>NP_001617.1
--------------------
--------------------
--------------------
-MNEVSVIKEGWLHKRGEYI
KTWRPRYFLLKSDGSFIGYK
ERPEAPD----------QTL
PPLNNFSVAE----CQLMKT
ERPRPNTFVIRCLQWTTVIE
RTFHVDSPDEREEWMRAIQM
VANSLKQRAPGEDPMDYKCG
SPSDSSTTEEMEVAVSKARA
KVTMNDFDYLKLLGKGTFGK
VILVREKATGRYYAMKILRK
EVIIAKDEVAHTVTESRVLQ
NTRHPFLTALKYAFQTHDRL
-----CFVMEYANGGELFFH
LSRERVFTEERARFYGAEIV
SALEYLHS-RDVVYRDIKLE
NLMLDK------------DG
HIKITDFGLCKEGISDGATM
KTFCGTPEYLAPEVLEDNDY
GRAVDWWGLGVVMYEMMCGR
LPFYNQDHERLFELILMEEI
RFPRTLSPEAKSLLAGLLKK
DPKQRLG-GGPSDAKEVMEH
RFFLSINWQDVVQKKLLPPF
KPQVTSEVDTRYFDDEFTAQ
SITITPPDRYD--SLGLLEL
DQRTHFPQFSYSASIREMN-
EVSVIKEGWLHKRGEYIKTW
RPRYFLLKSDGSFIGYKERP
EAPDQTLPPLNNFSVAECQL
MKTERPRPNTFVIRCLQWTT
VIERTFHVDSPDEREEWMRA
IQMVANSLKQRAPGEDPMDY
KCGSPSDSSTTEEMEVAVSK
ARAKVTMNDFDYLKLLGKGT
FGKVILVREKATGRYYAMKI
LRKEVIIAKDEVAHTVTESR
VLQNTRHPFLTALKYAFQTH
DRLCFVMEYANGGELFFHLS
RERVFTEERARFYGAEIVSA
LEYLHS-RDVVYRDIKLENL
MLDKDGHIKITDFGLCKEGI
SDGATMKTFCGTPEYLAPEV
LEDNDYGRAVDWWGLGVVMY
EMMCGRLPFYNQDHERLFEL
ILMEEIRFPRTLSPEAKSLL
AGLLKKDPKQRLGGGPSDAK
EVMEHRFFLSINWQDVVQ-K
KLLPPFKPQVTSEVDTRYFD
DEFTAQSITITPPDRYDS--
LGLLELDQRTHFPQFSYSAS
IREMNEVSVIKEGWLHKRGE
YIKTWRPRYFLLKSDGSFIG
YKERPEAPDQTLPPLNNFSV
AECQLMKTERPRPNTFVIRC
LQWTTVIERTFHVD-SPDER
EEWMRAIQMVANSLKQRAPG
EDPMDYKCGSPSDS---STT
EEMEVAVSKARAKVTMNDFD
YLKLLGKGTFGKVILVREKA
TGRYYAMKILRKEVIIAKDE
VAHTVTESRVLQ---NTRHP
FLTALKYAFQT---------
--------------------
--------------------
---------------HDRLC
FVMEYANGGELFFHLSRER-
----VFTEERARFYGAEIVS
ALEYLH-SRDVVYRDIKLEN
LMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPE
VLEDNDYGRAVDWWGLGVVM
YEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSL
LAGLLKKDPKQRLGG-GPSD
AKEVMEHRFFLSINWQDVVQ
KKLLPPFKPQVTSEVDTRYF
DDEFTAQSITITPPDRY--D
SLGLLEL--DQRTHFPQFSY
SASIRE--------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>NP_005456.1
--------------------
--------------------
--------------------
-MSDVTIVKEGWVQKRGEYI
KNWRPRYFLLKTDGSFIGYK
EKPQDVD----------L-P
YPLNNFSVAK----CQLMKT
ERPKPNTFIIRCLQWTTVIE
RTFHVDTPEEREEWTEAIQA
VADRLQRQE--EERMNCSPT
SQIDNIGEEEMDASTTHHK-
RKTMNDFDYLKLLGKGTFGK
VILVREKASGKYYAMKILKK
EVIIAKDEVAHTLTESRVLK
NTRHPFLTSLKYSFQTKDRL
-----CFVMEYVNGGELFFH
LSRERVFSEDRTRFYGAEIV
SALDYLHS-GKIVYRDLKLE
NLMLDK------------DG
HIKITDFGLCKEGITDAATM
KTFCGTPEYLAPEVLEDNDY
GRAVDWWGLGVVMYEMMCGR
LPFYNQDHEKLFELILMEDI
KFPRTLSSDAKSLLSGLLIK
DPNKRLG-GGPDDAKEIMRH
SFFSGVNWQDVYDKKLVPPF
KPQVTSETDTRYFDEEFTAQ
TITITPPEKYDEDGMDCMDN
ERRPHFPQFSYSASGREMS-
DVTIVKEGWVQKRGEYIKNW
RPRYFLLKTDGSFIGYKEKP
QDVDLPY-PLNNFSVAKCQL
MKTERPKPNTFIIRCLQWTT
VIERTFHVDTPEEREEWTEA
IQAVADRLQRQE--EERMNC
SPTSQIDNIGEEEMDASTTH
HKRK-TMNDFDYLKLLGKGT
FGKVILVREKASGKYYAMKI
LKKEVIIAKDEVAHTLTESR
VLKNTRHPFLTSLKYSFQTK
DRLCFVMEYVNGGELFFHLS
RERVFSEDRTRFYGAEIVSA
LDYLHS-GKIVYRDLKLENL
MLDKDGHIKITDFGLCKEGI
TDAATMKTFCGTPEYLAPEV
LEDNDYGRAVDWWGLGVVMY
EMMCGRLPFYNQDHEKLFEL
ILMEDIKFPRTLSSDAKSLL
SGLLIKDPNKRLGGGPDDAK
EIMRHSFFSGVNWQDVYD-K
KLVPPFKPQVTSETDTRYFD
EEFTAQTITITPPEKYDEDG
MDCMDNERRPHFPQFSYSAS
GREMSDVTIVKEGWVQKRGE
YIKNWRPRYFLLKTDGSFIG
YKEKPQDVDL-PYPLNNFSV
AKCQLMKTERPKPNTFIIRC
LQWTTVIERTFHVD-TPEER
EEWTEAIQAVADRLQRQEEE
R--MNC---SPTSQIDNIGE
EEMDASTTHHK-RKTMNDFD
YLKLLGKGTFGKVILVREKA
SGKYYAMKILKKEVIIAKDE
VAHTLTESRVLK---NTRHP
FLTSLKYSFQT---------
--------------------
--------------------
---------------KDRLC
FVMEYVNGGELFFHLSRER-
----VFSEDRTRFYGAEIVS
ALDYLH-SGKIVYRDLKLEN
LMLDKDGHIKITDFGLCKEG
ITDAATMKTFCGTPEYLAPE
VLEDNDYGRAVDWWGLGVVM
YEMMCGRLPFYNQDHEKLFE
LILMEDIKFPRTLSSDAKSL
LSGLLIKDPNKRLGG-GPDD
AKEIMRHSFFSGVNWQDVYD
KKLVPPFKPQVTSETDTRYF
DEEFTAQTITITPPEKYDED
GMDCMDN--ERRPHFPQFSY
