>gi|118083050|ref|XP_001235143.	Gallus gallus
--------MYGSARSVGKAE-PSNQ-SPGRSPRLP---------------RSPRL---GH
RRTNSTGGSSG-------SSTGGGSGKTLSMENIQS------------------------
---------LNAAYATSGPMYLSDHENVG-------ADTPK----STMTLGRSGGRLPYG
VR------------MTAMG--------SSPNIASSGVA----------------------
SD-----TIAFGEHHLPPV-------SMASTVPHSLRQARDNT-----------------
----------------IMDLQT----------QLKE-VLRE-------------------
-----NDLLRKDVE----VKES-----KLSS----SMNSIKTF------WSPELKKERAL
RKDEASK-----------------I-T--IWKEQYRV-LQEENQH----MQMTIQALQDE
L---------R---------------------------IQRDLNQLFQQ-----------
-----DSSSRTSEP-----------------------FV-------AELTEENFQRL---
-------------------HTEHERQA------KELFLLRKT--LEEMELR---------
-------IETQKQT-------------LNARDESIKKLL-EMLQSKGLSAKATE-----E
DHE--------------------RTRR------------------LAEAEMHVHHLESLL
EQKEKENNM-------------------------LREEIHRRFEN-----APD-------
---------------SA-----------------KTKALQTVIEMKDS--KISS------
----MERGLRD--LEEEIQMLKSNGA--LSTEER----EEEMKQMEVYRSHSKFMKNKI-
--GQVKQELSRK--DTELLALQTKLETLTN-----------QFSDSKQHIEV--------
LKESLTAKEQRA---------------------------AILQTEVD-ALRLRL---EEK
--------------ETM---LNKK-----------------TKQIQEIAEEKGTQ-----
-----AGEIHDLKDML---EVKERKVNVL-----QKKIENLQE-QLRD------------
--------------------KEKQMSSLKDRVKSLQADTTNTDTALTTL-EEALAEKERT
-----------------------------------IERLKEQRD-----RDEREKQEEID
TYKKDIK-----DLKEKVGI---------LQGDLTEKESSLLDLKEHASSLAS---SGLK
K---DSRLKTLEIALE--------------------------------------------
-------QKKEECLKMETQLKKAHEATLEARA-----SPELSDRM--------QQLEREV
TRYR----------EESSKAQAEVDRLLEILKEME---NEKNDKDKKIA-ELER-----Q
VKDQNKKV----------------------A-----------------------------
------NLKH------------------------KEQVEK---KKSAQMLEE------AR
RREDNLND----SS---QQLQDNLRKKDDRIEE---------------------LEEALR
ESVQITAEREMVLAQEES--ARINAEK---------------------------QVEELM
MA--------ME-KVKQELESMKAK----------------LSSTQQS-------LAEKE
THLTNLRAERRKHLE---------EVLEMKQEALLAAISEKDANIAL-----LELSSS--
-K-------KKTQDEVAALKREKDRL----------VQQ-------LKQQTQN----RMK
LMADNYEDDH----L-------K-SSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLY--
---------IGHLTALCHDRDPLILRGLTPP-----------------------------
-----ASYHLDDDRAAWEKE-------LQKMTQEQLRDELEKGEKESAKLQEFANAILQQ
IADHCPDILEQVVNALEESS----------------------------
>gi|115749112|ref|XP_780607.2|	Strongylocentrotus purpuratus
---------------------MPMN-------------------------ES------GE
KILSKLGQKRK----------QQAAAQNAAAAAAAAGS----------------------
------------------------------------------------------------
---------------------------QGGATPQLTVS----------------------
YP-----TTRATQGGQP----------RQRVFTGTVTKLHDTF---------GFV-----
----------------DEDVFF----------QTNT-VKGT-------------------
-----MPKIGERVL----VEAT---Y-NASMPFKWNATRIQLL------NNPLEQQVPQA
QPQQQQQ-------------------QHHAAMKMQQI-KQMQQQQ--QQQPSRIESVSQQ
F--------KM---------------------------LKQSQQPLLKAPQAGNMMPTHS
Q----PPPPGLLGN-----------------------PP-------PLLQQPPPGVV---
---QQAPLLQGNAQAMQNLAGAYAHQGRTSQMGQQQAMGRRDFSSSGSRER---------
-------DRDRDRE------RERDRAQRE--RDREREREHRERERERERERRERERVRER
EKSPVTKRSRSPRRSKSPRRSPRRTKR--LVQR--------YCVQIPRFALDIPKSDVIE
LHKRYMNMY-------------------------IPSDFYNADFA-----WQDVFPIHRP
MSVAQPCTLHIM---HK-----------------EAPPPQGAATVIDP--PDANYSYCAK
VMLMTSVSQDE--LYEKCCARAQDSS--D-IREN----FQHPTRLINFLVGQKGKNEVMA
IGGPWSPSLDGA--DPVNDTSVL-IKTAI------------RTTKALAGIDL---TACTQ
WYRFLELSYYRPEEIHK-GRVIPARVETVVIFVPD--VWHILPTKVE-WESLAD---LYR
--------------KTL---SNKL-----------------AAVDSRDKKTEDPTPTQFL
ESEEPAAVKEEEEEEV---EEQEHQTPTN-----WKELDPKNM-KVNE------------
--------------------LRQELEIRGLNSKGLKSQLIARLTKMLKT-EQEMEDAEPA
---AMETDAATEN-----------------ASKEEPKDAPKEEE-----EEEKKRQRERE
KRDLESR---Y-TMPDGPVI---------LVHPSPIAKSGKFDCTQQSLSVLL---DYRV
E---DNKEHSFEVFLFAELFNEMLQRDFA--FNMYKAIFRAPEKKEE-----KKDEKKK-
-------DKKDEKEKKDEKKEERKDDKDEKKE--------DKKEE-----EPKAKRRKTE
EKDA----------DKEESKDKDEERKDEDIKEED---KDGEEEENDGRSNEDD-----A
DDDDKKKG--------------------------DKKSKDDKTKPRIKMETLDPHLLLSC
IYF---DQNH------------------------CGYILE---RDLEEILYT------I-
----GVHL----SR---AQVRKLLQKVVTRDCW---------------------SYRKLT
DGPK--KEKDDTTKAAEA--NNVPSDA----------DLS--------------KGNQMI
LD--------TMATSKKGSKGMAPDGL-------------TMVKYGGT-------VIDIA
NLLKQVQKADQ--ER---------SMAEKKIESLEKQIDTLKSKA-------STSEAT--
-V-------TNVSGELVDVQKRLTTS----------ERA-------LIGSS------TRS
KKLIDVIGTA----Q-------K-------------NLDEIML----------KFNEV--
---------LEEALLPSTSKVPEKV-----------------------------------
-----VEKVKEEAKVKTEAK---------VKTETKYAAKAEPKSPKVEK-----------
------------------------------------------------
>gi|91076266|ref|XP_967485.1|	Tribolium castaneum
-----------MGQFNNKN--PPWGRANNSPNIVN---------------QPSPLQQQIM
NQSALNNMNTSGMVQFQQQHQQQVFQNAMGLQQQNL-----GLGLQQMA-----------
--NNAMGAGLGSQLAS-----------------------------NQIFQQVGAVTYPN-
--------------PRGL---------NPTAFQTQNIS----------------------
AV-----PPVQNNSNVGT---------KQRVFTGTVTKVHDNF---------GFV-----
----------------DEDVFF----------QINACVKGS-------------------
-----NPTVGDRVL----VEAS---Y-NPTMPFKWNATRIQVL------PMSNQPSNRHS
NNSKN---------------------YNNSNANTY---NAVPPPN---------------
------------------------------------------------------------
-----DNSNGNFGR----------------------------------------NQR---
---------------------------------PKAVMGRGR-------ER---------
-------SRDRERD--------------DDEIERKRRREERMREREKEEKKSPL-----R
RRS----------------RSPKSRRRSRIVPR--------YMVQIPKIALDLSEADVLE
IRRRYANLY-------------------------IPSDFFYTHFR-----WVDAFPPDKP
FTMNKPSFFHIM---NK-----------------EVDPVVENDAVLEP--PDADYLFSAK
VMLMSMSGLDE--LYQKCCAMAEDKD--KRDRESEERDFVHPARLLNFLVGLRGKNETMA
IGGPWSPSLDGE--NPDKDPSVL-IKTAI------------RTCKALTGIDL---SSCTQ
WYRFVELYYRRSESTHK-GRAVPARVETVVLFLPD--VWSCVPTRLE-WDGLHQ---SYR
--------------KQL---ERRL-----------------KADLEIGGGGGGSE-----
