>XP_001714076.1
--------------------
--------------------
-----MTYTDSKNLS-DVFL
VNQHI---------------
-----------CEANQNIYQ
NEYIFAD-ANFATA------
----HDGPDLA---------
--------------------
--------------------
--------------------
--------------------
-------------------C
NTPRDLAVV------PLDTG
HLTAASNAEVRAS-------
--------------------
-----------PEVPDGSGA
TGS---KGGTWATATPQLLS
EEDLPWHCDLYQDTCR-GDF
------WQSEPGKCEGGPWG
RRLGTMRAAEAGN-------
--------------------
--------------------
-------ECEAHEEFEEKGR
AEGDELNGEHE---------
--------------------
-------------GSHINNI
LPQHIQQWQ-----------
-----RSPCIANEHGKKMLE
HIHHKQQNTYTCLKDMEHHF
HELEAIILHGKQ--------
--------QAV------NKG
EKGSKDLQIFCASCRR-PIS
KRVTFHHMEHCFAKYECQLP
VGSLYPTCIERATW------
--------------------
-------LFCDVYNLKSKRY
CKRLQVLCPEHSWDPK----
------MSKDEVGGCPLVH-
---------------NVFEF
TGNFCCLPKCLCNHHYSWEK
LRRA-VDLECMQAVRCHAEG
AEGWGRILDSLSHIQVPQLH
KLEQLFEQEQKVRTSMMNRV
GLLALMLHGTIQHDPFTSDL
CSRQVHIEAKLYLCTECGSA
FTKKLSLLTHQKTHTGEKLC
TD-----------------
>gi_47206826_emb_CAF86999.1_	Tetraodon
--------------------
--------------------
----APVYCVCRRPDINCFM
IG------------------
-----------CDSCTEWFH
GTCIGIS-EKTAKAIRVWYC
PSCRGQ--CLCDRLQSRKHR
GH------------------
--------------------
--------------------
-----------------THT
HTHTHTHTHTHTHTHTRLQP
LLCVYEVRYSALAVIPSSAD
QDPSL---EIKYR-------
--------------------
-----------PKKNKEKKE
TGVEREERSEDESSSPPPKI
DRR-----------RV-SQL
------WHSE----EEDPQL
E-SLRKKAVKVKHVKRREKK
TEKKKSVAAP----------
--------------------
------KEEAKPRHHKAKQR
HRERVRHSERAGEG-GAKEV
AGALRQCLGPGCVQ-PARAN
SKYCSEDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCVAEEMGRRQLE
RIRKEQQADAVRLTLMEKRF
HELEGIIAVAKQ--------
--------QQVQHHEEVTEG
EGDDTDLQIFCVSCSH-PVN
PKVALRHMERVYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPKVAPN
VFGPR-VTADEVCGCPLVK-
---------------DVFEP
TGEFCRVSKRKCNKHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNLRMAMTNRA
GLLALMLHQTIQHDPITTDL
RSAKER--------------
--------------------
-------------------
>gi_169145302_emb_CAQ14103.1_	Danio
------------------MD
SEVSDFEQP--PGPE--RTL
IRGNAPVYCVCRRPDINCFM
IG------------------
-----------CDSCSEWFH
GDCIKIS-EKTAKTIRVWYC
EKCRSKDETLEVKYRPKKSR
EK---------EAETDGPDT
QPDTPDFKSDGRRGSR----
--------------------
-----------------IKR
SARMCGECEACLRTEDCGLC
DFCKDMKKFGG----PNKIR
QKCRLRQCEVRAR-------
--------------------
---------KMLRVKEEEYS
MSKSRDYQD-------GPLS
EEYSENELELYQQYCA-GQY
GDNSTGWNSD---DDDGSYG
ESSLRKKAVKVKHVKRREKR
SEKSEKKK------------
--------------------
-------EENKSRKHKPKQK
HRDRVRHSERA----EVRD-
