>gi|3892185|gb|AAC78302.1|	Schistosoma japonicum
-----------------LEF--------------LFFAFATCS-----------------
-------------------E----------------------------------------
------------------------------------------------------------
------------------------------VLELTKDNFHSQLKS---IPVCLVKFY---
--APWCGHCKSLAPEYKSAADIISKKTANLKLAEVDCTAHA-DICSEFGVNGYP-TLKIF
RDGI---------------------------------------------FDSEYNGPRNA
DGIANYMISRAGPVSKEIS-----AFKDVEDSLSD--DKPSVVAFIKSSSDPLMKTFMTL
AKSMIDNAVFLHSHNN-IYENSGENE---LRLYLPKRLRTKLEPDFSIYS---GE--MEV
DDIKKWIRKDGHGLVGYRSPDDS---FYFVDSNLVVIYNNESINTYPSGVKYLRNRILKT
LKNHPDKFKDLKFAYSFTGD-------------FSYELSDYEINADQLPAVRISS--KDG
KKYRL---DKYSPE--SFLEFLNKFQNGLLTPHLKSEPIPTS-DSSVVKKLVALNFNDIV
ND-----------------------EEKDVMVVFHAPWCGHCKNLMPKYEEAASKLKNEP
N------LVLAAMDATANDVPPP--YEVTGFPTIYFVPKGKKSSPMLYQGG-RDTSDIIK
FLAREATEELSGYDRSGNT-----------------------------------------
----------------------KKSDL---------------------------------
--------------------------------
>gi|21703694|gb|AAA49054.2|	Gallus gallus
-------------TPSRPSRLSAAMAVVRVRAIVALLCLVAAL-----------------
---------GLAQPLEEEDG----------------------------------------
------------------------------------------------------------
------------------------------VLVLRAANFEQALAA---HRHLLVEFY---
--APWCGHCKALAPEYAKAAAQLKAEGSEIRLAKVDATEEA-ELAQQFGVRGYP-TIKFF
RNGDK-------------------------------------------AAPREYTAGREA
DDIVSWLKKRTGPAATTLT-----DAAAAETLVDS--SEVVVIGFFKDVTSDAAKEFLLA
AESV-DDIPFGISSSADVFSKYQLSQDG-VVLFK------KFDEGRNNFE---GD--LTK
DNLLNFIKSNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYEGKLDNFK----TA
AGNFKGKI-LFIFIDSDHSD-------------NQRILEFFGLKKEECPAVRLITLEEEM
TKYKPES-DDLTAD--KIKEFCNKFLEGKIKPHLMSQDLPEDWDKQPVKVLVGKNFEEVA
FD-----------------------ENKNVFVEFYAPWCGHCKQLAPIWDKLGETYRDHE
N------IVIAKMDSTANEVEA---VKIHSFPTLKFFPAGSGRNVIDYNGE-RTLEGFKK
FLESGGQDGAAADDDLEDLETDEETDLEEGDDDEQKI-----------------------
----------------------QKDEL---------------------------------
--------------------------------
>gi|125978277|ref|XP_001353171.	Drosophila pseudoobscura
-----------------MKF---------------LICTLLAA-----------------
------AFYVAAAEVKVEEG----------------------------------------
------------------------------------------------------------
------------------------------VLIATVDNFKQLVAD---NEFVLVEFY---
--APWCGHCKALAPEYAKAAQQLAEKDSPIKLAKVDATVEG-ELAEQYQVRGYP-TLKFF
RSGA----------------------------------------------PVEYSGGRQA
ADIISWVTKKTGPPAKDLT-----SVADAEQFLKD--NEIAIIGFFKDTDSEEAKTFTKA
ANAL-DSFVFGVSSNADIIAKYEAKDNG-VILFK------PFDDKKSVFE---GE--LTE
ETLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSKEAGHIEAHVDPLK----EI
AKKYRDDI-LFVTISSDEED-------------HTRIFEFFGMNKEEVPTIRLIKLEEDM
AKYKPES-NDLSAE--TIEAFLKKFLDGKLKQHLLSQDLPEDWDKQPVKVLVSSNFESVA
LD-----------------------KSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNT
D------IVIAKMDSTANELEN---IKISSFPTIKYFRKDDNK-VIDYNLD-RTLDDFIK
FLDANGEVADAEPAEETEEEEEAP------------------------------------
----------------------KKDEL---------------------------------
--------------------------------
>gi|86198316|ref|NP_033917.2|	Mus musculus
-----------------MKLR-------------KAWLLVLLL-ALTQLLAAASAGDAHE
DTSDTENATEEEEEEEEEDD-----DDLEVKEENGVWVLNDGNFDNFVADKDTVLLEFYA
PWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLASKFDVSGYPTIKILKKGQA
VDYDGSRTQEEIVAKVREVSQPDWTPPPEVTLSLTKDNFDDVVNN---ADIILVEFY---
--APWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQT-DLAKRFDVSGYP-TLKIF
RKGR----------------------------------------------PFDYNGPREK
YGIVDYMIEQSGPPSKEIL-----TLKQVQEFLKDG-DDVVIIGLFQGDGDPAYLQYQDA
ANNLREDYKFHHTFSPEIAKFLKVSLGK-LVLTHPEKFQSKYEPRFHVMDVQ-GS--TEA
SAIKDYVVKHALPLVGHRKTSNDAKRY-SKRPLVVVYYSVDFSFDYRAATQFWRNKVLEV
AKDFP----EYTFAIADEED-------------YATEVKDLGL-SESGEDVNAAILDESG
KKFAMEP-EEFDSD--TLREFVTAFKKGKLKPVIKSQPVPKN-NKGPVKVVVGKTFDAIV
MD-----------------------PKKDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQK
D------LVIAKMDATANDITNDQ-YKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSK
FIDEHATKRSR-------------------------------------------------
----------------------TKEEL---------------------------------
--------------------------------
>gi|729434|sp|P38658|ERP60_SCHM	Schistosoma mansoni
-----------------MRW--------------LLSCLFLVA-----------------
--------------FASCSK----------------------------------------
------------------------------------------------------------
------------------------------VLELTKDNFHSELKS---IPVALVKFY---
--APWCGHCKKLAPEFTSAAQIISGKTNDVKLVKVDCTTQE-SICSEFGVSGYP-TLKIF
RNGD---------------------------------------------LDGEYNGPRNA
NGIANYMISRAGPVSKEVS-----TVSDVENVLSD--DKPTVFAFVKSSSDPLIKTFMAL
AKSMVDDAVFCHSHNNLFV---TPSDNE-LRVYLPKRLRTKFEDDFAVYK---GE--LES
NNIKDWIRKHGQGLVGYRSPSNT---FYFENSDLVVLYNNQSIDSYPSGVKYLRNRVLKT
LKDNPQKFKNLVFAYSFADD-------------FSYEISDYGIEADKLPAVVIQSKDKK-
--YKL---EKFSLD--AFSDFLNKFEDGLLTPHVKSEPLPTD-DSSAVKKLVALNFDEIV
NN-----------------------EEKDVMVVFHAGWCGHCKNLMPKYEEAASKVKNEP
N------LVLAAMDATANDVPSP--YQVRGFPTIYFVPKGKKSSPVSYEGG-RDTNDIIK
YLAREATEELIGYDRSGNP-----------------------------------------
----------------------KKSEL---------------------------------
--------------------------------
>gi|70989789|ref|XP_749744.1|	Aspergillus fumigatus
-----------------MRSF-------------APLVLSLLG-----------------