-----------E-------PPSDKLEPTH-----YSQLDPKTM-VVSA------------
--------------------LRNELKARNINSKGLKSQLVARLAKALKV-EAEKAED---
-------PTKEIQ-----------------TEVDYDISADEKKI-----EAEEKKLDEKE
KALLEKR---Y-TLPEQQHI---------LVHPSRTAKSGKFDCTIMSLSLLL---DYRP
E---DTKEHSFEVSLFAELFNEMLMRDFG--FNIYRALYELPDK----------------
-------IKDEKKKRDDEKKSDDKNKKEDEKK-------KDEEKS-----EESEKKKKDD
KKSD----------DSEEDEEYDDE----------------------------------E
GKDKKKDK-------------------------------EKKKKERVKMFTKDKHLLLSF
IYF---DQTH------------------------CGYIFD---KDIEDLLYT------L-
----GLNL----SR---AQVRKLVGKVVTRDSL---------------------HYRKLT
DKPK--DNNE----------FIVIDD----------------------------LEKETN
LH--------DL-ALGETSACEESCYL-------------GLVTYRGA-------LVDVG
KLMSQLERSEK--AR---------LETESRMVSLKNENNKLSDKY-------NKSNST--
-I-------KYLNSDLKEYKEKLRTT----------EDA-------LSRIT------AYS
KLYQTTLLDI----R-------D-------------KIDPVLKSTSNSSKEEVAVKKD--
---------CE-------------------------------------------------
-----KDKKHDESKTRWEKE--------VKQEEVQEVEPVEAKKEA--------------
------------------------------------------------
>gi|114630793|ref|XP_001168562.	Pan troglodytes
-----------MAQFGGQKN-PPWA-TQFTATAVS---------------QPAAL---GV
QQPSLLGASPT-------IYTQQTALAAAGLTTQTP-A---NYQLTQTAALQQQ------
--AAAAAAALQQQYSQPQQALYSVQQQLQ---------QP-----QQTLLTQPAVALPT-
--------------SLSLS--------TPQPTAQITVS----------------------
YP-----TPRSSQQQTQPQ--------KQRVFTGVVTKLHDTF---------GFV-----
----------------DEDVFF----------QLSA-VKGK-------------------
-----TPQVGDRVL----VEAT---Y-NPNMPFKWNAQRIQTL------PNQNQSQTQPL
LKTPPAV-----------------L-QPIAPQTTFGV-QTQPQPQ--SLLQAQISAASIT
P---------L---------------------------LQTQPQPLLQQP----------
-----QQKAGLLQP-----------------------PV-------RIVSQPQPARR---
------------------------LDP------PSRFSGRND-RGDQVPNR---------
-------KDDRSRE-------------RE--RERRRSRE-RSPQRKRSRERSPR-----R
ERE----------------RSPRRVRR--VVPR--------YTVQFSKFSLDCPSCDMME
LRRRYQNLY-------------------------IPSDFFDAQFT-----WVDAFPLSRP
FQLGNYCNFYVM---HR-----------------EVESLEKNMAILDP--PDADHLYSAK
VMLMASPSMED--LYHKSCALAEDPQ--E-LRDG----FQHPARLVKFLVGMKGKDEAMA
IGGHWSPSLDGP--DPEKDPSVL-IKTAI------------RCCKALTGIDL---SVCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WETLSR---GYK
--------------QQL---VEKL-----------------QGERKEADGEQDEE-----
-----------EKDDG---EAKEISTPTH-----WSKLDPKTM-KVND------------
--------------------LRKELESRALSSKGLKSQLIARLTKQLKV-EEQKEEQKEL
-------EKSEKE-----------------EDEDDDRKSEDDKE-----EEERKRQEEIE
RQRRERR---Y-ILPDEPAI---------IVHPNWAAKSGKFDCSIMSLSVLL---DYRL
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYKSLLSLPEKEDK-----KEKDKKS-
-------KKDERKDKKEERDDETDEPKPKRRK-----SGDDKDKK-----EDRDERKKED
KRKD----------DSKDDDETEEDNNQDEYDPME---AEEAEDEEDDR-DEEEM----T
KRDDKRDI----------------------NRYCKERPSKDKEKEKTQMITINRDLLMAF
VYF---DQSH------------------------CGYLLE---KDLEEILYT------L-
----GLHL----SR---AQVKKLLNKVVLRESC---------------------FYRKLT
DTSK--DEEN----HEES--ESLQEDM---------------------------LGNRLL
LP--------TP-TVKQESKDVEEN-V-------------GLIVYNGA-------MVDVG
SLLQKLEKSEK--VR---------AEVEQKLQLLEEKTDEDEKTI-------LNLENS--
-N-------KSLSGELREVKKDLSQL----------QEN-------LKISE------NMN
LQFENQLNKT----I-------R-------------NLSTVMD----------EIHTV--
---------LK-------------------------------------------------
-----KDNVKNEDKDQKSKE---------------------NGASV--------------
------------------------------------------------
>gi|110764054|ref|XP_393382.3|	Apis mellifera
--------MSNLSPFGGGKN-PPWV-------------------------RNAGQ---GI
Q-----------------NIQQQMLGQAMGSIGGQPMV---QYQQQTQQVYQQS------
-----------LGLQQPNITMASMAT-LG----------------SNLPSGIAGQLYPQ-
--------------VATVS--------YPPPRALNTNA----------------------
FQPSVAGVPQQVQQNVPSS------STKQRVFTGTVTQVYDNF---------GFV-----
----------------DEDVFF----------QTNACVKGS-------------------
-----NPVVGDRVL----VEAS---Y-NPSMPFKWSATRIQVL------PMGNNNNNTN-
--------------------------TQQNNQNTRQQ-QQQSQPQ-----QNRTSGT---
--------------------------------------YNAVPPPA--------------
-----ENANNRFTT--------------------------------SATNANTASNR---
-------------------------NK------VGRVRERSP------------------
-------RERKNEE-------------EE--IERKRRREERIREREKKEERSPS-----R
TRR---------------SKSPRPRRRTRVVPR--------YMVQIPKIALDLPEADVLE
IRRRYQNMY-------------------------IPSDFFSTNFR-----WVDAFPPHMP
FALNKPCSFHVM---HK-----------------DVDPCSENTAVLEP--SDADYLFSAK
VMLISMPAMEE--IYKRCCGVSEDRD--P-DRD-----YVHPTRLINFLVGLRGKNETMA
IGGPWSPSLDGP--NPEKDPSVL-IRTAV------------RTCKALTGIDL---SSCTQ
WYRFLELYYRRAETTHKSGRVVPSRVETVILFLPD--VWSCVPIKLE-WDGLQL---SYK
--------------KQLERKLLRA-----------------ASSPDDLDAANDTD-----
-----------EAADD---PVPEKKDPTH-----YSELDPKSM-NVTE------------
--------------------LRQELAARNLNCKGLKSQLLARLMKAITS-EQAKEEGRQD
-----DIEENDKD-------------ISPPPKEEEDKKFKDIKD----HDEDRRKLCERE
RAALEKR---Y-TLPESSHI---------IVHPSRMAKSGKFDCTVMSLSVLL---DYRP
E---DTKEHSFEVSLFAELFNEMLMRDFG--FRIYRSLCSLPEKP---------------
-------KEKDEDKKKDKKDDKRDEKKDDKRK--------DDDKR-----CKKDERKDDK
RREG----------SKDKKDEKDAKNKVDDRDREK----EKNDDDDDDE-EDES-----D
DDDSIKDV-------------------------------------------------LSF
VYF---DQTH------------------------CGYIFD---KDIEELIYT------L-
----GLKL----SR---AQVRKLVQKVVTRDSL---------------------HYRKLT
DRSK--EDDLKDEKKDEK--EIDKTDS-------------IKIENEEEILRSLALGNKKL
LPVFVGSGPPSK-RVHREDAIIEQS--------DESIVSDGFVIYKGS-------LLDVE
KLVSQLKRSEK--AR---------LDTEERLMELQHELCIVNEKS-------TKQTNN--
-I-------KALSEDLKVYKDKLRNT----------DEK-------LKKVS------SEC
HTYLTAVKNM----Y-------HIAAKMMQSDTKKVEVVEIQD-EKVSEVNGSEIETK--
---------FKMDSRWGDNKVPI-------------------------------------
-----KKEFTETDKDKKYVNALLLNYISKKEIKNVLSDKTATGK----------------
------------------------------------------------
>gi|149689930|ref|XP_001503666.	Equus caballus
-----------MAQFGGQKN-PPWA-TQFTATAVS---------------QPAAL---GV