SGGARQCLGPGCVE-AARAN
SKYCSDDCGMKLAANRICEI
LPQRIQQWQ-----------
-----QSPCIAEEQGKKFLE
RIRREQQLARMRLTEMEKRF
HELEGIIAKAKQ--------
--------QVVQYDEEVNEG
D-DDTDLQIFCVSCSH-SVN
PKVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------IPADEVCGCPLVR-
---------------DVFEP
TGEYCRVSKRKCNKHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVKTAMTNRA
GLMALMLHQTIQHDPITTDL
RTSKDR--------------
--------------------
-------------------
>gi_74144768_dbj_BAE27361.1_	Mus
------------------ME
GDGSDLEPP--DAGDDSKSE
NGENAPIYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GDCIRIT-EKMAKAIREWYC
RECREKDPKLEIRYRHKKCR
ERD-GSERAGSEPRDEGGGR
KRPASDPELQRRAGSGTGVG
AMLARGSASPHKSSPQPLVA
TPSQHH-HQQQQQQQQQIKR
SARMCGECEACRRTEDCGHC
DFCRDMKKFGG----PNKIR
QKCRLRQCQLRARESYKYFP
SSLSPVTPSEALPRPRRPPP
TQQQPQQSQKLGRIREDEGT
VLSSVVKEPPEATATPEPLS
DEDLALDPDLYQDFCA-GAF
DDHGLPWMSD---AEESPFL
DPALRKRAVKVKHVKRREKK
SEKK----------------
--------------------
-------KEERYKRHRQKQK
HKDKWKHPERA----DAKD-
PASLPQCLGPGCVW-AAQPG
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCIAEEHGKKLLE
RIRREQQSARTRLQEMERRF
HELEAIILRAKQ--------
--------QAVREDEENNEN
DSDDTDLQIFCVSCGH-PIN
PRVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPLVR-
---------------DVFEL
TGDFCRLPKRQCNRHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVRTAMTNRA
GLLALMLHQTIQHDPLTTDL
RSSADR--------------
--------------------
-------------------
>gi_119226197_ref_NP_001073166.1_	Rattus
------------------ME
GDGSDLEPP--DAGEDSKSE
NGENAPIYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GDCIRIT-EKMAKAIREWYC
RECREKDPKLEIRYRHKKCR
ERD-GSERDGSEPRDEGGGR
KRPASDPELQRRAGSGTGVG
AMLARGSASPHKSSPQPLVA
TPSQHHQQQQQQQQQQQIKR
SARMCGECEACRRTEDCGHC
DFCRDMKKFGG----PNKIR
QKCRLRQCQLRARESYKYFP
SSLSPVTPSEALPRPRRPPP
TQQQPQQSQKLGRIREDEGT
VLSSVVKEPPEATATPEPLS
DEDLALDPDLYQDFCA-GAF
DDH-VPWMSD---AEESPFL
DPALRKRAVKVKHVKRREKK
SEKK----------------
--------------------
-------KEERYKRHRQKQK
HKDKWKHPERA----DAKD-
PASLPQCLGPGCVR-AAQPG
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCIAEEHGKKLLE
RIRREQQSARTRLQEMERRF
HELEAIILRAKQ--------
--------QAVREDEENNEN
DSDDTDLQIFCVSCGH-PIN
PRVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPLVR-
---------------DVFEL
TGDFCRLPKRQCNRHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVRTAMTNRA
GLLALMLHQTIQHDPLTTDL
RSSADR--------------
--------------------
-------------------
>gi_66792822_ref_NP_001019688.1_	Bos
------------------ME
GDASDPEPP--DAGEDSKSE
NGENAPIYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GDCIRIT-EKMAKAIREWYC
RECREKDPKLEIRYRHKKSR
ERD-SSERDGSEPRDEGGGR