----ASAVASADATADTTSD----------------------------------------
------------------------------------------------------------
------------------------------VVSLTKDSFKDFMKE---HDLVLAEFY---
--APWCGHCKALAPKYEEAATELKGK--NIPLVKVDCTEEE-DLCKENGVEGYP-TLKIF
RGPD---------------------------------------------SSKPYQGARQA
DSIVSYMIKQSLPAVSTV------TEENLEEIKTM--DKIVVIGYFASDDKAANDVFTSF
AESQRDNYLFAATSDSAIAKAEGVKQPS-IVLYK------DFDEKKAVYD---GA--IEQ
EAILSWVKTASTPLVGEIGPETYSSYITAGIP--LAYIFAETKEERDQYAEDFK----PV
AEKHKGAI-NIATIDAKM---------------FGAHAGNLNLDPQTFPAFAIQDPEKNA
K-YPYDQSREFNAK--EIGKFIQDVLDGKVEPSIKSEPIPET-QEGPVTVVVAHSYQDIV
IN-----------------------NDKDVLLEFYAPWCGHCKALAPKYEELAALYAGDF
K---DK-VTIAKIDATANDVPD----SITGFPTIKLYPAGAKDSPVEYSGS-RTVEDLAN
FIKENGKYKVDALVAASEKVEEGPDVTASPSATSTEAEAPAATGDE--------------
--------------------KGDHDEL---------------------------------
--------------------------------
>gi|156553206|ref|XP_001599732.	Nasonia vitripennis
---------------MVGKYL-------------ALFGLALVA-----------------
----------STGTWAAEED----------------------------------------
------------------------------------------------------------
------------------------------VFEWGDGDFAEELRR---HDNTLVMFY---
--APWCGHCKRLKPEYAKAAELLRGSDPPITLAKVDCTEAGKDTCNKYSVSGYP-TLKIF
AKDE---------------------------------------------LVNDYNGPREA
AGIAKYMRGQVGPASKELK-----TLAAFEEFLNS--DEISVVGFFEKDDSPLSAAFHNV
AKKLREKVRFGHTIAKEVLEKEGLENN--IVIFRPKVLQNKFEPSKQVYE---GG--DSI
SEVSAFIKQNYYGLVGVRTRDNAGEF---KNPLIVAYYAVDYVKN-PKGTNYWRNRIMKV
AKDFAKEY-DYTFAISSKDE-------------FQHELNEFGIDFVKGDKPVILARDERN
QKFALQ--EEFSLE--AFEIFLNDLQAGSLEPYQKSEPIPED-NSGSVKVAVAKNFDEVV
TN-----------------------NGKDTLIEFYAPWCGHCKKLALIFDELGDKLV-DE
D------VEIVKFDATANDVPQP--YEVRGFPTLFWVPKDSKDSPVKYEGG-RDLDDFVK
YIAKHATNPLKGYDRSGKPTKA--------------------------------------
----------------------PQDEL---------------------------------
--------------------------------
>gi|66546657|ref|XP_623282.1|	Apis mellifera
-----------------MLF--------------KYFNFLFLV-----------------
----------FASVLAEEKD----------------------------------------
------------------------------------------------------------
------------------------------VVELTDETFSHELER---LENTLVMFY---
--APWCGHCKRLKPEYAKAAEMLLDNDPSITLAKVDCTESGKDTCNKYSVSGYP-TLKIF
SKGD---------------------------------------------FVSDYNGPREA
VGIAKYMKAQVGPASKELN-----EENCLKSFLDS--DEVSVVGFFEKEDLSLATTFHAV
SKKLKEKVRFAHTTAKSLMEKEGYKNT--IVLYRPKILQNKFEANIVKYD-------ETM
GDIQEFINKNYFGIAGVRTRDNTAEF---KNPLVVAYYAVDYIKN-PKGTNYWRNRIIKV
AKDFP----NLNFAISSKDD-------------FQHELNDFGIDFVKGDKPVILARNINN
QKFVMK--DEFSVS--TFEAFLKDMEAGVLEPYLKSEPIPED-NSGNVKIAVARNFDELV
TN-----------------------NDKDTLIEFYAPWCGHCKKLAPVYDELGEKLA-NE
D------VEIIKFDATANDVPGP--YEVRGFPTLYWAPKNSKNNPVKYEGG-RELDDFIK
YIAKHATNELKGFDRKGKSVKP--------------------------------------
----------------------KSDEL---------------------------------
--------------------------------
>gi|157107430|ref|XP_001649774.	Aedes aegypti
-----------------MRVL-------------KSLSLVLLV-AGL-------------
------ALVASDAEVKEEDG----------------------------------------
------------------------------------------------------------
------------------------------VLVLTKDNFQSVVEG---NEFVLVEFY---
--APWCGHCKALAPEYAKAAKALAEKNSNIKLGKVDATEEQ-ELSEKHGVRGYP-TLKFF
RNGT----------------------------------------------PIEYTGGREK
DTIISWLEKKTGPAAKELE-----TVAEAEEFLKE--HNVAVVGFFKDRESAECKAFLAT
ANAV-DDYPFAVTSSEDVYAKYEAKCGS-IVLFK------HFDDGKAVFD---GE--YTE
EALKKFVTAQALPLIVDFSHETAQKIFGGEIKNHLLFFISKEAGHMEKYIEAAK----EV
AKKYREKI-LFVTIDADQED-------------HQRILEFFGMKKDEVPSMRIIHLEEDM
AKYKPET-NDLAAD--KVELFVSKFFEGKIKQHLLSQEVPEDWDKNPVKVLVADKFDEVA
MD-----------------------STKDVLVEFYAPWCGHCKQLVPIYDKLGEKFADHE
S------IVIAKMDATANELEH---TKINSFPTIYLYRKGDNQ-KVEYRGE-RTLEGFVN
FLEGKSEEPEVEETEEDQKP----------------------------------------
----------------------EKDEL---------------------------------
--------------------------------
>gi|118792093|ref|XP_551775.2|	Anopheles gambiae
-----------------MRLL-------------SAFGLVLAF-----------------
-----ATVALAAEEVKTEDG----------------------------------------
------------------------------------------------------------
------------------------------VLVLTKDNFDSVIAN---NEFVLVEFY---
--APWCGHCKALAPEYAKAAKVLADKESNIKLAKVDATVEP-ELAEKYGIRGYP-TLKFF
RSGS----------------------------------------------QVDYTGGREQ
DTIVSWLEKKTGPAAKELE-----TVEAAEEFLKE--NNVAVVGFFKDRDSKEAKAFMST
AVAV-DDYPFGVTSSEEVYAKYEAKCGS-VILFK------HFDEGKAVFE---GE--ATE
EALKKFVTAQALPLIVDFSHETAQKIFGGEIKSHLLFFISKEAGHLKEFVEPAK----EV
AKKFREQI-LFVTIDADQED-------------HTRILEFFGMKKDEVPSLRIIRLEEDM
AKYKPET-NDLSAD--KILEFVQSFLDGKVKQHLLSQDLPEDWDKEPVKVLVATKFDEVA
FD-----------------------KTKDVLVEFYAPWCGHCKQLVPIYDKLGEKYKDSD
S------VVIAKIDATANELEH---TKISSFPTIYLYRKGDNE-KVEFKGE-RTLEGFVK
FLEGEKDEQPEEEEKDDKP-----------------------------------------
----------------------TKDEL---------------------------------
--------------------------------
>gi|39645929|gb|AAH63979.1|	Danio rerio
-----------------MKKI-------------TLLLIMLLG--VTHFIKPHRCEDDAK
DDSAEDLGEEEDDDDDDDDDDDEDADDTEVKEENGVLVLTDANFDTFIEGKDTVLVEFYA
PWCGHCKQFAPEYEKIAQTLKENDPPIPVAKVDATKASGLGSRFEVSGYPTIKILKKGEP
LDYDGDRSEHAIVERVKEVAQPDWKPPPEATLVLTKDNFDDVVNN---ADIILVEFY---
