>gi|113206060|ref|NP_001038102.	Gallus gallus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------------------------------------------MTPSS
QPDPINTFVCKCIINRQPRMKKASRSVGSVPKVPGVNKTQ-----TTEKTKPESGSSLSA
VTKLS-KPGTSASLL------KTKSNDDLLAGMASGGGVTMTNGVKAKKSTCASTVSSTT
GTTMSTLENKPRTVAGSTA--RRSTSSGTKES--SSS--RERI-----RDRSRLSQSKKL
PLAGQGSN---DTVLAK-----RSRSRTNPESDIRMSK----SKSDNQISDKAALEAKVN
DLLTLAKTKDVEILH-LRNELRDMR----------AQLGLNEDQ-VEGDEKSEEKEA---
-IVVHQPTDVESTLLQLQE-----QNTAIREELNQLKNENRMLKD--RLNALGFSLEQRL
DNSEKLFGYQSLSPE-ITAGNHSDGG-------GTLTSSVEGSAPGS--MEDLLSQDEHT
LMDNQHSNSMDNLDSECSEVYQPLTSSDDA-----LDAPS----SSESEG-VPS--IERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTAEELQATLQELADLQQITQELNSENE
RLGEEKVILMESLCQQSDK-LEHFSRQIEYFRSLL--DEHHISYV-IDEDMKS--GRYME
LEQRYMDLAENARF-----EREQLLGVQQHLSNTLKMAEQDN------------KEAQEM
IGALK-ERNHHM----------------------ERIIESEQKSKTAIAST---------
-------------------LEEYKATVASDQ--------IEMNRLKA------QLEHEKQ
KVAE--LYSIH----------------NSGDK-SDIQD----LLESVRLDKEKAETLAS-
-------------------------------SLQEELAHTRNDANRL------QDAIA--
------------------KVEDEYRVFQEEA----------------KKQ---IEDLNV-
-TLEKLRAELDEKETERSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENTVKKL-----QDQKHD----MEREIKNLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLKRRLHEA--QEKNEKLTKE--LEEIKSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPT--PTVKTLIK
SFDSAS--QVPSPAAAT---------IPRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPISASKPLATLTDKRPSYAEIPVQ-EHLLRTSSTSRP-ASLPRV--------PAMESA
KSISVSRRSSEEIK---RDISAPDGASPASLMAMGTTSPQLS--LS---SSPTASVTPTT
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCAVLHTYLP---AHIPYQELNSQD---------------------KRRNF---
--------TLAFQAAESV-GIKSTLDINEMVRTER-PDWQNVMLYVTAIY-----KYFET
----------------------
>gi|116007118|ref|NP_001036254.	Drosophila melanogaster
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------MIKLKSLFRRGQGNSSSHSSNSSHKQQQ--NSSNNNRQKSQSSTSLNT
AHEQQ-QQHSITAATTKFYAHQETASYERGVDVG-----------------------DEG
ALLLTNQQQEQRRQQQQLLQQPQSNTLPQKKS-------KLKG-----QKQPKLLPVQQP
HSNAPEPH-----DPQQ-----PLMTSLAAVPQASATG----SSSNSNINNNNALAALQD
GGAAAAAAADFYQQL-AAAATATAT----------ATSANGSNTSADSPVSSFPAAAAAV
AVAAVAASSYQQQQQQQQLLNNEQQQQQLLEANNKMQELHKQME---RFRSEQMQLETRI
TE---LLPYQSEVAK-LK---------------GDLVKMQSLQEKSQMEIGNLKYENESL
RNRLRDVVNSPLSDAEKHQIIQDSQRLHSSAPAS-IALPSTHDAHDGTPCLTPD--WDKQ
-----S----SSSEISVACLQDKIIQMEETHYSTNEELQATLQELADLQTQLTDTQTENE
RLAEEKDVLFQSLCRQTEK-LNESRTQISTLQELLLRDTKQPA-----PEVSA-----SE
REQKLLDLIKTSQE-----EREAVLLKQEELGAELAEMKQAR------------EAGQLE
LQRQR-ERIALL----------------------DSQLDAANAERRQGEAQ---------
-------------------FSQAMEEISQRA--------IEISRLST------LLENARS
KIEE--LEADL----------------SRGDK-TDLSE----VLDVARKEKDALEERVA-
-------------------------------ELQDQCSRSQAELRRL------RDQLS--
------------------GLTEECKVVKNNA----------------KCA---VSHLEY-
-RLEQLQRDKDKIAGEWQA--------------LEERVAELQVQCKCHQE----------
------------------------------------------------------------
----------------------------------DKAQLQ-----------SLLA-----
--------E---TQRHLGDV-----QLKLGE----AECRLDQETQLRRKEAEE-WQQFQ-
---ADLLMTVRVAND-FKTEALSAREQLVLDNKTQ--KEKIRLLEQQ--LEKLTKQ----
--QMQQSETPQ-----SVLSTVQR--EMEMATRRSKLSFSRQDSR-------LSVKTLIE
SIENNKA-QGKADESESHYSSTSSLNSGTPDLGTTPI-----IFPPSS-----DWH----
---ESIRLPVLQSTNLHVNVGNEVGAGQGTNTSSGSGGDLASTTK---------ATLPLR
DQQQLAITSTQSQV---QNVSQPSTPATP-------SSAGSS-------SSGGLPFGNVS
KSFISGERKD------PLNMLAKN-GGS--KRNALLKWCQNKTVGYRNI---DITNFSSS
WNDGLAFCAILHSYLP---DRIPYDQLTPAN---------------------KRRNF---
--------SLAFAAAESV-GIGTTLNINDMCQIER-PDWMQVMSYVTAVY-----KYFET
----------------------
>gi|86515432|ref|NP_001034544.1	Rattus norvegicus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MKKANRSAGSVPKVSGISKPQ-----TVEKSKSENSSSAPT
GGKPV-KPGAAAALS------KTKSNDDLLAGMA--GGVNVTNGVKAKKSNCSSAAPSAP
APAMTISESKSKSSTGTSSSAKRSTSAGNKES--SST--RERL-----RERTRLNQSKKL
PSVSQGAN---DVALAK-----RSRSRTATEGDIRMSK----SKSDNQISDKAALEAKVK
DLLTLAKTKDVEILH-LRNELRDMR----------AQLGISEDH-CEGEDRSEEKET---
-IIAHQPTDVESTLLQLQE-----QNTAIREELNQLKNENRMLKD--RLNALGFSLEQRL
DNSEKLFGYQSLSPE-ITPGNQSDGG-------GTLTSSVEGSAPGS--VEDLLSQDENT
LMAHQHSNSMDNLDSECSEVYQPLTSSDDA-----LDAPS----SSESEG-VPS--IERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENE
RLGEEKVILMESLCQQSDK-LEHFGRQIEYFRSLL--DEHHISYV-IDEDVKS--GRYME
LEQRYMDLAENARF-----EREQLLGVQQHLSNTLKMAEQDN------------KEAQEM
IGALK-ERSHHM----------------------ERIIESEQKGKAALAAT---------
-------------------LEEYKATVASDQ--------IEMNRLKA------QLEKEKQ
