APRG-LGVG--------IPPPPPPFAGG----GGIL
PPPMMPP--APSL---------IPPP---MFGYGGSLTNSVNSSLN--------------
-GSVNGDLANGN-N------------TIKKNKKTVKLFWKE--V-----------REDLI
PQVV-------GKTIWDEL-----PNANVDTQKLEHL---FESRAKDL-------MT--K
KQQELNKSKEIIVLDHKRSNAINIAI--TKLP-PPRAIKAAILKMDAT-VVTREGIDKLL
NMLPTDEER-GKIQEAQLVNPEL----PLGSAEQFLLTLASISELGSRLKLWAFRLDFDN
SEKEIAEPLMDLKQGIEILRQNRTFRSILSTLLSVGIFLNG-----APVKGFQIEYLAKV
PEVKDTVHK-HSLLHHLCHMVMESSSDTSD-----LY-SEIGPITRASKADFTDLA----
---HNLTQLE---AECKASWDRLKVIAKHDCPPPLKQKLVDFLADCAERIIILQIVHRRV
MNR-------------------------YRKFLLW-------------------------
-----------LGMPQ--HSVAESRPNEFCRT---LSEFALEY---RTTRERVQQQLEKK
ANHRERNKTRGKLIIDMAKFKTK---------------------EDVADAELK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------
>gi|91079993|ref|XP_970849.1|	Tribolium castaneum
------------MSLTCRVQYLNDIDPFSYTTNFPDPARPPLHTFSVTLPLINQLAAVHR
LLKSPHRLDDAALQLYKDGDYG--SYLDLEASISEQQEEFEGFQSNKKNS----IVLRTQ
LSVRVH--------TIIEKLLTSEGR-ELRRALFSLKQIFQEDKDLVHEFVQNDGLSCLI
KVGSEADQNY---QNYILRAL---GQVMLYVDGMNGV-----MEHNQTIQWLYSLISSKF
RLVVKTALKLLLVFVEYTESNCLLLIKAIQAVDFAQ------------------------
----------GVLPWHNIM--KLLKDFDSADT---ELLIYATTLINKVLNGVPDQD----
-----TYYDQTDSL-EEQEIERIIQRYMSKPG-----------TDLDLLQQFQIYEAVLQ
YEDGEEGGTPIRHLDESIRKTLRTR------KSVSEANERRKSRRHS--TGTSPHPHPL-
---------------------LARNNNRSLQINVEDDESSSSQSSE--------------
-----INNSQLNGCYKDSNKATDAGVTPALRRRRERAERQRSFMR---------------
---------------EQQETVELLRAASQNEEDENENNLGNYTNALQQRIANR-------
----------KDITPLMNAVNKLDSEENLTKQPWILYDDSQQ------------------
------------------------------------------------------------
-------------------------------PIDENTENSNENERNVL------------
------------------------------------------------------------
-----LQLKRENTVKDLTQKLANQNILHSPSDE---NKPNRIGDMT-----GLISKAKEG
LAKSKS-------------KADVLKSPTTESPPKIEVKKSENELR---WEELVA----NL
DRPLNLCDMDFTDLGSDDEADVL-APAAVFNG---------IPPPPPPLKEN----GAPP
PPPLSKG----------------PPP---------VPNPPVFGVTL--------------
-PRMSKQAETKI--------------PIKKNKKTVKLFWKE--V-----------REDPV
CSSKLK-----TGFIWDEL-----KPVCVDTQKLEHL---FESRAKDL-------IT--K
KQQEMNKNKEIIVLDPKRSNAINIGM--TKLP-PPRSIKTAILKMDAT-IMNREGIEKLL
TMLPTEEER-SKIQEAQAANPDL----PLGSAEQFLLTLASISELPARLKLWAFKLDFEN
SEREIAEPLMDLKQGIEVLRVNKTFRGILSTLLSIGNFLNG-----NEVKGFQIDYLAKV
PEVKDTVHK-HSLLHHLCHIVMEKFPDATD-----LY-SEIGAITRASKIDFDELA----
---LNIQRLE---ADCKASWDHLKLIAKHDGSTMMKVKMSDFLADCAERIILVGIIHRRV
MNR-------------------------FHKFLLW-------------------------
-----------LGIPL--HQLSDTKPNEFCRI---VSEFALEY---RTTRERVLQQLEKK
ANHRERNKTRGKMITDIGKFRTK---------------------EDRADAELRQLLGSDI
SDVE-------SMQGTLPWRRTRR----DSNRSFLGQANG-NLTDGD-----DEILE---
-----------SLVK--TATKGPS-RT-APRERKRTRHADRK------------------
------SLRRTLKNGLSEE------------EKKHLSAYIKGY-----------------
------
>gi|126290361|ref|XP_001372702.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
-------------------MSGKEGV-QKKWAALKEKLGPQDGDPTEANLENAEPELCIR
LLQMPSVVNY--------------SGLRKRLESSDDG-------------WLVQFLEQS-
------------------------------------------------------------
----------GLDLLLEAL--ARLSGRGVARIADALLQLTCISCVRAVMNSQQGIE----
-----YILSNQGYV-CKLS-EALDTSNVMVKK-----------QVFELLAALSIYSP---
------EGHKQTLDA----------------LDHYKVVKSQQYRFSV--IMNELSSTDN-
----------V---------PYIITLLSVINAIILGTEE--------------------L
RARTQLRNEFIGLQLLDILTKLRDIEDLDLLIQCETFEEA--------------------
---------------KSEDDEELLRIFDGIDMSSHQEVFSTLFNKVSCSPISV-------
----------QLLSVLQGLLH-LEPAQHSSLLLWEALEILVNRAVL--------------
-----------------------LASDVQESSIEEIVERLLSMKMRPQQSPKICNLVKTA
HKCIQTNLD----------------------RAGSSPKGSQKEKGARPLSDNGTLETVTA
FQMQT-----------------------------ASAT-----PELHTS----TPDPAV-
-----VPHVGKTSIPPPPPPPPLPSFLWAPPPATPMSSKTSVPSPP--------------
-------------PPPP--PPPLPGMTRTPST-------TPPCPP---LPGVGG----IP
PPP------PLPGLGGIPPPPPL-PGLGGIPPP-PPLPGLGSIPPPPPLPGL----GGIP
PPPPLPGLGGIPPPPPLTGMACVPPPPPPLYGEI--PPPPMNGTEEIIVAHVDH------
-GLGLVRVPNHRK-------------VNPPTLRMKKLNWQK--L-----------PSNVV
RDS---------HSMWASVSSLSNETMEPDYSSIEQR---FCFPITKPK------EK--E
AAPVKKEPKEITFLDAKKSLNLNIFL--KQFKCPNEEITDMIRRGDRT-RFDVEVLKQLL
KLLPEKHEM-ENLKSFQEEKA------KLASADQFYLLLLNVPSYQLRIECMLLCEETVI
ILDMIKPKAEVIRKACESLLTSQRLPIFCQLILKIGNFLNYGSHT-GDADGFKISTLLKL
TETKANQSR-VTLLHHILEEVEKNYPDLLQ-----LP-NDLEHISRAAGINIDVIHSEAS
TNLKQLLEMERKVSSGIPEVQEQYVKPLQDSISASRELEEEFKVIERQKIKLADYLCEDA
HKLSLEDT--------------------FSTMKTFRELFIRALKENKDWKEQAVKAEKRK
KQLEAEEAKRPRGEDGKIIRKGAVKQEEVCVIDALLADIRKGFQLRKTAKGKADSENGLK
AAPPETSKEKEAVIKDTGSSTNSGQDFDLAAAIG----------ETSDQDNPDGPGSTGG
---------IPKGHSEVSGSGCRNPEGNKVSTPMAGFPDDPHMIQFDDSKSLKPIKFSSG
SFSGGTNMG--SEVDATRTGDQASEHQ-ADRTSEGPKNGFQRSEEAESTPPEGEEEEEEE
DTAPDSVLDTSLDRSFSEEAITDSSGSGTLPRSQERTKKGSGKRRKKRHSRSHEGLRPKP
KAK---
>gi|119916098|ref|XP_001253457.	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------VTPWSNIM--EILEEKDGVDT---ELLVYAMTLVNKTLSGLPDQD----
-----TFYDVVDCL-EELGIAAVSQRHLTKKG-----------ADLDLVEQLNIYEVALR
LEDGDETAEPPPSGCRDRRRASVCSGGT---GSEPRGLDRRRSRRHS--VQNIKSPLSPP
SSPCSLSAPDF---KPSQVRDLREKYSSFGNNSHHSSRPSPGSSVPTTPTS----SVSPP
QEARPERSSVSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFSREYLDKRE
