>gi|73963770|ref|XP_868316.1|	Canis familiaris
------------------------------------------------------------
-------------------------------MALTSFLPAPTQLSQDQLEAEEKARSQRS
R---------QTSLVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDAEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKVRIFNSVYT----------------E
DGEA-----------RERDEIRHDRRK-ERQHDRNLSRAAPDKRSK---LQRNENRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----SKGMDSGFAGGEDEIYNVYDQAWRGGK--
DMAQ----NIYRPS-KNLDKDM----YGDDLEARIK----TNR-----------------
------F----VPDKEFSGSDR--RQRGREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSSRP-----K----EHEHEGKKRRKE------------------
--
>gi|47222671|emb|CAG00105.1|	Tetraodon nigroviridis
------------------------------------------------------------
-------------------------------MALTSFLPAPTQLSQDQLEAEERLRAQKS
Y---------STALVSSRKEPPPYGHRKGWVP---RSIEDFGDG----GAFPEIHVAQFP
LEMGRK---KVTSN-ALAVQVDAEGKIKYDAIARQGQNKDKVVYSKYTDLLP---KEVLN
EDVPELQK--PDEEAVQELTEKTRAALNKQVSQK------IAAAMP--VRAADKQAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVEK
KMAQKEKEKKEEKLRELAQIARDRRAGIKSHGDKGG-----------------------E
DSEA-----------RERDEIRHDRRR-DRQHDRNISRAAPDKRSK---LQRDQDRDISE
LIALGVPNPR--SSSEVQYDQRLFNQ-----SKGMDSGFAGGEDESYNVYDQPFRGGR--
DMAS----NIYRPS-KNIDKDA----YADDFDTLMQ----NNR-----------------
------F----VPDKEFSGAD---HGQRREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSTSSRS-----K----DDYHE-KKRRKE------------------
--
>gi|157105626|ref|XP_001648953.	Aedes aegypti
------------------------------------------------------------
-------------------------------MSLSSILPAPANPIWDRDDERKHVAKGTP
S---------MGALVSAKIAAPPYGQRKGWVP---RTEADFGDG----GAFPEIHVAQYP
LGLGAPGNANKKSN-ALAVQLDQSGKVKYDAIARQGHSKDKIVYSNINQLLP---AEVLA
EDAEELRM--PDQEAIDEITENTRKALEKLTNQK------IVSAMP--VRAAEKQAPAQY
IR-YTPSQQGDAFNSG----------------AKQRVIRMVEAQVDPMEP--PRF---RI
NKKI-------PRGPPSPPAPVLH--S-PTRKVTVKEQREWKVPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QQVHINEKFAKMAEA-LYIADRKAREAVEARAQLEK
KLAQKEKEKKEDMLRQMAQRAREERAGIRHPGEMAG-----------------------G
SGSAGGDPSLIPADLRERDEIRAERHR-ERARDRNLARAAPDKRSK---LQRERERDISE
QIALGMPAKSS-VGGEAQFDQRLFNT-----SKGMDSGY--GDDEAYNVYDKPWRDAG--
TLGT----HLYRPS-KALDNDN----YGADLDQIMN----TQR-----------------
------F----VPDKEFSGTDR-SAQAARQGPVQFEK--------EEDPFGLDQFLNMAK
KAP--------KRKEDAMAG-----S----SNRDKDRKKRRD------------------
--
>gi|146262080|gb|ABQ15152.1|	Schistosoma mansoni
------------------------------------------------------------
-------------------------------MSLLGQLPAPIQKGSDDYGTALNLNVGSR
-------------VLVAKSTIPPYGHRKNWVP---RNQEDFLDG----GAFPEIHVPQYP
LGMGQE---KNISN-ALVIKTDKDGRIRYDELVRQGHSKDRIIYSKFSDLLP---KPI-D
DDDPEFNK--PSQETIEETTEKTRKALESLVEMK------VAAAAP--VRRAEKTNPAEY
IR-YTPSQQGAAFNSG----------------AKQRLVRMVEMQKDPMEP--PKF---KI
NQKI-------PRGPPSPPPPLMH--S-PARKVTVKEQQDWKIPPCISN------WKNPR
GYTIPLDKRVAAD-GR----GL--QTVHINENFAKLAEA-LYTADRKAREAVEMRAQIER
KVAQKEKERKEEQLQRIAQQARESRAGLRRPGAT-------------------------E
GGDN-------DPELMDREELRRDRAR-DRARERNLARSNNEAKAK---IEKDKERDISE
QIALGLPNPRFNSTNESLFDQRLFNQ-----SKGLDSGFEGGADDLYNIYDKPWRGDS--
ELVN----HIYRP--RQKDTDA----YGTDLDALKK----TKR-----------------
------F----VPDREFSGTD---HSRRLDGPVQFER-------DEEDPFNLSKFLSKVK
