>gi_225543245_ref_NP_001104687.2_	Danio
--------------------
--------------------
----------------MKSL
KAKFRKSDTHEWSKNDERLL
SAVEHGEADKVTSLLSKKGA
SPTK-------------LDS
EGKSALHAAATRGQTECLAV
ILAHGADVSLQDASGFTALH
LAAKNNHPECAKKLLQNKCV
VDAPDSSGRTA----LHHAA
ACGNNEIVQLL-CENKYHVN
LK--DSDGFTPLLLSARHAH
AEVCQSLLDWGADINARDKN
GRTAVMLAGESSCLAAVELL
VQRGADLHMVDSLGHDVLHY
TKLSGSGDVQTA--------
-----LNTALHRQQSE---S
DKSSVRSPQHGQKLNEDRSS
TPKKRKAPPP-PISPMQSPG
FTSPPYFTPSETPLSSNSES
SKR------------FNYKE
EELKSVALKDEIEKLHKEKS
MLLETIEDLKQIVEQTEPKT
EHSGKKDSSLIAALQAKIAS
LSLE-----NQQLAQIIKKR
PAPQGEEGQGSSRPNSIDSN
ASYHSTRADFELSSDTQIHT
GDEEDLSV---LDISGSSIK
LEMDEDVRLSQDREIGLLRD
ALENLQTKLIESKRENRSLH
ARLDTNSEKSLSED-GQKPQ
EELQLRGESAGAAEDNVLQK
FQYLKSCLEQEVKELKAKLI
KSQEVQKRDSCLIR---DLQ
AQLKNGHLSEEERQELKNTY
SALVENVNQEKTLLIEKYKE
SQEEIKMLQEALCGTVPVEA
AAKDFEEMKAELGEIIDGLQ
RRLLELSKSYSEAKSELSAA
RNQLQAKASE--SKDKTDVV
CVTKEEHEQKIQELVFKMKD
IQNVLKDTEAKHQAALKEIS
QVKQDAENQAQSSVTIADHT
--QVVASLGNAIK-------
--------------------
----N---------------
--LESEVELLKEQIE-QKTL
QVD-----------------
---ALQ---------NRLTV
EKDVTPDDSVSRLEYEQMRE
TLEGEMSDLKLLLKEALRKQ
DEMALEVTA-AWQEVKDS--
---RNERDAAQELAVRREQE
SSAVNSK-------------
--------------------
--------------------
----------------YREA
QDLITQLKKQVENHVVSERD
KNKKIDELSKEVMKLKEALN
S--LSQLSYTSSSPKRQQSQ
QVDSLQQQIKQLQYQLAETK
KRHHEIVSVYRMH------L
LYAVQGQMDEDVQKALKQI-
--------------------
-LVMCKMPAEAK--------
--------------------
--------------------
---
>gi_224090304_ref_XP_002194218.1_	Taeniopygia
--------------------
--------------------
----------------MKSL
KAKFRKSDTNEWNKNDDRLL
QAVENGDPEKVASLLGKKGA
SATK-------------QDS
EGKTVFHLAATKGHAECLRI
MVTHGADVTAQDGAGHSALH
LAAKNSHPDCVKRLLQSKCP
ADSTDNSGKTA----LHYAA
ACGCLQAVQLL-CEHKCPIN
IK--DLDGNIPLLLAVQNGH
TEVCKYLLDHGADINMRDKN
GRTALMMACEASSLNMVEAF
LRRGADVSLVDVFGQNALHY
AKLSENTGV-----------
-----QNLLSSKISQDMEAK
SPTKAKQHDQGSKLSSERSG
TPKKRKAPPP-PISPIQIND
LSSPH--SSTSTPMTGKGQA
FFADQVCKEEFSSLHRDNKD
RLSDSTTGADSLLDVSSE--
---ADQQDLLLLMQAKIASL
TLHNKELQDKLQERTPKEGD
SAVE-----SYSSQTQFEQT
AERQNEFLSQEMKPS-----
---------LNATQIQEKLT
SPREVKMY-IQEDLKDVQRK
LENSEAKRKHVETQVQSRVP
ETDNLNNPDISENCSDLNLK
FKETQNRHEEAVKE-ILNVQ
RQKKPVLVSSESEETGSDLS
MLKITYGEVEALKQELKKAL
EESERQKEKVRELQKKFEDR
EQKMAGKLSVEECEEMKNSY
CSVIDNINQEKALLIERYKE
GQEEIKRLQDKLTNQMQLES
-SAEAGERKDVMHRTIDELN
RQLSDLSQLYKEAQTELEDY
RKKK--------TLDDIASD
YIPRDEHDKLMEVTNSLKYK
AESELSEMKSQYTKVLGESK
ELKQLLDIQKQNSLPITEHR
--QVINALRNTIK-------
--------------------
----E---------------
--MEEEINELKRLLS-NKES
ELR-----------------
---NLE---------KALLE
EKAAINEAMVPKVTYEKLQS
SLEGEVSALSSKLKDVIREK
ENISLDAMKLRNEILHL---
---KETKEGMHTLLEAKERE
VSDLQHK-------------
--------------------
--------------------
----------------YHQV
QEALTELKNSSKL----EED
KDKKINEMSKEISKLKEALN
S--LSQLSYSTSAPKRQSQQ
LEVLQQ-QVKQLQNQLTETK
KQHQEIVSVYRMH------L
LYAVQGQMDEDVQKVLKQI-
--------------------
-LSMCKSQSQKK--------
--------------------
