>NP_056981.2
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
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--------------------
--------------------
--------------------
--------------------
--------------------
----------------MAAE
LVEA-------KNMVMSFR-
--VSDLQMLLGFVGRSKSGL
KHELVTRALQLVQFD-CSPE
LFKKIKELYETRYAKKNSEP
A----PQPHRPL--DPLTMH
---------S------TYDR
--------AGAVPRT-PLAG
PNIDYPVLYGKYLNGLGRLP
A--------KTLKPEVRLVK
LPFFNMLDELLKPTELVPQN
N-----EKLQESPCIFALTP
RQVELIRN---SRELQPGVK
A---VQVVLRICYSDTSCPQ
--------------------
--------EDQYPPNIAVKV
NHSYCSVPGYYPSNKPGVEP
KRPCRPINLTHLMY--LSSA
T-NRITVTWGNY-GKSYS--
VALYLVRQLTSSELLQRLKT
--IGVKHPELCKALVKEKLR
LDP-----------------
-------DSEIATTGVRVSL
ICPLVKMRLSVPCRAETCAH
LQCFDAVFYLQMNEKKPTWM
CPVCDKPAPYDQLIID--GL
LSKILSECE--DADEIEYLV
DGSWCPIRAEKERSCSPQG-
--------------------
--------------------
----AILVLGPSDANGLLPA
PSVNGS-GALGSTGGGGPVG
SMENGKPGADVVDLTLDSSS
SS------------------
--------------------
------EDE---EEEEEEEE
DEDEEGPRPKRRCPF-----
-------QKG----------
----L---------------
--------------------
--------------------
-------VPAC---------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>NP_004662.2
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
--------------------
--------------------
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--------------------
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--------------------
--------------------
-----------------MAD
FEEL-------RNMVSSFR-
--VSELQVLLGFAGRNKSGR
KHDLLMRALHLLKSG-CSPA
VQIKIRELYRRRYPRTLEGL
SDLSTIKSSVFS--LDGGSS
---------PVE-PDLAVAG
IH------SLPSTSVTPHSP
SSPVGSVLLQDTKPTF-EMQ
Q---PSPPIPPVHPDVQLKN
LPFYDVLDVLIKPTSLVQSS
I-----QRFQEKFFIFALTP
QQVREICI---SRDFLPGGR
RDYTVQVQLRLCLAETSCPQ
--------------------
--------EDNYPNSLCIKV
NGKLFPLPGYAPPPKNGIEQ
KRPGRPLNITSLVR--LSSA
VPNQISISWASEIGKNYS--
MSVYLVRQLTSAMLLQRLKM
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
MCPLGKMRLTIPCRAVTCTH
LQCFDAALYLQMNEKKPTWI
CPVCDKKAAYESLILD--GL
FMEILNDCS--DVDEIKFQE
DGSWCPMRPKKE--------
--------------------
--------------------
----AMKVSSQP-CTKIESS
SVLSKP-CSVTVASEAS---
-----KKKVDVIDLTIESSS
--------------------
--------------------
--------D---EEED----
------PPAKRKCIFMSETQ
SSP----TKG----------
----VLM------------Y
QPSS----------------
--------------------
-V-RVPSVTSVDPAAI---P
PSLTDYSVPFH----HTPIS
SMSSDLP-------------
--------GLDFLSLIPVDP
--------------------
------------QY--CPPM
FLDSLTSPLTA---------
------SSTSVTTTSS-HES
STHVSSSSSRSETGVITSSG
SNIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_71894815_ref_NP_001025797.1_	Gallus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
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--------------------
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--------------------
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--------------------
--------------------
--------------------
-----------------MAD
FEEL-------RNMVSSFR-
--VSELQVLLGFAGRNKSGR
KHDLLMRALHLLKSG-CSPA
VQIKIRELYRRRYPRTIEGL
SDLSAIKPAVFS--LDSSSS
---------PVE-PDLAVAG
IH------PLPSTSVTPQSP
SSPVSSVLLQDTKAHF-EMQ
Q---PSPPIPPVHPDVQLKS
LPFYDVLDVLIKPTSLVQSS
I-----QRFQEKFFIFALTP
QQVREICI---SRDFLPGGR
RDYTVQVQLRLCLAETSCPQ
--------------------
--------EDNYPNSLCIKV
NGKLFPLPGYAPPPKNGIEQ
KRPGRPLNITSLVR--LSSA
VPNQISISWASEIGKSYS--
MSVYLVRQLTSAMLLQRLKM
