>gi|4507161|ref|NP_003099.1|	Homo sapiens
-------------------------------------------MVQQAESLEAE-SNLPR
EALDTE------------------------------------------------------
---------------------------------EGEFMACSPVALDE-------------
----SDPDW-----------C---KT----ASGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLKDSEKIPFIRE---AERLRLKHMADY
PDYKYRPRKKPKMDPSAKPSASQSPEKSAA------GGGGGSAGGGAGGAKTSKGSSKKC
GKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYV--------LGSLRVSGSGGGGAGKTVKC
VF---LDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLR-RYNV-AK
VPAS---PTLS----SSAESPEGASLYDEVRAGATSGAGGGSR-----------LYYSFK
NITKQHP-------PPLAQPALSPASSRS--------VSTSSSSSSGSSSG-SSGEDADD
LMFDLSLNFSQSAHSASEQQLGGGAAAG--------NLSLSLVDKDL----DSFSEGSL-
-GSHFEFP-------DYCTP-----ELSEMIAG---------------------------
------------DWLEANFSDLVFTY--
>gi|154147639|ref|NP_001093691.	Xenopus tropicalis
-------------------------------------------MSDDQSLSEVEMSPVGS
EDPSLTPDPLPPHAHSSPDDDEETKVKKEQDSE---------------------------
---------------------------------DERFPVCIREAVSQ-------------
--VLSGYDWTLVPMPVRVNGG---SK----SKPHVKRPMNAFMVWA--------------
---QAARRKLADQYPHLHNAELSKT-LGKLWRLLNENDKRPFIEE---AERLRMQHKKDH
PDYKYQPRRRKNGKPNPGE-----------------GDGSSEAEGGAAS-----------
-IQAHYKNSHLDHRHGSPMSDGNSEHSAGQSH--------GPPTPP----------TTPK
-----TELQAGKSD-----------------GKRDGSRSLGEGGKP-------HIDF-GN
VDIG---EISHDV--MANMETFDVNEFDQYLPPNGHAGHPSHI-----------GGYTSS
YGLSGALAAGP---SAWALAKQHPQTDSK----AQVKTESSSTSHYTEQPS-TSQLTYTS
LGLPHYGSAFPSISRPQFDYAD--------------HQPSSSYYSHSSQASSLYSAFSY-
-MGPPQRP-------LYTAISDSPSVAQSHSPT---------------------------
------------HWEQPVYTTLSRP---
>gi|156544646|ref|XP_001604913.	Nasonia vitripennis
------------------------------------------MLPEKRRETERE------
------------------------------------------------------------
-----------------------------------RFSVCISAAVAK-------------
--VLQGYDWTLVPVASKGSN----DK----RVAHVKRPMNAFMVWA--------------
---QAARKRLADQYPQLHNAELSKT-LGSLWRQLSESDKKPFIEE---ADRLRVIHKRTH
PDYKYQPRRKKQSGSSASSSSSSSSSTREVRNSSQQSNNVTFSVQSRAGCSQVGSLKQED
MSVCGDAMLGSPQTTSGSVGSSSPPTTPSQGL--------SPPTPP----------TTPR
GQHYVHQQHHGSVY-------QQLDLGPNHMQASPEMVQHQQPEHQ----HS-GVELPNY
LELPDNVPTLEDEQ-LSNLGTINLGIPLNLQECELEQYLPQQQ----------SLPALHQ
YGGQAINSPWLS--NRYDDDCVERLGKRHYSLEQTQAQQQQAPVA-------GDSNGWDD
LQSQQQQQQQQQQQRSREDMTRFH------------ELQPLSALPPVQYISQHHH-----
-HHHPQLG-------HQHAAAAAYAQYRHFVPSID-------------------------
------------SWPANYSS--------
>gi|126303246|ref|XP_001372169.	Monodelphis domestica
-------------------------------------------MVQQADSLESE-VNLPR
EAMDTE------------------------------------------------------
---------------------------------EGEFMACSPVALDE-------------
----SDPDW-----------C---KT----ASGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLKDSEKIPFIRE---AERLRLKHMADY
PDYKYRPRKKPKMDPSSKPNASQSPEKSANGGNG--GGGSGSGGGGGGNSKNSKSSSKKC
SKLKTSSSSSSTSSSSTSCSKPVAGKAAHHGDYTGEDLVFGTLKVNGSSGGGGCSKTVKC
-----VFMDDEEEDEEDEDDLQLRIKQEPEEEDEEHPGRQQQQQQQAQQLLR-RYSV-AK
VPAS---PTLS----SSAESTEGASLYEEVRAGATSAGGHGGG------GSASRLYYSFK
NITKQSA-------QQLQQPSLSPASSRS----VSTSSSSSSSS--------SSSEEADD
LMFDLSLNFSQNPHSATEQQLGGGSAAG--------NLSLSLVDKDL----DSFSEGSL-
-GSHFEFP-------DYCTP-----ELSEMIAG---------------------------
------------DWLEANFSDLVFTY--
>gi|157019404|gb|EDO64436.1|	Anopheles gambiae
-------------------------------------------MINHHTMASLGHPHYGF
ALSNGMDIPPAADFAPQPHHSPNSPTDHLGLKR---------------------------
---------------------------------GLTFPASSLASLQG-------------
---MGGGGGGGVNGQTS-------PG----QEGHIKRPMNAFMVWS--------------
---RLQRRQIAKDNPKMHNSEISKR-LGSEWKLLTEAQKRPFIDE---AKRLRATHMKEH
PDYKYRPRRKPKNPLASA------------------ANGLGALGAMQQS-----------
------------GKAGSLGSSYPFPQLPPYFA--------PA------------------
-----HPLQQLEQH----------------YPVPYFGSFDPLTLQK----LH-QSQQQSV
HQAG-----------HSPVGGLGGDSGKQ-------------------------------
--------------SAGQQLPPTSLSSFY----SNIYAGISASAA----AA-PLYAAHSN
SLYNTSSTSSASPGSSPSAS--------------------QSTLPDL-------------
-ENAMRRP-------VQVIY----------------------------------------
----------------------------
>gi|83588749|gb|ABB02374.2|	Salmo salar
