>gi|6323962|ref|NP_014033.1|	Saccharomyces cerevisiae
------------------------------------------------------------
----MSSEDELGSIGTVFPGSPIDKSIGSI------LPQFD-------------EEVETL
LEDSFTWNIPDWNELTNPKYNSPRFRIGDFEWDILLFPQGN-HNKGVAVYLEPHPEEKLD
ETTGEMVPV--------------DPDWYCCAQFAIGISRPGNGDTINLINKSHHRFNALD
TDWGFANLIDLNNLKHPSKGRPLSFLN-----EGTLNITAYVRILKD-PTGV-----LW-
-HNFLNYDS---KKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPT--------
-EHES-PNNSVPLALQRAFYQLQVSD-IPLDTLELTRSFGWDTAES----FTQHDVQELN
RILMDRLENNMKGTPVEGKLNEIFVGKMKSYIK--CINVDYESARVEDFWDLQLNVKNF-
-----KNLQESFDN-YIEMELMNGENQY-AAQDYGLQDAQKGVIFESFPPVLHLQLKRFE
YDFNYDQMVKVNDKYEFPETIDLSPFVDK-------------------------------
-------DVLKKTLDSENKDK---------------------------------------
-------------------NPYVYNLHGVLVHSGDISTGHYYTLIKPGVE---------D
QWYRFDDERVWRV----TKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLV
YIRQEQEEDLLRPVLESD----VPKHVITRVREEIKERETKEKEIREAHLYVTLRLH---
-------SIKEFI----HYEGFDYF-AHDGFRLFAEEL-----NDSGLQQIN--------
------LKVLRTTKLSDIFASIKETMNIPQER-----------DVKY----WKMDYRRNS
TLRLTQPINFESVNITLQEALKKEKKRTMQTQYGEEGVASTEEDDKALLETVSFLD----
---LFIEEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPELTKGGIEPVFATDNKS
NLLFVKSYDPHTQKLLGFGHFAVNQL------------QQLSDISAIIEDSISSNEKLT-
-FYEEVQPGTINEI----------------------------------------------
--YMKETIYDADIDT----------GDIVSFEVPGAVLPDTFPV----------------
---------------------YATIKDFYSYLRYRVKLKFSKFDGSSEEYG---------
------------------------------------------------------------
-------VSNEIPESFEFWISAYAPYDDLARMVSKYA--HVKPEYLKIIALYSNGR----
----FVLKSTSLLNDYLLKD-----FNCDQIPP--FAFEVLSVPL-----------KEL-
---------ERLRPIKLY---------W-----------LKNSYIHYQCFEFEVANDYTE
SQFLEKVQH---------KIGFTDEEKENILLWTNTNFQFQGLLSDQNTFK---DVSKHS
LLFGRILPEESKLFKELNRLENVQTSSLEDFMDDENATDRPMDDEQDLGMAIEHSEDMKG
RIVVVQQYFKDLENRHGISFLFNLIPD--E------TFPKTKDRLHAKFGLG-QKEFS--
-------KIKL-SIGYSTEEGTVF--RSLQGFSDEELDKVILYDIMSNLDYIYMDHPDRL
RSHSSY---DRPMIIKN----------------------------
>gi|73994162|ref|XP_543294.2|	Canis familiaris
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-----------------------MPYFFLRALLSFTMFGDLFEEDYSTVSDYQ-------
----------YGREKKLKTKGLEPPAP---------------------------------
------------REFTNLSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSFED
KDKPDAKVRIIPLQLQRLFAQLLLLDQDAASTADLTDSFGWTSNEE----MRQHDVQELN
RILFSALETSLVGTSGHDLINRLYHGTVVNQVV--CKECKNVSEKQEDFLDLTVAVKNV-
-----SSLEDALWNMYVEEEVFDCDNLYHCGTCDKLVKAAKSAKLRKLPPFLTVSLLRFN
FDFVKRERYKETSCYTFPLRINFKPF----------------------------------
------------CEQSDTDDL---------------------------------------
--------------------EYVYELFSVIIHKGGCYGGHYHVYIKDVDHL--------G
NWQFQEEKSKPG-----MNLKDLQNEEEID--------DDPLIILKAILLQE----SNLI
