>gi_217035123_ref_NP_001074460.2_	Danio
--------------------
--------------------
------MASHFSGVLQLTDL
DDFITPSQECVKPVKVEKK-
QGRSVAKIQIEDDGSYF-QV
HQDGQRQKLEKAKITLNDCL
ACSGCITSAESVLITQQSHE
ELYRVLRH----NKQVSSTE
QKVVVVSVSPQSRASLAAHY
GIG-----------------
-----SSEVARKLTSFLKHL
GVHHVFDTAFSRS-----FS
LIESQREFLQRFSQRE----
ADKKALPMLASA--------
-----------CP---GWIC
YAEKT------------HGE
FILPYISTTRSPQQIMGSLV
KGYFASQKGVSPQMIYHVTV
MPCYDKKLEASRPDFYLS--
---EHETREVDCVITS----
--------------------
--------------------
--GEVLKMLEEEKVSLRDVQ
PAPLDTM-------------
-------------------F
SNVCGEELLGHAGSGSGGYL
HHIYKHAAKQLFGV------
-DVDELTYKTMKNKDFQEVT
LEKDGQ--------------
------------VLLKFAAV
YGFRNIQNLVQKLK------
-------------RGKSPYH
FVEVMACPSGCLNGGGQLKP
SADQSNKELLQQVEEVYRSE
HPSV-PEDDSQVAELYQSWL
ES-VGEEKARQLLHTQYHAV
EKTANG--LSIKW
>gi_47218040_emb_CAG11445.1_	Tetraodon
--------------------
--------------------
------MASHFSGVLQLTDL
DDFITPSQECVKPVKVEKK-
QGKSVAKIQIEEDGSYI-QI
NQDGGKQKLEKAKITLNDCL
ACSGCITSAESVLITQQSHE
ELFRVLQH----NKASET-E
KKVVVVSVSPQSRASIAARY
GLS-----------------
-----STEAGRRLTSFFKGL
GVHHVFDTTFTRT-----FS
LLESQREFVERFQRKE----
QDNKSLPMMTSA--------
-----------CPGTPGWIC
YAEKT------------HGD
LILPYISTTRSPQQMMGSLV
KGYFAEQQGLSPQQIYHVAV
MPCYDKKLEASRSDFHMN--
---EAQTREVDCVITS----
--------------------
--------------------
--GEVQLMLEEKNVSLSDVE
PAPLDTV-------------
-------------------F
SNVNGDEFLSHAGSSSGGYL
HHVFTYAAKHLFGE------
-EVKELTYKTLKNKDFQEVT
LEKDGV--------------
------------VLLCFAST
YGFRNIQNLVQKFK------
-------------RGKCPYH
FVEVMACPSGCLNGGGQLKA
LPGQNPKELLQKVEEIYRAE
RSMV-PEDNTRVAELYHSWL
HS-VGEERAKELLHTRYHTV
EKMKNG--LTMKW
>gi_224070248_ref_XP_002188515.1_	Taeniopygia
--------------------
--------------------
------MAARFSAALQLTEL
DDFIAPAQECIKPVKVQKN-
PTKAAARIRIEADGSYF-QV
NQDGEAEKLEKAKITLNDCL
ACSGCITSAETVLVRQQSHE
ELCKVLAL----NKAAAAHE
QKLVVVSVSPQSRASLAARC
KLG-----------------
-----LLETAQKLTTFLKGL
GVHHVFDTTFSRN-----FS
LLESQQEFVRRFHKQA----
EDKKALPMLASA--------
-----------CP---GWIC
YAEKT------------HGS
FIIPHISTTKSPQQVMGSLV
KGYFAEQQHLPPDRIYHVTV
MPCYDKKLEASRPDFFSQ--
---EYQTRDVDCVITT----
--------------------
--------------------
--GEVLKLLEQEGVSLSDLD
PAPLDTM-------------
-------------------L
GRAA-EELSSHRGGGSGGYL
EHIFRHAARELFGV------
-HVASIHYKPLRNKDFQEVT
LERDGE--------------
------------VLLQFALA
YGFRNIQNLVQKLK------
-------------RGKCPYH
YVEVMACPSGCLNGGGQIK-
LEGESSKEELQQVERLYESL
RAEI-PEENQAVRELYEHWL
GG-WGSDRALQVLHTQYHAV
ERASSA--LSIKW
>gi_73959191_ref_XP_547207.2_	Canis
--------------------
--------------------
------MASPFSGALQLTDL
DDFIGPSQDCIKPVKVDRR-
PGSGVAKIHIEDDGSYF-QV