KVAE--LYSIH----------------NSGDK-SDIQD----LLESVRLDKEKAETLAS-
-------------------------------SLQEDLAHTRNDANRL------QDTIA--
------------------KVEDEYRAFQEEA----------------KKQ---IEDLNM-
-TLEKLRSELEEKETERSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENTVKKL-----QDQKHD----LERENKTLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLKRRLHEA--QEKNEKLTKE--LEEIKSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPT--PTVKTLIK
SFDSAS--QVPNAAAAA---------IPRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPVSTSKPLTALSDKRSNYGEIPGQ-EHLLRTSSTSRP-ASLPRV--------PAMESA
KTISVSRRSSEEMK---RDISASEGASPASLMAMGTTSPQLS--LS---SSPTASVTPST
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELNSQE---------------------KKRNF---
--------TLAFQAAESV-GIKSTLDINEMARTER-PDWQNVMLYVTAIY-----KYFET
----------------------
>gi|156544432|ref|XP_001607603.	Nasonia vitripennis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MSEAQESAATTPRCDEPTEKKLFGGGGAVPDVHQRPAGQQQ
QQQQQ-KPVAAAPAT-----RQQVGECNLLPVLV--ERLRSALELSCSSSSCDDQLPLED
SGVDSEEDFRLWNTAGLVAATGAAATTGKPKL--DLKFLEDILLADIHTALARLQDTLKR
VDIGTLTRYNASLDPSNKLYLLRLISNLLAKLKVPEEAIVQGDEPEHGAAHQGRFHNRRR
KNERHTIGVSAEEIARAKRWFDEKSVSSNDSSSPSRVEGIADKDLVVGSSSIERIVEGAP
SATAVETPAIEDKLVVLQE--------TAPTPMKPGTFSDKCMKD--AINQQQCKSNREQ
ENS---ARYDPLERV-LTAPRRFDGLC------KDDSSIADGFQERS--AASFYQQQQPH
HSGPRH----NKFTAKKSKIKRANT----------IDIPNYLKLKSDSPDQVQNGCFALR
RPIDVG----DRLTN---GHHQRVVPSFEPKTENDRKFLALINKNNSNAETATSQTANGS
PFKSFNYRQAATVADKNWS-NRFWNIKTNFDKPTRSEGEEELPRKPGKLDVRKKFENRDD
SLEREAMLVGSLRV----MPQKQVNGFTHAPTSPFQKIEKPV------------AKQPET
GPPFL-KAAGYM----------------------PKNNNMLQAKLKMFDQE---------
-------------------PAKSNAETRAKS------KFGKPPENKKPSAPSQPLENGQL
NYYS--FCKQFAPFASGRS--------NANEGKSNVNSTKSKLLENIQKETDKPEP----
-------------------------------AKRDRPKVPTTQSSSQ------QHDFS--
------------------KQYSYHKPYEGYA----------------YQD---YRQLEKK
PQFNSPRGSFQAQEADFVK--------------PEKPPRRFAEASTQNVA----------
------------------------------------------------------------
----------------------------------VQTTLESCTDRRPSAPELLVSSSVEH
PVPQPRKRNSVSVQTTSPSLLSPVNYNAQTSTSPSITSPIPHAHQAFKPAN---YSGYH-
---APMPADQVPRNY-YSNGSSYDYNAYPCK------SNQHEVLSPK--PTPAVPE----
-----TPQLQG--ISQKLYNEFSKLPDSNPAPRGPSFDYGKIDAPACDEAKILAFKPTVY
PYEDPVGKPLPDVVEEN---------IENQDISSDGI-----VTRYTCAIATISPD----
-----SPEPASDKAPRRRTSAATS------TRSSVTTCSSSSSSK---------PMSPFA
KFRQLDRQNSAQIT----ETFTPKFSTP--------KTPGKE--FQFKFTDPTVQ-----
----------------NNAALIKE---------RLLSWCRAKTKEYENV---QLDNFSTS
WSNGLGFCALIHHFRP---DAFDYHSLRSED---------------------RRKNF---
--------ELAFTKADEVAGIAPLLDVEDMVMMRR-PDWKCVFTYVQSIY-----RRFKD
ED--------------------
>gi|118763658|gb|AAI28650.1|	Xenopus tropicalis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MRKASRSVGAAPKVPANNKSQ-------ATERSKSESSAPT
ASKVS-RPGSSLS--------KAKSNDDLLAGMA--GGLPASNSVKVKKNSTTSYP--NS
GTAMSGQEGRTRSSAGSSSNTKRSGSSGAKEV--GSS--RERL-----RERSRLTANKKP
QGLGVGTGE--VSAPSK-----RSRGRTDSDM-IRMSK----SKSDNQISDRAALEAKVK
ELMNLAKNKDAEILL-LRTELRDTR----------SQLG-------QDVSDKSPDDL---
------------PLIHLQE-----QNTTVCEELQQLKSENRMLKD--RLNALGFSLGQQP
DDPDKLYGFQSLG---INPGSHSDCGG------GTLTSSVEGSAPGS--MEDLLSQDEST
LTGERRSSSMDNLDSECSEVYQPLTSSDDA-----LDAPS---SSSESEG-LPS--TERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTAEELQATLQELADLQQITQELNSENE
RLGEEKVILMDSLCQQSDK-LELFSRQLEYAQALL--DEHHIAYS-LDEDLKS--SRYLD
LEQRYMDLAENGRF-----EREQLLGVQQHLSNSLKMAEQDN------------KDAQDV
IRALK-ERNHHM----------------------ERIAEAEQLSKQALAAT---------
-------------------LEEYKATLNSEQ--------GECARLKA------LLEQEKQ
RVAE--LYSIH----------------SSGDA-SHIQN----LLESVRSDKEKAESLAS-
-------------------------------SLQEELLHARTDVNRM------QDAFG--
------------------KLEDEYRAFREEA----------------QKQ---VSELTL-
-ALEKVRHELEEKETELSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---VENAVKKL-----QDQKHD----MEREIKILNRKLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGELKRQLQEA--LEKNEKLAKE--MENATSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLNRRSSTSSDPA--PTVKTLIK
SFDNASS-QAPSPAAAV--AAAAATPISRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPISVAKSLPGLSEKRPSYAEIPVQ-EHMLRSSSSSRSAASLPRV--------PAIDNA
KSISVSRRSSEELK---RDISVPDGSSAPSLMVMTSPSPQLS--LSS--SSPTASVTPTA
RSRIREERKD------PLAALAREYGGS--KRNALLKWCQKKTEGYPNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELTNQD---------------------KRRNF---
--------TLAFQAAESV-GIKSTLDINEMVRTER-PDWQCLMTYVTSIY-----KYFET
----------------------
>gi|76639657|ref|XP_597976.2|	Bos taurus
MGAESSRGLQLAGRAPLPRELVAENTNVPPQASEEEFHQTPAFFYARLHYVGGPGSGGES