--PVDQLGQKLLKKIGMS----WNKKYRKQYGPLRKFLQLHSQIFLLSPDESTVSLL---
-------KNGSLQ----AESHFPRS-DQHIFKTLTSES-----PGLNDGTSC--------
-P--HWFDINDSKVQPIKEKDIERQFQGKESA------------YMLFYRKSQLQ-RPPE
ARANPRYGVPCHLLNEMD-----------AANIELQTKRAECDSIDNNFDLHLHLGPHYH
FLNGALHPVVSQAESTWDLTFDKRKTLGDLRQSIFQL-LEFWEGDMVLSVAKLV---PAG
LHVYQML-DGDDLTLCELEIADGEDLFVWNGVEVGGIQIPTGSDCEPLLLNVLH------
-LATSSEGGKCQQLVESPHVFPSNAEVGAVLTALAVPVGVLFINT--TDPAGEENWVAIP
KEDLKKTFREQGLRD----------RSSVLVQDSSDDNSLLLKQGKWFTGMNEVNWLQVQ
NL-----------CELGSEEKQVKISATVNTVVFDIRIKAIKELKLMKELAENSCLRP--
-------------IDRNGKLLCPVPDSYTLKEAELKMGSSLGLCPGKAPTSSQLFLFFTV
G------SDVQPGTEMEIIVEETMSVRDCLQLMLGKS--GLPGDRWHLRKMDWCYEAGE-
----PLCEEDATLRELMICSGDTLLLIEGKLPP--PGFLKVPLWWYQPGG------SPG-
---------HWKNHQDQRNGAPSPGGVWRAAATQGAPGDLHGEVSLRYLGDLEISEEATV
AELKSQAMTLFS------SSGFVIPSPAFLRAWTVERKRLGRLLRINRQQLRDYKLGRKT
EICLEPLQEE-------ENL---GPQDVVLRTRMRLPGERAYAPCVDLVW------DTA-
RGWTAGSLRQRVAHFCSLPVEKIEIAK---------YFPEKFEWLPIS---SWNQQFTKR
KKKKKQDNLQG-APYYL-KDGDTIGIKNVLLEDDGDFSTDA--DDLGRGTPRRPSSPRVS
RSQDALRERSRDLGCGA-TTPG---RPRAPEASLSIHVRSFR---
>gi|70985024|ref|XP_748018.1|	Aspergillus fumigatus
---------------------------------MDNVADNEMLVDEYEQYHNDR------
----TDDVVVSRSGSEEPEPEPLADDFTAM---MARILPKD-------------PDLETA
DEAYHTWHIQDWRKLK-KKEHGPIFQCGGFPWRVLFFPYGN-HVDYASFYLEHAWEKEP-
-----------------------PENWYACVQFALVLW-NVNDPSIYVSHVATHRFNADE
GDWGFTRFCELRRLFNMPWEGRGVPLV----QNDEAKITAYVRVVKD-PTGV-----LW-
-HSFQNYDS---KKETGMVGLKNQGATCYLNSLLQSLYFTNAFRKAVYQIPT--------
-EAEA-TRDNSAWTLQRLFYNLQTSE-SSVSTTELTASFGWESRQI----FEQQDVQELS
RKLMERLEEKMKATPVEKALPGLFVGKTKTYIS--CINVDYESSRVEDFWDIQLNVRGN-
-----KTLDDSFKD-YIQVETLEGENKYDAGSPYGLQDAKKGVIFESFPPVLHLHLKRFE
YDINRDAMMKINDRHAFPMEFDATPYL---------------------------------
------------SDAADKSEP---------------------------------------
---------------------WIYQLHGVLVHSGDLNAGHYYAFLKPTKD---------G
HWFKFDDDRVTRA----TDKEVLEENYGGEYELSNGAAGVRQPHTRGLSTKRSMNAYMLV
YIRKTRLDDVLLPITKDD----IPSHIEKRLVEERAELLRRKKEREEAHLYINVGVL---
-------SDESYT----SHHGFDLT-SADLP---------------AGDPAL--------
-P--KQYRILRAKKVGEFVEQLAEERGLNANQ------------IRL----WVMVNRQNK
TTRPDQAIKDPEMTVEEA-----------YSRFGTKGNP-----------FKVWME----
-----------------------------VGQPSADG-TISWPDS------------STS
VLVFLKNFDVPSQTLSGVGTVYVRKN------------QKVAELAPTILEKMNWPAGTEF
MLFEEIKHNMIDVM----------------------------------------------
--KPKQTFQQSEIQD----------GDIITFQRTVKESDLPSTAL---------------
---------------------YTEARQYYDYLLNRINITFAPIKATDGD-----------
------------------------------------------------------------
--------------EFTLTLSRKMTYDQFSKKVGEHL--NVESTHLRFAPVLASTGKPKQ
FIKRNPNQANQTLYHILSGQVSGYGYSMHRQDA--LYYEVLETSL-----------SDY-
---------ESKTTLKVT---------L-----------LTEGIVKEQLFEVLVPRDGTF
ADLLAGLQK---------KANLEDDVVREMRIFEA---HSGKIYKEYQEDAKIAGINEYV
