>NP_705899.2
--------------------
--------------------
--------------------
--------------MSLGGA
SE-----RSV----------
--------------------
--------------------
--------------------
------------------PA
TKIEITVSCR----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDL
DTFSKSDPMVVLYTQS----
-----------RASQEWRE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------FGRTEVI
DNTLNPDFVRKFVLDYFFEE
KQNLRFDVYNVDS--KTN--
ISKPKDFLGQAFLALGE---
--------------------
--------------------
--------------------
------------VIGGQGSR
VERTL---------------
--------------------
--TGVPGKKCGTILLTAEEL
SNCR--DIATMQLCANKLDK
K-DFFG----KSDPFLVFYR
SNEDGTFT------------
-ICHKTEVVKNTLNPVWQPF
SIPVRALCNGDYDRTVKIDV
YDWDRDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTTSYRELSK---AQNQFTV
YEVLNPRKKCKK-KKYVNSG
TVTLLSFSVDSEFTFVDYIK
GGTQLNFTVAIDFTASNGNP
LQPTSLHYMSPYQLSAYAMA
LKAVGEIIQDYDSD------
-------------KLFPAYG
FGAKLP---PEGRISHQFPL
NNNDEDPNCAGIEGVLESYF
QSLRTVQLYGPTYFAPVINQ
VARA----------------
--------------------
--------------------
-----------------AAK
ISDGSQYYVLLIITDG---V
ISDMTQTKEAIVSASSLPMS
IIIVGVGPAMFEA--MEELD
GDDVRV-SSRGRYAERDIVQ
FVPFRDYVD----------R
SGNQVLSMARLAKDVLAEIP
EQLLS---YMRTRD------
------------IQPR----
------------PPPPA---
NPSPIPAPEQP---------
--------------------
--------------------
-
>NP_705898.1
--------------------
--------------------
--------------------
---------MDSRYNSTAGI
GDLNQLSAAI----------
--------------------
--------------------
--------------------
------------------PA
TRVEVSVSCR----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDR
DTFSKSDPICVLYVQG----
-----------VGNKEWRE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------FGRTEVI
DNTLNPDFVRKFILDYFFEE
RENLRFDLYDVDS--KSP--
NLSKHDFLGQVFCTLGE---
--------------------
--------------------
--------------------
------------IVGSQGSR
LEKPI---------------
--------------------
--VGIPGKKCGTIILTAEEL
NCCR--DAVLMQFCANKLDK
K-DFFG----KSDPFLVFYR
SNEDGSFT------------
-ICHKTEVVKNTLNPVWQAF
KISVRALCNGDYDRTIKVEV
YDWDRDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTTSYRELSR---GQSQFNV
YEVVNPKKKGKK-KKYTNSG
TVTLLSFLVETEVSFLDYIK
GGTQINFTVAIDFTASNGNP
AQPTSLHYMNPYQLNAYGMA
LKAVGEIVQDYDSD------
-------------KMFPALG
FGAKLP---PDGRISHEFAL
NGNPQNPYCDGIEGVMEAYY
RSLKSVQLYGPTNFAPVINH
VARY----------------
--------------------
--------------------
-----------------ASS
VKDGSQYFVLLIVTDG---V
ISDMAQTKESIVNASKLPMS
IIIVGVGPAEFDA--MVELD
GDDVRV-SSRGKYAERDIVQ
FVPFRDYID----------R
SGNHILSMARLAKDVLAEIP
EQFLS---YMRARG------
------------IKPS----
------------PAP-----
-PPY----TPPTHVLQTQI-
--------------------
--------------------
-
>gi_47228752_emb_CAG07484.1_	Tetraodon
--------------------
--------------------
--------------------
----------MDKVEATATV
RDFDPISGSV----------
--------------------
--------------------
--------------------
------------------PA
TKVEITVSCR---------W
VRGGWNGSGLLGGLGRVLDA
SLLFKSSPFWGSSDCGWWWE
RGKYTCILISDTSKKRGFMT
EILSEMADLGALCCR-----
--------------------
---------------NLLDR
DTFSKSDPLVVLYTQG----
-----------VECKQWRE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------FGRTEVI
DNTLNPDFVRKFILDYFFEE
KQNLRFDVYDIDS--KSP--
DLAKHDFLGQVHCTLGE---
--------------------