--APWCGHCKRLAPEYEKAAKELSNRTPPIPLAKVDATAES-DLATRFGVSGYP-TLKIF
RKGK----------------------------------------------AFDYNGPREK
FGIVDYMSDQAGPPSKQVQ-----TLKQVQELLRDG-DDAVIVGVFSSDEDAAYEIYQEA
CNSLREDYKFMHTFNNDVTKFLKASPGQ-VVMLQPEKFRSKYESASHSLTIK-DS--TPA
SEVQDFFKKHILPLVGHRKQSNDAKRY-TKRPLVVVYYGVDFSFDYRVATQFWRSKVLEV
AKDFP----EYTFAIADEED-------------YADELKSLGL-SESGEEVNVGIVGEGG
KKYAMEP-EEFDSD--VLRSFVMAFKKGKLKPIVKSQPLPKN-NKGPVKVVVGKTFDEIV
MD-----------------------SKKDVLIEFYAPWCGHCKKLEPDYISLGKKYKNEK
N------LVIAKMDATANDVPHDS-YKVEGFPTIYFAPSNNKQNPIKFEGGKRDVEEFSK
FVEKHATKLSH-------------------------------------------------
----------------------KKDEL---------------------------------
--------------------------------
>gi|66804043|gb|AAY56660.1|	Drosophila simulans
-----------------MMW--------------RLAGVLLLG-----------------
---------FIAISSGAEQD----------------------------------------
------------------------------------------------------------
------------------------------VLELGDDDFATTLKQ---HETTLVMFY---
--APWCGHCKRLKPEYAKAAEIVKDDDPPIKLAKVDCTEAGKETCSKYSVSGYP-TLKIF
RQDE---------------------------------------------VSQDYNGPREA
SGIAKYMRAQVGPASKTVR-----TVAELKKFLDT--KDTTLFGYFSDSDSKLAKIFLKF
ADKNREKYRFGHSSEKEVLEKQGETDK--IVLIRAPHLSNKFESSSIKFE---GS---SE
SDLSTFVKENYHGLVGHRTQDSVKDF---QNPLITAYYSVDYQKN-PKGTNYWRNRVLKV
AKEFVGQI---NFAIASKDD-------------IQHELNEYGYDFVGDKPVILARDEKNL
K-YALK--DEFSVE--NLQDFVEKLLANELEPYIKSEPIPES-NDAPVKVAVAKNFDDLV
IN-----------------------NGKDTLIEFYAPWCGHCKKLTPIYEELAEKLQ-DE
D------VAIVKMDATANDVPPE--FNVRGFPTLFWLPKDAKNKPVSYNGG-REVDDFLK
YIAQEATTELKGFDRSGQA-----------------------------------------
----------------------KKTEL---------------------------------
--------------------------------
>gi|2501202|sp|Q12730|PDI_ASPNG	Aspergillus niger
-----------------MRSF-------------APWLVSLLG-----------------
-------ASAVVAAADTESD----------------------------------------
------------------------------------------------------------
------------------------------VISLDQDTFESFMNE---HGLVLAEFF---
--APWCGHCKALAPKYEEAATELKAK--NIPLVKVDCTAEE-DLCRSQGVEGYP-TLKIF
RGVD---------------------------------------------SSKPYQGARQT
ESIVSYMIKQSLPAVSSV------NEENLEEIKTM--DKIVVIGYIPSDDQETYQAFEKY
AESQRDNYLFAATDDAAIAKSEGVEQPS-IVLYK------DFDEKKAVYD---GE--IEQ
EAIHSWVKSASTPLVGEIGPETYSGYIGAGVP--LAYIFAETKEEREKYTEDFK----PI
AQKHKGAI-NIATIDAKM---------------FGAHAGNLNLDSQKFPAFAIQDPAKNA
K-YPYDQAKELNAD--EVEKFIQDVLDGKVEPSIKSEPVPES-QEGPVTVVVAHSYKDLV
ID-----------------------NDKDVLLEFYAPWCGHCKALAPKYDELAALYADHP
DLA-AK-VTIAKIDATANDVPD----PITGFPTLRLYPAGAKDSPIEYSGS-RTVEDLAN
FVKENGKHNVDALNVASEETQEGGDVTEAAP-SATEAETPAATDDE--------------
--------------------KAEHDEL---------------------------------
--------------------------------
>gi|94962706|gb|ABF48564.1|	Conus marmoreus
-----------------MKF---------------SSCLVLTL-----------------
------LVFVSADDIKQEEG----------------------------------------
------------------------------------------------------------
------------------------------VYVLTKKNFDSFITE---NEFVLVEFY---
--APWCGHCKALAPEYAKAATTLEEEKLNIKLGKVDATVEE-DLASKFEVRGYP-TIKFF
HKEKP-------------------------------------------NKPADYNGGRQA
VDIVNWLKKKTGPPAKELK-----EKEEVKSFVEK--DEVVVIGFFKDQESTGALAFKKA
AAGI-DDIPFAITSEDHVFKEYKMDKDG-IVLLK------KFDEGRNDFD---GE--FEE
EAIVKHVRENQLPLVVEFTQESAQKIFGGEVKNHILLFLKKEGGE--DTIEKFR----GA
AEDFKGKV-LFIYLDTDNEE-------------NGRITEFFGLKDDEIPAVRLIQLAEDM
SKYKPES-SDLETA--TIKKFVQDFLDGKLKPHLMSEDVPDDWDAKPVKVLVGKNFKEVA
MD-----------------------KSKAVFVEFYAPWCGHCKQLAPIWDELGEKYKDSK
D------IVVAKMDATANEIEE---VKVQSFPTLKYFPKDSEE-GVDYNGE-RTLDAFVK
FLESDGTEGAGVPEDEEEEEEDEEGDDEDL------------------------------
----------------------PRDEL---------------------------------
--------------------------------
>gi|15384813|emb|CAC59703.1|	Ustilago maydis
-----------------MRP--------------LFYAPALTL-----------------
-------------------T----------------------------------------
------------------------------------------------------------
------------------------------PLFVAAVFYRPSVPA--QQPLMLVEFY---
--APWCGHCKALAPEYEKASTELLAD--KIKLAKVDCTEEN-ELCAEHGVEGFP-TLKVF
RTGS----------------------------------------------SSEYNGNRKA
DGIVSYMKKQALPALSEL------TADSYADFKSK--DRVVAIAYLDSSDKAHLDAVNAV
ANNLRDNYLFGVVHDAAVAEKAGVTAPA-FVVYR------QFDEPEVKFD---GK-SFNE
EAITNFIKAESIPLIDELNAENFMSYAESGLPL-AYLFADPESKDLKSTVESLK----SL
ARANKGKL-NFVWIDGVK---------------YSAHAKSLNIQGEDWPAFAVQDIEQNL
K-FPLEDLSGDLVA--KVTDFVSQYTSGSLKPSVKSEPIPKD-QDGPVHVLVADEFDAVI
GD-----------------------DSKDKLVEFYAPWCGHCKKLAPTYDTLGEKYKAHK
D----K-VLIAKMDATANDIPPSAGFQVQSFPTIKFQAAGSKD-WIEFTGE-RSLEGFVD
FIALNGKHKVSVDLDPINVTEQAAPAKEAP------------------------------
----------------------HHEEL---------------------------------
--------------------------------
>gi|112984454|ref|NP_001037171.	Bombyx mori
-----------------MRVL-------------IFTAIALLG-----------------
--------LALGDEVPTEEN----------------------------------------
------------------------------------------------------------
------------------------------VLVLSKANFETVIST---TEYILVEFY---
--APWCGHCKSLAPEYAKAATKLAEEESPIKLAKVDATQEQ-DLAESYGVRGYP-TLKFF
RNGS----------------------------------------------PIDYSGGRQA
DDIISWLKKKTGPPAVEVT-----SAEQAKELIDA--NTVIVFGFFSDQSSTRAKTFLST
AQVV-DDQVFAIVSDEKVIKELEAEDED-VVLFK------NFEEKRVKYE-D-EE--ITE