QQPSLLGASPT-------IYTQQTALAAAGLTTQTP-A---NYQLTQTAALQQQ------
--AAAAAAALQQQYSQPQQALYSVQQQLQ---------QP-----QQTLLTQPAVALPT-
--------------SLSLS--------TPQPAAQITVS----------------------
YP-----TPRSSQQQTQPQ--------KQRVFTGVVTKLHDTF---------GFV-----
----------------DEDVFF----------QLSA-VKGK-------------------
-----TPQVGDRVL----VEAT---Y-NPNMPFKWNAQRIQTL------PNQNQSQTQPL
LKTPPAV-----------------L-QPIAPQTTFGV-QAQPQPQ--SLLQAQISAASIT
P---------L---------------------------LQTQPQPLLQQP----------
-----QQKAGLLQP-----------------------PV-------RIVSQPQPARR---
------------------------LDP------PSRFSGRND-RGDQVPNR---------
-------KDDRSRE-------------RE--RERRRSRE-RSPQRKRSRERSPR-----R
ERE----------------RSPRRVRR--VVPR--------YTVQFSKFSLDCPSCDMME
LRRRYQNLY-------------------------IPSDFFDAQFT-----WVDAFPLSRP
FQLGNYCNFYVM---HR-----------------EVESLEKNMAILDP--PDADHLYSAK
VMLMASPSMED--LYHKSCALAEDPQ--E-LRDG----FQHPARLVKFLVGMKGKDEAMA
IGGHWSPSLDGP--DPEKDPSVL-IKTAI------------RCCKALTGIDL---SVCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WETLSR---GYK
--------------QQL---VEKL-----------------QGERKEADGEQDEE-----
-----------EKDDG---EAKEISTPTH-----WSKLDPKTM-KVND------------
--------------------LRKELESRALSSKGLKSQLIARLTKQLKV-EEQKEEQKEL
-------EKSEKE-----------------EEEEDDRKSEDDKE-----EEERKRQEEME
RQRRERR---Y-ILPDEPAI---------IVHPNWAAKSGKFDCSIMSLSVLL---DYRL
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYKSLLSLPEKEDK-----KEKEKKS-
-------KKDERKDKKEERDDETDEPKPKRRK-----SGDDKDKK-----EDRDERKKED
KRKD----------DSKDDDETEEDNIQDEYDPME---AEEAEDEEDDR-DEEEI----N
KRDDKRDV----------------------NKYCKERPSKDKEKEKTQMITINRDLLMAF
VYF---DQSH------------------------CGYLLE---KDLEEILYT------L-
----GLHL----SR---AQVKKLLNKVVLRESC---------------------FYRKLT
DTSK--DEEN----HEES--EALQEDM---------------------------LGNRLL
LP--------TP-VVKQESKDVEEN-V-------------GLIVYNGA-------MVDVG
SLLQKLEKSEK--VR---------AEVEQKLQLLEEKTDEDEKTI-------LNLENS--
-N-------KSLSGELREVKKDLSQL----------QEN-------LKISE------NMN
LQFENQLNKT----I-------R-------------NLSTVMD----------EIHTV--
---------LK-------------------------------------------------
-----KDNVKNEDKDQKSKE---------------------IGTSV--------------
------------------------------------------------
>gi|148229467|ref|NP_001090254.	Xenopus laevis
-----------MAQFGGQKNPPPWA-TQFTATAVS---------------QPGPL---AV
QQSSLLGASPT-------IYTQQSALAAAGLASPSP-A---NYQLSQTAALQQQ----AA
AAAAAAAAALQQQYTQPQQTIYSVQQQLQ---------PP-----PQAILTQPAVALPT-
--------------SLALS--------TPQQAAQITVS----------------------
YP-----TPRSNQQQTQPQ--------KQRVFTGVVTKLHETF---------GFV-----
----------------DEDVFF----------QLTA-VKGK-------------------
-----SPQAGDRVL----VEAT---Y-NPNMPFKWNAQRIQTL------PNQNPASAQSL
IKNPAAV-----------------M-QPVAQPTAYAV-QTQPPPQAQTLLQAQISAATLT
P---------L---------------------------LQTQTSPLLQQP----------
-----QQKAGLLQT-----------------------PV-------RIVSQPQPVRR---
------------------------IEP------PSRFSVRND-RGDSILSR---------
-------KDDRNRE-------------RE--RERRRSRD-RSPQRKRSRERSPR-----R
ERE----------------RSPRRPRR--VVPR--------YTVQISKFCLDCPGCDTME
LRRRYQNLY-------------------------IPSDFFDAQFT-----WVDAFPISRP
FQLGNYSNFYIM---HK-----------------EVDPLEKNTAIVDP--PDADHTYSAK
VMLLASPSLEE--LYHKSCALAEDPI--E-VREG----FQHPARLIKFLVGMKGKDEAMA
IGGHWSPSLDGP--NPDKDPSVL-IRTAV------------RCCKALTGIEL---SLCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WENLCH---GYK
--------------QQL---VDKL-----------------QGDRKEADGEQEEE-----
-----------DKEDG---DAKEISTPTH-----WSKLDPKIM-KVND------------
--------------------LRKELESRTLSSKGLKSQLIARLTKQLRI-EEQKEEQKEL
-------EKCEKE-----------------EEEEEERKSEDDKE-----EEERKRQEELE
RQRREKR---Y-MLPDEPAI---------IVHPNWSAKNGKFDCSIMSLSVLL---DYRI
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYRELLALPEKEEK-----KDKEKKC-
-------KKEDKRERKEDKDDD-DEPKPKRRK-----SSDDKIKL-----EEKEERKRDD
RRKE----------DYREEDDPDYEN-QDDYEPIA---AEEDDGDYDDREDDDDDSSSKD
KREDKRDG----------------------NRYSKERQSKDKEKDKKQMVTVNRDLLMAF
VYF---DQSH------------------------CGYLLE---KDLEEILYT------L-
----GLHL----SR---AQVKKLFTKILLKESL---------------------LYRKLT
DTAT--EDGS----HEET--DPLHNDI---------------------------LGNCSL
LP--------SK-AVRTGLSTVEDKG--------------GLIVYKGA-------MVDVG
SLLQKLEKSEK--TR---------TELEHRLQTLESKTEEDEKTI-------SQLEAS--
-N-------RNLSEELKQTKDDVGHL----------KDS-------LKAAE------DTR
SLYEDQLTNT----I-------K-------------NLSAAMG----------EIQVV--
---------LN-------------------------------------------------
-----KNPSTTED--QKSKE---------------------NGSS---------------
------------------------------------------------
>gi|47219799|emb|CAG03426.1|	Tetraodon nigroviridis
---------------QGFIC-PQCMKSHNSAEELF---------------KHYDLFHDTG
ELPAHVAPTREDLT----MLRQEVQDLHASLKEERWFSGELKKELDKVQGHLKQ------
---VIPFRSLERKLNEAETEKFNIKQ-------------------MKDLFEQKAAQLAT-
--------------EIVDLKSRYDEEKSLRDAADHKLA----------------------
-------NLNEQLQREKQE--------KERLLTELLQRP-------------GVE-----
----------------DVEVLQKELVQVQT--LMDSMTRER-------------------
-----EEESERLKNHYEQLQAN---YTNSEMTIAQLKAELEKG------PQEVAVYTKEI
HELRSSL-------------------NSLQQQSQSLSEKLEQKEK--DYLQLEEMLAKEK
G-------------------------------------SKKKAQDGLKER----------
-----DQEVQELQA--------------------------------RLAGAETSLQK---
------------------------AQAELQERTEEVSKLRSE-MGELEVKHAELKVERKQ
LEQLREEKESHGAQ-------------QQTEIGQLHAKLLETERQLGEVEGRLK-----E
QRQ----------------LSGEKLKD--------------REQQAADLQLKLSRTEEQL
KESATKNTD-------------------------LQHQLEKAKQQ-----HQELQVLQQN
TNGKLREAQNDL---EQ-----------------VLRQIGDKDQKIQN--LEALLQKSKD
IVSQLEAERDD--LCAKIQAGEGETAVLNQLKDKNQALQGQVTQLTDKLKNQSESNKQAQ
DNLHKQVQEQKTLLRSAQDRAHT-METTVT-----------ELTAQLTDSK----EKVSQ
LDAQLKAKTEMLLSAEA-AKAA---------------QKANMENSLE-TAQHAL---QDK
--------------QQE---LNKV-----------------QKKIEEQTQSLKEK-REQC
--TQLETNVKEYKDKLLASEQRTEQLQSL-----NKRLES----QLGE------------