EQRQ-----------AREERYKYLEQLAAEAHEKELRS--RSASRGRADLSLDLTSPAAP
ASPAPLGRSPSSLDSQEVPTVSSSSPGTPQHPQASAGEPGPEPEAD----------VEAE
VGQVADEAGQELAPASAGAESEVERALEPEHEERASLSEKERQNEAVN-ERDNCSASSVS
SSSSTLEREDREDKLSRDKGT--GLW-----SAGVQDAGVNEQCGDILTSKRFMLDMLYA
HNRKP--------------------------------------ADDEEK----GEGEAA-
-----RTAQGAEAVASLASRISTLQASSLAQDESVKRVDVGCLDNR-----GSVKAFAEK
FNSGDLGRGSVS-PDAE--PNDKVAEKTSAQPK------TESDYI---WDQLMA----N-
PRELRIQDMDFTDLGEEDDIDVL-DVD--LGHPEAP-----GPPPPPPPTFL----GLPP
PPPPPLL--DSV----------PPPP---VPGNLLAP-PPVFNAPQ--------------
-GLGWPQIPRGQ-P------------AFTKKKKTIRLFWNE--V-----------RPFEW
PCKNNGRC---REFLWSKL-----EPIKVDTSKLEHL---FESKSKELS------VS--K
KTAADGKKQEIIVLDSKRSNAINIGL--TVLP-PPRTIKIAILNFDEY-ALNKEGIEKIL
TMIPTEEEK-QKIQEAQLANPEV----PLGSAEQFLLTLSSISELSARLHLWAFKMDYET
TEKEVAEPLMDLKEGIDQLENNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKV
PEVKDTVHK-QSLLHHVCTMVVENFPDSSD-----LY-SEIGAVTRSAKVDFDQLQ----
---DNLCQME---RRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRI
INR-------------------------FHSFLLF-------------------------
-----------MGHPP--YAIREVNINKFCRI---ISEFALEY---RTTRERVLQQKQKR
ANHRERNKTRGKMITDSGKFSG-GSPAPLSQPQGLSYAE-----DAAEHENMKAVLKTSS
PAVEDA---TPALGVRTRSRASRG----SASSWTMGMDDSPNVT--DDAA--DEIMD---
-----------RIVK--SATQVPSQRV-VPRERKRSR-ANRK------------------
------SLRRTLKSGLTPE------------EARALGLVGTSELQL--------------
------
>gi|149637668|ref|XP_001506481.	Ornithorhynchus anatinus
---------------------------------------------------------MGR
VALGSGALDDCTLQLSHNG-----TYLDLESTLAEQRDDLEGFQEDAGRSKKQSIILRTQ
LSVRVH--------SCIEKLYNSSGR-ELRRALFSLKQIFQDDKDLVHEFVVAEGLTCLI
KVGAEADQNY---QNYILRAL---GQIMLYVDGMNGV-----INHNETIQWLYTLIGSKF
RLVVKTALKLLLVFVEYSESNAPLLTQAVASVDAKR------------------------
----------GAKPWSNVM--EILEEKDGVDT---ELLVYAMTLVNKTLSGLLDQD----
-----AFYDVVDCL-EELGIEAISQRHLTKKG-----------TDLDLVEQFNLYEATLR
HEDGDEGAEPPPSGRKDRRRASLG-------SNERRGLERRRSRRHS--VQNVKSPASAP
ASPCAPPTPNF---KPQCMKTLRHKYSNYGNSSFATSRTYCGPSTSATPSSRYGTSLSSP
EETKPDRSAVGGLLTSSYRQHQESLSAERERRRQEREERLQRIEREERNKFNQDYLDKRE
EQRQ-----------AREERYKYLEKLAAEEYEKEVKT--RSPCRDRSEPSLNVSSPAAS
ASVGPEGSGPPTADPQEGRRTSSTPQGTPPTLEARPSCPEPAREAE------------AE
AEQGASKAPREVESPAGGPDSEVEPGEEGEPEENAILGEKERQNGKND--GKNSRAFALS
RKAADVSRLFSRHVLIRPVYAILGSW-----SQPSQDAGVNAQCGNILNNRRFMLDMLYA
HNKKA--------------------------------------KDEEEKEPEKTTEEKE-
-----AEEEGEEPVATLAGRISILQASAQTKEDAVKKPEARGLDNQ-----GGVKAFAEK
FNSGELAKGSSS-PESE--LDEKVSESSQSQPK------KESDYI---WDQLMA----N-
PRELRIRDMDFTDLGAEDDLDVL-DME--VGPGDSP-----VPPPPPPPSFL----CFPP
PPPPPPF--GCP----------PPPP---AHPNLLAP-SALLSSPQ--------------
-GSGSPQVPR----------------AFVKKKKTIRLFWNE--V-----------RPCQW
QCKNDKRC---KEFLWSKL-----EPIKVDTSKLEHL---FESKSKELP------VT--K
KTAADGKRQEIIVLDSKRSNAINIGL--TVLP-PPRTIKIAILNFDEY-ALNKEGIEKIL
TMIPTEEEK-QKIQEAQLANPDT----PLGSAEQFLFTLSSISELTARLQLWAFKLDYEL
IEKEVAEPLLDLKEGMDQLEKNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKV
PEVKDTVHK-QSLLHHVCTMVVEKFPDSTD-----LY-SEIGAITRSAKVDFEQLQ----
---DNLCQME---RRCKASWDHLKAIAKHEMKPVLKQKMSEFLKDCAERIIILKIVHRRI
INR-------------------------FHSFLLF-------------------------
-----------MGHPP--YAIREVNINKFCKI---ISEFALEY---RTTRERILQQKQKR
ANHRERNKTRGKMITDTAKFSS-TSAVAPSQPQGLEYAE-----DAVEHENMKAVLKTSS
SLGGES---ASVLGVRTRSRASRG----RVGSWNAGMDDSPGAT--DDAA--DEIMD---
-----------LIVK--SATQVPSQRT-MPRERKRSR-ANRK------------------
------SLRRTLKSGLTPE------------EAKALGLVSTSEMQV--------------
------
>gi|121945683|sp|Q2V2M9|FHOD3_H	Homo sapiens
------------MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHR
LLQAPHKLDDCTLQLSHNG-----AYLGLEATLAEQRDELEGFQDDAGRGKKHSIILRTQ
LSVRVH--------ACIEKLYNSSGR-DLRRALFSLKQIFQDDKDLVHEFVVAEGLTCLI
KVGAEADQNY---QNYILRAL---GQIMLYVDGMNGV-----INRNETIQWLYTLIGSKF
RLVVKTALKLLLVFVEYSESNAPLLIQAVTAVDTKR------------------------
----------GVKPWSNIM--EILEEKDGVDT---ELLVYAMTLVNKTLSGLPDQD----
-----TFYDVVDCL-EELGIAAVSQRHLNKKG-----------TDLDLVEQLNIYEVALR
HEDGDETTEPPPSGCRDRRRASVCSSG----GGEHRGLDRRRSRRHS--VQSIKSTLSAP
TSPCSQSAPSF---KPNQVRDLREKYSNFGNNSYHSSRPSSGSSVPTTPTS----SVSPP
QEARWERSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREE-------------
---------------RNKFRYKYLEQLAAEEHEKELRS--RSVSRGRADLSLDLTSPAAP
ACLAPLSHSPSSSDSQEALTVSASSPGTPHHPQASAGDPEPESEAE--------PEAEAG
AGQVADEAGQDIASAHEGAETEVEQALEQEPEERASLSEKERQNEGVN-ERDNCSASSVS
SSSSTLEREEKEDKLSRDRTT--GLW-----PAGVQDAGVNGQCGDILTNKRFMLDMLYA
HNRKS--------------------------------------PDDEEK----GDGEAG-
-----RTQQEAEAVASLATRISTLQANSQTQDESVRRVDVGCLDNR-----GSVKAFAEK
FNSGDLGRGSIS-PDAE--PNDKVPETAPVQPK------TESDYI---WDQLMA----N-
PRELRIQDMDFTDLGEEDDIDVL-DVD--LGHREAP-----GPPPPPPPTFL----GLPP
PPPPPLL--DSI----------PPPP---VPGNLLVPPPPVFNAPQ--------------
-GLGWSQVPRGQ-P------------TFTKKKKTIRLFWNE--V-----------RPFDW
PCKNNRRC---REFLWSKL-----EPIKVDTSRLEHL---FESKSKELS------VS--K
KTAADGKRQEIIVLDSKRSNAINIGL--TVLP-PPRTIKIAILNFDEY-ALNKEGIEKIL
TMIPTDEEK-QKIQEAQLANPEI----PLGSAEQFLLTLSSISELSARLHLWAFKMDYET
TEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKV
PEVKDTVHK-QSLLHHVCTMVVENFPDSSD-----LY-SEIGAITRSAKVDFDQLQ----
---DNLCQME---RRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRI
INR-------------------------FHSFLLF-------------------------
-----------MGHPP--YAIREVNINKFCRI---ISEFALEY---RTTRERVLQQKQKR
ANHRERNKTRGKMITDSGKFSG-SSPAPPSQPQGLSYAE-----DAAEHENMKAVLKTSS
PSVEDA---TPALGVRTRSRASRG----STSSWTMGTDDSPNVT--DDAA--DEIMD---
-----------RIVK--SATQVPSQRV-VPRERKRSR-ANRK------------------
------SLRRTLKSGLTPE------------EARALGLVGTSELQL--------------
------
>gi|125821130|ref|XP_694795.2|	Danio rerio
-----------------------------MQPVQMLEAPGFRQKLLEALSLGRRQKYCLP
HMQREDPQPHTHTLAHVPGARR--PSLPHSFCREEESESELLYLSFVTACSSA-PLSSSS
LS------------SASSSSSSSDSE-SSSWSPRRRHTHSSHGLKPPPLIMGNQDAKLKR
DAGAAADDNGAYEGAKKGKKSHGKGEGGKKKNKSDRSSVFPHIRKRKNQNKLKGVLSGSK
EDALDSQHDELDSAPSLC-NKTPDLSGDELDVESER------------------------
----------PRLVADSRQ--ATLDANEDEEK--IRMLEAIPKAENGCVSALEDKE----
-----TTISRNEALCAPVAVETITKDPPPPPPPPAPPAVTMTPSTSNLTASFESAVEAVE
EQQPEDSTPDAPPSADTISEEDHLG------SAGSSGWSQQESPLATRLLKSSVKPYPP-
---------------------ISTSYIKTTTRQLSSPSCSPGPSPS--------------
HSPLFTRREHAVTLARAERRRVKRQRSYSITGPISRSADWTEEIRTLPP-----------
---------------KTTGSADYLEYGGSEGTLRSDRTL-SASQRASATRASTCSFQEVF
TGRTLLERFFQQQDSSEPEEAEKLCSKILAMGLLLPFSDCFRETYS----------SSGH
LAPQFDQDQLYTWAAVSQPPPSLERLEGHLPGHLKGLWIPTQPGEEEQPLAKYTEDVWIC
FSSPHLCLCVQEDSVLK--------------TVRLKQEHICVIEQLEQTIEDLRSKIAEL
EKQQP------------------------------------LPEREVETQDQECGGEEGL
HPDVCHVDLQTENTSLLPLEAKSVQTSPVDESYRFKVPPVEVRRDSLLASQTESQAASQS
FVCICQQQTSTSAPPP---PPPLPGVCAPPPPPPLPGVCVPTPPP---LPGVCP----PP
PPP------PLPGVCAIPPPPPL--PGASLPPPPPPLPCLSVPPPPPPLPGM----GAPP
PPPPLPGLSAPPPPPPLPGMGVPPPPPPPLTHTGPAPPPPPPPIPPSMAPGACAPPLAFG
FGSLPPPLPLGLFALGAVQEKPPRKCIVEPPRPMKPLYWTR--I-----------QLHTK
KDS--------NAVVWDTI-----EEPSVDFDEFVDLFSKTAVKEKKKP------LS--D
TISRSKTKQVVKLLNTKRSQAVGILM--SSLHLDMKDIQHAILNLDNT-VVDLETLQALY
ENRAQQDEL-DKIEKHIKSSKDKEGTKPLDKPEQFLHQLSQIPNFSGRVFCILFQSTFSE
CITSVQRKLQILQKVCKTLQSGSGVLQVLGLVLAFGNFMNGGNRTRGQADGFTLDILPKL
KDVKSSDNS-KSLLAYIVSYYLRHFDEDAGRETCVFPLPEPHDLFQASQMKFEDFT----
---KDLLRLRKDLRACTAEVEKVCSVSTEEHLQPFKEKMEAFVTEAKTELEGQEKQLSDT
HKL-------------------------FLDLCVF-------------------------
-----------FSVKAK-SGEKEVSPNTFFSV---WHEFCTDF---KDTWKKEN-----K
LILQERYAC---------------------------------------------------
----------------------------------------------------ECMCD---
------------------------------------------------------------
------------------------------------------------------------
------
>gi|115842008|ref|XP_792350.2|	Strongylocentrotus purpuratus
------------------------------------------------MTVTDSMTIINP
DSDDETDSDT-----------------DYEADIDDTDDNCIDM-----------TRRRSS
LKLR----------PDSDALFIEQLA-DLMCQPQPGNDIMA---------LLSQGDDSSK
DRSSTISSKF---LTYDITFRVGHTPHTIEIRQIFIN-----------------------
-----------DVYRLNREFKNIILKKNRHNTKHSR------------------------
----------GCLIWKRRR--NRDTDSESVAS----------TDTTETKKDEPTMS----
-----AYVPRSRRR-AEVVEEKTPEEKPADKP-----------AE-DIRDHFS-------
--SSQHQAQSPLREHQESIAARRN-------RREEADKDEKMEKASK--EKEEKASKQA-
-------KKDA---------DSRSANMILNQLRSGDVKAKPTENGD--------------
------------------ISRPDDETSSRHRWRRDRGDVKE-------------------
---------------KPDETKVVNGDISSVHKPKEAVE--TKAKDESREPVKD-------
-------------SKPADTKDEEKKPEEPKKRTFIDKKDEAPKEIV--------------
--------------------------------------ENEKAQTDPS-DRGNLLTVKTS
DQDEN------------GSS-----------DVKSRKISTTLQNVKKLEERKADLLVVKE
KE-----------------------------------------EEEEGK----KVQEDK-
-----EILNNSGAVQSMHKQLQAQQDKSEDQKEKEKVKAGPRGDVS-----GKISQAIEG
MKVSNVAPKASE-P-----VTPIEDEGKQEEEA---------------WEEVLK----LN
DRELRINKWDFTDLCRDDDKDVLKSIPLMMGMVPYMTLPDGAPPPPPPLPGL----GIPP
PPPIPGA-----P---------PPPPPPAMKGPGAPPPPPIIDSNT--------------
-F------------------------PKSKKKKTVRLFWKE--T-----------QPETM
TLGRNGM----KSTIWTQL-----DDVNIDSKKLEHL---FEYRGKDL-------IT--K
KAMEANKKNFITVLDPKKSNAINIGL--TVLP-QPRSIKQAILNMDSM-VMNKEGVEKLL
SMVPSEEEV-ARIQEAMLANPDV----PLGSAEQFLHMLSTISGLEARLNLWLFKMDYDN
MEEEVAEPMADLKKGIEDLRASKTFKKILSTLLAIGNFLNG-----GRAAGFNLEYLSKV
PEVKDTVHK-QSLLHHLAASVMEQFPESSD-----FF-SEVGTISRCAKVDFDQLT----
---INLTKLE---EQCKTSWNHLQVITQHEKTPGNKNKLHDFLQDCAKRIIVLKIVHRRV
SNR-------------------------FNGFLLY-------------------------
-----------LGMST--SAAREVKISHFCRI---ISEFALEY---RSTRERIIEQEKKK
ANHRKRNKTRGKMITENFSISK----------------------DSAEDAKLKELL-SSQ
QGTAPG---DETLQSRQRARPSMS------GRMNMSMTADEEVA--DEQT--DEMIQ---
-----------ILVN--TAKNTST-RS-APRERKRTRNTNRK------------------
------SLRRTLKSGLTDA------------ERQALGLLHAKPNEVHV------------
------
>gi|110749463|ref|XP_395654.3|	Apis mellifera
-----------------------------MANRKDKSSTGFLDTWFGRPKKSGRGGGVRS
GLGNNTIPRPHSGDDFNEIEQQ--RCIIERMDKENSNDKFEE------------MLANMN
LT------------EEKKEPLRQQSE-AKKREMLVLH---------------YKGSIQEN
KSKFDKPADY---IQYLAQPDLSVNKIYNCIESLRIA-----LTNNP-LSWVQEF-----
------------------------------------------------------------
----------GTKGLKQVL--ATLNECYRNDNRYERIQYECIRCLKAIMNNTVGIK----
-----EMLAHQEAL-TIVAR-SLEPTKPSVMS-----------EAVKLLGAVCLISS---
------DSHKKVLD-----------------AITMNGEFKGRERFLP--IVQGLMNKKN-
----------E---------NLRVECLQLINSIISSAEE--------------------L
DFRLHLRNEIMRVGLADILETLEKNESEDLARHLKIFNDH--------------------
---------------KEEDYEEFVQRFDHVRLELDDVN--DCFEVIKNMVMET-------