SASGRE--------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>NP_005154.2
--------------------
--------------------
--------------------
-MSDVAIVKEGWLHKRGEYI
KTWRPRYFLLKNDGTFIGYK
ERPQDVD----------QRE
APLNNFSVAQ----CQLMKT
ERPRPNTFIIRCLQWTTVIE
RTFHVETPEEREEWTTAIQT
VADGLKKQE--EEEMDFRSG
SPSDNSGAEEMEVSLAKPKH
RVTMNEFEYLKLLGKGTFGK
VILVKEKATGRYYAMKILKK
EVIVAKDEVAHTLTENRVLQ
NSRHPFLTALKYSFQTHDRL
-----CFVMEYANGGELFFH
LSRERVFSEDRARFYGAEIV
SALDYLHSEKNVVYRDLKLE
NLMLDK------------DG
HIKITDFGLCKEGIKDGATM
KTFCGTPEYLAPEVLEDNDY
GRAVDWWGLGVVMYEMMCGR
LPFYNQDHEKLFELILMEEI
RFPRTLGPEAKSLLSGLLKK
DPKQRLG-GGSEDAKEIMQH
RFFAGIVWQHVYEKKLSPPF
KPQVTSETDTRYFDEEFTAQ
MITITPPDQDD--SMECVDS
ERRPHFPQFSYSASGTAMS-
DVAIVKEGWLHKRGEYIKTW
RPRYFLLKNDGTFIGYKERP
QDVDQREAPLNNFSVAQCQL
MKTERPRPNTFIIRCLQWTT
VIERTFHVETPEEREEWTTA
IQTVADGLKKQE--EEEMDF
RSGSPSDNSGAEEMEVSLAK
PKHRVTMNEFEYLKLLGKGT
FGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENR
VLQNSRHPFLTALKYSFQTH
DRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSA
LDYLHSEKNVVYRDLKLENL
MLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEV
LEDNDYGRAVDWWGLGVVMY
EMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLL
SGLLKKDPKQRLGGGSEDAK
EIMQHRFFAGIVWQHVYE-K
KLSPPFKPQVTSETDTRYFD
EEFTAQMITITPPDQDDS--
MECVDSERRPHFPQFSYSAS
GTAMSDVAIVKEGWLHKRGE
YIKTWRPRYFLLKNDGTFIG
YKERPQDVDQREAPLNNFSV
AQCQLMKTERPRPNTFIIRC
LQWTTVIERTFHVE-TPEER
EEWTTAIQTVADGLKKQEEE
E--MDFRSGSPSDN---SGA
EEMEVSLAKPKHRVTMNEFE
YLKLLGKGTFGKVILVKEKA
TGRYYAMKILKKEVIVAKDE
VAHTLTENRVLQ---NSRHP
FLTALKYSFQT---------
--------------------
--------------------
---------------HDRLC
FVMEYANGGELFFHLSRER-
----VFSEDRARFYGAEIVS
ALDYLHSEKNVVYRDLKLEN
LMLDKDGHIKITDFGLCKEG
IKDGATMKTFCGTPEYLAPE
VLEDNDYGRAVDWWGLGVVM
YEMMCGRLPFYNQDHEKLFE
LILMEEIRFPRTLGPEAKSL
LSGLLKKDPKQRLGG-GSED
AKEIMQHRFFAGIVWQHVYE
KKLSPPFKPQVTSETDTRYF
DEEFTAQMITITPPDQ--DD
SMECVDS--ERRPHFPQFSY
SASGTA--------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_73986656_ref_XP_542019.2_	Canis
MFSTGSRSRGGFTLCEYLAL
LLRGSYAWLWNSGHWKGAST
RGGLSVLQGGGSEGVLKRIG
DRNDSSVEGTGAARGRGGLA
RRGRSGRSRPERAARRRGLR
RARPFPAPRGAHARSSRRPS
LRAGTPGGRREDMASDAVQS
EPRSWSLLEQLGLAGADLAA
PGVQQQLELERERLRREIR-
--KELKLKE-----------
------GAENLRRATTDLG-
----RSLGPVELLLRGSSRR
LDLLHQQLQELHAHVVLPDP
AAAARDAPLSPGASGQAC-S
ATNLSRVAGLEKQLAIELKV
KQGAENMIQTYSNGS-----
-TKDRKLLLTAQQMLQ-DSK
TKIDIIRM---QLRRALQAG
QLESQAAPDEA-------QG
SPDLGAVELRIEELRHHFRV
EHAVAE--------------
-------GAKNVLRLLSAAK
AP----DRKAVSE----AQE
KL------TESNQKLGLLRE
ALERRLG-ELPADHPK----
---GRLLREELAAAS-SAAF
SARLA---------------
--GPFPPTPY----------
------STLCKPAPLTGTL-
EVRVVG--------------
--------------------
-----------------CKD
LPETIP-------WS-----
--------------------
--------------SSPVAG
VPGTP--DSRTTFLSRPARG
LYSR----------------
-----------SGSLSGRSS
LKVEAENTSEVSTVLKLDNT
VVGQTSWKPCGPSAWDQS--
----FTLELERARELELA--
---VFWRDQRGLCALKFLKL
EDFLDN--------------
----------ERHEVQL---
--------------DMEPQG
CLVAE-----------VTFR
NPVIERIPRLRRQKKIFSK-
--QQGKAFQRARQMNIDVAT
WVRLLR--------------
-----RLIPNATATSTFS-P
GASP--GPEVRSTGDIS---
--------------------
VEKLNLGTA-----------
--------------------
--------------------
----LDSL------PQKSPL
G-------------------
---------------PPSSP
SSLSSPIQETTTTPEPPSET
Q-------ETPGPAL-----
-----SSPLKKSPLTLEDFK
FLAVLGRGHFGKVLLSEFRP
SGELFAIKALKKGDIVARDE
VESLMCEKRILAAVTRAGHP
FLVNLFGCFQT---------
--------------------
--------------------
---------------PEHVC
FVMEYSAGGDLMLHIHSD--
----VFSEPRAVFYSACVVL
GLQFLH-EHKIVYRDLKLDN
LLLDTEGYVKIADFGLCKEG
MGFGDRTSTFCGTPEFLAPE
VLTDTSYTRAVDWWGLGVLL