KAE--------KRPGEGTSG-----TDISNRDTTHRKRDRKD------------------
--
>gi|119902969|ref|XP_001252076.	Bos taurus
------------------------------------------------------------
---MCSESQQLSARERPAPRCCRSRWKKRKKMALTSFLPAPTQLSQDQLEAEEKARSQRS
R---------QTSLVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDAEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PGXRSHXRDNRKDKSSLRKIC---------IAEGCS--SHASPSSXXTGS
CS-VYPIHT-ISTRSG------------------FQLWRXTESYSDGGNA--ERS---NG
ASKV-------QDXXENSSGTTFS--S-CTCHAFSXPKDDREGAARVEDSSMYFKLEKCK
GLYNSIRXTSGCR-WK----RT--ADSSHQXKFCKTGRSPLHCXSKGSXSSGNACSSREK
DGSKRKGKTXRETXRNGPESQREKSWDQNPCGKRGRGGT--------------------X
EGXN-------PAXPAKRETAXPEPLQ---GSSRQEVETAEKXKSR---HQXSHCSRCAQ
PSDFQXSSVRPKALQPVQGYGQWFCR-----WRRXNLQCLXSSLERWKRYGPEYLQAQXK
SGQG----HVWRXP-RSQNKDXQICSRXGVFWFRPX----TKR-----------------
------------PRR---------TSSVXGGSFRFG-----------QIFGRSQATRWLX
KT---------LRXQPS-------------QGTXAXRQKEEEGV----------------
--
>gi|109084469|ref|XP_001096395.	Macaca mulatta
--------------------------------MGADELNRNEWYSRSKNYKSQKAFRPER
LRIARSFLSAPHHLERPAPRCCRSRWKKRKKMALTSFLPAPTQLSQDQLEAEEKARSQRS
R---------QTSLVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
ISRL-------FSIFPSSSKLLLE--L-YGKLMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK-------------------------E
DGEA-----------RERDEIRHDRRK-ERQHDRNLSRAAPDKRSK---LQRNENRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----SKGMDSGFAGGEDEIYNVYDQAWRGGK--
DMAQ----SIYRPS-KNLDKDM----YGDDLEARIK----TNR-----------------
------F----VPDKEFSGSDR--RQRGREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSSRP-----K----EHEHEGKKRRKE------------------
--
>gi|58270240|ref|XP_572276.1|	Cryptococcus neoformans
------------------------------------------------------------
----------MIHSHNNNLSFCSQLITVRKMAALTRALPAPLHTSTTEYEEAPAPLPTTP
-----------------GPQLPKYGQRKGWKP---KTAADFNGG----GAYPECHVAQYP
LDMGKKN--KGQGS-TLALQVDQDGLVRYDAIAQHGRAPGSRVQSSFKDLVPLANRTDVT
ESERQMER--PDDLSVAETAERTRLALERITHGK------IKAAQP--KHVPKTNSDATY
IR-YTPANQSA---DE----------------GKQRIIKMTEVQEDPLEP--PRF---K-
HKKI-------PRGPAEPPPPVLQ--S-PPRAATAQDQKDWMIPPCISN------WKNNK
GYTIPLDKRLAAD-GR----GL--QDVHINDNFAKFSES-LYIADRHIREEVRARAQLQQ
LLAQKQKTSKEEELRLLAQRAREDRSGLSSSVSGSVAAASASRLPAETGINLGGYGSESG
SEEESDEEEEDEEAIRERNIVREEKRR-EREKEMRMSNMGSEMRAKM--LAKEANRDISE
KIALGLAKPS--ASKETLLDSRLFNR------EALSTGF--ASEDSYNLYDKPLFAGS--
SAAA----AIYRPAGSSRNDES----FGGGTEEGIKEEMSKDR-----------------
------F-QLGNATRGFEGAE---GVEAREGPVQFEKDTIVALDGSADPFGVEQFMDAAR
RGG--------KRTAED-------------RDEERRKRARDE------------------
--
>gi|149633204|ref|XP_001505367.	Ornithorhynchus anatinus
MAVLIIMDKSGRLRAEGQPKPARCGAVRRPGSDPSRAPPARTAARAALRRPKTTSPRGRC
APGACAPRRSPGRWGRGRP----GGRKKRKKMALTSFLPAPTQLSQDQLEAEERARSQRA
R---------QTALVASRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK-------------------------E
DGEA-----------RERDEIRHDRRK-ERQHDRNLSRAAPDKRSK---LQRNENRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----TKGMDSGFAGGEDEIYNVYDQAWRN-K--
DMAQ----SIYRPS-KNVDKDM----YGDDLEARIK----TNR-----------------
------F----VPDKEFAGSDR--RQRGREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSGRP-----K----EHDHEGKKRRKE------------------
--
>gi|62868248|emb|CAI59265.1|	Echinococcus multilocularis