KRPAPDPDLQRRAGAGTGVG
AMLARGSASPHKSSPQPLVA
TPSQHH---QQQQQQQQIKR
SARMCGECEACRRTEDCGHC
DFCRDMKKFGG----PNKIR
QKCRLRQCQLRARESYKYFP
SSLSPVTPSESLPRPRRPLP
TQPQPQPSQKLGRLREDEGA
VASAAVKEPPEATATPEPLS
DEDLPLDSELYQDFCA-GAF
DDHSLPWMSD---TEESQFL
DPALRKRAVKVKHVKRREKK
SEKK----------------
--------------------
-------KDERYKRHRQKQK
HKDKWKHPERA----DAKD-
PASLPQCLGPGCVR-AAQPG
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCIAEEHGKKLLE
RIRREQQSARTRLQEMERRF
HELEAIILRAKQ--------
--------QAVREDEESNEG
DSDDTDLQIFCVSCGH-PIN
PRVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPLVR-
---------------DVFEL
TGDFCRLPKRQCNRHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVRTAMTNRA
GLLALMLHQTIQHDPLTTDL
RSNAER--------------
--------------------
-------------------
>gi_109122179_ref_XP_001093242.1_	Macaca
------------------ME
GDGSDPEPP--DAGEDSKSE
NGENAPIYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GDCIRIT-EKMAKAIREWYC
RECREKDPKLEIRYRHKKSR
ERD-GNERDGSEPRDEGGGR
KRPVPDPDLQRRAGSGTGVG
AMLARGSASPHKSSPQPLVA
TPSQHH---QQQQQQ--IKR
SARMCGECEACRRTEDCGHC
DFCRDMKKFGG----PNKIR
QKCRLRQCQLRARESYKYFP
SSLSPVTPSESLPRPRRPLP
TQQQPQPSQKLGRIREDEGA
VASSAVKEPPEATATPEPLS
DEDLPLDPDLYQDFCA-GAF
DDHGLPWMSD---TEESPFL
DPALRKRAVKVKHVKRREKK
SEKK----------------
--------------------
-------KEERYKRHRQKQK
HKDKWKHPERA----DAKD-
PASLPQCLGPGCVR-PAQPS
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCIAEEHGKKLLE
RIRREQQSARTRLQEMERRF
HELEAIILRAKQ--------
--------QAVREDEESNEG
DSDDTDLQIFCVSCGH-PIN
PRVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPLVR-
---------------DVFEL
TGDFCRLPKRQCNRHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVRTAMTNRA
GLLALMLHQTIQHDPLTTDL
RSSADR--------------
--------------------
-------------------
>gi_114673136_ref_XP_001154017.1_	Pan
------------------ME
GDGSDPEPP--DAGEDSKSE
NGENAPIYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GDCIRIT-EKMAKAIREWYC
RECREKDPKLEIRYRHKKSR
ERD-GNERDSSEPRDEGGGR
KRPVPDPDLQRRAGSGTGVG
AMLARGSASPHKSSPQPLVA
TPSQHH---QQQQQQ--IKR
SARMCGECEACRRTEDCGHC
DFCRDMKKFGG----PNKIR
QKCRLRQCQLRAR-------
--LSPVTPSESLPRPRRPLP
TQQQPQPSQKLGRIREDEGA
VASSTVKEPPEATATPEPLS
DEDLPLDPDLYQDFCA-GAF
DDHGLPWMSD---TEESPFL
DPALRKRAVKVKHVKRREKK
SEKK----------------
--------------------
-------KEERYKRHRQKQK
HKDKWKHPERA----DAKD-
PASLPQCLGPGCVR-PAQPS
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCIAEEHGKKLLE
RIRREQQSARTRLQEMERRF
HELEAIILRAKQ--------
--------QAVREDEESNEG
DSDDTDLQIFCVSCGH-PIN
PRVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPLVR-
---------------DVFEL
TGDFCRLPKRQCNRHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVRTAMTNRA
GLLALMLHQTIQHDPLTTDL
RSSADR--------------
--------------------
-------------------
>gi_156142182_ref_NP_001095124.1_	Homo
------------------ME
GDGSDPEPP--DAGEDSKSE
NGENAPIYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GDCIRIT-EKMAKAIREWYC
RECREKDPKLEIRYRHKKSR
ERD-GNERDSSEPRDEGGGR
KRPVPDPDLQRRAGSGTGVG
AMLARGSASPHKSSPQPLVA
TPSQHH---QQQQQQ--IKR
SARMCGECEACRRTEDCGHC
DFCRDMKKFGG----PNKIR
QKCRLRQCQLRARESYKYFP
SSLSPVTPSESLPRPRRPLP
TQQQPQPSQKLGRIREDEGA
VASSTVKEPPEATATPEPLS
DEDLPLDPDLYQDFCA-GAF
DDHGLPWMSD---TEESPFL
DPALRKRAVKVKHVKRREKK
SEKKVMER------------
--------------------
-------KEERYKRHRQKQK
HKDKWKHPERA----DAKD-
PASLPQCLGPGCVR-PAQPS
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCIAEEHGKKLLE
RIRREQQSARTRLQEMERRF
HELEAIILRAKQ--------
--------QAVREDEESNEG
DSDDTDLQIFCVSCGH-PIN
PRVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPLVR-
---------------DVFEL
TGDFCRLPKRQCNRHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVRTAMTNRA
GLLALMLHQTIQHDPLTTDL
RSSADR--------------
--------------------
-------------------
>gi_194214673_ref_XP_001499266.2_	Equus
------------------ME
GDGSDPEPP--DAGEDSKSE
NGENAPIYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GDCIRIT-EKMAKAIREWYC
RECREKDPKLEIRYRHKKSR
DRD-SNERDGSEPRDEGGGR
KRPAPDPDLQRRAGSGTGVG
AMLARGSASPHKSSPQPLVA
TPSQQQ---QQQQQQ--IKR
SARMCGECEACRRTEDCGHC
DFCRDMKKFGG----PNKIR
QKCRLRQCQLRARESYKYFP
SSLSPVTPSESLPRPRRPLP
TQQQPQSSQKLGRIREDEGA
VASAAVKEPPEATATPEPLS
DEDLPLDPDLYQDFCA-GAF
DDHGLPWMSD---TEESPFL
DPALRKRAVKVKHVKRREKK
SEKKVMET------------
--------------------
-------KEERYKRHRQKQK
HKDKWKHPERA----DAKD-
PASLPQCLGPGCVR-PAQPG
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCIAEEHGKKLLE
RIRREQQSARTRLQEMERRF
HELEAIILRAKQ--------
--------QAVREDEESNEG
DSDDTDLQIFCVSCGH-PIN
PRVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPLVR-
---------------DVFEL
TGDFCRLPKRQCNRHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVRTAMTNRA
GLLALMLHQTIQHDPLTTDL
RSSADR--------------
--------------------
-------------------
>gi_73962141_ref_XP_861089.1_	Canis
------------------ME
GDGSDPEPP--DAGEDSKSE
NGENAPIYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GDCIRIT-EKMAKAIREWYC
RECREKDPKLEIRYRHKKSR
ERD-SNERDGSEPRDEGGGR
KRPAPDPDLQRRAGSGTGVG
AMLARGSASPHKSSPQPLVA
TPSQQQ---QQQQQQ--IKR
SARMCGECEACRRTEDCGHC
DFCRDMKKFGG----PNKIR
QKCRLRQCQLRARESYKYFP
SSLSPVTPSESLPRPRRPLP
TQQQPQPSQKLGRIREDEGA
VASSAVKEPPEATATPEPLS
DEDLPLDPDLYQDFCA-GAF
DDHGLPWMSD---TEESPFL
DPALRKRAVKVKHVKRREKK
SEKKVMERVK----------
--------------------