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
MCPLGKMRLTIPCRAVTCTH
LQCFDAALYLQMNEKKPTWI
CPVCDKKAAYESLILD--GL
FMEILNECS--DVDEIKFQE
DGSWCPMRPKKD--------
--------------------
--------------------
----AVKVSSPQ-CTKIESS
SVVSKP-CSVTVANEVN---
-----KKKVDVIDLTIESSS
--------------------
--------------------
--------D---EEED----
------PPAKRKCIFMSETQ
GSP----TKG----------
----VLM------------Y
QPSS----------------
--------------------
-V-RVPSVTTVDTAAI---P
PSLTDYPVPFH----HPPMS
SISSDLP-------------
--------GLDFLSLIPVES
--------------------
------------QY--CPPM
FLDSLTSTLTS-NTPG----
--------SIITSTSH-HES
NTH-VSSSNRSETGVITSSS
GSAPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_224088294_ref_XP_002193528.1_	Taeniopygia
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
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--------------------
--------------------
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--------------------
--------------------
--------------------
-----------------MAD
FEEL-------RNMVSSFR-
--VSELQVLLGFAGRNKSGR
KHDLLMRALHLLKSG-CSPA
VQIKIRELYRRRYPRTIEGL
SDLSAIKPAAFN--LDSSSS
---------PVE-PDLAVAG
IH------PLPSTSVTPQSP
SSPVSSVLLQDTKPHF-EMQ
Q---PSPPIPPVHPDVQLKS
LPFYDVLDVLIKPTSLVQSS
I-----QRFQEKFFIFALTP
QQVREICI---SRDFLPGGR
RDYTVQVQLRLCLAETSCPQ
--------------------
--------EDNYPNSLCIKV
NGKLFPLPGYAPPPKNGIEQ
KRPGRPLNITSLVR--LSSA
VPNQISISWASEIGKNYS--
MSVYLVRQLTSAMLLQRLKM
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
MCPLGKMRLTIPCRAVTCTH
LQCFDAALYLQMNEKKPTWI
CPVCDKKAAYESLILD--GL
FMEILNECS--DVDEIKFQE
DGSWCPMRPKKE--------
--------------------
--------------------
----AVKVSSPQ-CTKIESS
SVVSKP-CSVTVASEVN---
------KKVDVIDLTVESSS
--------------------
--------------------
--------D---EEED----
------PPAKRKCIFMSEIH
GSP----TKG----------
----VLM------------Y
QPST----------------
--------------------
-A-RVPSVTTVDAAAI---P
PSLTDYPVPFH----HPPIS
SISSDLP-------------
--------GLDVLSLFPVDS
--------------------
------------QY--CPPM
FLDSLTSTLTS-STPG----
--------SIITSTSH-HES
STH-VSSSGRAEAGVIT-SS
GGAPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_109015278_ref_XP_001095153.1_	Macaca
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
--------------------
--------------------
--------------------
--------------------
--------MQGAGLCGLIPR
GVGQKHPGGSEEGPALVNRD
KNRTKLWGGGGYINDSKKGS
GGAWGDRQCCSSLGWAGGGD
DADLMV----AKHMVMSFR-
--VSELQVLLGFAGRNKSGR
KHELLAKALHLLKSS-CAPS
VQMKIKELYRRRFPRKTLGP
SDLSLLS-------LPPGTS
---------PVGSPGPLA--
--------PIPPTLLAPGT-
-------LLGP-KREV-DMH
-----PSLAQPVHPDVTMKP
LPFYEVYGELIRPTTLASTS
S-----QRFEEAHFTFALTP
QQVQQILT---SREVLPGAK
CDYTIQVQLRFCLCETSCPQ
--------------------
--------EDYFPPNLFVKV
NGKLCPLPGYLPPTKNGAEP
KRPSRPINITPLAR--LSAT
VPNTIVVNWSSEFGRNYS--
LSVYLVRQLTAGTLLQKLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEVATTSLRVSL
MCPLGKMRLTVPCRALTCAH
LQSFDAALYLQMNEKKPTWT
CPVCDKKAPYESLIID--GL
FMEILSSCS--DCDEIQFME
DGSWCPMKPKKE--------
--------------------
--------------------
----ASEVCPPPGY-GLD-G
-LQYSP-VQEGNPSENK---
------KKVEVIDLTIESSS
--------------------
--------------------
--------D---EEDL----
------PPTKKHCSVTSAA-
-IPALPGSKG----------
----VLT----------SGH
QPSS----------------
--------------------
-VLRSPAMGALGGDFL--SS
LPLHEYPPAF-------P--
-LGADIQ-------------
--------GLDLFSFLQTES
-QHYGPSVITSL-------D
EQDA-L--GHFFQYRGTPSH
FLGPLAPTLGSSHRSA--TP
