>gi|50304753|ref|XP_452332.1|	Kluyveromyces lactis
------------------------------------------------------------
------------------------MLARKRLAIIEAIRKVRTMSAP--------------
----------------------------------------KVVQPK-----WFKP----E
QQKPLPVLKLYNTLTRNKEEFVTHS----NSKCVTW---------------YSCG---PT
VYDASHM------------------GHA-------------------RNYVSIDINRRIL
QDYFGYDINFVQNVTDIDDKIIIRARQNFLFEEYVKRNDNKV----TEDTVEEVKISLFE
FVEKNLNQ---------KFSTVEEYE--SWFSGL--DLEKEKVENPKFSMYSTSVSNAIE
SLKSK------------GDNFFELAKDVLVPLLDKKFGSTLN--DPDIFRKLPAYWEQRY
DQ--DMAALNVLPPTVTTRVSEYVPEIVQFVETIISNGYAYATS-----DGSVYFDTAKF
DSSEGHEYAKCQPWNKGQL-----DLIQDGEGSLSDFSAK--NGKRSANDFALWKASKPG
EPEWPSPWGKG-RPGWHIECSVMASD-IHGSVIDIHTGGIDLAFPHHDNELAQSEACYDN
-----HQWINYFLHTGHLHIEGQ--KMSKSLKNFITIEEALNK--YSARQLRLAFASVQW
NNQLDFKDSLLNEVKSLESSFT-----------------------NFFKNIRALNNDYKH
SLGLGKI-VSKKLSNEEKALLNVLKSTQEKVHASFCDNLSTPQVLKHLNELLTKSNSYI-
--ANI-------SSELK-IEPLLAITRYISKILGVIG----FQLRS-DGLGWLD-DSSSD
SSP------DV-------------------------------SKEDIALPYVRCLSYFRD
EVR--QLAMNKA----------PSSQ---------FLQATDRLRDEELVALNVAVDDRQG
-----QASLVKFLTDKEKDEIMKINEEKLQKEAEKQSKKLEQL-----------------
-RLQEAKKQERLEKAKI-SPQDMFK----NDLYSEWDE-DGIPTKDKDGNEVTKSMNKKL
KKQWLAQKKLHEEFFQ-----------
>gi|6324082|ref|NP_014152.1|	Saccharomyces cerevisiae
------------------------------------------------------------
-----------------------------MNIFIKALRRYTIMSTP--------------
----------------------------------------KIVQPK-----WKVP----T
PQAKETVLKLYNSLTRSKVEFIPQS----GNRGVTW---------------YSCG---PT
VYDASHM------------------GHA-------------------RNYVSIDINRRII
QDYFGYDVQFVQNVTDIDDKIILRARQNYLFDNFVKENDTKF----NATVVDKVKTALFQ
YINKNFTIQGS------EIKTIEEFE--TWLSNA--DTETLKLENPKFPMHVTAVQNAIE
SITKGDSMD--------AEVAFEKVKDVTVPLLDKELGSTIS--NPEIFRQLPAYWEQKF
ND--DMLSLNVLPPTVTTRVSEYVPEIIDFVQKIIDNGYAYATS-----DGSVYFDTLKF
DKSPNHDYAKCQPWNKGQL-----DLINDGEGSLSNFAD---NGKKSNNDFALWKASKAG
EPEWESPWGKG-RPGWHIECSVMASD-ILGSNIDIHSGGIDLAFPHHDNELAQSEARFDN
-----QQWINYFLHTGHLHIEGQ--KMSKSLKNFITIQEALKK--FSPRQLRLAFASVQW
NNQLDFKESLIHEVKSFENSMN-----------------------NFFKTIRALKNDAAS
AGH-----ISKKFSPLEKELLADFVESESKVHSAFCDNLSTPVALKTLSELVTKSNTYI-
--TTA-------GAALK-IEPLIAICSYITKILRIIG----FPSRP-DNLGWAA-QAGSN
DGS------LG-------------------------------SLEDTVMPYVKCLSTFRD
DVR--SLAIKKA----------EPKE---------FLQLTDKIRNEDLLNLNVALDDRNG
-----QSALIKFLTNDEKLEIVKLNEEKHANELAKKQKKLEQQ-----------------
-KLREQKENERKQKAQI-KPQDMFK---DVTLYSAWDE-QGLPTKDKDGNDITKSMTKKL
KKQWEQQKKLHEEYFGEDK--------
>gi|26328991|dbj|BAC28234.1|	Mus musculus
------------------------------------------------------------
-----MAGSSAEQAADYRSILSISDEAARVQALDQHLSTRSYIQGYSLSQADVDVFRQLS
APPADSRLFHVARWFRHIEALLGGPQGRDEPCRLQAS-KGRRVQPQ-----WSPP----A
GTEP-CRLRLYNSLTRNKDVFIPQD----GKK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
RDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQYREQKPP------ATQLLKDVRDAMKP
FSVKLSETTDPD-----KRQMLERIQ----------NSVKLATEPLEQAVRSSLSGEEVD
SK---------------VQVLLEEAKDLLSDWLDSTGGSEVT--DNSIFSKLPKFWEEEF
HK--DKEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYAS------NGSVYFDTAKF
AASEKHSYGKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGT-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSSNTMESALQYEKFMN-----------------------EFFLNVKDILRAPVD
ITG-----QFEKWEAEEVELNKNFYGKKTAVHEALCDNIDTRTVMEEMRALVSQCNLYMA
ARKAE-------RRRPN-RALLENIAMYLTHMLKIFG----AIEEE-SPLGFPV----GG
PGT------NL-------------------------------NLESTVMPYLQVLSEFRE
GVR--KIAREKK-----------VLE---------VLQLSDALRDDILPELGVRFEDHEG
-----LPTVVKLVDR---DTLLKEKEGKKRAEGEKRRKKEEAA-----------------
-RKKQEQEAAKLAKMKI-PPSEMFLS--EVNKYSKFDE-NGLPTHDTEGKELSKGQAKKL
KKLFEAQEKLYKEYLQMLQNGSLQ---
>gi|50291223|ref|XP_448044.1|	Candida glabrata
------------------------------------------------------------
-------------------------------MVNWSVLKRTVMSAANS------------
----------------------------------------KVVQPK-----WINPAQCSE
RTQA-PVLKLYNSLTRSKEVFAPSS----GTKTVSW---------------YSCG---PT
VYDASHM------------------GHA-------------------RNYVSIDINRRLI
QNYFGYDIQFVQNVTDIDDKIIIRARHNYLFEEFVKQNDSETPLNESDEIVKKANDATIS
YINKNLADVLGS-----SQESVNTFL--VAAEKV--NHEEAKLKDPKFPMHMTSVQNAIS
ALSNVSKLP--------RRKFFDGVKDVLVPVLDKELGSTIN--DPEIFRKLPAYWEKQY
DS--DMAALNVIPPNVTTRVSEYVPEIVSFVEDIINNGYAYATN-----DGSVYFDTVRF
DQNEKHDYAKCQPWNKGKL-----DLINDGEGSLSNFDN---NGKKSANDFALWKGSKPG
EPAWDSPWGKG-RPGWHIECSVMASD-ILGSNIDIHSGGIDLAFPHHDNELAQSEAKFDN
-----KQWINYFLHTGHLHIEGQ--KMSKSLKNFITIQEALQK--YTPRQLRLAFASVPW
NNQLDFKESLIHEVKSFETSMN-----------------------NFFANVRAHYNDYKS
SLEDDSIIVSKKLTNLEKDLLEEFKKSQEKVHAAFCDNLSTGQALKTLSDLVTTTNTYI-
--TNS-------GKDLK-IEPVISICKYITKILDIVG----FPGRP-DGLGWVAQASSVS
SGSESANQISG-------------------------------SIEEIAMPYVKCLSTFRD
SVR--SMAIAKA----------QPQE---------FLKLTDTVRDNDLLNLNVSLDDRNG
-----QSALVKFLTQHEKDEIIKLNAEKKQREEEKLKKKLEQQ-----------------
-KIKEAKEKERQEKAKV-SPLEMFK---DTTLYSAWDE-QGLPTKDKDGNDITKSMTKKL
KKQWEQQKKLYEEFNGPLSS-------