--------------------LQTAHEQVQQQVQKLQKESTEMKQKAKEL-QHSLETEKAG
-------KLQNLL-----------------ADLQKAQQEKEAHK-----KEIGSLQENLG
KTKKALKESQN-VLDAERKS--HQSAVEERDKSNQKARQELLKKNEALTKTMN---ESKD
Q---LEQMREAEKSLKVQLTSVEQQQVKA--QEALKQKQNQLEKLQA-----QLQTVEG-
-------SLEVETKKLKGQIAELQESGVKKAK-----EEKQLRAQVAGLSEELASEKRRT
TEVQ----------KALEQSQESQSKLQSDLYGKE---TEVSALHQDLR-ACEE-----K
LKLAQEEL----------------------AGNQTHQTGLEAQIQELQVSRGSLEEELG-
------KLEH------------------------KLQQRE---QTLKDSEKH------QT
QVKEELKR----EKSKAEELNKLKNDLENNSSR---------------------LAADLK
ALKE--KSDKELGNLQEAKLLLIQQKLELQTQVEAAQGDLEQERKEHQSTKDGSLRRKEQ
LL--------AQIKDVQDQLSSEKKAREEQAKRGEEAEARTSAQVTAL-------NENVA
TLKREWQGSQR--RV---------GELEKQTDDLRGEIAVLEATVQNNQDERRALLER--
-C-------VKGEGEIEKLQAKVVEL----------RRK-------LEDTTA-----AMQ
ELGRENQSLQ----I-------KQSQSLTRKWAEDHEVQSCMGCGKGFSVTVRKVGGA--
---------PKSPLSPISPSDRRLFSSPWLFSTTADTAGTFSVPSVRRGTPSHRPPKSQS
GCVRPASRSSRADLPPPPPP-----LLPQQAHPPSPPTPAGRGQRVFVIHVHYSGEAPRG
VLHAGSRLWVAPPPNTQESCD---------------------------
>gi|73967056|ref|XP_537750.2|	Canis familiaris
------MRVKTEEQIAAEEA---WY-ETEKVWLVH---------------KDGFSLGSQL
KSEELSLPEGK-------VRVKLDHDGAILDVDEDDVE---KANAPSCDRLEDL------
---------ASLVYLNESSVLHTLRQRYGASLLHTYA--------GPSLLVLSPRGAPAV
YSEK----------VMHMFKGCRREDMAPHIYAVAQTA----------------------
YR-----AMLMSRQDQSVILLGSSGSGKTTSCQHLVQYLATIA---------GTS-----
----------------GNKVFSVEKWQALY--SLLE-AFGN-------------------
-----SPTIMNGNA----TRFS---Q-ILSLDFD-QAGQVASASIQTMLLEKLRVARRPA
SEATFNVFYYLLACADGTLRTELHL-NHLAENNVFGI-VPLAKPE-----EKQKAAQQFS
K-------------------------------------LQTAMKVLGISP----------
---DEQKACWLILA-----------------------AIYHLGAAGATKEAAEAGRK---
---QFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGCTLQRSTSFRQGPEESSLGDGTGP
KLTALECLEGMASGLYSELFTLLVSLVNRALKSSQHSLC-SMMIVDTPGFQNPE-----Q
GGSARGASFEELCHNYAQDRLQRLFHERTFVQELERYKEENIELAFDDLEPATDDSVAAV
DQASHQSLVRSLARTDEARGLLWLLEEEALVPGATEDALLERLFSYYGPQEGDKKGQRPL
LRSSKPHHFLLG---HSHGTNWVEYNVSGWLSYTKQNPATQNAPRLL---QDSQKKIISN
LFLGRAGGTTV--LSGSIAGLEGGSQ--LALRRA----TSMRKTFTTGMAAVKKKSLCIQ
IKLQVDALIDTI--KKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEA
GLLQLDVPLLRAQLR---GSRLLDAMRMYRQGYPDHMVFSEFRRRFD-VLAPHL---TKK
HGRNYIVMDERRAVEEL---LESLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNL
TLFQAACRGYLARQHFKKKKIQDLAIRCV-----QKNIKKNKG--VKD------------
------------WAWWKLFTTVRPLIEVQLSEEQIRSKDEEIQQLRSKL-EKVEKERNEL
RLSNDRLETRISE---------------LTSELTDERNTGESASQLLDAEAAERLRAEKE
MKELQTQ---YDALKKQMEVMEM------EVMEARLIRAAEINGEVDDDDTGG---EWRL
KYERAMREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADIDESQRALQQLKKKCQ
RLTA---ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQ-----REKLQREKLQ
REKDTLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE---AELQDISSQESKDEASLA---K
VKKQLRDL----------------------EAKVKDQEEELDEQAGTIQMLEQAKLRLEM
EMERM-RQTHSKEVESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE------KR
ELESKLTTLSEQVSQRDLESEKRLRKDLKRTKALLADAQIMLDHLKNNAP----SKREIA
QLKNQLEESEFTCAAAVKARKAMEVEM---------------------EDLHLQIDDIAK
AK--------TALEEQLSRLQREKNEIQSRLEEDQEDMNELMKKHKAAVAQASRDLAQMN
DLQAQLEEANK--EK---------QELQEKLQALQSQVEFLEQSMVDKSLV-SRQEAK--
-I-------RELETRLEFERTQVKRLESLASRLKENMEK-------LTEER------DQR
TAAENREKEQ----N-------K--RLQRQLRDTKEEMGELARKEAEASRKKHELEMD--
---------LESLEAANQSLQADLKLAFKRIGDLQAAI----------------------
-----EDEMESDENEDLITSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSS
SPTSYWKSLAPDRSDDEHDPLDSTSRLRYSHNYLSDSDTEAKPTETNA
>gi|109089548|ref|XP_001083179.	Macaca mulatta
-----------MAQFGGQKN-PPWA-TQFTATAVS---------------QPAAL---GV
QQPSLLGASPT-------IYTQQTALAAAGLTTQTP-A---NYQLTQTAALQQQ------
--AAAAAAALQQQYSQPQQALYSVQQQLQ---------QP-----QQTLLTQPAVALPT-
--------------SLSLS--------TPQPTAQITVS----------------------
YP-----TPRSSQQQTQPQ--------KQRVFTGVVTKLHDTF---------GFV-----
----------------DEDVFF----------QLSA-VKGK-------------------
-----TPQVGDRVL----VEAT---Y-NPNMPFKWNAQRIQTL------PNQNQSQTQPL
LKTPPAV-----------------L-QPIAPQTTFGV-QTQPQPQ--SLLQAQISAASIT
P---------L---------------------------LQTQPQPLLQQP----------
-----QQKAGLLQP-----------------------PV-------RIVSQPQPARR---
------------------------LDP------PSRFSGRND-RGDQVPNR---------
-------KDDRSRE-------------RE--RERRRSRE-RSPQRKRSRERSPR-----R
ERE----------------RSPRRVRR--VVPR--------YTVQFSKFSLDCPSCDMME
LRRRYQNLY-------------------------IPSDFFDAQFT-----WVDAFPLSRP
FQLGNYCNFYVM---HR-----------------EVESLEKNMAILDP--PDADHLYSAK
VMLMASPSMED--LYHKSCALAEDPQ--E-LRDG----FQHPARLVKFLVGMKGKDEAMA
IGGHWSPSLDGP--DPEKDPSVL-IKTAI------------RCCKALTGIDL---SVCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WETLSR---GYK
--------------QQL---VEKL-----------------QGERKEADGEQDEE-----
-----------EKDDG---EAKEISTPTH-----WSKLDPKTM-KVND------------
--------------------LRKELESRALSSKGLKSQLIARLTKQLKV-EEQKEEQKEL
-------EKSEKE-----------------EDEEDDRKSEDDKE-----EEERKRQEEME
RQRRERR---Y-ILPDEPAI---------IVHPNWAAKSGKFDCSIMSLSVLL---DYRL
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYKSLLSLPEKEDK-----KEKDKKS-
-------KKDERKDKKEERDDETDEPKPKRRK-----SGDDKDKK-----EDRDERKKED
KRKD----------DSKDDDETEEDNNQDEYDPME---AEEAEDEEDDR-DEEEM----T
KRDDKRDI----------------------NRYCKERPSKDKEKEKTQMITVNRDLLMAF
VYF---DQSH------------------------CGYLLE---KDLEEILYT------L-
----GLHL----SR---AQVKKLLNKVVLRESC---------------------FYRKLT
DTSK--DEEN----HEES--ESLQEDM---------------------------LGNRLL
LP--------TP-TVKQESKDVEEN-V-------------GLIVYNGA-------MVDVG
SLLQKLEKSEK--VR---------AEVEQKLQLLEEKTDEDEKTI-------LNLENS--
-N-------KSLSGELREVKKDLSQL----------QEN-------LKISE------NMN
LQFENQLNKT----I-------R-------------NLSTVMD----------EIHTV--
---------LK-------------------------------------------------
-----KDNVKNEDKDQKSKE---------------------NGASV--------------
------------------------------------------------
>gi|156550661|ref|XP_001605185.	Nasonia vitripennis