SPDGGTQRLEKAKISLDDCL
ACSGCVTSAETVLITQQSHE
ELRKVLDA----NKTAAPGQ
QRLVVVSVSPQSRASLAARF
QLS-----------------
-----PTDTARKLTAFFKKI
GVHYVFDTAFSRN-----FS
LLESQREFVQRFREQT----
NSTQALPVLTSA--------
-----------CP---GWIC
YAEKT------------HGN
FLIPYLSTARSPQQVMGSLV
KDFFAQQQHLTPDRIYHVTV
MPCYDKKLEASRPDFFNQ--
---EHQTRDVDCVVTT----
--------------------
--------------------
--GEVFKLLEEEGVSLSELE
PAPLDSL-------------
-------------------C
SSMSAQEPSSHRGGGSGGYL
EHVFQHAARELFGI------
-HVDEVTYRPLRNKDFQEVT
LEKEGR--------------
------------VLLHFAAA
YGFRNIQNLVQKLK------
-------------RGRCPYH
YVEVMACPAGCLNGGGQLKA
PD-MPSKELLQQVEMLYGMV
RTEV-PENVPGVQELYRSWL
QG-EGSEQAGRLLHTSYHAV
EKASSS--LSIRW
>gi_152941142_gb_ABS45008.1_	Bos
--------------------
--------------------
------MASPFSGALQLTDL
DDFIAPSQDCIKPMKVDRR-
PGSGVAKIHIEDDGSYF-QV
SQDGGMKKLEKAKISLDDCL
ACSGCVTSAETVLITQQSHE
ELRKVLGA----NKTAAPDQ
QKLVVISVSPQSRASLAVRF
QLN-----------------
-----PTDTARKLTAFFKKI
GAHYVFDTAFSRN-----FS
LLESQREFVRRFRGQA----
DPEQALPVLTSA--------
-----------CP---GWIC
YAEKT------------HGS
TLLPHISTARSPQQVMGSLV
KDFFAQQQHLTPDKVYHATV
MPCYDKKLEASRPDFFSQ--
---EHQTRDVDCVITT----
--------------------
--------------------
--GEVFKLLEEGGVSLSELE
PAPLDSL-------------
-------------------C
SSASAQEPTSHQGGGSGGYL
EHVFRHAAQELFGI------
-HVTEVTYRPLRNKDLQEVI
LEREGQ--------------
------------VLLHFAAA
YGFRNIQNLVQKLK------
-------------RGRCPYH
YVEVMACPAGCLNGGGQLKA
PD-MPGKELLQQVERLYGLV
RTEA-PEDAPGIQELYERWL
QG-AGSERAGRLLHTSYHAV
EKAGSG--LSIRW
>gi_149750886_ref_XP_001496296.1_	Equus
--------------------
--------------------
------MASPFSGALQLTDL
DDFIGPSQDCIKPVKVDKR-
LGSGVAKIHIEDDGSYF-QV
GHDGGTRKLEKAKISLDDCL
ACSGCVTSAETVLITQQSHE
ELRKVLDA----NKTSAPGQ
QRLVVISVSPQSRASLAARF
QLN-----------------
-----PTDTARKLTTFFKKL
GAHYVFDTAFSRN-----FS
LLESQREFVRRFRGQA----
DSKQALPVLTSA--------
-----------CP---GWIC
YAEKT------------HGT
LLIPHLSTARSPQQVMGSLV
KDFFAQQQRLTPDKIYHVTV
MPCYDKKLEASRPDFFSQ--
---EHQTRDVDCVITT----
--------------------
--------------------
--GEVFKLLQEEGVLLSELE
PTPLDSL-------------
-------------------C
SSGSAQEPTSHQGGGSGGYL
EHVFRHAAQELFGV------
-HVTEVTYRPLRNKDFQEVT
LEREGQ--------------
------------VLLHFAMA
YGFRNIQNLVQKLK------
-------------RGRCPYH
YVEVMACPAGCLNGGGQLKA
PD-TADKELLQHVERLYSMV
RTEV-PEDVPGVQELYKRWL
QG-EGSEQAGRLLHTSYHAV
EKASSG--LSIRW
>gi_197100706_ref_NP_001124725.1_	Pongo
--------------------
--------------------
------MASPFSGALQLTDL
DDFIGPSQECIKPVKVEKR-
AGSGVAKIRIEDDGSYF-QI
NQDGGTRRLEKAKVSLNDCL
ACSGCITSAETVLITQQSHE
ELKKVLDA----NKMVAPSQ
QRLVVVSVSPQSRASLAARF
QLN-----------------
-----PTDTARKLTSFFKKI
GVHFVFDTAFSRH-----FS
LLESQREFVRRFRGQA----