--------------------
---
>gi_37360330_dbj_BAC98143.1_	Mus
--------------------
--------------------
---QISQDFGRLNGLNMKSL
KAKFRKSDTNEWNKNDDRLL
QAVENGDAEKVASLLGKKGA
SATK-------------HDS
EGKTAFHLAAAKGHVECLKV
MVTHGVDVTAQDSSGHSALH
VAAKNGHPECIRKLLQYKSP
AENIDNSGKTA----LHYAA
AQGCLQAVQLL-CEHKSPIN
LK--DLDGNIPLLVAVQNGH
SEACHFLLDHGADVNSRDKN
GRTALMLACETGSSNTVDAL
IKKGADLSLVDSLGHNALHY
SKLSENAGI-----------
-----QNLLLSKISQDADLK
TPTKPKQHDQVSKISSERSG
TPKKRKAPPP-PISPTQLSD
VSSPR--SITSTPLSGKESV
FFAEAPFKAEISSI-QENKD
RLSDSTAGADSLLDISSE--
---ADQQDLLVLLQAKVASL
TLHNKELQDKLQAKSPKDKE
AEADLSFQSFHSTQTDLAPS
PGKASDIPSSDAKSS-----
---------PPVEHLAGTST
TDNDVIIRQLQDSLHDLQKR
LESSEAEKKQLQDELQSQRT
DTLCLNNTEISENGSDLSQK
LKETQSKYEEAMKE-VLSVQ
KQMKLGLLSQESADGYSHLR
EAPAD-EDIDTLKQDLQKAV
EESARNKERVRELETKLAEK
EQAEATKPPAEACEELRSSY
CSVIENMNKEKAFLFEKYQQ
AQEEIMKLKDTLKSQMPQEA
-PDDSGDMKEAMNRMIDELN
KQVSELSQLYREAQAELEDY
RKRK--------SLED-AAE
YIHKAEHERLMHVSNLSRAK
SEEALSEMKSQYSKVLNELT
QLKQLVDAHKENSVSITEHL
--QVITTLRTTAK-------
--------------------
----E---------------
--MEEKISALTGHLA-NKEA
EVA-----------------
---KLE---------KQLAE
EKAAVSDAMVPKSSYEKLQA
SLESEVNALATKLKESVRER
EKAHSEVAQ-VRSEVSQA--
---RREKDNIQTLLKAKEQE
VTALVQK-------------
--------------------
--------------------
----------------FQRA
QEELAGMRRCSETSSKLEED
KDEKINEMTREVLKLKEALN
S--LSQLSYSTSSSKRQSQQ
LDLLQQ-QVKQLQNQLAECK
KHHQEVISVYRMH------L
LYAVQGQMDEDVQKVLKQI-
--------------------
-LTMCKNQSQKK--------
--------------------
--------------------
---
>gi_74000873_ref_XP_544723.2_	Canis
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---------MKELIERRVN-
--------------------
--------------VRARNH
---VRTGALPN---------
--------------------
------WDAWIGTVPA---M
PLSCEGGG------------
-EGLSGIGVLPPCHQSL---
--------------------
--------------------
------HNPFHPADQL----
--------------SCNRRH
RGQGGGGPGR-QLAP---HT
LLSPR--QVGRVALH-----
---------------WA---
---AGAGHEQAVQLLLQH--
---EVAVDDEDAFG------
-----MNALLLSAWFGHLRI
LQIL-----VNSGAKIHCEN
KDGLTLLHCAAQKGH-----
---------VPV--------
-----LAF-----IMEDLED
VPLDRADKLGRTAFHRAAEH
G-------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------------------QL
DALDFLVGSGCDHSVKDKEG
NTALHLAASRGHLAVLQRLV
DIRL--------------DL
EEQNTKGLTALHAAAEGVHA
DCV----------QLLLEAG
SSVNALTQKKQSCLHYAALG
--GSEDVARALIH-------
--------------------
----A---------------
-GGQTNVADHQGASP-MHLA
VKH-----------------
---NFP-------ALVQLLI
DAGSDLDATDNRQ-QTPLHL
AAEHARQDIA-EM--LLIAR
VNLNLRDKQ-GKTALAVAA-
---RSNHTSLVDMIIKADRL
YKREKDH-------------
--------------------
--------------------
--------------------
-PLRREPSGKNLTFKQDHRQ
ERQQFHSVLWRLASRDLRPH
E--WKKLAYCWEFTDAHVHA
IEQQWT------------GT
KSYQEHGHRMLLI------W
LHGVAVASENPSKALFEGL-
--------------------
-VAIDRRDLAESVRKKANAD
PSAPSRCMAM----------
--------------------
---
>NP_113607.1
--------------------
--------------------
--------------------
---------MIVDKLLDDSR
GGEGLRDAAGGCGLMTSPL-
--------------------