------SAEPYFLSILQHLL--FVRDDALVRPAYYKLIEECVSQIV--------------
------------------------------------------------------------
-------------------------------------LHRSGCDPDFSATKRFQIDVQPL
I------------------------------------------DTLVEK-----------
-----SRVEEERRLVEVLQKLEEAIASKQEAEAKLQHAENKIRELE------------QG
GIKSTNGNKI---------GSVLSGLAGIGNLP-------PPPPP---LPNASGSAIIAP
PPP---------------PPPPL-PGSSG------------LCPPPPPLPGL----GGPP
PPPPMPGTLAG-----------PKPPPMPQSG----PPPPMMIGI---------------
-NSTSQSLPLGLKPKK----------KWEVDAPLKRANWKA--I-----------MPHKL
T----------EKSFWIKV----QEDKLASPEILNGLSLKFASKPSGKKIDD---VV--D
KSAPSKKVKDLKVLDGKAAQNILILLNGTLKHMSYEEVKSCLLKCEGP-VISDNILQGLI
QYLPPPDQL-KKLHFYKDQYD------DLTEAEQFCITISTIKRLLPRLRSLSFMLRYEE
LVQDVKPDIVAGTAACEEVKDSKKFARILELILLLGNYMNSGSKN-GQAFGFEISFLTKL
TSTKDVDNK-QTLMHYLVDTIEQKFSECLS-----FT-EELAHVDRASRVSLENVQ----
---RTLRQMDSSIRNLEQDLSNAKI--PQSDEDMFLHVMGPFAKKARESYEVLQNMFKNM
DSL-------------------------YTEISEF-------------------------
-----------FSF-----DKQKYTIEEFFGD---IKTFKDDF---MQAQKEII--KMRE
TEEKQRRAREAREKAEAEKAARVARKIALV--------------DMNAHETQEGVMDSLM
EALQTG---SAFSRPDQRRKRQTR----AAGGTAVKLSPVKRR---------QVIVS---
-----------KKRKRNSIVRRVVKNR-KQRHLRSSDNQKARKLFSYLGS----------
------PISETERRAQLNR------------SRSRTGLVGTGLLGRELSTELISSA----
------
>gi|47225541|emb|CAG12024.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
-----------------EKLYNSTGR-ELRRALFSLKQIFQDDKDLVHEFVLAEGLTCLI
KVGAEADQNY---QNYILRAL---GQIMLYVDGMNGL-----ISHNETVQWLYTLAGSKF
RLVVKTALKLLLVFVEYTESNATLLIKAVDVVDGKRALWITMTWSNENLREPAISVSYLP
EILHMLFTAAGKKVWSNIM--EILDEKDGVDT---ELLVYAMTLINKTLAGLSDQD----
-----SYYDMVDGL-EEQGIEALGQRHLSRKG-----------TDLDLVEQFNIYEMTLR
HEDGDNDAQLPPNGRKDRRRASVGG------TSERRGLERRRSRRHS--LQSHRGHASAP
ASPCGPHPQGSGGSVPFSSPRIDDISERIRATDGRNQLTTTPTDHLTSP------AASTA
DSKQPDRSALGGLLSSS--RHQDTLAADRERRRQEREERLQRIEREERNRVSRNYVEKRE
EARQ-----------AREERYRAVERLAAGEFERERS---RVPTRGRTEITLC-------
---------------------LSSAPTSRSVSRCITPSPAVQQEST--------------
--------------------------------------------------------ATAA
YGSP-------------------GQW-----SQSIKDADVSEDCNKILNSKRFMLDMLYA
HKTTG--------------------------------------SQEDNE----GETAKET
YMFKKETEVGDTSVASLASRISTLEAHRQAREEHMKKMEVGHLDNQ-----GNVRAVAEK
FGDLVKGLTSPADAEPVKEGDRLPGSAGTTLPPK-----KESDYI---WDQLMA-----S
PRELRIKEMDFTDLREEDDVDFL-DMDTVIGSGDM------IPPPPPPPCST----ALPP
PPPLFGC---------------PPPP---PALGKMMPPPPPFMAPF--------------
-PPPSPKMSCEEAP------------LFQKKKKTIRLFWKE--V-----------HQVDW
PCKSHRLC---RESLWSKL-----EPIKLDTSKMEQL---FESKSKELP------VT--K
KATVDGKRQEIIVLDSKRSNAINIGL--TVLP-PPRTIKTAILNFDEY-ALNKEGIEKIL
TMIPTEEEK-QRIQEAQLVNPDV----PLGSAEQFLLTLSSITELSARLQLWAFKMDYEL
TEKEVAEPLQDLKEGMDQLEKNKTLRYILTTLLAIGNFLNS-----TEAKGFELSYLEKV
PEVKDTVHK-QSLLHHVCAIVVEKFPDSTD-----LY-SEIGAITRLTKVDFDQLQ----
---DNLLQME---RRCKASWDHLKVIAKHEMKPALKQKMSDFLKDCAERIIILKIVHRRI
INRFVPPVLLRFSFGLSCLSDISLPVPRFHAFLLF-------------------------
-----------LGHPV--YAAREVSVHRFSKI---LSEFALEY---RTTRERVLQQKLKR
ANHRERNKTRGKMITDSGKFGGASSEVQENQPQGIQSAE-----EAAEHENMKAVLKSGL
QAGDTG---RPPCRASARALAPATPEVLRVAPWCPASEDLLNGT--DDTA--DEIME---
-----------RIVR--SATQGPSQRA-QPRERRRSR-VNRKSRKSDWQVRSERISAVTC
VISFGFSVRRTLKNGLTPE------------EANALGLSSGSEMQV--------------
------
>gi|73961729|ref|XP_537280.2|	Canis familiaris
------------MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHR
LLRAPHKLDDCTLQLSHNG-----AYLDLEATLAEQRDELEGFQDDAGRGKKHSIILRTQ
LSVRVH--------ACIEKLYNSSGR-DLRRALFSLKQIFQDDKDLVHEFVMAEGLTCLI
KVGAEADQNY---QNYILRVL---FNLYCYWESLPFL-----LYRNSRLEWLYVILGSPF
RLVVKTALKLLLVFVEYSESNAPLLIQAVSAVDTKR------------------------
----------GVKPWSNIM--EILEEKDGVDT---ELLVYAMTLVNKTLSGLPDQD----
-----SFYDVVDCL-EELGIAAVSQRHLNKKG-----------TDLDLVEQLNIYEVALR
HEDGDETAEPPPSGRRDRRRASVCSGGSSSAAGEQRGLDRRRSRRHS--VQSIRSPLSAP
TSPCSQSAPGF---KPSQVGEHCEKYNSFGNTSYHSRPSGSAAPATPTS------SLSPQ
QEAKLERSSLSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFNREYLDKRE
EQRQ-----------AREERYKYLEQLAAEAHEKELRS--RSASRGRGDLSLDLTSPAAP
ASPTPLHRSPPSLDSQEALEGSSSSPGTPQHPQASAGDPEPGPEAE--------------
VGQGTDEASPEVAPAHVGAESEVERALEQEPEERASLSEKERQSEEVN-EKDNCSASSIS
SSSSTLEREEKEDKLSRDRGT--GLW-----SAGVQDASVNEQCGDILTNKRFMLDMLYA
HNRKP--------------------------------------TDDEEK----AEGESG-
-----RAEPGAEAVASLASRISTLQAHSLAQDESVRRVDVGCLDNR-----GSVRAFAER
FNSGDLGRGSVS-PDAE--PSDKAPEKASAPPK------TESDYI---WDQLMA----N-
PRELRIQDMDFTDLGEEDDVDVL-DVD--LGPREAP-----GPPPPPPPTFL----GLPP
PPPPPLL--DSVV---------PPPP---VPGNLLAP-PPVFNAPQ--------------
-GLGWPQVPRGQ-P------------AFTKKKKTIRLFWNE--V-----------RPFEW
PCKNNRRC---REFLWSKL-----EPIKVDTSRLEHL---FESKSKELS------VS--K
KTAADGKRQEVIVLDPKRSNAINIGL--TVLP-PPRTIKIAILNFDEY-ALNKEGIEKIL
TMIPTEEEK-QKIQEAQLANPDV----PLGSAEQFLLTLSSISELSARLHLWAFKMDYET
TEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKV
PEVKDTVHK-QSLLHHVCTMVVENFPDSSD-----LY-SEIGAVTRSAKVDFDQLQ----
---DNLCQME---RRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRI
INR-------------------------FHSFLLF-------------------------
-----------MGHPP--YAIREVNINKFCRI---ISEFALEY---RTTRERVLQQKQKR
ANHRERNKTRGKMITDSGKFSS-SSPAPLSQPQGLTYAE-----DATEHENMKAVLKTSS
PAVEDA---TPVLGVRTRSRASRG----SASSWTMGTDESPNVT--DDAA--DEIMD---