DCKQALPLLASA--------
-----------CP---GWIC
YAEKT------------HGS
FILPHISTARSPQQVMGSLV
KDFFAQQQHLTPDKIYHVTV
MPCYDKKLEASRPDFFNQ--
---EHQTRDVDCVLTT----
--------------------
--------------------
--GEVFRLLEEEGVSLPDLE
PAPLDSL-------------
-------------------C
SGASAEEPTSHRGGGSGGYL
EHVFRHAARELFGI------
-HVAEVTYKPLRNKDFQEVT
LEKEGQ--------------
------------VLLHLAMA
YGFRNIQNLVQRLK------
-------------RGRCPYH
YVEVMACPSGCLNGGGQLQA
PD-RPSRELLQHVERLYGMV
RAEA-PEDAPGVQELYTHWL
QG-TDSECAGRLLHTQYHAV
EKASTG--LGIRW
>NP_071938.1
--------------------
--------------------
------MASPFSGALQLTDL
DDFIGPSQECIKPVKVEKR-
AGSGVAKIRIEDDGSYF-QI
NQDGGTRRLEKAKVSLNDCL
ACSGCITSAETVLITQQSHE
ELKKVLDA----NKMAAPSQ
QRLVVVSVSPQSRASLAARF
QLN-----------------
-----PTDTARKLTSFFKKI
GVHFVFDTAFSRH-----FS
LLESQREFVRRFRGQA----
DCRQALPLLASA--------
-----------CP---GWIC
YAEKT------------HGS
FILPHISTARSPQQVMGSLV
KDFFAQQQHLTPDKIYHVTV
MPCYDKKLEASRPDFFNQ--
---EHQTRDVDCVLTT----
--------------------
--------------------
--GEVFRLLEEEGVSLPDLE
PAPLDSL-------------
-------------------C
SGASAEEPTSHRGGGSGGYL
EHVFRHAARELFGI------
-HVAEVTYKPLRNKDFQEVT
LEKEGQ--------------
------------VLLHFAMA
YGFRNIQNLVQRLK------
-------------RGRCPYH
YVEVMACPSGCLNGGGQLQA
PD-RPSRELLQHVERLYGMV
RAEA-PEDAPGVQELYTHWL
QG-TDSECAGRLLHTQYHAV
EKASTG--LGIRW
>gi_61557212_ref_NP_001013201.1_	Rattus
--------------------
--------------------
------MASPFSGALQLTDL
DDFIGPSQSCIKPVTVAKK-
PGSGIAKIHIEDDGSYF-QV
NPDGRSQKLEKAKVSLNDCL
ACSGCVTSAETILITQQSHE
ELRKVLDA----NKVAAPGQ
QRLVVVSVSPQSRASLAARF
QLD-----------------
-----STDTARKLTSFFKKI
GVHFVFDTAFARN-----FS
LLESQKEFVQRFREQA----
NSREALPMLASA--------
-----------CP---GWIC
YAEKT------------HGN
FILPYISTARSPQQVMGSLI
KDFFAQQQLLTPDKIYHVTV
MPCYDKKLEASRPDFFNQ--
---EYQTRDVDCVLTT----
--------------------
--------------------
--GEVFRLLEEEGVSLSELE
PVPLDGL-------------
-------------------T
RSVSAEEPTSHRGGGSGGYL
EHVFRHAAQELFGI------
-HVADVTYQPMRNKDFQEVT
LEREGQ--------------
------------VLLRFAVA
YGFRNIQNLVQKLK------
-------------RGRCPYH
YVEVMACPSGCLNGGGQLKA
PD-TEGRELLQQVERLYSMV
RTEA-PEDAPGVQELYQHWL
QG-EDSERASHLLHTQYHAV
EKINSG--LSIRW
>gi_74211319_dbj_BAE26421.1_	Mus
--------------------
--------------------
------MASPFSGALQLTDL
DDFIGPSQNCIKPVKVAKK-
PGSGIAKIHIEDDGSYF-QV
NQDGRTQKLEKAKVSLNDCL
ACSGCVTSAETVLITQQSHE
ELRKVLDA----NKEAAPGQ
QRLVVVSISPQSRASLAARF
RLD-----------------
-----PTDTARKLTSFFKKI
GVHFVFDTAFARN-----FS
LLESQKEFVQRFREQA----
NSREALPVLASA--------
-----------CP---GWIC
YAEKT------------HGN
FILPYISTARSPQQVMGSLV
KDFFAQQQLLTPDKIYHVTV
MPCYDKKLEASRPDFFNQ--
---EYQTRDVDCVLTT----
--------------------
--------------------
