>gi_148236424_ref_NP_001084194.1_	Xenopus
--------------------
--------------------
--------------------
--------------------
--------------------
---------------MESAD
STGK----------------
--------------------
--------------------
--------------GSTEQS
ES------------------
--------------------
--------------------
--------------------
-------------------Q
RQSQMDRLDREEAFYQFVN-
------NLN-----------
----DEDYRLMRDNNL----
-LGT--------------PG
EITKEELLQRLQQIKEG---
--------------------
--------------------
------PPQPST-EE---TR
GDSVS-------TGEDPAE-
----DSSNGDSIIDWLNSVR
QTGNTTRSGQRGNQ-S----
-WRAVSRTNPNSGDFRFSLE
INVNRT--------------
-----------SGTPSMPSL
DQS------------AEMPG
AEDMEVS--SQGEAENVPEP
EAVPESIPEPIP--------
------------------EP
ESVPE--------PESVPEP
ESVPEPESVPEPESVPEPVS
V-AEPEPESVAAS-------
-VP-----------------
--------------------
-------------------V
PEPESIAEPESVPESESIAE
PESV----------PEPESV
PEP-------ES----VPEP
ESVPEPE-------------
-------SVPEPES------
----VPEPESVPEPVSVAEP
EPE--------------SVA
ASVPVPEPESIAEPESVPES
ESIA---------EPESVPE
P---ESVPEPESVPEPESIA
E-PESV----PEPESVPVPE
SVPESVPVATRPAPVEVTVE
EAPIQRGQRRARSRSPDQRR
TRARTDRSRS----------
--------------------
---------PLYQTVD----
--------------------
------------------PP
IRRAQHSSSQ----------
--------------------
--------------------
TVDASNTEEAEGSSR-----
--------------------
--------------------
-----TRHHVSSQVH-----
-------SSS----------
--------------------
--------------------
--------------------
-----------------SNE
TEGSSRTRQHI---------
--TAR--QQAL----GTEGQ
SQ------------------
--------------------
--------------STVHLS
N-PESRSSSQT-------PQ
TDSPSNAETTGTGQRPPTIV
LDLQVRRVRP----------
--------------------
--------------------
--------------GDYRQR
DSIANRTRSRSQTPN--NTV
TYESERGG------------
FRRTFSRSERAGVR------
--TYVSTIRIPIRRILNT--
---GLSETTSVAIQTMLRQI
MTGFG--ELSYFMYNDND--
--ADPNNPTAVSPPAAVPG-
-----------E--------
------VQNNP------SAE
VRAPIAEPAEPVAPVESDEG
SNV-----------------
--------------ATSATR
REG-----------------
-RNSRGGVTLEESGSLPFL-
SLAQFFLLNEDDDDQPRG--
---LTKEQID----NLSTRN
YG------------------
-ENDALKTCSVCITE-----
----------YTEG---NKL
RKLPCSHE-------YHIHC
IDRWLSENST----------
-------CPICRRAVLVAGN
RESIV---------------
--------------------
--------------------
---------------
>gi_161086926_ref_NP_067375.3_	Mus
--------------------
------MGWKILPVCLS---
--------------------
--------------------
-------------LLLPVVL
IQQVSSQDL------SSCAG
RCGE----------------
--------------------
--------------------
--------------GYSRDA
TCNCDYNCQHYMECCPDFKR
V-------------------
--------------------
--------------------
---CTTELSCKGRCFE-SFA
RGRECDCDSQCKQYGKCCA-
------DYDSFCEEVHNPTS
PSPKTAPPPPGASHTIKSTT
KRSP--------------KS
PKKKTKKVVESEEITEEHSV
SENQESSSSSSSSSSTIRKI
KSSKNSANRELQKNPKVKDN
KKNT--PKKKPNPEP---PA
VDEAG-------SGLDNGEF
KLTPPPPDPPTTPHSKVTTS
PKTTAAKPVTPKPSLA----
--------PNSETSKEASLA
SNKETTVETKETTATNKQSS
ASKKKTTSAKETRSAEKTSD
KDV------------EPTST
TPKNSAPTTTKKPVTTTKEP
VPTTPKEPEPT---------
------------------TP
KEPPPTTKKPE--PTTPKEP
EPTTPKEPEPTTPKEPEPTT
P-KEPEPTTPKEPPPTTKKP
EPTT----------------
--------------------
-------------------P
KEPEPTTPKEPEPTTTKEPE
PTTTKEPESTTRKEPEPTTP
KEP-------EPTTPKEPEP
TTPKEPEPTTPKE-------
---------PEPTTLKEPEP
TTPKEPEPTTPKEPEPTTPK
EPE--------------PTT
PKEPEPTTPKEPEPTTPKEP
E-PT---------TPKEPEP
TTPKEPEPTTPKEPEPTTPK
E-PEPTTPKEPEPTTLKEPE
PTTPKEPEPTTPKEPEPTTL
KEPEP-----TTPKEPEPTT
LKE-----------------
--------------------
---------PEPTTPK----
--------------------
------------------EP
EPTTTKEPES----------
--------------------
--------------------
TTRKEPEPTTPKEPE-----
-PTT----------------
--------------------
-----PKEPEPTTPK-EPEP