--NLSYFYGASPPAAAPGA-
--------------------
--------------CDASCS
VLGPSAPGSPG--------S
DSSDFSSASSVSSCGAVESR
SR--GGARAERQPVEPHMGV
GRQQRG-PFQGVRVKNSVKE
LLLHIRSHKQKASGQAVDDF
KTQGVNIEQFRELKNTVSYS
GKRKGPDSLSDGPACKRPAL
LHSQFLTPPQTPTPGESMED
VHLNEPKQESSADLLQNIIN
IKNECSPVSLNTVQVSWLNP
VVVPQ--SSPAEQCQ-----
---------------DFHGG
QVFSPPQKCQPFQVRGSQ--
---QMIDQASLYQY------
-----SPQNQHVEQQPHYTH
KPTL-----EYSPFPIPPQS
PAYEPNLFDGPESQF-----
---------CPNQSLVSLLG
DQRESENI-----ANPMQTS
SSVQQQNDAHLHSFSMMPSS
ACEAMVGHEMASDSSNTSLP
FSNMGNPMN-----------
--------------------
--------------------
--------------------
--------------------
--------------------
-----TTQLGKSLFQWQVEQ
EESKLANISQDQFLSKDADG
DTFLHIAVAQGRRALSYVLA
RKMN-----------ALHML
DIKEHNGQSAFQVAVAANQH
LIV----------QDLVNIG
AQVNTTDCWGRTPLHVCAEK
--GHSQVLQAIQK-------
--------------------
----GAV---------GSNQ
F-VDLEATNYDGLTP-LHCA
VIAHNAVVHELQRNQQPHSP
EVQELLLKNKSLVDTIKCLI
QMGAAVEAKDRKSGRTALHL
AAEEANLELIRLFLELPSCL
SFVNAKAYN-GNTALHVAAS
LQYRLTQLDAVRLLMRKGAD
PSTRNLE-------------
--------------------
--------------------
--------------------
----------------NEQP
VHLVPDGPVGEQIRRILKGK
S--IQQRAPPY---------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---
>NP_006500.2
MLRSGPASGPSVPTGRAMPS
RRVARPPAAPELGALGSPDL
SSLSLAVSRSTDELEIIDEY
IKENGFGLDGGQPGPGEGLP
RLVSRGAASLSTVTLGPVAP
PATPPPWGCPLGRLVSPAPG
PGPQPHLVITEQPKQRGMR-
--------------------
--------------FRYECE
--GRSAGSILG----ESSTE
ASKTLPAIELRDCGGLREVE
VTACLVWKDWPHRVHPHSLV
GKDCTD-GICRVRLRPHVSP
RHSFNNLGIQCVRKKEIEAA
IERKIQLG------------
--------------------
-----IDPYNAGSLKN----
----HQEVDMNVVRICFQAS
YRDQQGQMRR--MDPVLSEP
VYDKK--STNTSELR-----
---------------ICRIN
KESGPCTGGEELYLLCDK--
---VQKEDISVVFS------
----------RASWEGRADF
SQAD-----VHRQIAIVFKT
PPYEDLEIVEPVTVN-----
---------VFLQRLTDGVC
SEPLPFTY-----LPRDHDS
YGVDKKRKRGMP--------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------DVL
GELNSSDPHGIESKRRKKKP
AIL-----------------
--DHFLPNHGS---------
--GPFLPPSALLP-------
--------------------
----DPD-------------
--FFSGTVSLPGLEP-----
--------------------
-------------PGGPDLL
DDGFAYDPTAPTLFTMLDLL
PPAPPHASAVVCS-----GG
AGAVVGETP-GPEPLTLDSY
QAPGPGDGGTASLV---GSN
MFPNHYR-------------
--------------------
--------------------
--------------------
--------------------
--------------------
---EAAFGGGLLSPGPEAT-
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---
>NP_002899.1
--------------------
--------------------
--------------------
--------------------
--------------------
-----------------MAS
GAYNPYIEIIEQPRQRGMR-
--------------------
--------------FRYKCE
--GRSAGSIPG----EHSTD
NNRTYPSIQIMNYYGKGKVR
IT--LVTKNDPYKPHPHDLV
GKDCRD-GYYEAEFGQERRP
-LFFQNLGIRCVKKKEVKEA
IITRIKAG------------
--------------------
-----INPFNVPEKQL----
--NDIEDCDLNVVRLCFQVF
LPDEHGNLTT-ALPPVVSNP
IYDNR--APNTAELR-----
---------------ICRVN
KNCGSVRGGDEIFLLCDK--
---VQKDDIEVRFV------
----------LNDWEAKGIF