--------------------
--------------------
------------IVGSPASR
LEKSLGAVVSAVDSAGQSLV
PFSSR---------------
--VGIPGKKCGTIVLSAEEL
GNCTC-DCATMQFCANKLDK
K-DFFG----KSDPFMVFYR
SNEDGTFT------------
-ICHKTEVVKNTLNPVWQAF
SIPVRALCNGDYERTIKAEI
YDWDRDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTTSYKELCR---GQGQSNV
YEVMNAKKKLKK-KRYINSG
TVSLLSFSVESEHTFLDYIK
GGTQIHFTVAIDFTASNGNP
SQSTSLHYMNPYQMNAYAMA
LKAVGEIIQDYDSD------
-------------KMFPALG
FGAKLP---PDGRVSHEFPL
NGNTENPYCNGMEGILEAYH
QSLKTVQLYGPTNFSPVVNH
VARYERNYPSLRRGARSLYG
SQSAEHLQRGDAPVRDIKAA
GDNVSVSGAELMKRKKLIGC
SCEVKSGTYSTAYLVRYAAA
VQDGSQYFVLLIITDG---V
ISDMAQTKEAIVNAAKLPMS
IIIVGVGQAEFDA--MVELD
GDDIRI-SSRGKMAERDIVQ
FVPFRDYMD----------R
TGNHVLSMARLAKDVLAEIP
DQLIS---YMKSRA------
------------IKPS----
------------PVP-----
-PAYSTGTQPPSNPV-----
--------------------
--------------------
-
>gi_157821439_ref_NP_001101086.1_	Rattus
--------------------
--------------------
--------------------
----------MDQPEDMASL
SEFDSLAGSI----------
--------------------
--------------------
--------------------
------------------PA
TKVEITVSCR----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDK
DMFSKSDPLCVMYTQG----
-----------MENKQWRE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------FGRTEVI
DNTLNPDFVRKFIVDYFFEE
KQNLRFDLYDVDS--KSP--
DLSKHDFLGQAFCTLGE---
--------------------
--------------------
--------------------
------------IVGSSGSR
LEKPLTIGTFSLNSRTGKPM
PAVSN---------------
--GGVPGKKCGTIILSAEEL
SNCR--DVATMQFCANKLDK
K-DFFG----KSDPFLVFYR
SNEDGTFT------------
-ICHKTEVMKNTLNPVWQTF
SIPVRALCNGDYDRTIKVEV
YDWDRDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTTSYRELAR---GQSQFNI
YEVINPKKKMKK-KKYVNSG
TVTLLSFAVESESTFLDYIK
GGTQINFTVAIDFTASNGNP
SQSTSLHYMSPYQLNAYALA
LTAVGEIIQHYDSD------
-------------KMFPALG
FGAKLP---PDGRVSHEFPL
NGNQENPSCCGIDGILEAYH
SSLRTVQLYGPTNFAPVVTH
VARN----------------
--------------------
--------------------
-----------------AAA
VQDGSQYSVLLIITDG---V
ISDMAQTKEAIVNAAKLPMS
IIIVGVGQAEFDA--MVELD
GDDVRI-SSRGKLAERDIVQ
FVPFRDYVD----------R
TGNHVLSMARLARDVLAEIP
DQLVS---YMKAQG------
------------IRPR----
------------PPPAAPVQ
SPPQSPAHSPPGSPVHTHI-
--------------------
--------------------
-
>gi_119624317_gb_EAX03912.1_	Homo
--------------------
--------------------
--------------------
----------MEQPEDMASL
SEFDSLAGSI----------
--------------------
--------------------
--------------------
------------------PA
TKVEITVSCRLGTGAIFPDF
RESSSDLNNVDSVSRKRVGN
VCWMGKRGIYGAIWKSFVWE
QLREAEDGKQDTGETEALRD
GVSTCGIWTAAIRDIIGGSL
AATWINMASGALLQTYTARL
GTEPKELPFYTPGQGNLLDK
DMFSKSDPLCVMYTQG----
-----------MENKQWREE
CVHVLVIHEGKCGRALQKGT
LCPHSGTYVDGARMATFYNV
EEAGVGGPWPLRAPNEALKW
DSSAEIPLVFLPSLMGYKLG
LTGPGGFSDFKIQVLAFFPF
VIRPSNEGYKTSSFGRTEVI
DNTLNPDFVRKFIVDYFFEE
KQNLRFDLYDVDS--KSP--
DLSKHDFLGQAFCTLGE---
--------------------
--------------------
--------------------
------------IVGSPGSR
LEKPLTIGAFSLNSRTGKPM
PAVSN---------------
--GGVPGKKCGTIILSAEEL
SNCR--DVATMQFCANKLDK
K-DFFG----KSDPFLVFYR
SNEDGTFT------------
-ICHKTEVMKNTLNPVWQTF
SIPVRALCNGDYDRTIKVEV
YDWDRDGSYLTVSFIVSTWN
LPRLTLAFLYSFAWNSLLFC
ASWGQLPGATGSHHEVAHSQ
NAESCKYVDTIQCRLTVGGG
GVGPQGHLLGISLRLDAPGQ
HIDQGPLAVTGEVKGANPGV
SGSSAVYKSWPCLIHDFIGE
FTTSYRELAR---GQSQFNI