TTPKEPEPTT----------
--------------------
--------------------
--------------------
-----------------PKE
PEPTTPKEPEP---------
--TTP--KEPE--P-TTPKK
PE------------------
--------------------
--------------PTTPKE
PEPTTPKEPEPTTPKEPEPT
TP-KEPEPTTRKEPEPTTPK
EPEPTTPKEP----------
--------------------
--------------------
--------------EPTTPK
KPEPTTTSPKTTTLKATTLA
PKVTAPAE------------
EIQNKPEETTPASEDSDDS-
--KTTLKPQKPTKAPKPT--
----KKPTKAPKKPTSTKKP
KTPKT--RKPKTTPSPLK--
--TTSATPELNTTPLEVML-
-----------PT-TTIPKQ
TPNPETAEVNPDHEDADGGE
GEKPLIPGPPVLFPTAIPGT
DLL-----AGRLNQGININP
MLSDETNLCNGKPVDGLTTL
RNGTLVAFRGHYFWMLNPFR
PPSPPRRITEVWGIPSPID-
TVFTRCNCEGKTFFFKDSQ-
YWRFTNDVVDPGYPKQIVKG
FGGLTGKIVAALSIAKYKDR
PESVYFFKRGGNIQQ-----
----------YTYK--QEPM
KKCTGRRPAINYSVYGEAAQ
VRRRRFERAVGPFQTHTFRI
HYSVPMRVSYQDKGFLHNEV
KVSTMWRGFPNVVTSAITLP
NIRKPDGYDYYAFSK-----
---DQYYNIDVPTRTARAIT
TRSGQTLSKIWYNCP
>NP_002365.3
---------------MADER
KDEAKAPHWTSAPLTEASAH
SHPPEIKDQGGAGEGLVRSA
NGFPYREDEEGAFGEHGSQG
TYSNTKENGINGELTSADRE
TAEEVSARIVQVVTAEAVAV
LKGEQEKEAQHKDQTAALPL
AAEETANLPPSPPPSPASEQ
TVTVEEDLLTASKMEFHDQQ
ELTPSTAEPSDQKEKESEKQ
SKPGEDLKHAALVSQPETTK
TYPDKKDMQGTEEEKAPLAL
FGHTLVASLEDMKQKTEPSL
VVPGIDLPKEPPTPKEQKDW
FIEMPTEAKKDEWGLVAPIS
PG-PLTPMREKDVFDDIPK-
---W--EGKQFDSPMPSPFQ
GGSFTLPLDVMKNEIVTETS
PFAPAFLQPDDKKSLQQTSG
PATAKDSFKIEEPHEAKPDK
MAEAPPSEAMTLPKDAHIPV
VEEHVMGKVLEEEKEAINQE
TVQQRDTFTPSGQEPILTEK
ETELKLEEKTTISDKEAVPK
ESKPPKPADEEIGIIQTSTE
HTFSEQKDQEPTTDMLKQDS
FPVSLEQAVTDSAMTSKTLE
KAMTEPSALIEKSSIQELFE
MRVDDKDKIEGVGAATSAEL
DMPFYEDKSGMSKYFETSAL
KEEATKSIEPGSDYYELSDT
RESVHESIDTMSPMHKNGDK
EFQTGKE-----------SQ
PSPPAQEAGYSTLAQSYPSD
LPEEPSSPQERMFTIDPKVY
G-EKRDLHSKNKDDLTLSRS
LGLGGRSAIEQRSMSINLPM
SCLDSIALGFNFGRGHDLSP
LASDILTNTSGSMDEGDDYL
PATTPALEKAPCFPVESKEE
EQIEKVKATGEESTQAEISC
ESPFLAKDFYKNGTVMAPDL
PEMLDLAGTRSRL-------
-------ASVSADAEVARRK
SV---PSETVVEDSRTGLPP
VTD---ENHVIVKTDSQLED
LGYCVFNKYTVPLPSPVQDS
ENLSGESGTFYEGTDDKVRR
DLATDLSLIEVKLAAAGRVK
D-EFSV--DKEASAHISGDK
SGLSKEFDQEKKANDRLDTV
LEKSE---EHADSKEHAKKT
EEAGDEIETFGLGVTYEQAL
AKDLSIPTDASSEKAEKGLS
SVPEIAEVEPSKKVEQGLDF
AVQGQLDVKISDFGQMASGL
NIDDRRATELKLEATQDMTP
SSKAPQEADAFMGVESGHMK
EGTKVSETEVKEKVAKPDLV
HQEAVDKEESYESSGEHESL
TMESLKADEGKKETS-----
-PESSLIQDEIAVKLSVEIP
CPPAVSEADLATDERADVQM
EFIQGPKEESKETPDISITP
SDVAEPLHETIVSEPAEIQS
EEEEIEAQGEYDKLLFRSDT
LQITDLGVSGAREEFVETCP
SEHKGVIESVVTIEDDFITV
VQTTTDEGESGSHSVRFAAL
EQPEVERRPSPHDEEEFEVE
EAAEAQAEPKDGSP-EAPAS
PEREEVALSEYKTETYDDYK
DETTIDDSIMDADSLWVDTQ
DDDRSIMTEQLETIPKEEKA
EKEARRSSLEKHRKEKPFKT
GRGRISTPERKVAKKEPSTV
SRDEVRRKKAVYKKAELAKK
TEVQAHSPSRKFILKPAIKY
TRPTHLSCVKRKTTAAGGES
ALAPSVFKQAKDKVSDGVTK
SPEKRSSLPRPSSI----LP
PRRGVSGDRDENSFSLNSSI
SSSARRTTRSEPIRRAGKS-
--GTSTPTTPGSTAITPG--
----TPPSYSSRTPGTPGTP
SYP----RTPHTPGTPKSAI
LVPSEKKVAIIRTPPKSPAT
PKQLRLINQPLPDLKNVKSK
IGSTDNIKYQP---------
--------------------
--------------------
--------------------
--------------------
----KGGQVQIVTKKIDLS-
HVTSKCGSLKNIRHRPGGG-
RVKIESVKLD--FKEKAQAK
VGSL----------------
-DNAHHVPGGGNVKI-----
----------DSQKLNFREH
AKARVDHG-------AEIIT
QSPGRSSVASPRRLSNVS-S
SGSINL-LESPQLATLAEDV
TAALAKQGL-----------
--------------------
--------------------
---------------
>gi_126308585_ref_XP_001376136.1_	Monodelphis
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---------MPTEWGMTKQI
LCMC----------------
--------------------
--------------------
--------------------
--------------IKEYDY
TVRSPECEEGREEWEDSQK-
-----------------LMK
KGK-AEEAGIGDTPNLEDQA
------------------AG
DVSQEELRVSAECQREESEI
LDFSANEIKSQMPQVSVEE-
--------------TFQKPQ
T-----PLRKK--EP-----
--------------------
----EMTVPLASQDNSVSSE
APSLEEDMKETCPALR----
-QINGDRTEQSLPSLKPSVL
ESSKPS--------------
--------GYDHFRVGVEGH