DLLNAWVFVQSMPTIVEFSHETASKIFGGKIKYHLLIFLSKKNGDFEKYLEDLK----PV
AKTYRDRI-MTVAIDADEDE-------------HQRILEFFGMKKDEVPSARLIALEQDM
AKYKPSS-NELSPN--AIEEFVQSFFDGTLKQHLLSEDLPADWAAKPVKVLVAANFDEVV
FD-----------------------TTKKVLVEFYAPWCGHCKQLVPIYDKLGEHFENDD
D------VIIAKIDATANELEH---TKITSFSTIKLYSKDNQ--VHDYNGE-RTLAGLTK
FVETDGEGAEPVPSVTEFEEEEDVP-----------------------------------
----------------------AKDEL---------------------------------
--------------------------------
>gi|1709618|sp|P55059|PDI_HUMIN	Humicola insolens
-----------------MHKA-------------QKFALGLLA-----------------
-----------AAAVATASD----------------------------------------
------------------------------------------------------------
------------------------------VVQLKKDTFDDFIKT---NDLVLAEFF---
--APWCGHCKALAPEYEEAATTLKEK--NIKLAKVDCTEET-DLCQQHGVEGYP-TLKVF
RGLD---------------------------------------------NVSPYKGQRKA
AAITSYMIKQSLPAVSEV------TKDNLEEFKKA--DKAVLVAYVDASDKASSEVFTQV
AEKLRDNYPFGSSSDAALAEAEGVKAPA-IVLYK------DFDEGKAVFS---EK--FEV
EAIEKFAKTGATPLIGEIGPETYSDYMSAGIP--LAYIFAETAEERKELSDKLK----PI
AEAQRGVI-NFGTIDAKA---------------FGAHAGNLNLKTDKFPAFAIQEVAKNQ
K-FPFDQEKEITFE--AIKAFVDDFVAGKIEPSIKSEPIPEK-QEGPVTVVVAKNYNEIV
LD-----------------------DTKDVLIEFYAPWCGHCKALAPKYEELGALYAKSE
F-K-DR-VVIAKVDATANDVPD----EIQGFPTIKLYPAGAKGQPVTYSGS-RTVEDLIK
FIAENGKYKAAISEDAEETSSATETTTETATKSEEAAKETAT------------------
----------------------EHDEL---------------------------------
--------------------------------
>gi|149607111|ref|XP_001517226.	Ornithorhynchus anatinus
-----------------MPTG-------------GLLCLALAL-----------------
----ALAGGVRADAPEEEDH----------------------------------------
------------------------------------------------------------
------------------------------VLVLKKSNFEEALAA---HKFLLVEFY---
--APWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEES-DLAQQYGVRGYP-TIKFF
KNGDT-------------------------------------------ASPKEYTAGREA
DDIVNWLKKRTGPAAATLP-----DVAAAEALVES--SDVAVVGFFKDAGSEPAKQFLAA
AESI-DDIPFGITSGGEVFAKYQLDEDG-VVLFK------KFDEGRNSFS---GE--VTK
ENLSNFIKQNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVADYDGKLNNFK----KA
AGSFKGKI-LFIFIDSDHTD-------------NQRILEFFGLKKEECPAVRLITLEEEM
TKYKPES-DELTAD--KIKEFCDRFLEGKVKPHLMSQDLPADWDKQPVKVLVGKNFEEVA
FD-----------------------EKKNVFVEFYAPWCGHCKQLAPIWDKLGEAFKDHE
N------VVIAKMDSTANEVEA---VKVHSFPTLKFFPASAEKTVIDYNGE-RTLEGFTK
FLESGGQDGAADDDDLEDLEEAEEPDLEEDDDQKN-------------------------
----------------------LRDEL---------------------------------
--------------------------------
>gi|58332266|ref|NP_001011281.1	Xenopus tropicalis
-----------------MRWL-----------TALQLCLLCTF-YTV----ALGQNATSE
EPTKNSSEEETSDELLEEDN----------------------------------------
------------------------------------------------------------
------------------------------VLVLNKKNFDKALET---YKYLLVEFY---
--APWCGHCQELAPKYAKAAEILKDKSEEVRLAKVDATVES-ELSMEFNVNGYP-TLKFF
KGGNR-------------------------------------------TGHIDYGGKRDQ
DGLVKWMLRRLGPAAIVLD-----KVESAEKFTSS--QESPVIGFFKNPEDADIKIFYEA
AELN-EDFTFALAHDAKLFEKFGVTEDT-VIFFKNSEEKPEFKVDEDLG--------LDK
DELSKFLKINNIDLVTEYSAETSDKIFAAQIPNHLLLFINKTEDSQLALLEHFR----KA
ATHFKGKI-LFVFIDSDGG--------------FSSVLEYFGLKSSDVPTLRFINL-ESV
KKYAFDA-PEITED--TIQTFCRTVLEGNVKQNLMSEEIPADWDKNPVKVLVGKNFEEVA
YD-----------------------ESKSVFVEFYAPWCSHCKELEPVWEELGEKYKDHE
S------VIIAKMDATANEIDG---LRVRGFPNLRFFPAGPGRKMIEYTKE-RTVELFSA
FIDSGGVLPEEQVEKDAEAEESKEVAEEDK------------------------------
----------------------GKDEL---------------------------------
--------------------------------
>gi|90075102|dbj|BAE87231.1|	Macaca fascicularis
-----------------MLRR-------------ALLCLAVAA-----------------
------AARVYADAPEEEDH----------------------------------------
------------------------------------------------------------
------------------------------VLVLRKSNFAEALAA---HKYLLVEFY---
--APWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEES-DLAQQYGVRGYP-TIKFF
RNGDT-------------------------------------------ASPKEYTAGREA
DDIVNWLKKRTGPAATTLP-----DGAAAESLVES--SEVAVIGFFKDVESDSAKQFLQA
AEAI-DDIPFGITSNSDVFSKYQLDKDG-VVLFK------KFDEGRNNFE---GE--VTK
ENLLDFIKYNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYGGKLSSFR----TA
AESFKGKI-LFIFIDSDHTD-------------NQRILEFFGLKKEECPAVRLITLEEEM
TKYKPES-DELTAE--RITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEEVA
FD-----------------------ENKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE
N------IVIAKMDSTANEVEA---IKVHSFPTLKFFPASVDRTVIDYNGE-RTLDGFKK
FLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKA-------------------------
----------------------VKDEL---------------------------------
--------------------------------
>gi|126335373|ref|XP_001372460.	Monodelphis domestica
-----------------MPN----------------PSLLLGG-LLSGDLAQFPYPNRDS
KAPDHSSSGSAAISLEEEDD----------------------------------------
------------------------------------------------------------
------------------------------ILVLTQHNFGRALQE---HRYLLVEFY---
--APWCGHCRALAPEYAKAASLLKNESSELKLAKVDGPAEK-ELAEEFGVTGYP-ALKFF
KDGNR-------------------------------------------SQPVEFTGPREA
EGIVRWLKRRLGPSATRLE-----TEAEAAQFIDS--QDIVIVGFFKDLQDEDVAGFLAI
AEDA-VDLTFGLTDRPELFQKYDLSRDT-VVLFK------KFDEGRADFPVD-EELGLDQ
ADLTHFLVVHSMHLVTEFNSQTSSKIFEARILNHLLLFINQTLSPHRELLKGFQ----EA
