>gi_187951843_gb_AAI38046.1_	Mus
--------------------
--------------------
--------------------
---------MLETIDKNRAL
QAAERLQSKLKERGDVANED
KLSLLKSVL-----------
--------------------
--------------------
---QSPLFSQILNLQTS---
LQQLKDQV-NIATLATAAAD
HAHTPQFSSAVISNLQSESL
LLSPNHGNLEALPGPGAPAV
MDGKPTCDELDQLIKNMAQG
R--------------HVEIF
ELL-----KPPCGGLGFSVV
GLRSENRGELGIFVQEIQEG
SVAHRDGRLKETDQILAING
QVLDQTITHQQAISILQKAK
DTVQLVIARGSLPPVSSPRI
SRSPSAASTISAH-SNPMHW
QHVETIELVNDGSGLGFGII
GGKATGVIVKTILPGGVADQ
HGRLCSGDHILKIGDTDLA-
----GMSSEQVAQVLRQCGN
RVKLMIARGAV--EETPASS
SLGI----TLSSSTSSTSEM
RVDASTQKNDESETFDVEL-
----TKNVQGLGITIAGYIG
D--------KKLEPSGIFVK
SITKSSAVEHDGRIQI--GD
QIIAVDGTNLQGFTNQQAVE
VLRHT--GQTVRLTLMRKGA
SQEAELTSRGDTAK-----D
VDLPA-------ENCEKDEE
SLSLKRN--TSILPIEEEGF
PLLSAELEEAE------DVQ
QEAALLTKWQRIMGINYEIV
VAHVSKFSENSG--------
-------LGISLEATV----
----GHHFIRSVLPEGPVGH
SGKLFSGD--ELLEV-----
----------NGINLLGENH
QDVVNILKELPI--DVTMVC
CRRTVPPIALSEMDSLDIND
LELTEKPHIDLGEF------
--------------------
---------IGSSETEDPML
AMSDVDQNAEEIQTPLAMWE
AGGQSIELEKGSRGLGFSIL
DYQDPIDP----ANTVIVIR
SLVPGGIAEKDGRLFPGDRL
MFVNDINLENSTL-EEAVEA
LKGAPS------GMVRIGVA
KPLP----LSPEEGYVSAKE
DAFLCSPHACKESGLS----
---DKALFRADLALIDTPDA
ESIAESRFESQFSPDNDSVY
STQASIFSLHDGTCSDGMNY
GP--SLPSSPPK--DVTSSS
EVVLGLHLSLEELYTQNLLQ
RQHAGSPPTDMRPAPTSGFP
IS--DYTTTNAVEQKYECAN
PVAWPHSQLPSS--LSTSEL
APALP---AVAQKYLTDQSS
LASDAE----SVNLQSMSQE
AFE--RTVTIAKGSSSLGMT
VSANKDGLGVIVRSIIHGGA
ISRDGRIAVGDCILSINEES
TISLTNAQARAMLRRHSL-I
GPDIKFSAAPADDRAPFYVI
TYVPAEHLEEFRVSFGQQAG
GIMALDIFSSYTGRDIPELP
EREEGEGEESELQNAAYSSW
SQPRRVELWREPSKSLGISI
VGGRGMGSRLSNGEVMRGIF
IKHVLEDSPAGKNGTLKPGD
RIIEVDGMDLRDASHEQAVE
AIRKAGNPVVFMVQSIINRP
RKSPLPSLPHSLYPKYSFSS
TNPFADSLQLTTDQAPSQSE
SETEKPALCNVPPSS---PS
VFSEMGSDCAQPSATAV---
SEDEDKEDEFGYSWKNIQER
YGSLTGQLHVIELEKGQSGL
GLSLAGNKDRTRMSVFIVGI
DPTGAAGRDGRLQIADELLE
INGQILYGRSHQN---ASSI
IKCAPSKVKIIFIR---NAD
AVNQMAVCPGIAADSPSSTS
DSPQNKEVEPCSTTSASAAD
LSSLTDVYQLELPKDQGGLG
IAICEEDTINGVMIESLTEH
GGAAKDGRLKPGDHILAVDD
EVVAGCPVEKFISLLKTAKA
TVKLTVRAENPACPAVPSSA
VTVSGERKDNSQTPAVP---
APDLEPIPSTSRSSTPAVFA
SDPATCPIIPGCETTIEISK
GQTGLGLSIVGGSDTLLGAI
IIHEVYEEGAACKDGRLWAG
DQILEVNGIDLRKATHDEAI
NVLRQTPQRVRLTLYRDEAP
YKEEDVCDTFTIELQKRPGK
GLGLSIVGKRNDTGVFVSDI
VKGGIADADGRLMQGDQILM
VNGEDVRHATQEAVAALLKC
SLGAVTLEVGRVKAAPFHSE
RRPSQSSQVSE-SSLSSFTP
PLSGINTSESLESNSKKNAL
ASEIQ------GLRTVEIKK
GPADSLGLSIAGGVG-SPLG
DVPIFIAMMHPNGVAAQTQK
LRVGDRIVTICGTSTDGMTH
TQAVNLMKNASGSI--EVQV
VAGGDVSVVTGHQQELANPC
LAFTGLTSSSIFPDDLGPPQ
SKTITLDRGPDGLGFSIVGG
YGSPHGDLPIYVKTVFAKGA
AAEDGRLKRGDQIIAVNGQS
LEGVTHEEAVAILKRTKGTV
TLMVLS
>gi_73971638_ref_XP_531935.2_	Canis
--------------------
-----MGGGGSEEISQNPIS
SPAQNLDAPQMARQITTLKL
AAGGTADMEAESGENKNRAL
QAAERLQAKLRERGDVANED
KLNLLKSVL-----------
--------------------
--------------------
---QSSLFSQILNLQTS---
VQRLKDQV-NTTTSVISNVE
YAHIPHTSPAVIPTLQNE-L
FLSSNNGNLEAFTGSGTLHI
-NGKPACDEFDQLIKNMAQG
R--------------HVEVF
ELL-----KPPCGGLGFSVV
GLRSENRGELGIFVQEIQEG
SVAHRDGRLKETDQILAING
QALDQTITHQQAISILQKAK
DNVQLVIARGSLPQLISPIV
SRSPSAASTISAH-SNPIHW
QHVETIELVNDGSGLGFGIV
GGKATGVIVKTILPGGVADQ
HGRLCSGDHILKIGDTDLA-
----GMSSEQVAQVLRQCGN
RVKLMIARGAI--EEPAAPN
SLGI----TLSSSPSSIPEM
QVDASTQKSEESETFDVEL-
----TKNVQGLGITIAGYIG
D--------KKLEPSGIFVK
SITKSSAVEHDGRIQI--GD
QIIAVDGTNLQGFTNQQAVE
VLRHT--GPTVHLTLMRRGV
KQEAELTSREDVTK-----D
MVLSPLNASGNKENYEKDED
SSSLSRN--TSILPIEEEGY
PLLSAEIEDIE-----DAQQ
QEAALLTRWQRIMGINYEIV
VAHVSKFSENSG--------
-------LGISLEATV----
----GHHFIRSVLPEGPVGH
SGKLFSGD--ELLEV-----
----------NGITLLGENH
QDVVNILKELPI--EVTMVC
CRRTVPPTSQSGLDSLDLCD
IELTEKPHVDLGEF------
--------------------
---------IGSSETEDPVL
AMTDVSQNAEEVQGPLAMWE
VDVQHIELEKGNKGLGFSIL
DYQDPIDP----TSTVIVIR
SLVPGGIAEKDGRLLPGDRL
MFVNDVNLENSSL-EEAVQA
LKGAPS------GTVRIGVA
KPLP----LSPEEGYVSAKE
DSFLHPRHSCEEEGPA----
---DRALFRADLALVDTNEA
DLADESTFESQYSPDNDSIY
STQASILSLHGSACSDGLNY
GP--SLPSSPPK-DVTENSS
DPVLDLHMSLEELYTQNLLQ
RQDESPSSVDLSMAPASGFT
VN--DYTPANAIEQQYKCEN
TRTWAESHLPNEIISSAELT
SPVLPDSTGKGSEFLIQQSS
LTSTGE----CVMLQNLSKE
MFE--RTITIAKGNSSLGMT
VSANKDGLGMIVRSIIHGGS
ISRDGRIAVGDCILSINEES
TISLTNAQARAMLRRHSL-I
GPDIK--------------I
TYVPAEHLEEFKISLGQQPG
GVMALDVLSSYTGRDIPELP
EREEGEGEESELQNAAYSNW
NQPRRVELWREPSKSLGISI
VGGRGMGSRLSNGEVMRGIF
IKHVLDDSPAGKNGTLKPGD
RIVEVDGMDLRDASHEQAVE
AIRKAGNPVVFMVQSIINRP
RKSPLPSLPHNLYPKYNFSS
TNPFADSLQFNADKAPSQSE
SEPEKAPLSTVPPPP---SS
AFAEMSSDHTQSSASKI---
SEDVDKEDEFGYSWKNVRER
YGTLTGELHMIELEKGRSGL
GLSLAGNKDRSRMSVFVVGI
DPNGAAGKDGRLQIADELLE
INGQILYGRSHQN---ASSI
IKCAPSKVKIIFIR---NKD