YEVVNPKKKMKK-KKYVNSG
TVTLLSFAVESECTFLDYIK
GGTQINFTVAIDFTASNGNP
SQSTSLHYMSPYQLNAYALA
LTAVGEIIQHYDSD------
-------------KMFPALG
FGAKLP---PDGRVSHEFPL
NGNQENPSCCGIDGILEAYH
RSLRTVQLYGPTNFAPVVTH
VARN----------------
--------------------
--------------------
-----------------AAA
VQDGSQYSVLLIITDG---V
ISDMAQTKEAIVNAAKLPMS
IIIVGVGQAEFDA--MVELD
GDDVRI-SSRGKLAERDIVQ
FVPFRDYVD----------R
TGNHVLSMARLARDVLAEIP
DQLVS---YMKAQG------
------------IRPR----
------------PPPAAPTH
SPSQSPARTPPASPLHTHI-
--------------------
--------------------
-
>gi_114607187_ref_XP_001173287.1_	Pan
--------------------
--------------------
--------------------
----------MEQPEDMASL
SEFDSLAGSI----------
--------------------
--------------------
--------------------
------------------PA
TKVEITVSCR----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDK
DMFSKSDPLCVMYTQG----
-----------MENKQWRE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------FGRTEVI
DNTLNPDFVRKFIVDYFFEE
KQNLRFDLYDVDS--KSP--
DLSKHDFLGQAFCTLGE---
--------------------
--------------------
--------------------
------------IVGSPGSR
LEKPLTIGAFSLNSRTGKPM
PAVSNGSGLWMESLRTTGLE
ASGGVPGKKCGTIILSAEEL
SNCR--DVATMQFCANKLDK
K-DFFG----KSDPFLVFYR
SNEDGTFT------------
-ICHKTEVMKNTLNPVWQTF
SIPVRALCNGDYDRTIKVEV
YDWDRDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTTSYRELAR---GQSQFNI
YEVVNPKKKMKK-KKYVNSG
TVTLLSFAVESECTFLDYIK
GGTQINFTVAIDFTASNGNP
SQSTSLHYMSPYQLNAYALA
LTAVGEIIQHYDSD------
-------------KMFPALG
FGAKLP---PDGRVSHEFPL
NGNQENPSCCGIDGILEAYH
RSLRTVQLYGPTNFAPVVTH
VARN----------------
--------------------
--------------------
-----------------AAA
VQDGSQYSVLLIITDG---V
ISDMAQTKEAIVNAAKLPMS
IIIVGVGQAEFDA--MVELD
GDDVRI-SSRGKLAERDIVQ
FVPFRDYVD----------R
TGNHVLSMARLARDVLAEIP
DQLVS---YMKAQG------
------------IRPR----
------------PPPAAPTH
SPSQSPARTPPASPLHTHI-
--------------------
--------------------
-
>NP_065990.1
--------------------
--------------------
--------------------
----------MEQPEDMASL
SEFDSLAGSI----------
--------------------
--------------------
--------------------
------------------PA
TKVEITVSCR----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDK
DMFSKSDPLCVMYTQG----
-----------MENKQWRE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------FGRTEVI
DNTLNPDFVRKFIVDYFFEE
KQNLRFDLYDVDS--KSP--
DLSKHDFLGQAFCTLGE---
--------------------
--------------------
--------------------
------------IVGSPGSR
LEKPLTIGAFSLNSRTGKPM
PAVSN---------------
--GGVPGKKCGTIILSAEEL
SNCR--DVATMQFCANKLDK
K-DFFG----KSDPFLVFYR
SNEDGTFT------------
-ICHKTEVMKNTLNPVWQTF
SIPVRALCNGDYDRTIKVEV
YDWDRDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTTSYRELAR---GQSQFNI
YEVVNPKKKMKK-KKYVNSG
TVTLLSFAVESECTFLDYIK
GGTQINFTVAIDFTASNGNP
SQSTSLHYMSPYQLNAYALA
LTAVGEIIQHYDSD------
-------------KMFPALG
FGAKLP---PDGRVSHEFPL
NGNQENPSCCGIDGILEAYH
RSLRTVQLYGPTNFAPVVTH
VARN----------------
--------------------
--------------------
-----------------AAA
VQDGSQYSVLLIITDG---V
ISDMAQTKEAIVNAAKLPMS
IIIVGVGQAEFDA--MVELD
GDDVRI-SSRGKLAERDIVQ
FVPFRDYVD----------R
TGNHVLSMARLARDVLAEIP
DQLVS---YMKAQG------
------------IRPR----
------------PPPAAPTH
SPSQSPARTPPASPLHTHI-
--------------------
--------------------
-
