>gi_55925560_ref_NP_001007331.1_	Danio
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---MAGNLKKG--GGLIGMM
KDAFQPHHHLHH---SHHQP
GAVD--KKTVEKC-----WK
FM------------------
-DKVVRLCQNPKLALKNSPP
YILDLLPDTYQHLRTILSRY
EG--KMETLGDNEYFRVFME
NLTKKTKQTISLFKDGKERM
FEENSQPRRNLTKLSLIFSH
MLAELKAIFPNGLFQGDNFR
ITKADAAEFWRRSFG-DKTI
VPWKVFRQALHEFHPISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWSSLLRNW
NSLAVTHPGYMAFLTYDEVK
ARLQKFIHKPG--SYIFRLS
CTRL----------------
GQWAIGYVTADGNILQTIPH
NKPLFQAHIDGFREGFYLFP
DGR-TQNPDLTGLCEPSPQD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESE-GQGCP
FCRCEIKGTEPIVVDPFDPK
DPNSAASYGCRGMFGAEGAP
SPSYDDDDDDRLEETPFMIS
KLVGSKV-------------
-------ERPPSPMSIS---
PQPVVPPVPPRLDLLPLRPT
NPPGASSPGATSKAPS--HH
KDKPLPLPPA-LRDLPPPPP
--PDRPHPAGADNRLPRRPL
PSTPGD-PSRDKLPPAPPNR
NMPDWNSRPV----PKAPSQ
PPASGDTR-GSRELSNRHSL
PLQLPSTLDSRTEAPRNNGP
PSLDHQLSFGSSNP-AS-DY
DS-PKVKPSASANAIYSLAI
RPVAAARTQTGEETNE-NDE
ESEYMTPSSR------PVLP
SAAG------EAVPRPPPPL
SLSPRSMLNELE-SESPQMY
EAMYNIQAQALTASAPQARD
SDYSELPPLTCSNGPRDPVG
AYAEEEEEE-----------
-----------ENSYDYPKP
HLSAAL---ARRTLSD----
----ANSPSSSAF-------
--------------------
--------------------
SRLSFDSDLGAAATVLDPSE
APERPPKPLPRRINSDRR-P
SPVPPGASPG------PSQQ
ISSEIEHLLSQGYSHQDIQK
ALMIAQNNIEMAKNVLREFV
SIPSTAHILT--
>gi_62201339_gb_AAH93450.1_	Xenopus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------ISPSQPGAHREG
CVRGPRVHQPQEFHPAAPRS
LVTMATNLRKG--GGLIGLV
KDAFQPHHHH-----PTAQP
GAVD--RKTVEKC-----WK
LM------------------
-DKVVRLCQNQRLALKNSPP
YILDLLPDTYQHLRTIMSRY
EG--KMEILGENEYFRVFME
NLLKKTKQTISLFKEGKERM
YEENSQPRRNLTKLSLIFSH
MLAELKAIFPNGQFQGDSFR
ITKADAAEFWRKAFG-EKTI
VPWKIFRLALHDVHPISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWSSLLRNW
NSLAVTHPGYMAFLTYDEVK
ARLQKFIHKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGFREGFYLFP
DGR-NQNPDLTGLCEPTPQD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTSWQ-ESE-GQGCP
FCRCEIKGTEPIVVDPFDPR
GGGMA----ELLRHCMDGTP
SPCYDDDDDDSGNDSIFVMK
ELAGAKV-------------
-------ERPPSPLSAT---
PQASLPPVPPRLDLLPQRAP
NQSGACSPATSSKASSSSHH
KDKPLPVPPT-LRDLPPPPP
--PDRPHSMPCESRPQRRPL
PSTPAEKP-----LPLPTNR
PGETWHPRAV----PKAPAS
NLTPGDPWTGGRELTNRHSL
PFTLPSHIDER--RDRHGST
QSLDNTGISATTELFGGLDN
DD-AKMKPSSSANAIYSLAT
RPFPVSKPPTGDHVDS--GD
ESEYMCPSSR------PLIP
AAVP------KSEARRPLET
LPGLRPPDQ--Q--TERESY
ETMYNIQCQA--TNPVVVEP
SREEETNSAIANNGPENDDN
E-------------------
-----------EDGYDIPKP
HLPMAP---ARRTMSD----
----APNATPAFC-------
--------------------
--------------------
-SGAIGRDSGAGLL--ESSQ
VPERPPKPFPRRMNSERR--
SVVGGGSGDA------PPAP
