>gi_149602254_ref_XP_001520008.1_	Ornithorhynchus
MPAALGPLILAPPE--QEGP
PMGRLEEEAPRWSQEASPRG
GPP---APEVSHQRFRQFRY
QDSAGPHEALGRLRELCRQW
LRPDRHTKEQILELLVLEQF
LTVLPADIQTWVREQNPESG
---------EEAVTLVEDLE
REPKKLMRWVTVQVQGREVL
LETMDSSSFPLDPEE-PQPE
GLSPERGPPGPPP-------
----GPQDQLSRSIKEEEPD
ILQESVLPEERSTRDREAAS
SLLPVGAQRRKVRGARPPPP
APASRAGVGGRRKRIRWSVE
QWEQPDPAPGALFGDVVWED
AGTAAALVPK----------
--------------------
---------------PDPVV
AMGRGDEPWGPDL----HEP
EERGGLRGT-GTAADAAP-A
DPGLAATLSAAARGGVPE--
------CIRRWLGARKEPPR
--------------------
LEVSPPSWAVKSHRPPALR-
--------------GRPSPQ
TVAKRVPKPDPVVAMGRGDE
PWGPDLHEPEERGGLRGTGT
GEEVEMRKPSGTPASRPRSL
PSIPPSPRALRLLHARAPIG
L-HRLPGGQRTAPP-PP---
--------------------
--------WIDRSTGSIDRA
PTACRALTRRSGPC----VR
ASRGCSSSGPRARGDPER--
-----------SGARGVPEC
I---RRWLGARKEPPRLETG
PP---SRRSRRSADTADRGT
GKSSASPRVTSRP-RTRRAR
PLAGRPVVGHRAFSVFLQDR
IGTTAKEICSFMR-------
--GGIAERG-----------
--GVRVGHRIIEINGQSVVA
TPHEKIVHILSNAVGEDGPP
PAAPRGEG-EPPPRPRDPP-
--------------------
----------AAAPGGEGAH
RCPD-CGKGFGQKSQLVRHQ
RSHSGEKPYGCPSCGKGF--
MWKTHLRDHQRTHTGEQPYE
CPVCGKGFGYSSSVTVHLRI
HTGEKPYKCAGCGKGYGDRS
VLRYHERTHLREKPYKCGDC
GKGFNDRSALRYHQRTHTGE
KPYECPGC-----GKGFSMS
SNFYRHLRTHTGEKPYRCGD
CGKSFGDRSVLYSHRRTHTG
EKPYKCPGCGKAFSRSSNQK
AHTRTPRGANPYKCPICGRG
FRWSSHLYIHQRTHTGEKPY
KCPICGKGFSRSSSLNRHQS
VHTGEKPFRCPSCGKSFSRR
AHLYAHQRTHTGEKPYKCDE
CGKGFSERANMYRHQTVHTG
EKPYKCPICGKGFTQSTSVA
VHRKI-HMVGK--------A
LL---PGP--FPILSK----
-----
>gi_223648482_gb_ACN10999.1_	Salmo
-----MTRAPIHKMEADNCP
AGNKVEQTVSSPQQENTACG
G-P---AVGDPDSQSQSP--
-KAASKAS------------
--HPESEDLDSFN-------
---------------LIEPP
---------P--------LD
WRSDDSSEAGSVEEMD----
-----DPSFPPSLVPVDSPE
DVLGESLSAGDG--------
------VGESLPLLDTSDTV
AFP----------VVVSQEE
LINFAPEDRTPTEQVLDPCE
K-------------------
-------------ERV-VEE
EKKVEVWRPG----------
--------------------
---------------DEDHT
RIHHLLNRLQVIRESPLPRD
STSDPTSSAFSESSDFDPPF
PSLLTDVSPFLPEQNLNQAS
G---------LLFSESQQRD
--------------------
LLGL-LECTEIGVPQPSP--
--------------------
------SDTQVPHYVA----
--------------------
-----------RREEMDAVV
-SVSYNQE------DGERFW
D-HFGNSGRLRHRDD-----
--------------------
--------SVDSISKDEVPE
PVW-MKLGE-EAPEEVNDAE
NRERGTEDHPAYKDVPGP--
-----------CDPDDLLDG
VIFGAKYLGSTQLKS--DKN
PS--TNARMKQAQEAVDRIK
------------A-PEGESQ
PMT--------EVDLFISTQ
---RIKVLSADTQ-------
--EAMMDH------------
--PLQMISYIADI-GSIVVL
MARRKP--------------
---AVGRKGQEGNPT-----
--------------------
-----------GANSPGPQK
KCCMICHVFNSDDAQVI---
----------AQAIGQAFGV
AYQQFLHAN-----GIKASE
--------------------
-LKPSEYSDYLGTQELYNGD
LVHFS----------DSDNI
REVSISK---------APGE
IV----GVAVVESGWGSILP
TVV--VANLLHGGPAERCGA
LSI--GDR-IMSVNSTSLVG
LPITTCQSIIRDLKNQAEVK
LSI-----------------
--------------------
--------------------
-------VHCPPVTMAIIKR
PDP-KFQLGFSVEDGIICSL
MRGGIAERGG------IRVG
HRIIE--INGQSVVATPHEK
IIHILTNAVGE--------I
HLKTMPAST-YRLLTGQDT-