------------------------------------------------------------
-------------------------------MSLLSQLPAPTQRI---IDAQTDLIANPS
H------------VIVHKSSLPPYGHRKHWFP---RNEDDFGDG----GAFPEIHMPQYP
LGMGRQ---KSSSN-ALVMKTDKDGKVRYDELVRGGHAKDRIIYSKFTDLLP---KPI-D
EDDEELQK--PSKETVEETTEKTRKALEALVEQK------VAASLP--VRKAERTGPAEY
IS-YTPAQQGPAFNSG----------------AQQRLVRMVEAQRDPMEP--PRF---KI
NQKI-------PRGPPSPPPPLMH--S-PSRKVTAKEQAEWKIPPCISN------WKNPR
GYTIPLDKRVAAD-GR----GL--QTTHINENFAKLAEA-LYTADRKAREAVELRAQIER
KVASKVRERKEEQLQKIAMEARAARAGLRRGSNA-------------------------D
DESE----------MASRDQIRRERAR-DRAHDRNLSRVGAEGKVR---TQRDKDRDISG
QIALGMPNPRLNANSESMFDQRLFNQ-----SRGMDSGFAGGEDDLYNIYDKPWRQES--
NFGT----HIYRP--RQTDTDT----YGNDLEAAGK----QRQ-----------------
------F----VPDRGFAGAD---RSRHLEGPVQFER-------GGEDPFNVSTFLLEAK
KAD--------KRPGDSSTTSN--------RDTTYRKRERRD------------------
--
>gi|115693359|ref|XP_001188665.	Strongylocentrotus purpuratus
------------------------------------------------------------
---------------------------------------MPSRLRV--------------
-------------VSVSRNAAPPYGHRKGWVP---RSLADYGDG----GAYPEIHIAQYP
LDMGRTK--TNQSN-AVAKTVDAEGKVRYDALARIGHGKDKVVHSRPQDLLP---RVMGD
DDDPDLQK--PDEESIEETAEKTRSALEKIVQSK------ISAALP--VRHAEKTAPAQY
IR-YTPSQQGLAFNSG----------------AKQRVIRMVEAQKDPMEP--PRF---KT
NKKI-------PRGPPSPPAPVMH--S-PTRKVTVKEQQEWKIPPCISN------WKNQK
GYTIPLDKRLAAD-GR----GL--QNPQINENFAKLAEA-LYIADRKAREAVEMRAGMER
KVAQREKEKHEEQLRAIAAKAREDRAGIKSAMD--------------------------N
DDDV-----------RERDKIRDERHR-DRQRERNFARAAPDKRSR---LEKQRERDVSE
KIALGLPNAGAGRSDDAQFDQRLFNQ-----SKGLNSGFGGGEDESYNVYSEPWRKDQ--
NVAS----NLYRPS-RNADKDV----YGDDLDNLIK----NKK-----------------
------F----VPDKGFAGAD---SSRRRDGPVQFERE------EEEDVFGLDNFFKTVK
KAD--------KRQADERN------RDDYERGSSSSSKRRKDY-----------------
--
>gi|126282237|ref|XP_001367089.	Monodelphis domestica
------------------------------------------------------------
-------------------------------MALTSFLPAPTQLSQDQLEAEERARSQRS
R---------QTALVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDAEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK-------------------------E
DGEA-----------RERDEIRHDRRK-ERQHDRNLSRAAPDKRSK---LQRNETRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----TKGMDSGFAGGEDEIYNVYDQPWRSGK--
DMAQ----NIYRPS-KNLDKDM----YGDDLEARIK----TNR-----------------
------F----VPDKEFSGSDR--RQRGREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSSRP-----K----EHEHEGKKRRKE------------------
--
>gi|149737560|ref|XP_001492173.	Equus caballus
----------MTDIALGYYRPSNMSGEGSSASGPRLTTEQNRIVRLFKELQIPEGPSARR
LRVACSFLSPPCRGERPAPRRCRSRWKKRKKMALTSFLPAPTQLSQDQLEAEEKARSQRS
R---------QTSLVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDAEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRRAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK-------------------------E
DGEA-----------RERDEIRHDRRK-ERQHDRNLSRAAPDKRSK---LQRNENRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----SKGMDSGFAGGEDEIYNVYDQAWRGGK--
DMAQ----NIYRPS-KNLDKDM----YGDDLEARIK----TNR-----------------
------F----VPDKEFSGSDR--RQRGREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSSRP-----K----EHEHEGKKRRKE------------------
--
>gi|50310345|ref|XP_455192.1|	Kluyveromyces lactis