>gi|121712962|ref|XP_001274092.	Aspergillus clavatus
------------------------------------------------------------
-------------------------------------------MAT--------------
----------------------------------------ARQQPP-----WRQPTVHPE
TEARLPPLKIWNSLTRSKTPFVPIDP--EAKK-VTW---------------YACG---PT
VYDDAHL------------------GHA-------------------RNYVSTDIIRRIM
RDYFHFDVKFIMNITDVDDKIILRARQQHLFNEFVTAHPVI-----DAEVLDVAKSAYTA
YLKKNLPLLSSELSPSQYQDEVEKVYAVVLNGGPLPGNEKAGDDEAKVKMHIKTVASAAK
VIAQAEAQDQSTTPSGFAESFYTNAQDLLLPYLDALKGSSINADDHSIFTKLTKKYEDRF
LK--DMRDLNVLDPDELTRVTEYGAEIADFVEKIVANKFGYVTD-----DGSVYFDINAF
EAA-GHPYARLEPWSRSDN-----KLLAEGEGALTKKT----TEKRSASDFALWKASKPG
EPSWTSSWGRG-RPGWHIECSAMASA-RLGKEMDIHSGGVDLAFPHHDNELAQSEAYWSH
DHSHTDQWVNYFLHMGHLSIQGS--KMSKSLKNFTTIREALERKEWTPRSLRIVFLLGGW
RDGVEITEELVSAGNSWEEKVN-----------------------NFFIKIRDPATLQAQ
TSG------------TDTTLPAALEAGRKAVHEHLCDSFNTQGAMFAISELISKYN----
--GAD-------KSTLN-AKDVEAVARFVTSMVNTFGLNGNATPES-AEIGWTGIDVPEE
AKPFLYPLSSMRDTLRQAARGKEGVTAESVVAIVNSASVPEQDVTDSAKPYADLLSNFRT
KVS--SLEQSEN----------VGKE---------ILALCDRVRDIDLFDLGVYLEDREN
-----LPALVRPVTK----ELIQAREEKAARARQKQIEKENKE-----------------
-----KEALKKLEKGKL-SHLDMFR----TNEYSAWDE-EGLPTRDAAGEEVTKSRAKKL
RKDWERQKKLHETWLASQMGAK-----
>gi|149730502|ref|XP_001496717.	Equus caballus
------------------------------------------------------------
------------------------MQSSRGALVGAPLLRAALGLGLGP------------
--------------------------------------GPRRAASEAHGQGWLQP----A
GYD--TGVKVYNSRTRRKDPLIVGS----ADA-TSW---------------YSCG---PT
VYDHAHL------------------GHA-------------------CSYVRFDIIRRIL
TRVFGCNIIMVMGITDVDDKIIRRARE---------------------------------
------------------------------------------------------------
--------------------------------------------MNVSPTSLANLYEEDF
KQ--DMAALKILPPTVYLRVTENIPQIISFIEGIIAKGHAYSTA-----KGNVYFDLQSR
GDK----YGKLVGVAPGPV-----GEPVE-------------SDKRHASDFALWKAAKPQ
EMFWASPWGNG-RPGWHIECSTISSL-VFGSQLDIHSGGIDLAFPHHENEIAQCEVFHQC
-----KQWGNYFLHSGHLHVKGKEEKMSKSLKNYITIKDFLKT--ASPDVFRLFCMRSSY
RSAIDYSDGAVLEAKHLLLAAT-----------------------AFVEDARAYMRGQLA
CGP-----------IGEDVLWERLSHTKGAVKAALADDFDTPGAVDAVMDLIHHGNRQLK
AVTKE-------PGGPRSPAVFGSIVSYIEQFFETVG----ISLA---DRQFVS----GD
SGS------------------------------------------ATLHSVVEELVRFRL
KVRQFALATGEATREARRQQLLERQP---------LLEACDTLRQD-LVAHGISIKDRSS
------------------------------------------------------------
--------------------------------TSTWEL-LGQRAQDHKPGS---------
---------------------------
>gi|47213255|emb|CAF92916.1|	Tetraodon nigroviridis
------------------------------------------------------------
-------------------------------------------KA---------------
----------------------------------------KRVQPP-----WSPP----A
GTDG-PRLRLYNSLTRAKVRGRPPDA--DAAL-VPFQRLIPELIP-----ALCSGAVRPS
ERQQSHLVQLRAHGVRRLTHGTRQVRHAHTRTHTRALTHTLTPSPPRRSYISFDILRRIL
RDYFKYEVFYCMNITDIDDKIIKRARQNFLLDQYKEKGPQ------AAQVLQDVRRAREP
FQAQLAATADPD-----KKQMLERLD----------AAVSAALQPLQAALEARAAEEALR
PL---------------AQALLENSKDLLADWLDRQAGSQVT--ENSIFFSLPKFWEEEF
HK--DMEALNVLPPDVLTRVSEYVPEIVDFVAKVISNGYGYES------NGSVYFDTAKF
DASPQHSYAKLVPEAVGDQ-----KALQEGEGDLSVSAERL-SEKKSPNDFALWKASKPG
EPSWDSPWGKG-RPGWHIECSAMAGT-VLGESMDVHGGGFDLRFPHHDNELAQSEAFFDN
-----DHWVRYFLHTGHLTIAGC--KMSKSLKNFITIKEALAK--NTARQLRLAFLMHSW
KDTLDYSSNTMESAVQYERFLNVGGRPQVAADALCLSLTCRDAAQEFFLNVKDVLRAPTD
VAG-----RFQKWEAAEAELNSSFFDRKSAVHEALCDNVDTRAAMEEMRLLVGQSNSYMA
SRKNA-------RSSPN-RMLLESIARYLTHMLKIFG----AVEEL-ASIGFPV-----G
QKE------NM-------------------------------DLESAVMPYLSVLSDFRA
DVR--KIAREQKGEGTRGFGVGGVLQNPPFCAVTPLLQLCDAVRDDTLPELGVRLEDHEG
DGALPLPGVRGPRTRSSRLLVFQMEEEKRLKKEEAARRKQEQEVFPSGGSVFSLSLQPSL
HRFLFPFQVAKLAKMKI-PASEMFLA--ETEKYSKFDP-TGFPTHDADGKELSKGQAKKL
RKLYEAQEKLHQEYLQT----------
>gi|157074020|ref|NP_001096719.	Bos taurus
------------------------------------------------------------
-----MAGSTTEHAPDYTAILGISDEAARLRALDAYLSTRSYLQGFALSQVDVDAFRQLS
GPPADPQLFHVARWFRHVTAILGSPPAARPPCGLQATGGGRRAQPT-----WSPP----A
GSEP-CQLRLYNSLTRRKDVFVPQD----GRR-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
RDYFKFDVFYCMNITDIDDKIIKRARQNFLLERYRETQPQ------AAQLLEDVRAALQP
FSAKLQETVDPD-----KKQMLERLQ----------HAVAQAAEPLEGALRAGQAGQELD
GR---------------VQALLEEAKDVLSDWLDSMHGSEVT--DNSIFSELPKFWEAEF
HK--DMEALNVLPPDVLTRVSEYVPEIVDFVQKIVDNGYGYAS------NGSVYFDTVKF
ANTEGHSYGKLVPEAVGDQ-----KALHEGEGDLSVSAERL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGT-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSANTMESALQYERLLN-----------------------EFFLNVKDLLRAPVE
VAA-----QFEKWEDEETELNKSFYKKKAAVHQALCDNIDTRTVLEEMRALVGQCNLYMA
ARKAA-------RRRPH-RVLLESIAHYLTHMLKIFG----AIEEE-SSLGFPI----GG
AGT------SL-------------------------------NLESTVMPYLQVLSEFRE
GVR--RIAREHR-----------VPE---------VLQLSDALRDNVLPELGVRLEDHEG
-----LPTVVKLVDR---DALLREREDKKRAEEEKRKKKEEAT-----------------
-RKRQEQEAAKLAKMKI-PPSEMFLS--ESDKYSKFDE-NGLPTHDTEGKELSKGQAKKL
RKLFEAQEKLHLEYLQLVQNGGPP---