LSSEIESLLSQGYSQQDVNK
ALLIAHNNIEMARNILREFV
SIPSPAHVAT--
>gi_126326907_ref_XP_001380505.1_	Monodelphis
MSFQCVHFAILGALTRVLPL
RLPPGCAQTFARRKLALSLR
VEEYRGGGLKVVCIH-----
--------------------
--------------------
-------------------A
LLPLATPLPNLSLKRRARAR
AGMRVPAIPTPSADRPRPSL
FRAPPPALPSGPTLRPVPES
RWLRPAEGGSASVPGGIPPR
CPEPPPDMVRNEKKGAGPGG
----TAAPGAPVSADIIRPH
EGPAKYYFFHEVFSRNAKRY
NSGEYIRSLFNKDG---KWN
VLCEKQQQNQGVKFKKTGKV
GEQVVRLCQNPKLALKNSPP
YILDLLPDTYQHLRTILSRY
EG--RMETLGENEYFRVFME
NLMKKTKQTISLFKEGKERM
YEENSQPRRNLTKLSLIFSH
MLAELKGIFPSGLFQGDTFR
ITKADAAEFWRKAFG-EKTI
VPWKSFRQALHEVHPISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWSSLLRNW
NSLAVTHPGYMAFLTYDEVK
ARLQKFIHKPG--SYIFRLS
CTRL----------------
GQWAIGYVTADGNILQTIPH
NKPLFQALIDGFREGFYLFP
DGR-NQNPDLTGLCEPTPQD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESE-GQGCP
FCRCEIKGTEPIVVDPFDPR
GGGG------LLRQGAEGAP
SPNYDDDDDERADDSLFMMK
ELACAKV-------------
-------ERPPSPFSMA---
PQASLPPVPPRLDLLQQRTS
NPSGASSPGTSSKTTPGSLH
KDKPLPIPPT-LRDLPPPPP
--PDRPHSIGAESRPQRRPL
PCTPGDCPSRDKLPPVPSGR
PGESWLPRPI----PKVPTA
TLSPGDPWSG-RELTNRHSL
PFSLPSQMDPRTDGLRHGST
FSLDAPVNMNNNPL-VGPEC
EH-PKIKPSSSANAIYSLAA
RPLPVPKLPLGEQCGN--DE
DTEYMSPSSR------PL--
--VLPVVNLQKIDVKRPLET
THSLHVFDSEQQ--VDSCTY
EAMYNIQSQA--TSGLEIST
SVEGDLATTLASNGPEESEN
E-------------------
-----------DDGYDVPKP
PVPAVL---ARRTLSD----
----ISNASSSFS-------
--------------------
--------------------
-WMSLDGDPTTGFT--EGSQ
VPERPPKPFPRRINSERKAG
SCQQAGAAPS------TSPQ
LSSEIESLMSQGYSYQDIQK
ALVIAHNNIEMAKNILREFV
SISSPAHVAT--
>gi_109483387_ref_XP_576396.2_	Rattus
--------------------
----------------MAKG
RGGSSGRGNLVEAFR-----
--------------------
--------------------
-------------------E
PQGTRVLASSCASWGVAAAF
RARLSPARAPALRRPRSRPR
RGAPQGGRLPLTPSAVSAGG
GCRRGPSFSPRSIPSLAAER
APDPPLAMAGNVKKSSGAGG
----SGSGGSG-AGGLIGLM
KDAFQPHHHHHHH-LSPHPP
CTVD--KKMVEKC-----WK
LM------------------
-DKVVRLCQNPKLALKNSPP
YILDLLPDTYQHLRTVLSRY
EG--KMETLGENEYFRVFME
NLMKKTKQTISLFKEGKERM
YEENSQPRRNLTKLSLIFSH
MLAELKGIFPSGLFQGDTFR
ITKADAAEFWRKAFG-EKTI
VPWKSFRQALHEVHPISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWSSLLRNW
NSLAVTHPGYMAFLTYDEVK
ARLQKFIHKPG--SYIFRLS
CTRL----------------
GQWAIGYVTADGNILQTIPH
NKPLFQALIDGFREGFYLFP
DGR-NQNPDLTGLCEPTPQD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTSWQ-ESE-GQGCP
FCRCEIKGTEPIVVDPFDPR
GSGS------LLRQGAEGAP
SPNYDDDDDERADDSLFMMK
ELAGAKV-------------
-------ERPSSPFSMA---
PQASLPPVPPRLDLLQQRAP
VPASTSVLGTASKASSSSLH
KDKPLPIPPT-LRDLPPPPP
--PDRPYSVGTETRPQRRPL
PCTPGDCPSRDKLPPVPSSR
PGDSWLSRPI----PKVPVA
TPNPGDPWNG-RELTNRHSL