>gi_119915158_ref_XP_585264.3_	Bos
--------------------
--------------------
--------------------
----------MEQPEDMASL
SEFDSLAGSI----------
--------------------
--------------------
--------------------
------------------PA
TKVEITVSCR----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDK
DMFSKSDPLCVMYTQG----
-----------MENKQWRE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------FGRTEVI
DNTLNPDFVRKFIVDYFFEE
KQNLRFDLYDVDS--KSP--
DLSKHDFLGQAFCTLGE---
--------------------
--------------------
--------------------
------------IVGSPGSR
LEKSLTIGAFSLNSRTGKPM
PAVSN---------------
--GGVPGKKCGTIILSAEEL
SNCR--DVATMQFCANKLDK
K-DFFG----KSDPFLVFYR
SNEDGTFT------------
-ICHKTEVVKNTLNPVWQTF
SIPVRALCNGDYDRTIKVEV
YDWDRDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTTSYRELAR---GQSQFNI
YEVVNPKKKMKK-KKYVNSG
TVTLLSFAVESECTFLDYIK
GGTQINFTVAIDFTASNGNP
SQSTSLHYMSPYQLNAYALA
LTAVGEIIQHYDSD------
-------------KMFPALG
FGAKLP---PDGRVSHEFPL
NGNQENPSCCGIDGILEAYH
HSLRTVQLYGPTNFAPVVTH
VARN----------------
--------------------
--------------------
-----------------AAA
VQDGSQYSVLLIITDG---V
ISDMAQTKEAIVNAAKLPMS
IIIIGVGQAEFDA--MVELD
GDDVRI-SSRGKLAERDIVQ
FVPFRDYVD----------R
TGNHVLSMARLARDVLAEIP
DQLVS---YMKAQG------
------------IRPR----
------------SPPMATAR
SPPQSPARTPPASPLHTHI-
--------------------
--------------------
-
>gi_194040416_ref_XP_001927623.1_	Sus
--------------------
--------------------
---------------IAQGL
TNLGWGARWAMEQPEDMASL
SEFDSLAGSI----------
--------------------
--------------------
--------------------
------------------PA
TKVEITVSCR----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDK
DMFSKSDPLCVMYTQG----
-----------MENKQWRE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------FGRTEVI
DNTLNPDFVRKFIVDYFFEE
KQNLRFDLYDVDS--KSP--
DLSKHDFLGQAFCTLGE---
--------------------
--------------------
--------------------
------------IVGSPGSR
LEKSLTIGAFSLNSRTGKPM
PAVSN---------------
--GGVPGKKCGTIILSAEEL
SNCR--DVATMQFCANKLDK
K-DFFG----KSDPFLVFYR
SNEDGTFT------------
-ICHKTEVMKNTLNPVWQTF
SIPVRALCNGDYDRTIKVEV
YDWDRDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTTSYRELAR---GQSQFNI
YEVVNPKKKMKK-KKYVNSG
TVTLLSFAVESECTFLDYIK
GGTQINFTVAIDFTASNGNP
SQSTSLHYMSPYQLNAYALA
LTAVGEIIQHYDSD------
-------------KMFPALG
FGAKLP---PDGRVSHEFPL
NGNQENPSCCGIDGILEAYH
HSLRTVQLYGPTNFAPVVTH
VARN----------------
--------------------
--------------------
-----------------AAA
VQDGSQYSVLLIITDG---V
ISDMAQTKEAIVNAAKLPMS
IIIIGVGQAEFDA--MVELD
GDDVRI-SSRGKLAERDIVQ
FVPFRDYVD----------R
TGNHVLSMARLARDVLAEIP
DQLVS---YMKAQG------
------------IRPR----
------------APPTAPAR
SPPQSPTRTPPASPLHTHI-
--------------------
--------------------
-
>gi_148704346_gb_EDL36293.1_	Mus
--------------------
---------------WRQRL
EQRGSQGQGGRLQTGERRPP
LRAQVVCSFPHSAMSDPEMG
WVPEPPAMTL----------
--------------------
--------------------
--------------------
------------------GA
SRVELRVSCH----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------GLLDR
DTLTKPHP-CVLLKL-----
-----------YSDEQWVE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------VERTEVL
RSCSSPVFSRVLAIEYFFEE
KQPLQFHVFDAED--GAT--
SPSSDTFLGSTECTLGQ---
--------------------
--------------------
--------------------