SQAD-----VHRQVAIVFKT
PPYCK-AITEPVTVK-----
---------MQLRRPSDQEV
SESMDFRY-----LPDEKDT
YGNKAKKQKTTLLFQKLCQD
H-------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------VETGFRHVDQ
DGLELLTSGDPPTLASQSAG
ITVNFPERPRPGLLGSIGEG
RYFKKEPNLFSHDAVVREM-
---------------PTGVS
SQAESYYPSPGPISSGLSHH
ASM-----------------
--APLPSSSWSSVAHPTPRS
--GNTNPLSSFST-------
--------------------
--------------------
---RTLPSNSQGIPPFLRIP
VGN-----------------
---DLN-------ASNACIY
NNADDIVGMEASSMPSADLY
GISDPNM--------LSNCS
VNMMTTSSD-----------
---SMGETDNPRLLSMNLEN
PSCNSVL-------------
--------------------
--------------------
----------------DPRD
LRQLHQMSSSSMSAGANSNT
TVFVSQSDAFEGSDFSCADN
SM-INESGPSNSTNPNSHGF
VQDSQYSGIGSMQNEQLSDS
FPYEFFQV------------
--------------------
--------------------
--------------------
--------------------
--------------------
---
>NP_068810.3
--------------------
--------------------
--------------------
---------------MDELF
PLIFPAE-------------
------------------PA
QASGPYVEIIEQPKQRGMR-
--------------------
--------------FRYKCE
--GRSAGSIPG----ERSTD
TTKTHPTIKINGYTGPGTVR
IS--LVTKDPPHRPHPHELV
GKDCRD-GFYEAELCPDRCI
-HSFQNLGIQCVKKRDLEQA
ISQRIQTN------------
--------------------
-----NNPFQVPIEEQ----
----RGDYDLNAVRLCFQVT
VRDPSGRPLR--LPPVLSHP
IFDNR--APNTAELK-----
---------------ICRVN
RNSGSCLGGDEIFLLCDK--
---VQKEDIEVYFT------
----------GPGWEARGSF
SQAD-----VHRQVAIVFRT
PPYADPSLQAPVRVS-----
---------MQLRRPSDREL
SEPMEFQY-----LPDTDDR
HRIEEKRKRTYETFKS----
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------IMKKSPFSGPTDPR
PPPRRIAVPSRSSASVPKPA
PQPY---------PFTSSLS
TINYDEFPTMVFPSGQISQA
SAL---------------AP
APPQVLPQAPAPA-------
--PAPAMVSALAQ-------
--------------------
----A---------------
--------------P-APVP
VLA-----------------
-------------PGPPQAV
APPAPKPTQAGEGTLSEALL
QLQFDDEDLGALL------G
NSTDPAVFT------DLA--
---SVDNSEFQQLL-NQGIP
VAPHTTE-------------
--------------------
--------------------
--------------------
PMLMEYPEAITRLVTGAQRP
PDPAPAPLGAPGLPNGL---
---LSGDEDFSSIADMDFSA
LLSQISS-------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---
>NP_640332.1
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----MEAGPWRVSAPP----
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----------SGPPQFPAV
VPGPS---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---------LEVARAHMLAL
GPQQLLAQ------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------------DEEG
DTLLHLFAARGLRWAAYAAA
EVLQ-----------VYRRL
DIREHKGKTPLLVAAAANQP
LIV----------EDLLNLG
AEPNAADHQGRSVLHVAATY
--GLPGVLLAVLN-------
--------------------
----SGV---------Q---
--VDLEARDFEGLTP-LHTA
ILALNVAMRPSDLCPRVLST
QARDRL-------DCVHMLL
QMGANHTSQEIKSNKTVLHL
AVQAANPTLVQLLLELPRGD
LRTFVNMKAHGNTALHMAAA
LPPGPAQEAIVRHLLAAGAD
PTLRNLE-------------
--------------------
--------------------
--------------------
----------------NEQP
VHLLRPGPGPEGLRQLLKRS
R--VAPPGLSS---------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---