------------------------------------------------------------
----------------------------MSFRTLSSLLPSPQN-----------------
------------------------------------------------------------
---------SEVSE-SSAFSRQSKENIK-DTIILDKLRPENLPVASISDFVP------LR
QRDISLEAPFPSTSQINQTYVKTKAFLDSLLTKK------SSLQLS-------SIANKDI
VK-R----EAISSVKS----------------GTQRSVKVIEHKKDPLQP--VTH---R-
KRKV-------VVPSEEIQAPILHKSDDPSIKPTKEELDKWRIPSAISN------WKNPN
GFAISLDNRVAIE-SI----KTDCPDNDKKDNFLLLSEA-LDEAEREARQRINIKQEAYK
ELEKEETLKKEQRLRHLAERARQDRENRRQY----------------------------E
NEDH-----------YVREMERNQRRRAERELERSNKMSTAEKLRR---LAYQQGRDVSD
KVVLNAAKAT--ETPDLQYDSRLFKK-----A---ASSVASSSN---QIFDHPLFNNS--
QID-----NIYRPT------------TGSNLENEDI----VDR-----------------
-----------LS-----------NKKGRTGPVEFSA------------A------DDGK
NAEQN------EEDNEHARE----------YGLQVRKKPHTS------------------
--
>gi|5241|emb|CAA44455.1|	Saccharomyces cerevisiae
------------------------------------------------------------
--------------------------------MFSNRLPPPKH-------------SQGR
V---------STALSSDRVEP---------------------------------------
---------AILTD-QIAKNV------------------------KLDDFIP------KR
QSNFELSVPLPTKAEIQECTARTKSYIQRLVNAK------LANSNN--------RASSRY
VTETHQAPANLLLNNS-------------------HHIEVVSKQMDPLLP---RFVGKKA
RKVV-------APTENDEVVPVLH--MDGSNDRGEADPNEWKIPAAVSN------WKNPN
GYTVALERRV----GK----ALDNENNTINDGFMKLSEA-LENADKKARQEIRSKMELKR
LAMEQEMLAKESKLKELSQRARY------------------------------------H
NGTP-----------QTGAIVKPKKQT------------STVARLKE--LAYSQGRDVSE
KIILGAAKRS--EQPDLQYDSRFFTRGQMPPPKGMKTRFMTTH----------CSSNK--
-ILK----AYTRPTTKS---------WTKRSMLRVK------------------------
-----------VP-------------VVLTAPFSL--------------LKLNPMINRIT
MA---------PRPRMSTR-----------KTKHSCA-----------------------
--
>gi|83771403|dbj|BAE61535.1|	Aspergillus oryzae
------------------------------------------------------------
--------------------------MTSIAEGLFKSLPKPKYTGEDE-EIPHHAQPRGP
RV-VGADQIDESQIVLRKTGPPPYGNRTGWRP---RAPEDFGDG----GAFPEILVAQYP
LDMGRKGS-SSTSN-ALAVQVDAEGKVKYDAIARRGHSDNRIVHASFKDLIPL--RQRVD
MGEISLDR--PSEEEVAEQMEKTKNALANLVSGA------VAAQKPKNVKGGSRAEPT-F
VR-YTPANQ-MGDNSR----------------KNDRIMKIVERQQDPMEP--PKF---K-
HKKI-------PRGPPSPPPPIMH--S-PPRKLTAEDQEAWKIPPPVSN------WKNPK
GYTVPLDKRLAAD-GR----GL--QDVTINDKFAQFAEA-LFTADRHAREEVRLRAQMQQ
KLAEKEKAQKEEHLRALAQKAREERATSSRRDSRAVSRSRSRSRSVSRSPSPYSDRSRTP
SDDE--------QAARERERMRRERRQ-ENERQLRQSRMGTERRIQA--MAREQNRDISE
KVALGLAKPT--QSSETMWDSRLFNQ-----TSGMDSGF--NED---NPYDKPLFAAQ--
DAIN----SIYRPR-AQVDADDDEGGAEGEMSRIQK----SNR-----------------
------FEVLGKAKEGFRGAA---DAEARDGPVQFEK-------DTTDPFGIDSMIADVT
GGAGQ------KRYGIQEVD----------REDRGSKRARVDEE----------------
--
>gi|66513194|ref|XP_623623.1|	Apis mellifera
------------------------------------------------------------
-------------------------------MSLTRLLPAPSQVAWDTKYEARKQKLRHT
P---------VSALVKAVITAPPYGQRKGWVP---RNPEDFGDG----GAFPEIHVAQYP
LGMGMKGK-ETTSN-ALAVQLDAQGKVKYDVIARQGHSKDKIVYSKLSDLLP---SEITS
EEDPSLQR--PPNEEIEELTEKTKKALEKITRSK------IAAAMP--VRCAEKQAPAQY
IR-YTPSQQGQSFNSG----------------AKQRVIRMVEAQIDPLEP--PKF---KI
NKKI-------PRGPPSPPAPVMH--S-PTRKVTVKEQKEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QQVHINENFAKLAEA-LYIADRKAREAVEMRAQLEK
KLAQKEKEKKEDHLRQLAQKAREERAGLKSAAME-------------------------K