-PVFL
>NP_004877.1
---------MDFPT--ISRS
PSGPPAMDLE----------
------GPRDILVPSEDL--
--TPDSQW------------
--------------------
---------------DPMPG
--------------GPGSLS
RMELDESSLQEL--------
-----VQQF----EALPGDL
VGPS------PG--------
------------GAPCPLHI
ATGHGLAS-----QEIADAH
GLLSAEAGRDDLLGLLHCEE
C-------------------
--------------------
--------------------
--------------------
--------------------
-------------------P
PSQTGPEEPL------EP-A
PRLLQ--PPEDPDEDSDS--
--------------------
--------------------
-----PEW------------
--------------VEGASA
--------------------
--------------------
------------EQEGSRSS
-SSSPEPW------------
------------LETVPL--
--------------------
--------VTPEEPPAGAQS
PET-----------------
-----LASYPAPQEVPGP--
-----------CDHEDLLDG
VIFGARYLGSTQLVS--ERN
PP--TSTRMAQAREAMDRVK
------------A-PDGETQ
PMT--------EVDLFVSTK
---RIKVLTADSQ-------
--EAMMDH------------
--ALHTISYTADI-GCVLVL
MARRRL--------------
---ARRPA------------
--------------------
-------------PQDHGRR
LYKMLCHVFYAEDAQLI---
----------AQAIGQAFAA
AYSQFLRES-----GIDPSQ
--------------------
-VGVHPSPGACHL---HNGD
LDHFS----------NSDNC
REVHLEK---------RRGE
GL----GVALVESGWGSLLP
TAV--IANLLHGGPAERSGA
LSI--GDR-LTAINGTSLVG
LPLAACQAAVRETKSQTSVT
LSI-----------------
--------------------
--------------------
-------VHCPPVTTAIIHR
PHA-REQLGFCVEDGIICSL
LRGGIAERGG------IRVG
HRIIE--INGQSVVATPHAR
IIELLTEAYGE--------V
HIKTMPAAT-YRLLTGQEQ-
-PVYL
>gi_189524066_ref_XP_693879.3_	Danio
---------MSHREEPEEAG
LRGPPPHRSKQPNGTPLE-G
GRPRWRPCQLHNPDAESQ--
-GQHHHHYHHQAHQHASGSS
RAPPRHRRRHVPG-------
------------QAQRRRPE
SGDSEARAGQQPKPGASKHH
RSGERLYQHRYRQQHKDEEQ
HVKTPPKEQ--ASEPLLSPD
DSSQDLLTPSPQ--------
------DEPVTDELDESSPD
LSHSSDTQIN---RDPEQEQ
AESSVDQPEENVHREEFKNP
C------------------E
EELVKVNEVEDLSTQI-PEE
DYVPPKIASKSRPESKRTSP
LRVDVPPFATSPHQIINKPF
FQSPRSFPESLRRYNSDPKS
YPTFFNNNYACTRNDKEFDS
PRSHDEGDLSDSEAYTDS-Y
PES----HPKDTETDLNPAF
EEPQAYEMNYSMSMDECDDQ
QDLEEEPNPHSAVGSRLHHY
DEQS-GDEAESFGRSRAHLR
KTSSSTSLPLEVHPQDDETS
EMTQNSTDLQEEVEDV----
---PEKQDQITESCKATGDA
VSLAIRDIKEAIEEVKTKTV
-RSPYMPD-----KITEPVW
VMRQDVSPVEESHPQIHSYP
QSPCQISQSSP---------
---QYAAPIQDAEPPLGAES
SGV-LHQDQDQELCPNVPSE
EQRKSLASFPTYVDVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--ERT
PT--KSARMQQAQEAMSRVR
-TAQAQAKIRNKG-TESGPP
SCT--------EVDLFISTQ
---RIKVLSAYTQ-------
--DTMMDH------------
--PLRTISYIADI-GNMVVL
MARRKM--------------
---IRSQSAQENLDTAETQ-
--------------------
----------HTNPARDDRR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GIDPED
--------------------
-LSQREYSDLLNTQDMYNDD
LIHFS----------KSENC
RDVYIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IASLMHGGPAAKSGR
LNI--GDQ-IMTVNGTSLVG
LPLSTCQSIIKGLKSQSRIK
MNI-----------------
--------------------
--------------------
-------VRCPPVTMVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_109111730_ref_XP_001093689.1_	Macaca
---------MNH----LEGS