--GEVFRLLEEEGVSLTELE
PAPLDGLDLSCVAPP-----
-----------ALTRPSPRT
SSVSAEEPSSHRGGGSGGYL
EHVFRHAAQELFGI------
-HVAEVTYQPLRNKDFQEVT
LEREGQ--------------
------------VLLRFAVA
YGFRNIQNLVQKLK------
-------------RGRCPYH
YVEVMACPSGCLNGGGQLKA
PD-TEGSELLQQLERLYSMV
RTEA-PEDAPGVQELYQHWL
QG-EDSERASRLLHTQYHAV
EKPSSG--LSIRW
>gi_148236349_ref_NP_001085771.1_	Xenopus
--------------------
--------------------
--------------------
----MKCENCTKTECSKKK-
KTEENGEIL---DAMALADG
EEKSEFHQLAEAKIFLSDCL
ACGNCVTSEEGAKIFAQNQK
ELFKVLNR----NKKCDSSL
HKLVVASISPQSVPYFAVKF
HLS-----------------
-----VCEASKKLCGFLKSL
GVHHVLDTTIAAD-----FS
ILETQKDFIQRFRRQT----
QDEHAFPMFASA--------
-----------CP---GWVQ
YAERV------------LGD
SVTPHICTAKSPQQIMGSLV
KGYFASSKNVSPDKIFHLMV
APCYDRKLEALREDYYTE--
---LYNCRDVDCVLTS----
--------------------
--------------------
--GEVMQIMEQQNISVKEVM
EFPLENL-------------
-------------------F
GETS-CVFVRHEGTSSDGYL
AHVFRHAAKELFDM------
-DVQEITYKALKNKDFLEVS
LEKDGE--------------
------------TVLRFAAA
YGFRNIQNMVLKLR------
-------------KGKFHYH
FVEVLACPGGCLNGKGQAQT
MDGKVERALLHEMEEVYTRV
PIQN-PESNPHIQALYEDWL
QG-AESQKTKQTLHTKIVAS
AQSAAR--LDMKW
>gi_114671181_ref_XP_511766.2_	Pan
--------------------
--------------------
--------------------
------MARAARASGAGRV-
ETKGAVMGPGQTGATGFAQA
LCKGEFHKLADAKIFLSDCL
ACDSCVTAEEGVQLSQQNAK
DFFRVLNL----NKKCDTSK
HKVLVVSVCPQSLPYFAAKF
NLS-----------------
-----VTDASRRLCGFLKSL
GVQVSVGSGPKISCQVSKFC
DVLMRSDWAVRLRERTL---
QGRSHFPVASRPAGSHDPQP
GHRGWVLGPAQAP---GWVR
YAERV------------LGR
PITAHLCTAKSPQQVMGSLV
KDYFARQQNLSPEKIFHVIV
APCYDKKLEALQESLPPA--
---LHGSRGADCVLTS----
--------------------
--------------------
--GEIAQIMEQGDLS---VR
DAAVDTL-------------
-------------------F
GDLKEDKVTRHDGASSDGHL
AHIFRHAAKELFNE------
-DVEEVTYRALRNKDFQEVT
LEKNGE--------------
------------VVLRFAAA
YGFRNIQNMILKLK------
-------------KGKFPFH
FVEVLACAGGCLNGRGQAQT
PDGHADKALLRQMEGIYADI
PVRR-PESSAHVQELYQEWL
EG-INSPKAREVLHTTYQSQ
ERGAHS--LDIKW
>gi_109119241_ref_XP_001113522.1_	Macaca
--------------------
--------------------
--------------------
----MKCEHCTRKECSKKT-
KTDDQENVSADAPSPAQ-EN
GEKGEFHKLADARIFLSDCL
ACDSCVTAEEGVQLSQQNAK
DFFRVLNL----NKKCDTSK
HKVLVVSVCPQSLPYFAAKF
NLS-----------------
-----VTDASRRLCGFLKSL
GVHYVFDTRIAAD-----FS
ILESQKEFVRRYRQHS----
EEERTLPMLTSA--------
-----------CP---GWVR
YAERV------------LGR
PITAHLCTAKSPQQVMGSLV
KDYFARQQNLSPEKIFHVIV
APCYDKKLEALQEGFPPA--
---LHGSRGADCVLTS----
--------------------
--------------------
--GEIAQIMDQGDLSVKDAA
STLCK---------------
-------------------F
GDLKEDKVTRHDGASSDGHL
AHIFRHAAKELFNE------
-DVEEVTYRALRNKDFQEVT
LEKNGE--------------
------------VVLRFAAA