SEES-----------RERDQLRQERHK-DRARERNLARAAPDKRSR---LQRERERDISE
QIALGLPAKSIPNSGEAQFDQRLFNT-----SKGMDSGF--GHDDEYNVYDKPWKDSN--
SIGS----HIYRPS-KNIDKDT----YGDDLEKLVK----TNR-----------------
------F----VPDKEFSGTD---RSTTRSGPVQFEK-------DEEDPFGLDQFLKQAK
RASSSTTTTT-KRKDERE------------QRRDDRDKRRKH------------------
--
>gi|91076668|ref|XP_971504.1|	Tribolium castaneum
------------------------------------------------------------
-------------------------------MELSSLLPAPIQPVWDRDDERRQQNATTQ
R---------STSVVTAQSIAPPYGQRRGWVP---RVHTDYGDG----GAFPEIHVAQYP
LDMGRKGK-ESTSN-ALAVQLDAEGKVKYDVIARQGHGKDKIVYSKLSDLLP---VEVTT
ENDPSLAK--PSQEEIEDITEKTRQALQRLTNSK------IAAAMP--VRCAEKQGPAEF
IR-YTPSQQGAAFNSG----------------AKQRVIRLVEAQVDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVLH--S-PTRRVTVKEQKEWKIPPCISN------WKNAK
GYTVPLDKRLAAD-GR----GL--QQLHINENFAKLAEA-LYIADRKAREAVETRAQLEK
KLAQKEKEQKEEHLRQLAQKARDERAGIKVADAKI------------------------T
DEEE-----------REREMLRQDRHK-ERARERNLARAAPDKRSK---LKRERERDISE
QIALGMPARGV-SSNEVQFDQRLFGQ-----AQGLGHGY--GDDDAYNVYDKPWREGG--
SMAN----HLYRPS-RNVDKEV----YGEDLEKIVK----TNR-----------------
------F----VPDKEFSGTD---RNAPRSGPVQFEK--------EEDPFGLDQFLSQAK
RAS--------KRKEPE-------------RRDERDKRKRRD------------------
--
>gi|62858311|ref|NP_001017145.1	Xenopus tropicalis
------------------------------------------------------------
-------------------------------MALASFLPAPTQLSQDQLEAEEKLRAQKS
R---------QTALVASRRESPPYGHRKGWVP---RSLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAVQVDAEGKIKYDAIARQGQSKDKVIFSKYTDLVP---KEVMD
EDDPELQR--PDEETIKELTEKTRQALEKSVSQK------IAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKKEEKLRELAQIARERRAGIKSHTDK-------------------------E
DGEA-----------REREEIRHERRK-ERQHERNLSRAAPDKRSK---LQRNEERDISE
QIALGIPNQR--TSSEVQYDQRLFNQ-----SRGMDSGFAGGEDEVYNVYDKPWLGNK--
KLAQ----NIYRPS-KNTDNDV----YGDDLDTLVK----TNR-----------------
------F----VPDKDFSGAD---RRQRHEGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSGRA-----K----DHDHDMKKRRKE------------------
--
>gi|45188234|ref|NP_984457.1|	Ashbya gossypii
------------------------------------------------------------
----------------------------MNSAPFSTLLPPPKKESSP-------------
-------------TVASAHQSP----------------ENQGD-----------------
---------------------EPVAGIVFDSLQPDG-----IPNVSFQDFIP------IR
QRDFNMEIPLPSKQDIEQTFQRTKAYFDKLLNNK------PATNSR--PSTDARSGKGNY
IE-YKTTD---ALTNK----------------STSRIIKIVDHVADPLQP--SQI---KR
KKVV-------APPTDEPVAPILH--S-ATEKLTKEQREQWRIPSAVSN------WKNPN
GYAIDLEKRIAID-GRYNREGT--AIPAVNEKLLELTNA-LEEAESKAREEVRNRAEARK
QEAEQQVRLKEDKLRELAQRSREERQRKRRQPIDHEE----------------------Y
DESA-----------IIRQTERNEKRD-QMKNDMRLSKLSTADRLRV--LAHAQGRDVSE
KIILGAAKPS--EVPDVHYDSRLL-------TKGAGTAVPGAPE---QVYDGPLFAQN--
AMDR-----LYKPA-RFTGPEN------DALDILSK----MTS-----------------
------------------------EQR-------FED------------QDPGTSVDQQQ
TSPGM------QKSDAKQ------------DSEHDLKRT---------------------
--
>gi|6912676|ref|NP_036377.1|	Homo sapiens
------------------------------------------------------------
-------------------------------MALTSFLPAPTQLSQDQLEAEEKARSQRS
R---------QTSLVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK-------------------------E