>NP_065390.1
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-----MFQAAERPQEWAME-
--------------------
--------------------
--GPRDG-------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---------LKKERLL----
----DDRHDSGLDSMKDEEY
EQMVK------ELQEIRLEP
QEVPR----GSEPWK-----
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-------------QQLTEDG
DSFLHLAIIHEEKALTMEVI
RQVK----------GDLAFL
NFQNNLQQTPLHLAVITNQP
EIA----------EALLGAG
CDPELRDFRGNTPLHLACEQ
--GCLASVGVLTQ-------
--------------------
----SCT---------TPHL
H-SILKATNYNGHTC-LHLA
SIH-----------------
---GYL-------GIVELLV
SLGADVNAQEPCNGRTALHL
AVDLQNPDLVSLL---LKCG
ADVNRVTYQ-GYSPYQLTW-
---GRPSTRIQQQL----GQ
LTLENLQ-------------
--------------------
--------------------
--------------------
------------MLPESEDE
ESYDTESEFTEFTEDELPYD
DCVFGGQRLTL---------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---
>gi_62644423_ref_XP_342347.2_	Rattus
--------------------
--------------------
--------------------
-----------MADDDPFGT
GQMFHLNTALTHSIFNAELY
STD--------------IPL
STDGPYLQILEQPKQRGFR-
--------------------
--------------FRYVCE
--GPSHGGLPG----ASSEK
NKKSYPQVKICNYVGPAKVI
VQ--LVTNGKNIHLHAHSLV
GKHCED-GICTVTAGPKDMV
-VGFANLGILHVTKKKVFET
LEARMTEACIRGYNPGLLVH
SDLAYLQAEGGG--------
-----DRQLTDREKEIIRQA
ALQQTKEMDLSVVRLMFTAF
LPDSTGSFTR-RLEPVVSDA
IYDSK--APNASNLK-----
---------------IVRMD
RTAGCVTGGEEIYLLCDK--
---VQKDDIQIRFY------
-----EEEENGGVWEGFGDF
SPTD-----VHRQFAIVFKT
PKYKDVNITKPASVF-----
---------VQLRRKSDLET
SEPKPFLY-----YPEIKDK
EEVQRKRQKLMPNFSDSFGG
G---------SGAGAGGGGM
FGSGGGGGGSTGSP-GPGYG
FPHYGFPAYGGIAFHPGATK
SNTGITHGTINTKFKNEPRD
CAKSDDREILNPP----EKE
TQGEGPSLFMASTKTEAIAP
ASTMEDKEEDVGFQDNLFLE
KALQLAKRHANALFDYAVTG
DVKMLLAVQRHLTAVQDENG
DSVLHLAIIHLHAQLVRDLL
EVTS--------GSISDDII
NMRNDLYQTPLHLAVITKQE
DVV----------EDLLRVG
ADLSLLDRWGNSVLHLAAKE
--GHDKILGVLLK-------
--------------------
-----------------NSK
AALLINHPNGEGLNA-IHIA
VMS-----------------
---NSL-------SCLQLLV
AAGAEVNAQEQKSGRTALHL
AVEYDNISLAGCL--LLEGD
ALVDSTTYD-GTTPLHIAA-
---GRGSTRLAALLKAAGAD
PLVENFEPLYDLDDSWEKAG
EDEGVVP-------------
--------------------
----------------GTTP
LDMAANWQVFDIL-NGKPYE
PVFTSDDILPQGDIKQLTED
T--RLQLCKLLEIPDPDKNW
ATLAQKLGLGILNNAFRLSP
APSKTLMDNYEVSGGTIKEL
VEALRQMGYTEAIEVIQAAF
RTPETTASSPVTTAQAHLLP
LSSSSTRQHIDELRDNDSVC
DSGVETSFRKLSFSESLTGD
GPLLSLNKMPHNYGQDGPIE
GKI
>NP_003989.2
--------------------
--------------------
--------------------
---------MAEDDPYLGRP
EQMFHLDPSLTHTIFNPEVF
QPQM-------------ALP
TADGPYLQILEQPKQRGFR-
--------------------
--------------FRYVCE
--GPSHGGLPG----ASSEK
NKKSYPQVKICNYVGPAKVI
VQ--LVTNGKNIHLHAHSLV
GKHCED-GICTVTAGPKDMV
-VGFANLGILHVTKKKVFET
LEARMTEACIRGYNPGLLVH
PDLAYLQAEGGG--------
-----DRQLGDREKELIRQA
ALQQTKEMDLSVVRLMFTAF
LPDSTGSFTR-RLEPVVSDA
IYDSK--APNASNLK-----
---------------IVRMD
RTAGCVTGGEEIYLLCDK--
---VQKDDIQIRFY------
-----EEEENGGVWEGFGDF
SPTD-----VHRQFAIVFKT