-------------------------------------------MLKMTAEHDKSVSDPPC
SPAGTTSSMSQDDSDSDAPSSPTGSDGHGSLLAGIGKKLDGED-----------------
---------------------------------DDRFPACIRDAVSQ-------------
--VLKGYDWSLVPMPVRGNGS---LK----NKPHVKRPMNAFMVWA--------------
---QAARRKLADQYPHLHNAELSKT-LGKLWRLLSENEKRPFVEE---AERLRVQHKKDH
PDYKYQPRRRKSVKPGQS------------------DSDSGAELGNHMY-----------
--------------------KAEPGLLAGQPH--------GPPTPP----------TTPK
-----TDLHHGGKQ-----------------DMKHEGRRLLDSGRQ-------NIDF-SN
VDIS---ELSTDV--ISNMEAFDVHEFDQYLPLNGHASTAGAG--------------VDH
HGHHGLN-------PASGAGSYTSYSHAT-----------------------ANGAVWSR
KSAAMSASSSTSSEAVPQH-----------------------------------------
-RAHIKTE-------QLSPS----------------------------------------
------------HYSGDSH---------
>gi|109101920|ref|XP_001098988.	Macaca mulatta
-------------------------------------------MVQQAESLEAE-SNLPR
EALDTE------------------------------------------------------
---------------------------------EGEFMACSPVALDE-------------
----SDPDW-----------C---KT----ASGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLKDSEKIPFIRE---AERLRLKHMADY
PDYKYRPRKKPKMDPSAKPSASQSPEKSAA------GGGGGSASGGAGGAKTSKGSSKKC
GKLKAPAAAGAKAGAGKAAQAGDYGGAGDDYV--------LGSLRVSGAGGGGAGKTVKC
VF---LDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLR-RYNV-AK
VPAS---PTLS----SSAESPEGASLYDEVRAGATSGAGGGSR-----------LYYSFK
NITKQHP-------PPLAQPALSPGSSRS--------VSTSSSSSSGSSSG-SSGEDADD
LMFDLSLNFSQSAHSASEQQLGGGAAAG--------NLSLSLVDKDL----DSFSEGSL-
-GSHFEFP-------DYCTP-----ELSEMIAG---------------------------
------------DWLEANFSDLVFTY--
>gi|37719628|gb|AAR01926.1|	Arapaima gigas
-------------------------------------------MVQHTEQSETE-GSTSR
ETTDTE------------------------------------------------------
---------------------------------ENDMVAGSPVSVKP-------------
-------DW-----------C---KT----ATGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLKDSEKIPFIRE---AERLRLKHMADY
PDYKYRPKKKPKLDSSSKAA----------------VPSPEKSGSKTIK-----------
--TASKKCTKLKSTKVVPRPPADFKYDYGFSN--------LKVEKTVK------------
-----RELTDDEDD------------EEDYEDDMPVRIKQEEDEEQ----IM-PYNV-AK
VPAS---PTL-----SSSAESEGASMYEE-------VRNSAST----------RLFYNFK
NITKQGTSC-----TSVASPASSSRSVST--------------------SS-SAAEDADD
LLVDFSLNFASNAPGSELGNSSAG------------NLSLSFVDKDL----DSFSEGSL-
-GSHFEFP-------DYCTP-----ELSEMIAG---------------------------
------------DWLEANFSDLVF----
>gi|115394120|gb|ABI97016.1|	Ambystoma mexicanum
-------------------------------------------MADEQSLSEVEMSPTGS
EEEQCLSPGTSTASDGLRPGSPSDNDMAKVKKELDSETE---------------------
---------------------------------DEKFPICIREAVSQ-------------
--VLSGYDWTLVPMPVRVNGS---SK----SKPHVKRPMNAFMVWA--------------
---QAARRKLADQYPHLHNAELSKT-LGKLWRLLNENDKRPFIEE---AERLRMQHKKDH
PDYKYQPRRRKNGKATTGEGEV--------------PGEGDTVQGHYKN-----------
-----THLDLRRAGDRSPMSDGASEHGAGQSH--------GPPTPP----------TTPK
-----TELQNGKDP-------------------KRDGRPLGESSKP-------PIDF-GN
VDIG---EISHDV--MSNMEPFDVNEFDQYLPPNGHGGHASHV-----AGSYTGGYGLGS
ALAAAASSGSH---SAWISKPHGAASLAE--SKAQVKTESSGAGHYPEQSS-ASQITYAS
LGLPHYGSAFPAIPRPQFDYSD--------------HQPSGSYYSHGGQTSGLYSAFSY-
-MGPSQRP-------LYTALTESSSVAQSHSPT---------------------------
------------HWEQPVYTTLSRP---
>gi|110763018|ref|XP_001122993.	Apis mellifera
----------------------------------------MNDIMGEAGSGSISSSATPS
VANSANGSTAINGNTNIDNGSSNGSSNNGK------------------------------
---------------------------------AGNMNGGAVAANGG------ERISAAV
TKVLQGYDWTLVPVATKGSG----DK----RAAHVKRPMNAFMVWA--------------
---QAARRILADQYPQLHNAELSKT-LGKLWRLLSDNDKKPFIEE---ADRLRVIHKREH
PDYKYQPRRRKQNGPSGR------------------EGSPSRSQSNVTF-----NVSRSL
KQEDASPRPVQGPNSPQSGVSSSPPTTPNQGL--------SPPTPP----------TTPR
GQHYANQGNQPQPSATMYHHHQELGIGSSTEPSSQHQHQHQHQHQH----QP-GVDF-RY
IEVG---DGLP----IEEGQLNGLGSL---------AGVGLNL-----------------
--------------PLNLQECEVESNELDQYLRPQVPPPVHVPAPTTTTTA-SSSSPWIF
NRYDEEMERPSKRHCSEPQPIGETSWEDRAQADIVRYHELQPPLPPMQYISSSHNSHYSH
TGTQMSHP-------HVSTS---YAQYQRYVPGIE-------------------------
------------TWPHYM----------
>gi|2826914|dbj|BAA24575.1|	Oncorhynchus mykiss
-------------------------------------------MVQQTEHSETE-SSREA