EVY------------GSFLS
EPGHYGAEAIGQDAINMPG-
ERISHMSAESIQSR------
------------------SP
GDSP------------LVLP
VKERAGVREDDEDRDIDESS
L-QDSPLSSQP---------
--------------------
--------------------
-------------------S
PRTESLQPQEVSSPSVASKE
TV------------AISGLP
VEH-------HIKIPLPDDF
LPKIPSEM------------
-----------PATE-----
--SKPPELSQLGTEGSDELS
SFE-----------------
--SSESVFQVEIKANIPKEQ
E------------FSELGPE
DTVSPEDTMSGEPGSPSASV
E-KD---AKIPEKHSLRSPS
GK------------------
--------------------
--------------------
--------------------
---------PVSRVPQ----
--------------------
------------------LK
ARKS--SVAG----------
--------------------
--------------------
SDEKKVKPSTPSSAQTFLKG
RPTI----------------
-----------------S--
-----PKRPSPVSSD-----
-PSITPSSPA----------
--------------------
--------------------
--------------------
-----------------VSS
VPGSSPKHISS---------
--VISHTGSSG----TKAMK
SK------------------
--------------------
--------------------
----RAESKSGIKMATHRAV
PSGHKGSANATRIPAKAS--
--GP----------------
--------------------
--------------------
--------------------
--------------------
--KTPPSA------------
-----GESTKSGERS-----
--GYSSPGSPGTPGS-----
---RSRTPSLPTPPT--REP
K------KVAVVRTPPKS--
--PSSTKSRLQTSAVPM---
-----------PDLKNVRSK
IGSTENLKHQP-------GG
GK------------------
--------------------
-----VQIFNKKLDLSNVQS
KCGSKDNIK-----------
-HVPGGGSVQIVYKPVDLS-
KVTSKCGSLGNIHHKPGGG-
QVEVKSEKLD--FKEKVQSK
IGSL----------------
-DNITHVPGGGNKKI-----
----------ESHKLTFREN
AKAKTDHG-------AEIVY
KSPTMSGDTSPRHLSNVS-S
TGSINM-VDSPQLATLADEV
SASLAKQGL-----------
--------------------
--------------------
---------------
>NP_001116538.1
--------------------
--------------------
--------------------
--------------------
-------------MAEPRQE
F--------------EVMED
HAGT-------------YGL
GD------------------
--------------------
---------RKDQGGYTMHQ
DQEGDTDAG--LKESPLQTP
T-------------------
--------------------
--------------------
--------------EDGSEE
PGSET---------------
------SDAKSTPTAEDVTA
PL--VDEGAPGKQAAAQPHT
-EIP--------------EG
TTAEEAGIGDTPSLEDEAAG
HVTQEPESGKVVQEGFLRE-
--------------------
------PGPP--------GL
SHQLM-------SGMPGAP-
----LLPEGPREA----TRQ
PSGTGPEDTEGGRH------
----------APELLKHQLL
GDLHQE--------------
-----GPPLKGAGGKERPGS
K--------------EEVDE
DRDVDES-----------SP
QDSPPSKASPA---------
------------------QD
GRPPQT-------AAREATS
IPGF----------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------PAEGAI
PLP-------VDFLSKVSTE
IPASEPD-------------
--------------------
------GPSVGRAKGQDAPL
EFT-----------------
-------FHVEITPNVQKEQ
--AH---------SEEHL--
----------GRAAFPGAPG
EGPEARGPSLG--------E
DTKEADLPE-----------
------------PSEKQPAA
APRGK---------------
--------------------
---------PVSRVPQ----
--------------------
------------------LK
ARMVSKSKDG----------
--------------------
--------------------
TGSDDKKAKTSTRSS-----
-AKT----------------
-----------------LKN
RPCLSPKHPTPGSSD-----
-PLIQPSSPA----------
--------------------
--------------------
--------------------
-----------------VCP
EPPSSPKHVSS---------
--VTS--RTG-----SSGAK
EM------------------
--------------------
--------------KLKGAD
G-KTKIATPRG-------AA
PPGQKGQANATRIPAKT---
--------------------
--------------------
--------------------
---------------PPAPK
TPPSSAT----------KQV
QRRPPPAG------------
PRSERGEPPKSGDRS-----
--GYSSPGSPGTPGS-----
---RSRTPSLPTPPT--REP
K------KVAVVRTPPKS--
--PSSAKSRLQTAPVPM---
-----------PDLKNVKSK
IGSTENLKHQP-------GG
GK------------------
--------------------
-----VQIINKKLDLSNVQS
KCGSKDNIK-----------
-HVPGGGSVQIVYKPVDLS-
KVTSKCGSLGNIHHKPGGG-
QVEVKSEKLD--FKDRVQSK
IGSL----------------
-DNITHVPGGGNKKI-----
----------ETHKLTFREN