>gi|125807796|ref|XP_001360523.	Drosophila pseudoobscura
------------------------------------------------------------
-------------------------------------------MS---------------
----------------------------------------KRVQPA-----WQAP----K
PAER-PKLRLYNSLTRQKEDFVPLD----GNN-VTW---------------YSCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRIL
ADYFGYNIHYVMNITDIDDKIIKRARQNHLFEEYAGESANLP----LDQLLGHQKEVLVR
FQETCAKNTDPD-----KKVMLDKTL----------QRMNDAVVALTTAVSQGDEKGIAE
K----------------RQHYLNEAKDPIAEWLDGKKGAEIN--DNAVFESLPRFWEDQF
HN--DMKSLNILPPDVLTRVSEYVPQIVAFIQKIIDNGLAYAA------NNSVYFDVNGF
DRKEKHHYAKLVPEAYGDT-----KSLQEGEGDLSVAEDRL-SEKRSANDFALWKASKAG
EPWWDSPWGRG-RPGWHIECSAMASD-IFGSTFDIHTGGVDLKFPHHDNELAQSEAAFNE
-----SEWVKYFLHTGHLTIAGC--KMSKSLKNFVTIQEALKK--HSATQLRLAFLLHSW
KDTLDYSENTMEMATQYEKFLN-----------------------EFFLNVKDLTRHVLS
EEPRR---QFDAWTDVEAALQKKFSSSQVQVHAALCDNVDTRSALDAIRELVSASNVYI-
--RDN-------KSRLN-SLLLRNVATYITDLLHVFG----AIAGPRGGIGFPV---SGG
AGP---QAAGG-------------------------------DLETTVLPYVQTLAEFRN
LVR--EQAKALK-----------AFD---------ILKLCDDLRDNILPNLGVRLEDKDG
-----GKFAVKLVDR---DSLLREREAKLAAEAEKAAEKERKK-----------------
-QAVAAAAAAKDAQRRV-NPKQMFLG--ETEKYSAFDE-NGLPTLDKEGKEISKGQVKKL
QKLQQQQEQRYKEYLASIKEA------
>gi|83768602|dbj|BAE58739.1|	Aspergillus oryzae
------------------------------------------------------------
-----------------------------------MAELKASIAGT--------------
----------------------------------------AGKSPP-----ATIRGDSTS
LTPGSHRNQNCHSYRCGLTPFIALDP--KGRK-VTW---------------YACG---PT
VYDDAHL------------------GHA-------------------RNYASTDIIRRIL
KDYFKFDVEFVMNITDVDDKL---------------------------------------
------------------------------------------------------------
------------------------------------RGSTVPGDAYEIFTKLTKKYEEHF
MR--DMRDLNVLDPDEITRVTEYGQEIADFVEKIVTNDFGYVTL-----DGSVYFDIKSF
EKA-GHPYAR------------------DGEGTLSHA-----VEKRSPDDFAIWKASRPG
EPSWKSQWGQG-RPGWHIECSAMASS-RLGSQNDIHSGGIDLAFPHHDNELAQSEAYWSE
---KKQQWVNYFLHMGHLSIQGS--KMSKSLKNFAT------------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------S-CGIGWEGTDIPEP
AKQFLYPLSAMRDALREATKSQGEVTHQQLKAITAETIVDERLVSQASRPYFQVFRDFHA
RISPSNSEDTPT----------SSKE---------LLSLCDRLRDVELFDLGIYLEDREN
-----KPALVRPVTR----DLLQSREEHARKMLLKQQEKEKQE-----------------
-----KLAKERLEKGRL-SHLDMFR----TSEFSAWDE-DGMPTKDAVGEPINKSRSKKL
RKGWERQKKAHEAWVASQRTDS-----
>gi|157105607|ref|XP_001648945.	Aedes aegypti
------------------------------------------------------------
-------------------------------------------MA---------------
----------------------------------------KRVQPT-----WQTP---VQ
SSEE-PKLRLYNSLTRQKELFVPKD----GKN-VKW---------------YSCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
TDYFGYNVLYVMNITDIDDKIIKRARQNYLYERYVERTTS------LETLLDDNKEVMEA
FQGNLSKTTDPD-----KKAMMERML----------EKLTAAVDNLTIAVKTGEEGKVKE
A----------------QSRFLEDSKDPLSDLLDKKEGASVN--ENSIFETLPRYWEDEF
HK--DMNALNVLAPDVLTRVSEYVPQIVEYIQKIIDNGLAYEA------NGSVYFDVAGF
DKREKHYYAKLVPEAYGDA-----KSLQEGEGDLSTTEDRL-SEKRSPNDFALWKNSKAG
EPWWNSPWGKG-RPGWHIECSAMASD-ICGDYLDIHTGGVDLKFPHHDNELAQSEAHDNS
-----SEWVKYFLHTGHLTIAGC--KMSKSLKNFVTIQQALQK--HTATQLRLAFLLHSW
KDTLDYSENTMEMAVQYERFLN-----------------------EFFLNVKDLTRHVVS
GKPRD---QFNLWTPVEADLQQKLNATKDAVHVALCDNIDTRSALDAVRDLVSHSNVYI-
--RDH-------KNELN-ALLLRRIAGYITDLLHIFG----AINGPRGGIGFPV----GG
SAG------SA-------------------------------DLEETVMPYLVALSDFRT
AVR--EQARTLK-----------ATD---------ILQLCDQIRDDILPNLGVRLEDREG
-----NLSALKLVDR---DVLLKEREAKRAEEARKVAEKERKK-----------------
-AEAAATQAAKDAQRKI-NPVDMFRS--ETDKYSAFDE-RGLPTHDTEGKEISKGQQKKL
QKLQQQQEKRYQEYLEPVKA-------
>gi|109105037|ref|XP_001096302.	Macaca mulatta
------------------------------------------------------------
-----MAGSSGQQAPDYRSILSISDEAARAQALNEHLSTRSYVQGYSLSQADVDAFRQLS
TPPADPQLFHVARWFRHIEALLGSPCGKGQPCRLQAS-KGRRVQPQ-----WSPP----A
GTQP-CRLHLYNSLTRNKEVFIPQD----GKK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
KDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYLEKRPE------AAQLLEDVQAALKP
FSVKLNETTDPD-----KKQMLERIQ----------HEVQLATEPLEKAVQSRLTGEEVN
SC---------------VEVLLEEAKDLLSDWLDSTLGSDVT--DNSIFSKLPKFWEGEF
HR--DMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVS------NGSVYFDTAKF
ASSEKHSYGKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGT-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSSNTMESALQYEKFLN-----------------------EFFLNVKDILRAPVD
ITG-----QFEKWGEEEAELNKNFYDKKTAIHEALCDNVDTRTVMEEMRALVSQCNLYMA
ARKAM-------RKRPN-RALLENIALYLTHMLKIFG----AIEEE-SSLGFPV----GG
SGT------SL-------------------------------NLESTVMPYLQVLSEFRE
GVR--KIAREQK-----------VPE---------VLQLSDALRDDILPELGVRFEDHEG
-----LPTVVKLVDR---NTLLKEREEKRQVEEEKRKKKEEAA-----------------
-RRKQEQEAAKLAKMKI-PPSEMFLS--ETDKYSKFDE-NGLPTHDAEGKELSKGQAKKV
KKLFEAQEKLYKEYLQMPQNGSFQ---
>gi|75075917|sp|Q4R550|SYCC_MAC	Macaca fascicularis
------------------------------------------------------------