TDTEES------------------------------------------------------
-----------------------------------ELMACSPVPLKS-------------
----VKADW-----------C---KT----ATGHIKRPMNAFMVWS--------------
---KVERRKIMEQSPDMHNAEISKR-LGKRWKLLKDSEKIPFIRE---AERLRLQHMADY
PDYKYRPKKKPKLDSSTKPA----------------AQSPEKTNIKPVK-----------
-----APGKKFAKLKTMKAVTTRPSHDPRYDY--------VFTSFT----------TSKS
-----VKMEYSDED----------DDEEDYEEEVFSRIKMEEDEEP-----I-PYNI-AK
VPAS---PTL-----SSTAESEGASMYEESR-----NANAAPT----------RLFYNFK
NITKQNTIC-----PASLSPASSFRSVST--------------------SS-SSSEDADD
LLVDFSLNLASSAHGVELGTSNSG------------NLSLSLVDKDL----DSFSEGSL-
-SSHFEFP-------DYCTP-----ELSEMIAG---------------------------
------------DWLDANFSDLVFTY--
>gi|2522255|dbj|BAA22778.1|	Xenopus laevis
-------------------------------------------MVQRADMDSSQ-HTEPS
TDTEEG------------------------------------------------------
-----------------------------------EFMACSPVPLDE-------------
----SDPDW-----------C---KT----ATGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLNDSEKIPFIRE---AERLRLKHMADY
PDYKYRPRKKPKVDPSASSKPPALTQSPEKSPKSRSAGRKCPKLKPSHS-----------
----GSGSKSLSIKSEYSGGSDEYVFGSPKAS--------GKAAAA----------AVKC
-----VFMDEDEEE------EEEEEDDEEEEDELQIRIKQEEDDEP----LR-QYNV-AK
VPAS---PTLSS---SSAESVEGASMYEDIRNGT-------------------RLYYNFK
NITKQST-------IPQATITLAPRPAPT---------------------T-TSPAGSHE
LLFDLSLNFTQQNPQLPDPNSG--------------NVSLSLVDKDL----DSCSEGSL-
-GSHFDFP-------DYCTP-----ELSEMIAG---------------------------
------------DWLEANFSDLVFTY--
>gi|45360120|gb|AAS59169.1|	Heliocidaris erythrogramma
-------------------------------------------MMDSAM-----------
------------------------------------------------------------
------------------------------------------------------------
------------------------GK----TSDHVKRPMNAFMVWS--------------
---RGQRRKLAQENPKMHNSEISKR-LGAEWKLLSEDDKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKPKSLMKRDKYAFPIPCIP--------TTSPYPVTTSGAD-----------
-------IMNMTSAEKARTYLSSHQHHAAAAA--------AAASQY--------------
-----SVLEHAQKL---------ESPTSLIRDFPPHPALYPPPHMYPTSAAAVPGSAFGK
LPGG-----------SAAAAAAAAGLHS--------------------------------
--------------QPYMMPYPAWPGQD------------------------GVQRPVAY
ILVKPDMEPYGA------------------------------------------------
-THPAIRP----------------------------------------------------
------------TMPLPTRPTAATAL--
>gi|56118239|ref|NP_033264.2|	Mus musculus
-------------------------------------------MVQQTNNAENTEALLAG
ESSDSGAGLELGI-----------------------------------------------
---------------------------------ASSPTPGSTASTGG-------------
--KADDPSW-----------C---KT----PSGHIKRPMNAFMVWS--------------
---QIERRKIMEQSPDMHNAEISKR-LGKRWKLLKDSDKIPFIQE---AERLRLKHMADY
PDYKYRPRKKVKSGNAGAGSAATAKPGEKGDKV---AGSSGHAGSSHAG-----------
----GGAGGSSKPAPKKSCGPKVAGSSVGKPH--------AKLVPAGGSKAAASFSPEQA
-----ALLPLGEPT--AVYKVRTPSAATPAASSSPSSALATPAKHPADKKVK-RVYLFGS
LGAS---ASPVGGLGASADPSDPLGLYEDGGPGCSPDGRSLSG-----------------
-RSSAASSPAASRSPADHRGYASLRAASPAPSSAPSHASSSLSSSSSSSSG-SSSSDDEF
EDDLLDLNPSSNFESMSLGS----------------FSSSSALDRDL---DFNFEPGS--
-GSHFEFP-------DYCTP-----EVSEMISG---------------------------
------------DWLESSISNLVFTY--
>gi|37926475|gb|AAP59791.1|	Trachemys scripta
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---LKGYDWSLVPMPVRGNGS---LK----AKPHVKRPMNAFMVWA--------------
---QAARRKLADQYPHLHNAELSKT-LGKLWRLLSENEKRPFVEE---AERLRVQHKKDH
PDYKYQPRRRKSVKAGQSDSDS--------------GAELSHHAGSQIY-----------
---------KADTGLGGVGDSHHHSDHTGQTH--------GPPTPP----------TTPK
-----TDLHHGSKQ-----------------ELKHEGRRLVESGRQ-------NIDF-SN
VDIS---ELSSE---VINMKTFDVRELDQYLPLNGHSAMPAGHGQNSSAGSYGPSYSHSA
NGTSGAAQAWTHKSPASVSPTLNETSQQR----PHIKTEQLSPSHYSDQSH-GSPTHSDY
GSYSAQACATTASTATAAA-----------------SFSSSQCDYTDLQSSNYYNPYSGY
PSSIYQYPYFHSSRRPYATP---------ILNGL--------------------------
------------SIPPAHSPTAN-----
>gi|27544772|dbj|BAC55017.1|	Halocynthia roretzi
----------------------------------------MQTDLKPIYSTSSQISPINS
QMHHMSG-----------------------------------------------------
---------------------------------IQQQVVGSVSAGSK-------------
------------------------SS----QEQRVKRPMNAFMVWS--------------