AKAKTDHG-------AEIVY
KSPVVSGDTSPRHLSNVS-S
TGSIDM-VDSPQLATLADEV
SASLAKQGL-----------
--------------------
--------------------
---------------
>gi_189536984_ref_XP_001920675.1_	Danio
--------------------
--------MSSLSNQQP---
--------------------
--------------------
--------------ASPFPD
YSELCK--------------
--------------------
--------------------
--------------------
--------------------
-----------VPSMPTSAP
P-------------------
--------------------
--------------------
---PAWDWQHGDLSAKPNFS
VRAPGMTDEDKLCFYETPS-
------DLGQRNIPPSVSFG
STG-DSPESLSSSSAASPGK
-FTP----------------
----------LKCMEDNAGM
MLLDGVQTPVA---------
--------------------
------PLEPPNYCVIGVIN
DSYLE-------SRDEEEKC
DES-DEEVDLQPCFMGRAEQ
QRKAMRRAMSECSHLS----
----VPASLELPDKYPGVLD
EFASPV-----IGASRRQHG
AAMKRSLTVADDQPPTPPPV
LSA----------------G
AARGDLR--NDLDLSCFSMS
KKQSSFPLSPVE--------
------------------DL
LEAPFIEKDQGVVLAVPVNA
FVAKNSEKNKPEVNKMDPVQ
KFDEFDIFSKTEK-------
--------------------
--------------------
-------------------D
QKMETITEKDKSEPKQTTKA
--------------------
----------ENTEPLDKNK
EVEKKTDETVHHV-------
-------ETPVKVEKIEKVE
RSTKDETEKAAMVEKSTDLI
EKT-----------------
-EKTAEFSSKKEEPVEKQEL
-------------KKEEVKV
ENKSEQKDDVKEKAEQKTQQ
D----------KTEEEKVEE
KAEKSEPADKKPAKAETKDD
KAKKA----AAKPSAAKPAL
TNGA----------------
--------------------
---------PGKDLS-----
--------------------
------------------SP
EKKT--KPVA----------
--------------------
--------------GLSKPS
SAKPRPSSASTATAA-----
--------------------
--------------------
-----PKRPTATSASSGPAP
ISKKAPAPKT----------
--------------------
--------------------
--------------------
-----------------SAA
PAGT--KRPAT---------
--ATA--RPPTATTAARDVK
PK------------------
--------------------
--------------TLTEKR
------------------PL
VPKPSTAPSRPAADKPAST-
-----TRPTA----------
--------------------
--------------------
--------------SAPAAR
RPLAAKAESKPADDK--KAS
TLKTTVTD------------
GARSKPATARPSTSGTISSS
ASTRPRPTKTPLAGGTGTTP
EVPRIQTMPRPPRQSIFSTS
TTNTT--RSTARTTTTTSTT
RITSSSTASTARPSSTAA--
-----------PDVKNIRSK
IGSTDNIKHQP-------GG
GK------------------
--------------------
-----VQIVSKKVDYSHVTS
RLGSKDNMK-----------
-HIPGGGNVQILSKKIDLS-
KVTSKCGSKSNIKHKPGGG-
EVKIESHKVN--YKDKAQSK
VGSM----------------
-DNVNHEPGGGKIKVCTNVQ
LNLQRHYRINESMVFELTPD
SQCLGIEE----SVAEGVQE
TPCSGVSAAADAQENGLKDG
GPCKS--DPIRDSQGLDLLI
PETSK---FIESFKLNFREN
ARSRTDHGADIIEWPVSDEN
PVQQQLLRSSVSLNDSLSST
AGIPRSHTTPNLEHT
>gi_118085434_ref_XP_418480.2_	Gallus
--------------------
----MADLDHNLSLADA---
--------------------
--------------------
-------------LTEPPPE
IEEEVKRDFIATLEAEKFDD
VVGETVDKTDY------VPL
LD------------------
--------------------
----------DDDAGSQEPK
SKGHADSIQ--VEHPSATGP
T-------------------
--------------------
--------------------
---V---IANGDHGMED-HR
PVFPGEIMDEKLSYKEFLDR
NDTWAMDDRELCFEP--VFK
PMEMADPFSMHRGENLPDLS
--FP--------------PD
MKNVQFFTDHADTSRDIH--
----VPHGSVMVPEQPFLG-
--SPYCPAEVLDPSAFVGLD
SAAE--FLQDKA-VP-----
EDHWM-------GAQHYAKG
SDA-SFFAEPPVPPAAPGAE
VLTVPECPAAAAPYFV----
-PTALA---ASPAEAKAAEA
PKADAE-----SAVASDATS
VSAEQAGPI--LAGDTKPPH
AVD------------AESAP
PAEDEPP--QGTDVGFAPAA
EAKPPSG-------------
------------------AA
ASSPVLDAAWS--PAADTEP
HCAVGLEFAPAADSNPHHAA
D-LTFAPTADAESHRAADSE
FTF-----------------
--------------------
-------------------P
AEVAHLRAVDSSPAPAADAK
PSP-----------ADSGFA
SAP-------EAKAVCAADT
EVAAVEEL------------
-------VTSEPSAQHDKTP
SHEAPAETAASMEQEPKAPE
GYV--------------AVS
LEKPSASHHAEHLPAPTNHL
PEPA---------VPVETKE
DTVLENKE----------LL
S-EQRV-AAVDVPAVEQRKE
ETEQNHIQHTEPLQGAPLQE
PA--------AKPEEPKAAD
AVTGNDITAP----------
--------------------
---------PNKELPP----
--------------------
------------------SP