AVSQMAVCPGNTVEPLPSAS
ENSQNKEAEPTGTTSDAAVD
LCSFKNVQHLELPKDQGGLG
IAITEEDTLSGVVIKSLTEH
GVAAKDGRLKVGDQILAVDD
EVVVGYPVEKFISLLKTAKT
TVKLSIRAENRDPQAVASAA
GAASGEQKSSSLALMAPSSG
SPEPESIPSTSRSSTPAIFA
SDPATCPIIPGCETTIEISK
GRTGLGLSIVGGSDTLLGAI
IIHEVYEEGAACKDGRLWAG
DQILEVNGIDLRKATHDEAI
NVLRQTPQRVRLTLYRDEAP
YKEEDVYDTLTIELQKKPGK
GLGLSIVGKRNDTGVFVSDI
VKGGIADADGRLVQGDQILT
VNGEDVRNATQEAVAALLKC
SLGTVTLEVGRIKAGPFHSE
RRPSQSSQMSE-GSLSSFTF
PLSGSSTSESLESSLKKNAL
ASEIQ------GLRTVEIKK
GPADSLGISIAGGVG-SPLG
DVPIFIAMMHPNGVAAQTQK
LRVGDRIVTICGTSTEGMTH
TQAVNLLKNAPGSI--EMQV
VAGGDVSVVTGHQQEPASSS
LSFTALTSSSIFQDDLGPPQ
CKSITLDRGPDGLGFSIVGG
YGSPHGDLPIYVKTVFAKGA
ASEDGRLKRGDQIIAVNGQS
LEGVTHEEAVAILKRTKGTV
TLMVLS
>gi_187954613_gb_AAI40794.1_	Homo
--------------------
--------------------
--------------------
---------MLEAIDKNRAL
HAAERLQTKLRERGDVANED
KLSLLKSVL-----------
--------------------
--------------------
---QSPLFSQILSLQTS---
VQQLKDQV-NIATSATSNIE
YAHVPHLSPAVIPTLQNESF
LLSPNNGNLEALTGPGIPHI
-NGKPACDEFDQLIKNMAQG
R--------------HVEVF
ELL-----KPPSGGLGFSVV
GLRSENRGELGIFVQEIQEG
SVAHRDGRLKETDQILAING
QALDQTITHQQAISILQKAK
DTVQLVIARGSLPQLVSPIV
SRSPSAASTISAH-SNPVHW
QHMETIELVNDGSGLGFGII
GGKATGVIVKTILPGGVADQ
HGRLCSGDHILKIGDTDLA-
----GMSSEQVAQVLRQCGN
RVKLMIARGAI--EERTAPT
ALGI----TLSSSPTSTPEL
RVDASTQKGEESETFDVEL-
----TKNVQGLGITIAGYIG
D--------KKLEPSGIFVK
SITKSSAVEHDGRIQI--GD
QIIAVDGTNLQGFTNQQAVE
VLRHT--GQTVLLTLMRRGM
KQEAELMSREDVTK-----D
ADLSPVNASIIKENYEKDED
FLSSTRN--TNILPTEEEGY
PLLSAEIEEIE-----DAQK
QEAALLTKWQRIMGINYEIV
VAHVSKFSENSG--------
-------LGISLEATV----
----GHHFIRSVLPEGPVGH
SGKLFSGD--ELLEV-----
----------NGITLLGENH
QDVVNILKELPI--EVTMVC
CRRTVPPTTQSELDSLDLCD
IELTEKPHVDLGEF------
--------------------
---------IGSSETEDPVL
AMTDAGQSTEEVQAPLAMWE
AGIQHIELEKGSKGLGFSIL
DYQDPIDP----ASTVIIIR
SLVPGGIAEKDGRLLPGDRL
MFVNDVNLENSSL-EEAVEA
LKGAPS------GTVRIGVA
KPLP----LSPEEGYVSAKE
DSFLYPPHSCEEAGLA----
---DKPLFRADLALVGTNDA
DLVDESTFESPYSPENDSIY
STQASILSLHGSSCGDGLNY
GS--SLPSSPPK-DVIENSC
DPVLDLHMSLEELYTQNLLQ
RQDENTPSVDISMGPASGFT
IN--DYTPANAIEQQYECEN
TIVWTESHLPSEV-ISSAEL
PSVLPDSAGKGSEYLLEQSS
LACNAE----CVMLQNVSKE
SFE--RTINIAKGNSSLGMT
VSANKDGLGMIVRSIIHGGA
ISRDGRIAIGDCILSINEES
TISVTNAQARAMLRRHSL-I
GPDIK--------------I
TYVPAEHLEEFKISLGQQSG
RVMALDIFSSYTGRDIPELP
EREEGEGEESELQNTAYSNW
NQPRRVELWREPSKSLGISI
VGGRGMGSRLSNGEVMRGIF
IKHVLEDSPAGKNGTLKPGD
RIVEVDGMDLRDASHEQAVE
AIRKAGNPVVFMVQSIINRP
R-------------------
--------------APSQSE
SEPEKAPLCSVPPPP---PS
AFAEMGSDHTQSSASKI---
SQDVDKEDEFGYSWKNIRER
YGTLTGELHMIELEKGHSGL
GLSLAGNKDRSRMSVFIVGI
DPNGAAGKDGRLQIADELLE
INGQILYGRSHQN---ASSI
IKCAPSKVKIIFIR---NKD
AVNQMAVCPGNAVEPLPSNS
ENLQNKETEPTVTTSDAAVD
LSSFKNVQHLELPKDQGGLG
IAISEEDTLSGVIIKSLTEH
GVAATDGRLKVGDQILAVDD
EIVVGYPIEKFISLLKTAKM
TVKLTIHAENPDSQAVPSAA
GAASGEKKNSSQSLMVPQSG
SPEPESIRNTSRSSTPAIFA
SDPATCPIIPGCETTIEISK
GRTGLGLSIVGGSDTLLGAI
IIHEVYEEGAACKDGRLWAG
DQILEVNGIDLRKATHDEAI
NVLRQTPQRVRLTLYRDEAP
YKEEEVCDTLTIELQKKPGK
GLGLSIVGKRNDTGVFVSDI
VKGGIADADGRLMQGDQILM
VNGEDVRNATQEAVAALLKC
SLGTVTLEVGRIKAGPFHSE
RRPSQSSQVSE-GSLSSFTF
PLSGSSTSESLESSSKKNAL
ASEIQ------GLRTVEMKK
GPTDSLGISIAGGVG-SPLG
DVPIFIAMMHPTGVAAQTQK
LRVGDRIVTICGTSTEGMTH
TQAVNLLKNASGSI--EMQV
VAGGDVSVVTGHQQEPASSS
LSFTGLTSSSIFQDDLGPPQ
CKSITLERGPDGLGFSIVGG
YGSPHGDLPIYVKTVFAKGA
ASEDGRLKRGDQIIAVNGQS
LEGVTHEEAVAILKRTKGTV
TLMVLS
>gi_187608647_ref_NP_001120657.1_	Danio
--------------------
--------------------
--------------------
---MYENVPTVSASERQQVL
QALERLQSKLVQREEWTHSD
RLGTLKEAL-----------
--------------------
--------------------
---QSPLFSHILTLQHS---
VKQLKDQLNSLPPDTCSEFS
FSRKGQL-------IVSASR
PSSSLGSVLSNGTALT----
---NASSEQLQRWIQAAAKG
R--------------KTELI
SLQ-----KPLSGGLGFSVV
GLRPEGVGGHGVFVRQVQPG
SVADRDGRLLENDQILAING
IPLDQSVTQQQAIALLQQQK
DRVELVVAR-------DTAL
KPRLSASAPITTD-----QW
GHVEEIELVNDGSGLGFGIV
GGKTTGMVVRTVVPGSVADK
DGRLRTGDHILRIGDTMTR-
----GLASDQVVQVLQACGA
HVRMLIAREPLGAKQPAPPP
APAMGPVSSLPPPPPVPA--
RRASRTPNLEGFEIHEVAL-
----KKEGQSLGISIIGHNA
L--------TSEDAVGVYVK
NVIPGSIAEQTGKIQI--HD
RIISLDGVNLQGYNNQEVLE
VMKQS--GDVVHLTLVRKII
SPKRTTMEKSLDKV------
----------QRESSRVSLK
RSSEMKARADQRGSVVESID
PALSGIKQQLQANMQEPASL
TEMELRAKWEQALGPHYDVM
IVQLDPVIEDDIELQKYSKL
LPIHTMRLGVELDSFD----
----GHHYISTVAPEGPVAK
HGLLRPED--ELLEV-----
----------NGVQLYGKSR
RESVAFLREVPT--PFTLVC
CRRLAKEDNEYHPESEDWHS
SSLQEQIEHNLSMLARDTSL
RDSIREEFQARQASAVEREV
DDEGEPLEPISPEKEQMDQE
NDDDDEEEEEEDEGELALWS
PNVQVLELEKAERGLGFSIL
DYQDPMDV----ARSVIVIR
SLVPGGVADNHGGIFPGDQL
VFVNDTHLETCSL-AQAVEV
LKSAPP------GKVYLGIR
KPLAAEDRGSGQQSLWPVES
VDEQPTAKQAVSHTLPPMPE
DFVNGSI--LSDDLDEEPEL