---RGQRRKMAQENPKMHNSEISKR-LGAEWKLLSEGDKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKTKMMKKDKY-----------------GSTILPSSTSSAV-----------
---------ATSIGRSPLPNSLDYQHLNGYGP--------YSTMIP--------------
-----------------------------QDPYSTQGYGVPGNQSAVGHLTQ-RYDMPMY
YPSYTAAPTIPT---MGNPGVSHLGGYHGPPTSYSVGPPTLPG-----------TPPYSN
VLHQPHV-------PTVKSPDTSPGGIGH----------QTPSCH----SG-SSPGQTPI
AGQPQCPPQAQAGQIQSMISM---------------YLPHSEHAGVTPVPSSSPAMDNS-
-RLASMQPA------HYSIP----LTSGVHIPH---------------------------
------------MHTMSNM---------
>gi|58223366|gb|AAW69293.1|	Carassius auratus
-----------------------------------------MNLLDRYLKMTQGVSVAPS
PSLSEDSAGSPCSSSGSGSDTETARAGIRRTELWDE------------------------
---------------------------------DEKFPVCIREAVSQ-------------
--VLKGYDWPLVPMPVRVNGS---TK----NKPHVKRPMNAFMVWA--------------
---QAARRKLADQYPHLHNAELSKT-LGKLWRLLNEGEKRPFVEE---AERLRVQHKKDH
PDYKYRPRRRNSVKSGLIETE---------------EGEQTQISTKAVF-----------
-----RALQQAEPTDSSKGEVHSPEDHSRHSQ--------DPPTTP----------TTPN
-----TERRVPSKE-----------------ELKRERGSHGERPPQ-----H-NIDF-GV
VDIG---ELSSDV--ISDIEAFDVKEFDQYLPPDGNPGAAGAK-----------------
--------------SAYSGHRSASARVHR-----PLASSSMAKAAQKHQQH-SPSSPGQQ
SAGHRRQQPAKEQPGSILQR----------------AERLLHTEYSLQQHSANCTSYP--
-PSHKSRL-------LFTPP---TEGVTPLVQ----------------------------
------------AWATFFFYTQLSRP--
>gi|32307765|gb|AAP79279.1|	Saccoglossus kowalevskii
-------------------------------------------MMEQTDLKQVS-MMGSG
QICSS-------------------------------------------------------
---------------------------------NPTTPTSSSANKML-------------
------------------------------GPDRVKRPMNAFMVWS--------------
---RGQRRKMAQENPKMHNSEISKR-LGAEWKLLSEAEKRPFIDE---AKRLRAVHMKEH
PDYKYRPRRKTKTLMKKDKYGL--------------PGMISPGGGAPVQ-----------
-----RAVDGMQYPLNGYMNGGYPMMQPDQLS--------AHTYQP--------------
-----HSLASAQSQ-----------------MAQANGGLHP------------RYDMPSQ
IYTP-----------MCTAGSYVN------------------------------------
--------------PPTSYTMTAPYTTQH------NQMHQSPAAVGISKSE-PMVSAATA
AAVAANRGRSCPGDLREMISM---------------YLPGDANDPNARQHSNAMVAHQ--
-EQYSQNP------------------SGVGVNGVS-------------------------
------------HYDHELK---------
>gi|110294132|gb|ABG66527.1|	Branchiostoma floridae
-------------------------------------------MMETAVHPAQP-SQPPS
ASSPTE------------------------------------------------------
------------------------------------LKPPTSGAVSP-------------
-----------------GNKA---AN----DSSRVKRPMNAFMVWS--------------
---RGQRRKMAQENPKMHNSEISKR-LGAEWKLLTEAEKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKTKTLMKKDKYSL--------------PGGLIAANGAPVQ-----------
--------------RTIATGMDQYAHMNGYMS--------NNAYT---------------
-----HMMHQDQLH----------AYPHPGISPAQTASQMASNASL----PP-RYDMSGQ
IPPY---PMAT----TNSYSSYTSSSYTT-------------------------------
--------------NPYSHHYTTPQTMSS----------QMPPGFTTVKTEAGPAAPTGT
PPADGRGRNPCPGDLREMISM---------------YLPGDANDPNAQS-----------
-RLHSMQG-------HYQNS--------VGVNG---------------------------
------------TVPLSHM---------
>gi|91083765|ref|XP_971967.1|	Tribolium castaneum
-------------------------------------------MCEGGFSAAEGLSRMAS
LGGA--------------------------------------------------------
---------------------------------ALGVPQGLQNPQAT-------------
------------------------KK----QEDHIKRPMNAFMVWS--------------
---RLQRRKIAQENPKMHNSEISKR-LGAEWKLLTEDEKRPFIDE---AKRLRAMHMKEH
PDYKYRPRRKPKTLRKEGYPYSIPYPSVPMDALR--AGMAASSMGQSMA-----------
SYYNPSAAYGSLSAASMAAAAAAAQQSAAAMS--------AGLTAP--------------
-----AQVVSSMDA--MKYSMEADKYRSPYIPPSTLAMSMYSDPKYMDSSSK-SYLERGY
LDST---SALT----KAYFESSKMYMDSKYNPDPSRSYPLDIG-----------------
--------------KMYSDASAPQQVPGNLGSPRSPDSPDVKPNPERQDGASSSSSTTTS
SAGASPGALPGYYPSSGMQQ----------------GATVPGLLPMAQYASQYPTQTP--
-GGEFRRP--------LTVRSCEYLSKYSSRKG---------------------------
------------NHRRNCM---------
>gi|34875531|ref|XP_344595.1|	Rattus norvegicus
-------------------------------------------MVQQTNNAENTEALLAG
ESSDSGAGLELGI-----------------------------------------------
---------------------------------ASSPTPGSTASTGG-------------
--KADDPSW-----------C---KT----PSGHIKRPMNAFMVWS--------------