EKKT--KPAA----------
--------------------
--------------------
STPSAKPTATKARPA-----
-AAT----------------
-----------------S--
-----PKRPASAT-P-G---
-THKKPTSPT----------
--------------------
--------------------
--------------------
-----------------AGP
PATTTPKRPAS---------
--SAT--RPST-LT-PKEIK
PK------------------
--------------------
---------------VSSLS
L-PEKRSSLGNLFSASPPSV
X---KPSSSYPTXTSPVSVX
NHSPLSYQYX----------
--------------------
--------------------
--------------PRIL--
HWAAIKTDAKPADAK--KTT
A-KSPSAD------------
LARPKSAAG-STVKSSATTS
TTTTTTTSTTAVPSAATS--
---RPKPKPAATKPT--TTT
STTAADAKKPPAKAAT-K--
--P-SAAPKPLRPTSSAAA-
-----------PDLKNVRSK
IGSTDNIKHQP-------GG
GKGKVEKKPESAAAARKSEP
NVVPKMAPTKTAVTKEGVPK
QPNGKVQIVSKKANYSHVQS
KCGSKDNIK-----------
-HVPGGGNVQIQNKKVDLS-
KVSSKCGSKANIKHKPGGG-
DVKIENQKLN--FKEKAQAK
VGSL----------------
-DNVGHSPAGGTVKA-----
----------EGSA---EPG
QLPPAPQN-------GEV--
---RAEQAGSALQENGVGPA
VPTALSGGDQREIQSFETQI
QETN----------------
--------------------
--------------------
---------------
>gi_149018456_gb_EDL77097.1_	Rattus
--------------------
--------MADLSLVDA---
--------------------
--------------------
-------------LTEPPPE
IEGEIKRDFMAALEAEPYDD
IVGETVEKTEF------IPL
LD------------------
--------------------
---------GDEKSGNSESK
RKPCVDTSQ--VEDIPSSKP
T-------------------
--------------------
--------------------
---L---LANGDHGVEGNNT
TGSPTDFLVENVDYEDYQN-
SQSWP-EDASFCFQPQQVLD
TNQ-ADPFNVHHDDGLADLL
-FVS--------------SG
PTNASAFIEENNPLEDSYGV
LPCDSFAPTAVVSQEWSVG-
--APDSP----HSEPCVSPE
VTIE--TAQPAT-EL---SK
AVDLE-------SVKEQLPA
KAL-EMMAG-QTTDAVPSKE
SEGSPDTDAAPGPD-T----
-DVTLTKDIEESSSPDVISA
NVTQPF-TESDMFLTQEMEL
LIGTEAAQVKDTMSSVEPDI
SSA------------KNTAP
PTEEETV--PGKDMTFPKEA
ETALPIEMDLAP--------
------------------PE
DVALPKETELELAPAAGTAP
LSETEVALAKDEEPSTGIPA
A-QEMLLSSETEV-------
-VL-----------------
--------------------
-------------------P
SDSIMTLTKEVTVPLEAAGP
LVSDMTAILETEMTLGGGTA
TPT-------ETKLGKVKDM
APLPESEVALGKDVVTLPET
KVTEFNNVTPLSEEEVASIK
DVSPSPETETAKNAD--LHS
GTE--------LTLDNSMTP
PSDPALPLETKVATVQIKDK
ETVQ---------TQEELSE
DSQLESVQLEGQSAVPPCTI
S-PEPV-KAADQKSTLPVDE
GSPLEKLEQKETSGSQPPEL
CS------GVSRQEEGKAAV
GLTGNDIATP----------
--------------------
---------PNKELPP----
--------------------
------------------SP
EKKA--KPLA----------
--------------------
--------------------
TTQPAKTSTSKAKIQ-----
-PTS----------------
-----------------L--
-----PKQPAPTTSG-G---
-LNKKPMSLA----------
--------------------
--------------------
--------------------
-----------------SGS
VPAAPHKRPAA---------
--ATATARPST-LP-ARDLK
PK------------------
--------------------
--------------PITETK
V-AEKRTSPSK--PSSAPAL
RPGPKTTPTISKATSPSTLV
STGS-SSRSP----------
--------------------
--------------------
--------------STTLPK
RPTTTKTEGKPADVK--RMT
A-KSATAD------------
LSRSKTTSA-SSVKR-----
--NTTPTGATPPAGMAST--
---RVKPMSAPCRSS--VAL
SVD----KKP---TST-K--
--PSSSAPRVSRLATTVSA-
-----------PDLKSVRSK
VGSTENMKHQP-------GG
GRAKVEKKTEAATTAGNPEP
NAV-----TKAASSISSAPK
PPAGKVQIVSKKVSYSHIQS
KCGSKDNIK-----------
-HVPGGGNVQIQNKKVDIS-
KVSSKCGSKANIKHKPGGG-
DVKIESQKLN--FKEKAQAK
VGSL----------------
-DNVGHLPAGGTVKT-----
----------EGGG---SEA
PPCPGPPA-------GEEPA
IPEAAPDAGAPTSASGLS-G
HTTLSGGGDQREPQTLDSQI
QETSI---------------
--------------------
--------------------
---------------
>gi_62088334_dbj_BAD92614.1_	Homo
PHGSSRRSPGSLLPQLRLGG
GGQLQWCRMADLSLADA---
--------------------
--------------------
-------------LTEPSPD
IEGEIKRDFIATLEAEAFDD
VVGETVGKTDY------IPL
LD------------------
--------------------
---------VDEKTGNSESK
KKPCSETSQ--IEDTPSSKP
T-------------------
--------------------
--------------------
---L---LANGGHGVEGSDT