RWPESVPGPHVARARAVCLRLGPEGRCRARLLSGACAPQSPLYLAGLCTALGPAFQRFWF
AAVGFPEEGSDSRTGRISGAQEPPVGSTVPSGGLEGAWSEQLLGLKSRERRPWAECSWGA
EEEGLKLGSKQTTSWPGQRVSPDTILLQRLRSSSADRGVLGGCLATALLLSVPPGPLSCE
TQSVPIRFACKCIAKRQPRMKKASRSVGSAPKVSGTSRVQ-----AADKARPESSSSASA
GSRPV-KPGAAAALS------KTKSSDDLLAGMA--GGVTVTNGVKGKKNACSSAAPAAP
APAVSATENRPRTGTGTSSSTKRSTCTGNKEP--SST--RERL-----RERTRLNQSKKL
PSAGQGAN---DVASAK-----RSRSRTAAECDVRMSK----SKSDNQISDKAALEARVK
DLLTLAKTKDVEILH-LRSELRDMR----------AQLGISEDPLTEGAETSEEKEA---
-STVHQPTDVESTLLQLQE-----QNAAIREELNQLKNENRMLKD--RLNALGFSLEQRL
DHSEKLFGYQSLSPE-ITPGNQSDGG-------GTLTSSVEGSAPGS--VEDLLSQDENT
LMDHQHSNSLDNLDSECSEVYQPLTSSDDA-----LDAPS----SSESEG-LPS--VERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENE
RLGEEKVILMESLCQQSDK-LEHFSRQIEYFRSLL--DEHHISYV-IDEDVKS--GRYME
LEQRYMDLAENSRF-----EREQLLGVQQHLSNTLKMAEQDN------------KEAQEL
IGALK-ERSHHM----------------------ERAVESEQKGKAALAAT---------
-------------------LEELRATLASDQ--------IEMNRLKA------QLENEKQ
KVAE--LYSIH----------------NSGDK-SDIQD----LLESVRLDKEKAETLAS-
-------------------------------SLQEDLAHTRNDANRL------QDAIA--
------------------KVEDEYRAFQGEA----------------KKQ---IEDLNV-
-AVEKLRSELEERDTERSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENTVKKL-----QDQKHD----MEREIKTLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLKRRLHEA--QEKNEKLTKE--LEEIKSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPT--PTVKTLIK
SFDSAS--QVPSPAAAA---------MPRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPISTSKPLTALSDKRPNYGEIPVQ-EHLLRTSSTSRP-ASLPRV--------PAMESA
KTLSVSRRSSEEMK---RDVSAPEGTSPAALMAMGATSPQLS--LS---SSPTASVTPTA
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELNSQD---------------------KRRNF---
--------TLAFQAAESV-GIKSTLDINEMVRTER-PDWQNVMLYVTAIY-----KYFET
----------------------
>gi|11602887|gb|AAF93171.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--MAQVPGEVDNMEGLPAPNNNPAARWESPDR--GWEREQPAASTAAASLFECSRIKALA
DEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLR--DGFVLTRLLEVLSGEQLPRP-TRG
RMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNH--RLTL-----GLVWTIILRFQI
QVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFT--TSWRDGLAFNALIHRHRP
DLVDFSKLTKSNANYNLQRAFRTAE----------QHLGLARLLDPEDVNMEAPDEK-SI
ITYVVSFYHYFSKMKALAV-----EGKRIGKVLDQVLEVGKII-E--RYEELAAELLAWI
HRTVGLISNQKFANS-LSGVQQQLQAFTAY---CTLEKPVKFQEKGN--LEVLLFSIQSK
LRACNRRLFVPREGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQR--FDHK
VAMRES----WLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQ
ALAAEGYYDIRRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVY-MVDWME
EMQAQLLSRECGQH---LVEADDLLQKHGLLEGDIAAQSERV------------EALNA-
-AALR----FSQ----------------------PCDPQVICNRVNHVHGC---------
-------------------LAELQEQAARRR--------AELEASRSLWALLQELEEAES
WARD--KERLLEAAGGGGAAGAAGAAGTAGGA-HDLSS----TARLLAQHKILQGELGGR
RASLQQALRCGEELVAAGGAVGPGADTVHLVGLAERAASARRRWQRL------EEAAARR
ERRL--------------QEARALHQFGADL----------------DGLLDWLRDAYR-
-LAAAGDFGHDEASSRRLA--------------RQHR--ALTGEVEAHRG----------
------------------------------------------------------------
----------------------------------PVSGLR-----------RQLATLGGA
SGAGPLVVA---LQVRVVEA-----EQLFAE----VTEVAALRRQWLRDALA--VYRMF-
---GEVHACELWIGEKEQWLLSMRVPDSLDDVEVV--QHRFESLDQE--MNSLMGRVLDV
NHTVQELVEGGHPSSDEVRSCQDHL-NSRWNRIVELVEQRKEEMSAV-----LLVENHVL
EVAEVR--AQVREKRRA---------VESAPRAGGAL----------------QWR----
--LSGLEAALQALEPRQAALLEEA---ALLAERFPAQAA-RLHQGAEELGAEWGALASAA
QACGEAVAAAGRLQRFLHDLDAFLDWLVRAQEAAGGSEGPLP--NSLEEADALLARHAAL
KEEVDQREEDYARIVAASEALLAADGAELGPGLALDEWLPHLELGWH-----KLLGLWKA
RRKALVQAHIYQLFLR---DLRQALVVLRNQEMALSGAELPGTVESVEEALKQHRDFLTT
MELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAVTR-LLEKCLIIHPALLHPPWEPPYLPR
SSS-------------------
>gi|91208271|sp|Q2KN95|CYTSA_TE	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MKKSVRPAASKV--------------SGERGKPEVAGNAAA
GKPAS-KSSTAAPLS------KVKSSDDLLAAMA--GGNPASCNAVSKSKRT-----TSV
GTTASTLDSKPKTASGTTS--KRLASSLSKET--NLT--RDRL------RTSRASANKKQ
SAAGPVGG---DAASGK-----RSRGQTLAESEGRMSK----SKSDGQISDKVALETKVK
DLLGLAKSKDVEILH-LRSELRDMR----------AQLGLGGEEPQEGAVEEEKPH----
-VSAITAADVESTLILLQE-----QNQAIREELNLLKSENRMLKD--RLNALGFSLEQRL
DGSDKLFSYASLSPDLAAGSGQSDGGGT-----GTLASSVEGSAPGS--LEDLLT-----
--GHQHGGSADNLDSESSEVYQAVTSSDDA-----LDAPSGASSSSESEC-APS--RERS
RRGSSG----NASEVSVACLTERIHQMEENQHSTAEELQATLQELADLQQITQELNGENE
RLGEEKVILMDSLCQQSDK-LELYGRQIEYLRSLL--DEHHVSYV-LEEDIKS--GRYME
LEQRYADLAENGRF-----EREQLLGVQQHLSNTLKMAEQDN------------AEAQEM