---QIERRKIMEQSPDMHNAEISKR-LGKRWKLLKDSDKIPFIQE---AERLRLKHMADY
PDYKYRPRKKVKSGNTGAGSAATAKPGEKGDKV---AGGSGHAGSGHAG-----------
----GGAGGSSKPAPKKSCGPKVAGSSVGKPH--------AKFVPAGGGKAAASFSPEQA
-----ALLPLGEPA--AVYKVRTPSAATPAASSSPSSALATPAKHPADKKVK-RVYLFGS
LGAS---ASPVGGLGASADPSDPLGLYEDGGPGCSPDGRSLSG-----------------
-RSSAASSPAASRSPADHRGYASLRAASPAPSSAPSHASSSLSSSSSSSSG-SSSSDDEF
EDDLLDLNPSSNFESMSLGS----------------FSSSSALDRDL---DFNFEPGS--
-GSHFEFP-------DYCTP-----EVSEMISG---------------------------
------------DWLESSISNLVFTY--
>gi|87133392|gb|ABD24303.1|	Branchiostoma belcheri
--------------------------------------MVPQNGNGSTGSTGTGVRVLPG
WEHAAPAGSGPAGGKPTITNMESASDSDYDSDTSSSSVDSNVS-----------------
---------------------------------TNSNVTTSSDGTSA-------------
----SNDSGALVKSPSAGSGATSPKSKKSCRDGHIKRPMNAFMVWS--------------
---QIERRKISEQAPDMHNAEISKR-LGRRWKLLSAEERIPFIRE---AERLKVVHMETY
PDYKYRPRKKVKKAEEKPSSGS--------------KNGKDKKKSKSKS-----------
-----KKSSGSKSSGGGAREQVRHSGLAQTTH-----REKALKVPK--------------
-----LKLTIDRRF----------------RESIAASKAVELPPS--------QHTPPAK
VPSS---PTA-----RTPDRAEPVSFYDDFEPIQ--------------------------
--------------RAVQAKPAAPVETQP-----------------------EVQSETDA
GLLQTCMDMDMNMDFMDL------------------DIPGSSPFLDLNTV----------
-ASHFDFQ-------DYSTP-----EVSELIQG---------------------------
------------DWLEASLASLL-----
>gi|148763342|gb|ABR10399.1|	Epinephelus coioides
-------------------------------------------MVQHTEHGGPRIHSGSR
EAADTE------------------------------------------------------
---------------------------------DSELLAASVCGPVP-------------
----QKADW-----------C---KT----ASGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLKDTEKIPFIRE---AERLRLKHMADY
PDYKYRPKKKPKTDGCAFPTGKLA------------AQSPEKTSVRPVY------KKNLS
KLKPSKPVTGSGRAISLLPQHQHPDHRYRYVL--------TTSFKPNKFGK---------
-----RDFTDDEEE-----EDDDDEDDDEGDSEEERGFKLEEEDEP-----S-RYSL---
-GLS-----------SAAAEPEGTGMYESSG----------------------RLFYSFK
NITRQGTGTGTGSYPASLSPASSSRSSSS----CCGEDLDDLPAE-----G-TDFTLSLL
AGLHASSEPWSSSSSSAPG-----------------NLGLSLVDLDL---DSCGSERTL-
-GSHFDFP-------DHCTP-----ELSEMIAG---------------------------
------------NWLEVNFSDLVFTY--
>gi|49204505|dbj|BAD24665.1|	Cynops pyrrhogaster
-------------------------------------------MYSMMMETDLH-SPGAQ
PPANTG------------------------------------------------------
---------------------------------QSGVGGGGGGAGGA-------------
------------------------KA----NQDRVKRPMNAFMVWS--------------
---RGQRRKMAQENPKMHNSEISKR-LGAEWKVMSEGEKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKTKTLLKKDKYSL--------------AGGLLSAGGGPGG--------MGV
GLSPGGVGQRLESPGGGGAGGGGYAHMNGWAN--------GG-YPGSVAAAAAAAMMQE-
-----AQLAYSQQQ-----------QQHHHPHHPHHAHHHPHQPQP----MH-RYDM-SA
LQYS---PLGS----QGYMSASPSGYALSYSGGQGGGQPPQGGS----------------
--------------ATSASSASGALGALG----SLVKSEP------------SVSPPVSG
SAVHPSARAPCPGDLREMISM---------------YLPAGEAA------EAAAAGGRL-
-LHGLSQP-------QQQAH---YHHHQSAVNG---------------------------
------------TVPLTHI---------
>gi|76631951|ref|XP_875555.1|	Bos taurus
-------------------------------------------MYSMMMETDLH-SPGGA
QAPT--------------------------------------------------------
---------------------------------NLSGPAGAGGGGGG-------------
----------------GGGGS---KA----NQDRVKRPMNAFMVWS--------------
---RGQRRKMAQENPKMHNSEISKR-LGAEWKVMSEAEKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKTKTLLKKDKYSL--------------AGGLLAAGAGGGA---------AV
AVGVGAAAVGQRLESPGGAAGGGYAHVNGWAN---------GAYPGSVAAAAAAAAMMQE
-----AQLAYGQHP----GAGGAHPHAHPAHPHAHHPHAHPHNPQP----MH-RYDM-GA
LQYS---PISN----SQGYMSASPSGY-------GGLPYGAAG-----------------
--------------GAHQNSAVAAAAAAA----------AASSGALGALGSLVKSEPSGS
PPAAAHSRAPCPGDLREMISM---------------YLPAGEGGDPAAAQS---------
-RLHSLPP-------HYQGA-------GAGANG---------------------------
------------TVPLTHI---------
>gi|125979029|ref|XP_001353547.	Drosophila pseudoobscura
--------------------MATLSSHPNYGFHLGAGGGQGLELPSPSDYAHQG-QLQLS
PGMDMDIKRVLHYSQSLAAMGGSPNGNGLPSGPGMGHHHHMTPH----------------
---------------------HMHSAVSAQQTLSPNSSIGSAGSLGSQSSLGSSGMGNGS
SIGSSGHANHQSSGMHSLATS---PG----QEGHIKRPMNAFMVWS--------------