PFSLPSQMEPRADVPRLGST
FSLDTSTTMNSSPV-AGPES
EH-PKIKPSSSANAIYSLAA
RPLPVPKLPPGEQGDS--EE
DTEYMTPTSR------PV--
--GV-----QKPEPKRPAET
AQSSRACDCDQQ--IDSCTY
EAMYNIQSQA--LSVAENSA
CGEGNLATAHTSTGPEESEN
E-------------------
-----------DDGYDVPKP
PVPAVL---ARRTLSD----
----ISNASSSFG-------
--------------------
--------------------
-WLSLDGEP-TNFN--EGSQ
VPERPPKPFPRRINSERKAS
SYQQGGGAMANPAAAAPSPQ
LSSEIERLMSQGYSYQDIQK
ALVIAHNNIEMAKNILREFV
SISSPAHVAT--
>gi_109108973_ref_XP_001104812.1_	Macaca
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-------MAGNVKKSSGAGG
---GGGSGGSG-SGGLIGLM
KDAFQPHHHHHHHHLSPHPP
GTVD--KKMVEKC-----WK
LM------------------
-DKVVRLCQNPKLALKNSPP
YILDLLPDTYQHLRTILSRY
EG--KMETLGENEYFRVFME
NLMKKTKQTISLFKEGKERM
YEENSQPRRNLTKLSLIFSH
MLAELKGIFPSGLFQGDTFR
ITKADAAEFWRKAFG-EKTI
VPWKSFRQALHEVHPISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWSSLLRNW
NSLAVTHPGYMAFLTYDEVK
ARLQKFIHKPG--SYIFRLS
CTRL----------------
GQWAIGYVTADGNILQTIPH
NKPLFQALIDGFREGFYLFP
DGR-NQNPDLTGLCEPTPQD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTSWQ-ESE-GQGCP
FCRCEIKGTEPIVVDPFDPR
GSGS------LLRQGAEGAP
SPNYDDDDDERADDTLFMMK
ELAGAKV-------------
-------ERPPSPFSMA---
PQASLPPVPPRLDLLPQRVC
VPSSASALGTASKAASGSLH
KDKPLPVPPT-LRDLPPPPP
--PDRPYSVGTESRPQRRPL
PCTPGDCPSRDKLPPVPSSR
LGDSWLPRPI----PKVPVS
APSSSDPWTG-RELTNRHSL
PFSLPSQMEPRPDVPRLGST
FSLDTSMSMNSSPL-VGPEC
DH-PKIKPSSSANAIYSLAA
RPLPVPKLPPGEQCEG--EE
DTEYMTPSSR------PL--
---------------RPLDT
SQSSRACDCDQQ--IDTCTY
EAMYNIQSQA--PSVTESST
FGEGSLAAAHANTGPEEPEN
E-------------------
-----------DDGYDVPKP
PVPAVL---ARRTLSD----
----ISNASSSFG-------
--------------------
--------------------
-WLSLDGDPTTNVT--EVSQ
VPERPPKPFPRRINSERKAG
SWQQGSGAAA--SAATASPQ
LSSEIENLMSQGYSYQDIQK
ALVIAQNNIEMAKNILREFV
SISSPAHVAT--
>NP_005179.2
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-------MAGNVKKSSGAGG
---GSGSGGSG-SGGLIGLM
KDAFQPHHHHHHH-LSPHPP
GTVD--KKMVEKC-----WK
LM------------------
-DKVVRLCQNPKLALKNSPP
YILDLLPDTYQHLRTILSRY
EG--KMETLGENEYFRVFME
NLMKKTKQTISLFKEGKERM
YEENSQPRRNLTKLSLIFSH
MLAELKGIFPSGLFQGDTFR
ITKADAAEFWRKAFG-EKTI
VPWKSFRQALHEVHPISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWSSLLRNW
NSLAVTHPGYMAFLTYDEVK
ARLQKFIHKPG--SYIFRLS
CTRL----------------
GQWAIGYVTADGNILQTIPH
NKPLFQALIDGFREGFYLFP
DGR-NQNPDLTGLCEPTPQD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTSWQ-ESE-GQGCP
FCRCEIKGTEPIVVDPFDPR
GSGS------LLRQGAEGAP
SPNYDDDDDERADDTLFMMK
ELAGAKV-------------
-------ERPPSPFSMA---
PQASLPPVPPRLDLLPQRVC
VPSSASALGTASKAASGSLH
KDKPLPVPPT-LRDLPPPPP
--PDRPYSVGAESRPQRRPL
PCTPGDCPSRDKLPPVPSSR