IGALK-ERNHQM----------------------ERIMESERQGRAAVEAT---------
-------------------LEEYKEVASSDQ--------AELSRCRA------QLEQERQ
RVAE--LYSLH----------------TAGDK-NDICQ----LLEGVRLGKEEAEAKAA-
-------------------------------KLQEGLEQAHGELSHL------RETFS--
------------------KLDREYREFQEQA----------------QQQ---MGEQER-
-ALEKQRLDLQEKETEVAD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------LKLHDN-----------LIIT-----
--------D---LENSVKKL-----QDQKHD----MEREIKILHRRLREESME-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLRRRLQEA--QEKNEKLSKE--LEEVKSR----
----KQDEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPS--PTVKTLIK
SFDSAS--QGPPSSGASVTPTASAAPLPRTPLSPSPM-----KTPPAAAVSPIQRH--SV
SGSMSAAKPLSSLGDKRPTYPDISLPAEHLLRGSAAGRPPSALQRV--------SNMDST
KAISVSRRSSEEMK---RDMAAPDGASSASLMAMSAASSPLA--LAS--SSPTASVTPTT
RSRLREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCAVLHTYLP---AHIPYQELTSQE---------------------KRRNF---
--------TLAFQAAESV-GIKCTLDINEMVHTER-PDWQSVMTYVTAIY-----KYFET
----------------------
>gi|90403584|ref|NP_001035052.1	Pan troglodytes
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MKKASRSVGSVPKVSAISKTQ-----TAEKIKPENSSSAST
GGKLV-KPGTAASLS------KTKSSDDLLAGMA--GGVTVTNGVKGKKSTCPSAAPSAS
APAMTTVENKSKISTGTASSTKRNTSTGNKES--SST--RERL-----RERTRLNQSKKL
PSAGQGAN---DMALAK-----RSRSRTATECDVRMSK----SKSDNQISDRAALEAKVK
DLLTLAKTKDVEILH-LRNELRDMR----------AQLGINEDH-SEGDEKSEKET----
-IMAHQPTDVESTLLQLQE-----QNTAIREELNQLKNENRMLKD--RLNALGFSLEQRL
DNSEKLFGYQSLSPE-ITPGNQSDGG-------GTLTSSVEGSAPGS--VEDLLSQDENT
LMDHQHSNSMDNLDSECSEVYQPLTSSDDA-----LDAPS----SSESEG-IPS--IERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENE
RLGEEKVILMESLCQQSDK-LEHFSRQIEYFRSLL--DEHHISYV-IDEDVKS--GRYME
LEQRYMDLAENARF-----EREQLLGVQQHLSNTLKMAEQDN------------KEAQEM
IGALK-ERSHHM----------------------ERIIESEQKGKAALAAT---------
-------------------LEEYKATVASDQ--------IEMNRLKA------QLENEKQ
KVAE--LYSIH----------------NSGDK-SDIQD----LLESVRLDKEKAETLAS-
-------------------------------SLQEDLAHTRNDANRL------QDAIA--
------------------KVEDEYRAFQEEA----------------KKQ---IEDLNM-
-TLEKLRSDLDEKETERSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENTVKKL-----QDQKHD----MEREIKTLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLKRRLHEA--QEKNEKLTKE--LEEIKSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPT--PTVKTLIK
SFDSAS--QVPNPAAAA---------IPRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPISTSKPLTALSDKRPNYGEIPVQ-EHLLRTSSASRP-ASLPRG--------PAMESA
KTLSVSRRSSEEMK---RDISAQEGASPASLMAMGTTSPQLS--LS---SSPTASVTPTT
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELNSQD---------------------KRRNF---
--------MLAFQAAESV-GIKSTLDINEMVRTER-PDWQNVMLYVTAIY-----KYFET
----------------------
>gi|149720178|ref|XP_001488757.	Equus caballus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MKKTSRSVGSVPKVSGISKTQ-----TVEKTKPENSSSASA
GGKPL-KPGTAASLS------KTKSSDDLLAGMA--GGVTVTNGVKGKKSTCPSTASLAS
APAMTTVESKSKTSTGTSSSAKRSTSTGNKES--SST--RERL-----RERTRLNQSKKL
PSAGQGAN---DVALAK-----RSRSRTATECDVRMSK----SKSDNQISDKAALEAKVK
ELLTLAKTKDVEILH-LRNELRDMR----------AQLGINEDH-SEGDEKSEKEA----
-IIAHQPTDVESTLLQLQE-----QNTAIREELNQLKNENRMLKD--RLNALGFSLEQRL
DNSEKLFGYQSLSPE-ITPGNQSDGG-------GTLTSSVEGSAPGS--VEDLLSQDENT
LMDHQHSNSMDNLDSECSEVYQPLTSSDDA-----LDAPS----SSESEG-IPS--IERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENE
RLGEEKVILMESLCQQSDK-LEHFSRQIEYFRSLL--DEHHISYV-IDEDVKS--GRYME
LEQRYMDLAENARF-----EREQLLGVQQHLSNTLKMAEQDN------------KEAQEM
IGALK-ERNHHM----------------------ERIIESEQKGKAALAGT---------
-------------------LEEFKATVASDQ--------IEMNRLKA------QLENEKQ
KVAE--LYSIH----------------NSGDK-SDIQD----LLESVRLDKEKAETLAS-
-------------------------------SLQEDLAHTRNDANRL------QDTIA--
------------------KVEDEYRAFQEEA----------------KKQ---IEDLNM-
-TLEKLRSELEEKETERSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENTVKKL-----QDQKHD----MEREIKTLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLKRRLHEA--QEKNEKLTKE--LEEIKSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPT--PTVKTLIK
SFDSAS--QVPNPAAAA---------IPRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPISTSKPLTALSDKRPNYGEIPVQ-EHLLRTSSTSRP-ASLPRV--------PAMESA
KSISVSRRSSEEMK---RDISAPEGASPASLMAMGTTSPQLS--LS---SSPTASVTPTT
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELNSQD---------------------KRRNF---
--------TLAFQAAESV-GIKSTLDINEMVRTER-PDWQNVMLYVTAIY-----KYFET
----------------------
>gi|115655406|ref|XP_797893.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------MKLKRKLVDLEIEGTSLPRTSNNSPSYNNNSSNTNSNNSRGLATTQG