AEVEVTDEAA---------G
G-E---VNESVEADLEHP--
-DVEEEQQ--QQPPQQQHYA
GRHQRGGALEDLR-------
----------------AQLG
---------QEEEERGECLE
RSASTESGFHNHTDTAEGDV
IAAA-RDGY--DAERAQDPE
DESAYAVQYRPE--------
------AEEYTEQAEAEHAE
ATHRPALPNHLHFHSLEHEE
AMNAAYSGYVYTHRLFHRGE
D------------------E
PYAEPYADYGGLQEHV-YEE
IGDAPELDAR----------
--------------------
--------DGLRLYEQEPDE
AAAYRQEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PEAEQDLERPPTP--
--------------TGGRPD
-----SPGLQAPAGQQ--RA
TGPAGGGEAGQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPTRDCDDQRPMDG
GSP-----------------
--------SPGSSSPLGAES
SGTPLHPSD---PAEASTNK
ESRKSLASFPTYVEVPSM--
-----------CKPHPLPKE
MCLAP-WLPTVQLLG--DKA
PSLLKNTKINQAEVAVSQDH
-MAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QENVEA-----
--------------------
-----------SHPSQDGKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVFIEK---------QKGE
IL----GVVIVESGWGSLAP
PIIWQLRNLSCAGPVDRSGR
PEH--LPL-LMGTMGPAAYG
RPGSFADSLVAGLKNQSRVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_149062601_gb_EDM13024.1_	Rattus
---------MNH----LEGS
AEVEVADEAP---------G
G-E---VNESVEADLEHP--
-EVEEEQQ--------PQPS
PPPPAGHAPEDHR-------
--------AHPAPPPPPPPQ
---------EEEEERGECLA
RSASTESGFHNHTDTAEGDV
LAAA-RDGY--EAERAQDAD
DESAYAVQYRPE--------
------AEEYTEQAEAEHAE
AAQRRALPNHLHFHSLEHEE
AMNAAYSGYVYTHRLFHRAE
D------------------E
PYAEPYADYGGLQEHV-YEE
IGDAPELEAR----------
--------------------
--------DGLRLYERERDE
AAAYRQEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PEAEQDLERAPTP--
--------------GGGHPD
-----SPGLPAPAGQQ-QRV
VGTPGGSEVGQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPTRDCDDQRPVDG
DSP-----------------
--------SPGSSSPLGAES
SITPLHPGD---PTEASTNK
ESRKSLASFPTYVEVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--DKT
PS--KNVRMMQAQEAVSRIK
-TAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--EPMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QENVEA-----
--------------------
-----------SHPSQDAKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVFIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IANMMHGGPAEKSGK
LNI--GDQ-IMSINGTSLVG
LPLSTCQSIIKGLKNQSRVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_74188559_dbj_BAE28031.1_	Mus
---------MNH----LEGS
AEVEVADEAP---------G
G-E---VNESVEADLEHP--
-EVVEGQQ--------PSPS
PPPPAGHEPEDHR-------
----------------GHPA
PPPPPPPQEEEEEERGECLA
RSASTESGFHNHTDTAEGDV
LAAA-RDGY--EAERAQDAD
DESAYAVQYRPE--------
------AEEYTEQAEAEHVE
AAQRRALPNHLHFHSLEHEE
AMNAAYSGYVYTHRLFHRAE
D------------------E
PYAEPYADYGGLQEHV-YEE
IGDAPELEAR----------
--------------------
--------DGLRLYERERDE
AAAYRQEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PEAEQDLERAPTP--
--------------GGGHPD
-----SPGLPAPAGQQ-QRV
VGTPGGSEVGQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPTRDCDDQRPVDG
DSP-----------------
--------SPGSSSPLGAES
SSIPLHPGD---PTEASTNK
ESRKSLVSFPTYVEVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--DKT
PS--KNVRMMQAQEAVSRIK
QTAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--EPMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QENVEA-----
--------------------
-----------SHPSQDGKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVFIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IANMMHGGPAEKSGK
LNI--GDQ-IMSINGTSLVG
LPLSTCQSIIKGLKNQSRVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_119900375_ref_XP_593610.3_	Bos
---------MNH----LEGA
AEVEVTDEAA---------G
G-E---VNESVEADLEHP--
-EVEEEQQ------QQQHYA
GRPRRRRAVEDPR-------
----------------AQPG
----QQQQQQEEDEHGECLA
RSASTESGFHNHTDTAEGDV
IAAA-RDGY--DAERTQDPD
DESAYAVQYRPE--------
------AEEYTEQAEAEHAE
ATHRRALPNHLHFHSLEHEE
AMNAAYSGYVYTHRLFHRGE
D------------------E
PYAEPYADYGGLQEHV-YEE
IGDAPELDAR----------
--------------------
--------DGLRLYEQERDE
AAAYRQEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PEAEQDLERAPTP--
--------------GGGRPD
-----SPGLQAPAGPQ----
--RAAGGEAVQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPTRDCDDQRPVDG
DSP-----------------
--------SPGSSSPLGAES
LSTPLHPGD---PAEASTNK
ESRKSLASFPTYVEVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--DKT
PS--KNVRMMQAQEAVSRIK
-MAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QENVEA-----
--------------------
-----------SHPSQDGKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVFIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IANMMHGGPAEKSGK
LNI--GDQ-IMSINGTSLVG
LPLSTCQSIIKGLKNQARVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_114624952_ref_XP_528317.2_	Pan
---------MNH----LEGS
AEVEVTDEAA---------G
G-E---VNESVEADLEHP--
-EVEEEQQ---QPPQQQHYV
GRHQRGRALEDLR-------
----------------AQLG
---------QEEEERGECLA
RSASTESGFHNHTDTAEGDV
IAAA-RDGY--DAERAQDPE
DESAYAVQYRPE--------
------AEEYTEQAEAEHAE
ATHRRALPNHLHFHSLEHEE
AMNAAYSGYVYTHRLFHRGE
D------------------E
PYAEPYADYGGLQEHV-YEE
IGDAPELDAR----------
--------------------
--------DGLRLYEQERDE
AAAYRQEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PEAEQDLERPPTP--
--------------AGGRPD
-----SPGLQAPAGQQ--RA
VGPAGGGEAGQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPTRDCDDQRPMDG
DSP-----------------
--------SPGSSSPLGAES
SSTSLHPSD---PVEASTNK
ESRKSLASFPTYVEVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--DKT
PS--KNVRMMQAQEAVSRIK
-MAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QENVEA-----
--------------------
-----------SHPSQDGKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVFIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IANMMHGGPAEKSGK
LNI--GDQ-IMSINGTSLVG
LPLSTCQSIIKGLKNQSRVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_22035548_ref_NP_001154.2_	Homo
---------MNH----LEGS
AEVEVTDEAA---------G
G-E---VNESVEADLEHP--
-EVEEEQQ---QPPQQQHYV
GRHQRGRALEDLR-------
----------------AQLG
---------QEEEERGECLA
RSASTESGFHNHTDTAEGDV
IAAA-RDGY--DAERAQDPE