ILDAEPRYASPLT-------
--------------------
----TVDLQPDV--------
---------------EKEMA
VDEEEEDVDVNVMEDQQSSK
VN-------DTSLPSYLSEK
SRSWEEPATSSR--YHLNTE
PDLQE---------------
--QVDDDLSMNLEKIQLQPL
KIPLGHFTSWVETAD-----
--------------------
---------------SD---
--SDSRNEGSEL----TL-T
DTDNE--------------S
AQRTSSRNKKRRNQAGPTRG
DL-----------------P
EREEGEGEET----PVFSHW
GPPRRVEVWAEPEESLGISI
VGGRTVIKRLKNGEELKGIF
IKQVLADSPAGRTGALKTGD
KILQVSGVDLQNASHEEAVQ
TIKAAPSPVVFIVQSLSSTP
RPV-----------------
---SVTASSIKQHKAKRKAA
QKAGQ----GAAPPPMRLP-
----------PPYRPPSQVQ
EEEHEQEEEDEQDTEVIRQR
YADLPGELLIVELEKDRNGL
GLSLAGNRDRSCMSIFVVGI
TTGGPASRDGRIKVGDELLE
INSQVLYGRSHQN---ASAI
IKSAASKVKLVLVR---NED
AINQMAVTPFPSQPALFSSS
ETHENPPAVPAEKPQLPE--
----------SLPLSRSPPE
NTLNKDQACVTATASSDPTH
KSLTD---------------
----------GESAVKKLKP
AEKLLESPSEQSAKPQVEQI
PSLPKLQRSSTKPSAGSLEV
TSSASSVPVSGTSPDFEYCS
KDPATCPIVPGQETVIEISK
GRSGLGLSIVGGKDTQLDAI
VIHEVYEEGAAARDGRLWAG
DQILEVNGVDLRSVAHEDAI
AALRQTPPKVRLTVLRDEAQ
YRDEENLDVFPVELQKKTGR
GLGLSIVGKRNGKGVFISDV
VKGGAADLDGRLMQGDQILS
VDGEDMRQASQETVAAILK-
--------------------
--------------------
--------------------
--------------------
GPTDALGISIAGGKG-SPLG
DIPIFIAMIQANGVAAKTHR
LKVGDRIVSINSQSLDGLTH
ADVVNMLKNAYGAI--ILQV
VADTNISAIA---SQVESLS
SSSAPSTNPEVRLVEPETPK
PKSITLEKGSEGLGFSIVGG
FGSPHGDLPIYVKTVFGKGA
AAVDGRLKRGDQLLSVNGES
LEGVTHEQAVAILKKQRGSV
TLSVLT
>gi_119850869_gb_AAI27286.1_	Xenopus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------------FSVV
ALKNPTVGEAGVFIREVQPG
SIADKDGRLKENDQILAINY
IPLDMSVSHQESIAMLQQSS
GSIRLVVAK-------APVL
NNFQALSNNLDNQ----IQW
GHVEDIELINDGSGLGFGIV
GGKASGVIVRTIVSGGLADR
DGRLKTGDHILQIGDTNVQ-
----GMASDQVAQVLRNCGN
SVKMVVARDPI--ERPSKPP
APA-----TLPVG--ALP--
PKDVKGDNENTDNVYDIKLT
----KKEGQSLGITVVGYTG
A--------FNGGSSGIYVK
SIIPGSAADQSGCIQV--QD
RIIAVDGVNIQDYSNQDVVA
ALRNT--GQTVHLTLSRSKE
LLELVATERSLVRV------
----------------PGLP
SDPPVPE--INKSSANEENQ
EQVDNYKNEMI---TGSLSP
QTSILKSKWEQRLGPDYLVM
VVNLDPKIDDDAELQKYSKL
LPIHTMRLGVELDSFD----
----GHHYISSIAPEGPVAK
LGIFQPED--ELLEV-----
----------NGVQLYGKSR
REAVSFLKEVPP--PFTLVC
CRRMVDDENETFVDVPNTLD
TKD-NKNEIPVTEEEDQT--
--------------------
---------VQSSERSNSEY
AQPLENLVTEEDDGELAMWS
SEVKVVELEKDSGGLGFSIL
DYQDPLDP----ARTVLVIQ
SLVSNGVAETSGQILPGDRL
VFVNDNYMDNASL-EDAVQI
LTSVPP------GRTRLGIC
KPLV----GSIKEEKDIYTN
LEELEDNTDSTAKDSV----
--ILDVFHKYKEGVFIQDE-
--------QEELVDEPS---
-----------------LNM
GK--QFNIEHNKTGSLQESW
EMQE-----LEGYGGEREML
VDEEYTEQENFSEDSDHYFL
QC--EGIAMPPGKDSGYSQP
---WMEDIHMDS--GAMKFK
LETQE--------------T
MLCHQDDLQTGVSQGTVYSL
-----KEPGIVFD-------
--------------------
---------------PD---
--AIAQQKDREM-------M
EDYTR--------------I
IHQKTQRNQLGASN------
EL-----------------P
EREEGEGEET----PNFSHW
GPPRIVEIWKEPQVSLGISI
VGGQSIIKRLKNGEELKGIF
IKQVLENSPAGKTNALKTGD
KILEVSGVDLKNATHEEAVN
AIKNSGNPVVFIIQSLSPTP
R-------------------
LMTAGNTKTSKYDKASTDST
VKTVSPVPFSGGPPPMKLP-
----------PPYKESS---
DSHPLEMKAEEDSDDKIRQR
YADLLGDLHIIELEKDKNGL
GLSLAGNKDRSRMSIFVVAI
NPDGPAGQDGRIHVGDELLE
INNQIIYGKSHQN---ASAI
IKGAPSTLKLVFIR---NKD
AVQQMAVNPDPLPESSLTDE
E-------------------
---------------HCGLA
VSGKGEETSFKEIMASVTES
EAKPA---------------
----------IDNQQKHSKS
DTKISPDSQDVSLTSVPSY-
--------------------
LPAESDISNYRNMPSP-LPS
FDPATCPIIPGQEMTIEISK
GRSGLGLSIVGGNDTPLEAI
VIHEVYEEGAAARDGRLWAG
DQILEVNGVDLRNASHEDAI
TALRQTPQKVQLTVYRDEAQ
YKDEENLDIFHVELQKKAGR
GLGLSIVGKRTGSGVFISDI
VKGGAADIDGRLMQGDQIMS
VNGDDMRNASQEIVATVLKC
AQGLVHLEIGRLRVGSWLAS
KKTFEASQINQMSSHGVLPP
SLTPVISSMQDYASSKKSSA
DSSQRHSGTDLEPRTVEINR
GPYDALGISIAGGKG-SPLG
DIPVFIAMIQASGVAARTHK
LKVGDRLVSINQQPVDGLSH
AEVVNILKHAFGTI--VLQV
VADTNISAIA---SQLESMS
LGQGVSSEHQVEDGESPVPK
IIHLE--KGGDGLGFSIVGG
YGSPQGDLPIYVKTIFSKGA
AAADGRLKRGDQILSVNGES
LEGVTHDEAVAILKKQRGNV
TLSVLS
>gi_194211264_ref_XP_001501210.2_	Equus
--------------------
--------------------
--------------------
-------MPENPAADKLQVL
QVLDRLKMKLQEKGDASQNE
KLSVFYETL-----------
--------------------
--------------------
---KSPLFNQILTLQQS---
IKQLKGQLSHTPSDCSTNFD
FSRKGLL-------VLTDGA
ITNRNAHRPSSNLTVSGLFP
WTPKSGNEDFHSVIQQMAQG
R--------------QVEYI
DIE-----RPSAGGLGFSVV
AVRSHTLGEVDIFVKEVQPG
SIADRDQRLKENDQILAINH
TPLDQRVSHQQAIALLQQTT
GSLHLVVAR-------EPVH
TKSSASTSPPDTTLPETVRW
GHVEDVELINDGSGLGFGIV
GGRSSGVVVRTIVPGGLADR
DGRLQTGDHILKIGGTNVQ-
----GMTSEQVAQVLRNCGD
SVRMLVARDPVG-EVFVTPP
TPS-----ALPVALPALA--
NSAPSSDKSALFETYDVELI
----KEDGQSLGIRIIGYAG
TP-------NTGEASGIYVK
SVIPGSAAHHNGQIRV--ND
RIVAVDGVNIQGFANQDVVE
VLRNA--GQVVRLTLARRKT
SSSASPLELPSDRG-----A
VVEPP----KTPTLFLTGAV
ETETNLD--SEDEDTEERMD
NLKTNSVQALERLERVPDF-