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSAEAIGI
MRRLLRRNPERRLGS-SERD
AEDVKKQPFYRTLVWDSLLA
RRLPPPFVPTLSGRTDVSNF
DEEFTGEAPTLSPPRD----
-ARPLTA--AEQAAFRDFDF
VAGGC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_156229814_gb_AAI51830.1_	Danio
--------------------
--------------------
--------------------
--------------------
--------------------
-MAADSV-------------
-----------------QND
ARGPMVSGRLDFDQNLDFSD
TMVQKNLDEIKDQIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----SLAYVDNMLKKSNKK
VEELHQELQELNAHIVVKDP
EEVE-EYPLTPDTPKSETRM
STNSNRLAALKKQADIELKV
KQGAEDMIQMYSNGS-----
-SKDRKLLAAAQQMLQ-DSK
TKIEFIRM---QILKASQTS
EINYENNDVT--------TS
KPIISPLDLRIEELRHHYRI
ESAVAD--------------
-------GAKNVMKLLGTGK
VT----EKKAHSE----AQA
RL------NESSQKLDLLKF
SLEQRLS-ELPKNHPK----
---GTLIMEELAMVA-SPPN
SPRQS---------------
--IMSTSNQY----------
------STVAKPAALTGTL-
DVRLMG--------------
--------------------
-----------------CQD
LLENVPG------RS-----
--------------------
--------------KTASVS
LPGWSPSEARSSFMSRGNK-
--NK----------------
-----------SGS--SRTL
SKSD-DLSNEISAVLKLDNT
VVGQTHWKPVSNQSWDQK--
----FTLELDRSRELEIA--
---VYWRDWRSLCAVKFLRL
EDFLDN--------------
----------QRHGMCL---
--------------YLEPQG
TLFAE-----------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPSVNTS--FS-P
QAADLGSAMSHETAPMGHPD
---------AHSLPSDPT--
VTKLDFDKA-----------
--------------------
--------------------
----VTPP---S--KRNSIE
VEIEETAPPDKIS-------
-------------DGKEVQD
ALATFDF---LNNTVAKPDY
D----SLVEHEQPGLELTEI
QRKTEIREEEEVQFSLSDFK
CVAVLGRGHFGKVLLADYKT
TGEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------KEHVC
FVMEYAAGGDLMMHIHAD--
----VFSETRSVFYAACVVL
GLQFLH-DHKIVYRDLKLDN
LLLDTEGYVKIADFGLCKEG
MGFKDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLI
FEMLVGESPFPGDDEEEVFD
SIVNDEVRYPKYLSTEAISI
MRRLLRRNPERRLGA-GERD
AEEVKRHPFFRDMDWPGLLA
KKIRPPFVPTITSREDVSNF
DDEFTSEAPILTPPRE----
-PRILTL--GEQDLFADFDY
IADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_118094409_ref_XP_422357.2_	Gallus
--------------------
--------------------
--------------------
-----MVPKRRWSHGEGSCG
CT------------------
-IPPDPT----------AGG
FQLRVGPAGSARCNCYFSGD
AKSLLVSENLSTGQKLDFSD
TMVQQKLDEIKDQIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----NLAYVDNILKKSNKK
LEDLHHKLQELNAHIVVTDP
EDVA-DCPRTPDTPNSDPRF
PT-NNRLMALKKQLDIELKV
KQGAENMIQMYSNGS-----
-SKDRKLLATAQQMLQ-DSK
TKIEVIRM---QILQAVQTN
ELAFD-------------NA
KPVISPLELRMEELRHHFRI
EYAVAE--------------
-------GAKNVMKLLGSGK
VT----DRKALSE----AQA
RF------NESSQKLDLLKY
SLEQRLN-ELPKNHPK----
---SSIIIEELSLVS-SPTL
SPRQS---------------
--VISTQNQY----------
------STLSKPAALTGTL-
EVRLMG--------------
--------------------
-----------------CQD
ILENVPG------RS-----
--------------------
--------------KATSVT
LPGWSPNEVRTTFMGRTTK-
--AK----------------
-----------AGI--SKNL
LKTD-DLSNEVCAVLKLDNT
VVGQTSWKPISNQSWDQK--
----FTLELDRSRELEIS--
---VYWRDWRSLCAVKFLRL
EDFLDN--------------
----------QRHGMCL---
--------------YLEPQG
TLFAE-----------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPTVNHSGTFS-P
QAP---VPATVPVVDARIPE
---------LALQASDSP--
VAKLDFELE-----------
--------------------
--------------------
----PEPP---PAPPRASSL
GEICEPSSEMKAP-------
-------------D-MPAQD
DVSTFDFENGRNSIVPKLQP
G--IICESDVPHSDIKYTNI
REPEDRRTQQRFQFSLKDFR
CCAVLGRGHFGKVLLAEYKN
TNEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------KDHVC
FVMEYAAGGDLMMHIHTD--
----VFSEPRAVFYAACVVL
GLQYLH-EHKIVYRDLKLDN
LLLDTEGFVKIADFGLCKEG
MGFGDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLI
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSTEAISI
MRRLLRRNPERRLGA-GEKD
AEDVKKHHFFRLIDWNALLA
KKVKPPFVPTIRGREDVSNF
DDEFTSEAPILTPPRE----
-PRILSE--EEQEMFRDFDY
IADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_189163473_ref_NP_001099225.2_	Rattus
--------------------
--------------------
--------------------
--------------------
--------------------
-MASNPD----------RGE
ILL-----------TELQGD
SRPLPFSENVSAVQKLDFSD
TIVQQKLDDVKDRIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----NLAYVDNILKKSNKK
LEELHHKLQELNAHIVVSDP
EDSA-DCPRTPDTPNSDSRS
STSNNRLMALQKQLDIELKV
KQGAENMIQMYSNGP-----
-SKDRKLHGTAQQLLQ-DSK
TKIEVIRM---QILQAVQTN
ELAFD-------------NA
KPVISPLELRMEELRHHFRI
EFAVAE--------------
-------GAKNVMKLLGSGK
VT----DRKALSE----AQA
RF------NESSQKLDLLKY
SLEQRLN-ELPKNHPK----
---SSVVIEELSLVA-SPTL
SPRQS---------------
--MLSTQNQY----------
------STLSKPAALTGTL-
EVRLMG--------------
--------------------
-----------------CQD
ILENVPG------RS-----
--------------------
--------------KATSVA
LPGWSPSENRSSFMSRTSK-
--SK----------------
-----------SGS--SRNL
LKTD-DLSNDVCAVLKLDNT
VVGQTIWKPISNQSWDQK--
----FTLELDRSRELEIS--
---VYWRDWRSLCAVKFLRL
EDFLDN--------------
----------QRHGMCL---
--------------YLEPQG
TLFAE-----------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPTVNHSGTFS-P
QTP---VPATVPVVDARTPE
---------LAPPASDST--
VTKLDFDLE-----------
--------------------
--------------------
----PEAP---PAPPRASSL
GEI-DDSSELRVL-------
-------------D-IPGQG
SETVFDIENDRNNMRPKSKS
E----YELNIPDSSRSCWSV
GELEDKRSQQRFQFNLQDFR
CCAVLGRGHFGKVLLAEYKH
TNEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------KEHVC
FVMEYAAGGDLMMHIHTD--
----VFSEPRAVFYAACVVL
GLQYLH-EHKIVYRDLKLDN
LLLDTEGFVKIADFGLCKEG
MGYGDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLI
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSTEAISI
MRRLLRRNPERRLGA-GEKD
AEDVKKHPFFRLTDWSALLD
KKVKPPFVPTIRGREDVSNF
DDEFTSEAPILTPPRE----
-PRILLE--EEQEMFRDFDY
VADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_74222757_dbj_BAE42244.1_	Mus
--------------------
--------------------
--------------------
--------------------
--------------------
-MASNPD----------RGE
ILL-----------TELQGD
SRTLPFSENVSAVQKLDFSD
TMVQQKLDDIKDRIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----NLAYVDNILKKSNKK
LEELHHKLQELNAHIVVSDP
EDST-DCPRTPDTPNSDSRS
STSNNRLMALQKQLDIELKV
KQGAENMIQMYSNGS-----
-SKDRKLHGTAQQLLQ-DSK
TKIEVIRM---QILQAVQTN
ELAFD-------------NA
KPVISPLELRMEELRHHFKI
EFAVAE--------------
-------GAKNVMKLLGSGK
VT----DRKALSE----AQA
RF------NESSQKLDLLKY
SLEQRLN-ELPRNHPK----
---SSVVIEELSLVA-SPTL
SPRQS---------------
--MLSTQNQY----------
------STLSKPAALTGTL-
EVRLMG--------------
--------------------
-----------------CQD
ILENVPG------RS-----
--------------------
--------------KATSVA
LPGWSPSDNRSSFMSRTSK-
--SK----------------
-----------SGS--SRNL
LKTD-DLSNDVCAVLKLDNT
VVGQTSWKPISNQSWDQK--
----FTLELDRSRELEIS--
---VYWRDWRSLCAVKFLRL
EDFLDN--------------
----------QRHGMCL---
--------------YLEPQG
TLFAE-----------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPTVNHSGTFS-P
QTP---VPATVPVVDARIPD
---------LAPPASDST--
VTKLDFDLE-----------
--------------------
--------------------
----PEPP---PAPPRASSL
GET-DESSELRVL-------
-------------D-IPGQG
SETVFNIENDRNNLRPKSKS
E----YELSIPDSGRSCWGV
GELDDKRAQQRFQFSLQDFR
CCAVLGRGHFGKVLLAEYKH
TNEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------KEHVC
FVMEYAAGGDLMMHIHTD--
----VFSEPRAVFYAACVVL
GLQYLH-EHKIVYRDLKLDN
LLLDTEGFVKIADFGLCKEG
MGYGDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLI
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSTEAISI
MRRLLRRNPERRLGA-GEKD