TLYAERIPEE------------------------------------ELQM------QAGE
RTINAFNFDREPSRPHGIPFKFVMKPG--E------IFKETKERLSKRTGIK-GKQFE--
-------KIKF-AVVPKSLYSNPRY-----LDDDDILSDIV----GESDDMLGLDH--VN
KSRSFWSRSESFFIR------------------------------
>gi|80478768|gb|AAI08426.1|	Mus musculus
-----------------------------------------MVPGEENQLVPKE------
----DVFWRCRQNIFDEMKKKFLQIENAAE---EPRVLCII-------------QDTTNS
KTVSERITLNLPASTPVRKLFEDVANKVGYINGTFDLTRENGVTTADMAPLDHTSDKSL-
-----------------------LDANFEPGKKNFLHLTDKDGEPPQMLLEDS-------
-----------NNVDDSVHDRFIGPLP---------------REGSVASTND-----YV-
-SQNYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-DSEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINELYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SSQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMSFPEELDMSTFIDI-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFST----------DDA----VDEGICLE
SSSG----SEKISKPGLEKNSLMYELFSVMVHSGSAAGGHYYACIKSFSD---------D
QWYSFNDQHVSR-----ITQEDIKKTHGGS--------SGSRGYYSSAFA-SSTNAYMLI
YGLKDPTRNAK-FLEVDE----YPEHIKNLVQKERELEEQEKRQREIERNTCKIKLF---
-------CLHPVKQVMMENKLEVHK-DKTLKEAVEMAY-----KMMDLEDVI--------
-P----LDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRKPD
QI--FQSYKPGEVMVKVH-----------VVDLKAETVAAPVT-------VRAYLN----
------------------------QTVTEFKQLISKA-THLPADSMRIVLERCY---NDL
RLL-----SMPSKTLKAEGFFRSNKVFVESSETVDHQAAFTDSHLWKLLDRHANTIRLFV
-LLPEQSPGSYSKRTAYQKAGGDSGNVDDDCERVKGPAGNLKSVD--------AILEEST
EKLKSLSLQQQQQDG--------DNGDSSKSTETSDFENIESPLNERGSSTSVDNRELEQ
HI-----------QTSDPEN-FQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADS
AQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGDMQYMYFKA
DPYTADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFV--GVLSSHFKVFRVYTSNQEF--
----ETVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVCQL---------L-----------VNEQEPCKFLLDAVFAKGMTV
RQSKEELIPQLR------EQCGLDLSTDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNW
EVFLEVLDGV-------EKMK--SMSQLAILTRRWRPAEMKLDPFQELVL------ESN-
---SVDELREKLSEISGIPLEDIEFAKGRG------TFPCDISVLDIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDRTEEVMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDVAQD----------
>gi|91079889|ref|XP_968047.1|	Tribolium castaneum
------------------------------------------------------------
-----MRRKCEEVSGSSADYGPMSTEDVQV-------------------------DVKYS
DDLGNKTPKQLLLNSTTTVSSIEMFVRDEFPNDHESLDLVLQYEDGKEICLSDHKTSCMA
-----------------------DLGITLTPGHNYTILVSPSEKRNMSLYVND--VTEDD
LLLGASASPTTGEVLSSSASDSAAPID-------DYPEHGHCSRCRIGPTGE--------
-ESSNNVEAMSVVETTNYVGLVNQAMTCYLNSLVQALFMTPEFRNAIYNWEF--------
-DGQN-EARSIPYQLQKLFLNLQTSTRSAVETTDLTTSFGWQGSEA----WHQHDIQELC
RVMFDALERKFKDTKQANLINDLYEGTMLDYVK--CLECGTEKSREDTFLDIPLPVRPFG