--------MSNISPFGGGKN-PPWV-------------------------RNAGQ---GI
Q-----------------NIQQQMLGQAMGGMGGQPMV---QYQQPNQQVYQQS------
-------LGLQQVSKHPNITMASMAT-LG----------------SNLPSGIAGQLYPQ-
--------------VATVS--------YPTPRTLNANA----------------------
FTQSVAGVTQQVQQNVPPS------STKQRVFTGTVTKVHDNF---------GFV-----
----------------DEDVFF----------QTNACAKGS-------------------
-----NPAVGDRVL----VEAS---Y-NPSMPFKWNATRIQVL------AMGNNNNSANA
QPPAPTN-------------------RPNQPTRTSGNYNAVPPPN--ENANNRFSANNTS
T---------T-------------------------------------------------
----------------------------------------------AVANRNKAARV---
----------------------RERSP---------------------------------
-------RDRRNDD-------------EE--VERKRRREERIREREKKEERSPS-----R
TRR---------------SKSPRPRRRARVVPR--------YMVQIPKIALDLPEADVLE
IKRRYQNMY-------------------------IPSDFFSTNFR-----WVDAFPPHMP
FTLNKPCSFHVM---HK-----------------DVDSCIENTAVLEP--PDADYLFSAK
VMLISMPQMEE--IYKRCCGVTEDRD--N-DRD-----YIHPTRLINFLVGLRGKNETMA
IGGPWSPSLDGP--NPDKDPSVL-IKTAI------------RTCKALTGIDL---SNCTQ
WYRFLELYYRRAETTHKSGRVVPSRVETVILFLPD--VWRCVPTRLE-WDGLHL---SYK
--------------KQL---ERKL-----------------LRASESAEPEAAPP-----
-----------AAADD---AVPEKKDPTH-----YSELDPKNM-NVND------------
--------------------LRLELVARNLNSKGLKSQLQARLSKAIKS-EQAKEEGRQD
-------EPEENDK--ES-------MPSPKDDPKDDKRSKDSKE----NDDDKKKLYDRE
RAMLEKR---Y-NLPEASHI---------IVHPSRTAKSGKFDCTVMSLSVLL---DYRP
E---DTKEHSFEVSLFAELFNEMLMRDFG--FRIYRALCNLPEKPKE-----KEEDKKK-
-------DKKDDKKKDDDRKSKKDDKRDDKKS-------DSKDKK-----DDKDAKSKDE
KDKD----------KNDDEDDEDDDDSEVSFSKLDIVLNKFYENTNATLLKDDD-----S
LKDGKKDR------------------------------DKDGKKKRVKLYTFDPYLLLSF
VYF---DQTH------------------------CGYIFD---KDIEELIYT------L-
----GLNL----SR---AQVRKLVQKVVTRDSL---------------------HYRKLT
DKTK--DEDS----KKDD--EKADENV---------------------------LGNKKL
LPVFVGSGPASK-RARRENSSADQD--------EGESVPEGFIMFKGS-------LLDIE
KLVSQLKRSEN--AR---------VDTETRMMEIQRELSVVSEKS-------TKQSNT--
-I-------KDLSDDLKMYKDRLRNA----------DDK-------LKKVT------TES
HSYFTSIKSI----Y-------HIASKSIQSDTKRVEIVEIQDEKGTTEVNGAQLEAK--
---------SKSDTRWSDSKVTV-------------------------------------
-----KKELNECEKDKKCDN------------KVIIKKEIAEDEKERK------------
------------------------------------------------
>gi|28574245|ref|NP_724047.2|	Drosophila melanogaster
--------MSDDTSASGGTS-APFP-SPVTADPEPGATASKLPGPIRSNIPTPATSGTGI
PQPSKMKAPSS--------FGSTGSVSKIGRPCCNHTTPKSGPPPREATSMSRE------
--SDDNLSSINSAYTDNSSAVLTANTEQF------------IIGQRVWLGGTRPGQIAF-
--IGDTHFAAGEWAGVVLD--------EPNGKNDGCVSGKRYFQCEPKRGIFSRLTRLTT
YPLAGAQTPTSPLAKSSPD--------RSRTVSPTASIRSSMLRSPGIGGKNGMAVGDRV
IVSSGFGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPI
AKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMRMN-----AQRKSSTPVKPI
LATPKSQFSMQDLLREKQQHVEKLMVERDLDREDAQN-QALQLQKNINELKARIVELESA
LDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSAT----------
-----PSLQSILPP---DLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQR---
------------------------LRENVKYLNEQIATLQSELVSKDEALEKFSLSECG-
-------IENLRRE-------------LELLKEENEKQA-QEAQAEFTRKLAEK-----S
VEVLRLSSELQNLKATSDSLESERVNK-------------TDECEILQTEVRMRDEQIRE
LNQQLDEVTTQLNVQK------------------ADSSALDDMLRLQKEGTEEKSTLLEK
TEKELVQSKEQAAKTLN-----------------DKEQLEKQISDLKQLAEQEKLVREMT
ENAINQIQLEKESIEQQLALKQNELE--DFQKKQ----SESEVHLQEIKAQNTQKDFELV
ESGESLKKLQQQ--LEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQ----SKSAE
SESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHD--EISQLKSQAE-ETQSEL---KST
--------------QSN---LEAK-----------------SKQLEAANGSLEEE-AKKS
--GHLLEQITKLKSEV---GETQAALSSC-----HTDVESKTK-QLEAANAALEKVNKEY
AESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKL-SKFSDEIATGHKELTSKADA
----WSQEMLQKE-----------------KELQELRQQLQDSQ-----DSQTKLKAEGE
RKEKSFEESIK-NLQEEVTK---------AKTENLELSTGT-QTTIKDLQERL---EITN
A---ELQHKEKMASEDAQKIADLKTLVEA--IQVANANISATNAELST----VLEVLQA-
-------EKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETH-----LQLDERQKKF
EELE----------EKLKQAQQSEQKLQQESQTSK---EKLTEIQQSLQ-ELQ------D
SVKQKEEL----------------------VQNLEEKVRESSSIIEAQNTKLNESNV---
------QLEN------------------------KTSCLK---ETQDQLLESQKKEKQLQ
EEAAKLSGELQQVQEANGDIKDSLVKVEELVKV---------------------LEEKLQ
AATSQLDAQQATNKELQELLVKSQENE------------------------GNLQGESLA
VT--------EK-LQQLEQANGELKEA-------LCQKENGLKELQGK-------LDESN
TVLESQKKSHNEIQD-------KLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQ
QKQLLLEKGNEFDTQLAEYQKVIDEM----------DDAASVKSALLEQLQNRVAELETA
LRQANDAQKTA--YLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDI
ETSLAKINFLNSIIADMQQKNDALKAKVQTLETLPMDF----------------------
-----TKPHAFDALTKRKPAPRLFCDICDEFDQHDTEDCPIQGSEDQDYSTPSSESNNNE
KERKLPAPRKYCDSCEVFGHDTSECADDETY-----------------
>gi|125832922|ref|XP_696330.2|	Danio rerio
-------MERLLHSPGRTRDEHRYQ-TPRPSSQLL---------------SRSAF---SF
GSPVPLRGNET--------LSEFAAKPADSFDYSSKYAGAMNLRKISEKELLQG------
---------LNDRFAGFIEKVHHLEN-------------------QNRALEKEIEAIRL-
---------------------------RAKSSTSLSKE----------------------
YE-----SELSSLREQVHE-----MGLQKHQIEINRQNLEDEF---------NTL-----
----------------RE--------------KYERETRGR-------------------
------------------VDAE-----DGISVLK-KCINDAYL------AKQEMDRKARA
LQEEIGF-----------------L-KKNHESEVAEM-MAQIEE---GHVTAEISDFSRS
D-------------------------------------VTAALRGIRMQL----------
-----EGHSGSDT---------------------------------RYAEERFRAQF---
----------------------------------ARLTKAAEVNREALMAT---------
-------KAEINEH-----------------RRQLQSKNIELDSMKGVREGLER-----Q
LYD----------------LEQRHNAEIHHYQ---------DTIRELEFELKNAKYDMSS
HLREYQDLL-------------------------------NVKMAL----DAEIYS----
---------------YR-----------------KLLEGEESRQGGAP--RKAEPQYKFV
EEIITETTREDVEISDTGSEKSGEGR--VDDKPD----EESSEKDAETEQEAEDPEEPAV
VNGTEEAETENE--DKPSDE-----------------------------------KEDEP
VEESPKGQKDADSE----------------------------PTRESMPTETDIDEVGKD