------------IVSQT--K
VTKPLLLKN-----------
--------------------
--GKTAGK--STITIVAEEV
SGTN--DYVQLTFRAHKLDN
K-DLFS----KSDPFMEIYK
TNGDQSDQ------------
-LVWRTEVVKNNLNPSWEPF
RLSLHSLCSCDIHRPLKFLV
YDYDSSGK------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTSTFQEMQEGTANPGQEMQ
WDCINPKYRDKK-KNYKSSG
TVVLAQCTVEKVHTFLDYIM
GGCQISFTVAIDFTASNGDP
RSSQSLHCLSPRQPNHYLQA
LRTVGGICQDYDSD------
-------------KRFPAFG
FGARIP---PNFEVSHDFAI
NFDPENPECEEISGVIASYR
RCLPQIQLYGPTNVAPIINR
VAEPAQR-------------
--------------------
--------------------
-----------------EQS
TGQATKYSVLLVLTDG---V
VSDMAETRTAIVRASRLPMS
IIIVGVGNADFSD--MRLLD
GDDGPLRCPKGVPAARDIVQ
FVPFRDFKD-----------
-----AAPSALAKCVLAEVP
RQVVE---YYASQG------
------------ISPG----
-----------APRPSTPAM
TPSPSP--------------
--------------------
--------------------
-
>NP_006023.1
--------------------
--------------------
--------------------
-------------MSDPEMG
WVPEPPTMTL----------
--------------------
--------------------
--------------------
------------------GA
SRVELRVSCH----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------GLLDR
DTLTKPHP-CVLLKL-----
-----------YSDEQWVE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------VERTEVL
RSCSSPVFSRVLALEYFFEE
KQPLQFHVFDAED--GAT--
SPRNDTFLGSTECTLGQ---
--------------------
--------------------
--------------------
------------IVSQT--K
VTKPLLLKN-----------
--------------------
--GKTAGK--STITIVAEEV
SGTN--DYVQLTFRAYKLDN
K-DLFS----KSDPFMEIYK
TNEDQSDQ------------
-LVWRTEVVKNNLNPSWEPF
RLSLHSLCSCDVHRPLKFLV
YDYDSSGK------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTSTFQEMQEGTANPGQEMQ
WDCINPKYRDKK-KNYKSSG
TVVLAQCTVEKVHTFLDYIM
GGCQISFTVAIDFTASNGDP
RSSQSLHCLSPRQPNHYLQA
LRAVGGICQDYDSD------
-------------KRFPAFG
FGARIP---PNFEVSHDFAI
NFDPENPECEEISGVIASYR
RCLPQIQLYGPTNVAPIINR
VAEPAQR-------------
--------------------
--------------------
-----------------EQS
TGQATKYSVLLVLTDG---V
VSDMAETRTAIVRASRLPMS
IIIVGVGNADFSD--MRLLD
GDDGPLRCPRGVPAARDIVQ
FVPFRDFKD-----------
-----AAPSALAKCVLAEVP
RQVVE---YYASQG------
------------ISPG----
-----------APRPCTLAT
TPSPSP--------------
--------------------
--------------------
-
>gi_149632089_ref_XP_001514223.1_	Ornithorhynchus
--------------------
--------------------
--------------------
---------MKKMSNIYESA
ANTLGIFNSP----------
--------------------
--------------------
--------------------
------------------CL
TKVELRVACK----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------GISDR
DALSKPDP-CVILKM-----
-----------QSHGQWFE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------VDRTEVI
RTCINPIFSKLFTVDFYFEE
VQRLRFEVHDISS--NHN--
GLKEADFLGGMECTLGQ---
--------------------
--------------------
--------------------
------------IVSQR--K
LSKSLLKH------------
--------------------
--GNTAGK--SSITVIAEEL
SGND--DYVELSFNARKLDD
K-DFFS----KSDPFLEIFR
MNDDATQQ------------
-LVHRTEVVMNNLSPAWKAF
KVSVNSLCSGDQDRRLKCIV
WDWDSNGK------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTSTFKEMRG--AMEGRQVQ
WECINPKYKAKK-KNYKNSG
MVILNLCKIHKMHSFLDYIM
GGCQIQFTVAIDFTASNGDP
RNSCSLHYIHPYQPNEYLKA
LVAVGEICQDYDSD------
-------------KMFPAFG
FGARIP---PEYTVSHDFAI
NFNEDNPECAGIQGVVEAYQ
NCLPKLQLYGPTNIAPIIQK
VAKSASE-------------
--------------------