LGDSWLPRPI----PKVPVS
APSSSDPWTG-RELTNRHSL
PFSLPSQMEPRPDVPRLGST
FSLDTSMSMNSSPL-VGPEC
DH-PKIKPSSSANAIYSLAA
RPLPVPKLPPGEQCEG--EE
DTEYMTPSSR------PL--
---------------RPLDT
SQSSRACDCDQQ--IDSCTY
EAMYNIQSQA--PSITESST
FGEGNLAAAHANTGPEESEN
E-------------------
-----------DDGYDVPKP
PVPAVL---ARRTLSD----
----ISNASSSFG-------
--------------------
--------------------
-WLSLDGDPTTNVT--EGSQ
VPERPPKPFPRRINSERKAG
SCQQGSGPAA--SAATASPQ
LSSEIENLMSQGYSYQDIQK
ALVIAQNNIEMAKNILREFV
SISSPAHVAT--
>gi_47223807_emb_CAF98577.1_	Tetraodon
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MATALNGRNPGG
---RGPNRSKGRILGIIDAI
QDAVGP-----------PKQ
PAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPRLQLKNSPP
YILDILPDAYQHLRLILGKY
EENQRLTQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPGGQFQGDTFR
ITKAEAADFWRNFFG-EKTI
VPWKVFRQCLHDVHPISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLHKYNNKPG--SYIFRLS
CTRL----------------
GQWAIGYVTSDGSILQTIPH
NKPLFLALIDGYREGFYLFP
DGR-SYNPDLTGLCQPTTHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDIKIEPCGHL
MCTLCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
NEGAK----CF-FLDQHSCP
MLELDDDEDR---DDCLVMN
GLANMRKHCAERQNSPMVSP
SSSPVSQHRKAHGGELGHCV
QHLGLPPVPPRLDLIQKSAM
RSPSASPTCSPKSSPGMSRK
QDKPLPAPPPPQRD-PPPPP
LPPERPPPIPPESRHSWFPS
SSSSSSGTSLESQKKS----
--DTPCPKDSHLDAP-----
-LGLGGP-------SHLNGR
PVSCPSAGFGRLPHRTDGGG
TP-ESSKPVSNGVQ-QSDDY
DVPP--SRHSPTQSLLSS--
CQTPANSFSTAVVGQE--EG
EDDYQVPSSSLCLRQAPV--
--CI-------SVPQRYSQC
VLLTKLIGNNVSKYVENSSS
LPSDEEKQP----QVLEPG-
-------------GPSEPTR
ASA-SGPKHSVICPFTSNTS
DYDILLPPQAIEDPFQSCPP
SGPPPPPPPMRHSFIDLSSS
SFSSPSSPCNSSSSSALTRP
HRPSSGQDQLLLTPDTVLDM
LSSAAPLPPVRRHT-ENVKG
SRGRLEYDHIPAHA--GCLQ
APARPPKPLPRTQ-------
-PGKSHSPES--------EN
VDAKIAKLMGEGYSFEDVKR
ALMIAQYKVDVARNILREF-
---VLVVPRLNI
>gi_147899744_ref_NP_001085428.1_	Xenopus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------MAS
GSGSSSSTSSSALSGRLPGS
---RSANPRKARILGLFDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLIKKSKRAMRLFKEGKERM
YEEQSQERRNLTKLSLIFSH
MLAEIKAIFPSGQFQGDNFR
ITKADAAEFWRKFFG-ERTI
VPWKIFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSLKPG--SYIFRLS
CTRL----------------
GQWAIGYVTADGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTSWQ-ESD-GQGCP
FCRCEIKGMEPIIVDPFDPR
DE-SR----CFSFSDSLCTP
MLDFDDDDLR---EECLIMN
RLAALRK-MNERQNSPVTSP
GSSPLSQRRKTPPEPLQ--I
PHLNLPPVPPRLDLIQKGLA
RSPCASPTGSPKSSPCMVRK
QDKPLPAPPPLLRE--PPPP
--PERPPPIPPDSRTCRH--
LHHADNVPCRDQSTPH----
--EAWCTRDLSGGNPASVCR
VTHDGSPKLGVPSSSVLNGR
HSRMSTEAGFMRHKHHKRRE
SPLETLRVY-NGLS-GNEEY
DVPPRLSPP--TITIHPIVK