------------------------------------MAGSSGQQGKG-------------
----------------------------------------RRVQPQ-----WSPP----A
GTQP-CRLHLYNSLTRNKEVFIPQD----GKK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
KDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYLEKRPE------AAQLLEDVQAALKP
FSVKLNETTDPD-----KKQMLERIQ----------HEVQLATEPLEKAVQSRLTGEEVN
SC---------------VEVLLEEAKDLLSDWLDSTLGSDVT--DNSIFSKLPKFWEGEF
HR--DMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVS------DGSVYFDTAKF
ASSEKHSYGKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGT-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTITGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSSNTMESALQYEKFLN-----------------------EFFLNVKDILRAPVD
ITG-----QFEKWGEEEAELNKNFYDKKTAIHEALCDNVDTRTVMEEMRALVSQCNLYMA
ARKAM-------RKRPN-RALLENIALYLTHMLKIFG----AIEEE-SSLGFPV----GG
SGT------SL-------------------------------NLESTVMPYLQVLSEFRE
GVR--KIAREQK-----------VPE---------VLQLSDALRDDILPELGVRFEDPEG
-----LPTVVKLVDR---NTLLKEREEKRQVEEEKRKKKEEAA-----------------
-RRKQEQEAAKLAKMKI-PPSEMFLS--ETDKYSKFDE-NGLPTHDAEGKELSKGQAKKV
KKLFEAQEKLYKEYLQMPQNGSFQ---
>gi|115741226|ref|XP_001190614.	Strongylocentrotus purpuratus
------------------------------------------------------------
--------------------------------------MSTFLQGK--------------
----------------------------------------KRCQPE-----WEPP----S
GAQK-AQLRHFNSLTRQKELFVPQE----GKR-VSW---------------YSCG---PT
VYDAAHM------------------GHA-------------------RSYISFDILRRVM
TKYFNYDVTYVMNITDVDDKIIKRARTNYLYDQYLSNTTS------VEQVLADVRQALEP
YQAKMNKEASAD-----KKDMLMKII----------NKVREALAKCEAA--------KSE
EL---------------KQVLLTEAKDPLAEMLDAQKGCDVS--DKSIFSVLPQHWEAEF
HS--DMNALNVLPADVLTRVSEYVPEVIDYVQKIIDRGFGYES------NGSVYFTTSKF
DNDDSHHYAKLVPEAYGDQ-----AALAEGEGDLSISPDQL-QEKQSANDFALWKNSKPG
EPEWESPWGMG-RPGWHIECSAMASS-ILGESMDIHTGGADLKFPHHDNELAQAEAHYGN
-----DDWVRYFLHSGHLTIQGC--KMSKSLKNFITIKQALET--YSSRQIRLVFLLHSW
KDTLDYSTATMECAVQYEKMIN-----------------------EFFLNVKDIIHNSPR
EGCE----AFHKWTTLEIRLNKQYLECQEKVHSTLCDSIDTKSALDAIRAVVNQCNVYIQ
ERRGA-------KDSPN-AFLLGSIAKYITKMFKIFG----AIEGE-ELLGFPV----GG
ASE------SG-------------------------------NVEQTVLPYLKVLAEFRQ
TIR--QKAR--------------------------ILQ----------------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------
>gi|58393703|ref|XP_320253.2|	Anopheles gambiae
------------------------------------------------------------
-------------------------------------------MA---------------
----------------------------------------KRVQPT-----WQAP----E
EKPA-PKLYLYNSLTRRKELFVPRD----GRN-VHW---------------YSCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
SDYFGYNVLYVMNITDIDDKIIKRARQNHLYERYLQQSKDMP----LERLLDDSKEVMAT
FRENLARTTDAD-----KKTMMDRML----------EKLTAAVDNLSLAVKEGDEG-RIQ
QA---------------QDQFLQDSKDPLADLLDSKQGSSVT--ENAIFETLPRYWEDAF
HK--DMAALNVLQPDVLTRVSEYVPQIVTYIEKIIANGLAYEA------NGSVYFDVAGF
DRREQHHYAKLVPEAYGDA-----KQLQEGEGDLSIGADRL-TEKRSANDFALWKSSKAG
EPWWDSPWGRG-RPGWHIECSAMASD-ICGDYLDIHTGGVDLKFPHHDNELAQSEAHDGS
-----AEWVKYFLHTGHLTIAGC--KMSKSLKNFVTIQQVLEK--HTATQLRLAFLLHSW
KDTLDYSDNTMEMAVQYERFLN-----------------------EFFLNVKDLTRHVQT
GPARD---AFDRWRPVEAELERKFADARAAIHEALCDNVDTRTALDVMRGLVSACNVYIK
EHRSA-------GF--N-ALLLRRVAAYCTDLLHIFG----AISGPRGGIGFPISAGAAG
DGT----GMAG-------------------------------DLEQTVMPYLQALAEFRN
AVR--EQARGLK-----------ATE---------ILQLCDQLRDDVLPGLGVRLEDREG
-----APSALKLVPA---EVLLREREAKRAEENRKAAEKERKK-----------------
-AEAAAAQAAKDAQRKI-NPLDMFRS--ETDKYSAFDDATGLPTHDLEGKEISKGQLKKL
QKLQQAQEKRYQEYLASQA--------
>gi|91091952|ref|XP_968189.1|	Tribolium castaneum
------------------------------------------------------------
-------------------------------------------MS---------------
----------------------------------------KRVQPP-----WSAP----E
ASGG-PVLKVFNSLTRQKEVFRPIS----GKK-VTW---------------YSCG---PT
VYDASHM------------------GHA-------------------RSYITFDILRRVL
ADYFGYDIFFVMNITDIDDKIIKRARQNYLFERYVGEERS------LQEVLSDAKLVLEK
LAETTQNAFDPD-----KKQMYEKLL----------VNLTKSVEELENAVKSGDNT-KIE
NA---------------KKNYIVRSKDPLSDWLDCKFGATIT--DNAIFTSLPQHWEQEF
HK--DMEALNILKPHVLTRVSEYIPEIIGYISRIISNGFGYEA------NGSVYFDVAAF
DKQPNHYYAKLVPEAYGDT-----NSLQEGEGDLTTADQR--NEKHSPNDFALWKRSKPG
EPAWDSPWGKG-RPGWHIECSAMAST-IFGDTLDIHTGGVDLKFPHHDNEIAQSEAHFGA
-----SEWVKYFLHSGHLTIAGC--KMSKSLKNFVSIQDALAK--YTARQLRFAFLLHAW
RDTLDYSQNTMEVALQYEKNFN-----------------------EFFLNVKDLTRNFLK
KPTLVG--HYVKWERQEMELNGHFLQAKDNVHAALCDNIDTRTSLESLRDLVTASNLYI-
---RD-------KNPPN-CLLLHDIAVYITKMLSIFG----AISEP-SRVGFPV-----T
SGN------ES-------------------------------NSEDKILPYLEILADFRD
KIR--TSARTLK-----------ATE---------ILQECDKLRDETLPNVGVRLEDREG
-----APSAVKIVGR---DILLKEKEAKKLLELEKAKEKERKK-----------------
-AELAAAQAAKEAQKKI-PPSEMFKL--EKDKYSKFDE-NGLPTHDVHGKEISKGQLKKL
QKLQQAQEKKHQEFLATLS--------
>gi|58332582|ref|NP_001011365.1	Xenopus tropicalis
------------------------------------------------------------
-------------------------------------MTDSWERGKG-------------