APAFRGEI-LFVVVDVAGE--------------NDHVLQYFGMNATDAPTLRLINVETTK
K-YVPGAGGEITAA--SVSAFCQDVLSGKVKPHLRSQEIPADWDQKPVKVLVGKNFEEVA
FD-----------------------ASKNVFVKFYAPWCTHCKEMAQTWEDLAEKYKDRE
D------IVIAELDSTANELEA---FAIRGFPTLKYFPAGPDRKVIEYKSS-RDLETFSK
FLDNGGVLPEPEPKEPEVPLPEAGANDSKD------------------------------
----------------------HKDEL---------------------------------
--------------------------------
>gi|149723431|ref|XP_001489541.	Equus caballus
-------------MQHEGFRR-------------RRRGSAPGWDSAPLPRRRRIARRRSH
LMANQKLRSTGFRRWQHSKT----------------------------------------
------------------------------------------------------------
----------------------PRKWTWKPSVTILKEKGREVVRL---GRVLLSESCFLF
SDAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEES-DLAQQYGVRGYP-TIKFF
KNGDT-------------------------------------------ASPKEYTAGREA
EDIVNWLKKRTGPAATTLP-----DGAAAEALVES--SEVTVIGFFKDVESDFAKQFLLA
AEAI-DDIPFGITSSSDVFSKYQLDKDG-VVLFK------KFDEGRNNFE---GE--ITK
EKLLDFVKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFK----KA
AESFKGKI-LFIFIDSDHTD-------------NQRILEFFGLKKEECPAVRLITLEEEM
TKYKPES-DELTAE--KITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEEVA
FD-----------------------EKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE
N------IVIAKMDSTANEVEA---VKVHSFPTLKFFPASADRTVIDYNGE-RTLDGFKK
FLESGGQDGAGDDDDLEDLEEAEEPDLEEDDDQKA-------------------------
----------------------VKDEL---------------------------------
--------------------------------
>gi|148717315|dbj|BAF63671.1|	Haemaphysalis longicornis
-------------MISLKVV--------------SLLCCIAAI-----------------
----------SCDDYEIDDH----------------------------------------
------------------------------------------------------------
------------------------------VLVLKTDNFEKGIKE---HKNVFVKFY---
--SPWCGHCKAMAPDYHKVAKLLEEEKSDIKLAKVDATVES-QLAEQHNIQGYP-TLKFY
RDGE----------------------------------------------PIEYKGGRTV
DEMVRWLKKKTGPSAQTLA-----SVEEAKEFVES--ADVTVVGFFKDIASKEAKEFMSA
ADAV-DRHPFAITSDDAIYKELGANKDG-VMLFK------KFDEGKNTMD---TE--ITS
ENVQKFVQLNSLPLVVEFTHESAATVFSGQIRQHNLLFISKKNSDFRQLVDDFR----KA
AEAFRHKV-LFVTIDVDDED-------------HERILEFFGLKKEQVPAMRIIQLEGDM
TRFKPET-DSLAVE--DIKKFVQGVLDGTIKQSLLSQDLPEDWDKHPVKVVVSSNFDEVV
MD-----------------------KSKDVLVEFYAPWCGHCKQLAPIYDELAEKYKDRD
D------ILIVKMDSTANELEH---TKIGSFPTIKLYKKETNE-AVDYNGE-RTLEGLSK
FLDTNGEYGQAPPEDVEEEEEEEEDKDDK-------------------------------
----------------------KRDEL---------------------------------
--------------------------------
>gi|114326226|ref|NP_001039344.	Bos taurus
-----------------MRPR-------------KAWMLVLLL-ALVQLLAVASAGAPDE
DSTDKEDAIEEDEEEDEDDD--DDDDDLEVKEENGVLILNDANFDNFVADKDTVLLEFYA
PWCGHCKQFAPEYEKIAATLKENDPPIPVAKIDATSESALASRFDVSGYPTIKILKKGQE
VDYEGSRTQEEIVAKVKEVSQPNWTPPPEVTLVLTKDNFDEVVND---ADIILVEFY---
--APWCGHCKKLAPEYEKAAKELSKSSPPIPLAKVDAIAET-DLAKRFDVSSYP-TLKIF
RKGK----------------------------------------------AFSYNGPREK
YGIVDYMMEQSGPPSKQIL-----ALKQVQEFLKDG-DDVIIIGVFKSESDPAYQLYQDA
ANSLREDYKFHHTFSTEIAKFLKVSLGK-LVVMQPEKFQSKYEPKSYVMDIK-DS--TEA
AAITEHVVKHTLPLVGHRKAADAKRY--TRRPLVVVYYSVDFSFDYRAATQFWRNKVLEV
AKDFP----EYTFAVADEED-------------FATELKDLGL-SESGEEVNAAILDEGG
RRFAMEP-DDFDAD--ALRDFVTAFKKGKLKPVIKSQPVPKN-NKGPVKVVVGKTFDSIV
MD-----------------------PKKDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGHK
N------LVIAKMDATANDVTSDR-YKVEGFPTIYFAPSGDKKKPIKFEDGNRDLEHLSK
FIEEHATKLSR-------------------------------------------------
----------------------TKEEL---------------------------------
--------------------------------
>gi|17647799|ref|NP_524079.1|	Drosophila melanogaster
-----------------MKF---------------LICALFLA-ASY-------------
------VAASAEAEVKVEEG----------------------------------------
------------------------------------------------------------
------------------------------VLVATVDNFKQLIAD---NEFVLVEFY---
--APWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEG-ELAEQYAVRGYP-TLKFF
RSGS----------------------------------------------PVEYSGGRQA
ADIIAWVTKKTGPPAKDLT-----SVADAEQFLKD--NEIAIIGFFKDLESEEAKTFTKV
ANAL-DSFVFGVSSNADVIAKYEAKDNG-VVLFK------PFDDKKSVFE---GE--LNE
ENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLK----EI
AKKYRDDI-LFVTISSDEED-------------HTRIFEFFGMNKEEVPTIRLIKLEEDM
AKYKPES-DDLSAE--TIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVA
LD-----------------------KSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNE
D------IVIAKMDSTANELES---IKISSFPTIKYFRKEDNK-VIDFNLD-RTLDDFVK
FLDANGEVADSEPVEETEEEEEAP------------------------------------
----------------------KKDEL---------------------------------
--------------------------------
>gi|109080868|ref|XP_001109061.	Macaca mulatta
-----------------MRL--------------RRLALFPGV-----------------
------ALLLAAARLAAASD----------------------------------------
------------------------------------------------------------
------------------------------VLELTDDNFESRVSDTGSAGLMLVEFF---
--APWCGHCKRLAPEYEAAATRLKGI---VPLAKVDCTANT-NTCNKYGVSGYP-TLKIF
RDGE---------------------------------------------EAGAYDGPRTA
DGIVSHLKKQAGPASVPLR-----TEEEFKKFISD--KDASVVGFFDDLFSEAHSEFLKA
ASNLRDNYRFAHTNVKSLVNEYDDNGEG-IILFRPSHLTNKFEDKTVAYT---EQ-KMTS
GKIKKFIQENIFGICPHMTEDNKDLIQGKDL--LIAYYDVDYEKN-AKGSNYWRNRVMMV
AKKFLDAGHKLNFAVASRKT-------------FSHELSDFGLESTAGEIPVVAIRTAKG