---RLQRRQIAKDNPKMHNSEISKR-LGAEWKLLAESEKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKPKNPMTAGP-----------------QGGLQMQANGMGQ-----------
--------QKLGGGPGAGAGGYNPFHQLPPYF--------APS-----------------
-----HHLDQP-------------------YPVPYFGGFDPLALSK----LH-QSQAAAA
AAAN-----------NQGHKVLESQ-----------------------------------
--------------QAPPQLPPTSLSSFY----SGIYSGMSAPSL----YA-AHSANAAA
AGLYTSSSTSSPGSSPGTIT-------------------------------PNGMDGSM-
-DSALRRP-------VPVLY----------------------------------------
----------------------------
>gi|45685155|gb|AAS75331.1|	Gallus gallus
-------------------------------------------MVQQTGTAENTEALPAA
ETSAAGVGLELGI-----------------------------------------------
---------------------------------ASSPTPGSTASTGG-------------
--KADDPSW-----------C---KT----PSGHIKRPMNALMVWS--------------
---QIERRKIMEQSPDMHNAEISKR-LGKRWKLLKDSDKIPFIRE---AERLRLKHMADY
PDYKYRPRKKVKSGNSSAKPADKADRAAGGG-----GGGAGPGGGSAGG-----------
--GPGGGTAKPAPKKGGGGGGPRPSPAGPKPH--------GKAAAGGKASPPGTGETTAA
-----PPPPPPPEHQALYKPRGAPAAPGKAAAERKLKRVYIFGGGGPAAAAA-SGSPGGA
VPGS---PTLT----SAAEAGDPLSLYEEAGGAARPDGDCPSP-----------PGARSP
AEHRGYAG------PRAASPAPSTARSSS----ASSHSSSASSAG-------SSSSDDEF
EDDLLDLNPSPGFESMSLG-----------------GFGSSALDRDL---DFNLEPGS--
-GSHFEFP-------DYCTP-----EVSEMISG---------------------------
------------DWLESSISNLVFTY--
>gi|21357779|ref|NP_648694.1|	Drosophila melanogaster
-------------------------------------MTSISALLHRSHSHSNGYTSSGS
SNHSHSSSLSPQLPGINLGLGMVGGLGMGMSVGVGSGSGNTTPP----------------
---------------------PMPPA-------DLAVPPAAPTPVAP---------KMHQ
HTHHHGNSHHNAPTSHSNSNTGSHHN----SHDHIKRPMNAFMVWS--------------
---RGQRRKMAQDNPKMHNSEISKR-LGAEWKLLTEGQKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKPKTLNKSPVPG---------------GGGGGGGGGANGG-----------
----VNAGGAGNSGPSGPGSVGSPKDMQPQLS---------PLGQS--------------
-----LPHLHGHPH------------QSPYQSHPHHPHPHPHHVQLAAATLSAKYGFGSP
LELS--LPRLPNA--FPGLAHYPLD-----------------------------------
--------------PTLALDLQARLQAMY--------------------AG-SIYHPWRY
LPLISPETPPSPPSSSGT------------------GISSYGCVKSEKSSPNAVV-----
-ASAASPP----------------------------------------------------
------------NII-------------
>gi|73989544|ref|XP_849239.1|	Canis familiaris
-------------------------------------------MYSMMMETDLS-SSGGA
QAP---------------------------------------------------------
-----------------------------------TNPLGPAGAGGG-------------
--GGGGGGGGGGGGGGGGGVA---KA----SQDRVKRPMNAFMVWS--------------
---RGQRRKMAQENPKMHNSEISKR-LGAEWKVMSEAEKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKTKTLLKKDKYSL--------------AGGLLAAGAGGGG--AAVAMGVGV
GVGVGAAAVGQRLESPGGAAGGGYAHVNGWAN---------GAYPGSVAAAAAAAAMMQE
-----AQLAYGQHPGAGGAHPHPHPHAHPAHPHPHHPHAHPHNPQP----MH-RYDM-GA
LQYS---PISN----SQGYMSASPSGYGGLPYGAAAAAAAAAG-----------------
--------------GAHQNSAVAAAAAAA----------AASSGALGALGSLVKSEPSGS
PPAPAHSRAPCPGDLREMISM---------------YLPGGETGDPAAAAAAAAQS----
-RLHSLPQ-------HYQGA-------GAGVNG---------------------------
------------TVPLTHI---------
>gi|80973855|gb|ABB53636.1|	Petromyzon marinus
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------SQ-------------
--VLKGYDWTLVPMPVRVNGS---SK----SKPHVKRPMNAFMVWA--------------
---QATRRKLADQYPHLHNAELSKT-LGKLWRLLSENEKRPFVEE---AERLRVQHKKDH
PDYKYQPRRRKSGKNGQSESDS--------------SGEQTHITTNAIY-----------
---------KALQADSPSADVHSPGEHSGQSQ--------GPPTPP----------TTPK
-----TDVQSNKLD------------------IKREGRPLQEGGRQ-------QIDF-SN
VDIR---ELSREV--ISNMESFDVNEFDQYLPPNGHPGHGQSV-AASYGGTGYSINGHAW
LSKQQQQQQQQQQQQHTLSSPPPPPAISSPEQRAHVKTEQLSPSHYSDQQQ-QQQQPQQQ
QQQHSPQQQQQQQQQPQQAQQAQQQVQQQQLGG---YSPFSIQHYGAAVVPAISRSQYSY
ADHHHHHH-------HHQSSAAAAAYYSGHSAGQTAGLYSGFSYMGPSQRPSYTPIADAT
GVPSIPQPHSPPSWEQPVYTTLTR----
>gi|156723185|dbj|BAF76752.1|	Rana rugosa
-------------------------------------------MYSMLDTDIKSPVQQAS
AQS---------------------------------------------------------
---------------------------------GGAVTPGAKGNAAN-------------
-------------------------Q----DQDRVKRPMNAFMVWS--------------
---RGQRRKMAQENPKMHNSEISKR-LGADWKLLSDSEKRPFIDE---AKRLRAVHMKEY