PKYKDINITKPASVF-----
---------VQLRRKSDLET
SEPKPFLY-----YPEIKDK
EEVQRKRQKLMPNFSDSFGG
G---------SGAGAGGGGM
FGSGGGGGGTGST--GPGYS
FPHYGFPTYGGITFHPGTTK
SNAGMKHGTMDTESKKDPEG
CDKSDDKNTVNLFGKVIETT
EQDQEPSEATVGNGEVTLTY
AT--GTKEESAGVQDNLFLE
KAMQLAKRHANALFDYAVTG
DVKMLLAVQRHLTAVQDENG
DSVLHLAIIHLHSQLVRDLL
EVTS--------GLISDDII
NMRNDLYQTPLHLAVITKQE
DVV----------EDLLRAG
ADLSLLDRLGNSVLHLAAKE
--GHDKVLSILLK-------
--------------------
----HKK---------AA--
--LLLDHPNGDGLNA-IHLA
MMS-----------------
---NSL-------PCLLLLV
AAGADVNAQEQKSGRTALHL
AVEHDNISLAGCL--LLEGD
AHVDSTTYD-GTTPLHIAA-
---GRGSTRLAALLKAAGAD
PLVENFEPLYDLDDSWENAG
EDEGVVP-------------
--------------------
----------------GTTP
LDMATSWQVFDIL-NGKPYE
PEFTSDDLLAQGDMKQLAED
V--KLQLYKLLEIPDPDKNW
ATLAQKLGLGILNNAFRLSP
APSKTLMDNYEVSGGTVREL
VEALRQMGYTEAIEVIQAA-
------SSPVKTTSQAHSLP
LSPASTRQQIDELRDSDSVC
DSGVETSFRKLSFTESLTSG
ASLLTLNKMPHDYGQEGPLE
GKI
>gi_213626267_gb_AAI70267.1_	Xenopus
--------------------
--------------------
--------------------
----MMSALKIENFDPYSCN
GIEDRNGMGYSTALLNPIVL
-----------------GQD
LANVAYLSIIEQPKQRGFR-
--------------------
--------------FRYVCE
--GPSHGGLPG----ASSEK
GKKTFPTVKIFNYVGMARIE
VD--LVTHTDPPRVHAHSLV
GKHSNETGNCIVTVGPEDMT
-AQFNNLGIVHVTKKSQTEI
LKEKMKRNILRNTGRNTLTE
VE------------------
-----ERKIEQEVKDL----
----KKVTDLSIVRLKFTAY
LPDSNGAYTL-ALPPVISDP
IHDSK--SPGASNLR-----
---------------ISRMD
KTAGSVKGGDEVYLLCDK--
---VQKDDIEVQFY------
-------EDDENGWHAFGDF
APTD-----VHKQYAIVFRT
PPYHTQKIDRPVTVF-----
---------LQLKRKKGGDV
SDSKQFTY-----YPLEQDK
EEVERKRRKDLPTFNNHFYG
G-------GSPMGGAGGGSS
FGQGGGSNINYQYT---GMN
SAFYMSSPAGGGYHSSGHMM
KHCSATNSSE----------
-----------------KNQ
QPSISIKKEGEEASACSQTD
SATTAQKEAQCQMIMRQANL
RMLSLTQRTSRALLDYATTA
DPRMLLAVQRHLTATQDENG
DTPLHLAVIHGQSSVIEQLV
QIIL--------SIPNQQIL
NMSNHLQQTPLHLGVITKQY
SVV----------AFLLKAG
ADPTILDRYGNSVLHLAVQS
--EDDKMLGVLLK-------
--------------------
----Y-----------PSVG
QKNLINMPDYHGLSP-VHWS
VKM-----------------
---KNE-------KCLVLLV
KAGANVNSAERKSGKSPLHI
AVEMDNLNLAVFL--VKKLH
ADINAKTYG-GNTPLHLAA-
---SRGSPMLTRMLVNEGAN
VLSENDEPVNKLPSCNSDTS
ESDSDVQMDTDSDHHGDSDT
DSSTAVDSECEHSAEEMHRR
EQRNIRPHCAMKRRYSGHTA
LDLTKSQKVRDILSKHTPGS
ASWKQKGPEP-VNVLALETN
T--VQRLEKLLNEGQTGADW
TELASRLRLQSLVETYKNTS
SPTESLLRNYELAGGNLKEL
INTLQSMGLNEGVELLCKS-
--------------------
-ETYAKHHSPAESKNDSAYE
SQSMEVDQSSGNLMDDSQKQ
TIPVSAAELCPTTEPTIGQ-
---
>gi_117320531_ref_NP_001070962.1_	Homo
--------------------
--------------------
--------------------
----------MESCYNPGLD
GIIEYDDFKLNSSIVEPKEP
-----------------APE
TADGPYLVIVEQPKQRGFR-
--------------------
--------------FRYGCE
--GPSHGGLPG----ASSEK
GRKTYPTVKICNYEGPAKIE
VD--LVTHSDPPRAHAHSLV
GKQCSELGICAVSVGPKDMT
-AQFNNLGVLHVTKKNMMGT
MIQKLQRQRLRSRPQGLTEA
E-------------------
-----QRELEQEAKEL----
----KKVMDLSIVRLRFSAF
LRASDGSFSL-PLKPVISQP
IHDSK--SPGASNLK-----
---------------ISRMD
KTAGSVRGGDEVYLLCDK--
---VQKDDIEVRFY------
-------EDDENGWQAFGDF
SPTD-----VHKQYAIVFRT