--------------------
-----------------ETN
TKEASQYFILLILTDG---V
ITDMADTREAIVHASHLPMS
VIIVGVGNADFSD--MQMLD
GDDGILRSPKGEPVLRDIVQ
FVPFRNFKHLAWMSFLGPAR
RLPRASSQAGLLEALLFEFE
KERVDDDDRLTGSSTIIQR-
------------VDPKFAVN
QR---------SQLHCSWGC
TERETLALTLGQCARLFKES
DE------------------
--------------------
-
>NP_570720.1
--------------------
--------------------
--------------------
---------MKKMSNIYESA
ANTLGIFNSP----------
--------------------
--------------------
--------------------
------------------CL
TKVELRVACK----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------GISDR
DALSKPDP-CVILKM-----
-----------QSHGQWFE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------VDRTEVI
RTCINPVYSKLFTVDFYFEE
VQRLRFEVHDISS--NHN--
GLKEADFLGGMECTLGQ---
--------------------
--------------------
--------------------
------------IVSQR--K
LSKSLLKH------------
--------------------
--GNTAGK--SSITVIAEEL
SGND--DYVELAFNARKLDD
K-DFFS----KSDPFLEIFR
MNDDATQQ------------
-LVHRTEVVMNNLSPAWKSF
KVSVNSLCSGDPDRRLKCIV
WDWDSNGK------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FTSTFKEMRG--AMEGKQVQ
WECINPKYKAKK-KNYKNSG
TVILNLCKIHKMHSFLDYIM
GGCQIQFTVAIDFTASNGDP
RNSCSLHYIHPYQPNEYLKA
LVAVGEICQDYDSD------
-------------KMFPAFG
FGARIP---PEYTVSHDFAI
NFNEDNPECAGIQGVVEAYQ
SCLPKLQLYGPTNIAPIIQK
VAKSASE-------------
--------------------
--------------------
-----------------ETN
TKEASQYFILLILTDG---V
ITDMADTREAIVHASHLPMS
VIIVGVGNADFSD--MQMLD
GDDGILRSPKGEPVLRDIVQ
FVPFRNFKH-----------
-----ASPAALAKSVLAEVP
NQVVD---YYNGKG------
------------IKPK----
------------CSSEMYES
SRTLAP--------------
--------------------
--------------------
-
>gi_194208911_ref_XP_001488332.2_	Equus
--------------------
--------------------
--------------------
-------------MRDTTP-
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------VEK
HPTSMQDM-GVGKNQ-----
-----------RGSHLFGQ-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------VDRTEVV
RSSLHPVFSKVFTLDYYFEE
VQRLRFEVYDTHG--PSSL-
SCQDDDFLGGMECTLGQ---
--------------------
--------------------
--------------------
------------IVAQK--K
MTRALLLKF-----------
--------------------
--GRHAGK--STITVIAEDI
SRNN--GYVELSFRARKLDD
K-DLFS----KSDPFLELYR
INDDQSEQ------------
-LVYRTEVVKNNLSPVWEPF
KVSLSSLCSCEEARTLKCLV
WDYDSRGK------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FSTTFEEMQK--AFREDQAQ
WDCVNAKYKQKK-RNYKNSG
VVILADLKFHRVYSFLDYIM
GGCQIHFTVAIDFTASNGDP
RNSRSLHYINPFQPNEYLQA
LVAVGEICQDYDSD------
-------------KRFSALG
FGARIP---PKYEVSHNFAI
NFDPEDDECEGIQGVVEAYQ
NCLPRVQLYGPTNVAPVISK
VACMAAA-------------
--------------------
--------------------
-----------------EEH
TGEASQYYILLILTDG---V
VTDMADTREAIVRASHLPMS
IIIVGVGNADFTD--MHVLD
GDDGVLRSPRGEPALRDIVQ
FVPFRELKN-----------
-----ASPAALAKCVLAEVP
KQVVE---FYSHKE------
------------LPPRWASE
AKDSR----SVSPTPRACPC
QPQSLPWLAGVGTGAARHRG
CAFFCCTKEARQEAVSKCCK
GTQDPSLAQSLSPHRDLNSC
-
>NP_055242.1
--------------------
--------------------
--------------------
----------MSAGSERGAA
ATPGGL-PAP----------
--------------------
--------------------
--------------------
------------------CA
SKVELRLSCR----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------HLLDR
DPLTKSDP-SVALLQ-----