AEDVKKHPFFRLTDWSALMD
KKVKPPFVPTIRGREDVSNF
DDEFTSEAPILTPPRE----
-PRILLE--EEQEMFHDFDY
VADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_115527928_gb_AAI25200.1_	Homo
--------------------
--------------------
--------------------
--------------------
--------------------
-MASNPE----------RGE
ILL-----------TELQGD
SRSLPFSENVSAVQKLDFSD
TMVQQKLDDIKDRIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----SLAYVDNILKKSNKK
LEELHHKLQELNAHIVVSDP
EDIT-DCPRTPDTPNNDPRC
STSNNRLKALQKQLDIELKV
KQGAENMIQMYSNGS-----
-SKDRKLHGTAQQLLQ-DSK
TKIEVIRM---QILQAVQTN
ELAFD-------------NA
KPVISPLELRMEELRHHFRI
EFAVAE--------------
-------GAKNVMKLLGSGK
VT----DRKALSE----AQA
RF------NESSQKLDLLKY
SLEQRLN-EVPKNHPK----
---SRIIIEELSLVAASPTL
SPRQS---------------
--MISTQNQY----------
------STLSKPAALTGTL-
EVRLMG--------------
--------------------
-----------------CQD
ILENVPG------RS-----
--------------------
--------------KATSVA
LPGWSPSETRSSFMSRTSK-
--SK----------------
-----------SGS--SRNL
LKTD-DLSNDVCAVLKLDNT
VVGQTSWKPISNQSWDQK--
----FTLELDR---------
--------------------
--------------------
--------------------
--------------------
----------------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPTVNHSGTFS-P
QAP---VPTTVPVVDVRIPQ
---------LAPPASDST--
VTKLDFDLE-----------
--------------------
--------------------
----PEPP---PAPPRASSL
GEI-DESSELRVL-------
-------------D-IPGQD
SETVFDIQNDRNSILPKSQS
E----YKPDTPQSGLEYSGI
QELEDRRSQQRFQFNLQDFR
CCAVLGRGHFGKVLLAEYKN
TNEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------KEHVC
FVMEYAAGGDLMMHIHTD--
----VFSEPRAVFYAACVVL
GLQYLH-EHKIVYRDLKLDN
LLLDTEGLVKIADFGLCKEG
MGYGDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLI
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSTEAISI
MRRLLRRNPERRLGA-SEKD
AEDVKKHPFFRLIDWSALMD
KKVKPPFIPTIRGREDVSNF
DDEFTSEAPILTPPRE----
-PRILSE--EEQEMFRDFDY
IADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_119593569_gb_EAW73163.1_	Homo
--------------------
--------------------
--------------------
--------------------
--------------------
-MASNPE----------RGE
ILL-----------TELQGD
SRSLPFSENVSAVQKLDFSD
TMVQQKLDDIKDRIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----SLAYVDNILKKSNKK
LEELHHKLQELNAHIVVSDP
EDIT-DCPRTPDTPNNDPRC
STSNNRLKALQKQLDIELKV
KQGAENMIQMYSNGS-----
-SKDRKLHGTAQQLLQ-DSK
TKIEVIRM---QILQAVQTN
ELAFDNGDGINCPPSYEHNA
KPVISPLELRMEELRHHFRI
EFAVAE--------------
-------GAKNVMKLLGSGK
VT----DRKALSE----AQA
RF------NESSQKLDLLKY
SLEQRLN-EVPKNHPK----
---SRIIIEELSLVAASPTL
SPRQS---------------
--MISTQNQY----------
------STLSKPAALTGTL-
EVRLMG--------------
--------------------
-----------------CQD
ILENVPG------RS-----
--------------------
--------------KATSVA
LPGWSPSETRSSFMSRTSK-
--SK----------------
-----------SGS--SRNL
LKTD-DLSNDVCAVLKLDNT
VVGQTSWKPISNQSWDQK--
----FTLELDRSRELEIS--
---VYWRDWRSLCAVKFLRL
EDFLDN--------------
----------QRHGMCL---
--------------YLEPQG
TLFAE-----------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPTVNHSGTFS-P
QAP---VPTTVPVVDVRIPQ
---------LAPPASDST--
VTKLDFDLE-----------
--------------------
--------------------
----PEPP---PAPPRASSL
GEI-DESSELRVL-------
-------------D-IPGQA
SQTVFDIQNDRNSILPKSQS
E----YKPDTPQSGLEYSGI
QELEDRRSQQRFQFNLQDFR
CCAVLGRGHFGKVLLAEYKN
TNEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------KEHVC
FVMEYAAGGDLMMHIHTD--
----VFSEPRAVFYAACVVL
GLQYLH-EHKIVYRDLKLDN
LLLDTEGFVKIADFGLCKEG
MGYGDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLI
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSTEAISI
MRRLLRRNPERRLGA-SEKD
AEDVKKHPFFRLIDWSALMD