PENELKSRWENLLGPDYEVM
VATLDTQIADDAELQKYSKL
LPIHTLRLGMEVDSFE----
----GHHYISSIAPGGPVDT
LNLLQPED--ELLEV-----
----------NGVRLYGKSR
REAVSFLKEAPP--PFVLVC
CRRLFDDE------------
----ASVDEPRAPV------
--------------------
---------ASPPETQADHS
VDVNPEE---DDDGELALWS
SEVKIVELVKDHRGLGFSIL
DYQDPLDP----TRSVIVIR
SLVVDGVADRGGELLPGDRL
VSVNEHSLDNSTL-AEAVEV
LKAVPP------GTVRLGIC
KPL---------------ED
DNEEESHYILQSNHHE--DR
TEISGTIHDINSSLILEAPK
GFRDEPHFKEELVDKPF---
-----------------LDL
GK--SFQSQQKEVDNSKEAW
EMHEFLTPRSQEMGEEREML
VDEEYELYQDGFQPTELYSP
SRVQEAARVPSVEELHLGAQ
---RLHGAREDG--EPAQPQ
EARAL--------------L
GVCPPEAQQWGCGPDDLMKE
DFGIDASPSVPSPEGSGQQG
RFGGLENLSSFPQSSSDLGM
MIPDDVQAPGLLVELPA---
--VAQRREQEDL----PLYQ
LPRTR--------------V
VSKASAYTGILSSRYATDTC
EL-----------------P
EREEGEGEET----PNFSHW
GPPRIVEIFREPNVSLGISI
VGGQTVIKRLKNGEELKGIF
IKQVLEDSPAGKTNALKTGD
KILEVSGVDLQNASHREAVE
AIQNAGNPVVFVVQSLSPTP
R-------------------
VIPSVHNKANKIANN-QDED
TQEKKEKRRGTAPPPMKLP-
----------PPYKAPS---
DDSDENEDGDVFTNKKIRQR
YADLPGELHIIELEKDKNGL
GLSLAGNKDRSRMSIFVVGI
NPEGPAATDGRMRIGDELVE
INNQILYGRSHQN---ASAI
IKTAPSKVKLVFIR---NED
AVNQMAVAPFPLPSSPPSSL
E-------------------
--------------VRAFIF
PFSSEEDSSLEVSVKPLPES
GSFFL---------------
----------AVSQMKQQQY
SAQVSLGSQDIPLAPAPSY-
--------------------
SSTDADFPGYGGFQAP--LS
VDPATCPIVPGQEMIIEISK
GRSGLGLSIVGGKDTPLDAI
VIHEVYEEGAAARDGRLWAG
DQILEVNGIDLRSASHEEAI
TALRQTPQKVRLVVYRDEAH
YRDEQNLEIFPVHLQKKAGR
GLGLSIVGKRSGNGVFISDI
VKGGAADLDGRLIQGDQILS
VNGEDMRNASQETVATVLKC
AQGLVQLEIGRLRAGSWTSL
RKTLQNSQGSQHSTHSSCHP
PLPPVVSSLQNLVGAKR-AS
DPSPQNPGMDVGPRTVEIIR
EPSDALGISIAGGRG-SPLG
DVPIFIAMIQASGVAARTQR
LKVGDRIVSINGQPLDGLSH
ADVVNLLKNAYGRI--ILQV
VADTNISAIA---TQLENMS
AGY-HLGSPSAEHHPDDTEE
QLQVTAD-------------
--------------------
--------------------
--------------------
------
>gi_73956197_ref_XP_852343.1_	Canis
--------------------
--------------------
--------------------
-------MPENPAPDKLQVL
QVLDRLKMKLQEKGDTSQNE
KLSLFYETL-----------
--------------------
--------------------
---QSPLFNQILTLQQS---
IKQLKGQLSHIPSDCSTNFD
FSRKGLL-------VFTDSA
ITNGNAQRPSNNLTVSGLFP
WTPKSGNEDFNSVIQQMAQG
R--------------QIEYI
DIE-----RPSTGGLGFSVV
ALRSQNLGEVDIFVKEVQPG
SIADRDQRLRENDQILAINH
TPLDQNISHQQAIALLQQTT
GSLHLVVAR-------EPVH
TKSRTSINLTDTTMPETVHW
GHIEDVELINDGSGLGFGIV
GGKSSGVVVRTIVPGGLADR
DGRLQTGDHILKIGDTDVQ-
----GMTSEQVAQVLRNCGN
SVRMLVARDPVG-ETSVTPP
TPA-----ALPVALPAVA--
NRSPSTD-SSLYETYGVELI
----KKDGQSLGIRIVGYIG
TA-------HTGEASGIYVK
SIIPGSAAYHNGQIQV--ND
KIVAVDGVNIQGFTNQDVVE
VLRNA--GQVVHLTLVRRKM
CSSTSPLERSSDRG-----T
VVEPS----GTPARYVTGAV
ETETNLD--GGDEETEERMD
NLKNDNIQALEKLERVPDS-
PENELKSRWENLLGPDYEVM
VATLDTQIADDAELQKYSKL
LPIHTLRLGMEVDSFD----
----GHHYISSIAPGGPVDA
LNLLQPED--ELLEV-----
----------NGVQLYGKSR
REAVSFLKEVPP--PFTLVC
CRRLFDDE------------
----ASVDEPRTTE------
--------------------
---------TLLPEMEADHN
VDINTEE---EEEEELALWS
PEVKIVELVKDHKGLGFSIL
DYQDPLDP----TRSVIVIR
SLVANGVAEKGGELLPGDRL
VSVNEYCLENTTL-AEAVEV
LKAVPP------GIVHLGVC
KPL---------------DN
DKEEESHYILHSNNNE--DE
TELSETIHDINSSLILEAPK
GFRDEPYYKEELVDEPF---
-----------------LDL
GK--AFQSQQKEIDNSKEAW
EMQEFLPPRLQEMGEEREML
VDEECDLYQDHFQSMDLYPS
SHLQEAAPVSSVKELHFGTQ
---WLHDSEPPE------LQ
EARSM--------------M
NMYSQETQQYGYSTENMIKE
NFGIDSLPSISSSEGNSQQG
RFDDLENLNSLTKSSLDLGM
MIPNDVQGPGMLVELPA---
--VAQRREQEDL----PLYQ
LPRTR--------------V
VSKASAYTGASSSRYTAGAC
EL-----------------P
EREEGEGEET----PNFSHW
GPPRIVEIFREPNVSLGISI
VGGQTVIKRLKNGEELKGIF
IKQVLEDSPAGKTNALKTGD
KILEVSGVDLQNASHREAVE
AIKNAGNPVVFVVQSLSSTP
R-------------------
VIPSVHNKANKIANN-QDQN
TEEKKEKRQGTPPPPMKLP-
----------PPYKAPS---
DDSDENEEEYAFTNKKIRQR
YADLPGELHIIELEKDKNGL
GLSLAGNKDRSRMSIFVVGI
NPEGPAATDGRMRIGDELLE
INNQILYGRSHQN---ASAV
IKTAPSKVKLVFIR---NED
AVNQMAVAPFPVPSSSPSSL
E-------------------
--------------DQSGTE
PVSSEEDGSLEVGIKQLPEN
ESSKL---------------
----------AVSQMKPQKY
STKVSFSSQEIPLAPAPSY-
--------------------
HSTDVDFTSYGGFQAP--LS
VDPATCPIVPGQEMIIEISK
GRSGLGLSIVGGRDTPLDAI
VIHEVYEEGAAARDGRLWAG
DQILEVNGIDLRSASHEEAI
TALRQTPQKVRLVVYRDEAH
YRDEENLEIFPVDLQKKAGR
GLGLSIVGKRNGSGVFISDI
VKGGAADLDRRLIQGDQILS
VNGEDMRNASQETVATVLKC
AQGLVQLEIGRLRAGSWTSS
RKTSQNSQGSQHSTHSSFHP
SLAPVITSLQNLVGTKR-AT
DPSLKSSGMDMGPRTVEIIR
ELSDALGISIAGGKG-SPLG
DIPIFIAMIQASGVAARTQK
LKVGDRIVSINGQPLDGLSH
ADVVNLLKNAYGRI--ILQV
VADTNISAIA---TQLENMS
TGY-HLGSPTAEHHPEDTE-
--------------------
--------------------
--------------------
--------------------
------
>NP_689739.4
--------------------
--------------------
--------------------
-------MKVTVCFGRTGIV
VPCKEGQLRVGELTQQALQR