EKFVMQ--EEFSRDGKALERFLQDYFDGNLKRYLKSEPIPES-NDGPVKVVVAENFDEIV
NN-----------------------ENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDP
N------IVIAKMDATANDVPSP--YEVRGFPTIYFSPANKKLNPKKYEGG-RELSDFIS
YLQREATNPPVIQEEKPKKKKK--------------------------------------
----------------------AQEDL---------------------------------
--------------------------------
>gi|91079064|ref|XP_975184.1|	Tribolium castaneum
-----------------MNLL-------------SAFCLIATA-ASL-------------
--------GWASEEIKSDEG----------------------------------------
------------------------------------------------------------
------------------------------VLVLTKSNFKQAITD---NEFILVEFY---
--APWCGHCKALAPEYVKAAKALADQDSKIKLGKVDATEET-ELAEEHQVRGYP-TLKFF
RNGS----------------------------------------------PIDYNGGRQA
DDIVAWLLKKTGPPAKEIK-----TVEEAKEFIDA--SNVAVIGFFKDQTTDKAKAFLAA
AATI-DDYPFGITSEDSVYKEYEAECGS-IVLFK------KFDEGKVLFE---GE--ATE
KNIKKFVAGNSLPLIVEFNHETAQKIFGGDIKSHLLLFLNKGEDHFEKVSEAAR----AV
AKPFKEQV-LFVTIDAGEED-------------HQRILEFFGMKKEEVPAARLIKLEEDM
AKYKPET-DELSSE--SIKKFVEDFLAGKLKQHLLSQDLPEDWDKEAVKVLVATNFDSVV
FD-----------------------ADKDVLVEFYAPWCGHCKQLAPIYDKVGEHFKDDK
S------VVVAKIDATANELEH---TKITSFPTLKFYPKGGNN-VIEYNGP-RTFEGLVK
FIESGGVDGAGVDEPVEEETEDDDSP----------------------------------
----------------------RKDEL---------------------------------
--------------------------------
>gi|4758304|ref|NP_004902.1|	Homo sapiens
-----------------MRPR-------------KAFLLLLLL--GLVQLLAVAGAEGPD
EDSSNRENAIEDEEEEEEEDDDEEEDDLEVKEENGVLVLNDANFDNFVADKDTVLLEFYA
PWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQA
VDYEGSRTQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVND---ADIILVEFY---
--APWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAET-DLAKRFDVSGYP-TLKIF
RKGR----------------------------------------------PYDYNGPREK
YGIVDYMIEQSGPPSKEIL-----TLKQVQEFLKDG-DDVIIIGVFKGESDPAYQQYQDA
ANNLREDYKFHHTFSTEIAKFLKVSQGQ-LVVMQPEKFQSKYEPRSHMMDVQ-GS--TQD
SAIKDFVLKYALPLVGHRKVSNDAKRY-TRRPLVVVYYSVDFSFDYRAATQFWRSKVLEV
AKDFP----EYTFAIADEED-------------YAGEVKDLGL-SESGEDVNAAILDESG
KKFAMEP-EEFDSD--TLREFVTAFKKGKLKPVIKSQPVPKN-NKGPVKVVVGKTFDSIV
MD-----------------------PKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQK
G------LVIAKMDATANDVPSDR-YKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSK
FIEEHATKLSR-------------------------------------------------
----------------------TKEEL---------------------------------
--------------------------------
>gi|3392892|emb|CAA12644.1|	Fasciola hepatica
-----------------MMSVRQ-----------VLWLLLCVC-----------------
------TRYTACEESVDESA----------------------------------------
------------------------------------------------------------
------------------------------VVELTEETFDDEIKK---KEFAMVMFY---
--APWCGHCKAMKPEYARAAAQLKEEGSDIMIAKVDATQHS-KLAKSHNVTGYP-TLKFY
KSGV----------------------------------------------WLDYTGGRQT
KEIVHWIKRKVSPAVSVLS-----TLSEVQQLVDK--EDIVVIAFAEESNEELKQLLEAV
ASVY-DKYEFGFVSSKDAFDHYKIDSKSRVVLFK------KFDEGRADFD---GE--LTR
EALIEFMQKETIPLVVEFTQETASAVFGSAIRKHVVSFVPK-SKDYDKFVATLK----ES
AKKFKGKA-HFIIIDTDVAD-------------NQRILEFFGMTSADVPGYRMINLAEDM
TKYKPDS-SDFTEE--AISAFVEEVLSGKRKPFLMSQEIPSP-SSDPVRVLVGKNYNEVV
SD-----------------------LSKAVFVELYAPWCGHCKQLAPIWDELGEAYKTKE
D------LIIAKMDATANEAEG---LSVQSFPTLKYYPKGSSE-PIEYTGE-RTLEALKR
FVDSEGKGAQKEETEAE-------------------------------------------
----------------------PHEEL---------------------------------
--------------------------------
>gi|121715212|ref|XP_001275215.	Aspergillus clavatus
-----------------MRSF-------------APWIVSLLG-ASV-------------
------VVSATDTSADAPSD----------------------------------------
------------------------------------------------------------
------------------------------VVTLTKDSFDDFMKA---HDLVLAEFY---
--APWCGHCKALAPKYEEAATELKGK--NIPLVKVDCTAEE-ELCRDNGVEGYP-TLKIF
RGPE---------------------------------------------SSKPYQGARQA
DSIVSYMVKQSLPAVSPV------TEDNLEDVKTM--DKIVVIGYLPSDDKAANDAFTSF
AESQRDNYLFAATSDSAIAKAEGVKQPS-IVLYK------DFDEKKAVYD---GK--LDQ
EAILSWVKTASTPLVGEIGPETYSGYMAAGIP--LAYIFAETQEEREKFTEDFK----PI
AEKHKGAI-NIATIDAKM---------------FGAHAGNLNLDPQQFPAFAIQDPEKNT
K-YPYDQTKEINAK--DIAKFIQDVLDGKVEPSIKSEPIPET-QEGPVTVVVAHSYQDLV
ID-----------------------NDKDVLLEFYAPWCGHCKALAPKYDELAALYSGDL
A---SK-VTIAKIDATANDVPD----SITGFPTIKLYPAGAKDSPVEYSGS-RTVEDLAD
FVKENGKHKVDGLEASSQETEEGADVTASASASSTETEAPAATEDE--------------
--------------------KADHDEL---------------------------------
--------------------------------
>gi|78099786|sp|P38659|PDIA4_RA	Rattus norvegicus
-----------------MKLR-------------KAWLLVLLL-ALTQLLAAASAEDAHE
DASDSENPIEDDDDEEEDEE---DEDDLEVKEENGVWVLNDENFDNFVADKDTVLLEFYA
PWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLASKFDVSGYPTIKILKKGQA
VDYDGSRTQEEIVAKVREVSQPDWTPPPEVTLTLTKENFDDVVNN---ADIILVEFY---
--APWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQT-DLAKRFDVSGYP-TLKIF
RKGR----------------------------------------------PFDYNGPREK
YGIVDYMVEQSGPPSKEIL-----TLKQVQEFLKDG-DDVVILGVFQGVGDPGYLQYQDA
ANTLREDYKFHHTFSTEIAKFLKVSLGK-LVLMQPEKFQSKYEPRMHVMDVQ-GS--TEA
SAIKDYVVKHALPLVGHRKTSNDAKRY-SKRPLVVVYYSVDFSFDYRTATQFWRNKVLEV
AKDFP----EYTFAIADEED-------------YATEVKDLGL-SESGEDVNAAILDESG
KKFAMEP-EEFDSD--ALQEFVMAFKKGKLKPVIKSQPVPKN-NKGPVRVVVGKTFDAIV
MD-----------------------PKKDVLIEFYAPWCGHCKQLEPVYTSLGKKYKGQK