KKVKPPFIPTIRGREDVSNF
DDEFTSEAPILTPPRE----
-PRILSE--EEQEMFRDFDY
IADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_194035781_ref_XP_001929459.1_	Sus
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
-MVQQKLDDIKDRIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----SLAYVDNILKKSNKK
LEELHHKLQELNAHIVVSDP
EDVS-DCPRTPDTPSSDPRC
STSNNRLMALQKQLDIELKV
KQGAENMIQMYSNGS-----
-SKDRKLHGTAQQLLQ-DSK
TKIEVIRM---QILQAVQTN
ELAFD-------------NA
KPVISPLELRMEELRHHFRI
EFAVAE--------------
-------GAKNVMKLLGSGK
VT----DRKALSE----AQA
RF------NESSQKLDLLKY
SLEQRLN-ELPKNHPK----
---SSVIIEELSLVA-SPTL
SPRQS---------------
--VISAQNQY----------
------STLSKPAALTGTL-
EVRLMG--------------
--------------------
-----------------CQD
ILENVPG------RS-----
--------------------
--------------KAASVA
LPGWSPSETRSSFMSRTSK-
--SK----------------
-----------SGS--SRNL
LKTD-DLSNDVCAVLKLDNT
VVGQTSWKPISNQSWDQK--
----FTLELDRSRELEIS--
---VYWRDWRSLCAVKFLRL
EDFLDN--------------
----------QRHGMCL---
--------------YLEPQG
TLFAE-----------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPTVNHSGTFS-P
QAP---VPAAVPVVDVRLPE
---------LAPPATDSA--
VTKLDFDLE-----------
--------------------
--------------------
----PVPP---PAPPRDSSL
GEV-DEAAELRDL-------
-------------D-TPGQD
SETLFDTENDRNSILPKSQS
E----YEPDIPQSGLEYSGI
HELEDRRSQQMFQFNLQDFR
CCAVLGRGHFGKVLLAEYKH
TNEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------TEHVC
FVMEYAAGGDLMMHIHTD--
----VFSEPRAAFYAACVVL
GLQYLH-EHKIVYRDLKLDN
LLLDTEGFVKIADFGLCKEG
MGYGDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLV
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSTEAISI
MRRLLRRNPERRLGA-GEKD
AEDVKKHPFFRLIDWSALMD
KKVKPPFVPTVRGREDVSNF
DDEFTSEAPILTPPRE----
-PRILSE--EEQEMFRDFDY
IADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_149709383_ref_XP_001495455.1_	Equus
--------------------
--------------------
--------------------
--------------------
--------------------
-MASNPE----------RAE
ILL-----------TELQGD
SRGLPFSENVSAVQKLDFSD
TMVQQRLDDIKDRIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----NLAYVDNILKKSNKK
LEELHHKLQELNAHIVVSDP
EDVT-DCPRTPDTPSSDPRC
STSNNRLMALQKQLDIELKV
KQGAENMIQMYSNGS-----
-SKDRKLHGTAQQLLQ-DSK
TKIEVIRM---QILQAVQTN
ELAFD-------------NA
KPVISPLELRMEELRHHFRI
EFAVAE--------------
-------GAKNVMKLLGSGK
VT----DRKALSE----AQA
RF------NESSQKLDLLKY
SLEQRLN-ELPKNHPK----
---SSIIIEELSLVA-SPTL
SPRQS---------------
--MISTQNQY----------
------STLSKPAALTGTL-
EVRLMG--------------
--------------------
-----------------CQD
ILENVPG------RS-----
--------------------
--------------KATSVA
LPGWSPSETRSSFMSRTSK-
--SK----------------
-----------SGS--SRNL
LKTD-DLSNDVCAVLKLDNT
VVGQTSWKPISNQSWDQK--
----FTLELDRSRELEIS--
---VYWRDWRSLCAVKFLRL
EDFLDN--------------
----------QRHGMCL---
--------------YLEPQG
TLFAE-----------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPTVNHSGTFS-P
QAP---VPATVPVVDVRIPE
---------LVPPASDST--
VTKLDFDLE-----------
--------------------
--------------------
----PEPP---PAPPRDSSL
GEI-NESAELRDL-------
-------------D-TPGQD
SETVFDIENDRNSILPKSQS
E----YEPDIPQSGLEYSGI
RELEDRRSQQMFQFNLQDFR
CCAVLGRGHFGKVLLAEYKH
TNEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------KEHVC
FVMEYAAGGDLMMHIHTD--
----VFSEPRAVFYAACVVL
GLQYLH-EHKIVYRDLKLDN
LLLDTEGFVKIADFGLCKEG
MGYGDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLI
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSTEAISI
MRRLLRRNPERRLGA-GEKD
AEDVKKHPFFRLIDWSALMD
KKVKPPFVPTIRGREDVSNF
DDEFTSEAPILTPPRE----
-PRILSE--EEQEMFRDFDY
IADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_119889898_ref_XP_883499.2_	Bos