DGEA-----------RERDEIRHDRRK-ERQHDRNLSRAAPDKRSK---LQRNENRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----SKGMDSGFAGGEDEIYNVYDQAWRGGK--
DMAQ----SIYRPS-KNLDKDM----YGDDLEARIK----TNR-----------------
------F----VPDKEFSGSDR--RQRGREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSSRP-----K----EHEHEGKKRRKE------------------
--
>gi|114654179|ref|XP_001165652.	Pan troglodytes
------------------------------------------------------------
-------------------------------MALTSFLPAPTQLSQDQLEAEEKARSQRS
R---------QTSLVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK-------------------------E
DGEA-----------RERDEIRHDRRK-ERQHDRNLSRAAPDKRSK---LQRNENRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----SKGMDSGFAGGEDEIYNVYDQAWRGGK--
DMAQ----SIYRPS-KNLDKDM----YGDDLEARIK----TNRCQAIQLNFSVYTGESKV
VHSFFSFSLDLFPTRSFLVQTV--DREAEKDQFSLRK----------ILLVWTSFWKKPN
SMVAL------KDPQIAAAP-----RNMSMKARRGGRNRHRSLQSE--------------
--
>gi|90075908|dbj|BAE87634.1|	Macaca fascicularis
------------------------------------------------------------
-------------------------------MALTSFLPAPTQLSQDQLEAEEKARSQRS
R---------QTSLVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKVTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK-------------------------E
DGEA-----------RERDEIRHDRRK-ERRHDRNLSRAAPDKRSK---LQRNENRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----SKGMDSGFAGGEDEIYNVYDQAWRGGK--
DMAQ----SIYRPS-KNLDKDM----YGDDLEARIK----TNR-----------------
------F----VPDKEFSGSDR--RQRGREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSSRP-----K----EHEHEGKKRRKE------------------
--
>gi|156544946|ref|XP_001607473.	Nasonia vitripennis
------------------------------------------------------------
-------------------------------MSLSSILPAPTQVVWDREDEAREAKLRQR
P---------VSALVKAVVSAPPYGQRKGWIP---RNEDDFGDG----GAFPEIHVAQYP
LGMGEKGK-ETTSN-ALAVQLDAQGKVKYDLIARQGHSKDKIVYSKLTDLLP---AEILT
EDDPNIQK--RSEEEAEETTEKTKRALEKITESK------IAAAMP--VRRAEKQGPAQY
IR-YTPSQQGQSFNSG----------------AKQRVIRMVEAQVDPMEP--PKF---KI
NKKI-------PRGPPSPPAPVMH--S-PTKKVTVKEQKEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QQTHINENFAKLAEA-LYIADRKAREAVEMRAQLEK
KLAQKEKEKKEDHLRQLAEKARNERAGLKTAAVL-------------------------G
ELTAKLKHLIYITKIRDREQIRQDRHK-ERARERNLARAAPDKRSR---LQRERERDISE
QIALGMPAKNVNTTGDQAFDQRLFNT-----TKGMDSGY--GHDDEYNVYDKPWRDTS--
SIGS----HIYRPS-KNIDQDN----YGEDLEKLKS----TSR-----------------
------F----VPDKEFSGTDR--TGAGRSGPVQFEK-------EEEDPFGLDQFLKQAK
RASNTAPTTATKRKDDGHS-----------KKDDNRDKRRKH------------------
--
>gi|125981855|ref|XP_001354931.	Drosophila pseudoobscura
------------------------------------------------------------
-------------------------------MSLSSLLPTPTNAVWDREDERRLAAKGAP
Q---------IGALVSAKIAAPPYGCRKDWVP---RTEADFGDG----GAFPEIHVAQYP
LGLGAPGTMGKKSD-ALAVRLDDKGKIKYDAIARQGHGKDKVVYSSISQLLP---AEVLA
EDADELQR--PDEESVAETTEETRLALEKLTNQK------ITSALP--VRHAQKAGPAQY
IR-YTPSQQGDAFNSG----------------AKQRVIRMVEAQLDPMEP--PKF---RI
NKKI-------PRGPPSPPAPVLH--S-PSRKVTVKEQKEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QQVHINEKFAKMAEA-LYIADRKAREAVEARAQLEK
KLAQKEKEKKEDMLRMMAQRAREERAGLRNPETASDPIGGGA-----------------N
GVEA-----------RERNDLRAERQR-ERQRDRNLQRAAPEKRSK---LQKERERDISE
QIALGLPAKSA-GNGETLFDQRLFNT-----TKGMDSGY--GDDEAYNVYDKPWRDAN--