STVAYNSVEEALRA-FVQPETLEGNNQYHCEKCNKKCDAHKGLKFIKFPYLLTLHLKRFD
FDYNTMHRIKLNDKVVFPEKLNLNSFVPN---------------------------NRSE
NDGLEERDTVVRCDECSTTDSGSALDDESCQ--GT----------DLSSTVNDHDDNCED
SDEGIDVSSGNAHHENDAKGPYIYELFSIMIHSGSASGGHYYAYIKDFDK---------N
QWLCFNDQSVNR-----ITEEDIKKTYGG---------GPQKGYYSGVYT-SSTNAYMLM
YRQIDKDRNCG-AMKVEE----FPPHMQKLLQNMRNKEKTDRLNKEKQNNSFRLTVN---
-------CYHPYTEEMMDVRISLYL-DSTLEDAVQMAH-----RRFKLEGIV--------
-N----VDDCRMVIFNKKQSCIDCSFESDDLK-----FCDIDDNYKVCYQEWLLDIREPG
TE--FTTYKKGGVNKRTY-----------YVNIETEDVREPFM-------VRIDVG----
------------------------DTVGDVKNKIAEQ-LETNVNNIKVAIAKFC---NEG
KYL-----DDDNATLAIDNTSPDFKLYVTNAIDEDPDKSFENSKFKKIIDRFENIVYLSV
-LLPDTDPVTLDGLFIPNLDPDKLGAV-------------------------------TT
DRTNSPSLRISPQPG------VLSCGDNFGDQSNSEDSSLSDSDRTL-------------
---------------------VGDAPGECQGIFSSSSTSPADQHMTSPMDPAEDMYNYD-
-------------------VLGNPSEEMNWDS-----------HATGVIRNATFFKLLNT
RDCRRGVSDANYAKICKVFVDNRMTLETFKKYLESVV--RVPKEYFKIYRQYPSPDE---
----EWSNLSDTLRLARDGQ---------------TLTVKLGRAL-----------AIN-
---------EFSCKVYLL---------R-----------PESTETNHFLFEHILTRGQSV
GQVKKEILFKAK------KQHMLDIQFNRCRLREKCLKKPRKVYLDDQTFSDDILVLSSY
ELYLQELPYP-------EKVT--STNQLVLFARHWCPATMTLEPFQEVII------DTP-
---TMSELKTKVAELSNIPVENVQVAFVKS------TFPCDMHLLDIHTELEWDPNVT--
-------HLYQ-WPLQV-DDGTAFFYRDGREELKELTYEEK--KEINIRENTRLGRVPLK
SCATL----EKSLRIYLDNWPS-----ETEDNCID----------
>gi|121718827|ref|XP_001276207.	Aspergillus clavatus
---------------------------------MDNVADNEMLVDEYEQYHNDR------
----TDDVVVSRSGSEEPEPEPLADDYPAM---MARILPKD-------------SDLETA
DEAYHTWHIQDWRKLK-KKEHGPVFQCGGFPWRVLFFPYGN-QVEYASFYLEHAWEQEP-
-----------------------PENWYACVQFALVLW-NVNDPSIYVSHVATHRFNADE
GDWGFTRFCELRRLFNMPWEGRGVPLV----QNDEARVTAYVRVVKD-PTGV-----LW-
-HTFQNYDS---KKETGMVGLKNQGATCYLNSLLQSLYFTNSFRKAVYQIPT--------
-EAEA-SKENSAWTLQRLFYNLQTSE-NSVSTTELTASFGWESRQI----FEQQDVQELS
RKLMERLEEKMKGTPVEKALPDLFVGKTKTYIS--CINVDYESSRVEDFWDIQLNVRGN-
-----KTLDDSFKD-YIQVETLEGENKYDAGSPYGLQDAKKGVIFESFPPVLHLHLKRFE
YDINRDAMMKINDRHAFPMEFDASPYL---------------------------------
------------SNDADKSES---------------------------------------
---------------------YMYELHGVLVHSGDLNAGHYYAFLKPTKD---------G
HWYRFDDDRVTRA----TDKEVLEENYGGEYELANGAAGVRQPYTRGLSTKRSMNAYMLV
YVRKTRIDDVLLPITKDD----VPSHIEKRLTEERAEFLRRKKEREEAHLFINVGVL---
-------TEESYR----SHHGFDLT-STDLP---------------AGDPAL--------
-P--KAYRILRATKVREFAEQLAEERGLNANQ------------IRF----WVMVNRQNK
TTRPDQVIKDPDMTVEEA-----------YSRYGTKGNP-----------FKVWME----
-----------------------------VGQPAADG-SIPSPDS------------NNS
VLIFLKNFDVPSQTLTGVGAVYVRKN------------QRVADLAPTILEKMNWPAGTEF
MLFEEIKHNMIDVM----------------------------------------------
--KPKQTFQQSEIQD----------GDIITFQRTVKESELPPAAL---------------