--------------------
--------------------
--------------------
--------------------
--------------------
-MASNPE----------RGE
ILL-----------TELQGD
SRSLPFSENVSAVQKLDFSD
TMVQQKLDDIKDRIKREIR-
--KELKIKE-----------
------GAENLRKVTTDKK-
-----SLAYVDNILKKSNKK
LEELHHKLQELNAHIVVSDP
EDVT-DCPRTPDTPSSDSRC
STSNNRLMALQKQLDIELKV
KQGAENMIQMYSNGS-----
-SKDRKLHGTAQQLLQ-DSK
TKIEVIRM---QILQAVQTN
ELAFD-------------NA
KPVISPLELRMEELRHHFRI
EFAVAE--------------
-------GAKNVMKLLGSGK
VT----DRKALSE----AQA
RF------NESSQKLDLLKY
SLEQRLN-ELPKNHPK----
---SSIIIEELSLVA-SPTL
SPRQS---------------
--MISTQNQY----------
------STLSKPAALTGTL-
EVRLMG--------------
--------------------
-----------------CQD
ILENVPG------RS-----
--------------------
--------------KAASVA
LPGWSPSETRSSFMSRTSK-
--SK----------------
-----------SGS--SRNL
LKTD-DLSNDVCAVLKLDNT
VVGQTSWKPISNQSWDQK--
----FTLELDRSRELEIS--
---VYWRDWRSLCAVKFLRL
EDFLDN--------------
----------QRHGMCL---
--------------YLEPQG
TLFAE-----------VTFF
NPVIERRPKLQRQKKIFSK-
--QQGKTFLRAPQMNINIAT
WGRLVR--------------
-----RAIPTVNHSGTFS-P
QAP---VPATVPVVDVHIPE
---------LAPPASDST--
VTKLDFDLE-----------
--------------------
--------------------
----PEPP---PAPPRDSSL
GEI-DESA--RDL-------
-------------D-TPGQD
SETVFDTENDRNRILPKSQS
E----YEPDIPQSGLEYSGI
HELEDRRSQQMFQFSLQDFR
CCAVLGRGHFGKVLLAEYKH
TNEMFAIKALKKGDIVARDE
VDSLMCEKRIFETVNSVRHP
FLVNLFACFQT---------
--------------------
--------------------
---------------KEHVC
FVMEYAAGGDLMMHIHTD--
----VFSEPRAVFYAACVVL
GLQYLH-EHKIVYRDLKLDN
LLLDTEGFVKIADFGLCKEG
MGYGDRTSTFCGTPEFLAPE
VLTETSYTRAVDWWGLGVLI
YEMLVGESPFPGDDEEEVFD
SIVNDEVRYPRFLSTEAISI
MRRLLRRNPERRLGA-GEKD
AEDVKKHPFFRLIDWSALMD
KKVKPPFVPTIRGREDVSNF
DDEFTSEAPILTPPRE----
-PRILSE--EEQEMFRDFDY
IADWC---------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_148235251_ref_NP_001085794.1_	Xenopus
--------------------
--------------------
--------------------
--------------------
--------------------
----MRF----------NGS
LKLKI---------GEAVEL
QPTRWSMRHSVFKKGSYLLD
PYITINVDECRI--------
--------------------
------GQTSIKHRTNKPT-
----YNEEFCVTVSEGSKVE
LAVFHETPIGY---------
DDFVAHCTLSFEELIKGCAT
TDSFEGWVNLEPEGKLFVVI
-----TLIGTFTEGT-----
-MRDGRLIKHFTRKRQRAMR
RRVHQVNG---HKFMATYLK
QPTYCSH-----------CK
DFIWGVFG------KQGYQC
QVCTCV--------------
-------VHKRCHQLIVTAC
--------------------
--------TCKSNACKVEKQ
IFEQRFGINLPHKFRY----
---------HNYKV---PTF
CDHCG---------------
--------------------
------------SLLWGLV-
KQGLQ---------------
--------------------
-----------------CKM
CKMNVHK------RC-----
--------------------
--------------EANVAH
NCG-----------------
--------------------
--------------------
-----------VNSVELANA
LAGMGLHP------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----GNIPFK----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----QHSV------------
--------------------
--------------------
---SGSVDSDSNHLEEDSIS
N-------------------
-------TSSQYKFGIDDFT
FLRVLGKGSFGKVMLAKSKE
SDNLYAVKVLKKDVILQDDD
VECTMTEKRILSL--ACSHP
FLTQLFCCFQT---------
--------------------
--------------------
---------------LDRLF
FVMEFVNGGDLMFHIQKSR-
----RFDEARACFYSAEITS
ALMFLH-DKGVIYRDLKLDN
VLLDHEGHCKLADFGMCKEG
IREGCTTSTFCGTPDYIAPE
ILQEMQYGPLVDWWAMGVLL
YEMLCGHAPFEAENEDDLFE
AILNDEVVYPGWLSQDSVEI
LQAFMKKKPTKRLGSLTLGG
EKAILWHPFFKDINWDELNK
KAIEPPFRPRIKAREDVSNF
DPEFIKEDAVLTPIDE----
--SLLPM--INQEEFRNFSY
TAPELQNTSQDGSAQMPQ--
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_156119425_ref_NP_001095195.1_	Oryctolagus
--------------------
--------------------
--------------------
--------------------