----------------------------------------RRTQPP-----WSAP----N
TQAQ-PGLRLYNSLTRSKELFVPQD----GNK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
RDYFKYDVFYCMNITDIDDKIIKRARQRHLFQQYRERNPR------PSDLLQDVSAALTP
FLQRISEANDPD-----KRQMLERIH----------GSVSAALLPLQDAVSSNARAEELE
RL---------------SQELMEAAVDLLSDWLDEKHGAQIT--DNSIFSQLPKHWESEY
HR--DMEALNVLPPDVLTRVSEYVPEIVAFVQRIVDNGYGYVS------NGSVYFSTAKF
HASEKHYYAKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKQSPNDFALWKASKPG
EPSWESPWGKG-RPGWHIECSAMAGS-ILGESMDIHGGGFDLRFPHHDNELAQSEAYFDN
-----DHWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALQK--NTARQLRLAFLMHAW
KDTLDYSSNTMESAVQYEKFMN-----------------------EFFLNVKDLLRAPTD
VTG-----QFVKWEVPELELNSCFYSKKAAVHEALCDNIDTRTVMEEMRSLVSQCNSYIA
SRKAA-------KQPPN-RLLLRSVSSYLTAMLKVFG----AIEGE-EVIGFPI----GG
SDN------SM-------------------------------NLESTVMPYLQVLSQFRE
GVR--QIARQHK-----------VTE---------VLQLSDLLRDDVLPELGVRLEDHEG
-----LPTVVKLVDR---ETLLKEKEEKRKAEEEKQRKKEEAA-----------------
-RKKQQQEAAKLEKMKV-SPSQMFQL--ETDKYSQFDE-SGFPTHDTEGKELSKGQSKKL
RKLYEAQEKLHKEYLQMAQNGTTG---
>gi|19922364|ref|NP_611087.1|	Drosophila melanogaster
------------------------------------------------------------
-------------------------------------------MS---------------
----------------------------------------KRGQPA-----WQAP----E
AVDR-PKLKLFNSLTRQKEDFVPLD----GNN-VTW---------------YSCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRIL
SDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLP----LDELLGQQKEVLQR
FQDTCAKNTDPD-----KKIMLDKTL----------QRMNDAVEALTKAVGKGDEREISE
K----------------RLLYLNEAKDPISDWLDSLKGAQIN--DNAVFEALPRYWEDQF
HN--DMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYAA------NNSVYFDVNGF
DKREKHHYAKLVPEAYGDT-----KSLQEGEGDLSIAEDRL-SEKRSANDFALWKASKAG
EPWWDSPWGKG-RPGWHIECSAMASD-IFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNE
-----SEWVKYFLHTGHLTIAGC--KMSKSLKNFVTIQEALKK--HSATQLRLAFLLHSW
KDTLDYSENTMEMATQYEKFLN-----------------------EFFLNVKDLTRHVLS
EEPRR---QFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSNVYI-
--RDN-------KTRLN-SLLLRNVATYITDLLHVFG----AISGPRGGIGFPV---SGG
SGA---QAAGA-------------------------------DLETTVLPYVQSLAEFRY
LVR--EQAKTLK-----------AFD---------ILKLCDDLRDNVLPNLGVRLEDKDI
-----GKYAVKLVDR---DSLLREREAKLAAEAEKAAEKERKK-----------------
-QAAAEAAAAKEAQRRV-NPKEMFLA--ETEKYSAFDE-NGLPTHDKEGKEVSKGQIKKL
QKLQQQQEQRYNEYLASIEKA------
>gi|62641665|ref|XP_215134.3|	Rattus norvegicus
------------------------------------------------------------
-----MAGSSAEQAADYRSILSISDEAARVQALDQHLSTRSYIQGYSLSQADVDVFRQFS
APPADSRLFHVARWFRHIEALLGGPQGRGEPCRLQAS-KGRRVQPQ-----WSPP----A
GTEP-CRLRLYNSLTRNKDVFIPQD----GKK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
RDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQYREQKPS------AAQLLKDVGDAMKP
FSVKLSETTDPD-----KRQMLERIQ----------NSVKLATEPLEQAVHSNPSGEEVD
SR---------------VQVLLEEAKDLLSDWLDSTGGSEVT--DNSIFSKLPKFWEEEF
HK--DMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYAS------NGSVYFDTAKF
AASEKHSYGKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGS-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSSNTMESALQYEKFMN-----------------------EFFLNVKDILRAPVD
ITG-----QFEKWEAEEVELNKNFYDKKTAVHEALCDNIDTRTVMEEMRALVSQCNLYMA
ARKAA-------RRRPN-RALLENIAMYLTHMLKIFG----AIEEE-NPLGFPV----GG
PGT------NL-------------------------------NLESTVMPYLQVLSEFRE
GVR--KIAREKK-----------VLE---------VLQLSDALRDDILPELGVRFEDHEG
-----LPTVVKLVDR---DTLLKEKEEKKRAEEEKRRKKEEAA-----------------
-RKKQEQEAAKLAKMKT-PPSEMFRS--ETDKYSKFDE-NGLPTHDTEGKELSKGQTKKL
KKLFEAQEKVYKEYLQQLQNSSLQ---
>gi|19173375|ref|NP_597178.1|	Encephalitozoon cuniculi
------------------------------------------------------------
------------------------------------------------------------
---------------------------------------------------MDKT-----
-------LKLYNSITRTIDIFTPRK----GNE-VKM---------------YICG---PT
VYDSSHI------------------GHA-------------------RTYVMFDVIRRVL
SDYLKYNVRFVMNITDIDDKIIARANET--------------------------------
------------------------------------------------------------
-------------------------------------GASME--------EVTRKYTEEF
FE--DMKTLNVRSPSFVTFVTSYVDKIVKFIEKLEANGLAYES------RGSVYFDLNSY
QQ--RYSY----PLFKSKD-----GINSEGDEN---------KDKRSPCDFVLWKRSKEN
EPRYESKWGHG-RPGWHIECSVMSSD-ILGEDLDIHAGGVDLAFPHHENEIAQCQAYFMQ
-----EPWVKCFLHTGHLNISGL--KMSKSLKNFTTIKEALKT--ISPRQLRVLFLHHQW
NKDMNYEKEHLKFAETIEKKIF-----------------------NFMSVAESMRKNAL-
--------AFETLENADREVLRELGNVQEAVHAALLDNVDTPAVMKRIVEMINFTNARI-
-------------KTIS-PSTVLVVKDYIKEITDVLG----LSEEERQE--SPG------
--------------------------------------------EDLI---AQLLSNFRE
SIR--EMARRKE----------PYSK---------FLEKCDWIRES-IKDYGYIIEDNSE
------------------GSILRKK-----------------------------------
------------------------------------------------------------
---------------------------
>gi|156547291|ref|XP_001606432.	Nasonia vitripennis