-----------RIVK--SATQVPSQRV-VPRERKRSR-ANRK------------------
------SLRRTLKSGLTPE------------EARALGLVGTTELQL--------------
------
>gi|24661140|ref|NP_729410.1|	Drosophila melanogaster
----MIVKMEPDELITFRVQYLVDSDPLSACTAFPIPVRAPTYAFATTMPLANQLGTILR
LLNAPQSIDDAAIQVYKDGDYG--AYLDLESSLAEQAEEIEGVNVSRKNS----LVVRTQ
LNVRVQ--------AIIEKLLSAQGS-DLRRALFSLKQVFQEDKDLVHAFVALGGLNCLV
RVGNCADQNY---QNYILRAL---GQVMLYVDGMNGV-----MKHEPTMQWLYSLIASNY
RSVVKTALKLLLVFVEYAESNCYVLVSAIHAVDASQ------------------------
----------GTLPWSNIM--RLLKDYDNADA---ELVIYATSLINKTLAGLNDQD----
-----SFYDESDLL-EQQGMETVIQRYMSKPG-----------TDLDLLDQLQLYEAVLK
FEDGESDGQRLPQNS--MRKTQRY-------RPGANTTERRKSRRHS--TDNSPASLTK-
--------------------VLPTTVLRMTPTQATVDEDSSGSTNS--------------
-------TEFSGGLFNEKKPRDGAGVTPGLRRRRERAERHKSFLKEQQE-----------
A--------------AANGIFAALEQREGLGQIVTAIP--ATIQTGDSPPQSL------Q
HEVPPCNNISGITNISNNNVSNLSCNDTPNNSLLVMSPSKQLLTGSHSISIINNSFDKAS
NNNQSEFLTKKNLFRERNSTVINGIMKNIQQTDSA----YKKYENEAN-RLNNYYSQSPK
HQIHQPIQPTPEVLLSPKKTLNASGF-----DFTPAPLSSTPVKCDVPPEPEPLSPVKKP
AAAPPPPPPPPPPPPPPPGWWHAPIYNSPQARTLTSTNPELLPHPVDPSDMESEDQQLL-
-----LQLKRDHTVKDLTQKLSNLPMSPTQDSAN----RALVGDMS-----GLISKAKEG
LAKSKSKGEISR-------SSSVDQDVKKSEPKK-----SENELH---WEELVR----NM
TRPLNLCDLDFTDLRDDDEKDVL-APRS-LGAG--------IPPPPPPLGGA----IAPP
PMMPPSL---------------APPP---MYGYGGSLTNSVNSLN---------------
-GSINGELVNGNN-------------TIKKNKKTVKLFWKE--V-----------REDMI
PQVV-------GKTIWDEL-----PDANVDTQKLEHL---FESRAKDL-------MT--K
KQQELNKSKEIIVLDHKRSNAINIAI--TKLP-PPRAIKTAILKMDAT-VVTREGIDKLL
NMLPTDEER-GKIQEAQLSNPEL----PLGSAEQFLLTLASISELEARLKLWAFRLDFDN
SEKEIAEPLMDLKQGIEILRQNRTFRSILSTLLSVGIFLNG-----APVKGFQIEYLAKV
PEVKDTVHK-HSLLHHLCHMVMESSSDTSD-----LY-SEIGPITRASKADFTDLA----
---HNLNQLE---AECKACWDRLKLIAKHDCPPPLKQKLVDFLADCAERIIILQIVHRRV
MNR-------------------------YRKFLLW-------------------------
-----------LGMPQ--HSVAESRPNEFCRT---LSEFALEY---RTTRERVQQQLEKK
ANHRERNKTRGKLIIDMAKFKTK---------------------DDVADDELKKLLDTSS
ADQADG---------TLTWRRRRA----EQLRSPITRQSEEQFTDGD-----DEILE---
-----------SLVK--TATKAPGTRT-TPRERKRTRHADRK------------------
------SLRRTLKNGLTEE------------EKQHVAALIQTY-----------------
------
>gi|149017093|gb|EDL76144.1|	Rattus norvegicus
------------MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHR
LLRAPHKLDDCTLQLSHNG-----AYLDLEATLAEQRDELEGFQDDTGRGKKNSIILRTQ
LSVRVH--------ACIEKLYNSTGR-DLRRALFSLKQIFQDDKDLVHEFVIAEGLTCLI
KVGAEADQNY---QNYILRAL---GQIMLYVDGMNGV-----INHSETIQWLYTLVGSKF
RLVVKTALKLLLVFVEYSESNAPLLIQAVSAVDTKR------------------------
----------GVKPWSNIM--EILEEKDGVDT---ELLVYAMTLVNKTLAGLPDQD----
-----TFYDVVDCL-EELGIAAVSQRHLNKKG-----------TDLDLLEQFNIYEVALR
HEDGDETAEPPPSGHRDRRRASMCSGGT---VGEQQGLDRRRSRRHS--IQNIKSPLSA-
---------------------PTSPCSQTVPAFKPSQVR---------------------
--DLCEKSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFNREYLDKRE
EQRQ-----------ARGERYKYLEHLAAEAHEKEQRS--RSASRGRADLSLDLSLPAAP
ASPSPSSPSPDSADSQEALTAPSTPP-TLQYPQVSGKDREPELEAE--------------
AGQGADEASRDIASAHREAGSQEEPALELEPEERASLSEKERQNEEVN-ERDNCSASSIS
SSSSTLEREEKEDKLSGDRPT--GLW-----SASLQDVGVNGQCGDILTSKRFMLDMLYA
HNRKS--------------------------------------TEDEEK----GDGEPG-
-----RSAQEVEAVASLATRISTLQANSQAPEESIKRVDIGCLDNR-----GSVKAFAEK
FNSGEVGRGSVS-PDAE--SQDKVPDTPPAQLK------TESDYI---WDQLMA----N-
PRELRIQDMDFTDLGEEDDIDVL-D-----------------------------------
------------------------------------------------------------
-GLGWSQVPKGQ-P------------AFTKKKKTIRLFWNE--V-----------RPFEW
PSKNNRRC---REFLWSKL-----EPIKVDTSRLEHL---FESKSKELS------VT--K
KTAADGKRQEIIVLDSKRSNAINIGL--TVLP-PPRTIKIAILNFDEY-ALNKEGIEKIL
TMIPTEEEK-QKIQEAQLANPEV----PLGSAEQFLLTLSSISELSARLHLWAFKMDYET
TEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKV
PEVKDTVHK-QSLLHHVCTMVVENFPDSSD-----LY-SEIGAITRSAKVDFDQLQ----
---DNLCQME---RRCKASWDHLKAIAKHEMKPVLKQRMSELLKDCAERIIILKIVHRRI
INR-------------------------FHSFLLF-------------------------
-----------MGHPP--YAIREVNINKFCRI---ISEFALEY---RTTRERVLQQKQKR
ANHRERNKTRGKMITDSGKFSG-SSPAAPSQPQGLSYAE-----DAAEHENMKAVLKTSS
PALEDA---TPMLGVRTRSRASRG----STSSWTMGTEESPSVP--DDAA--DEIMD---
-----------RIVK--SATQVPSQRV-VPRERKRSR-ANRK------------------
------SLRRTLKSGLTPE------------EARALGLVGTSELQL--------------
------
>gi|37360647|dbj|BAC98303.1|	Mus musculus
------------MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHR
LLRAPHKLDDCTLQLSHNG-----AYLDLEATLAEQRDELEGFQDDTGRGKKNSIILRTQ
LSVRVH--------ACIEKLYNSSGR-DLRRALFSLKQIFQDDKDLVHEFVIAEGLTCLI
KVGAEADQNY---QNYILRAL---GQIMLYVDGMNGV-----INHSETIQWLYTLVGSKF
RLVVKTALKLLLVFVEYSESNAPLLIQAVSAVDTKR------------------------
----------GVKPWSNIM--EILEEKDGVDT---ELLVYAMTLVNKTLAGLPDQD----
-----TFYDVVDCL-EELGIAAVSQRHLNKKG-----------TDLDLLEQFNIYEVALR
HEDGDETAEPPPSGHRDRRRASMCSGGT---VGEQQGLDRRRSRRHS--IQNIKSPLSAP
TSPCSPSVPAF---KPSQVRDLCEKYSNFSSNSFQSSRPSPGPSGSPS-------YASSF
SSPQDTRSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFNREYLDKRE
EQRQ-----------ARGERYKYLEQLAAETQEKEPRS--QSVSRGRADLSLDLSLPAAP
APPSPSSQSPS--ADSQEALPVPSSPPTLQCPQVSGKDHEPELEAE--------------
AGQGADEASQDIASAHRGAESQEEPVLELEPEERASLSEKERQNEEVN-ERDNCSASSIS
SSSSTLEREEKEDKLSEDRAT--GLW-----STSLQDVGVNGQCGDILTSKRFMLDMLYA