-----------QAQGQWVQ-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------VGRTEVV
RSSLHPVFSKVFTVDYYFEE
VQRLRFEVYDTHG--PSGF-
SCQEDDFLGGMECTLGQPAQ
KWLLQVVMRVSVDVLGPAGH
CAKHFLCCTESSHLARTGPS
FLLRYDDLCLPWATAGAVRW
WTCRGGHTQGWQIVAQK--K
VTRPLLLKF-----------
--------------------
--GRNAGK--STITVIAEDI
SGNN--GYVELSFRARKLDD
K-DLFS----KSDPFLELYR
VNDDQGLQ------------
-LVYRTEVVKNNLNPVWEAF
KVSLSSLCSCEETRPLKCLV
WDYDSRGK------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FSTTFEEMQK--AFEEGQAQ
WDCVNPKYKQKR-RSYKNSG
VVVLADLKFHRVYSFLDYIM
GGCQIHFTVAIDFTASNGDP
RNSCSLHYINPYQPNEYLKA
LVSVGEICQDYDSD------
-------------KRFSALG
FGARIP---PKYEVSHDFAI
NFNPEDDECEGIQGVVEAYQ
NCLPRVQLYGPTNVAPIISK
VARVAAA-------------
--------------------
--------------------
-----------------EES
TGKASQYYILLILTDG---V
VTDMADTREAIVRASRLPMS
IIIVGVGNADFTD--MQVLD
GDDGVLRSPRGEPALRDIVQ
FVPFRELKN-----------
-----ASPAALAKCVLAEVP
KQVVE---YYSHRG------
------------LPPR----
-----------SLGVPAGEA
SPGCTP--------------
--------------------
--------------------
-
>NP_689940.3
--------------------
--------------------
--------------------
---------MAHIPSGGAPA
AGAAPMGPQY----------
--------------------
--------------------
--------------------
------------------CV
CKVELSVSGQ----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDR
DVTSKSDPFCVLFTE-----
------------NNGRWIE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------YDRTETA
INNLNPAFSKKFVLDYHFEE
VQKLKFALFDQDK--SSM--
RLDEHDFLGQFSCSLGT---
--------------------
--------------------
--------------------
------------IVSSK--K
ITRPLLLLN-----------
--------------------
--DKPAGK--GLITIAAQEL
SDNR---VITLSLAGRRLDK
K-DLFG----KSDPFLEFYK
PGDDGKWM------------
-LVHRTEVIKYTLDPVWKPF
TVPLVSLCDGDMEKPIQVMC
YDYDNDGG------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDFIGE
FQTSVSQMCE--ARDSVPLE
FECINPKKQRKK-KNYKNSG
IIILRSCKINRDYSFLDYIL
GGCQLMFTVGIDFTASNGNP
LDPSSLHYINPMGTNEYLSA
IWAVGQIIQDYDSD------
-------------KMFPALG
FGAQLP---PDWKVSHEFAI
NFNPTNPFCSGVDGIAQAYS
ACLPHIRFYGPTNFSPIVNH
VARFAAQ-------------
--------------------
--------------------
-----------------ATQ
QRTATQYFILLIITDG---V
ISDMEETRHAVVQASKLPMS
IIIVGVGNADFAA--MEFLD
GDSRMLRSHTGEEAARDIVQ
FVPFREFRN-----------
-----AAKETLAKAVLAELP
QQVVQ---YFKHKN------
------------LPPT----
------------------NS
EPA-----------------
--------------------
--------------------
-
>NP_003906.2
--------------------
--------------------
--------------------
--------------------
--MKMMHMAH----------
--------------------
--------------------
--------------------
------------------CV
TLVQLSISCD----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------HLIDK
DIGSKSDPLCVLLQD-----
-----------VGGGSWAE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------LGRTERV
RNCSSPEFSKTLQLEYRFET
VQKLRFGIYDIDN--KTP--
ELRDDDFLGGAECSLGQ---
--------------------
--------------------
--------------------
------------IVSSQ--V
LTLPLMLKP-----------
--------------------
--GKPAGR--GTITVSAQEL
KDNR---VVTMEVEARNLDK
K-DFLG----KSDPFLEFFR
QG-DGKWH------------
-LVYRSEVIKNNLNPTWKRF
SVPVQHFCGGNPSTPIQVQC
SDYDSDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDLIGT
FHTSLAQLQA------VPAE
FECIHPEKQQKK-KSYKNSG
TIRVKICRVETEYSFLDYVM
GGCQINFTVGVDFTGSNGDP
SSPDSLHYLSPTGVNEYLMA