TLGN----HIYRPS-KQADSDN----YGGDLDAIVN----TKR-----------------
------F----VPDKQFSGASRETAGAVRSGPVEFEK--------EEDPFGLDQFLNMAK
KAP--------KRAEEKSER----------NSQSERKRSRRD------------------
--
>gi|24640727|ref|NP_511093.2|	Drosophila melanogaster
------------------------------------------------------------
-------------------------------MSLSSLLPTPTNAIWDREDERRLVARGAP
K---------IGALVSAKIAAPPYGQRKDWVP---HTDADFGDG----GAFPEIHVAQYP
LGLGAPGNVGKKSD-ALAVRLDDKGKVKYDAIARQGHGKDKIVYSSISQLLP---AEVLA
EDADELQR--PDEETVMETTEETRLALEKLTNQK------ITSALP--VRHAQKAGPAQY
IR-YTPSQQGDTFNSG----------------AKQRVIRMVEAQLDPMEP--PKF---RI
NKKI-------PRGPPSPPAPVLH--S-PSRKVTVKEQKEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QQVHINEKFAKMAEA-LYIADRKAREAVEARSQLEK
KLAQKEKEKKEDMLRMMAQRAREERAGLRNPEAAEPSGSGA------------------T
GSEV-----------RERNDLRAERQR-ERQRDRNLQRAAPEKRSK---LQKERERDISE
QIALGLPAKSA-GNGETLFDQRLFNT-----TKGMDSGY--GDDEAYNVYDKPWRDSN--
TLGA----HIYRPS-KQADSDN----YGGDLDAIVN----TKR-----------------
------F----VPDKQFSGASKEAAAGQRSGPVEFEK--------EEDPFGLDQFLNMAK
KAP--------KRAEEKNNE-----R----SSHSDRKRSKRD------------------
--
>gi|109479738|ref|XP_001059272.	Rattus norvegicus
-----------------------------MVFSTLLSQNQQAATIPTKRTTRPRVPFGQS
ACAVSIFHSVPRSRARIAPRRCGLRRKKRKKMALTSFLPAPTQLSQDQLEAEERARSQRS
R---------QTSLVSSRREPPPYGYRKGWIP---RLLEDFGDG----GAFPEIHVAQYP
LDMGRK---KKMSN-ALAIQVDPEGKIKYDAIARQGQSKDKVIYSKYTDLVP---KEVMN
ADDPDLQR--PDEEAIKEITEKTRVALEKSVSQK------VAAAMP--VRAADKLAPAQY
IR-YTPSQQGVAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVER
KMAQKEKEKHEEKLREMAQKARERRAGIKTHVEK-------------------------E
DGEA-----------RERDEIRHDRRK-ERQHDRNLSRAAPDKRSK---LQRNENRDISE
VIALGVPNPR--TSNEVQYDQRLFNQ-----SKGMDSGFAGGEDEIYNVYDQAWRGGK--
DMAQ----SIYRPS-KNLDKDM----YGDDLETRIK----TNR-----------------
------F----VPDKEFSGSDG--RKRGREGPVQFEE----------DPFGLDKFLEEAK
QHGGS------KRPSDSSRP-----K----EHEHEGKKRRKE------------------
--
>gi|157017371|gb|EAA09195.3|	Anopheles gambiae
------------------------------------------------------------
-------------------------------MSLSTVLPAPSNPVWDRDDER---KMKTP
S---------MGALVSAKVAAPPYGQRKGWIP---RTDADFGDG----GAFPEIHVAQYP
LGMGAPGNASKKSN-ALAVQLDQTGKVKYDAIARQGHSKDKIVYSNINQLLP---AEVLA
EDSEELQM--PDQETINEITENTRKALEKLTNQK------IVSAMP--VRAAEKQAPAQY
IR-YTPSQQGDAFNSG----------------AKQRIIRMVEAQVDPMEP--PRF---RI
NKKI-------PRGPPSPPAPVLH--S-PTRKVTVKEQKEWKVPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QQVHINEKFAKMAEA-LYIADRKAREAVEARAQLEK
KLAQKEKEKKEDMLRQMAQRARDERAGIRHPDAAGESLAG-------------------G
SGTT---------DLRERDEIRAERHR-ERARDRNLARAAPEKRSK---LQRERERDISE
QIALGMPAKTN-LAGESQFDQRLFNT-----SKGMDSGY--GDDEAYNVYDKPWRDSG--
TLGQ----HLYRPS-KSIDNDA----YGADLDKIVN----TNR-----------------
------F----VPDKEFSGTDR-SAQNVRQGPVQFEK--------EEDPFGLDQFLSMAK
KAP--------KRKEDSFAGASGSGS----SSRDKDRKKRRD------------------
--
>gi|70985064|ref|XP_748038.1|	Aspergillus fumigatus
------------------------------------------------------------
--------------------------MTSVAEGLFKSLPKPKYTGEDE-EVPQHAQPRGP
RI-VGADQIDQSQIVLRRTGPPPYGNRAGWRP---RAAEDFGDG----GAFPEILVAQYP
LDMGRKGT-ATTSN-ALAVQVDAEGKVKYDAIARRGHSENRIVHASFKDLIPL--RQRVD
MGEISLDR--PSEEEVQAQMEKTKNALASLVEGA------VAAQKPKNVKGGRRAEPT-F
VR-YTPANQ-MGDTTR----------------KNDRIMKIVERQQDPMEP--PKF---K-