HNRKS--------------------------------------TEDEEK----DDGEPG-
-----RSAQEVEAVASLATRISTLQANSQAPEESIKRVDIGCLDNR-----GSVKAFAEK
FNSGEVGRGAIS-------PDVESQDKVPDTPP--AQLKTESDYI---WDQLMA----N-
PRELRIQDMDFTDLGEEDDIDVL-DVD--LGHREAP-----GPPPPPPPTFL----GLPP
PPPPPLL--DSV----------PPPP---VPGNLLA--SPVFNTPQ--------------
-GLGWSQVPRGQ-P------------AFTKKKKTIRLFWNE--V-----------RPFEW
PSKNNRRC---REFLWSKL-----EPIKVDTSRLEHL---FESKSKELS------VT--K
KTAADGKRQEIIVLDSKRSNAINIGL--TVLP-PPRTIKIAILNFDEY-ALNKEGIEKIL
TMIPTEEEK-QKIQEAQLANPEV----PLGSAEQFLLTLSSISELSARLHLWAFKMDYET
TEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKV
PEVKDTVHK-QSLLHHVCTMVVENFPDSSD-----LY-SEIGAITRSAKVDFDQLQ----
---DNLCQME---RRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRI
INR-------------------------FHSFLLF-------------------------
-----------MGHPP--YAIREVNINKFCRI---ISEFALEY---RTTRERVLQQKQKR
ANHRERNKTRGKMITDSGKFSG-SSPAAPSQPQGLSYAE-----DAAEHENMKAVLKTSS
PALEDA---TPVLGVRTRSRASRG----STSSWTMGTEESPSVT--DDAA--DEIMD---
-----------RIVK--SATQVPSQRV-VPRERKRSR-ANRK------------------
------SLRRTLKSGLTPE------------EARALGLVGTSELQL--------------
------
>gi|114663095|ref|XP_511029.2|	Pan troglodytes
MAGGEDRGDGEPISVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGAQIPAVHR
LLGAPLKLEDCALQVSPSG-----YYLDPELSLEEQREMLEGFYEEISKGRKPTLILRTQ
LSVRVN--------AILEKLYSSSGP-ELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLI
RVGAAADHNY---QSYILRAL---GQLMLFVDGMLGV-----VAHSDTIQWLYTLCASLS
RLVVKTALKLLLVFVEYSENNAPLFIRAVNSVASTT------------------------
----------GAPPWANLV--SILEEKNGADP---ELLVYTVTLINKTLAALPDQD----
-----SFYDVTDAL-EQQGMEALVQRHLGTAG-----------TDVDLRTQLVLYENALK
LEDGDIEEAPGAGGRRE--------------RRKPSSEEGKRSRRSL--EGGGCPARAP-
------------------EPGPTGPASPVGPTSSTGPALLTGPASSP------------V
GPPSSLQASVNLFPTISVAPSADTSSERSIYKAR--------------------------
----------------------FLENVAAAETEKQ-----VALAQGRAETLAG-------
----------------------AMPNEAGGHPDARQLWDSPETAPA--------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------ARTPQS-
---------------PAPCVLLRAQRSLAPEP----------------------------
-------------------KEPLIPASPKAEPI---------------WELPTR------
APKLSIGDLDFSDLGEDEDQDMLNVESVEAGKD--------IPAPSPPLPLL---SGVPP
PPPLP-----------------PPPP---IKGPFPPPPPLPLAAPL--------------
----PHSVPDSS--------------ALPTKRKTVKLFWRE--L-----------KLAGG
HGVSASRFGPC-ATLWASL-----EPVSVDTARLEHL---FESRAKEV-------LP--S
KKAGEGRRTMTTVLDPKRSNAINIGL--TTLP-PVHVIKAALLNFDEF-AVSKDGIEKLL
TMMPTEEER-QKIEEAQLANPDI----PLGPAENFLMTLASIGGLAARLQLWAFKLDYDS
MEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNG-----SQSSGFELSYLEKV
SEVKDTVRR-QSLLHHLCSLVLQTRPESSD-----LY-SEIPALTRCAKVDFEQLT----
---ENLGQLE---RRSRAAEESLRSLAKHELAPALRARLTHFLAQCARRVAMLRIVHRRV
CNR-------------------------FHAFLLY-------------------------
-----------LGYTP--QAAREVRITQFCHT---LREFALEY---RTCRERVLQQQQKR
ATYRERNKTRGRMITETEKFSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTSRP
EDTTHN---RRSRGMVQSSSPIMP----TVGPSTASPEEPPGSSLPSDTS--DEIMD---
-----------LLVQ--SVTKSSPRAL-AARERKRSR-GNRK------------------
------SLRRTLKSGLGDD------------LVQALGLSKGPGLEV--------------
------
>gi|118086645|ref|XP_419037.2|	Gallus gallus
------------------------------------------------MLMRLLVEALVS
YLETDTLLDDCTLQLSHNG-----TYLDLESTLAEQRDELEGFQEDAGRGKKHSIILRTQ
LSVRVH--------ACIEKLYNSNGR-ELRRALFSLKQIFQDDKDLVHEFVIAEGLTCLI
KVGAEADQNY---QNYILRAL---GQIMLYVDGMNGV-----INHNETIQWLYTLIGSKF
RLVVKTALKLLLVFVEYTESNAPLLIQAVSTVDEKR------------------------
----------GAKPWSNIM--EILEEKDGVDT---ELLVYAMTLVNKTLSGLPDQD----
-----SFYDVVDCL-EELGIEAISQRHLNKKG-----------TDLDLVEQFNIYEMTLR
HEDGDETADPPPSGRKDRRRASLG-------GSERRGLERRRSRRHS--VQNVKSTLSAP
ASPCSQSNPSFMLGHGQRVDDLSERYNSYGSNSYSSPRPYSGLSAPTTPTSRYGTTLSPP
QESKSDRPALGGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFNRDYLDKRE
ELRQ-----------AREERYKYLERLAAEEYEKELKS--RSVSRGRSELSLNLRSPSAP
SSPVPKCVSPASIESQEELKTPSTPCGTPQHSEVSASEPEPETETE-----PEAEQETEA
EPEQGTETPKEIEATEVGPESEVEQGPEREPEESAILSEKERQNEEVN-EKDNCSASSIS
SASSTLEREEREDKLTSDNET--GPW-----SQTIQDAGVNEQCSKILNNKRFMLDMLYA
HNKKP--------------------------------------KDEEEKELE-AKEEKK-
-----ETEESEESLTSLASRISILQATKQAKDESVKKMEIGNLDNQ-----GSVKAFAEK
FNSGELAKGTAL-PEDE--ISEQVPEKTPAQPK------KESDYI---WDQLMA----N-
PRELKIKDMDFTDLGEEDDVDVL-DMD--MGPGDSL-----VPPPPPPPSFL----GLPP
PPPPPLF--GCP----------PPPP---PSANLLAP-PPLFSTPQ--------------
-GLGSPQVSRGQ-P------------AFIKKKKTIRLFWNE--V-----------RPFEW
QCKNNKRC---REFLWSKL-----EPIKVDTSKLEHL---FESKSKELP------VT--K
KTAADGKRQEIIVLDSKRSNAINIGL--TVLP-PPRTIKTAILNFDEY-ALNKEGIEKIL
TMIPTEEEK-QKIQEAQLANPDV----PLGSAEQFLLTLSSISELSARLQLWAFKMDYEI
VEKEVAEPLLDLKEGMDQLEHNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKV
PEVKDTVHK-QSLLHHVCTMVVEKFPDSTD-----LY-SEIGAITRSAKVDFEQLQ----
---ENLCQME---RRCKASWDHLKAIAKHEMKPTLKQKMSEFLKDCAERIIILKIVHRRI
INR-------------------------FHSFLLF-------------------------
-----------MGHPP--YAIREVNINKFCKI---ISEFALEY---RTTRERVLQQKQKR
ANHRERNKTRGKMITDSGKFSS-TSPSSPVQPQGLQYAE-----DAAEHENMKAVLKTSS
VSGES----TTTLGVRTRSRVSRG----RIGSWNAGNDDSPNAT--DDAA--DEIMD---
-----------RIVK--SATQVPSQRA-VPRERKRSR-ANRK------------------
------SLRRTLKSGLTPE------------EAKALGLISTSEMQV--------------