---------------------YTDARQYYDYLLNRIDITFAPFKATDGD-----------
------------------------------------------------------------
--------------EFVLTLSRKMTYDQFSKKVGEHL--NVESTHLRFAPVLASSGKPKQ
FIKRNSNQANQTLYHILSGQVSGYGYSMHRQDA--LYYEVLETSL-----------SDF-
---------ESKVCLKVT---------L-----------LPEGITKEQVIEVLVPRDGTI
SDLLAGLQK---------KANLEDDVVREMRVFEA---HSGKIYKEYQADSRIAPINEYV
SLYAERVPEE-------ELQM----------------------RDGERTI------NAF-
------NFDREPNRSHGVPFKFVLRPG--E------IFKETKERLSKRTGIK-GKQFE--
-------KIKF-AVVPRSLYSNPRY-----LEDDDILSDIV----GDSDDLLGLDH--VN
KNRNFWNRSESFFIR------------------------------
>gi|110758389|ref|XP_392439.3|	Apis mellifera
------------------------------------------------------------
-----MVCRAGQICFIQCSLSGFKDKFTSD------------------------------
-------RLLLHESTRGEELYVYIEEHCQIPQDSFQLYL---VSAGKLINLSEVKDKTM-
--------------------------SEIGVDFSFDRESSSEHKPTLLVMDPT-------
-DILMQKQSSYCIMRHQSAYNPPPPSP---------------------NHSS-----VWG
EDNNIDFKSLI-KSETNYVGLVNQAMTCYLNSLLQALYMTPEFRNALYNWEYID------
-GSEKDEANSIPYQLQKLFLNLQTSTKSAVETTSLTKSFGWDSTEA----WQQHDIQELC
RVMFDALEQKFKNTEQADLINRLYEGKMIDYVK--CLECGTEKSREDTFLDIPLPVRPFG
SNVAYTSVEEALRA-FVQYEILEGSNQYHCEKCNKKCDAHKGLKFTKFPYLLTLHLKRFD
FDFKTFHRIKLNDKVTFPDTLNLNSFIASMP-------------------------NLQE
SPSTDENNSLAKCDDNSITDSGTLDDDYMSN------------------------GPSTS
NCTMHNHENEKNRNSNAAKGPYNYELFSIMIHSGSASGGHYYAYIKDFRT---------Q
EWFCFNDQSVTQ-----ITHDDIQKTYGG---------GSTRSYFSGAY--SSTNAYMLM
YRQIDPTRNAL-PMQVQD----FPKHIQELLKKMKENEDNDRKSREKDLATPKVKVY---
-------CQHPTEDKKLNFRLSFLP-NATWAETTKYVY-----KNFCLEGMV--------
-S----LNQCRLVAYDPNNDLIVASYEGREHETFANIWC-----HRVNRYSLLLEIRDKD
QK--FEPHLRGGIVTKLY-----------VVDVARKKLIEGPLN------VRGLFT----
------------------------QTVKEYKQVVGKF-VNMDPDDMKIVLRKHG---TDT
IFV-----QNDDAILAVAEFCNLVKVFVCTNCDAECNKSYLETIISRIAEQLENIITLRI
RLPPNPSKEMLEELNIPMLEEVCKDKEKSVIDS---------------------------
--PSKTSITESHNRD-----TGTKCNDILKSGKLIEDTPVRNASPQ--------------
-------------LGEGEEWHTPEQSNSEDSSLSDSDKTLVGDAPGDDDFQLPYLPSS--
-------------TSNRAIKMLNQVGIENWDNIIDDSE-----------------YYFKA
TPYTNHNEK-----FLKVLVDKRMIFNTLKKNLEPYV--GVPAEYFKICRYFDECGES--
----DCSCLLSQLVSYEDGE---------------KLWIEIGRAL-----------RNG-
---------EFTVKLHQF---------F-----------LDSAEVCKFLFEWIVSEDMTV
GQAKKEILAEMK------RRYNIEIPYERCRLREKCFVLPSKVLLDHQKF-KDFQFYSQF
EMIVQELPDK-------DPVT--NSNQVIIFVRRWFPTKRHFGPPQEIVL------DET-
---TMEEMMKKLSLISDIPEKYINIMRGKG--------SVHIPVVRVENDEDWIELTSGD
-------ELNV-------EDGAVFLYRDSRETSQPLTQEEY--NDIAIREVSPF--LPLS
SASRYNARKEKALRIYLDVITSCQVFVESSTQQLQNILCFTNYLV
>gi|118091184|ref|XP_420965.2|	Gallus gallus
-----------------------------------------MVPSEENQLVPKE------
----DMFWSCRQSTLAEMKKKFAQVESAAE---EPRVLCII-------------QDTTNS
KTVNERVTLNVPASTPLKKLFEDVASKVGYVNGTFDLVWGNGDNVTDMTPIDQNSDKTI-