APPPGRVSSIVAPGGALREG
HGGPLPSGPS--------LT
GCRSDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>NP_006090.2
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
--------------------
-----------------MAE
LGEL-------KHMVMSFR-
--VSELQVLLGFAGRNKSGR
KHELLAKALHLLKSS-CAPS
VQMKIKELYRRRFPRKTLGP
SDLSLLS-------LPPGTS
---------PVGSPGPLA--
--------PIPPTLLAPGT-
-------LLGP-KREV-DMH
-----PPLPQPVHPDVTMKP
LPFYEVYGELIRPTTLASTS
S-----QRFEEAHFTFALTP
QQVQQILT---SREVLPGAK
CDYTIQVQLRFCLCETSCPQ
--------------------
--------EDYFPPNLFVKV
NGKLCPLPGYLPPTKNGAEP
KRPSRPINITPLAR--LSAT
VPNTIVVNWSSEFGRNYS--
LSVYLVRQLTAGTLLQKLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEVATTSLRVSL
MCPLGKMRLTVPCRALTCAH
LQSFDAALYLQMNEKKPTWT
CPVCDKKAPYESLIID--GL
FMEILSSCS--DCDEIQFME
DGSWCPMKPKKE--------
--------------------
--------------------
----ASEVCPPPGY-GLD-G
-LQYSP-VQGGDPSENK---
------KKVEVIDLTIESSS
--------------------
--------------------
--------D---EEDL----
------PPTKKHCSVTSAA-
-IPALPGSKG----------
----VLT----------SGH
QPSS----------------
--------------------
-VLRSPAMGTLGGDFL--SS
LPLHEYPPAF-------P--
-LGADIQ-------------
--------GLDLFSFLQTES
-QHYGPSVITSL-------D
EQDA-L--GHFFQYRGTPSH
FLGPLAPTLGSSHCSA--TP
APPPGRVSSIVAPGGALREG
HGGPLPSGPS--------LT
GCRSDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_47230681_emb_CAF99874.1_	Tetraodon
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
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--------------------
--------------------
--------------------
--------------------
-----------QQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKTG-CSPD
VHMKIKELYRRRFPAKMVSH
PELVMPGPH-----HPATVG
MVGGGGAALPAGLTQLTYEG
-HAGHGGAPSPAALL-PLS-
-------LLGPGKHELTGLT
HHLSPSATLHPVHPDVKLQR
LPFYDMLDELIKPTSLASDS
S-----QRYQETCLAFALTP
QQVQQISS---SMDIS-GTK
CDFSVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPSLCVKV
NGKPCNLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTSEIGRSYS--
MAVYLVKQQSSSVLLQRLRS
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLMIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FVEILNSCT--ECDEIQFKE
DGSWAPMKSKKE--------
--------------------
--------------------
----VQEVSAAPYNNGLDDS
-CQTSAGPDHRSPSSSSHSG
SDSSNGKKVEVIDLTVDSSS
--------------------
--------------------
--------E---DEGQDSPP
PPPPLPPAPKRACPSMSPT-
-SP-PVVNKGDARATRPDVP
AVCWILCPQGVEHAPPGFPR
QPHSQ---------------
--------------------
HAGRGPRLHASGPAPHPGLP
ALLPHAQRPVRAELLLFPPR
RQSSALQHGDGGGGGGGSGG
FILRRPRAAAQPFPALQHHI
LLLFLPAVPQPNRGLLCHVA
ERAL-QRGGKRGRR-RRPGV
FGEPPRRPLGV-LVPA--LG
LTLCAHTPRGGGQPGQRRGG
RGGHLRRDPRRHLVG---LT
G--PG---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_125843427_ref_XP_688159.2_	Danio
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
-----------------MAE
SAEL-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKTG-CSPA
VQMKIKELYRRRFPTKMVSP
TDLSLPGIHSSSG-GASAGL
---------PASLTQLGYDG
-H-------GSPSLL-PVA-
-------LLGP-KHEL-GLP
H---LPSALHPVHPDVKLQR
LPFYDVLDELIKPTSLASDN
S-----QRFQETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NGKPCNLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTSEIGRSYS--
MAVYLVRQQSSSVLLQRLRS
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLMIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILSSCV--DCDEIQFKE
DGNWSPMRSKKI--------
--------------------
--------------------
----VQEVSAS--SNGVEDS
-CRSVL-SDHRNSSSHS---