------
>gi|156552774|ref|XP_001602508.	Nasonia vitripennis
------------------------------------------MGNLQSEALGRRSKQRCR
SKDVSAASSASIVE----------ELLDSAPVSSVKSISF--------------------
--------------SCKPRVSCSGHG-PKPQTP---QHNLTKRPAPQPPRVAPQRRQTDE
PTGEAQSAET---GERDGQVA---RTVMPATAAEDVE-----------------------
-----------LQLKASKEAMSPLLL----------------------------------
----------VTDSWRRAN--RDLMPPGAASP----------------PSKESSSD----
-----SVFTDPGAA-SDQASLGESQDKLG---------------------------SVFR
TDDSHSDSHSAVSQIHLRTRASRAVAHQ---AGLLQTPKEKTSRRHT--TGDAAWASEG-
--------------------KLLRRVASFSNERNVVTKPQK------------------L
DLKLYERFE---------GQYLVNWATSGLSKHLKSQMSDID------------------
---------------LKAIGTAFCSHLVSAGILRTHPDNDEAAPQLNDSFKMD-------
---------HMYYWTPKDISAILVAEATKKPKNLSEKIEDLVDENT--------------
------------------------RLRKDLSELREVVKQSRIQTESKAVQTDSTSDLPVG
KA-----------------------------ADASSPMPKNREKEDRTSEKSSDSSGRFT
ASALD---------------------------------ISPILSEKTRSFIASEDLSGDV
SKAVKRPFKLESSLSSVIADRSAELPNAIENKYNMTNIKNDNNDNE-FKSNSEIIASLTP
MTEIVEDKPASL-SPPS--PPSRPEMLASLPPP-------PPPPP---MPGIMQ----PP
PPP------PMPGMMSGPPPPPP-PMPEMMSGP--------PPPPPPPMPGM--MSGPPP
PPPPIPGMMTGPP---------SPPPPPLVATVVGPPPPLPPGGPA--------------
-ALPLPPVGGWNPPSRAMIRKP----PVNPETPMKPLYWTR--IIVPAVQSEATGSISSS
PDSPV------KGSLWLEI----EEEPNVNFKEFAELFSRQANERKPA-------MK--A
STSRSLKVEPAKILDSKRSKMVGILE--KSLHVDFVEVENAVYTLDTS-TVSLEALQQIY
EVRPTSKEL-EDISAHEKERPDQ----PLDSPELFLKKLSNIQFFTERMACLMFQTEFAD
AMSSVSSKLTNLRSVCEFMLRSSSLKRVMALILTLGNYMNGGNRMRGQADGFGLEILGKL
KDVKSKVTG-VTLLHYVVKTKLSQEGAINFKEPLPLPVPEPADIQAAATVNFEDVA----
---KELEILGKRVEDCVSKCKVVEE-GSPENAGPFKLKMDAFLTRAHKELTNEAYAFQDA
RTK-------------------------FKAVMQF-------------------------
-----------YQYIPKGSTLDTAEPKDFFIL---WVSFCQDF---KDIWQREQQILKKI
EDIREKYKAQRNIETTKKK--EGGLKARLQKLKD----------LVSDATKGDWILDSGA
LTHMCY---DRGQLTNMTKSTITNVTAANKNKVPVRCEGLMKLRYNGSTGARKVLLQ---
---------RVLYVPDLTSNLISVSAI-AQRGGKVTFFGNRCQVYNHRGDLVLEGKLNAN
NIY---IIKLEPNVSQAQE------------SSQPQNSIPQTTEALLLQAMCH-------
------
>gi|109121987|ref|XP_001106633.	Macaca mulatta
------------MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLVGVHR
LLRAPHKLDDCTLQLSHNG-----AYLDLEATLAEQRDELEGFQDDAGRGKKHSIILRTQ
LSVRVH--------ACIEKLYNSSGR-DLRRALFSLKQIFQDDKDLVHEFVVAEGLTCLI
KVGAEADQNY---QNYILRAL---GQIMLYVDGMNGV-----INHNETIQWLYTLIGSKF
RLVVKTALKLLLVFVEYSESNAPLLIQAVTAVDTKR------------------------
----------GVKPWSNIM--EILEEKDGVDT---ELLVYAMTLVNKTLSGLPDQD----
-----TFYDVVDCL-EELGIAAVSQRHLNKKG-----------TDLDLVEQLNIYEVALR
HEDGDETAEPPPSGCRDRRRASVCSSG----GGEHRGLDRRRSRRHS--VQSIKSTLSAP
TSPCSQSAPSF---KPSQVRDLREKYSNFGNNSHHSSRPSSGSSVPTTPTS----SISPP
QEARLERSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREE-------------
---------------RNKFRYKYLEQLAAEEHEKELRS--RSVSRGRADLSLDLTSPAAP
ACPAPLSHSPSSLDSQEALTVSPSSPGTPHHPQASAGDPEPESEAE--------PEPEAG
AGQVADEAGQDIASAHEGAETEVEQALEQEPEERASLSEKERQNEGVN-ERDNCSASSVS
SSSSTLEREEKEDKLSGDRTT--GLW-----PAGVQDAGVNGQCGDILTNKRFMLDMLYA
HNRKT--------------------------------------PGDEEK----GDGEAG-
-----RTQQEAEAVASLATRISTLQANSQTQDESVRRVDVGCLDNR-----GSVKAFAEK
FNSGDLGRGSVS-PDAE--PNDKVPETVLVQPK------TESDYI---WDQLMA----N-
PRELRIQDMDFTDLGEEDDIDVL-DVD--LGHREAP-----GPPPPPPPTFL----GLPP
PPPPPLL--DSI----------PPPP---VPGNLLAPPPPVFNAPQ--------------
-GLGWSQVPRGQ-P------------TFTKKKKTIRLFWNE--V-----------RPFDW
PCKNNRRC---REFLWSKL-----EPIKVDTSRLEHL---FESKSKELS------VS--K
KTAADGKRQEIIVLDSKRSNAINIGL--TVLP-PPRTIKIAILNFDEY-ALNKEGIEKIL
TMIPTDEEK-QKIQEAQLANPEI----PLGSAEQFLLTLSSISELSARLHLWAFKMDYET
TEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKV
PEVKDTVHK-QSLLHHVCTMVVENFPDSSD-----LY-SEIGAITRSAKVDFDQLQ----
---DNLCQME---RRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRI
INR-------------------------FHSFLLF-------------------------
-----------MGHPP--YAIREVNINKFCRI---ISEFALEY---RTTRERVLQQKQKR
ANHRERNKTRGKMITDSGKFSG-SSPAPPSQPQGLSYAE-----DAAEHENMKAVLQTSS
PSVEDA---APALGVRTRSRASRG----STSSWTMGTDDSPNVT--DDAA--DEIMD---
-----------RIVK--SATQVPSQRV-VPRERKRSR-ANRK------------------
------SLRRTLKSGLTPE------------EARALGLVGTSELQL--------------
------
>gi|147899302|ref|NP_001086147.	Xenopus laevis
----------------------------------MGNAAGSLDMFQARDTRGQSSSGTPP
QKQKEGTPSKL-----------------PRPSSVELEQRFNV------------VLNAMN
LP------------PDKIQVLRQYDQ-DKKWELVCDQERFQVKNPPA---------AYIQ
KLRSYLDTGG---ISRKFKRRV--QESTQVLRELEIS-----LRTN-HIGWVEEFLSPEV
G-----GLDALVDYLSYAQGSFPIDMECSDNGTPEKSKSLQRSLEDINKSSSSPSPTNTP
SRSR------NLTARYTLHNRATMRNSKHANM--KDDVHVCIMCLRAIMNYQSGFS----
-----MVMSHVSCV-NQITL-SLSNKNPRTKA-----------LVLELLAAVCLVRG---
-------GHELILSA----------------FNYFMEVCGEGVRFAK--LMEYFRTEDS-
---------NI---------DFMVACMQFINIVVHSVKN--------------------M
NFRVFLQYEFTLLGLDDFLEILKNTESERLQVQIQAYLDNIFDVNSLLD-----------
---------------DTDTKNEMLEHVEDLQEHLTHVT--EKLQQTENEYVRR-------
------------VAELEKLLDQCRRELSAEKEKLVAQPPQVTQNTV--------------
--------------------------QNTEPVKRGVLWVEP--------AGDTCTDSPPA
TSSP---------------------------PVSPSAIRITLISPLVTSTGDLPSRVDFP
RSTTP-----------------------------------LLPSSLTES----EVLPIT-
-----APSPMPSSGSPVIAPTPLPESQVTPPPSKIDHTHTST------------------