-----------------------LDAGFEPGKKNFLHLTDKDGEQPHIMQEES-------
-----------GTTEDSAQDRFIGPLP---------------REGSVGCTND-----YV-
-SQSYSYSSVLSKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-ESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINQLYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SNQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMTFPEELDMSIFIDV-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFSN----------DDG----VDEGICLE
SNSA----AERIAKVGSEKNSLLYELFSVMVHSGSAAGGHYYACIKSFSD---------D
QWYSFNDQHVSK-----ITQEDIKKTYGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPARNAK-FLESHE----YPDHIKQLVQKERELEEQEKRQREIERNTCKIKLF---
-------CMHPTKQIMMENKLEVHK-DRTLKEAVGIAY-----KLMDLEEAV--------
-P----LDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRRPD
QI--FQCYKPGEVMVKVH-----------VVDLKTESVAPPIS-------VRAYLN----
------------------------QTVSEFKQLISKA-THLPAETMRVVLERCY---NDL
RLL-----TVSSKTLKAEGFFRSNKVFIESSESLDRHVAYTDSHLWKLLDRHANTIRLYV
-SLPEQSPGSQFRRSIYQKPSGDLGNLDEACERVKGPAGNMKSVE--------AILEEST
EKLKSLSLQQQQQEG--------DNGDSSKSTEASDFENIESPSNEIDSSASVENRELEN
QI-----------QISDPEN-LQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNVDN
APIPLANGLDSHSITSSRRSKANQGKKETWDTAEEDSGTDSEYDESGKSRGETQYMYFKS
EPYTADEGSGEGQKWLMVHVDKRITLSAFKQQLEPFV--GVPSSHFKVFRVYASNQEF--
----ESVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVYQL---------L-----------VNEPEPCKFLLDAVFAKGMTV
RQSKEELLPQLR------EQCGLDLTIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNW
EVFLEILDGV-------EKMK--SMSQLAVLSRRWRPSEMKLDSFQEVVL------ESS-
---SVEELKEKLSELSGIPLENIEFAKGRG------TFPCDISVLEIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDKTEELMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDLTQD----------
>gi|157020388|gb|EAU77665.2|	Anopheles gambiae
-----------------------------------------------MVCAKDD------
----EALCTIRDVRPDAVQKRFSITVRPHY---TVATLYED-----------VRLQTAFS
DFELHLIGTESDVQIPLHERQQEKLADVGIKFGIVN----NFTIVPRMSLLMPAEDMSS-
-----------------------DDDLALGASASPVESGNYNIPEATAIPPPILR-----
---RFNNDIEIHNTAKSNSLPAIAAPPINSMSGGSIISNGFHHGDGGGGSGEGGGGGLGG
RGRRFGGDGGETEKAPHFRGLVNQAMTCYLNSLLQGLYMTPEFRNALYNWEF--------
-DGED-EAKSIPYQLQKLFVNLQTSPKSAVETTDLTRSFGWDSAEG----WQQHDIQELC
RVMFDALEHKFKRTEEADLINRLYQGHMIDYVR--CLECNTEKQREDKFLDIPLPVRPFG
STVANECVEDALQG-FVKPEILNESNQYFCDTCNKKCDAHKGLKFTKFPYILTLHLKRFD
FDYQSFHRIKLNDKVTFPELLNLNHFVSSTPTLTTSTIAAAAAAAAAAASTTNGTANGNG
PMMMETAENFMKSDECSTTDSGSALEEDSFQNGGTSVSSTTTTPNDQFMAQDDDEGIDMD
LTTNGDSKSSPVNNSFNAPGPYKYELFAIMIHAGSASGGHYYAYIKDFKS---------G
RWFSFNDQTVLP-----ITQEDIHKSYGG---------GSYKTSYTGAYT-SSTNAYMLM
YRQIDSEKNAL-PISEEQ----FPDHIKRLVMKIRANEGNHSRDHL---DMTRLTVA---
-------YENPRTRTIKGHKMAVFT-SSTLAETVQEAV-----RVLHLKGTV--------
-P----VERCRLVGYDCNARTIERSFEGHEEKTIDEVMR-----MLKRCDSLLLEVREEG