YLKTREK-------------
--------------------
--------------------
---GPGYWVKIHHLEYTDGG
ILDPDDVLADVVEDKDK---
--------------------
--------------------
--------------------
---------------LIAVF
EEQ-----EPLHKIESPSG-
--NPADRQSPDAFETEVAA-
-------QLAAFKPI--GGE
IEVTPSALKLGTPLLVRRSS
DPV-----------------
-----PGPPADTQ---PSAS
H-------------------
---PGGQSLKLVVPDSTQNL
EDR------------EVLN-
----GVQTELLT-----S--
---------------PRTKD
TLS-----------------
---------DMTRTVEI---
----SGEGGPLGIHVVPFFS
S--------LSGRILGLFIR
GIEDNSRSKREGLFHE--NE
CIVKINNVDLVDKTFAQAQD
VFRQAMKSPSVLLHVLPPQN
REQYEKSVIGSLNIFGNNDG
VLKTK---VPPPVHGKSGLK
TANLT----GTDSPETDASA
SLQQNKSPRVPRLGGKPSSP
SLSPLM-----GFGSNKNAK
KIKIDLKKGPEG--------
-------LGFTVVTRDSSIH
--GPGPIFVKNILPKGAAIK
DGRLQSGD--RILEV-----
----------NGRDVTGRTQ
EELVAMLRSTKQGETASLVI
ARQ-----------------
----EGHFLPREL-------
--------------------
--------------------
--------------------
--------------------
--------------------
----------DGRLRMNDQL
IAVNGESLLGKSN-HEAMET
LRRSMSMEGNIRGMIQLVIL
RRP-----------------
ERPMEDPAECGAFSKP----
-------------CFENCQN
AVTTSRRNDNSIL-------
-----------------HPL
GT-----CSPQD--------
--------------KQKGLL
LPNDG---------------
--------------------
---WAESEVPPS--PTPHSA
LGLGL--------------E
DYSHSS----GVDSAVYFPD
QHI--NFRSVTPARQ-----
--------------------
---------------PE---
--SINLKASKSM----DL-V
PDESK--------------V
HSLAGQKSES----------
-------------------P
SKDFGP--------------
--------------TLGL--
-------KKSSSLESLQ---
-TAVAEVRKN-DLPFHRPRP
HMVRGRGC---NESFRAAID
--KSYDGPE-----------
--------------------
---EIEADGL------SDKS
SHSGQGALNCESAP------
---------------QG---
NSELEDMENKARKVKKTKEK
EK-----------KKEKGKL
KVKEKKRKEENEDP------
------ERKIKKKGFGAMLR
F------GKKKEDK--GGKA
EQKG--TLKHGGLR---EEE
LEK-----------------
--------------------
--------------------
--MKEERERIGAKHQELREK
QARGL---------------
-----------------LDY
ATGAIGSVYDMD--------
--------------------
--DDEMDPNYARVNHF-REP
CTSANVFRSPSPPRAGPFGY
PRDGHPLSPERDHLEGLYAK
V-NKPYHPLVPADSGR----
-----------PTGGSTDRI
QKLRKEYYQAR----REGFP
LYEDD---------------
-------EGRARPSEYDLLW
VPGRGPD-------------
GNAHNLRFEGMER-------
---------------QYASL
PRG-----------------
--------------------
--------------------
GPADPVDYLPAAPRGLYKER
ELPYYP--------------
----------GAHPMHPP--
-------KGSYPRP--TELR
VADLRYPQ-----HYPPPPA
PQH---KGPFRQDVPPSPPQ
HQRMPAYQET---------G
RPGPRGGSP-----------
--------------------
------DQYPYRTQDSRQKN
PMTAAV
>gi_47228131_emb_CAF97760.1_	Tetraodon
--------------------
--------------------
--------------------
-------MKVTVCFGRTRVV
VPCGDGNIQVHRLIQQAVMR
YKKAIAKELLFIIPVVPEVA
AGGGPKEAVREACLKFPTRG
HRKISIRIRQPGLLVSCLPF
PVEDSSYWLQVHRLEHSDGG
ILDLDDVLCDVADDKDRDSS
YWLQVHRLEHSDGGILDLDD
VLCDVADDKDRNSQTHSSES
RLRVGFRPRNNLDLSLVGQS
RLSSVHTHSSPSSAPLVAVY
EEQ-----EPHHGGDGTSA-
--SSTGTQSPDLFAADLSAG
------GGASAFQPYHAASE
IEVTPSALRSNMPLHVRRSS
DPALLTVNGPFGGGGGGGGE
ARVRTEEPPSRKN---PTRW
S-------------------
---TTAGFLKARHSSGTNSL
ERKGKSMDTYRSLPRDAGTW
ANHREFQRETARSSLSANHP
MVDRWLERQEQ--EEEVGRR
ENG-----RIDPVGRSDSCV
DHVPVRSLEDIVKLVEV---
----SNDGGPLGIHVVPFSG
---------RDRRTLGLLVK
RLERGGKAEQQGLFQE--ND
CIVRINHGDLRSVRFEQAQN
MFRQAMRSPVIMFHVVPSSM
KARYEQLSHAERNPAPYASG
RFSPD-------SLGGSSLS
AFDHAPSRMSRHGQEQPDTY
PPVSHPAVSAAKPPTGQTHS
PQRALTSTPTAGL-SKKVGR
RLSIQLKKGPEG--------
-------LGFSITSRDVPLG
--GSAPIYVKNILPRGAAIQ
DGRLKAGD--RLLEVR---T
RPSPVQQQQVSGVDLNGRTQ
EEVVSLLRATPMGGAVGLLV
LRQ-----------------
----EDPFLPREE-------
--------------------
--------------------
-KTEEEELVLTPDGSREFLT
LEIPLSD--SGSAGLGVSVK
GNRSRENH----ADLGIFVK
SIINGGAACKDGRLRINDQL
IAVNGESLLGKTN-QDAMET
LRKSMSTEGNKRGMIQLIVA
RRL---------------AK
RSEVRTPPIRAGSASPQRAD
ASLDDHERRISHSLYGGLD-
GLDDNLMPRQGLMP------
-----------------RTV
G---NYQLSPTV--------
-----------NMPQDDTVI
IEDDRPPLLPPHLSDQSSSS
SH--DDVAFAPAATPP----
---WAKEPPSQN--HDSGSL
DQSDP--------------D
PAFQRE----GFGRQSMSEK
-----RTKQFGDASQ-----
--------------------
---------------LE---
--IIKTRKSKSM----DL-V
ADEIN--------------L
SPRPNTFAGS----------
-------------------S
TRDVGP--------------
--------------SLGL--
-------KKSSSLESLQ---
-TAVAEVTLNGDLPFHRPRP
RIIRGRGC---NESFRAAID
--KSYDRPAAT---------
--------------------
---EEEDEGMETLEEDTEES
SRSGRDSVSTVADQT-----
-----------PLSGPE---
KPLVNGSARAKEEKKKDKDK
AGK----------EKKKQDG
GKDKDKDKDKGK--------
------AKKGMLKGLGDMFR
F------GKHRKDERPGDKM
DRKGSSRWRPEEAS---EEE
TMK-----------------
--------------------
--------------------
--MRMEQERIQAKTRELRER
QARER---------------
------------------DY
A-----EILDVSR-------