TGSPTEFLEEKMAYQEYPN-
SQNWP-EDTNFCFQPEQVVD
PIQ-TDPFKMYHDDDLADLV
-FPS--------------SA
TADTSIFAGQNDPLKDSYGM
SPCNT----AVVPQGWSVE-
--ALNSP----HSESFVSPE
AVAE--PPQPTA-VPLELAK
EIEMA-------S-EERPPA
QAL-EIMMGLKTTDMAPSKE
TEMALAKDMALATK-T----
-EVALAKDMESPTKLDVTLA
KDMQPS-MESDMALVKDMEL
PTEKEVALVKDVRWPTETDV
SSA------------KNVVL
PTETEVA--PAKDVTLLKET
ERASPIKMDLAPSKDMGPPK
ENKKETERASPIKMDLAPSK
DMGPPKENKIV--PAKDLVL
LSEIEVAQANDIISSTEISS
A-EKVALSSETEV--ALARD
MTL-----------------
--------------------
-------------------P
PETNVILTKDKALPLEAEVA
PVKDMAQLPETEIAPAKDVA
PST-------VKEVGLLKDM
SPLSETEMALGKD-------
-------VTPPPETEVVLIK
NVCLPPEMEVALTEDQVPAL
KTEAPLAKDGVLTLANNVTP
AKDVPPLSETEATPVPIKDM
EIAQ---------TQKGISE
DSHLESLQDVGQSAAPTFMI
S-PETV-TGTGKKCSLPAEE
DSVLEKLGERKPCNSQPSEL
SSETS---GIARPEEGRPVV
SGTGNDITTP----------
--------------------
---------PNKELPP----
--------------------
------------------SP
EKKT--KPLA----------
--------------------
--------------------
TTQPAKTSTSKAKTQ-----
-PTS----------------
-----------------L--
-----PKQPAPTTIG-G---
-LNKKPMSLA----------
--------------------
--------------------
--------------------
-----------------SGL
VPAAPPKRPAV---------
--ASA--RPSI-LP-SKDVK
PK------------------
--------------------
--------------PIADAK
A-PEKRASPSK--PASAPAS
RSGSKSTQTVAKTTTAAAVA
STGP-SSRSP----------
--------------------
--------------------
--------------STLLPK
KPTAIKTEGKPAEVK--KMT
A-KSVPAD------------
LSRPKSTST-SSMKK-----
--TTTLSGTAPAAGVVPS--
---RVKATPMPSRPS--TTP
FID----KKP---TSA-K--
--PSSTTPRLSRLATNTSA-
-----------PDLKNVRSK
VGSTENIKHQP-------GG
GRAKVEKKTEAAATTRKPES
NAV-----TKTAGPIASAQK
QPAGKVQIVSKKVSYSHIQS
KCGSKDNIK-----------
-HVPGGGNVQIQNKKVDIS-
KVSSKCGSKANIKHKPGGG-
DVKIESQKLN--FKEKAQAK
VGSL----------------
-DNVGHLPAGGAVKI-----
----------ETYRLTFRAN
ARARTDHG-------ADIVS
RPPHFP--------------
------GGPNSGSRVLGPLS
RAVH----------------
--------------------
--------------------
---------------
>NP_002366.2
--------------------
--------MADLSLADA---
--------------------
--------------------
-------------LTEPSPD
IEGEIKRDFIATLEAEAFDD
VVGETVGKTDY------IPL
LD------------------
--------------------
---------VDEKTGNSESK
KKPCSETSQ--IEDTPSSKP
T-------------------
--------------------
--------------------
---L---LANGGHGVEGSDT
TGSPTEFLEEKMAYQEYPN-
SQNWP-EDTNFCFQPEQVVD
PIQ-TDPFKMYHDDDLADLV
-FPS--------------SA
TADTSIFAGQNDPLKDSYGM
SPCNT----AVVPQGWSVE-
--ALNSP----HSESFVSPE
AVAE--PPQPTA-VPLELAK
EIEMA-------S-EERPPA
QAL-EIMMGLKTTDMAPSKE
TEMALAKDMALATK-T----
-EVALAKDMESPTKLDVTLA
KDMQPS-MESDMALVKDMEL
PTEKEVALVKDVRWPTETDV
SSA------------KNVVL
PTETEVA--PAKDVTLLKET
ERASPIKMDLAPSKDMGPPK
ENKKETERASPIKMDLAPSK
DMGPPKENKIV--PAKDLVL
LSEIEVAQANDIISSTEISS
A-EKVALSSETEV--ALARD
MTL-----------------
--------------------
-------------------P
PETNVILTKDKALPLEAEVA
PVKDMAQLPETEIAPAKDVA
PST-------VKEVGLLKDM
SPLSETEMALGKD-------
-------VTPPPETEVVLIK
NVCLPPEMEVALTEDQVPAL
KTEAPLAKDGVLTLANNVTP
AKDVPPLSETEATPVPIKDM
EIAQ---------TQKGISE
DSHLESLQDVGQSAAPTFMI
S-PETV-TGTGKKCSLPAEE
DSVLEKLGERKPCNSQPSEL
SSETS---GIARPEEGRPVV
SGTGNDITTP----------
--------------------
---------PNKELPP----
--------------------
------------------SP
EKKT--KPLA----------
--------------------
--------------------
TTQPAKTSTSKAKTQ-----
-PTS----------------
-----------------L--
-----PKQPAPTTIG-G---
-LNKKPMSLA----------
--------------------
--------------------
--------------------
-----------------SGL
VPAAPPKRPAV---------
--ASA--RPSI-LP-SKDVK
PK------------------
--------------------
--------------PIADAK
A-PEKRASPSK--PASAPAS
RSGSKSTQTVAKTTTAAAVA
STGP-SSRSP----------
--------------------
--------------------
--------------STLLPK
KPTAIKTEGKPAEVK--KMT
A-KSVPAD------------