------WKEERYKRHRQKQK
HKDKWKHPERA----DAKD-
PASLPQCLGPGCVR-PAQPG
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCIAEEHGKKLLE
RIRREQQSARTRLQEMERRF
HELEAIILRAKQ--------
--------QAVREDEESNEG
DSDDTDLQIFCVSCGH-PIN
PRVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPKVRFA
LSSSHSVPADEVCGCPLVR-
---------------DVFEL
TGDFCRLPKRQCNRHYCWEK
LRRAEVDLERVRV-------
---W---------------Y
KLDELFEQERNVRTAMTNRA
GLLALMLHQTIQHDPLTTDL
RSSADR--------------
--------------------
-------------------
>gi_89273390_emb_CAJ82153.1_	Xenopus
VTERDPEAEVDVVATGGEME
SEFSDADLT--AAGD---TE
DGENAPVYCICRKPDINCFM
IG------------------
-----------CDNCNEWFH
GHCINIT-EKMAKAIREWYC
VQCRDKHPHLEIKYRHKKSK
ER----ERETEKDENEETAK
NE-------KKKSGSTSSSS
NKVPR---------------
---------QQ------IKR
SARMCGECEACSRTEDCGQC
DFCRDMKKFGG----PNKIR
QKCRLRQCQVRAR-------
--------------------
---------KMLRVKDDDLS
LF----RDTPEPSSLAGSLS
DDDLPLDPELYQELCAGGAF
DDHNLPWLSD---TDDTPFL
DSVMRKRAVKVKHVKRREKK
ADKK----------------
--------------------
-------KDEKYKRHKQKQR
HKDKTKHSERT----EIRD-
FSSLRQCLGPSCVQ-PARSS
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCVAEEQGKKLLE
RIRREQQQARTKLQNMESRF
HELEALISKAKQ--------
--------QQIREDEETNEG
DSDDTDLQIFCVSCGH-PIN
PKVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPHSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPMVK-
---------------DVFEL
TGDFCRVPKRKCNRHYCWEK
LRRAEVDLERVRL-------
---W---------------Y
KLDELFEQERNVRMAMTNRA
GLLALMLHQTIQHDPVTTDL
RTHTER--------------
--------------------
-------------------
>gi_147899828_ref_NP_001085408.1_	Xenopus
------------------ME
SEFSDADLT--TARD---TE
DGENAPVYCICRKPDINCFM
IG------------------
-----------CDHCNEWFH
GHCINIT-EKMAKAIREWYC
MQCREKYPHLEIKYRHKKSK
ERERETEKDENEETTKNEKK
KSSTSSNKVPRQQ-------
--------------------
-----------------VKR
SARMCGECESCSRTEDCGQC
DFCRDMKKFGG----PNKIR
QKCRLRQCQVRAR-------
--------------------
---------KMLRVKDDDLS
MY----RDTPEPSSLAGSLS
DDDLPLDPELYQELCAGGAF
DDHNLPWLSD---TEDTPFL
DSVMRKRAVKVKHVKRREKK
ADKK----------------
--------------------
-------KDDKYKRHKQKQR
HKDKTKHSERM----ETRD-
FSSLRQCLGPSCVQ-PARAN
SKYCSDDCGMKLAANRIYEI
LPQRIQQWQ-----------
-----QSPCVAEEQGKKLLE
RIRREQQQARTKLQNMESRF
HELEALISKAKQ--------
--------QQIREDEETNEG
DSDDTDLQIFCVSCGH-PIN
PKVALRHMERCYAKYESQTS
FGSMYPTRIEGATR------
--------------------
-------LFCDVYNPQSKTY
CKRLQVLCPEHSRDPK----
------VPADEVCGCPMVK-
---------------DVFEL
TGDFCRVPKRKCNRHYCWEK
LRRAEVDLERVRL-------
---W---------------Y
KLDELFEQERNMRMAMTNRA
GLLALMLHQTIQHDPVTTDL
RTHTER--------------
--------------------
-------------------