PPYHKMKIERPVTVF-----
---------LQLKRKRGGDV
SDSKQFTY-----YPLVEDK
EEVQRKRRKALPTFSQPFGG
G------SHMGGGSGGAAGG
YGGAGGGGSLGFFPSSLAYS
PYQSGAGPMGCYPGGGGGAQ
MAATVPSRDS----------
--------------------
--------GEEAAEPSAPSR
TPQCEPQAPEMLQRAREYNA
RLFGLAQRSARALLDYGVTA
DARALLAGQRHLLTAQDENG
DTPLHLAIIHGQTSVIEQIV
YVIH--------HAQDLGVV
NLTNHLHQTPLHLAVITGQT
SVV----------SFLLRVG
ADPALLDRHGDSAMHLALRA
GAGAPELLRALLQ-------
--------------------
----S-----------GAPA
VPQLLHMPDFEGLYP-VHLA
VRA-----------------
---RSP-------ECLDLLV
DSGAEVEATERQGGRTALHL
ATEMEELGLVTHL--VTKLR
ANVNARTFA-GNTPLHLAA-
---GLGYPTLTRLLLKAGAD
IHAENEEPLCPLPSPPTSDS
DSDSEGPEKDTRSSFR----
--------------------
----------------GHTP
LDLTCSTKVKTLLLNAAQNT
MEPPLTPPSPAGPGLSLGDT
A--LQNLEQLLDGPEAQGSW
AELAERLGLRSLVDTYRQTT
SPSGSLLRSYELAGGDLAGL
LEALSDMGLEEGVRLLRGP-
--------------------
-ETRDKLPSTAEVKEDSAYG
SQSVEQEAEK--------LG
PPPEPPGGLCHGHPQPQVH-
---
>gi_45383335_ref_NP_989744.1_	Gallus
--------------------
--------------------
--------------------
-----------MDEHFQPCL
DGIDYDDFSFGSHMVEQKEP
-----------------LME
TAVGPYLVIIEQPKQRGFR-
--------------------
--------------FRYGCE
--GPSHGGLPG----ASSEK
GHKTYPTVKICNYEGMARIE
VD--LVTHSDPPRVHAHSLV
GKQCNEAGNCVAIVGPKDMT
-AQFSNLGVLHVTKKNMMEI
MKEKLKKQKTRNTNGLLTEA
E-------------------
-----LREIELEAKEL----
----KKVMDLSIVRLRFTAY
LRDSSGNFTL-ALQPVISDP
IHDSK--SPGASNLK-----
---------------ISRMD
KTAGSVRGGDEVYLLCDK--
---VQKDDIEVRFY------
-------EDDENGWQAFGDF
SPTD-----VHKQYAIVFRT
PPYHKPKIDRPVTVF-----
---------LQLKRKRGGDV
SDSKQFTY-----YPVVEDK
EEVERKRKKVLPQFPQHFGG
G--------SHMGGAGGAGG
FGAGGGGNLSFPYSSGLGYN
NLYSSSPHPVGGGYQGGVQM
KAASESGD------------
--------------------
--------GDDRQAPTESTY
CRELQRHAHLCHLWL-----
----LARRNAHALLDYSVTA
DPRMLLAVQRHLAASQDENG
DTPLHLAIIHEQTAVIKQLI
EVVV--------SIPSQQII
NITNNLQQTPLHLAVITKQP
QVV----------QLLLQAH
ANPTLLDRYGNSLLHLALQA
--ADEEMLRMLLA-------
--------------------
----H-----------LGSA
TPYLLHLPNFQGLLP-VHLA
VKA-----------------
---KSP-------ACLDLLV
RKGADVNGVERQGGRTPLHL
AVEMENLNMATHL--VKKLG
ANVNSRTFA-GNAPLHLAA-
---GLGSPTLTKLLLKAGAD
VQRENDEPVSPSSSEASSDT
DGDPEEQEQEQAMELGEPAL
SPHPTPEEEQEEAGPRQRR-
----------------CHTA
LDLTRSQKVRDILLQASQPR
PDTELPTTPRAGNVLSLDSD
A--LQGLEQLLNQDGSGSDW
MELAKRLGLCSLVETYKDTP
SPSVSLLRSYELAGGSLGGL
LEALDSMGLRGAVRMLRKP-
--------------------
-EPLEKLQSTEVKEDSAYGS
ESVEEEQAAA--------LK
PRPVPEGELPHSQQQQQVH-
---
>NP_004547.2
--------------------
--------------------
--------------------
-------MNQRRSESRPGNH
RLQAYAEPGK----------
-----------------GDS
GGAGPLSGSARRGRGGGGAI
R-------------------
--------------VRRPCW
SGGAGRGGGPAWAVRLPTVT
AGWTWPALRTLSSLRAGPSE
PH-------SPGRRPPRAGR
-------PLCQADPQPGKAA
RRSLEPDPAQTGPRPARAAG
MSE-----------------
--------------------
-----ARKGPDEAEES----
------QYDSGIESLRSLRS
LPESTSAPAS-GPSDGSPQP
CTHPP--GPVKEP-------
--------------------
--------------------
---QEKED------------
---------------ADGER
ADS------TYGSSSLTYTL