ET--FEEYQVQGVMTKVY-----------KVDVNGRDVEGPVS-------IRANLS----
------------------------QTVAQYRAIIARK-LKLNPKAILVGMTVHK---ESA
KLL-----QTDDATLEDEHFIEYCKVFVTVAPTAGDDREQYGARFRHFIQRLDHLVSFYI
-VLPNMDPDTLESLSIPRLSKETLAAIAAADSPMAGGTGDSNSED--------SSLSDND
RTLVEDDFVHIKLNGDLHLTNGGSSGAGAMSNGAAAKGSSKVTATTPTSASNGFKSDD--
-------------EEEDEDAKLAEMLQECRAQEYYFKVTPLNTASSSSNGASNGSSADD-
------------------------------------------------------------
-STRSHSTDSGSQKLVQVLIDKRSCNAYLKYRLQSYL--QISMDYFKVFSSDALC-----
----PTNDSANLLKELEYKDDD-------------RLALELGRVL-----------RKG-
---------EYKLNVSYVNVNQ-----M-----------TEEMDNTPSLCSTIVKNGDLV
GQIKADILASLPAALGEGAKKYAHLHSNNCRLRRKGIKYLSTLYKDDERIGTDITLPTNA
DVFLQEVDDL-------ASLTPIDINDVVLLVRRWHPSEMKLGKFQEILF------TDK-
-----LELTKHLSRISGIPEENIEYVKIPQ------TTLHRDSVLNIQNGLHWVSTPQ--
-------HADD-CQVY--SVGTLLYYRDSTEQLKELTPEER--KELTKKD--------NR
TSSTYSPRKERALKIYLDASPKKADD-------------------
>gi|83771420|dbj|BAE61552.1|	Aspergillus oryzae
---------------------------------MDNVPDNEMLVDEYEQYHNDR------
----TDDVVVSRSGSEEPEPEPLANDYAAM---MARILPKD-------------PELETE
DEAYHTWHIKDWRKLK-KKEHGPTFHCAGFPWRILFFPYGN-HVEHASFYLEHAWDNEP-
-----------------------PENWYACVQFGLVLW-NVNDPSIKISHVATHRFNADE
GDWGFTRFCELRRLFNLAWEGRGVPPV----QNDEAMVTAYVRVVKD-PTGV-----LW-
-HSFQNYDS---KKETGMVGLKNQGATCYLNSLLQSLYFTNAFRK---------------
----------------RLFYNLQTSE-NPVSTAELTASFGWESRQI----FEQQDVQELS
RKLMERLEEKMKGTPAEKALPELFVGKTKTYIS--CINVDYESSRVEDFWDIQLNVRNN-
-----KTLDDSFKD-YIQVETLEGENKYDAGPPYGLQDAKKGVIFESFPPVLHLHLKRFE
YDINRDAMMKINDRHAFPMEFDATPYL---------------------------------
------------SNDADKSEP---------------------------------------
---------------------WVYQLHGVLVHSGDLNAGHYYAFLKPTKD---------G
YWYRFDDDRVTRA----TDKEVLEENYGGEYELANGAAGVKQPYTRGLSTKRSMNAYMLV
YIRKSRLDDVLLPIMKED----IPSHIETRLIEERVELARRKKEREEAHLYINVGVL---
-------NEESFK----SHHGFDLT-SLDLP---------------AGDPAL--------
-P--KQYRILKALKVGEFAEQLAQEKGIDANR------------VRF----WVMVNRQNK
TTRPDQVIKDPDMSVEEA-----------YSRFGTKGNP-----------FRVWME----
-----------------------------VGQPSADG-TVSWPDN------------NNS
VLVFLKHFDAPSQTLSGVGPVYVRKN------------QKVAELAPTILEKMEWPAGTEF
MLYEEIKHNMIDVM----------------------------------------------
--KPKQTFQQSEIQD----------GDIITFQKSIKEADLPSTAL---------------
---------------------YQDARQYYDYLLNRISVTFAPIKAGEGD-----------
------------------------------------------------------------
--------------EFTLTLSRKMTYDQFSKKVGEHL--NVESTHLRFAPVMASTGKPKQ
FIKRNPNQANQTLYQILSGTMTGYGYSMHRSDA--LYYEVLETSL-----------SDY-
---------ESKTSLKVT---------W-----------LPEGITKEQVVEVLVPRDGTI
SDLLSGLQK---------KANLDEDTIREVRIYET---HAGKIYRDFPVDTKIAGINEFV
TLYAERMPEE------------------------------------EVNM------GEGE
RTINAYNFDRDLNRPHGVPFKFVLKPG--E------VFKETKERLSKRTGIK-GKQFE--