PDYKYRPRRKTKTLLKKDKYSL--------------PGNLLAPGVSPVS-----------
------------STVGVGQRIDTYAHMNGWTN--------GA------------------
-----YSLMQDQLG------------------YSQHPGMNSPQIQQ----MH-RYDM-SS
LQYN---PMMS----SAQTYMNAASTYSMS------------------------------
--------------PAYNQQTSTVMSLGS--MGSVVKSEPSSPPP---------------
-AITSHTQRACLGDLRDMISM---------------YLPPGGDASDPSSLQNS-------
-RLHSVHQ-------HYQSA-------GTAVNG---------------------------
------------TVPLTHI---------
>gi|3915056|sp|Q91731|SOX11_XEN	Xenopus laevis
-------------------------------------------MVQRADMDSSQ-HTEPS
TDTE--------------------------------------------------------
---------------------------------EGEFMACSPVSLDE-------------
----SDPDW-----------C---KT----ATGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLNDSEKIPFIEE---AERLRLKHMADY
PDYKYRPRKKPKVDPSASSKPPALTQSPEKSPKSRSAGRKCPKLKPSHS-----------
----GSGSKSLSIKSEYSGGSDEYVFGSPKAS--------GKAAAA----------AVKC
-----VFMDEDEEE------EEEEEDDEEEEDELQIRIKQEEDDEP----LR-QYNV-AK
VPAS---PTLSS---SSAESVEGASMYED-------IRNGTRL------------YYNFK
NITKQST-------IPQATITLAPRPAPT---------------------T-TSPAASHE
LLFDLSLNFTQQNPQLPDPNSG--------------NVSLSLVDKDL----DSCSEGSL-
-GSHFDFP-------DYCTP-----ELSEMIAG---------------------------
------------DWLEANFSDLVFTY--
>gi|18859409|ref|NP_571718.1|	Danio rerio
-------------------------------------MNLLDPYLKMTDEQEKCLSDAPS
PSMSEDSAGSPCPSASGSDTENTRPAENSLLAADGTLGDFKKDE----------------
---------------------------------EDKFPVCIREAVSQ-------------
--VLKGYDWTLVPMPVRVNGS---SK----NKPHVKRPMNAFMVWA--------------
---QAARRKLADQYPHLHNAELSKT-LGKLWRLLNEVEKRPFVEE---AERLRVQHKKDH
PDYKYQPRRRKSVKNGQSESED--------------GSEQTHISPNAIF-----------
-----KALQQADSPASSMGEVHSPSEHSGQSQ--------GPPTPP----------TTPK
-----TDTQPGKAD------------------LKREARPLQENTGR----PL-SINF-QD
VDIG---ELS-----SDVIETFDVNEFDQYLPPNGHQNAPYAG----------GYAAWMT
KPQNGS--------PQSSQLTPLNPAEPDQPRTTHIKTEQLSPSHYNEQQGSPQHISYGS
FNVQHLQHYSTSFPSITRAQYDYSDSHQ--------GGASSYYTHAGGQSSGLYSTFSY-
-MSSSQRPMYTPIADSTGVP---SIPQSNHSPQ---------------------------
------------HWDQQPVYTQLSRP--
>gi|70571230|dbj|BAE06704.1|	Ciona intestinalis
-------------------------------------------MLTVDHNPNWMQIPYPT
SGVPVIPSNAHLPPPAPIAGSTPTSGSQG-------------------------------
---------------------------------DVKPYIGENGHLGG------------S
MTHLSPPMMNHVQGSHNQNNNNSSANNKVPQEQRVKRPMNAFMVWS--------------
---RGQRRKMAQDNPKMHNSEISKR-LGAEWKTLSDSDKRPFIDE---AKRLRALHMKEH
PDYKYRPRRKTKAILKKEN-----------------KFGMGPGGIMGGG-----------
------AGPQMSASGQRSHMSAAPIDYSQYYQ----------------------------
-----HSMMAGSQD-----------PMAYGAPSPHAYPAMANSGTA----AN-RYDM--Y
YPSY---STPTTLPSMSSLTSQHNSYAQSAYSVGGSPAYSVAQ-----------------
--------------AHTPTNSLHSMAGSHHGSSGVHSPANTSPGASSVTSA-AASSGGSP
LHQQLQSMLPLHSHQLPISQM---------------YLPISEQQPASATTPTDPSHSPGL
SRLNSIGP-------GTHYP---ISTSMGQLPM---------------------------
------------HMPAHM----------
>gi|83657493|gb|ABC40395.1|	Amia calva
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------PMNAFMVWS--------------
---KIERRKIMEQSPXMHNAEISKR-LGKRWKMLKDGEKIPFIRE---AERLRLKHMADY
PDYKYRPKKKPKLDSASKPS----------------APSPDKHGVKVSK-----------
--TPGKKCPKLKSGKTGSKSSPEYGDDYAFPS--------LKATKPTR------------
-----SVLTDEDDD-------------EDYEDDLQMRLKQEDEEQQ----LR-PYGV-AK
VPAS---PTL-----SSSAESEGASMYEEVRTAAAAAAAAAPN---------SRLFYNFK
NITKQSTSY-----PASVSPASSRSVSTS---------------------S-SSSEDADD
LLFDFSLNFAPNAAGSDLGHPSSG------------NLSLSLVDKDL----DSFSEGSL-
-GSHFEFP-------DYCTP-----ELSEMIAG---------------------------
----------------------------
>gi|72164888|ref|XP_798084.1|	Strongylocentrotus purpuratus
-------------------------------------------MVPQNLTSNGLITMQSQ
QIPNGHGSPGSTG-----------------------------------------------
---------------------------------SSEELRQSTLDIAE-------------
--DICQTNW---------------KG----NNGHIKRPMNAFMVWS--------------
---QIERRRIMETTPDMHNAEISKR-LGRRWKTLDEVAKSPYVEE---AERLRLLHMAQY
PDYKYRPRKKSKPTTKPE------------------AAKTTSSKPKANK-----------
----PKSSSKLTKMNGIVIDQMHPHQIVQSGR--------IEKIPK--------------
-----LKLTIDKKF----------------RENMKASKIVELVPS--------QLTPPAK
VPAS---PTG-----SNTDPCNEQSLYEDYANIQHTYEM---------------------