CPV-LVNSVSDKVRNSAEED
DCEYKIPSSH------PV--
--S-------SRLPLHCHSI
KHFPRLCENGQC--LSNGTH
NGISEIKKL----KPPD---
--QGDVIATSTVPIHFPPAR
TSARENHPHG--SSLTRTPS
DYDLLVPHPG-EESFDISPP
SQPPPPPP-ARTCVTE----
----HVMPTALGS-------
-RPNSDVDLFLPHSDP----
-CPEAPLPPARRGPGE-VKS
NRLSQEYDQLPSCP--GKGQ
EKA-----------------
--------------------
---------------SNTKG
ELLLPNQNL-----IMRPT-
------------
>gi_224044401_ref_XP_002192985.1_	Taeniopygia
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSLNGRNP--
--------RKGRILGFIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAADFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISI
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLFP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DENSR----CCSILDSFSMP
MLDLDDDDDR---EESLMMN
RLASVRK-CNDRQNSPVTSP
GSSPLAQRRKPLPDPLQ--I
PHLSLPPVPPRLDLIQKGVA
RSPCASPTGSPKSSPCMVRK
QDKPLPAPPPPLRD-PPPPP
--PERPPPMLPESRSGRH--
LHHGENLPAREQPVPL----
--EAWCPRDVFGTSQ--GCQ
ARGDASPKAGLTATANLNGR
HGRVAS--EQGFMRKHRRHE
PPAESAKVFSNGHL-MSEEY
DVPPRLSPPLPAGSVIPSIK
CPGPSANSLSDKSREHL-DD
DDEYKIPSSH------PV--
--IL------SSQPPHGHNI
KPLARVCENGQC---TNGTH
GATSETKKS----KHPES--
---GDVCAAPSVPVPLPPAR
APARDNPKHS--TLLTRTPS
DYDLLVPPLG-EDAFDNSPP
SLPPPPPP-ARHSMIE----
----HTKPAGSGS-------
-RPSSGHELFLH-SDPHFDP
TIGHVPLPPARRAPGENVKT
NRTSQDYDQLPPSS--DGSQ
APARPPKPLPRRTAPEIH--
-HRKPYSSDS------STEN
VDAKIAKLMGEGYSFEEVKR
ALEIAQNNVDVARSILREFV
CFPPPVSPRLNL
>gi_118083608_ref_XP_416621.2_	Gallus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSQNGRNP--
--------RKGRILGFIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAADFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISI
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLFP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DENSR----CCSIIDSFSMP
MLDLDDDDDR---EESLMMN
RLASVRK-CNERQNSPVTSP
GSSPLSQRRKPLPDPLQ--I
PHLSLPPVPPRLDLIQKGVA
RSPCASPTGSPKSSPCMVRK
QDKPLPAPPPPLRD-PPPPP
--PERPPPIPPDNRISRH--
SHHPESVPSRDQPMPL----
--EGWCPRDVFGTSQLVGSR
TGSDTSPKPGLTAVSNINGR
HNRISS--EQGFMRKHRRHE
LPVEGAKVFSNGHL-INEEY
DVPPRLSPPLPGASTIPSIK
CPVSSANSLSDKSRDHT-DD
DDEYKVPPSH------SI--
--IL------SSQPPHCHNI
KAVARVCENGQCAGVTNGTH
SATSDVKKS----KHPEL--
---GDVYDAPTVPVPLPPAR
PPTRDNPKHS--SLLNRTPS
DYDLLVPPLG-EDAFDSSPP
SLPPPPPPPARHSITE----
----HTKPSGSGS-------
-RPPSGHELFLHP-DPHFDP
MTGHVPLPPVRRVTGENVKT
NRTSQDYDQLPPSS--DGSQ
APARPPKPLPRRTAPEIH--
-HRKAFNSDS------STEN
VDAKIAKLMGEGYSFEEVKR
ALEIAQNNVDVARSILREFV
CFPPPVSPRLNL
>gi_149445038_ref_XP_001514020.1_	Ornithorhynchus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSTNGRNPGG
---RGGNPRKGRILGIIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAAEFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISI
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DESSR----CCSIIDAFSMP
MLDLDDDDDR---EESLMMN
RLASVRK-CNDRQNSPVTSP
GSSPLAQRRKPLPDPLQ--I
PHLSLPPVPPRLDLIQKGVV
RSPCASPTGSPKSSPCMMRK
QDKPLPAPPPPLRE-PPPPP
--PERPPPIPPDPRISRH--
SHHPESVPSRDLPMPL----
--EAWCPRDAFGASQLLGCR
IVGDCSPKPGVTASSNVNGR
HNRVGS--DPVFVRKHRRHD
LPVEGSKVFSNGHL-GSEEY
DIPPRLSPPTSTASLHPSVK
CPIPLMNSLSDKLRETVEEG
GDEYKIPSSH------PI--
--SM------GSQSSHCHSI
KPPIRTCENGQC--LTNGTH
GTSSEMKKS----NLPELGI
YTKGDAFDSATVSVPLPPAR
PITRDNPKHG--PALNRTPS
DYDLLVPPLG-DDAFDSLPP
SLPPPPPP-ARHSLTE----
----HTKPVGSGS-------
-RPSSGQDIFLPPSDHFFDS
ASGLVPLPPARRLAGENVKA
NRTSQEYDQLPSAS--D-VQ
APARPPKPVPRKIAPEIH--
-HRKAFGPES------ALEN
VDAKIAKLMGEGYSFEEVKR
ALEIAQNNVDVARSILREF-
AFPPPVSPRLNL
>gi_118344448_ref_NP_001028410.1_	Mus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSMNGRNPGG
---RGGNPRKGRILGIIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAAEFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DEGSR----CCSIIDPFSIP
MLDLDDDDDR---EESLMMN
RLASVRK-CTDRQNSPVTSP
GSSPLAQRRKPQPDPLQ--I
PHLSLPPVPPRLDLIQKGIV
RSPCGSPTGSPKSSPCMVRK
QDKPLPAPPPPLRD--PPPP
--PERPPPIPPDNRLSRH--
FHHGESVPSRDQPMPL----
--EAWCPRDAFGTNQVMGCR
ILGDGSPKPGVTANSSLNGR
HSRMGS--EQVLMRKHRRHD
LPSEGAKVFSNGHL-ATEEY
DVPPRLSPPPPVTTLLPSIK
CTGPLANCLSEKTRDTVEDD
DDEYKIPSSH------PV--
--SL------NSQPSHCHNV
KAPVRSCDNGHC--ILNGTH
GAPSEMKKS----NIPDLGI
YLKG----------------
--------------------
-----------EDAFDALPP
SLPPPPPP-ARHSLIE----
----HSKPPGSSS-------
-RPSSGQDLFLLPSDPFFDP
TSGQVPLPPARRAAGDSGKA
NRASQDYDQLPSSS--DGSQ
APARPPKPRPRRTAPEIH--
-HRKPHGPEA------ALEN
VDAKIAKLMGEGYAFEEVKR
ALEIAQNNVEVARSILREF-
AFPPPVSPRLNL
>gi_149731341_ref_XP_001503404.1_	Equus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSMNGRNPGG
---RGGNPRKGRILGIIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDTFR
ITKADAAEFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DEGSR----CCSIIDPFGMP
MLDLDDDDDR---EESLMMN
RLANVRK-CTDRQNSPVTSP
GSSPLAQRRKPHPDPLQ--I
PHLSLPPVPPRLDLIQKGIV
RSPCGSPTGSPKSSPCMVRK
QDKPLPAPPPPLRD-PPPPP
--PERPPPVPPDNRLSRH--
FHHMESVPSRDQPMPL----
--EAWCPRDVFGTNQSVGCR
LLGDGSPKPGITASSNVNGR
HSRMGT--DPVLIRKHRRHD
LPAEGAKVFSNGHL-GSEEY
DVPPRLSPPPPATTLLPSIK
CTGPLANSLSEKTRDPAEEE
DEEYKVPSSH------PV--
--PL------NSQPSHCHNL
KPSLRSCDNGHC--ILNGTH
GTSSEMKKS----NIPELGI
YLKGDVFDSASDPVPLPPAR
PPTRDSPKHG--SSLNRTPS
DYDLLIPPLG-EDAFDALPP
SLPPPPPP-ARHSLVE----
----HSKPSGSSS-------
-RPSSGQELFLLPSDPFFDS
ASNQVPLPPARRLPGENVKS
NRTSQDYDQLPSSA--DGSQ
APARPPKPRPRRTAPEVH--