SLLGGPEAEDPAPR------
---------LPLPHVGALSP
QQLEALTY------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------ISEDG
DTLVHLAVIHEAPAVLLCCL
ALLP------------QEVL
DIQNNLYQTALHLAVHLDQP
GAV----------RALVLKG
ASRALQDRHGDTALHVACQR
--QHLACARCLLE-------
--------------------
----GRPEPGRGTSHS----
--LDLQLQNWQGLAC-LHIA
TLQ-----------------
---KNQ-------PLMELLL
RNGADIDVQEGTSGKTALHL
AVETQERGLVQFL---LQAG
AQVDARMLN-GCTPLHLAA-
---GRGLMGISSTLCKAGAD
SLLRNVE-------------
--------------------
--------------------
--------------------
--------------------
--DETPQDLTEESLVLLPFD
D--LKISGKLLLCTD-----
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---
>NP_002494.2
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
MAGVACLGKAADADEWC---
--------------------
--------------------
-----DSGLGS---------
--------------------
--------------------
-------------LGPDAAA
--------------------
--------------------
--------------------
--------------------
--------------------
-----------PGGPGLGAE
L------GPGLS--------
--------------------
--------------------
--------------------
-------------WAPL---
--------------------
--------------------
--------------------
----VFGY------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------VTEDG
DTALHLAVIHQHEPFLDFLL
GFSA-----------GTEYM
DLQNDLGQTALHLAAILGET
STV----------EKLYAAG
AGLCVAERRGHTALHLACRV
--GAHACARALLQPRPRRPR
EAPDTYLAQGPDRTPDTNHT
PVALYPDSDLEKEEEESEED
WKLQLEAENYEGHTP-LHVA
VIH-----------------
---KDV-------EMVRLLR
DAGADLDKPEPTCGRSPLHL
AVEAQAADVLELL---LRAG
ANPAARMYG-GRTPLGSAM-
---LRPNPILARLLRAHGAP
EPEGEDE-------------
--------------------
--------------------
--------------------
-----KSGPCSSSSDSDSGD
EGDEYDDIVVHSSRSQTRLP
P--TPASKPLPDDPRPV---
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---
>NP_005169.2
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
MPRCPAGAMDEGPVDLRTR-
--------------------
--------------------
---PKAAGLPG---------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
------AALPLRKRPL----
--------------------
-----RAPSPEPAAPRGAAG
LVVPL---------------
--------------------
---DPLRGGCDLPAVPGP--
--------------------
---------------PHGLA
RPEA-----LYYPGALL---
PLYPTRAMGSPFPL------
---------VNLPTPL----
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
---------------YPMMC
PMEHPLSADIAMATRADEDG
DTPLHIAVVQGNLPAVHRLV
NLFQ----------QGGREL
DIYNNLRQTPLHLAVITTLP
SVV----------RLLVTAG
ASPMALDRHGQTAAHLACEH
--RSPTCLRALLD-------
--------------------
----SAA---------PGT-
--LDLEARNYDGLTA-LHVA
VNT-----------------
---ECQ-------ETVQLLL
ERGADIDAVDIKSGRSPLIH
AVENNSLSMVQLL---LQHG
ANVNAQMYS-GSSALHSAS-
---GRGLLPLVRTLVRSGAD
SSLKNCH-------------
--------------------
--------------------
----------------NDTP
LMVARSRRVIDILRGKATRP
ASTSQPDPSPDRSANTSPES
SSRLSSNGLLSASPSSSPSQ
SPPRDPPGFPMAPPNFFLPS
PSPPAFLPFAGVLRGPGRPV
PPSPAPGGS-----------
--------------------
--------------------
--------------------
--------------------
---