------------------------------------------------------------
-------------------------------------------MS---------------
----------------------------------------KRLQPS-----WSPP----E
CKSG-PPLKLYNSLTRQKEEFVPQY----RNR-VLW---------------YSCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
SDYFNFDVVYVMNITDIDDKIIKRARQNHLYENYLAENHS------LDQILSDAKSVMQT
FENTVKTTTDPD-----KRTMYERML----------IRVKESIEKLEVAVKSNNQA-QIK
EC---------------QDVLLKESKDPLSDWLDKKKGDTVT--EHSIFSKLSQHWENDF
HK--DMDALNVWRPNVLTRVSEYVPEIVAFIEKIIANGLAYES------NGSVYFDVKAF
DKSEKHYYAKLVPEAYGDT-----SSLQEGEGDLSVSADRL-SEKRSVTDFALWKSSKAG
EPWWDSPWGKG-RPGWHIECSVMASA-ICGESLDIHTGGVDLKFPHHDNELAQAEAYFDN
-----SHWVRYFLHSGHLTISGC--KMSKSLKNFITIKEALKK--HSARQLRLAFLLHSW
KDTLDYGDATMDMAVQYEKFLN-----------------------EFFLNVKCRIRKIGS
AGTTIN--TFDKWGQQEVELNNKFCAAKDDVHNALCDNIDTRTALDIIRELVTTSNIYI-
---KD-------CQKPN-TLLLRDIAVYITKIFTVFG----AIATH-DSIGFPL----ED
ESK------NV-------------------------------NLEETIMPYLEILSEFRE
KVR--GHARLLK-----------ATD---------ILQECDRLRDDILPNVGVRLEDQEG
-----ANAQVKLCNR---EELLREREQKKRQEAEKAAEKEKKK-----------------
-AEAAAAAAAKEAQKKI-PPKEMFRS--ETDKYSQFDE-NGLPTHDLEGKEVSKGQLKKL
QKLQQAQEKRYNEYLASIQNGS-----
>gi|118084394|ref|XP_416955.2|	Gallus gallus
------------------------------------------------------------
----------------------MLLGAAVRRGRAGGGAARRWRSG---------------
----------------------------------------AAPRRE-----WVPP----A
GRA--CGVVAYNSRSRSKEPLVLAK----DGV-ATW---------------YSCG---PT
VYDHAHL------------------GHA-------------------CSYVRFDIIRRIL
TRFFETEVIMVMGITDIDDKIIRRANEMNI------------------------------
------------------------------------------------------------
--------------------------------------SPVA---------LARIYEEDF
KQ--DMASLKVLPPTVYMRVTENIPQIISFIKTIIANGQAYATS-----QGNVYFDVNSW
GER----YGVLTAVSPDTQ-----GEAVD-------------TDKRHGRDFALWKAAKPQ
ELSWSSPWGKG-RPGWHIECSTISSA-VFGKQLDIHTGGIDLAFPHHENEIAQCEVYHQC
-----EQWGNYFLHSGHLHVKGSQEKMSKSLKNYITIKDFLKK--FSSDQFRMFCLRSRY
SSAVEFSDETMNDAKNVLQAIS-----------------------SFIRDANAYIKGQLV
CDP-----------VREDVLWERLASTKVNVKAAFADDFDTSRAVAAIMDLIHHGNRQLK
AVTKD-------AVSPRSSVVYGSITSYIESFFNALG----MSLEE-RQ--VAV----GG
GNT---------------------------------------ALLSNVM---DELVSFRT
KVR--NYALVLP----------EATE---------AVQMEEGAVGAKGPKQEQKEKRRQL
-----MQERKPLLEA---CDSLRGDLAAFGIHIKEQGSKLRWL-----------------
-VEILPSLYLHPHTKRVGPHMRVCSS--LLELYNTFPG----------SRTTSLSMDRST
ASTWEMAEGGRAEQQAEEKS-------
>gi|147899657|ref|NP_001080786.	Xenopus laevis
------------------------------------------------------------
-------------------------------------MTESWEQGKG-------------
----------------------------------------RRTQPP-----WSAP----N
TNEQ-PGLRLYNSLTRSKELFFPQV----GRK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
RDYFKYDVFYCMNITDIDDKIIKRARQRHLFQQYRESNPP------HSDLLQDVNTALIP
FLQRISETNDPD-----KKQMLERIQ----------TAVSAALLPLQDALNKNTGAEELQ
KH---------------SQVLMEAAVDLLSDWLDEKHGAQIA--DNSIFSQLPKYWEGEY
HK--DMEALNVLTPDVLTRVSEYVPEIVAFVQKIVDNGYGYVS------NGSVYFSTAKF
HDSENHFYAKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKQSPNDFALWKASKPG
EPSWESPWGKG-RPGWHIECSAMAGS-ILGESMDIHGGGFDLRFPHHDNELAQSEAYFDN
-----DHWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALQK--NTARQLRLAFLMHSW
KDTLDYSNNTMESAVQYEKFMN-----------------------EFFLNVKDLLRAPTD
ITG-----QFVKWEVLEIELNNCFYSKKAAIHEALCDNIDTRTVMEEMRSLVSQCNSYIA
SKKVA-------KQFPN-RMLLRSISSYLTSMLKVFG----AIEGE-EVIGFPI----GG
SEN------SM-------------------------------NLESTVMPYLQVLSQFRE
GVR--QIARQHK-----------VTE---------VLQLSDLLRDDILPELGVRLEDHEG
-----LPTVVKLVDR---ETLLKEKEEKRKAEEEKQRKKEEAA-----------------
-RKKQQQEAAKLEKMKI-SPSQMFTL--ETDKYSQFDE-SGFPTHDTEGKELSKGQTKKL
RKLFEVQEKLHKEYLQMVQNGTTA---
>gi|70997892|ref|XP_753678.1|	Aspergillus fumigatus
------------------------------------------------------------
-------------------------------------------MAT--------------
----------------------------------------ARQQPP-----WRQPTEYPE
AKARLPPLKIWNSLTRSKNPFIPIDP--EGKK-VTW---------------YACG---PT
VYDDAHL------------------GHA-------------------RNYVSTDIIRRIM
RDYFHFDVKFIMNITDVDDKIILRARQQHLFNEFVSAHPTI-----TAEVLDIARNAYTA
YLKKNLPLLNPELPPAQYQEEVEKVYATVLNGGPLPGNEKAGDDEAKVKMHIKTVASAAK
VIAQAESLDQAATPKGFAESFYTNAQDLLLPYLDSLKASSINADDHSIFTKLTKKYEERF
MK--DMRDLNVLDPDELTRVTEYGAEIADFVEKIVENKFGYVTD-----DGSVYFDITAF
ENA-GHPYARLEPWSRSDN-----KLVAEGEGALTKKT----TEKRSASDFALWKASKPG
EPSWTSSWGRG-RPGWHIECSAMASA-KLGKQMDIHSGGVDLAFPHHDNELAQSEAYWSH
GHPHTDQWVNYFLHMGHLSIQGS--KMSKSLKNFTTIREALERKEWTPRSLRIVFLLGGW
RDGVEITEELVSAGNSWEDKVN-----------------------NFFIKMKDPATLSGQ
TSG------------SDTTLPAALEAAKKATFDHLCDSFNTQGAMSAISELISKYN----
--SAD-------KSTLN-PKDVEAVARWVTSMVNIFGLNGSATADS-TEIGWSGIDVPEE
AKPFLYPLSSMRDSLRQAARAKEGVTPETVAEIVSKGDVPELDLTESAKPYAELLSNFRT
KVS--SIQPSES----------LGKE---------ILALCDRVRDIDLFDLGIYLEDREN
-----LPALVRPVTR----ELIQAREEKAARARQKQIEKENKE-----------------
-----KEALKKLEKGKL-SHLEMFR----TNEYSAWDE-DGIPTRDAAGEEITKSRAKKL
RKDWERQKKLHETWLASQMGAK-----