YGFRNIQNMILKLK------
-------------KGKFPYH
FVEVLACAGGCLNGRGQAQT
PDGHADKALLRQMEGIYADI
PVRR-PESSAHMQELYQEWL
EG-INSPKAREVLHTTYQSQ
ERGAHS--LDIKW
>gi_14165461_ref_NP_114174.1_	Homo
--------------------
--------------------
--------------------
----MKCEHCTRKECSKKT-
KTDDQENVSADAPSPAQ-EN
GEKGEFHKLADAKIFLSDCL
ACDSCMTAEEGVQLSQQNAK
DFFRVLNL----NKKCDTSK
HKVLVVSVCPQSLPYFAAKF
NLS-----------------
-----VTDASRRLCGFLKSL
GVHYVFDTTIAAD-----FS
ILESQKEFVRRYRQHS----
EEERTLPMLTSA--------
-----------CP---GWVR
YAERV------------LGR
PITAHLCTAKSPQQVMGSLV
KDYFARQQNLSPEKIFHVIV
APCYDKKLEALQESLPPA--
---LHGSRGADCVLTSEISQ
AWWCTPVITATREAAARESL
EPGRQRLQRDKIAPLDSSLG
GGGEIAQIMEQGDLS---VR
DAAVDTL-------------
-------------------F
GDLKEDKVTRHDGASSDGHL
AHIFRHAAKELFNE------
-DVEEVTYRALRNKDFQEVT
LEKNGE--------------
------------VVLRFAAA
YGFRNIQNMILKLK------
-------------KGKFPFH
FVEVLACAGGCLNGRGQAQT
PDGHADKALLRQMEGIYADI
PVRR-PESSAHVQELYQEWL
EG-INSPKAREVLHTTYQSQ
ERGTHS--LDIKW
>gi_149637614_ref_XP_001513248.1_	Ornithorhynchus
--------------------
--------------------
---------MLSGPLIAASS
AFPPGRAKQRGDKGATLRR-
PPSSPGGCFLDD------SV
APKSEFHKLADAKIFLSDCL
ACDSCVTEEEGARVFQQNQK
EFFRVLNL----NKKCDTSK
HKVLAASICPQSLPYFAAKF
NLC-----------------
-----VTDTSRRLCGFLKSL
GVHYVFDTTIAAD-----FS
ILESQKEFVQRYRRRE----
QEEHALPMLTSA--------
-----------CP---GWVR
YAERV------------LAN
PVTLHICTAKSPQQIMGSLV
KDYFARQKNLSPDKIFHIIV
APCYDKKLEALREDFYTS--
---LYDSQDVDCVLTS----
--------------------
--------------------
--GEIVQILEQSGLSLNELE
EASVDTL-------------
-------------------F
GATTEGEVVRHDGTRSDGYL
EHVFKHAAKELFDM------
-DVQEITYRTLKNKDFQEVT
LERDGE--------------
------------VLLRFAAA
CGFRNIQNLVLKMK------
-------------RGRFPYH
FVEVLACPGGCLNGKGQMEA
GSGKPDGALLRRLEEAYAGI
PVRL-PEANAHVQRLYRDWL
QG-TDSPKVQAALHTSYGAA
EPPAPG--PHIKW
>gi_126309437_ref_XP_001368190.1_	Monodelphis
--------------------
--------------------
--------------------
----MKCENCTKKECIKKT-
KIDDHQSISVDTLNFYS-EH
EEKSEFHKLADAKIFLSDCL
ASDTCVTAEEGIRVFQQNQK
EFFRILNL----NKKCDSSH
HKVLAVSICPQSLPYFAAKF
NLS-----------------
-----ITDASKRLCGFLKSL
GVHYVFDSAIAAD-----FS
ILESQKEFVYRYRQQN----
QKEHSLPMFASA--------
-----------CP---GWIR
YAERV------------LGN
PVTPHICTAKSPQQIMGSLV
KDYFARQQNLSPAKIFHIIV
APCYDKKLEALREDFYTA--
---SYNSHDVDCVLTS----
--------------------
--------------------
--GEIIQIMEQKKEL---VK
EAAVDNL-------------
-------------------F
GEIKEGDIVQDGRTRSDGYL
EHIFKYAAKELFDM------
-DIKEITYKALKNKDFQEIS
LEKNGE--------------
------------IVLRFAAA
YGFRNIQNMVLKLK------
-------------KGKFPYH
FVEVLACPGGCLNGKGQTQT
EDGKPDKALLRRMEEVYAEI
PVQL-PETNTHVQRLYQEWL
DG-IDSPKVLEALHTTYSAA
EPPTDN--VDIKW