LSRPKSTST-SSMKK-----
--TTTLSGTAPAAGVVPS--
---RVKATPMPSRPS--TTP
FID----KKP---TSA-K--
--PSSTTPRLSRLATNTSA-
-----------PDLKNVRSK
VGSTENIKHQP-------GG
GRAKVEKKTEAAATTRKPES
NAV-----TKTAGPIASAQK
QPAGKVQIVSKKVSYSHIQS
KCGSKDNIK-----------
-HVPGGGNVQIQNKKVDIS-
KVSSKCGSKANIKHKPGGG-
DVKIESQKLN--FKEKAQAK
VGSL----------------
-DNVGHLPAGGAVKT-----
----------EGGG---SEA
PLCPGPPA-------GEEPA
ISEAAPEAGAPTSASGLN-G
HPTLSGGGDQREAQTLDSQI
QETSI---------------
--------------------
--------------------
---------------
>gi_27806553_ref_NP_776530.1_	Bos
--------------------
--------MADLSLADA---
--------------------
--------------------
-------------LTEPSPE
IEEEIKRDFIATLEAEAFDD
VVGETVGKTDY------IPL
LD------------------
--------------------
---------VDEKTGSSESK
KKPCSDTSQ--VEGTPSSQA
A-------------------
--------------------
--------------------
---V---LANGDHGIERNDV
TGFPSEFLEEKMAYQGYQN-
SQNWP-ENTNFCFEPEHMVN
PIQ-TDPFKMHHDDGLEDSL
-FFP--------------SG
TTNTSVFVEQNDPLKDTYGM
LPCDTFAPAAVVPQGWSAE-
--APNLA----HLESFTSPE
AVPQ--PLQPTA-EP---AE
KVEMA-------SGEERA--
EAL-EMMMKLQAADMAPSRE
AEMVLAKDVVPATE-T----
-GVALAKDMESPTKPDEALV
KDVESS-IESDMALVKDVVL
PVQTEETAVKDAILPTETDV
SLD------------EDLAL
STETEVS--TAQDILLFKET
ESIPPVTMDLAS--------
------------------AE
GTVPPTDQEMT--PVKVAAS
LSEIEAPLDEDIVSSTEIRS
A-KEIGLSSETEV--ALSRE
MGL-----------------
--------------------
-------------------P
PETEAILDKDMAAPPETEVI
V-------------PVKDMA
PSP-------GIETTLAKDV
APRQEIEVTLGKD-------
-------TVSLPATEMALGR
NVALPPETEVTLAKDVAQPP
ETE--------VNLANNAAL
AK----FSEAEVVPVPVKDM
ETAQ---------TQEATSE
DSQLKSLQDEGQSAVP-LMT
S-PEAV-VAMGQKHSLPTDE
DSVLEELEQKKP-SSQTSEL
PSETS---GVAKPEEGPPTG
SVSGNDITAP----------
--------------------
---------PNKELPP----
--------------------
------------------SP
EKKT--KPLA----------
--------------------
--------------------
TTQPAKTSTSKAKTQ-----
-PTS----------------
-----------------L--
-----PKQTAPTTLG-G---
-SNKKPMSLA----------
--------------------
--------------------
--------------------
-----------------SGS
VPAAPPKRPAA---------
--ATS--RPST-LP-SKDTK
PK------------------
--------------------
--------------PVAEAK
I-PEKRVSPSK--PASAPAV
KPGSKSTQAVPKAPATATLA
SPGS-TSRNL----------
--------------------
--------------------
--------------STPLPK
RPTAIKTEGKPAEIK--KMA
T-KSAPAD------------
LSRPKSTTT-SSVKK-----
--STTVPGTAPPAG-APS--
---RARPTATPPRPS--GTP
PVD----KKP---TAA-K--
--PTSSAPRLGRVAANASA-
-----------PDLKNVRSK
VGSTENIKHQP-------GG
GRAKVEKKTEAAAPARKPEP
NAV-----TKAAGPIGNA--
--------------------
--------------------
-QKPPTGKVQIQNKKVDIS-
KVSSKCGSKANIKHKPGGG-
DVKIESQKLN--FKEKAQAK
VGSL----------------
-DNVGHLPAGGAVKT-----
----------EGGG---SEA
PPCPGPPA-------GEELA
IPEAAPEAGAPASASGLS-G
HTTLAGGGDQREAQTLDSQI
QETSKWLGLA----------
--------------------
--------------------
---------------
>gi_194221363_ref_XP_001495345.2_	Equus
--------------------
--------MADLSLADA---
--------------------
--------------------
-------------LTDPPPE
IEEEIKRDFIATLEAEAFDD
VVGETVGKTDY------IPL
LD------------------
--------------------
---------VDEKTGNSESK
KKPCSDASQ--VEGTPSSKP
A-------------------
--------------------
--------------------
---V---LANGDHGIEGNDT
IGSPTEFLEENMAYQGYQN-
---WP-ENTNFCFQPEQVVN
PIQ-TDPFKMHHDDGLEELL
-FLP--------------SG
TTSASAFVEQNNPLEDSYGL
FPCDTFAPTAVVPQGWSVE-
--APNSP----QLESFISAE
AITQ--PTQPTA-EP---AK
DVEMA-------SAEERAPM
KAL-EMM-GLKTADMASSRE
KEMTSAKDEAPAAE-T----
-EVALAKNMESPTKSHASLA
KDMESS-TESDMALVKDMVP
PKETEEAPVKNVLSPTETGV
SFT------------KDMVL
PTETEVA--LAKDVVVFKET
ERASPIKMDLAP--------
------------------AE
GIVPPTDREMA--QANVVES
LSEIQMALAKDIASSTEKSS
A-EEVGLSSETEV--ALTRD
ITL-----------------
--------------------
-------------------P
LETKVVLSKDVALPPETEVA