-SS--SKKVEVIDLTLDSSS
--------------------
--------------------
--------DE--DDSDE---
------PAPKRACPSLSPT-
-SP--PINKG----------
----VLN----------LHH
QASP----------------
--------------------
-LARAPSMPAMETNYIPPPP
PLIQDYRHYYH---------
-TPNDLS-------------
--------DLNFFSFLQGDN
HQHYNMVMAAAAAASASASA
SEDHELLLNRFMPY-GSSQL
FLEQSGTPASSSLVPANGSG
GSSSGSSSSLVSSSSL-RDS
HPHTNTSRSRSDAAASV-IY
GSIPDVISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_147906733_ref_NP_001079161.1_	Xenopus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
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--------------------
--------------------
--------------------
--------------------
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--------------------
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--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------MAD
SAEL-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKTG-CSPA
VQMKIKELYRRRFPLKILTP
ADFTLPSVHSSS--MPVNLS
---------PSSIPQLSYDG
-H------PASSPLL-PVT-
-------LL-P-KHEL-DLP
H---LTSNLHPVHPDVKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFQETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NGKPCNLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIARHFS--
LAVYLVKQLSSAILLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRSLTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKCCT--DCDEIQFKE
DGSWSPMRSKKE--------
--------------------
--------------------
----VQEVTTS--YNGVDNG
-CISSS-VEHQVPSNHH---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PCPKRSCPSITPA-
-SP--LSNKS----------
----MLN----------LQH
QASP----------------
--------------------
-ISRTPSLPPVDSTYI--NA
PLLQDYRHPFH----MAH--
-MPYDLQ-------------
--------GLDFFPFLSGEN
-QHYNTSLLAAAAAAAS--E
EPDL-LHSSRFFPY-TSSQL
FLDQLNASASS-SLPA--TN
GSNSGSNSSLVSSNSL-RES
HNAP--SRGPADSSS---LY
GIIPDVISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_149414673_ref_XP_001516107.1_	Ornithorhynchus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------------------ML
ANLSYLELEFEATLLFKLER
DVASHVSARGHPEKRGTRGF
LIGSGPGSRLPKLGRPSPSR
GPPTAPRAGEAPLLSALKRP
KTTAPGREKRVSAHLLVCPL
FGNG-------MQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSAIPQLAYDG
-H------PATSPLL-PVS-
-------LLGP-KHEL-ELP
H---LASALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NGKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRNYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKCCT--DCDEIQFKE
DGSWAPMRSKKE--------
--------------------
--------------------
----IQEVTAS--YNGVD-G
-CLSSS-LDHQVSSHQQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------EEEEEEEEE---
------PSAKRTCPSVSPA-
-SP--LNNKG----------
----ILN----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDPSYI--NT
SLIQDYRHPFH----MTP--
-MSYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVSASD
EQDL-LHSSRFFPY-ASSQM
FLDQLNAGGSTATLPT--TN
GSSSGSNSSLVSSNSL-REN
HGHPVANRSGTDTAS---IF
GIMPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_126277525_ref_XP_001376592.1_	Monodelphis
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------MTIETVRADDITTL
NSIGEEEKKTPDRTMEHSTN
FTKL-------QQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSTIPQLTYDG
-H------PATSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NGKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRNYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGSWAPMRSKKE--------