--------------EETGTKGTEH-----------------KDQKVDTKGKEAPE-EEDV
-----------KKTDE---PIKEKELPKTEEREMPEKSEDKPS-----------------
----------------------LEHKTLVNTKPNGETEVTSPKTEVAKI-SSQDSATAKS
---------PEKE-----------------KETSPVQPVEKDTP-----KPDKHDLDKLT
TEEKTSA-------------------------------------KIAVVEEKS---EKDL
E---DNNKQPEKPVEKKETESKEQKSEES--TKDSKAAKVIDDVKTE-----KDDGIKS-
-------NKAE-----KEKVEEQSKKQEDSKT-----DGNVETVP----IETTKEKETEK
KQED----------IPKEKSKTEKDDKSD-----S---AGNANTEKDDR-AAPK-----E
TEKTQQDL----------------------PKVAEGKSQPEKLQEKQE------DSKSDY
VKAELAKPKE------------------------TEKTQEDLPKAAEEKTQP------EK
SQTQENSK----SDSAGSTKTKKLESDATRETG-----------------------KTQE
DLPKAAEEKTQPEKSQTQ--ENSKSDS---------------------------AGSAKT
KK--------LESDATKETGKTQENLPKVTEEKSQPEKPQKQENNKSD-------AVKPE
NIEHPKPTETKDNSK----------GMEPKLEEVKSEIKDDAKSDSVDI---NKTETT--
-K-------PAIPKETEEKRKKEDSE------SVSAAES-------VKTSK------DEA
KTKEKAVDETQ--ST-------QSPKTQEPSSEAKPEQKDTNEGKGKMPEKAEEVNTV--
---------TTKGSKDVKGEDTVPKDKAGEVKA---------------------------
-----PAATKTEDKTVEKSD-------------------QVKGTEKTDSVDTKAS-----
------------------------------------------------
>gi|115496588|ref|NP_001070000.	Bos taurus
-----------MAQFGGQKN-PPWA-TQFTATAVS---------------QPAAL---GV
QQPSLLGASPT-------IYTQQTALAAAGLTTQTP-A---NYQLTQTAALQQQ------
--AAAAAAALQQQYSQPQQALYSVQQQLQ---------QP-----QQTLLTQPAVGLPT-
--------------SLSLS--------TPQPAAQITVS----------------------
YP-----TPRSSQQQTQPQ--------KQRVFTGAVTKLHDTF---------GFV-----
----------------DEDVFF----------QLSA-VKGK-------------------
-----TPQVGDRVL----VEAT---Y-NPNMPFKWNAQRIQTL------PNQNQSQTQPL
LKTPPAV-----------------L-QPIAPQTTFGV-QAQPQPQ--SLLQAQISAASIT
P---------L---------------------------LQTQPQPLLQQP----------
-----QQKAGLLQP-----------------------PV-------RIVSQPQPARR---
------------------------LDP------PSRFSGRND-RGDQVPNR---------
-------KDDRSRE-------------RE--RERRRSRE-RSPQRKRSRERSPR-----R
ERE----------------RSPRRVRR--VVPR--------YTVQFSKFSLDCPSCDMME
LRRRYQNLY-------------------------IPSDFFDAQFT-----WVDAFPLSRP
FQLGNYCNFYVM---HR-----------------EVESLEKNMAILDP--PDADHLYSAK
VMLMASPSMED--LYHKSCALAEDPQ--E-LRDG----FQHPARLVKFLVGMKGKDEAMA
IGGHWSPSLDGP--DPEKDPFVL-IKTAI------------RCCKALTGIDL---SVCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WETLSR---GYK
--------------QQL---VEKL-----------------QGERKEADGEQDEE-----
-----------EKDDG---EAKEISTPTH-----WSKLDPKTM-KVND------------
--------------------LRKELESRALSSKGLKSQLIARLTKQLKV-EEQKEEQKEL
-------EKSEKE-----------------EEEEDDRKSEDDKE-----EEERKRQEELE
RQRRERR---Y-ILPDEPAI---------VVHPNWAAKSGKFDCSIMSLSVLL---DYRL
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYKSLLSLPEKEDK-----KEKEKKS-
-------KKDERKDKKEERDDETDEPKPKRRK-----SGDDKDKK-----EDRDERKKED
KRKD----------DSKDDDETEEDNNQDEYDPME---AEEAEDEEDDR-DEEE-----N
KRDDKRDI----------------------NRYCKERPSKDKEKEKTQMITINRDLLMAF
VYF---DQSH------------------------CGYLLE---KDLEEIFYT------L-
----GLHL----SR---AQVKKLLNKVVLRESC---------------------FYRKLT
DTSK--DEEN----HEES--EALQEDM---------------------------LGNRLL
LP--------TP-VVKQESKDVEEN-V-------------GLIVYNGA-------MVDVG
SLLQKLEKSEK--VR---------AEVEQKLQLLEEKTDKDEKTI-------LNLEIS--
-N-------KNLSGELREVKKDLSQL----------QEN-------LKISE------NMN
LQFENQLNKT----I-------R-------------NLSTVMD----------EIHTV--
---------LK-------------------------------------------------
-----KDNGKNEDKDQKSKE---------------------NGASV--------------
------------------------------------------------
>gi|125852825|ref|XP_001336523.	Danio rerio
MLKTMASSKAALVKRLSESR-LKWK-NKKKKKAEN---------------QT------EV
KKPPKSAKDPV---------SNSDSKAATPHKRETKSE---SVTLKDDKNTETR------
-PTRSRDSSAKTSTDKRRTDKVVPARKMT----------------SVKTITTGWRRLPS-
--------------SVILA--------RRMDAAKTLSA----------------------
HR-----KHVLNRKIISTA--------KKRIDAVNHRKPSRIT---------RST-----
----------------ADPI------------EATDDVTAK-------------------
-----PLALKRKRK----QNDS---EVKGDAPISIPATDISAS------STPTGSKRRRL
--TEPEK-----------------K-SKDDEKELKEN-EAQSKEK--NEVEQKIEKQNEV
E---------K---------------------------SNADKNKMMEKK----------
-----NQAE-------------------------------------KIVAENETENK---
-------------------------GA------KKKESEKSD-AEKEKSEK---------
-------KETKKIE-----------------TERKEARNSEAESKEPCKNDSEK-----K
EAE----------------RIETRKSE--------------SEVLVAKNK----ESEKRE
TRKSESEM------------------------------------------KEARKNESKK
QEARKSESE------KR-----------------ETRKSESEMKEARK--NESE------
----MKEARKS--ESEKRETRKSESE--MIEARKNESEMKEARKSESERRETKNSEAEIK
EARKNESEIEAI--RSNSEKRET------------------RKSDSEMEAKNNESEKREA
GKSESEMKEARKNESEK----------------------KEARKRETRKSESDM---KEA
--------------KRK---ETRK-----------------SESEIKVAKDNDSE-KRET
--TKNESEIE-AKNKESEKREAGKSESEI-----KEARKNESE-KEEA------------
--------------------RKRETRKSESDMKEAKRKEARKNESEIKVAKDNDSEKRET
RQNEFEIETKNNE-----------------SEKRETRKSESEMK-----EARKTDSEIIE
AKKNESEKESKRDESEKRET---------RKNESEMKEARKNESEKRAIRNE----SEKR
E---TKSQSEIKESEKREARNIESEKKEA--KKIDSEMKQARKNESE-----KKEARKS-
--------ESEKKEAERVETRKTESEKKEVRK-----SESEKKEA-----ERKLERKSES
ERK-----------EAKKSESENKEARGNESEKKG---ARRSESEKKEARQSES-----E
KKEARRSE----------------------SEKRENRRSESEKKEARRNESEKRETRSES
E-----KRET------------------------RRNESE---KREPRWRES------EK
KETRRRESEKKETRRSESEKKEPRSESKKKEARRSESEKKEARRSE--------FEKKEA
RRSEFEKKEARMSESDKK--EAKRNES------------------EKKEARRSEFEKKEA
RR--------SE-FEKKEARMSESEKARRSEFEKKEARRNESEKKDAR-------RNESE
KKEARRNESEKKEAR---------SESEKKEARRNESEKNEGRRN-------ESEKKE--
-E-------RRIESEKKEARKNKSEK----------EAR-------RSDSE-----LKEA
RRKESELKEA----R-------RNESVKSDAEKDAVEKNKAEKNKLPEKRKEINVEER--
---------RETMTKPKQTKSCAPVSSDETQE----------------------------
-----EKKPRDEERCKILAEKRQSVLKSLQGLVTSTRGKTPSGSEQTTETKEPRKERNHR
LKQPAEDEKKDTEKRKEQEKRNTE------------------------
>gi|109510125|ref|XP_001058883.	Rattus norvegicus