>gi|114635634|ref|XP_001156119.	Pan troglodytes
------------------------------------------------------------
-----MADSSGQQAPDYRSILSISDEAARAQALNEHLSTRSYVQGYSLSQADVDAFRQLS
APPADPQLFHVARWFRHIEALLGSPCGKGQPCRLQAS-KGRRVQPQ-----WSPP----A
GTQP-CRLHLYNSLTRNKEVFIPQD----GKK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
KDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPE------AAQLLEDVQAALKP
FSVKLNETTDPD-----KKQMLERIQ----------HAVQLATEPLEKAVQSRLTGEEVN
SC---------------VEVLLEEAKDLLSDWLDSTLGCDVT--DNSIFSKLPKFWEGDF
HR--DMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVS------NGSVYFDTAKF
ASSEKHSYGKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGT-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSSNTMESALQYEKFLN-----------------------EFFLNVKDILRAPVD
ITG-----QFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMA
ARKAM-------RKRPN-QALLENIALYLTHMLKIFG----AVEED-SSLGFPV----GG
PGT------SL-------------------------------SLEATVMPYLQVLSEFRE
GVR--KIAREQK-----------VPE---------ILQLSDALRDDILPELGVRFEDHEG
-----LPTVVKLVDR---NTLLKEREEKRRVEEEKRKKKEEAA-----------------
-RRKQEQEAAKLAKMKI-PPSEMFLS--ETDKYSKFDE-NGLPTHDMEGKELSKGQAKKL
KKLFEAQEKLYKEYLQMAQNGSFQ---
>gi|126275747|ref|XP_001387132.	Pichia stipitis
------------------------------------------------------------
-----------------------------MNLLRKLFTRFISMSTVK-------------
----------------------------------------KVTQPE-----WHAPQ--PS
AVGK-PVLKIYNSLTRSKTEFVPIV----PGH-ITW---------------YCCG---PT
VYDHSHM------------------GHA-------------------RNYVSTDICRRIF
QDYFGYNVKFIQNVTDIDDKIIIAARQQYLFEQKLSGVYQQV----NSELVAKSEEYLTS
YVEKNLPEFT-------GKDIKSEFI--AWADSIASNVQDIAKEKPKFPMYLKAARRAHD
AIYSTNVLATP------IAEYLESIKEVATPLLDKEFGSTVN--DPSIFRKLPSFWENKF
DQ--DMARLNVLPSTVTTRVSEYIPDIIEFIDKIIENGFGYPTK-----DGSVYFDTAKF
ENDPNHDYAKLQPWNKGDM-----SLINDGEGSLTTGQD----TKKSSADFALWKASKPG
EPSWPSKWGEG-RPGWHIECSVMASD-ITGQTMDIHSGGIDLCFPHHDNELAQSEAYFDN
-----KQWVNYFMHSGHLHIQGQ--KMSKSLKNFITIEQALED--FSSRQLRLVFALSSW
EKPLDFKDSLISEVKTIESAFS-----------------------KFFTNVRALNNDYKH
KVNDGEF-VSKKLSKYEKQLYDDLDIAQDEVDVAFNDNLASGQALRAIQILISKSNNYIQ
LAASG-------ETELR-IDVLLQVTRWIVKILEILG----FEARA-DRLGWVD-SSEAG
EGA-------G-------------------------------STEDIALPYVKALSQFRD
AVR--NLAISKA----------DNSE---------ILKACDTIRSD-LINLSVSLDDRPS
-----GAALVKFLNALEKEQLIQQQEDKLKAIAEKEKKKQEQA-----------------
-AAAAKKEEERLAKMKI-NPQDMFK---DSSLYSTWDE-RGIPTKDAKGEDVSKSMQKKL
TKQHQQQQKLYDEYLASQKA-------
>gi|73982653|ref|XP_851224.1|	Canis familiaris
------------------------------------------------------------
-----MSGSSGEQAPAYRSILSISDEAARVQALNEHLSTRSYVRGYSLSQADVDAFRQLS
APPADTRLFHVARWFRHIEAILGGPCARGEPCGRQAS-KSRRGQPQ-----WSPP----A
GSPP-CKLRLYNSLTRNKDVFIPQH----GKK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
RDYFGYDVFYCMNITDVDDKIIKRARQNYLFEEYREKQPR------AAQLLEDVHAALKL
FSVKLQETTDPD-----KKHMLERIQ----------HTVQLAAEPLERAVQNDLPAEVAD
SC---------------AEVLLEEAKDLLSDWLDSTLGSEVT--DNSIFSKLPKFWEEEF
HK--DMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYAS------NGSVYFDTVKF
ASSERHSYGKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGT-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSSNTMESALQYEKFMN-----------------------EFFLNVKDLLRAPVD
ISG-----RFEKWEDEESELNKSFYDKKAAVHEALCDNVDTRTVLEEMRALVSQCNLYMA
TRKAA-------RRRPN-RALLESIALYLTRMLKIFG----AIEEE-SSLGFPV----RG
PGT------SP-------------------------------DLESTVMPYLQVLSEFRE
GVR--KIAREQK-----------VPE---------VLQLSDALRDDILPELGVRLEDHEG
-----LPTVVKLGDR---EALLREREEKRRVEEEKRKKKEEAA-----------------
-RIKQEQEAAKLAKMKI-PPSEMFLS--ESDKYSKFDE-NGLPTHDVDGKELSKGQAKKV
KKLYEAQEKRHKEYLQMAQNGSLK---
>gi|10835051|ref|NP_001742.1|	Homo sapiens
------------------------------------------------------------
------------------------------------MADSSGQQGKG-------------
----------------------------------------RRVQPQ-----WSPP----A
GTQP-CRLHLYNSLTRNKEVFIPQD----GKK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
KDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPE------AAQLLEDVQAALKP
FSVKLNETTDPD-----KKQMLERIQ----------HAVQLATEPLEKAVQSRLTGEEVN
SC---------------VEVLLEEAKDLLSDWLDSTLGCDVT--DNSIFSKLPKFWEGDF
HR--DMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVS------NGSVYFDTAKF
ASSEKHSYGKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGT-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSSNTMESALQYEKFLN-----------------------EFFLNVKDILRAPVD
ITG-----QFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMA
ARKAV-------RKRPN-QALLENIALYLTHMLKIFG----AVEED-SSLGFPV----GG
PGT------SL-------------------------------SLEATVMPYLQVLSEFRE
GVR--KIAREQK-----------VPE---------ILQLSDALRDNILPELGVRFEDHEG
-----LPTVVKLVDR---NTLLKEREEKRRVEEEKRKKKEEAA-----------------
-RRKQEQEAAKLAKMKI-PPSEMFLS--ETDKYSKFDE-NGLPTHDMEGKELSKGQAKKL
KKLFEAQEKLYKEYLQMAQNGSFQ---
>gi|68363612|ref|XP_707456.1|	Danio rerio
------------------------------------------------------------
------MASAGDAAFDYGFLLRISEDSRLVEALNEYLSSRSYLAGYGPSQADAEAFALLC