FESSI-KPDGAIVLKNHGVREEEEKSSGRTAEVR----------------RADPETKETP
SVPVVDDSRREKEEDKEKLVRGEISDGGQKTP----------------SSSSSASSASSA
SSSSPQTSLALSREPTK-----KDEERIASSLEESVCV----SNGNQDVEDSSNLPEPED
DRDSLEKDSVVSQESSSHTDTESDT---------DRETGQTPKQEKQEESGSEAISE---
-PVLETKEDVEMDA----D-----DEASKCDSIQITKQTKPIP----VVRKVKPEPVASS
SSSSPSSSYSSSSGT-GSSSGSSSEL-------DEVTGQPKGKKRGK--------GLKEA
MRRRAQLKAIELAKESAKEVKEEKKEEPQE--------------TSSQEGSSPV--SEAV
KVEPVK----DEAEL---EKVDRVLE-EDNKNKNNDNLTSRTVENLAVESKLEVKDVEDV
KVSRKKDEDSGTKEEEDAT-EPSSSQSQSSSSSSSSSDESASVKTPSEDKTASS-SQHVD
SISKGKDTLGTVSX---KISMTLHSPVTSTTTFPISNSTSPS------------TSTSEN
ISSVI-EVTPKM----------------------SARVQPTSPSLSNSSDG---------
-------------------LSQKASSPAGDE--------THDGAVLSV----NKTDSSEH
SVDK--PIKSV----------------SSPGT-STTPSIPRNFGHPFRFTKARDDNAIPT
PKKTTTSVRRSE---------------SAVSSLQSKRNKFLNNRPRP------DDNTSPT
SSVPARSFKNVVSGSKFAALRDKFGASNDNS----------------NNN---AGQGKHS
PSSSTPKSLWQQKSPSSSS--------------RYGG--SISEESSLNSS----------
------------------------------------------------------------
----------------------------------PRQNKS-----------IYGT-----
--------P---PSSPLTPLPYMTPPESPSD----LRSKTASPSTPLASSTPTGTAELKS
PTAAELKRQFLFGAD--DSQQGDVFADENSNLKDVS-MAPIEQIEDEAALEKMLEE----
---ATEFDERK-----KIRSRLREV-------RKKKRDDREQKAQAQERA--FEEKMHKL
EVESAQ------QRMRA---------VGLTVQTPGDR-----------------------
SKTVTETKDDGKTKTRVETTMTDSGNSKSVQMTIMSKTEDEGFKAQ--------SIQQES
KSISVGPGGSSSVT-MSKSVSSSSSSTTSTEKPKGRPQNQEAYELKKKQAEDAKNRKAAL
FNKFGGAGGGGGAKPAGGGGTTMKVQNATTIKQKLLEWAQRCTRGYAGV---NVTNFSSS
WCDGMAFCALIHHYYP---DSFDFNTLDPKK---------------------RRKNF---
--------DLAFNTAEEQADIMPLLDTDDMIMMKNAPDWKCVFTYVQSLY-----RHLNK
PTA-------------------
>gi|109093548|ref|XP_001094607.	Macaca mulatta
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MKKASRSVGSVPKVSGISKTQ-----TAEKVKPENSSSAST
GGKLV-KPGTAASLS------KTKSSDDLLAGMA--GGVTVTNGVKGKKSTCPSAAPSAS
APAMTTVESKSKISTGTASSTKRSTSTGNKES--SST--RERL-----RERTRLNQSKKL
PSAGQGAN---DVALAK-----RSRSRTATECDVRMSK----SKSDNQISDRAALEAKVK
DLLTLAKTKDVEILH-LRNELRDMR----------AQLGINEDH-SEGDEKSEKET----
-IMAHQPTDVESTLLQLQE-----QNTAIREELNQLKNENRMLKD--RLNALGFSLEQRL
DNSEKLFGYQSLSPE-ITPGNQSDGG-------GTLTSSVEGSAPGS--VEDLLSQDENT
LMDHQHSNSMDNLDSECSEVYQPLTSSDDA-----LDAPS----SSESEG-IPS--IERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENE
RLGEEKVILMESLCQQSDK-LEHFSRQIEYFRSLL--DEHHISYV-IDEDVKS--GRYME
LEQRYMDLAENARF-----EREQLLGVQQHLSNTLKMAEQDN------------KEAQEM
IGALK-ERSHHM----------------------ERIIESEQKGKAALAAT---------
-------------------LEEYKATVASDQ--------IEMNRLKA------QLENEKQ
KVAE--LYSIH----------------NSGDK-SDIQD----LLESVRLDKEKAETLAS-
-------------------------------SLQEDLAHTRNDANRL------QDAIA--
------------------KVEDEYRAFQEEA----------------KKQ---IEDLNM-
-TLEKLRSDLDEKETERSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENTVKKL-----QDQKHD----MEREIKTLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLKRRLHEA--QEKNEKLTKE--LEEIKSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPT--PTVKTLIK
SFDSAS--QVPNPAAAA---------IPRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPISTSKPLTALSDKRPNYGEIPVQ-EHLLRTSSTSRP-ASLPRV--------PAMESA
KTLSVSRRSSEEMK---RDISAQEGASPASLMAMGTTSPQLS--LS---SSPTASVTPTT
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELNSQD---------------------KRRNF---
--------MLAFQAAESV-GIKSTLDINEMVRTER-PDWQNVMLYVTAIY-----KYFET
----------------------
>gi|60360482|dbj|BAD90485.1|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------CGQAAET
VKMTTTVATDYDNIEIQQQYSDVNNRWDVD----DWDNEN-----SSARLFERSRIKALA
DEREAVQKKTFTKWVNSHLARVSCRITDLYTDLR--DGRMLIKLLEVLSGERLPKP-TKG
RMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNH--RLTL-----GLIWTIILRFQI
QDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFT--TSWRDGMAFNALIHKHRP
DLIDFDKLKKSNAHYNLQNAFNLAE----------QHLGLTKLLDPEDISVDHPDEK-SI
ITYVVTYYHYFSKMKALAV-----EGKRIGKVLDNAIETEKMI-E--KYESLASDLLEWI
EQTIIILNNRKFANS-LVGVQQQLQAFNTY---RTVEKPPKFTEKGN--LEVLLFTIQSK
MRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARR--FDRK
AAMRET----WLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVMAVAR
ELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLY-IMDWMD
EMKVLLLSQDYGKH---LLGVEDLLQKHALVEADIAIQAERV------------RGVNAS
AQKFATDGEGYK----------------------PCDPQVIRDRVAHMEFC---------
-------------------YQELCQLAAERR--------ARLEESRRLWKFFWEMAEEEG
WIRE--KEKIL----------------SSDDYGKDLTS----VMRLLSKHRAFEDEMSGR
SGHFEQAIKEGEDMIAE--------EHFGSEKIRERIIYIREQWANL------EQLSAIR
KKRL--------------EEASLLHQFQADA----------------DDIDAWMLDILK-