D------LVIAKMDATANDITNDR-YKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSK
FIDEHATKRSR-------------------------------------------------
----------------------TKEEL---------------------------------
--------------------------------
>gi|73978407|ref|XP_848238.1|	Canis familiaris
-----------------MRPR-------------TAWLLLLLL-LALAHLLAAAGPDGDS
SNKEDAIEDEEEEDDDEEEE----EDDLEVKEENGVLVLNDINFDNFVADKDTVLLEFYA
PWCGHCKQFAPEYEKIASTLKENDPPIPVAKIDATSESALAGRFGVSGYPTIKILKKGEA
VDYEGSRTQEEIVAKVKEVSQPNWTPPPEVTLVLTKENFDDVVNG---ADIILVEFY---
--APWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAET-DLAKRFEVSSYP-TLKIF
RKGK----------------------------------------------PFDYNGPREK
YGIVDYMIEQSGPPSKEIM-----ALKQVQEFLKDG-DDVIIIGVFKAESDPAYQQYQDA
ANNLREDYKFHHTFSTEIAKFLKVSSGK-LVVMQPEKFQSKYEPRSNVLDIQ-DA--RAA
SRVVAWIQFHVLPAQGHLPMSHPDGPQPRVKSMVFTSHLLLCSLGGQLTTQFWRNKVLEV
AKDFP----EYTFAVADEDD-------------FASEVRDLGL-SESGEDVNAAILAEGG
RRFAMEP-DDFDAD--ALREFVRAFQDGTLKPVVKSQPVPKN-NKGPVKVVVGKTFDSVV
MD-----------------------PKKDVLIEFYAPWCGHCKQLEPEYAALGKKYKNRK
N------LVIAKMDATANDITSDR-YRVDGFPTIYFAPRGDKKNPIKFEDGNRDLEHLSK
FVEEHATKLSR-------------------------------------------------
----------------------TREEL---------------------------------
--------------------------------
>gi|47223486|emb|CAF97973.1|	Tetraodon nigroviridis
-----------------MKKL-------------ALLLVVLLG-VAHFITVSKCQDDDTE
KEETGEDSDDDSEDEDEEED------DTEVKEENGVLVLTDANYDTFMEGKDTILVEFYA
PWCGHCKQFAPEYEKIAQTLKENDPPIPVAKVDATSSSGLGSRFDVSGYPTIKIIKKGEP
VDYDGARTEAAIVERVREVSQPDWKPPPEATLVLTKDNFDDTVNE---ADIILVEFY---
--APWCGHCKRLAPEYEKAAKELSQRSPPIPLAKVDATVEN-ELASRFQVSGYP-TLKIF
RKGK----------------------------------------------VFDYNGPREK
YGIVEHMTEQAGPPSRQVQ-----AAKQVQELIKDG-DDAVIVGVFSSQQDAAFEIYTEA
CNALREDFTFRHTFSSEVSNLLKASPGQ-AVIVQPEKFRSKYEPGSHKLTIK-DN--MLV
AEVQEFFKKHVVPLVGHRKPNNDAKRY-TKRPLVVVYYGVDFSFDYRKATQFWRSKVLEV
AKDFP----EYTFAIADEED-------------YGEELKSLGL-SESGEEVNVAILADGG
KKYAMEP-EELDAD--VLRDFVVAFKKGKLKPIIKSQPVPKN-NKGAVKVVVGKTFDDIV
MD-----------------------TSKDVLIELYAPWCGHCKKLEPDYLALAKKYKGEN
H------LVIAKMDATANDVPNDS-FKVEGFPTIYLAPSNRKQEPIKFEGGDRTVEGLTR
FLEKHATKLS--------------------------------------------------
----------------------QKDEL---------------------------------
--------------------------------
>gi|2501203|sp|Q00248|PDI_ASPOR	Aspergillus oryzae
-----------------MRTF-------------APWILSLLG-ASA-------------
------VASAADATAEAPSD----------------------------------------
------------------------------------------------------------
------------------------------VVSLTGDTFETFVKE---HDLVLAEFF---
--APWCGHCKALAPKYEQAATELKEK--NIPLVKVDCTEEE-ALCRDQGVEGYP-TLKIF
RGLD---------------------------------------------AVKPYQGARQT
EAIVSYMVKQSLPAVSPV------TPENLEEIKTM--DKIVVIGYIASDDQTANDIFTTF
AESQRDNYLFAATSDASIAKAEGVKQPS-IVLYK------DFDEKKATYD---GE--IEQ
DALLSWVKTASTPLVGELGPETYSGYITAGIP--LAYIFAETKEEREQFTEEFK----FI
AEKHKGSI-NIVTIDAKL---------------YGAHAGNLNLDPSKFPAFAIQDPEKNA
K-YPYDQSKEVKAK--DIGKFIQDVLDDKVEPSIKSEAIPET-QEGPVTVVVAHSYKDLV
LD-----------------------NEKDVLLEFYAPWCGHCKALAPKYEELASLYKDIP
E------VTIAKIDATANDVPD----SITGFPTIKLFAAGAKDSPVEYEGS-RTVEDLAN
FVKENGKHKVDALEVDPKKEQESGDATETRA-ASDETETPAATSDD--------------
--------------------KSEHDEL---------------------------------
--------------------------------
>gi|47551041|ref|NP_999697.1|	Strongylocentrotus purpuratus
-----------------MKY--------------LALCFIALA-----------------
------CAVHAAVEVEIEED----------------------------------------
------------------------------------------------------------
------------------------------VAVLTDAAFADYVAE---NEFVLVEFY---
--APWCGHCKSLAPQYSIAAKTLKDSGSSIKLAKVDATVET-QLPGKYGVRGYP-TLKFF
RSGK----------------------------------------------DSEYAGGRTG
PEIVAWLNKKTGPPAATIA-----SVEDAEAFLAD--KEVAVIGFFKDVP----QTFLDV
AVNI-DDIPFAIVSDDAVISNYEAKDGS-IILFK------KFDEGKNVFE---GE--LTS
EDLTSFVRKNSLSVVTEFGEETASKIFGGEIKIHNLLFVKKDSDDFKTIYDQFY----AA
ATTFKGEV-LFVLIDAAAES-------------NSRILEYFGLGDEEVPTVRLITLDGDM
KKYKPTV-PELTTE--SLSQFVIDFKDGKLKPHLMSESVPEDWNANPVTILVGENFAEVA
LD-----------------------PTKDVLVEFYAPWCGHCKQLAPIYEELGEHFKERE
D------VVIAKVDSTKNEVED---AVVRSFPTLKFWKKGENE-MVDYSGD-RTLEAMIQ
FVESGGEIIAEVDDEDMEEDEEMDEGAEDQ------------------------------
----------------------AKDEL---------------------------------
--------------------------------
>gi|68533908|gb|AAH99308.1|	Xenopus laevis
-----------------MRWL-----------IFLQFCLLSTF-YSS----AFGQNDATE
EPTKSSSEEETSDELLEEDN----------------------------------------
------------------------------------------------------------
------------------------------VLVLNKRNFNKALET---YKYLLVEFY---
--APWCGHCQELAPKYTKAAEILKDKSEEVRLAKVDGTVET-DLSTEFNVNGYP-TLKFF
KGGNR-------------------------------------------TGHIDYGGKRDQ
DGLVKWMLRRMGPAAVVLD-----NVESAEKFTSS--QEFPVIGFFKYPEDADIKIFYEV
AELQ-EDFTFALAHDEKLFEKFGVTEDT-VIFFKKSEENLNFKPDEDL-----G---LDK
DELSKFLRINSIDLVTEYSAETSDKIFAAQIPNHLLLFINKSDDSQLVLLEHFR----KA
APDFKGKV-LFVFIDSNGG--------------YASVLEYFGLKSSDVPTLRFINL-ESV
KKYVFNA-PEITED--TIQAFCRSVLEGNVKQNLMSEEIPEDWDKSPVKVLVGKNFEEVA
YD-----------------------ETKNVFVEFYAPWCSHCKEMEPVWEELGEKYKDHE
N------VIIAKIDATANEIDG---LRVRGFPNLRFFPAGPERKMIEYTKE-RTVELFSA
FIDSGGVLPDEQETKEAEAEESKEAAEEDK------------------------------
----------------------GKDEL---------------------------------