RPPPE-RHVHALRWYKHIAFLKPQANDQSPEC---ST-KGKRVQPP-----WSPP----E
GTDI-SKLRLYNSLTRTKEVFVPQK----GNR-VLW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRIL
KNYFKYDVFYCMNITDIDDKIIKRARQNYLLEQYREKKPS------AAQILQDVLTARTP
FKAKLAETTDPD-----KKQMLERLD----------SAVDAALGPLQVAVQSKAAQDSIQ
KQ---------------AQVLLEEAKDLLSDWLDSQFGSQVT--ENSIFSLLPKYWEGEY
HK--DMEALNVLPPDVLTRVSEYVPEIVEFVKKIVDNGYGYES------NGSVYFDTAKF
DSCPAHSYAKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSQNDFALWKASKPG
EPSWDSPWGMG-RPGWHIECSAMAGS-ILGESMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DYWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALAK--HTARQLRLAFLMHSW
KDTLDYSNNTMESAIQYERFIN-----------------------EFFLNVKDILRSPTD
ITG-----QYEKWEAEEIELNKCFYDKKTSVHGALCDNIDTRSALEEMRALVGQSNTYMA
ARRSA-------KLPPN-RMLLQSIALYLTDMLKTFG----AIEGT-DPIGFPV----GG
NGQ------SA-------------------------------DLESTVMPYLSVLSDFRE
DVR--KIAREKK-----------VTE---------LLQLCDQLRDDTLPELGVRLEDRDG
-----LPTSVKLVDK---ETLLKEKEEKKKLKDDKRKKKEEAA-----------------
-RKKQEQEMAKLAKMKL-KPSEMFRS--ETDKYSSFDE-TGFPTHDAEGKELSKGLTKKL
RKLYETQEKLHNEYLQSTQNGS-----
>gi|45199158|ref|NP_986187.1|	Ashbya gossypii
------------------------------------------------------------
------------------------------MQSVLRLSVIRNMSGSV-------------
----------------------------------------KVVQPP-----WQKP---VR
AAEQ-PVLKLYNSLTRTKDEFIPLSQ---GRN-VTW---------------YSCG---PT
VYDASHM------------------GHA-------------------RNYVSIDINRRLI
EDYFGYHVEFVQNVTDIDDKIILRARQEHLYAEYVAAHPSV-----DQLVLADATEAVVQ
YFRKHLNP---------DLTTISAYE--QWYAKL--DLAREREANAKFAMHTAAVGRALD
ALENPT-----------VPGFLTAVKDVLVPLLDGRSGASVR--DPDVFRALAAHWENSF
NA--DMDRLGVRPPSVTTRVSEYVDEIVKFIERIVANGYAYATS-----DGSVYFDTVQF
EAG-GHAYPKCQPWNRGVA-----DLIADGEGALATG-----TEKQNPNDFALWKASKAG
EPEWPSPWGLG-RPGWHIECSVMASD-VLGERVDIHSGGIDLAFPHHDNELAQAEACFNS
-----QQWVNYFLHTGHLHIEGQ--KMSKSLKNFITIDEALKM--YSARQLRLAFAMSPW
GSPLDFKEATMVQVRGWESAMG-----------------------NFFRTVRALANDGDG
KT---------RPGVREAELRAHLADAAARVHENLCDNLSTHSVLRCLGELVGRANAYI-
--GAA-------GPEAR-VESVAAVARFCTRILAAMG----IPARA-DGLGWLE----QQ
AGA------AE-------------------------------AGEAAILPYVRCLARFRD
EVR--KGARGGD-----------TAR---------LLAITDRVRDVDLPALGVLLEDRQD
-----RPALVKFATP----EELKQRELEAEEKEKAARAAVRAK-----------------
-EAAAAREEERRARARV-PPTEMFR---GNSAYSAFDA-DGVPTADAEGEPLSKSMCKKL
RKQWEQQKKAYDAWVAVSGEERGM---
>gi|110757574|ref|XP_394641.3|	Apis mellifera
------------------------------------------------------------
-------------------------------------------MA---------------
----------------------------------------KRIQPS-----WVPP----Q
RKNS-SVLKLYNSLTRNKEIFVPQF----GNH-ILW---------------YSCG---PT
VYDASHM------------------GHA-------------------RSYMSFDIIRRVL
SDYFGYDILYVMNITDIDDKIIKRARQNYLYEKYIKENHT------LDKILDDAKNVMYI
FEDTVKSTTDTD-----KKYILQNIL----------CNVEKAIENLEDAVKLKD-EDKMK
EF---------------QELLLKEVRDPLAEWLDKEKGAMVT--EHSIFTKLSQYWEQEF
HK--DMDSLNVLRPNVLTRVSEYIPEIIEFIKKIIENGIAYES------NGSVYFDVSTF
NKQDKHYYAKLVPEAYGDT-----LSLQEGEGDLSTLE--I-SEKRSPIDFALWKCSKEG
EPWWESPWGKG-RPGWHIECSVMASI-ICGESLDIHTGGVDLKFPHHDNEIAQAEAYFNN
-----SNWVRYFLHSGHLTISGC--KMSKSLKNFITIQDALKK--YSARQLRLAFLLHSW
KDTLDYSDNTMHMAIQYEKFLN-----------------------EFFLNVKCKIRSLGS
ETNIN---TFIKWTNFEIELNEKFYNARDFVHNALCDNIDTRSALDAIRDLVTHCNIYM-
---KE-------IKQPN-TLLLRDVAVYITKMFTIFG----TISYSHDAIGFPI----DS
NIV------KL-------------------------------NVEQAVMPYLEILANFRE
KVR--NHAKTLK-----------AST---------ILEECDTLRDDILPNIGVRLEDSNN
-----EICKIKLVNR---EDLLKEKESKKQMELEKMLEKEKKK-----------------
-AEIAAAAVMKEAQRKI-PPSEIFKL--ERDKYSRFDS-NGLPTHDINGKEISKGQIKKL
QKLQQAQEKRYNEYLASI---------
>gi|74183161|dbj|BAE22530.1|	Mus musculus
------------------------------------------------------------
-----MAGSSAEQAADYRSILSISDEAARVQALDQHLSTRSYIQGYSLSQADVDVFRQLS
APPADSRLFHVARWFRHIEALLGGPQGRDEPCRLQAS-KGRRVQPQ-----WSPP----A
GTEP-CRLRLYNSLTRNKDVFIPQD----GKK-VTW---------------YCCG---PT
VYDASHM------------------GHA-------------------RSYISFDILRRVL
RDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQYREQKPP------ATQLLKDVRDAMKP
FSVKLSETTDPD-----KRQMLERIQ----------NSVKLATEPLEQAVRSSLSGEEVD
SK---------------VQVLLEEAKDLLSDWLDSTGGSEVT--DNSIFSKLPKFWEEEF
HK--DMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYAS------NGSVYFDTAKF
AASEKHSYGKLVPEAVGDQ-----KALQEGEGDLSISADRL-SEKRSPNDFALWKASKPG
EPSWPCPWGKG-RPGWHIECSAMAGT-LLGASMDIHGGGFDLRFPHHDNELAQSEAYFEN
-----DCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKK--HSARQLRLAFLMHSW
KDTLDYSSNTMESALQYEKFMN-----------------------EFFLNVKDILRAPVD
ITG-----QFEKWEAEEVELNKNFYGKKTAVHEALCDNIDTRTVMEEMRALVSQCNLYMA
ARKAE-------RRRPN-RALLENIAMYLTHMLKIFG----AIEEE-SPLGFPV----GG
PGT------NL-------------------------------NLESTVMPYLQVLSEFRE
GVR--KIAREKK-----------VLE---------VLQLSYALRDDILPELGVRFEDHEG
-----LPTVVKLVDR---DTLLKEKEGKKRAEEEKRRKKEEAA-----------------
-RKKQEQEAAKLAKMKI-PPSEMFLS--EVNKYSKFDE-NGLPTHDTEGKELSKGQAKKL
KKLFEAQEKLYKEYLQMLQNGSLQ---