-IVSSNDVGHDEYSTQSLV--------------KKHK--DVAEEITNYRP----------
------------------------------------------------------------
----------------------------------TIDTLH-----------EQASALPQA
HAESP---D---VKGRLAGI-----EERCKE----MAELTRLRKQALQDTLA--LYKMF-
---SEADACELWIDEKEQWLNNMQIPEKLEDLEVI--QHRFESLEPE--MNNQASRVAVV
NQIARQLMHNGHPSEKEIRAQQDKL-NTRWSQFRELVDRKKDALLSA-----LSIQNYHL
ECNETK--SWIREKTKV---------IESTQDLGNDL----------AGVMALQRK----
--LTGMERDLVAIEAKLSDLQKEA---EKLESEHPDQAQ-AILSRLAEISDVWEEMKTTL
KNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNT--LTE--AEKLLTQHENI
KNEIDNYEEDYQKMRDMGEMVTQGQTDA--QYMFLRQRLQALDTGWN-----ELHKMWEN
RQNLLSQSHAYQQFLR---DTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDF---
--------MTTMDANEE--KINAVVETGRRLVSDGNINSDRIQEKVDSID-----DRHRK
NREAASELLMRLKDNRDLQKFL
>gi|114326347|ref|NP_001041579.	Canis lupus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MKKASRSVGSVPKVSGISKTQ-----TVEKTKPENSSSAST
GGKVI-KTGTTASLS------KTKSSDDLLAGMA--GGVTVTNGVKGKKSTCPSTGSSAS
APAMTTVENKSKISTGTSSSTKRSTSIGNKES--SST--RERL-----RERTRLNQSKKL
PSAGQGAN---DVALAK-----RSRSRTTTECDVRMSK----SKSDNQISDKAALEAKVK
DLLTLAKTKDVEILH-LRNELRDMR----------AQLGINEDH-SEGDEKSEKEA----
-IIAHQPTDVESTLLQLQE-----QNTAIREELNQLKNENRMLKD--RLNALGFSLEQRL
DNSEKLFGYQSLSPE-ITPGNQSDGG-------GTLTSSVEGSAPGS--VEDLLSQDENT
LMDHQHSNSMDNLDSECSEVYQPLTSSDDA-----LDAPS----SSESEG-IPS--IERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENE
RLGEEKVILMESLCQQSDK-LEHFSRQIEYFRSLL--DEHHISYV-IDEDVKS--GRYME
LEQRYMDLAENARF-----EREQLLGVQQHLSNTLKMAEQDN------------KEAQEM
IGALK-ERNHHM----------------------ERIIESEQKGKAALAAT---------
-------------------LEEYKATVASDQ--------IEMNRLKA------QLENEKQ
KVAE--LYSIH----------------NSGDK-SDIQD----LLESVRLDKEKAETLAS-
-------------------------------SLQEDLAHTRNDANRL------QDTIA--
------------------KVEDEYRAFQEEA----------------KKQ---IEELNM-
-TLEKLRSELEEKETERSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENTVKKL-----QDQKHD----MEREIKTLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLKRRLHEA--QEKNEKLTKE--LEEIKSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPT--PTVKTLIK
SFDSAS--QVPNPTAAA---------IPRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPISTSKPLTALSDKRPNYGEIPVQ-EHLLRTSSTSRP-ASLPRV--------PAMESA
KTISVSRRSSEEMK---RDISAPEGASPASLMAMGTTSPQLS--LS---SSPTASVTPTT
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELNSQD---------------------KRRNF---
--------TLAFQAAESV-GIKSTLDINEMVRTER-PDWQSVMLYVTAIY-----KYFET
----------------------
>gi|110755090|ref|XP_397297.3|	Apis mellifera
------------------------------------------------------------
------------------------------------------------------------
-----------------MAPPPPPAPPTTTITTGTKSLVAERLFLAQSPVRVGPQYTDTA
PLTLQGGRLKIRRIKMSEAEDNQSVVENHDFQSIIEGESRRSNSVHYLNTHENISKETVK
EYSEEAKEELYQEKKEKEIFVENERKSNEAEKKEGTQAAGSSTGTVDDNDKGVSRLEENA
TRKEEATNTSTTTGTTIDGRNAPVGEWNSLPHLVDRLRAALELSLGSRRDDEPPAV-LED
SGIDSEEDFRMRNSME-----QALGNCKEPELKKDLKFLEDLLLSDIQTALSRLRETLEK
IDVAALAKHGAASDPTSKLQLLRLVSSLLSRLQVPEEK----TKEKIPSVLPSTSLSRRR
RGTRHTIGVSTEELAKARKWLEEEK----------NILPLEDITLVTKEQKEQNVP--GN
GVNVINMIDKKSEEIRDKCTKDAINQRQLLEDKNKEIRDNCVFREIQQVDVADSKSNRDL
NMYQTQYRVNNYQEK-ENNE-------------NDVVEDSEEKSRVSKLASILKQRAELS
ASGSGKYGGANKFSAKKSKIKRANT----------IDIPSYLKLQAESLGHETAGCVSLR
KPINVG----DKTTF---NSVNVIVPTFQPKTENDRKFLALINKNNEVPPVS---SVPFK
TIGQ--TMDMSSLTNENWN-SRFSNIKTAFDKSTTATDEREIKPSLKFRANKM----FPN
SPQTQIYSNTNPNYDPRMTKTDATTGFRHAPSSPFRKIEKSGSPSNVPLSYHWPKNIPMP
TSTLK-EKARMMFDRETTQPSSKSSRNYPEKSSFTRSPWIEHENKSNGTVTENGKLDYRS
FCKQFAPFVGKTFSNESKKLEEQQELIQRDRLPGIVDGKISFKVVPDKRVQTYQYPSMER
RVSKEKLEIIKSGKEHEYDEDSFADAILRGSSSVAVQT----GIDEDHQNEERSFRVAPK
ISKNQNLICSNVAVQTS--------SELNKPVISVNDMDTRKQWTPLCYEQSDSDQTSED
RQRFVL------------DHNQNYHTVSSDSEFNSPVVIPDVNEQSFKEIVPFLGTQSYQ
KSTENPVKNYQTENTNNQDYSSSLISPILSDYNQSDEILNAREECENHKKTDWPVESSNF
PNDQNIQNQDISPEIGVVTRYTCAIGTVASSVDSPEPRSEEIAVDSRASSSPSPSQWSWT
RSRPPTNETIASEDEIRRHNLLQQSLVRRLQNEITSLNDQ-----------PQISNFGQH
LTI-----N---QKSQSPNL-----GQSYQQKFSNQSMNFATTHQQQNHNQPINVSQ---
---KNIPFQQSNFNKSIHTIHQEQTFNQSVNFDRSSNSQKPNRFIKY--LTPVPQK----
KPETSRVHSPGPVIVNRVGALREAY-EQTPNSQTKSIHKERSPVPNGMAPN-DSSDEYLV
SCATKPSRSIVLSKSESWHQLAISNRYPRTSRVNAPASLSSFPKPPKPRSPSSQKLRSKQ
FEASSMADSVKKMEDKIRQYFDQP---SDIIETKDSIKH-RRSPRFATK-----GMLELS
RSRTMPGLSEEKLH-----VLIP-TPQQMPLLNVNTADVDKV--FDDLFEEATRTDNHPV
KSPATEFRFK------FTEPTVRDNAVQ--IKERLLAWCRSKTKEYENV---QLDNFSTS
WNNGLAFCALLHHFRP---DAFDFYSLQPEN---------------------RRMNF---
--------ELAFKKADELAGIAPLLDVEDMVMMRR-PDWKCVFTYVQSIY-----RRFKD
ED--------------------