-HRKPHGPEA------ALEN
VDAKIAKLMGEGYAFEEVKR
ALEIAQNNVEVARSILREF-
AFPPPVSPRLNL
>gi_114588318_ref_XP_516635.2_	Pan
MGSTSLHQGRAVTALRKFIG
RYALEAESMAPGKQSGVIPR
ERDRSQVNLKIWDWRLGDDA
NAIRTGEIRNVLIVTEWVSP
IYGHSAFSPTPSDPLSTRPL
GGPSSGAIVYCGGRGRGGSA
RRTGASRPLAAPAVGQCAVA
RHWLSGARPRPRPAPPRPEP
GSCVCHRGGVSSERSPPPAS
AAAASRGLPESGGRGERVWI
CLDELKFQMANSMNGRNPGG
---RGGNPRKGRILGIIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAAEFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DEGSR----CCSIIDPFGMP
MLDLDDDDDR---EESLMMN
RLANVRK-CTDRQNSPVTSP
GSSPLAQRRKPQPDPLQ--I
PHLSLPPVPPRLDLIQKGIV
RSPCGSPTGSPKSSPCMVRK
QDKPLPAPPPPLRD-PPPPP
--PERPPPIPPDNRLSRH--
IHQVESVPSRDPPMPL----
--EAWCPRDVFGTNQLVGCR
LLGEGSPKPGITASSNVNGR
HSRVGS--DPVLMRKHRRHD
LPLEGAKVFSNGHL-GSEEY
DVPPRLSPPPPVTTLLPSIK
CTGPLANSLSEKTRDPVEED
DDEYKIPSSH------PV--
--SL------NSQPSHCHNV
KPPVRSCDNGHC--MLNGTH
GPSSE-KKS----NIPDLSI
YLKG----------------
--------------------
-----------EDAFDALPP
SLPPPPPP-ARHSLIE----
----HSKPPGSSS-------
-RPSSGQDLFLLPSDPFVDL
ASGQVPLPPARRLPGENVKT
NRTSQDYDQLPSCS--DGSQ
APARPPKPRPRRTAPEIH--
-HRKPHGPEA------ALEN
VDAKIAKLMGEGYAFEEVKR
ALEIAQNNVEVARSILREF-
AFPPPVSPRLNL
>gi_23273909_gb_AAH32851.1_	Homo
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSMNGRNPGG
---RGGNPRKGRILGIIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAAEFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DEGSR----CCSIIDPFGMP
MLDLDDDDDR---EESLMMN
RLANVRK-CTDRQNSPVTSP
GSSPLAQRRKPQPDPLQ--I
PHLSLPPVPPRLDLIQKGIV
RSPCGSPTGSPKSSPCMVRK
QDKPLPAPPPPLRD-PPPPP
--PERPPPIPPDNRLSRH--
IHHVESVPSKDPPMPL----
--EAWCPRDVFGTNQLVGCR
LLGEGSPKPGITASSNVNGR
HSRVGS--DPVLMRKHRRHD
LPLEGAKVFSNGHL-GSEEY
DVPPRLSPPPPVTTLLPSIK
CTGPLANSLSEKTRDPVEED
DDEYKIPSSH------PV--
--SL------NSQPSHCHNV
KPPVRSCDNGHC--MLNGTH
GPSSE-KKS----NIPDLSI
YLKGDVFDSASDPVPLPPAR
PPTRDNPKHG--SSLNRTPS
DYDLLIPPLG-EDAFDALPP
SLPPPPPP-ARHSLIE----
----HSKPPGSSS-------
-RPSSGQDLFLLPSDPFVDL
ASGQVPLPPARRLPGENVKT
NRTSQDYDQLPSCS--DGSQ
APARPPKPRPRRTAPEIH--
-HRKPHGPEA------ALEN
VDAKIAKLMGEGYAFEEVKR
ALEIAQNNVEVARSILREF-
AFPPPVSPRLNL
>NP_733762.2
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSMNGRNPGG
---RGGNPRKGRILGIIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAAEFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DEGSR----CCSIIDPFGMP
MLDLDDDDDR---EESLMMN
RLANVRK-CTDRQNSPVTSP
GSSPLAQRRKPQPDPLQ--I
PHLSLPPVPPRLDLIQKGIV
RSPCGSPTGSPKSSPCMVRK
QDKPLPAPPPPLRD-PPPPP
--PERPPPIPPDNRLSRH--
IHHVESVPSRDPPMPL----
--EAWCPRDVFGTNQLVGCR
LLGEGSPKPGITASSNVNGR
HSRVGS--DPVLMRKHRRHD
LPLEGAKVFSNGHL-GSEEY
DVPPRLSPPPPVTTLLPSIK