--------------------------------
>gi|115398391|ref|XP_001214787.	Aspergillus terreus
-----------------MRSF-------------APLALSLLG-ASA-------------
------VVSAADATAETESD----------------------------------------
------------------------------------------------------------
------------------------------VVSLTKDTFKPFMEE---NNLVLAEFF---
--APWCGHCKALAPKYEEAATELKGK--NIPLVKVDCTAEE-DLCREQGVEGYP-TMKIF
RGPD---------------------------------------------SSKPYQGARQA
DAIVSYMVKQSLPAVSPV------TEENLEEVKTM--DKIVVIGYFAEDDKATKDAFTTF
AEAQRDNYLFAAASDEAIAKAEGVKQPA-VVLYK------DFDEKKAVYK---GD--IEQ
DALLSWVKTASTPLVGEIGPETYSGYMSAGIP--LAYIFAQTKEEREKFAEEFK----PI
AEKHKGAI-NIATIDAAM---------------FGAHAGNLNLDTEKFPAFAIQDPSKNA
K-YPYDQDKELKAK--DVGKFIKDVLDGKVEPSIKSEPIPET-QEGPVTVVVAHSYKELV
ID-----------------------NEKDVLLEFYAPWCGHCKALAPKYDELAELYAKNE
DFA-SK-VTVAKIDATANDVPD----SITGFPTIKLYPAGSKDSPVEYAGS-RTVEDLAN
FIKENGKHKIDAYAAPAKEAEESSEAAETPS-ESAESEAPAATGEE--------------
--------------------KADHDEL---------------------------------
--------------------------------
>gi|62287156|sp|Q8R4U2|PDIA1_CR	Cricetulus griseus
-----------------MLSR-------------SLLCLALAW-----------------
------VARVGADAPEEEDN----------------------------------------
------------------------------------------------------------
------------------------------VLVLKKSNFAEALAA---HNYLLVEFY---
--APWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEES-DLAQQYGVRGYP-TIKFF
KNGDT-------------------------------------------ASPKEYTAGREA
DDIVNWLKKRTGPAATTLS-----DTAAAETLIDS--SEVAVIGFFKDVESDSAKQFLLA
AEAV-DDIPFGITSNSGVFSKYQLDKDG-VVLFK------KFDEGRNNFE---GE--VTK
EKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLGNFK----KA
AEGFKGKI-LFIFIDSDHTD-------------NQRILEFFGLKKEECPAVRLITLEEEM
TKYKPES-DELTAE--KITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEEVA
FD-----------------------EKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE
N------IIIAKMDSTANEVEA---VKVHSFPTLKFFPATADRTVIDYNGE-RTLDGFKK
FLESGGQDGAGDDDDV-DLEEALEPDMEEDDDQKA-------------------------
----------------------VKDEL---------------------------------
--------------------------------
>gi|45219865|gb|AAH66857.1|	Mus musculus
-------------GNFDNFV---ADKDTVLLEFYAPWCGHCKQ-FAP-------------
------EYEKIASTLKDNDP----------------------------------------
-------------------------PIAVAKIDATSASMLASKFDVSGYPTIKILKKGQA
VDYDGSRTQEEIVAKVREVSQPDWTPPPEVTLSLTKDNFDDVVNN---ADIILVEFY---
--APWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQT-DLAKRFDVSGYP-TLKIF
RKGR----------------------------------------------PFDYNGPREK
YGIVDYMIEQSGPPSKEIL-----TLKQVQEFLKDG-DDVVIIGLFQGDGDPAYLQYQDA
ANNLREDYKFHHTFSPEIAKFLKVSLGK-LVLTHPEKFQSKYEPRFHVMDVQ-GS--TEA
SAIKDYVVKHALPLVGHRKTSNDAKRY-SKRPLVVVYYSVDFSFDYRAATQFWRNKVLEV
AKDFP----EYTFAIADEED-------------YATEVKDLGL-SESGEDVNAAILDESG
KKFAMEP-EEFDSD--TLREFVTAFKKGKLKPVIKSQPVPKN-NKGPVKVVVGKTFDAIV
MD-----------------------PKKDVLIEFYAPWCGHCKQLEPIYTSLGKKYKGQK
D------LVIAKMDATANDITNDQ-YKVEGFPTIYFAPSGDKKNPIKFEGGNRDLEHLSK
FIDEHATKRSR-------------------------------------------------
----------------------TKEEL---------------------------------
--------------------------------
>gi|116180648|ref|XP_001220173.	Chaetomium globosum
-----------------MHKA-------------HKFALGLLA-----------------
-----------AAAVATASD----------------------------------------
------------------------------------------------------------
------------------------------VVQLKKDTFDEFVKA---NDLVLAEFF---
--APWCGHCKALAPEYEEAATSLKEK--DIKVVKVDCTEEA-DLCQQHGVEGYP-TLKVF
RGLD---------------------------------------------NVSPYKGQRKA
AAITSYMVKQSLPAVSEV------TKDTLEEFKKA--DKVVLVAYLDAADKASSEVFTAA
AEKLRDNYPFGLSTDAALAEAEGVTAPA-VVLYK------DFDEGKSVFS---EK--FDA
EEIEKFAKTAATPLIGEVGPETYSDYMSAGLP--LAYIFAETAEERKEISELLK----PI
AEAQRGVV-NFGTIDAKS---------------FGAHAGNLNLKTDKFPAFAIQEVAKNQ
K-FPFDQEKEITFD--AIKAFVDDFVAGKVEPSIKSEPIPET-QEGPVTVVVAKNYNDIV
LD-----------------------DTKDVLIEFYAPWCGHCKSLAPKYEELAALYGKSE
F-K-DQ-VVIAKVDATANDVPD----EIQGFPTIKLYPAGNKAEAVTYSGS-RTVEDLIK
FIAENGKYKASVSEEVEEPSSAETEAASETETKAEEAKET--------------------
----------------------EHDEL---------------------------------
--------------------------------
>gi|114670980|ref|XP_001164327.	Pan troglodytes
-----------------MVRR-------------ALLCLAVAA-----------------
--------LVRADAPEEEDH----------------------------------------
------------------------------------------------------------
------------------------------VLVLRKSNFAEALAA---HKYLLVEFY---
--APWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEES-DLAQQYGVRGYP-TIKFF
RNGDT-------------------------------------------ASPKEYTAGREA
DDIVNWLKKRTGPAATTLP-----DGAAAESLVES--SEVAVIGFFKDVESDSAKQFLQA
AEAI-DDIPFGITSNSDVFSKYQLDKDG-VVLFK------KFDEGRNNFE---GE--VTK
ENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDSKLSNFK----TA
AESFKGKI-LFIFIDSDHTD-------------NQRILEFFGLKKEECPAVRLITLEEEM
TKYKPES-EELTAE--RITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVA
FD-----------------------EKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHE
N------IVIAKMDSTANEVEA---VKVHSFPTLKFFPASADRTVIDYNGE-RTLDGFKK
FLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKALVPCVGGTEPDWTWSLSTACSVAMT
DHGSCIFWVNGDFQILSGCPPCLEEELVAASPGAQHRPGPSPSLKPGLLLLSWAHCDHWP
LYSMACGLFEAEPGPLTPGWGGGQGCRSCIRR