--------------------
--------------------
----------STERSYEEER
PHTGLSSSVDSGHSRP----
--HSPRDDPAPLGQSQ----
-----------HTDPLHTHV
GKGRSERPPSA---------
------------------DR
WVGWPTSGEQP--------R
PDTAAAA---------GVPA
GAGRRRRRRRRPPEDLQLR-
-----------------AAL
GSPGRNPAPP----------
--------------------
--------------------
-PRTPVDKAHPPGEGFQTAK
DNPRYSSYQ-----------
---GSRNGYASG-GVNARVL
LEAQELLRQEQRRR--EQEA
KGKLRQEG-----GYSGPKD
PVS--PKGPYRHDVPPSPSQ
LVRLN--------------R
LGS-EKGRLFYS--------
--------------------
--------------------
------
>gi_111186461_ref_NP_001034369.2_	Gallus
--------------------
--------------------
--------------------
-------MKVTVCFGRTRVV
VPCGDGNMKVFSLIQQAVTR
YKKAIAK-------------
--------------------
--------------------
---DPNYWIQVHRLEHGDGG
ILDLDDILCDVADDKDR---
--------------------
--------------------
--------------------
---------------LVAVF
DEQ-----DPHHGGDGTSA-
--SSTGTQSPEIFGSELGS-
------NAASAFQPYQATSE
IEVTPSVLRANMPLHVRRSS
DPALIGLS--------TSVS
DTNFSSEEPSRKN---PTRW
S-------------------
---TTAGFLKQNTPGVPTTH
DRK--KDENYRSLPRDTSSW
SN--QFQRDNARSSLSASHP
MVDKWLERQEQ--DEDRTEE
DNS-----RVEPVGHADTGL
ENNTNFSLDDMVKLVEV---
----SNDGGPLGIHVVPFSA
---------RGGRTLGLLVK
RLEKGGKAEQENLFCE--ND
CIVRINDGDLRNRRFEQAQH
MFRQAMRTPFIWFHVVPAAN
KEQYEQLSQSEKNM--YYSN
RFSPDSQYNDSKNIHNSGLH
TLQRMSR--AGNQSDQTESY
SQLPHSVNSSGKPPSGLVPS
PQKVLTSTANSGYNTKKIGK
RLSIQLRKGTEG--------
-------LGSSITSRDVPIG
--GSAPIYVTNILPRGAAIQ
DGRLKAGD--RLIEV-----
----------NGVDLTGKTQ
EEVVSLLRSTKMGGTVSLLI
FRQ-----------------
----EETFHPRELN------
--------------------
---------AEQSQSQIPKE
TKAEEEELVLTPDGTREFLT
FEVPLND--SGSAGLGVSVK
GNRSKENH----ADLGIFVK
SIINGGAASKDGRLRVNDQL
IAVNGESLLGKTN-QDAMET
LRRSMSTEGNKRGMIQLIVA
RRI---------------SK
CNELESPGSPSGPELP--IE
TLLDDRERRISHSLYSGIE-
GLSESPTRNAALS-------
-----------------RIM
G---KYQLSPTV--------
-----------NMPQDDTVI
IEDDRLSVLPPHLSDQSSSS
SH--DDVGLGTVDAGG----
---WAKAAINES--TDCTLS
PDVDP--------------V
LAFQRE----GFGRQSMSEK
-----RTKQFSDASQ-----
--------------------
---------------LE---
--FVKTRKSKSM----DL-V
ADETK--------------L
STMDDQKTGS----------
-------------------P
TRDVGP--------------
--------------SLGL--
-------KKSSSLESLQ---
-TAVAEVTLNGDIPFHRPRP
RIIRGRGC---NESFRAAID
--KSYDKPVA----------
--------------------
---DDDDEGMETLEEDTEES
SRSGRESVSTASDQP-----
-------------SHSL---
ERQMNGSQDKG---------
-------------DRKKAGK
EKKKDRDKEKDKIK------
------AKKGMLKGLGDMFR
F------GKHRKD----DKS
EKTGKIKVQEALTS---EEE
RIR-----------------
--------------------
--------------------
--MKQEQERIQAKTREFRER
QARER---------------
------------------DY
A-----EIQDFNR-------
--------------------
TFGCDADPMYAGISSY-DSS
SNSGTITLTSRPQS------
PREGQTV-------EALYAQ
VKKPWNSKSSPVDSNR----
-----------STPNNHDRI
QRLRQEFQQAK---------
-QDED---------------
------VEDRRRTYSFEQPW
PNSKTYSQSGRHSVS---VE
VQMQRQRQEERESFQQAQR-
---------------QYSSL
PRQSRKNASSV---------
--------------------
--------------------
-SQDSWEQSYSPGEGFQTAK
DNPRYSSYQ-----------
---GSRNGYMGGHGFNARVM
LETQELLRQEQRRK--EQQL
KKKTSSEGPSNYDSYKKIQD
PNYTPPKGPFRQDVPPSPSQ
VARLN--------------R
LQTPEKGRPFYS--------
--------------------
--------------------
------
>gi_114630035_ref_XP_001146208.1_	Pan
--------------------
--------------------
--------------------
-------MKVTVCFGRTRVV
VPCGDDHMKVFSLIQQAVTR
YRKAIAK-------------
--------------------
--------------------
---DPNYWIQVHRLEHGDGG
ILDLDDILCDVADDKDR---
--------------------
--------------------
--------------------
---------------LVAVF
DEQ-----DPHHGGDGTSA-
--SSTGTQSPEIFGSELGT-
------NNVSAFQPYQATSE
IEVTPSVLRANMPLHVRRSS
DPALIGLS--------TSVS
DSNF---PRKRKN---PTRW
S-------------------
---TXAGFXKQNTAGSPKTC
DRK--KDENYRSLPRDTSNW
SN--QFQRDNARSSLSASHP
MVGKWLEKQEQ--DEDGTEE
DNS-----RVEPVGHADTGL
EHIPNFSLDDMVKLVEV---
----PNDGGPLGIHVVPFSA
---------RGGRTLGLLVK
RLEKGGKAEHENLFHE--ND
CIVRINDGDLRNRRFEQAQH
MFRQAMRTPIIWFHVVPAAN
KEQYEQLSQSEKNN--YYSS
RFSPDSQYIDNRSVNSAGLH
TVQRAPR--LNHPPEQIDSH
SRLPHSAHPSGKPPSAPASA
PQNVFSTTVSSGYNTKKIGK
RLNIQLKKGTEG--------
-------LGFSITSRDVTIG
--GSAPIYVKNILPRGAAIQ
DGRLKAGD--RLIEV-----
----------NGVDLVGKSQ
EEVVSLLRSTKMEGTVSLLV
FRQ-----------------
----EDAFHPRELN------
--------------------
---------AEPSQMQIPKE
TKPEDEDIVLTPDGTREFLT
FEVPLND--SGSAGLGVSVK
GNRSKENH----ADLGIFVK
SIINGGAASKDGRLRVNDQL
IAVNGESLLGKTN-QDAMET
LRRSMSTEGNKRGMIQLIVA
RRI---------------SK
CNELKSPGSPPGPELP--IE
TALDDRERRISHSLYSGIE-
GLDESPSRNAALS-------
-----------------RIM
G---KYQLSPTV--------
-----------NMPQDDTVI
IEDDRLPVLPPHLSDQSSSS
SH--DDVGFVTADAGT----