--------------QRYEFGVPSGATSTTCSSPASSDVSQQSSMSTNSSVS-SMSTGSSY
CAQQSIEDVVFPGGLTGSEFN---------------NFNFGSVPDDLSPLDSVGSN----
-GSHFEFP-------DYTTP-----EVSELIDS---------------------------
------------DWLLSSMISAYN----
>gi|37719650|gb|AAR01937.1|	Oreochromis niloticus
--------------------------------------------------SETD-GSMSR
EATDSE------------------------------------------------------
---------------------------------ESEFMACSPVAINP-------------
-------DW-----------C---KT----ATGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLKDSEKIPFIRE---AERLRLKHMADY
PDYKYRPKKKPKLDSSKSSAPS--------------PEKCGKIAKTPNK-----------
-------KSSKIKTKSGSKSTHGYAEDCVFPS--------LKVAKTVK------------
-----SELTDEDDD--------------DEYEEDYRMGIKPGEEER----LR-PYNV-AK
VPAS---PTL-----SSSAESEGTSMYEEVRNNN-------------------RLFYSIK
NITKQ---------STLHAASVSPASSRS----VSTSSSSSSISS-------SSGDDADD
LLFDFSLNFAPSAPGSELGNPNSG------------NLSLSLVDKDL----DSFSEGSL-
-GSHFEFP-------DYCTP----------------------------------------
------------ELSE------------
>gi|37719622|gb|AAR01923.1|	Acipenser baerii
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------T----ATGHIKRPMNAFMVWS--------------
---KIERRKIMEQSPDMHNAEISKR-LGKRWKMLKDNEKIPFIRE---AERLRLKHMADY
PDYKYRPKKKPKLDTSSKPS----------------MHSPEKTGSTKIA-----------
-KTPGKKCSKLKPSKPGAKSSHDYGEEYTFGN--------FKSNKAVK------------
-----SVLTDEDDE-------------DDEYDDDLQMRIKQEDEEQ----MR-PYNV-AK
VPAS---PTL-----SSSAESEGASMYED-------IRNAASN----------RLFYNFK
NITKQSTAH-----PASVSPASTRSVSTS---------------------S-SSSEEADD
LLFDFSLNFAPNSQVSELGNPNSG------------NLCLSLVDKDL----DSYSEGSL-
-GSHFEFP-------DYCTP-----ELSEMIAG---------------------------
------------DWLE------------
>gi|47229514|emb|CAF99502.1|	Tetraodon nigroviridis
-------------------------------------------MVQHMSQTESAHAHSPG
GDSTDTGDMDL-------------------------------------------------
---------------------------------EMDASPTPEFPSNG-------------
--ERSDLAW-----------C---KT----PTGHIKRPMNAFMVWS--------------
---QIERRKIMEQSPDMHNAEISKR-LGKRWKLLKDTDKIPFIRE---AERLRLKHMADY
PDYKYRPRKKVKSGSGASKQAE--------------RGEKSGERGAKAG-----------
-------VKRSPASKAVSKTHKQVGVKSAAGQ--------DCPSPAD-------------
-----HQTLFKSRS----------VSGARQIPEKRSGEARRGHMFGGASSLE-SGPLSVG
VPAS---PTLS----SSAESSDPLSLYEEQ------------------------------
--------------SPATSESSHTARLRY----TRASSPTPSASHSSSSVS-SSSSDEEF
EDERVDLNPSPGFESMSLGGM---------------GFSDAELDRDL---DWNFGECGA-
-GSHFDFP-------DYCTP-----EVSEMISG---------------------------
------------DWLESTISNLVFTY--
>gi|115344218|gb|ABI95135.1|	Lates calcarifer
-------------------------------------------MYNMMETEIKT-PLPQS
------------------------------------------------------------
---------------------------------NSGSAPGAKNNSAS-------------
------------------------------DQERVKRPMNAFMVWS--------------
---RGQRRKMAQENPKMHNSEISKR-LGADWKLLTDAEKRPFIDE---AKRLRAMHMKEH
PDYKYRPRRKTKTLLKKDKYSL--------------PGGLLPPGANAVN-----------
------------NSVSVGQRMDGYAHMNGWTN--------SA------------------
-----YSLMQDQLA------------------YPQHHSMNSPQIQQ----MH-RYEM-AG
LQYP---MMSSAQTYMNAASTYSMS-----------------------------------
--------------PAYTQQTTSAMGLSS--MASVCKTEPSSPPP---------------
-AITSHSQRACLGDLRDMISM---------------YLPPGGDSAEHSSLQSS-------
-RLHSVHP-------HYQTA-------GTGVNG---------------------------
------------NLPLTHI---------
>gi|157111610|ref|XP_001651645.	Aedes aegypti
-------------------------------------------MINHSMASLSH-PHYGF
SLGNHQMDMPPAADYAPQPNHSPGSVDVKP------------------------------
---------------------------------RLSFPPTSLAGFQT-------------
------------HTPTQSGSHQTSPG----QDGHIKRPMNAFMVWS--------------
---RLQRRQIAKDNPKMHNSEISKR-LGSEWKLLTEAQKRPFIDE---AKRLRASHMKEH
PDYKYRPRRKPKNPLANA------------------AGGLSLGMQQSAK-----------
---------------NALGSSYPFPQLPPYFA------------PT--------------
-----HHLQQLEQH----------------YPVPYFGGFD-------------PLTL-SK
LHQS-----------QQNMQSTSPTGLEA-------------------------------
--------------QKTQQMPPTSLSSFY----SNIYSGISAAAAAA-----PLYAAHSN
GLYNSSTSSASPGSSPST------------------SQQSTVLPSDI-------------
-ENSMRRP-------VQVIY----------------------------------------
----------------------------