LWSVGSVVQDYDSD------
-------------KLFPAFG
FGAQVP---PDWQVSHEFAL
NFNPSNPYCAGIQGIVDAYR
QALPQVRLYGPTNFAPIINH
VARFAAQ-------------
--------------------
--------------------
-----------------AAH
QGTASQYFMLLLLTDG---A
VTDVEATREAVVRASNLPMS
VIIVGVGGADFEA--MEQLD
ADGGPLHTRSGQAAARDIVQ
FVPYRRFQN-----------
-----APREALAQTVLAEVP
TQLVS---YFRAQG------
------------WAPL----
------------KPLPPSAK
DPAQAPQA------------
--------------------
--------------------
-
>gi_73999554_ref_XP_544163.2_	Canis
MRATKMHEKLENRFVARVAG
YMQHMGAVDTLPAIKSKPPG
RGGHGRGPVSSEGSGSQGCG
GTSGPRSRRPQPRPRPPATA
LESRGPGKTPRGKGTKRQSR
AASAMTYNSRPSRGAVVERR
TAKAAQALPEETTTPFPSCH
ASSEIEIEYYNMGLKLTTLT
SRISCLPDEPPAPEMAAQCV
TKVELNVSCD----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDM
DVGSKSDPLCVLFLN-----
-----------TSGQQWYE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------VDRTERI
KNCLNPTFSKTFIIDYYFEV
VQKLKFGIYDIDN--KTV--
ALSDDDFLGEFECTLGQ---
--------------------
--------------------
--------------------
------------IVSSK--K
LTRPLVLKN-----------
--------------------
--GRPAGK--GSITISAEEI
KDNR---VVLFEMEARKLDN
K-DLFG----KSDPYLEFHK
QTSDGNWL------------
-MVHRTEVIKNNLNPVWRPF
KISLNSLCYGDMDKTIKVEC
YDYDNDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDLIGT
FQTTMTKLKE--ASRNSPVE
FECINEKKRQKK-KSYKNSG
VISVKQCEITVECTFLDYIM
GGCQLNFTVGVDFTGSNGDP
RSPDSLHYISPNGVNEYLTA
IWSVGLVIQDYDAD------
-------------KMFPAFG
FGAQIP---PQWQVSHEFPM
NFNPSNPYCNGIQGIVEAYR
ACLPQIKLYGPTNFSPIINH
VARFAAA-------------
--------------------
--------------------
-----------------ATQ
QQTASQYFVLLIITDG---V
ITDLDETRQAIVNAAKLPMS
IIIVGVGGADFSA--MEFLD
GDGGSLRSPSGEVAIRDIVQ
FVPFRQFQN-----------
-----APKEALAQCVLAEIP
QQVVG---YFNTYKL-----
------------LPPK----
--------------------
NPAKK---------------
--------------------
--------------------
-
>NP_003900.1
--------------------
--------------------
--------------------
--------------------
------MAAQ----------
--------------------
--------------------
--------------------
------------------CV
TKVALNVSCA----------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------NLLDK
DIGSKSDPLCVLFLN-----
-----------TSGQQWYE-
--------------------
--------------------
--------------------
--------------------
--------------------
-------------VERTERI
KNCLNPQFSKTFIIDYYFEV
VQKLKFGVYDIDN--KTI--
ELSDDDFLGECECTLGQ---
--------------------
--------------------
--------------------
------------IVSSK--K
LTRPLVMKT-----------
--------------------
--GRPAGK--GSITISAEEI
KDNR---VVLFEMEARKLDN
K-DLFG----KSDPYLEFHK
QTSDGNWL------------
-MVHRTEVVKNNLNPVWRPF
KISLNSLCYGDMDKTIKVEC
YDYDNDGS------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------HDLIGT
FQTTMTKLKE--ASRSSPVE
FECINEKKRQKK-KSYKNSG
VISVKQCEITVECTFLDYIM
GGCQLNFTVGVDFTGSNGDP
RSPDSLHYISPNGVNEYLTA
LWSVGLVIQDYDAD------
-------------KMFPAFG
FGAQIP---PQWQVSHEFPM
NFNPSNPYCNGIQGIVEAYR
SCLPQIKLYGPTNFSPIINH
VARFAAA-------------
--------------------
--------------------
-----------------ATQ
QQTASQYFVLLIITDG---V
ITDLDETRQAIVNASRLPMS
IIIVGVGGADFSA--MEFLD
GDGGSLRSPLGEVAIRDIVQ
FVPFRQFQN-----------
-----APKEALAQCVLAEIP
QQVVG---YFNTYKL-----
------------LPPK----
------------NPATKQQK
Q-------------------
--------------------
--------------------
-