---WAKAAISDS--ADCSLS
PDVDP--------------V
LAFQRE----GFGRQSMSEK
-----RTKQFSDASQ-----
--------------------
---------------LD---
--FVKTRKSKSM----DLGI
ADETK--------------L
STVDDPKAGS----------
-------------------P
SRDVGP--------------
--------------SLGL--
-------KKSSSLESLQ---
-TAVAEVTLNGDIPFHRPRP
RIIRGRGC---NESFRAAID
--KSYDKPAV----------
--------------------
---DDDDEGMETLEEDTEES
SRSGRESVSTASDQP-----
-------------SHSL---
ERQMNGNQEKGDKTDR----
-------------KKDKTGK
EKKKDRDKEKDKMK------
------AKKGMLKGLGDMFR
F------GKHRKD----DKI
EKTGKIKIQESFTS---EEE
RIR-----------------
--------------------
--------------------
--MKQEQERIQAKTREFRER
QARER---------------
------------------DY
A-----EIQDFHR-------
--------------------
TFGCDDELMYGGVSSY----
--EGSMALNARPQS------
PREGHMM-------DALYAQ
VKKPRNSKPSPVDSNR----
-----------STPSNHDRI
QRLRQEFQQAK---------
-QDED---------------
------VEDRRRTYSFEQPW
PNARPATQSGRHSVS---VE
VQMQRQRQEERESSQQAQR-
---------------QYSSL
PRQSRKNASSV---------
--------------------
--------------------
-SQDSWEQNYSPGEGFQSAK
ENPRYSSYQ-----------
---GSRNGYLGGHGFNARVM
LETQELLRQEQRRK--EQQM
KKQPPSEGPSNYDSYKKVQD
PSYAPPKGPFRQDVPPSPSQ
VARLN--------------R
LQTPEKGRPFYS--------
--------------------
--------------------
------
>NP_062565.2
--------------------
--------------------
--------------------
-------MKVTVCFGRTRVV
VPCGDGHMKVFSLIQQAVTR
YRKAIAK-------------
--------------------
--------------------
---DPNYWIQVHRLEHGDGG
ILDLDDILCDVADDKDR---
--------------------
--------------------
--------------------
---------------LVAVF
DEQ-----DPHHGGDGTSA-
--SSTGTQSPEIFGSELGT-
------NNVSAFQPYQATSE
IEVTPSVLRANMPLHVRRSS
DPALIGLS--------TSVS
DSNFSSEEPSRKN---PTRW
S-------------------
---TTAGFLKQNTAGSPKTC
DRK--KDENYRSLPRDTSNW
SN--QFQRDNARSSLSASHP
MVGKWLEKQEQ--DEDGTEE
DNS-----RVEPVGHADTGL
EHIPNFSLDDMVKLVEV---
----PNDGGPLGIHVVPFSA
---------RGGRTLGLLVK
RLEKGGKAEHENLFRE--ND
CIVRINDGDLRNRRFEQAQH
MFRQAMRTPIIWFHVVPAAN
KEQYEQLSQSEKNN--YYSS
RFSPDSQYIDNRSVNSAGLH
TVQRAPR--LNHPPEQIDSH
SRLPHSAHPSGKPPSAPASA
PQNVFSTTVSSGYNTKKIGK
RLNIQLKKGTEG--------
-------LGFSITSRDVTIG
--GSAPIYVKNILPRGAAIQ
DGRLKAGD--RLIEV-----
----------NGVDLVGKSQ
EEVVSLLRSTKMEGTVSLLV
FRQ-----------------
----EDAFHPRELN------
--------------------
---------AEPSQMQIPKE
TKAEDEDIVLTPDGTREFLT
FEVPLND--SGSAGLGVSVK
GNRSKENH----ADLGIFVK
SIINGGAASKDGRLRVNDQL
IAVNGESLLGKTN-QDAMET
LRRSMSTEGNKRGMIQLIVA
RRI---------------SK
CNELKSPGSPPGPELP--IE
TALDDRERRISHSLYSGIE-
GLDESPSRNAALS-------
-----------------RIM
GESGKYQLSPTV--------
-----------NMPQDDTVI
IEDDRLPVLPPHLSDQSSSS
SH--DDVGFVTADAGT----
---WAKAAISDS--ADCSLS
PDVDP--------------V
LAFQRE----GFGRQSMSEK
-----RTKQFSDASQ-----
--------------------
---------------LD---
--FVKTRKSKSM----DLGI
ADETK--------------L
NTVDDQKAGS----------
-------------------P
SRDVGP--------------
--------------SLGL--
-------KKSSSLESLQ---
-TAVAEVTLNGDIPFHRPRP
RIIRGRGC---NESFRAAID
--KSYDKPAV----------
--------------------
---DDDDEGMETLEEDTEES
SRSGRESVSTASDQP-----
-------------SHSL---
ERQMNGNQEKGDKTDR----
-------------KKDKTGK
EKKKDRDKEKDKMK------
------AKKGMLKGLGDMFR
F------GKHRKD----DKI
EKTGKIKIQESFTS---EEE
RIR-----------------
--------------------
--------------------
--MKQEQERIQAKTREFRER
QARER---------------
------------------DY
A-----EIQDFHR-------
--------------------
TFGCDDELMYGGVSSY----
--EGSMALNARPQS------
PREGHMM-------DALYAQ
VKKPRNSKPSPVDSNR----
-----------STPSNHDRI
QRLRQEFQQAK---------
-QDED---------------
------VEDRRRTYSFEQPW
PNARPATQSGRHSVS---VE
VQMQRQRQEERESSQQAQR-
---------------QYSSL
PRQSRKNASSV---------
--------------------
--------------------
-SQDSWEQNYSPGEGFQSAK
ENPRYSSYQ-----------
---GSRNGYLGGHGFNARVM
LETQELLRQEQRRK--EQQM
KKQPPSEGPSNYDSYKKVQD
PSYAPPKGPFRQDVPPSPSQ
VARLN--------------R
LQTPEKGRPFYS--------
--------------------
--------------------
------
>gi_149634757_ref_XP_001508605.1_	Ornithorhynchus
--------------------
--------------------
--------------------
--------------------
MNC-----------------
------Q-------------
--------------------
--------------------
---EPNYWIQVHRLEHGDGG
ILDLDDILCDVADDKDR---
--------------------
--------------------
--------------------
---------------LVAIF
DEQ-----DPHHGGDGTSA-
--SSTGTQSPEIFGSEMGA-
------NNVSAFQPYQAASE
IEVTPSVLRANMPLHVRRSS
DPALIGLS--------TSVS
ETNFSSEEPSRKN---PTRW
S-------------------
---TTAGFLKPNTSGSPSNR
DRK--KDENYRSLPRDTSNW
SN--QFQRDSARSSLSASHP
MVDTWLERQEQ--DEDGTEE
DNS-----RVEPVGHADTGL
ENTTNFSLDDMVKLVEV---
----SNDGGPLGIHVVPFSA
---------RGGRTLGLLVK
RLEKGGKAEQENLFHE--ND
CIVRINDGDLRNRRFEQAQH