CTGPLANSLSEKTRDPVEED
DDEYKIPSSH------PV--
--SL------NSQPSHCHNV
KPPVRSCDNGHC--MLNGTH
GPSSE-KKS----NIPDLSI
YLKGDVFDSASDPVPLPPAR
PPTRDNPKHG--SSLNRTPS
DYDLLIPPLG-EDAFDALPP
SLPPPPPP-ARHSLIE----
----HSKPPGSSS-------
-RPSSGQDLFLLPSDPFVDL
ASGQVPLPPARRLPGENVKT
NRTSQDYDQLPSCS--DGSQ
APARPPKPRPRRTAPEIH--
-HRKPHGPEA------ALEN
VDAKIAKLMGEGYAFEEVKR
ALEIAQNNVEVARSILREF-
AFPPPVSPRLNL
>gi_119879341_ref_XP_604265.3_	Bos
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSMNGRNPGG
---RGGNPRKGRILGIIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAAEFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DEGSR----CCSIIDPFGMP
MLDLDDDDDR---EESLMMN
RLANVRK-CTDRQNSPVTSP
GSSPLAQRRKPHPDPLQ--I
PHLSLPPVPPRLDLIQKGIV
RSPCGSPTGSPKSSPCMVRK
QDKPLPAPPPPLRD-PPPPP
--PERPPPVPPDNRLSRH--
FHHVESVPSRDQPMPL----
--EAWCPRDVLGTNQSVGCR
LLGDGSPKPGITASSNANGR
HSRMGS--DPVLLRKHRRND
LPLEGAKVFSNGHL-GSEEY
DVPPRLSPPPPAATLLPSIK
CTGPLANSLSEKTRDPVEED
DDEYKVPSSH------PV--
--SL------SSQPSHCHNV
KPPPRSCDNGHC--ILNGTH
GTSSEMKKS----NIPELGI
YLKGDVFDSASDPVPLPPAR
PPTRDNPKHG--SSLNRTPS
DYDLLIPPLG-EDAFDALPP
SLPPPPPP-ARHSLIE----
----HSKPPGSGS-------
-RPSSGQDLFLLPSDPFFDP
ASGQVPLPPARRLPGENVKS
NRASQDYDPLPSSS--DGSQ
APARPPKPRPRRTAPEIH--
-HRKPHGPEA------ALEN
VDAKIAKLMGEGYAFEEVKR
ALEIAQNNVEVARSILREF-
AFPPPVSPRLNL
>gi_74002510_ref_XP_545087.2_	Canis
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------MANSMNGRNPGG
---RGGNPRKGRILGIIDAI
QDAVGP-----------PKQ
AAAD--RRTVEKT-----WK
LM------------------
-DKVVRLCQNPKLQLKNSPP
YILDILPDTYQHLRLILSKY
DDNQKLAQLSENEYFKIYID
SLMKKSKRAIRLFKEGKERM
YEEQSQDRRNLTKLSLIFSH
MLAEIKAIFPNGQFQGDNFR
ITKADAAEFWRKFFG-DKTI
VPWKVFRQCLHEVHQISSG-
LEAMALKSTIDLTCNDYISV
FEFDIFTRLFQPWGSILRNW
NFLAVTHPGYMAFLTYDEVK
ARLQKYSTKPG--SYIFRLS
CTRL----------------
GQWAIGYVTGDGNILQTIPH
NKPLFQALIDGSREGFYLYP
DGR-SYNPDLTGLCEPTPHD
HIKVTQEQYELYCEMGSTFQ
LCKICAENDKDVKIEPCGHL
MCTSCLTAWQ-ESD-GQGCP
FCRCEIKGTEPIIVDPFDPR
DEGSR----CCSIIDPFGMP
MLDLDDDDDR---EESLMMN
RLANVRK-CTDRQNSPVTSP
GSSPLAQRRKPHPDPLQ--I
PHLSLPPVPPRLDLIQKGIV
RSPCGSPTGSPKSSPCMVRK
QDKPLPAPPPPLRD-PPPPP
--PERPPPIPPDNRLSRH--
FHHVESVPSRDQPMPL----
--EAWCPRDVFGTNQSVGCR
QLGDGSPKPGITASSNVNGR
HSRMGS--DPVLLRKHRRHD
LPLEGAKVFSNGHL-GSEEY
DVPPRLSPPPPAATLVPSIK
CTGPLANPLSEKTRDPVEED
DDEYKIPSSH------PV--
--SL------NSQPSHCHNV
KPPLRSCDNGHC--VLNGTH
GTSSEVKKS----NIPELGI
YLKGDVFDSASDPVPLPPAR
PPTRDNPKHG--SSLNRTPS
DYDLLIPPLG-EDAFDALPP
SLPPPPPP-ARHSLIE----
----HSKPPGSNS-------
-RPSSGQDLFLLPSDPFFDP
VSGQVPLPPARRLPGENVKS
NRTSQDYDQLPSAS--DGSQ
APARPPKPRPRRTAPEVQ--
-HRKPHGPEA------ASEN
VDAKIAKLMGEGYAFEEVKR
ALEIAQNNVEVARSILREF-
AYPPPVSPRLHL