-----------MAQFGGQKN-PPWA-TQFTATAVS---------------QPAAL---GV
QQPSLLGASPT-------IYTQQTALAAAGLTTQTP-A---NYQLTQTAALQQQ------
-----AAAVLQQQYSQPQQALYSVQQQLQ---------QP-----QQTILTQPAVALPT-
--------------SLSLS--------TPQPAAQITVS----------------------
YP-----TPRSSQQQTQPQ--------KQRVFTGVVTKLHDTF---------GFV-----
----------------DEDVFF----------QLGA-VKGK-------------------
-----TPQVGDRVL----VEAT---Y-NPNMPFKWNAQRIQTL------PNQNQSQTQPL
LKTPTAV-----------------I-QPIVPQTTFGV-QAQPQPQ--SLLQAQISAASIT
P---------L---------------------------LQTQPQPLLQQP----------
-----QQKAGLLQP-----------------------PV-------RIVSQPQPARR---
------------------------LDP------PSRFSGRND-RGDQVPNR---------
-------KDDRSRE-------------RD--RERRRSRE-RSPQRKRSRERSPR-----R
ERE----------------RSPRRVRR--VVPR--------YTVQFSKFSLDCPSCDMME
LRRRYQNLY-------------------------IPSDFFDAQFT-----WVDAFPLSRP
FQLGNYCNFYVM---HR-----------------EVESLEKNVAVLDP--PDADHLYSAK
VMLMASPSMED--LYHKSCALAEDPQ--D-LRDG----FQHPARLVKFLVGMKGKDEAMA
IGGHWSPSLDGP--NPEKDPSVL-IKTAI------------RCCKALTGIDL---SVCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WETLSR---GYK
--------------QQL---VEKL-----------------QGERKKADGEQDEE-----
-----------EKDDG---EVKEIATPTH-----WSKLDPKAM-KVND------------
--------------------LRKELESRALSSKGLKSQLIARLTKQLKI-EEQKEEQKEL
-------EKSEKE-----------------EEDEDDKKSEDDKE-----EEERKRQEEVE
RQRQERR---Y-ILPDEPAI---------IVHPNWAAKSGKFDCSIMSLSVLL---DYRL
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYKSLLSLPEKEDK-----KDKEKKS-
-------KKEERKDKKEEREDDIDEPKPKRRK-----SGDDKDKK-----EDRDERKKEE
KRKD----------DSKDDDETEEDNNQDEYDPME---AEEAEEEEDDR-EEEEV----N
KRDDKRDV----------------------SRYCKDRPSKDKEKEKPQMVTVNRDLLMAF
VYF---DQSH------------------------CGYLLE---KDLEEILYT------L-
----GLHL----SR---AQVKKLLNKVVLRESC---------------------FYRKLT
DTSK--DGES----HDEP--ESLQGDT--------------------------TLGNRLL
LP--------TP-TVKQESKDGEEN-V-------------GLIVYNGA-------MVDVG
SLLQKLEKSEK--VR---------AEVEQKLQLLEEKTDEDGKTI-------LNLENS--
-N-------KSLSGELREVKKDLGQL----------QEN-------LKVSE------NMN
LQFENQLNKT----L-------R-------------NLSTVMD----------DIHTV--
---------LK-------------------------------------------------
-----KDNVKNEDRDQKSKE---------------------NGSSV--------------
------------------------------------------------
>gi|126272572|ref|XP_001362350.	Monodelphis domestica
-----------MAQFGGQKN-PPWA-TQFTATAVS---------------QPAAL---GV
QQPSLLGASPT-------IYTQQTALAAAGLTTPTP-A---NYQLTQTAALQQQ------
--AAAAAAALQQQYSQPQQALYSVQQQLQ---------QP-----QQTLLTQPAVALPT-
--------------SLSLS--------TPQPAAQITVS----------------------
YP-----TPRSSQQQPQTQ--------KQRVFTGVVTKLHDTF---------GFV-----
----------------DEDVFF----------QLSA-VKGK-------------------
-----TPQVGDRVL----VEAT---Y-NPSMPFKWNAQRIQTL------PNQNQSQTQPL
LKTPPAV-----------------L-QPLTQPTAFGV-QAQPQPQ--SLLQAQISAASIT
P---------L---------------------------LQTQPQPLLQQP----------
-----QQKAGLLQP-----------------------PV-------RIVSQPQPARR---
------------------------LDP------PSRFSGRND-RGDPVPNR---------
-------KDDRSRE-------------RE--RERRRSRE-RSPQRKRSRERSPR-----R
ERE----------------RSPRRPRR--VVPR--------YTVQFSKFSLDCPSCDMME
LRRRYQNLY-------------------------IPSDFFDAQFM-----WVDAFPLSRP
FQLGNYCNFYVM---HR-----------------EVDPLEKNVAILDP--PDADHLYSAK
VMLMASPSMED--LYHKSCALAEDPQ--E-LRDG----FQHPARLVKFLVGMKGKDEAMA
IGGHWSPSLDGP--DPEKDPSVL-IKTAI------------RCCKALTGIDL---SVCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WETLSR---GYK
--------------QQL---AEKL-----------------QGERKEADGEQDEE-----
-----------EKDDG---EAKEISTPTH-----WSKLDPKTM-KVND------------
--------------------LRKELESRALSSKGLKSQLIARLTKQLKV-EEQKEEQKEL
-------EKSEKE-----------------EEEEEDRKSEDDKE-----EEERKRQEEME
RQRRERR---Y-ILPDEPAI---------IVHPNWAAKSGKFDCSIMSLSVLL---DYRL
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYKSLISLPEKEDK-----KEKDKKS-
-------KKEERKEKREDRDDEMDDPKPKRRK-----SGDDKDRK-----DDREDRKKED
KRKD----------D-KDDDETEEDNNQEEYDPLE---AEDAEDEEDER-DEEEM----N
KRDDKREM----------------------NRYGKERTSKDKEKDKTQMVTVNRDLLMAF
VYF---DQSH------------------------CGYLLE---KDMEEILYT------L-
----GLHL----SR---AQVKKLLNKVVLRESC---------------------FYRKLT
DTSK--DDEN----HEDS--EALQEEM---------------------------LGNRLL
LP--------TP-TIKQESKVVEEN-V-------------GLIVYNGA-------MVDVG
SLLQKLEKSEK--VR---------AEIEQKLQLLEDKTGEDEKTI-------LHLENS--
-N-------KSLTCELREVKRDLGQL----------QEN-------LKTSE------NAN
LQFENQLNKT----I-------K-------------NLSTVME----------EIHIV--
---------LK-------------------------------------------------
-----KDNMKNDDRDQKSKE---------------------NGANV--------------
------------------------------------------------
>gi|119574314|gb|EAW53929.1|	Homo sapiens
MIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAA---------------QDDEMFQETV
EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTD---QASMPDNTAAQKVCHLMGI
NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT
HRQGASFLGILDIAGFEIF--------EVNSFEQLCIN----------------------
YT-----NEKLQQLFNHTM----FILEQEEYQREGIEWNFIDF---------GLDLQPCI
ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCT-EQGS-------------------
-----HPKFQKPKQLKDKTEFSIIHY-AGKVDYN-ASAWLTKN------MDPLNDNVTSL
LNASSDK-----------------F-VADLWKDVDRI-VGLDQMA--KMTESSLPSASKT
KKGMFRTVGQL---------------------------YKEQLGKLMTTLRNTTPNFVRC
IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPN-------RIVFQEFRQRYEIL
AANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIM
AFQAMC-RGYLARK-------------AFAKRQQQLTAM-KVIQRNCAAYLKLR-----N
WQWWRLFTKVKPLLQVTRQEEEMQAKE--------------DELQKTKERQQKAENELKE
LEQKHSQLT-------------------------EEKNLLQEQLQAETELYAEAEEMRVR
LAAKKQELEEIL---HE-----------------MEARLEEEEDRGQQ------------
----LQAERKK--MAQQMLDLEEQLE--EEEAAR----QKLQLEKVTAEAKIKKLEDEIL
VMDDQNNKLSKE--RKLLEERISDLTTNLAEEE--------EKAKNLTKLK----NKHES
MISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE--QIADLQAQIA-ELKMQL---AKK