--------------------
--------------------
----VQEVSAS--YNGVD-G
-CLSSP-LDHQVSSHHQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PSAKRTCPSVSPA-
-SP--LNNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-ASSQM
FLDQLNAGGST-ALPT--TN
GSSSGSNSSLVSSNSL-REG
HGHAVANRTSTDTAS---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_149041923_gb_EDL95764.1_	Rattus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------MAD
SAEL-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSTIPQLTYDG
-H------PASSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NTKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRTYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGSWAPMRSKKE--------
--------------------
--------------------
----VQEVTAS--YNGVD-G
-CLSST-LEHQVASHNQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PPAKRTCPSLSPT-
-SP--LSNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-TSSQM
FLDQLSAGGST-SLPA--TN
GSSSGSNSSLVSSNSL-RES
HGHGVASRSSADTAS---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_3643105_gb_AAC36701.1_	Mus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------MAD
SAEL-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPPTLS
---------PSTIPQLTYDG
-H------PASSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NTKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRTYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADS-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGSWAPMRSKKE--------
--------------------
--------------------
----VQEVTAS--YNGVD-G
-CLSST-LEHQVASHNQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PPAKRTCPSLSPT-
-SP--LSNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-TSSQM
FLDQLSAGGST-SLPA--TN
GSSSGSNSSLVSSNSL-RES
HGHGVASRSSADTAS---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_149691828_ref_XP_001496490.1_	Equus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-------MVFPSNFAVLTFQ
NSHI-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSTIPQLTYDG
-H------PASSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NTKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRNYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGSWAPMRSKKE--------
--------------------
--------------------
----VQEVSAS--YNGVD-G
-CLTST-LEHQVASHHQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PSAKRTCPSLSPT-
-SP--LNNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-TSSQM
FLDQLSAGGST-SLPT--TN
GSSSGSNSSLVSSNSL-RES
HSHPVASRSSTDTAS---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_193787695_dbj_BAG52901.1_	Homo
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------MFTLQ
DSYV-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSTIPQLTYDG
-H------PASSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NTKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRNYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGTWAPMRSKKE--------
--------------------
--------------------
----VQEVSAS--YNGVD-G
-CLSST-LEHQVASHHQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PSAKRTCPSLSPT-
-SP--LNNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-TSSQM
FLDQLSAGGST-SLPT--TN
GSSSGSNSSLVSSNSL-RES
HSHTVTNRSSTDTAS---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_115494992_ref_NP_001068864.1_	Bos
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------MAD