>gi|149641754|ref|XP_001509479.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-------------------MKSAAKPWGTVAKQGSHGTDR-------GRPLPAASSGMKT
S-----KSSTSLAFESRLSKLKRASSDDMLTK----PGVTTASGVARIKKT------ATT
GAISELAEGRLKSNTGTVSSSKRTGIPAPREL--SATISRERA-----VLRSSPSTRKSV
PSPTSSGT----PTPTK-----HLKSSAK-------------PKQENEAGDKAVLESQIR
ELLAEAKTKDFEISK-LQSELQKCK-------------ELPTADISGGASDQNVDGL---
---AGPLGDMDPLIRALQE-----KNRTFQKELASLGEENRALKE--KL----IYLEQSP
VSETTTSNCGESSLQ-TPTTQE-----------SSFGSPTKSQLPGE----------SDE
YQQHVNGNSLQTPGSSSSDVTKASLSPDASDFEHIVEAPSRPVSSSSNP-------FKSS
RCSTSGSSPNNISELSVASLTERIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENE
KLVDEKALLETSFHQQRER-AEQLSQENEKLMNLL--QERSKN-----EEARSQDEKVLE
LEHKCTEILEKAQF-----EREKLLNIQQQLTCSLRKVEGEN------------QGALEM
IKCLK-GENEQL----------------------SGFLELERQNTSLTVKS---------
-------------------LEECRVDLEGLK--------IENGSLRA------QLDSEKQ
KAAE--INALG----------------NSADS-SEVHE----MLRVARAEKDQLELSCT-
-------------------------------ELKQELLKAKSEIKQV------QGLLT--
------------------KVEKECSHLRELS----------------DRQ---TEQLSR-
-TSLKLQEKASESDAEIKD--------------MKETIYELEDQVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHNN-----------QLIS-----
--------E---LESSVMKL-----EEQKLD----LERQLKTMSKQIKEETEE-WRRFQ-
---ADLQTAVVVAND-IKCEAQQELRTVKRKLLEE--EEKNAKLQRE--LEEVQGS----
----NRLVVSR-----PVNEEAEFS-ETDASSRWQGVCVSRASPTPSESA--ATVKSLIK
SFDLAG--TGQNIPAHK---------APRSPLSGIPV-----RTAPAAAVSPMQRH----
-STYSNAKPASKVIAKLGALPDLPLT-DILKGRNEDLKPDHYLRKS--------PSLESL
SRPASLGFSNTRML-----------------------------------TPTLGGVKP--
QSKLSVERKD------PLAALAREYGGS--KRNALLKWCQKKTEGYPNI---DITNFSSS
WSDGLAFCALLHTYLP---AHIPYQELNGQE---------------------KKRNL---
--------LLAFQAAESV-GIKPSLELSEMMYTDR-PDWQSVMQYVAQIY-----KYFET
----------------------
>gi|125847620|ref|XP_683059.2|	Danio rerio
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------MCSPRK
ITSAGVRLRCKCIKNLEPSMKKATKPTAATSRTSVGTK---------APGRSEGSSNMGT
GGKMTNKTQSSAPLS------KAKSSDDLPAVSAGSGSVSASNSNTTARNKR-----GSS
SQITSNTETRSKTTSGLSG--RRATSTVSKEP--GLT--RDNL-----RERSRTSVAKKP
T----------DTMPQK-----RSRCRTLPDSESKMSK----SRSDSQISHKAVLECQVN
DLLGLAKSKDLEILH-LRSELRGMR----------TQLGLEELEAPNQEQVSQETMQ-PP
EKEVISATDVESTLLLLQD-----QNQGILDELNMLKSENRMLKD--RLNALGFSLEQRL
DSPEKSLRCLPMSPEHVVGGDSSSGGHSESVRGGMRASSAEGSAQGS--TEDLLSE----
---QRHLGSPDAVDSECSEAYQPITSSDDA-----LDAPSGCGSSSESEGGLPS--REHS
RRGSSG----NTSEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELSTENE
RLGEERAILVDSLCQQGER-LELYGRQLEYFRGLL--DEHCVAYVKDDEDAKS--GRYVE
LERRYAELNEGSRF-----EREQLLGVQQQLSSALKMAEHEN------------AEAQGL
MAALK-ERVIMA----------------------ERAVEIERRERAVAKAE---------
-------------------LEALRVLSEGEQ--------VELNRCRI------QLEQERQ
RVAQ--LLSIH----------------NAGDK-TDIRH----LLESERLDKERAEAKAA-
-------------------------------QLKEELGHTRSEAAQL------QEAIS--
------------------KLEDEFRAFRDDV----------------QSQ---LAEQKR-
-LLEQQCSELEEKDTEIAD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENSIKKL-----HDQKYD----MEKEIKVLHRKLREESAE-WRQFQ-
---ADLQTAVIIAND-IKTEAQEEIGDLRRRLQEA--QEKNEKMNKE--LEELKSR----
----KQDEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPS--PTVKTLIK
SFDSAS--QGSPTAAAA--AVAAATAISRTPLSPSPV-----KTPPAAAVSPIQRH----
--TISSSKPLSSMLDKRPSFNDLNIPAEHLLRTSPVTRPGCPIQRV--------TNMDTS
KAISVSRRSSEELK---RDLLAPESSAPSSLM----SSPQLS--LSSNASSPTASITPTT
RGRLREERKD------PLSALAREYGGS--KRNALLRWCQKKTEGYQNI---DITNFSSS
WNDGLAFCAILHTYLP---AHIPYHELNSLD---------------------KRRNF---
--------TLAFQAAESV-GIKSTLDIGEMVHTER-PDWQSVMTYVTSIY-----KYFET
----------------------
>gi|73963241|ref|XP_866290.1|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSS-------ARLFERSRIKALA
DEREVVQKKTFTKWVNSNLARVPCRITDLYKDLR--DGRMLIKLLEVLSGEILPKP-TKG
KMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNH--RLVL-----GLIWTIILRFQI
QDIIVQTQEGRETRSAKDALLLWCQMKTAGYPQVNVTNFT--SSWKDGLAFNALIHKHRP
DLIDFDKLKDSNARHNLEHAFDVAE----------RQLGIIPLLDPEDVFTENPDEK-SI
ITYVVAFYHYFSKMKVLAV-----EGKRVGKVIDHAIETEKMIE---KYSGLASDLLTWI
EQTIVVLNSRKFANS-LTGVQQQLQAFSTY---RTVEKPPKFQEKGN--LEVLLFTIQSR
MRANNQKVYTPHDGKLVSDINRAWESLEEAEYQRELALRHELIRQEKLEQLARR--FDRK
AAMRET----WLNENQRLVVQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVKALEDLAQ
ELEKENYHDQKRITARKDNILRLWNYLQELLRTRRQRLEMTLALQKLFQDMLH-SIDWMD
EIKAHLLSAEFGKH---LLEVEDLLQKHKLMEADIAIQGDKV------------KAITAA
TRQFA-EEKGYQ----------------------PCDPQVIQDRVSHLEQC---------
-------------------FEELSNMAAGRK--------AQVEQSKRLWKFFWEMDEAES
WIKE--KEQIY----------------SSLDYGKDLTS----VLILQRKHKAFEDELRGL