DESAYAVQYRPE--------
------AEEYTEQAEAEHAE
ATHRRALPNHLHFHSLEHEE
AMNAAYSGYVYTHRLFHRGE
D------------------E
PYSEPYADYGGLQEHV-YEE
IGDAPELDAR----------
--------------------
--------DGLRLYEQERDE
AAAYRQEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PEAEQDLERPPTP--
--------------AGGRPD
-----SPGLQAPAGQQ--RA
VGPAGGGEAGQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPTRDCDDQRPMDG
DSP-----------------
--------SPGSSSPLGAES
SSTSLHPSD---PVEASTNK
ESRKSLASFPTYVEVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--DKT
PS--KNVRMMQAQEAVSRIK
-MAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QENVEA-----
--------------------
-----------SHPSQDGKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVFIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IANMMHGGPAEKSGK
LNI--GDQ-IMSINGTSLVG
LPLSTCQSIIKGLKNQSRVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_126334568_ref_XP_001365486.1_	Monodelphis
---------MSH----VEGP
PEVEVIDEPG---------S
G-ESGEVNESVEADLEHL--
-EVEEEQRPRQQPQPQPQHA
APYSRGPAQGERG-------
----------------PLPV
-------QGPEEEDRGGSLA
RSASTESGFHNHTDTAEGDV
IAASGEDGY--DPERGQENE
DESAYAVQYRPE--------
------AEEYTENAEAEHAE
AAHRRSLPNHLHFHSLEHEE
AMNAAYSGYVYTHRLFHRSE
D------------------E
PYAEPYADYSGLQEHV-YEE
IGDTAELDGR----------
--------------------
--------EGLRLYEQEREE
ADNYRKEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PEAEQNLDRVPSPDG
GGGGGGGGGGDGDDGGGEQG
-----NPGQIASVGPR----
PAVLAGEAGQQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPTRDCEDQRPADG
DSP-----------------
--------SPDSSSPRGAES
SSR-QHQQD--DLPESSTNK
ESRKSLASFPTYVEVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--DKT
PS--KNVRMMQAQEAVSRIK
-MAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QDNVEA-----
--------------------
-----------SHPSQDGKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVFIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IANMMHGGPAEKSGK
LNI--GDQ-IMSINGTSLVG
LPLSTCQSIIKGLKNQSRVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_224089203_ref_XP_002190319.1_	Taeniopygia
---------MNH----LVGP
PEGDISEEPA---------N
G-A---VSESVEADLEHS--
-EVEEEQR----------YA
VRYPRHNNSSHVG-------
-----------------LSG
---------QEEE---GMLA
RSASTESGFHSHTDTAEGDV
IATV-EDSY--NVERVQENE
DESAYAVQYRPE--------
------SEEYTENAEAEHGE
AIHNRTLPNHLHFHSIEHEE
AMNAAYSGYVYTHRLFHRGE
D------------------E
QYAEAYADYG-LQEHV-YEE
IGDTPDLDGR----------
--------------------
--------EGIQQYEREREE
ADNYRKEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PESEQSLEHGHALV-
--------------TGGHES
-NGQLTSGSRVTSGSG----
-------ESVQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPSRDSDDQRPLDG
DSP-----------------
--------SPDSSSPRGAES
SSR-QHQQDVCSTAEASTNK
ESRKSLASFPTYVEVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--DKT
PS--KNVRMMQAQEAVSRIK
-MAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QDNVEA-----
--------------------