SAEL-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSTIPQLTYDG
-H------PASSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NTKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRNYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGSWAPMRSKKE--------
--------------------
--------------------
----VQEVSAS--YNGVD-G
-CLSST-LEHQVASHHQ---
-SSNKSKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PSAKRTCPSLSPT-
-SP--LNNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-TSSQM
FLDQLSAGGST-SLPT--TN
GSSSGSNSSLVSSNSL-RES
HGHTVANRSSSDTAA---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_74000632_ref_XP_866551.1_	Canis
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------MAD
SAEL-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSTIPQLTYDG
-H------PASSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQIILTVFSRDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NTKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRNYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGSWAPMRSKKE--------
--------------------
--------------------
----VQEVSAS--YNGVD-G
-CLSST-LEHQVASHHQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PSAKRTCPSLSPT-
-SP--LNNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-TSSQM
FLDQLSAGGST-SLPT--TN
GSSSGSNSSLVSSNSL-RES
HSHTVANRSSTDTAS---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>gi_114657766_ref_XP_523109.2_	Pan
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--MQKRSADRREMGLRPASL
SLRPFPGGAGRARMGGRETE
GAVTVKPRRLAPLFKWNVPV
SQLYVPGAGLRAPRAGRRPE
AGWEGGGADRGGARPARGAG
LAAAPGEVHCACADRRKMAD
SAEL-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSTIPQLTYDG
-H------PASSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NTKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRNYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGTWAPMRSKKE--------
--------------------
--------------------
----VQEVSAS--YNGVD-G
-CLSST-LEHQVASHHQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PSAKRTCPSLSPT-
-SP--LNNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-TSSQM
FLDQLSAGGST-SLPT--TN
GSSSGSNSSLVSSNSL-RES
HSHTVTNRSSTDTAS---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
>NP_057250.1
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------MAD
SAEL-------KQMVMSLR-
--VSELQVLLGYAGRNKHGR
KHELLTKALHLLKAG-CSPA
VQMKIKELYRRRFPQKIMTP
ADLSIPNVHSSP--MPATLS
---------PSTIPQLTYDG
-H------PASSPLL-PVS-
-------LLGP-KHEL-ELP
H---LTSALHPVHPDIKLQK
LPFYDLLDELIKPTSLASDN
S-----QRFRETCFAFALTP
QQVQQISS---SMDIS-GTK
CDFTVQVQLRFCLSETSCPQ
--------------------
--------EDHFPPNLCVKV
NTKPCSLPGYLPPTKNGVEP
KRPSRPINITSLVR--LSTT
VPNTIVVSWTAEIGRNYS--
MAVYLVKQLSSTVLLQRLRA
--KGIRNPDHSRALIKEKLT
ADP-----------------
-------DSEIATTSLRVSL
LCPLGKMRLTIPCRALTCSH
LQCFDATLYIQMNEKKPTWV
CPVCDKKAPYEHLIID--GL
FMEILKYCT--DCDEIQFKE
DGTWAPMRSKKE--------
--------------------
--------------------
----VQEVSAS--YNGVD-G
-CLSST-LEHQVASHHQ---
-SSNKNKKVEVIDLTIDSSS
--------------------
--------------------
--------D---EEEEE---
------PSAKRTCPSLSPT-
-SP--LNNKG----------
----ILS----------LPH
QASP----------------
--------------------
-VSRTPSLPAVDTSYI--NT
SLIQDYRHPFH----MTP--
-MPYDLQ-------------
--------GLDFFPFLSGDN
-QHYNTSLLAAAAAAVS--D
DQDL-LHSSRFFPY-TSSQM
FLDQLSAGGST-SLPT--TN
GSSSGSNSSLVSSNSL-RES
HSHTVTNRSSTDTAS---IF
GIIPDIISLD----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------