HKKI-------PRGPPSPPPPIMH--S-PPRKLTAEDQEAWRIPPPVSN------WKNPK
GYTVPLDKRLAAD-GR----GL--QDVTINDKFAQFAEA-LFTADRHAREEVRLRAQMQQ
KLAEKEKAQKEEHLRALAQKAREERAASNRRDSRARSHTRSASRSPSAYSRSATPS---D
DEEA----------ARERERIRRERRQ-DAERQLRQSRMGTERRIQM--MAREQNRDISE
KVALGLAKPT--QTSESMWDSRLFNQ-----TSGLQSGF--NED---NPYDKPLFAAQ--
DAIN----SIYRPR-AQLDVDDEEG-AEGEMSKIQK----TNR-----------------
------FEVLGKAKEGFRGAA---EAEARDGPVQFEK-------DTTDPFGIDSMIADVT
GGAGQ------KRYGIQEVE----------REDRGSKRARVDDD----------------
--
>gi|126631268|gb|AAI33123.1|	Danio rerio
------------------------------------------------------------
-------------------------------MSLTSFLPAPTQLSQDQLEAEERSQAYRS
Q---------STALVSTRRDPPPYGFRKSWVP---RALEDFGDG----GAFPEIHVAQYP
LEMGRK---KRTSN-ALAVQVDAEGKIKYDAIARQGQSKDKVIFSKYTDMLP---KEVLN
QDDPELQK--PDEEAVRELTEKTRLALEKQVSQK------IAAAMP--VRAADKQAPAQY
IR-YTPSQQGLAFNSG----------------AKQRVIRMVEMQKDPMEP--PRF---KI
NKKI-------PRGPPSPPAPVMH--S-PSRKMTVKEQQEWKIPPCISN------WKNAK
GYTIPLDKRLAAD-GR----GL--QTVHINENFAKLAEA-LYIADRKAREAVEMRAQVEK
KMAQKEKEKKEEKLRELAKMARDRRAGIKPHGDKGG-----------------------E
DSEV-----------RERDEIRHDRRK-DRQHDRNISRAAPDKRCR---SFRGTKTGTSV
SSLLSASRTR----------APLVRL-----SMTRDSSIRARE------WTAVLLGERMR
CIMC----TISPSEVAETWHRI----FTGPVRMWIK----TCME----------------
----MTWTHSCRTTGLFPTETSQVLTMAPAGMVLYSLRRIL--------SVWTSSWRKPS
STEAPK-----ERPLVGAPR----------TMTMRRNAGRSETLSLSNFRLKSFFPYFFF
CN
>gi|122889577|emb|CAM13849.1|	Mus musculus
------------------------------------------------------------
---SVKKTWAEIRQQRWSWAGALHHSSPGRKTNRSLQLSAWESSIVDRLMTPTLSFLARS
R---------SAVTLPRNGRDQGRGSGPGRRPTRARAGASLAPGPHPDRTHPSAAVPVCP
RSASASPLTPCSAP-RSAHRCTPSG--ERPERRKPGAGGSPALARRRLEATPV-QKKEKK
DKERENEK--EKSALARERNLKKRQSLPASIRPR------LSTGSELSPKSKARPSSPST
TW-HRPASPCPSPGPGHALPPKPPSPRGTTASPKGRVRRKEEAKESPS-PSGPED---KN
HRKSRAAEEKEPAAPASPAPSPVP--S-PTPAQPQKEQSSTQIPAETAV------PAVPA
APTAPPTAAPSVTPSK----PM--AGTTDREEATRL----LAEKRRQAREQREREEQERK
LQAERDKRMREEQLAREAEARAEREAEARRREEQEAREK--------------------A
QAEQ-----------EEQERLQKQKEE-AEARSREEAERQRQEREKH--FQKEEQERQER
RKRLEEIMKRTRKSEAAETKKQDAKE-----TAANNS----GPDPVKAVETRPSGLQK--
DSMQKEELAPQEPQWSLPSKEM----PGSLVNGLQP----LPA-----------------
------HQENGFSPKGTAGDKS--LGRTAEGLLPF--------------AEAEAFLKKAV
VQP----------PQVTEVL----------------------------------------
--
>gi|121718886|ref|XP_001276225.	Aspergillus clavatus
------------------------------------------------------------
--------------------------MASIAEGLFKSLPKPKYTGEEE-EVPQHAQPRGP
RI-VGADQIDQSQIVLRKTGPPPYGNRTGWRP---RAAEDFGDG----GAFPEILVAQYP
LDMGRKGT-SSTSN-ALAVQVDAEGKVKYDAIARRGHSDNRIVHASFKDLIPL--RQRVD
MGEISLDR--PSEEEVEAQMEKTKNALASLVEGA------VAAQKPKNVRGGRRAEPT-F
VR-YTPANQ-MGDTSR----------------KNDRIMKIVERQQDPMEP--PKF---K-
HKKI-------PRGPPSPPPPIMH--S-PPRKLTAEDQEAWKIPPPVSN------WKNPK
GYTVPLDKRLAAD-GR----GL--QDVSINDKFAQFAEA-LFTADRHAREEVRLRAQMQQ
KLAEKEKAQKEEHLRALAQKAREERATSSRRDSRARSRSLSRSPSAYSSRSATPS----G
DEDA----------ARERERLRRERRQ-DAERQLRQSRMGTERRIQM--MAREQNRDISE
KVALGLAKPT--QASESMWDSRLFNQ-----TSGMHSGF--NED---NPYDKPLFAAQ--
DAIN----SIYRPR-AQVDVDDEEG-ADGEMSKIQK----TSR-----------------
------FEVLGKAKEGFRGAA---EAEAREGPVQFEK-------DTTDPFGIDSMIADVT
GGAGQ------KRYGIQEAE----------RDDRGSKRARVDDD----------------
--