-----------SHPSQDGKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVYIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IANMMHGGPAEKSGK
LNI--GDQ-IMSINGTSLVG
LPLSTCQSIIKGLKNQARVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_118104070_ref_XP_424829.2_	Gallus
---------MNH----LVGP
PDGEVSEEPA---------N
G-A---VNESVEADLEHS--
-EVEEEQR----------YA
SHYPRHTN-SSQG-------
----------------GLSG
---------QEEE---GMLA
RSASTESGFHNHTDTAEGDV
IATV-EDSY--DTERVQENE
DESAYAVQYRPE--------
------SEEYTENAEAEHGE
AIHNRTLPNHLHFHSIEHEE
AMNAAYSGYVYTHRLFHRGE
D------------------E
QYAEPYADYG-LQEHV-YEE
IGDTPDLDAR----------
--------------------
--------EGIQLYEREREE
ADNYRKEALGARLH---HYD
ERSDGESDSPEKEAEFAP-Y
PRM----DSYEQEEDIDQIV
A-----EVKQSMSSQSLDKA
--------------------
AEDM-PEAEQSLEHAHALA-
--------------GGGHES
NNSQLPPGSRVTSSSG----
-------ETVQRYSKEKRDA
ISLAIKDIKEAIEEVKTRTI
-RSPYTPD-----EPKEPIW
VMRQDISPTRDSDDQRPLDG
DSP-----------------
--------SPDSSSPRGAES
SSR-QHHQDVCSTAEPSTKK
ESRKSLASFPTYVEVPGP--
-----------CDPEDLIDG
IIFAANYLGSTQLLS--DKT
PS--KNVRMMQAQEAVSRIK
-MAQKLAKSRKKA-PEGESQ
PMT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--PLRTISYIADI-GNIVVL
MARRRM--------------
---PRSNS-QDNVEA-----
--------------------
-----------SHPSQDGKR
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDLLNTQDMYNDD
LIHFS----------KSENC
KDVYIEK---------QKGE
IL----GVVIVESGWGSILP
TVI--IANMMHGGPAEKSGK
LNI--GDQ-IMSINGTSLVG
LPLSTCQSIIKGLKNQARVK
LNI-----------------
--------------------
--------------------
-------VRCPPVTTVLIRR
PDL-RYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATPHEK
IVHILSNAVGE--------I
HMKTMPAAM-YRLLTAQEQ-
-PVYI
>gi_148228617_ref_NP_001087166.1_	Xenopus
---------MANRK--CQSA
TASIMDQRPR---------S
CPP---SPHAQDPGSEESVY
EEVIVPDF----------VN
SRISKSRHMSNT--------
--------------------
---------QEDH---DCND
NSGDGDSSSDYVNNTS----
-----DEEY--D-EGLPDEE
EGITYYIRYCPE--------
------DDSYLEGMDCNGEE
YIHHEE-------RHIETDE
CVEAVEDEWTESKTQQQHCI
D------------------R
ETEEENQ----------MNA
LGEDSSLGVH----------
--------------------
----------------DQVE
EAHFCENEEGYQD----YYS
PEANGNSLPP------SP-F
PIRKGDRDTEETEEDIDQIV
A-----EIKMSMSMSSINST
--------------------
TDTS-PEHNVTENVA-----
--------------KDIKEI
-----CEKVDSGHCAS----
--------------------
-----------RHEGRPKSL
-NIPSASK---------PAT
ELQRGYKAKARTPEERQK--
--------------------
--------WAPEQVCNSVEQ
PRK-QQRSDLNGPVDNNNVQ
EQTKKVTSFPSFVDVPGP--
-----------CEPEDLIDG
IIFAANFLGSTQLLS--ERN
PS--KNIRMMQAQEAVSRVK
-------------NSEGDSQ
TLT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--ALRTISYIADI-GNIVVL
MARRRM--------------
---PRSAS-QDCIET-----
--------------------
-----------TPGAQEGKK
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDIINTQEMYNDD
LIHFS----------NSANC
KELQVEK---------LKGE
IL----GVVIVESGWGSILP
TVI--LANMMNGGPAARSGK
LSI--GDQ-IMSINGTSLVG
LPLATCQGIIKGLKNQTQLK
LNI-----------------
--------------------
--------------------