MFRQAMRTPIIWFHVVPAAN
KEQYEQLSQSEKNN--YYAN
RFNPDTQYIDNKSVNSAGFH
ALQRIPR--LNNQAEQTDSY
SQLPHSVNLSGKLPSALAPA
QQNVLNANPNSGYSTKKIGK
RLSIQLKKGTEG--------
-------LGFSITSRDVPIG
--GSAPIYVKNILPRGAAIQ
DGRLKAGD--RLVEV-----
----------NGVDLTGKTQ
EEAVSLLRSTKMGGTVSLLV
FRQ-----------------
----EETFHPRELT------
--------------------
---------AEPSQTQIPKE
TKAEDDDLVLTPDGTREFLT
FEVPLND--SGSAGLGVSVK
GNRSKENH----ADLGIFVK
SIINGGAASKDGRLRVNDQL
IAVNGESLLGKTN-QDAMDT
LRRSMSTEGNKRGMIQLIVA
RRI---------------SK
CNELKSPGTPSGPELP--IE
TVLDDRERRISHSLYSGIE-
VLDESPTRNAALS-------
-----------------RIM
G---KYQLSPTV--------
-----------NMPQDDTVI
IEDDRLPVLPPHLSDQSSSS
SH--DDVGLATADAGP----
---WAKATISDS--ADCTLS
PDVDP--------------V
LAFQRE----GFGRQSMSEK
-----RTKQFSDASQ-----
--------------------
---------------LD---
--FVKTRKSKSM----DL-V
ADETK--------------L
NSVDDQKTGS----------
-------------------P
SRDIGP--------------
--------------SLGL--
-------KKSSSLESLQ---
-TAVAEVTLNGDIPFHRPRP
RIIRGRGC---NESFRAAID
--KSYDKPAA----------
--------------------
---DDDDEGMETLEEDTEES
SRSGRESVSTASDQP-----
-------------SHSL---
ERHMNGNQDKGDKTDR----
-------------KKDKTGK
EKKKDRDKEKDKMK------
------AKKGMLKGLGDMFR
F------GKHRKD----DKI
DKSGKIKVQEALTS---EEE
RIR-----------------
--------------------
--------------------
--MKQEQERIQAKTREFRER
QARER---------------
------------------DY
A-----EIQDFNR-------
--------------------
TFGCEDDSMYAGIPSY--DP
TNSGAATLNTRPQS------
PREGHTM-------EALYAQ
VKKPRNSKSSPLDSNR----
-----------STPSNHDRI
QRLRQEFQQAK---------
-QDED---------------
------GEDRRRTYSFEQPW
PNTKTYTQSGRHSVS---VE
VQMQRQRQEERESFQQAQR-
---------------QYSSL
PRQSRKNASSV---------
--------------------
--------------------
-SQDSWEQNYSPGEGFQSAK
ENPRYLSYQ-----------
---GSRNGYMGGHGFNARVM
LETQELLRQEQRRK--EQQL
KKKTSSDGPNSYDSYKKVQD
PNFTPPKGPFRQDVPPSPSQ
VARLN--------------R
LQTPEKGRPFYS--------
--------------------
--------------------
------
>gi_126341380_ref_XP_001374593.1_	Monodelphis
--------------------
--------------------
--------------------
-------MKVTVCFGRTRVV
VPCGDGNMKVSSLIEQAVTR
YKKAIAK-------------
--------------------
--------------------
---DPNYWIKVHRLEHGDGG
ILDLDDTLCDVADDKDR---
--------------------
--------------------
--------------------
---------------LVAIF
DEQ-----DPHHGGDGTSA-
--SSTGTQSPEIFGSELSA-
------NNVSAFQPYQAASE
IEVTPSVLRANMPLHVRRSS
DPALIGLA--------TSVS
DNNFSSEEPSRKN---PTRW
S-------------------
---TTAGFLKQNTSGSPNTR
DRK--KDENYRSLPRDTSNW
NN--QFQRDNARSSLSASHP
MVDKWLERQEQ--DEDGTEE
DNS-----RVEPVGHADTGL
ENTTNLSLDDMVKLVEV---
----SNDGGPLGIHVVPFSA
---------RGGRTLGLLVK
RLEKGGKAEQENLFHE--ND
CIVRINDGDLRNRRFEQAQH
MFRQAMRTPIIWFHVVPAAK
KEQYEQLSQSEKNN--YYSN
RFNPDAQYVDNKSVNSAGLS
ALQRIPR--LNHQADQTDSY
SQLPHNANISGKLPSTLSPT
QQNVLSPTPSSGYNTKKIGK
RLNIQLKKGSEG--------
-------LGFSITSRDVPVG
--GSAPIYVKNILPRGAAIQ
DGRLKAGD--RLVEV-----
----------NGVDLTGRTQ
EEVVSLLRSTKMGGTVSLLV
IRQ-----------------
----EEAFHPREMN------
--------------------
---------AEPSQMHIPKE
TKAEDEDLVLTPDGTREFLT
FEVPLND--SGSAGLGVSVK
GNRSKENH----ADLGIFVK
SIINGGAASKDGRLRVNDQL
IAVNGESLLGKTN-QDAMET
LRRSMSTEGNKRGMIQLIVA
RRI---------------NK
CNEVKSPGSPSGPELP--IE
TVLDDRERRISHSLYSGIE-
SLDESPTRNAALS-------
-----------------RIM
G---KYQLSPTV--------
-----------NMPQDDTVI
IEDDRLPVLPPHLSDQSSSS
SH--DDVGFATTDAGA----
---WAKATISDS--ADCSLS
PDADP--------------V
LTFQRE----GFGRQSMSEK
-----RTKQFSDASQ-----
--------------------
---------------LD---
--FVKTRKSKSM----DL-V
ADETK--------------L
STVDDQKTGS----------
-------------------P
SRDVGP--------------
--------------SLGL--
-------KKSSSLESLQ---
-TAVAEVTLNGDIPFHRPRP
RIIRGRGC---NESFRAAID
--KSYDKPAA----------
--------------------
---DEDDEGMETLEEDTEES
SRSGRESVSTASDQP-----
-------------SHSL---
ERQVNGNQENKTDRK-----
--------------KEKAGK
EKKKDRDKEKDKMK------
------AKKGMLKGLGDMFR
F------GKHRKD----DKI
EKSGKIKVQEALTS---EEE
RIR-----------------
--------------------
--------------------
--MKQEQERIQAKTREFRER
QARER---------------
------------------DY
A-----EIHDYNR-------
--------------------
PIGGEGDSSYAGMSSY-ETS
MNSGTMTFNVRPQS------
PREGQTT-------DALYAQ
VKKQRNSKPSPVDSNR----
-----------STPSNHDRI
QRLRQEFQQAK---------
-QDED---------------
------VEDRRRTYSFEQPW
PNTKIYTQSGRHSVS---VE
VQMQRQRQEERESFQQAQR-
---------------QYSSL
PRQSRKNTSSV---------
--------------------
--------------------
-SQDSWEQNYSPGEGFQSAK
ENPRYSSYQ-----------
---GSRNGYMGGHGFNARVM
LETQELLRQEQRRK--EQQL
KKKPPSDGPNNYDSYKKVQD
PNYGPPKGPFRQDVPPSPSQ
VARLN--------------R
LQTPEKGRPFYS--------
--------------------
--------------------
------