--------------------
--MADPA----------AGQ
PPS-----------------
--------------------
--------------------
--------------------
--------------------
--------------EGEEST
VRFARK--------------
--------------------
--------------------
-------------GA-----
-LRQKNVHEVKN--------
-----------HKFTARFFK
QPTFCSH-----------CT
DFIWG-FG------KQGFQC
QVCCFV--------------
-------VHKRCHEFVTFSC
PG---ADKGPASD-------
-------DPRSKHKFKIHTY
SS------------------
-----------------PTF
CDHCG---------------
--------------------
------------SLLYGLI-
HQGMK---------------
--------------------
-----------------CDT
CMMNVHK------RC-----
--------------------
--------------VMNVPS
LCGTDHTERR----------
--------------------
----------------GRIY
IQAH--IDREVLIVVVRDAK
NLVPMDPNGLSDPYVKLK--
--------------------
--------------------
--------------------
--------------------
---------------LIPDP
KSESK-----------QKTK
TIKCSLNPEWNETFRFQLK-
------ESDKDRRLSVEIWD
WDLTSR--------------
-----NDFMGSLSFGISELQ
KAGVDGWFKLLSQEEGEYFN
---------VPVP-------
--------------------
--------------------
--------------------
----PEGS------------
--------------------
-----------------EGN
EELRQKFERAKIGQGTKTPE
E-------------KTTNTI
SKFDNNGNRDRMK--LTDFN
FLMVLGKGSFGKVMLSERKG
TDELYAVKILKKDVVIQDDD
VECTMVEKRVLAL--PGKPP
FLTQLHSCFQT---------
--------------------
--------------------
---------------MDRLY
FVMEYVNGGDLMYHIQQVG-
----RFKEPHAVFYAAEIAI
GLFFLQ-SKGIIYRDLKLDN
VMLDSEGHIKIADFGMCKEN
IWDGVTTKTFCGTPDYIAPE
IIAYQPYGKSVDWWAFGVLL
YEMLAGQAPFEGEDEDELFQ
SIMEHNVAYPKSMSKEAVAI
CKGLMTKHPGKRLGC-GPEG
ERDIKDHAFFRYIDWEKLER
KEIQPPYKPKARDKRDTSNF
DKEFTRQPVELTPTDK----
-LFIMNL--DQNE-FAGFSY
TNPEFVINV-----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
>gi_109127926_ref_XP_001095880.1_	Macaca
--------------------
--------------------
--------------------
--------------------
--------------------
--MADPA----------AGP
PPS-----------------
--------------------
--------------------
--------------------
--------------------
--------------EGEEST
VRFARK--------------
--------------------
--------------------
-------------GA-----
-LRQKNVHEVKN--------
-----------HKFTARFFK
QPTFCSH-----------CT
DFIWG-FG------KQGFQC
QVCCFV--------------
-------VHKRCHEFVTFSC
PG---ADKGPASD-------
-------DPRSKHKFKIHTY
SS------------------
-----------------PTF
CDHCG---------------
--------------------
------------SLLYGLI-
HQGMK---------------
--------------------
-----------------CDT
CMMNVHK------RC-----
--------------------
--------------VMNVPS
LCGTDHTERR----------
--------------------
----------------GRIY
IQAH--IDRDVLIVLVRDAK
NLVPMDPNGLSDPYVKLK--
--------------------
--------------------
--------------------
--------------------
---------------LIPDP
KSESK-----------QKTK
TIKCSLNPEWNETFRFQLK-
------ESDKDRRLSVEIWD
WDLTSR--------------
-----NDFMGSLSFGISELQ
KASVDGWFKLLSQEEGEYFN
---------VPVP-------
--------------------
--------------------
--------------------
----PEGS------------
--------------------
-----------------EGN
EELRQKFERAKISQGTKVPE
E-------------KTTNTV
SKFDNNGNRDRMK--LTDFN
FLMVLGKGSFGKVMLSERKG
TDELYAVKILKKDVVIQDDD
VECTMVEKRVLAL--PGKPP
FLTQLHSCFQT---------
--------------------
--------------------
---------------MDRLY
FVMEYVNGGDLMYHIQQVG-
----RFKEPHAVFYAAEIAI
GLFFLQ-SKGIIYRDLKLDN
VMLDSEGHIKIADFGMCKEN
IWDGVTTKTFCGTPDYIAPE
IIAYQPYGKSVDWWAFGVLL
YEMLAGQAPFEGEDEDELFQ
SIMEHNVAYPKSMSKEAVAI
CKGLMTKHPGKRLGC-GPEG
ERDIKEHAFFRYIDWEKLER
KEIQPPYKPKARDKRDTSNF
DKEFTRQPVELTPTDK----
-LFIMNL--DQNE-FAGFSY
TNPEFVINV-----------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
--------------------
----------