-------VSCPPVTTVLIKR
PDL-KYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATAHEK
NC------------------
-----PSTIQFRRRDSHEDY
ASSNV
>gi_197098586_ref_NP_001125150.1_	Pongo
---------MAHQK--LESV
GSGMLDHRVR---------P
G-P---VPHSQEPESEDM--
-ELPLEGY------------
--VPEGLELAALR-------
---------------PESPA
---------PEEQ---ECHN
HSPDGDSSSDYVNNTSE---
-----EEDY--D-EGLPEEE
EGITYYIRYCPE--------
------DDSYLEGMDCNGEE
YLAHGA-------HPVDTDE
CQEAVEE-WTDSAGPRPHSH
E------------------A
EGSQDYPD-----GQL-PIP
EDEPSVLEAH----------
--------------------
----------------DQEE
DGHYCASKEGYQD----YYP
EEANGNTSA-------SP-Y
RLRRGDRDLEDQEEDIDQIV
A-----EIKMSLSMTSITSA
--------------------
SEAS-PEH----GPEPGP--
--------------GDSAEA
-----CPPIKASCSPS----
--------------------
-----------RHEARPKSL
-NLPPEAK-----HPGDP--
--QRGFKPKTRTPEERPK--
--------------------
--------WPHEQVCNGLEQ
PRK-QQRSDLNGPVDNNNIP
ETKK-VASFPSFVAVPGP--
-----------CEPEDLIDG
IIFAANYLGSTQLLS--ERN
PS--KNIRMMQAQEAVSRVK
-RMQKAAKIKKKANSEGDAQ
TLT--------EVDLFISAQ
---RIKVLNADTQ-------
--ETMMDH------------
--ALRTISYIADI-GNIVVL
MARRRM--------------
---PRSAS-QDCIET-----
--------------------
-----------TPGAQEGKK
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDIINTQEMYNDD
LIHFS----------NSENC
KELQLEK---------HKGE
IL----GVVVVESGWGSILP
TVI--LANMMNGGPAARSGK
LSI--GDQ-IMSINGTSLVG
LPLATCQGIIKGLKNQTQVK
LNI-----------------
--------------------
--------------------
-------VSCPPVTTVLIKR
PDL-KYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATAHEK
IVQALSNSVGE--------I
HMKTMPAAM-FRLLTGQET-
-PLYI
>NP_005494.2
---------MAHRK--LESV
GSGMLDHRVR---------P
G-P---VPHSQEPESEDM--
-ELPLEGY------------
--VPEGLELAALR-------
---------------PESPA
---------PEEQ---ECHN
HSPDGDSSSDYVNNTSE---
-----EEDY--D-EGLPEEE
EGITYYIRYCPE--------
------DDSYLEGMDCNGEE
YLAHSA-------HPVDTDE
CQEAVEE-WTDSAGPHPHGH
E------------------A
EGSQDYPD-----GQL-PIP
EDEPSVLEAH----------
--------------------
----------------DQEE
DGHYCASKEGYQD----YYP
EEANGNTGA-------SP-Y
RLRRGDGDLEDQEEDIDQIV
A-----EIKMSLSMTSITSA
--------------------
SEAS-PEH----GPEPGP--
--------------EDSVEA
-----CPPIKASCSPS----
--------------------
-----------RHEARPKSL
-NLLPEAK-----HPGDP--
--QRGFKPKTRTPEERLK--
--------------------
--------WPHEQVCNGLEQ
PRK-QQRSDLNGPVDNNNIP
ETKK-VASFPSFVAVPGP--
-----------CEPEDLIDG
IIFAANYLGSTQLLS--ERN
PS--KNIRMMQAQEAVSRVK
-RMQKAAKIKKKANSEGDAQ
TLT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--ALRTISYIADI-GNIVVL
MARRRM--------------
---PRSAS-QDCIET-----
--------------------
-----------TPGAQEGKK
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDIINTQEMYNDD
LIHFS----------NSENC
KELQLEK---------HKGE
IL----GVVVVESGWGSILP
TVI--LANMMNGGPAARSGK
LSI--GDQ-IMSINGTSLVG
LPLATCQGIIKGLKNQTQVK
LNI-----------------
--------------------
--------------------
-------VSCPPVTTVLIKR
PDL-KYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATAHEK
IVQALSNSVGE--------I
HMKTMPAAM-FRLLTGQET-
-PLYI
>gi_194206361_ref_XP_001917083.1_	Equus
---------MANRK--RQST
VSSMLDHRAR---------P
G-P---VPQGQEPESEDV--
-ELPLEEY------------
--VPKGLELAALR-------
---------------PESPL
---------PVEQ---GCHD
HSPDGDSSSDYVNNTSE---
-----EEDY--D-EGLPEEE
EGITYYIRYCP---------
------DDSYLEGMDCNGR-
YLAHGT-------RHLETDE
CQEAVEE-WTDSAGPHPHGH
G------------------D
EGSPDYRD-----SHL-PIP
EDEASVLEAQ----------
--------------------
----------------DQEE
GVHYCPSEEGYQD----YYP
TEANGNAGST------SP-Y
RPRRGDGDLEDQEEDIDQIV
A-----EIKMSLSMTSITSA
--------------------
GEAS-PEHGLVRGPEPGP--
--------------GDSTEA
-----CLPGEASHGPS----
--------------------
-----------RHEGRPKSL
-NLPSETK-----HPGDP--
--QRGFKTKTRTPEERPK--
--------------------
--------WPQEEVCNGLEQ
PRK-QQRSDLNGPVDNNNIP
ETKK-VASFPSFVAVPGP--
-----------CEPEDLIDG
IIFAANYLGSTQLLS--ERN
PS--KNIRMMQAQEAVSRVK
-RMQKAAKIKKKANSEGDAQ
TLT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--ALRTISYIADI-GNIVVL
MARRRM--------------
---PRSAS-QDCIET-----
--------------------
-----------TPGAQEGKK
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDIINTQEMYNDD
LIHFS----------NSENC
KELQLEK---------HKGE
IL----GVVVVESGWGSILP
TVI--LANMMNGGPAARSGK
LSI--GDQ-IMSINGTSLVG
LPLATCQGIIKGLKNQTQVK
LNI-----------------
--------------------
--------------------
-------VSCPPVTTVLIKR
PDL-KYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATAHEK
IVQALSNSVGE--------I
HMKTMPAAM-FRLLTGQET-
-PLYI
>gi_73951027_ref_XP_848698.1_	Canis
---------MASRK--RQST
ASGTLEHRAR---------P
G-P---APHGPEPGGGEA--
-ELPPEEY------------
--VPERLELAALR-------
---------------PESPA
---------PPDQ---GCHD
HSPDGDSSSDYVNNTSE---
-----EEDY--D-EGLPEEE
EGITYYIRYCPE--------
------DDSYLEGMDCNGEG
YLAHGP-------RHLETDE
CQEAVEE-WTDSAGPHPHGP
A------------------D
GGSPDYRD-----GHL-PVP
EDEASALEAQ----------
--------------------
----------------DQEE
GVHYCPSEEGYQD----YYP
TEANGNAGGA------SP-Y
RPRRGDGDLEDQEEDIDQIV
A-----EIKMSLSMTSITSA
--------------------
GEAS-PEHTLVRGPEPGP--
--------------GGSTET
-----CPPCEASHGPS----
--------------------
-----------RHEGRPKSL
-NLPPEAK-----HSGDP--
--QRGFKTKSRTPEERAK--
--------------------
--------WPQEQVCNGLEQ
PRK-QQRSDLNGPVDNNNIP
ETKK-VASFPSFVAVPGP--
-----------CEPEDLIDG
IIFAANYLGSTQLLS--ERN
PS--KNIRMMQAQEAVSRVK
-RMQKAAKIKKKANSEGDAQ
TLT--------EVDLFISTQ
---RIKVLNADTQ-------
--ETMMDH------------
--ALRTISYIADI-GNIVVL
MARRRM--------------
---PRSAS-QDCIET-----
--------------------
-----------TPGAQEGKK
QYKMICHVFESEDAQLI---
----------AQSIGQAFSV
AYQEFLRAN-----GINPED
--------------------
-LSQKEYSDIINTQEMYNDD
LIHFS----------NSENC
KELQLEK---------HKGE
IL----GVVVVESGWGSILP
TVI--LANMMNGGPAARSGK
LSI--GDQ-IMSINGTSLVG
LPLATCQGIIKGLKNQTQVK
LNI-----------------
--------------------
--------------------
-------VSCPPVTTVLIKR
PDL-KYQLGFSVQNGIICSL
MRGGIAERGG------VRVG
HRIIE--INGQSVVATAHEK
IVQALSNSVGE--------I
HMKTMPAAM-FRLLTGQET-
-PLYI