--------------PVKDMA
QPP-------ETEVALVKDV
APPAETEMALGKD-------
-------VALSPETEVARVK
DVLLPPETEVALAKDVAVPP
GPE--------VTLTNNVTP
AKDVAP--PSEVAPVPVKDM
EIAR---------TQEEINE
DSQLESLQDEGQSAAPASMI
S-PEPV-TATGQKYSLPADE
DSLSEKLDQKKPVSSQPSEL
SSETS---GIAKPEEVRPTV
SVTGNDITAP----------
--------------------
---------PNKELPP----
--------------------
------------------SP
EKKT--KPLA----------
--------------------
--------------------
TTQPAKTSTSKAKTQ-----
-PTS----------------
-----------------L--
-----PKQPAPTTFG-G---
-SNKKPMSLA----------
--------------------
--------------------
--------------------
-----------------SGL
VAAAPPKRPAA---------
--ATT--RPSSILP-SKDAK
PK------------------
--------------------
--------------PVAEAK
I-PEKRASPSK--PASAPAS
RPGSKSTQTVPKATAAATVA
SAGP-SSRSP----------
--------------------
--------------------
--------------PAPLPK
KPTAIKTEGKPADIK--KMA
T-KSAPAD------------
LSRSKSTST-SSMKK-----
--NTTVPGAAPPAGVAPS--
---RVKPTPTPSRPS--GTP
SLD----KKP---TSA-K--
--PSSSAPRLSRPATNASA-
-----------PDLKNVRSK
VGSTENIKHQP-------GG
GRAKVEKKTEAVATARKPEP
NAV-----TKTAGPIASAQK
PPAGKVQIVSKKVSYSHIQS
KCGSKDNIK-----------
-HVPGGGNVQIQNKKVDIS-
KVSSKCGSKTNIKHKPGGG-
DVKIESQKLN--FKEKAQAK
VGSL----------------
-DNVGHLPAGGAVKT-----
----------EGGG---SEA
PPCPGPPA-------GEELA
IPEAAPEAGAPTSASGLS-G
HTILSGGGDQREAQTLDSQI
QETSKWLGLIETYRLTFRAN
ARARTDHGADIVSRP-----
---PHFPGGPGSGTRALGFL
SQAAL----------
>gi_73985682_ref_XP_541897.2_	Canis
--------------------
--------MADLSLADA---
--------------------
--------------------
-------------LTEPPPE
IEEEIKRDFIATLEAEAFDD
VVGETVGKTDY------IPL
LD------------------
--------------------
---------VDEKTGNSDSK
KKPCSDPSQ--VEGAPS-KP
T-------------------
--------------------
--------------------
---G---LANGDHGIEGNDT
AGSPTQFLEEKMPYEGYQN-
IQSWP-ENTNFCFEPEQLVN
PTQ-TDPFKMHHDDGLEDFL
-FLP--------------SG
TTSAAAFTERNDPLQDSYGL
FPCGTFSPAAVVPQGWPME-
--APNSP----HSESFISPM
ATPQ--PLQPT--EP---AE
EVEMT-------SAEERAPA
EAL-ETMRGLEAADMSPFRE
TEMALAEDLAPATE-I----
-EVALAKDMEVSPKSDVTQA
KDIESS-MESDMALVKDMVL
PRETEEAPVKDVVLSREEDV
SLA------------KDVVL
PPETEVA--LAKDILSFKET
ERAPPIKMDLSP--------
------------------DE
GTVPCTDREMA--PAKGVVS
LSEIEVALAKDVISSTEIPS
A-KEVALSPETEV--APTGD
MAL-----------------
--------------------
-------------------P
PETKVILTEVVPLPPETKVA
AVKDIALYPDIEKTPVKDVA
PSP-------ESEMVLGKDV
SPSQETELALGKDMVSPPET
EVALDKNVAVPPETEVTLTK
DVPQPPETEVALTKDVALPP
GTE--------VILANNVNP
AKDVAPLSETEVAPVPAKDM
DTPW---------TQEEISK
ASQLKSPKDEGQSAASTFII
S-PEPV-PAMGQKYNLPTDD
DSVLEKQKQKKPFSSQPPEL
SSEIS---GISKPEEGRPAG
SVTGNDITTP----------
--------------------
---------PNKELPP----
--------------------
------------------SP
EKKT--KPLA----------
--------------------
--------------------
TTQPAKTSTSKAKTQ-----
-PTP----------------
-----------------L--
-----PKQPAPTTLG-G---
-SNKKPMSLA----------
--------------------
--------------------
--------------------
-----------------SGL
VPAAPPKRPAA---------
--ATA--RPST-LP-SKDAK
PK------------------
--------------------
--------------PIAEAK
I-PEKRASPSK--PASVPAL
RPGSRGTQTVPKATAATSPA
SAGS-SSRSP----------
--------------------
--------------------
--------------PTPVPK
RPTAVKTEGKPADMK--KTA
T-KSVPAD------------
LSRTKTTTTTSSVKK-----
--NTTVPGAAPTAGVAPS--
---RAKPTPPPSRPS--GTP
SSD----KKP---MST-K--
--PSSSTPRLSRLSTNASA-
-----------PDLKNVRSK
VGSTENIKHQP-------GG
GRAKVEKKTEASAPARKPEP
NAV-----TKTAGPIASAQK
PPAGKVQIVSKKVSYSHIQS
KCGSKDNIK-----------
-HVPGGGNVQIQNKKVDIS-
KVSSKCGSKANIKHKPGGG-
DVKIESQKLN--FKEKAQAK
VGSL----------------
-DNVGHLPAGGAVKT-----
----------EGGG---SEA
PPCPGPPA-------GEEPA
IPEAAPEAGAPTSASGLS-S
HPTLAGGGDQREAQTLDSQI
QETSI---------------
--------------------
--------------------
---------------