--------------EEE---LQAA-----------------LARLDDEIAQKNNA-LKKI
--RELEGHISDLQEDL----DSERAARNK-----AEKQKRDLGEELEA------------
--------------------LKTELED-TLDSTATQQELRAKREQEVTVLKKALDEETRS
------HEAQVQE-----------------MRQKHAQAVEELTE---QLEQFKRAKANLD
KNKQTLE-KENADLAGELRVLG-------QAKQEVEHKKKKLEAQVQELQSKCSDGERAR
A---ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL
NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK-----KKLQDFASTV
EALE----------EGKKRFQKEIENLTQQYEEKA---AAYDKLEKTKNRLQQELDDLVV
DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE
ALEAKEELER------------------------TNKMLK---AEMEDLVSS------KD
DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ
ARDEQNEEKRRQLQRQLHEYETELEDE---------------------------RKQRAL
AA--------AA-KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-------MKDFQ
RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE--
-LASSLSGRNALQDEKRRLEARIAQL----------EEE-------LEEEQGNMEAMSDR
VRKATQQAEQ----L-------S-NELATERSTAQKNESARQQLERQNKELRSKLHEM--
---------EGAVKSKFKSTIAALEAKIAQLEEQVEQE----------------------
AREKQAATKSLKQKDKKLKE-ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE
SQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQETSQ--
>gi|33563288|ref|NP_080477.1|	Mus musculus
-----------MAQFGGQKN-PPWA-TQFTATAVS---------------QPAAL---GV
QQPSLLGASPT-------IYTQQTALAAAGLTTQTP-A---NYQLTQTAALQQQ------
-----AAAVLQQQYSQPQQALYSVQQQLQ---------QP-----QQTILTQPAVALPT-
--------------SLSLS--------TPQPAAQITVS----------------------
YP-----TPRSSQQQTQPQ--------KQRVFTGVVTKLHDTF---------GFV-----
----------------DEDVFF----------QLGA-VKGK-------------------
-----TPQVGDRVL----VEAT---Y-NPNMPFKWNAQRIQTL------PNQNQSQTQPL
LKTPTAV-----------------I-QPIVPQTTFGV-QAQPQPQ--SLLQAQISAASIT
P---------L---------------------------LQTQPQPLLQQP----------
-----QQKAGLLQP-----------------------PV-------RIVSQPQPARR---
------------------------LDP------PSRFSGRND-RGDQVPNR---------
-------KDDRSRE-------------RD--RERRRSRE-RSPQRKRSRERSPR-----R
ERE----------------RSPRRVRR--VVPR--------YTVQFSKFSLDCPSCDMME
LRRRYQNLY-------------------------IPSDFFDAQFT-----WVDAFPLSRP
FQLGNYCNFYVM---HR-----------------EVESLEKNMAVLDP--PDADHLYSAK
VMLMASPSMED--LYHKSCALAEDPQ--D-LRDG----FQHPARLVKFLVGMKGKDEAMA
IGGHWSPSLDGP--NPEKDPSVL-IKTAI------------RCCKALTGIDL---SVCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WETLSR---GYK
--------------QQL---VEKL-----------------QGERKKADGEQDEE-----
-----------EKDDG---EVKEIATPTH-----WSKLDPKAM-KVND------------
--------------------LRKELESRALSSKGLKSQLIARLTKQLKI-EEQKEEQKEL
-------EKSEKE-----------------EEDEDDKKSEDDKE-----EEERKRQEEVE
RQRQERR---Y-ILPDEPAI---------IVHPNWAAKSGKFDCSIMSLSVLL---DYRL
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYKSLLSLPEKEDK-----KDKEKKS-
-------KKEERKDKKEEREDDIDEPKPKRRK-----SGDDKDKK-----EDRDERKKEE
KRKD----------DSKDDDETEEDNNQDEYDPME---AEEAEDEDDDR-EEEE-----V
KRDDKRDV----------------------SRYCKDRPAKDKEKEKPQMVTVNRDLLMAF
VYF---DQSH------------------------CGYLLE---KDLEEILYT------L-
----GLHL----SR---AQVKKLLNKVVLRESC---------------------FYRKLT
DTSK--DDEN----HEES--EALQEDM---------------------------LGNRLL
LP--------TP-TIKQESKDGEEN-V-------------GLIVYNGA-------MVDVG
SLLQKLEKSEK--VR---------AEVEQKLQLLEEKTDEDGKTI-------LNLENS--
-N-------KSLSGELREVKKDLGQL----------QEN-------LEVSE------NMN
LQFENQLNKT----L-------R-------------NLSTVMD----------DIHTV--
---------LK-------------------------------------------------
-----KDNVKSEDRDEKSKE---------------------NGSGV--------------
------------------------------------------------
>gi|149625507|ref|XP_001520554.	Ornithorhynchus anatinus
------------------MDIGP------------------------------AL---GV
QQPSLLGASPT-------IYTQQTALAAAGLTTQTP-A---NYQLTQTAALQQQ------
--AAAAAAALQQQYSQPQQTLYSVQQQLQ---------QP-----QQTLLTQPAVALPT-
--------------SLSLS--------TPQPAAQITVS----------------------
YP-----TPRSSQQQTQPQ--------KQRVFTGVVTKLHDTF---------GFV-----
----------------DEDVFF----------QLSA-VKGK-------------------
-----TPQVGDRVL----VEAT---Y-NPNMPFKWNAQRIQTL------PNQNQSQTQPL
LKTPPAV-----------------L-QPITQPAAFSV-QAQPQPQ--SLLQAQISAASIT
P---------L---------------------------LQSQPQPLLQQP----------
-----QQKAGLLQP-----------------------PV-------RIVSQPQPARR---
------------------------LDP------PSRFSGRND-RGDTVPNR---------
-------KDDRSRE-------------RE--RERRRSRE-RSPQRKRSRERSPR-----R
ERE----------------RSPRRPRR--VVPR--------YTVQFSKFSLDCPSCDMME
LRRRYQNLY-------------------------IPSDFFDAQFM-----WVDAFPLSRP
FQLGNYCNFYVM---HR-----------------EVDPLEKNMAVLDP--PDADHLYSAK
VMLMASPSMED--LYHKSCALAEDPQ--E-LREG----FQHPARLVKFLVGMKGKDEAMA
IGGHWSPSLDGP--DPEKDPSVL-IKTAI------------RCCKALTGIDL---SVCTQ
WYRFAEIRYHRPEETHK-GRTVPAHVETVVLFFPD--VWHCLPTRSE-WETLSR---GYK
--------------QQL---VEKL-----------------QGERKEADGEQDEE-----
-----------EKDDG---EAKEISTPTH-----WSKLDPKTM-KVND------------
--------------------LRKELESRNLSSKGLKSQLIARLTKQLKV-EEQKEEQKEL
-------EKSEKE-----------------DDEEEDRKSEDDKE-----EEERKRQEEVE
RQRRERR---Y-VLPDEPAI---------IVHPNWAAKSGKFDCSIMSLSVLL---DYRL
E---DNKEHSFEVSLFAELFNEMLQRDFG--VRIYKSLVSLPEKEDK-----KEKDKKS-
-------KKEERKDKKEEREDETDEPKPKRRK-----SGDDKDKK-----EDREEKKKEE
KRKE----------DSKEDDETEEDNNQEEYDPLE---AEDAEDEEEDR-DEEEM----N
KREDKREG----------------------NRYCKERSSKDKEKEKAQMITLNRDLLMAF
VYF---DQSH------------------------CGYLLE---KDMEEILYT------L-
----GLHL----SR---AQVKKLLNKVVLRESC---------------------FYRKLT
DTSK--DEEN----HDES--ETLQEDM---------------------------LGNRLL
LP--------TP-TVKQECKTMEEN-V-------------GLIVYNGA-------MVDVG
SLLQKLEKSEK--VR---------AEIEQKLQLLEEKTNEDEKTI-------VHLENS--
-N-------KSLSGELREVKKDLSQL----------QEK-------LKTSE------DTN
LRFESQLNKT----I-------K-------------NLSTVMD----------EMHTV--
---------LL-------------------------------------------------
-----KDKVKHEDKDQNSKE---------------------NGANV--------------
------------------------------------------------