-------------------AQSISGTHAESQSP-------PPPPP---LPSSAE----QP
PPP------PLPISFDVPPPPPL-PETSGIPPP--------PPPPPPPIGAS----GIPP
PPPPPSM--GSSG---------IPPPPPPPSGFGPAPPPPPGGQPA--------------
-ATLNTGVSIKK--------------PIQTKLRMQVLNWVA--L-----------KPTQI
-----------NGTVFTHL----NDEKVLQELDMCDFEENFKTKAQGPNQTTF--SM--K
VKAAQNQPNKVSLIETNRAKNLAITL--RKGGLSPEAITTAIQKYDMQ-TFNMDFLELLA
RFLPTDWER-QQIAKYCRDQKPLD---DLTAEDRFMVHLCSIPRLAERVNTMTFMANFPD
MASRLKPQLDSLIAASMSIKSSEKLKGILELVLAFGNYMNSSKR--GAAYGFRLQSLDVL
LETKSTDRK-QTLLHYMIRVINEKYSHLSG-----FY-SDLHFMDKAATVSLDGLL----
---ADVKSLQTGMEQAQKEF------TKQDDCLILKD----FIKSNMDVLKQLSADAKTA
QEA-------------------------YDAAVGY-------------------------
-----------FGE-----NSKTTPPSTFFPI---FVRFIRAY---KQAAQDLETWKKQE
STAQEVKPE-----------------------------------LAGKQAPQSPVVKSPR
PQVN--------LMAELNKKLQTKEPRVYEPNWAIE----------------DIITD---
-----------LRNQ---------------------------------------------
------PYRRTDMGRRSGK------------KQNSGQPVNTPDIQV--------------
------
>gi|149730272|ref|XP_001493919.	Equus caballus
-----------------------MDRHRPRLHHPAQSSSAGAPCSSSALPRSSRESKMPR
RKGPQHPPPPGGLEEPGEKRPK--FHLNIRTLTDDMLDKF--------------ASIRIP
GS------------KKERPPLSNLKT-AFASNDCSSEMMENIPKPLSENELLELFEKMME
DMNLNEDKKA---PLREKDFSIKKEMVMQYINTASKTGSLKRSRQISSQEFIYELKMGCA
DERLVTCLESLRVSLTSNPVSWVESFGHE-------------------------------
----------GLGLLLDIL--EKLISGKIQEKIVKKNQHKVIQCLKALMNTQYGLE----
-----RIMSEERSL-SLLAK-AIDPEHPNMMT-----------DVVKLLSAVCIV-----
---GEENILEEVLE-----------------ALTTAGEERKIDRFFS--IVEGLRHNSV-
--------------------QLQVACMQLINALVTSPDD--------------------L
DFRLHIRNEFMRCGLKEMLPNLKRIKNDGLDIQLKVFDEH--------------------
---------------KEEDLIEFSHRLEDIRAELDEAY--DVYNMVWNTVKET-------
------RAEGYFISILQHLL--LIRNDYFIRQQYFKLIDECVSQIV--------------
------------------------------------------------------------
-------------------------------------LHRDGMDPDFTYRKRLDLDLSQF
VD-----------------------------------------ICIDQA-----------
-----KLEEFEEKASDLFKKFEKEFTDHQETQAQLQKKEAEINELQ-----AELQAFKSQ
FGALPAGTNT---------SLPLSKENGTSHPA------LPPAPP---LPFCGG----AP
PPP--------------------------------------PPPPPPPLPGMPMPFGGPV
PPPPPLGFLSGRN---------SPPPPALPFGLKPKK-----------------------
--------------------------EFKPEANMRRLNWLK--I-----------RPHEM
T----------ENCFWIKA----NENKYENIDLLCKLENTFCCQQKEKREEDD--FE--E
KKAIKKKIKELKFLDSKIAQNLSIFL--SSFRVPYEEIKMMILEVDET-QLAESMIQNLI
KHLPDQEQL-NSLSQFKSDYN------NLCEPEQFAVVMSNVKRLRPRLSAILFKLQFEE
QVNNIKPDIMAVSTACEEIKKSRSFSKLLELVLLMGNYMNAGSRN-AQTFGFNLSSLCKL
KDTKSADQK-TTLLHFLVEVCEEKYPDILN-----FV-DDMEHLDKASKVSVETLE----
---KNLKQMGRQLQQLEKDLETFP--PPEDLHDKFVTKMSSFVISAKEQYEKLSKLHENM
EKL-------------------------YQSIMQY-------------------------
-----------YAI-----DVKKVSVEDFLTD---LNNFRTTV---MQAIKE--NVKKRE
AEEREKRARIAKELAEKERLERQQKKKRLL--------------EMKTEGDETGVMDSLL
EALQSG------AAFRDRRKRTPKPKDIRQSLSPMSQRPILKVCNHENQK--GQLTE---
-----------GSRS--HYNINCNSAR-TPVAKELNYNLDTPTSTGRIK-----------
------AVEKKEACNVESN------------RKKEMELLGSVSKNESIPEVEALLARLRA
L-----
>gi|24639048|ref|NP_569900.3|	Drosophila melanogaster
------------------------------------------------------------
-----------------------------MPSVDELDTKFAE------------LVEELD
LTAPNKEAMLSLPAQKKWQIYCSRKL-PLDAAD--GPDAAAVTQPPTAEHYIERLKELVV
HISLSPEDSP---SHELGNRL---DGHAAFVDALKTA-----LRTS--------------
------THSFVLRFVELD------------------------------------------
----------GLPALLDLL--LQLDIRVANSP----LHTSLIGCIKALMNNSMGRA----
-----HVLAHPTAI-DTIAR-SLAADNIRTKI-----------AALEILGAVCLVPG---
-------GHRKVLQA----------------MLHFQVFATERTRFQS--IVNDLDRSTY-
-----AYRDNV---------NLKTALMSFVNAVLNYGPGQEN-----------------L
EFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMV--------------------
---------------RAEDEKEFARRFKEEHVDTKSAG--SMFELLRRKLSHS-------
------PAYPHMLSLLQHML--LLPYTGHCTEHWLLIDRVVQQIVL--------------
-----------------------------------QVEQRPNSDLIVD-PDDPEKQLKLA
AESPVHDPDVAPL------------------QIDVAKLVRLLVKEEQLTQARKRADELER
EN-----------------------------------------FDVQSRL---AKKEQEL
DLRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEMRAEDLQ-----HRLISEQQE
-------------------RARLERLVTEGS--------IPDDQK---VAGLTGCNGAVS
PPP---------------APPMLKA----------------IPPPPPPMAPS----MMPP
PPPPCPG---------------APPPPPSMAQTMAPAPPKV-------------------
------DLPKKN--------------VPQPTNPLKSFNWSK--L-----------PDAKL
-----------QGTVWSEL----DESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLR
VTGKAAKQKVLSVIDGRRAQNCTILL--SKLKMSDMEISKAILSMDSNEQLQLDMVEQLL
KFTPSAEER-ALLDEHSEDIE------SLARADRFLYEISKIPHYEQRLKSLHYKKRFML
TINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGAR--GNASGFRLASLNRL
ADTKSSAAKGTTLLHYLVQVIERKFKDLLK-----LE-DDIPHVREASKVSLGEMD----
---KDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDM
KTR-------------------------FDRAVRL-------------------------
-----------FGE-----DGSVLQPDEFFGI---FDSFLAAF---AEARHDNESFRRRQ
EEEEKRAKQEAELKK-----------------------------RTIERKNKTGLMTSVA
RNLG------------------------LKSGSSNGDPDSPAKG-GDNKGEFDDLIS---
-----------ALRTGDVFGEDMAKFK-RSRKARVLNGGGSSTGHT--------------
------SPPRHGSLQREES------------GRERERTVRRQ------------------
------