DTHLGQIFQEAEGMVAR--------KQFGYPQIEVRIKEVSAQWDQL------KELAAFR
KKNL--------------QDAENFFQFQGDA----------------DDLKAWLQDAHR-
-LLSGEDVGQDEGATRALG--------------KKHK--DFLEELEESRG----------
------------------------------------------------------------
----------------------------------VMEHLE-----------QQAQGFPQE
FRDSP---D---VTNRLQAL-----QELYQQ----VVAQADLRRQRLQDALD--LYTVF-
---GETDACELWMGEKEKWLAQMQIPDTLEDLEVA--QHRFDILDQE--MKTLMTQIDGV
NLAANSLVDSGHPRSGEVKQYQDHL-NARWQAFQTIVSDRRGAVNSA-----LRVRNYCV
DCEETS--KWIEDKMQV---------VQSIKDLGQDL----------TGIISIQRK----
--LSGLERDVAAIEARVGALERES---QQLMASHPEQKE-DIGQRQACVEKLWQELQEAL
KEQEASLGEASQLQAFLQHLDNFQTWLSMAQKAVASEDMPES--LPE--AEQLLQQHVAI
KDEIDGHRGDYQQVKASGENVIRDQTDP--EYLLLGQRLEGLDSGWD-----ALCRMWES
RNHSLAQCLGFQEFQR---DAKQAEAILSNQ---------------------VGR-----
-------------------GIQG-------------------------------------
----------------------
>gi|126344586|ref|XP_001379321.	Monodelphis domestica
------------------------------------------------------------
------------------------------------------------------------
--------------------------------------------------MRQGPGVYQL
SPETHARDLGSGRVRKSVVASVQVTPPSRWRRVPAGPRACAPASLQARRAPLASRPPSPA
GLGLRSEARRPCISARPPRMKKASRTSVSAPKVPAAAKSK---------------PDSPT
GARLS-RPGSAPLA-------KAKSNDDLLAGMA--GGAPGANSMKGKK-TCPVTASTSS
LSVASASDSKTKTGPGTIS--KRNPSVGSRDL--GSSCSRERL-----RERSRPSLGRRV
PAAGQNPG-DPTAASTK-----RSRSRGGRDTDVRMSK----SKSDNQISDRVALETRVQ
ELLRLAQAKEEEIVH-LRDQLHALR----------LRLGLPEEEPPEAVLPPDRDAD---
----------------------------VRQKLGRLKSENRMLRD--RLDALGFSPDD--
---------GPLPMV-AVAGGSPGDG-------GVLGSSTEGSALGS--LEDLLNPDEPA
P----------------------------------MDTPG-----SGEEGPGP---WRSP
SPPTEA-------VSAVACLTERLQQMEENQHSTSEELQATLQELADLQQISQELGGENE
RLGEERLLLLQSLGQQSER-LELLGRQVEYLRSLL--DEHHVAYV-LDEDVRS--GRYLE
LEQRFLELAENARF-----EREQLLGVQQHLSAALHLAEQDA------------QDGQEL
IRALK-ERNLHM----------------------ERALEAEQKNAASLAAA---------
-------------------LEQQQATVASDQ--------LELGRLRT------QLESEKQ
RVAE--LYSLH----------------SAGDK-SDIQD----LLDSVRQEKDKAEALAG-
-------------------------------SLQEDLTHARADVTRL------QDTIT--
------------------KIQDESRGFQEEA----------------QKK---MGELNV-
-QLEKLRSELEEKETERGD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LVIS-----
--------D---LENTVKKL-----QDQKHD----MDREVKTLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEVGDLKRRLQEA--QEKNEKLSKE--LDEVKSR----
----KQEEERG-----RVYNYMNTV-ERDLAALRQGMGLGRSSSASSEPA--PTVKTLIN
SFDSASSPQAPSGCSVL-----PGGPGRRGPRSTAGETEAGHKHPGLGVHSGLSDSPPAI
SPSWRPECPLWGLGEPQRVHRFEPGG-----PRVPAGRGTSPLGQLFM------PAASSS
PPSAPPRRSSEDVK---RDMTASDGPSTASLMAMGPSSPQLA--H----PSPTASVTPTA
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELSGLD---------------------KKRNF---
--------SLAFQAAESV-GIKSTLNISEMARTER-PDWQSVMQYVTAIY-----KYFET
----------------------
>gi|49274627|ref|NP_700455.2|	Mus musculus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---MTISENKSKISTGTSSSAKRSTSAGNKES--SST--RERL-----RERTRLNQSKKL
PSVSQGAN---DVALAK-----RSRSRTAAEGDIRMSK----SKSDNQISDKAALEAKVK
DLLTLAKTKDVEILH-LRNELRDMR----------AQLGISEDH-CEGEDRSEVKET---
-IIAHQPTDVESTLLQLQE-----QNTAIREELNQLKNENRMLKD--RLNALGFSLEQRL
DNSEKLFGYQSLSPE-ITPGNQSDGG-------GTLTSSVEGSAPGS--VEDLLSQDENT
LMDHQHSNSMDNLDSECSEVYQPLTSSDDA-----LDAPS----SSESEG-VPS--IERS
RKGSSG----NASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENE
RLGEEKVILMESLCQQSDK-LEHFGRQIEYFRSLL--DEHHISYV-IDEDVKS--GRYME
LEQRYMDLAENARF-----EREQLLGVQQHLSNTLKMAEQDN------------KEAQEM
IGALK-ERSHHM----------------------ERIIESEQKGKAALAAT---------
-------------------LEEYKATVASDQ--------IEMNRLKA------QLENEKQ
KVAE--LYSIH----------------NSGDK-SDIQD----LLESVRLDKEKAETLAS-
-------------------------------SLQEDLAHTRNDANRL------QDTIA--
------------------KVEDEYRAFQEEA----------------KKQ---IEDLNM-
-TLEKLRSELEEKDTERSD--------------MKETIFELEDEVEQHRA----------
------------------------------------------------------------
----------------------------------VKLHDN-----------LIIS-----
--------D---LENTVKKL-----QDQKHD----MEREIKTLHRRLREESAE-WRQFQ-
---ADLQTAVVIAND-IKSEAQEEIGDLKRRLHEA--QEKNEKLTKE--LEEIKSR----
----KQEEERG-----RVYNYMNAV-ERDLAALRQGMGLSRRSSTSSEPT--PTVKTLIK
SFDSAS--QVPNAAAAA---------IPRTPLSPSPM-----KTPPAAAVSPMQRH--SI
SGPISTSKPLTALSDKRSNYGELPVQ-EHLLRTSSTSRP-ASLPRV--------PAMESA
KTISVSRRSSEEMK---RDISASEGASPASLMAMGTTSPQLS--LS---SSPTASVTPST
RSRIREERKD------PLSALAREYGGS--KRNALLKWCQKKTEGYQNI---DITNFSSS
WNDGLAFCALLHTYLP---AHIPYQELNSQD---------------------KKRNF---
--------TLAFQAAESV-GIKSTLDINEMARTER-PDWQNVMLYVTAIY-----KYFET
----------------------