-------KIKF-AAVPRSLYSSPRY-----LEDDDILSDIV----GDSDDLLGLDH--VN
KNRSFWNRSESFFIR------------------------------
>gi|19173018|ref|NP_597569.1|	Encephalitozoon cuniculi
------------------------------------------------------------
------------------------------------------------------------
--MDEGWKVKRPSS--GAKVESKPFSVQGHTWKLIL------SNRCNRVYLALEYQG---
-----------------------GSYHDILTAFCFDIDGKKYEYQYQFSMFSTD------
-----------IGMYIEEKERYV------------------IRVDVRVRTGC--------
------YNS---KEETGYVGLRNLGATCYINSLMQALFSIAKFRNDVFGLEP--------
--------RGRVLLLQKLFKEMQTGE-HPVDTTDFVVNNIW-VDDV----HVHQDIHEFS
KVFFDSLE---KDSKRKDVIEDMIQGELVTYINGKC---GCVRRIKEKFQDIQVEIRDFF
NNKLSSNLQESLKR-YVKSEILDGNNRYNCEK-HGLVDAKKGVMFSSLPPVMFILLKRFN
VDFETGNGYKINDYFEFPDSIDMLPFL---------------------------------
------------DRDSKRKEE---------------------------------------
-------------------SDATYDLYSVIVHRGDHDEGHFYAYLKIN-----------G
RWLKFNDTVVTEA----GEMEALEHNFGG-----------RHPYKDRI---RDHSGYYLI
YLRKSMANDLLNAKVV------IPPRTEEVLSRKQDKTLVRCIRIDNIRNYRGIGFY---
-------NIDSYDYPLSSYAEFVMK-----------------------------------
----------EGDTIKLLRNNIEKHLSTRKSL------------YLF------ECTRIKS
HEKGETSDRPCKRVKEDT-----------RELVGTNTRTVEEEASRIIEHVQLDYQ----
------------------------RKVALVKDGVINVSADYFVYTCHPGV--NF---EGH
RLIFLKVFN--SIPWCEDTLPTSLRL-----CACVHMDGTIGDNIDVIGEKTGLD---DI
AVFREFDFSS--------------------------------------------------
--ALDPSTKISDLPQ----------GDVLVAVRRENVLEF--------------------
---------------------LDFIGDFYRRLCVNVSCGPH-------------------
------------------------------------------------------------
--------------NFTIFVKRGLKSTELEDRIRRFV--GSKEIFLRKEAVSDSSEFRTA
PEDSVQSDPEPDLHEYLQPRNSVSCFIS-------AGYQVVYLAFC---------NKEM-
---------DYNAVPHLH---------I-----------------------LVTKVGCTS
LELIKSVLVSR-------FVCLNPVRGHSLKTLRIVDTVRDTLYLKAFAMSEEFTTNGMC
VI----------------------------------------QPFVRRAI------KTA-
-------YYTGMYKIVGFPFFLQADVETVT------EFRKKYKLFGKMVMFD-GKSYT--
-------DLELDWPMSKFNDECFLLIERT-------------------------------
---------------------------------------------
>gi|125813120|ref|XP_699037.2|	Danio rerio
------------------------------------------------------------
----QINTCAWSTKLKSCVFVYLQIESAAE---EPRVLCIV-------------QDTTNA
KTVNERLTLNLPASTTLSKFFEDVAHKAGYVNGTFCLSW---ANTGDMAPLDQASEMSL-
-----------------------VMSGFEAGKRNFLQLTDKDGEQPQIASVNS-------
-----------GGLDDSSQDRFIGPLP---------------RDGTVGCSSD-----YS-
-SPSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYNWEFE-------
-DSEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINQLYQGKLKDYVR--CLECGYESWRIDTYLDIPLVIRPFG
ASQAFGSVEEALQA-FIQPETLDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMTFPEELDMSPFIDV-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFST----------DDG----VDEGICLD
NASS----AERVLKP---KSSLTFELFSVMVHSGSAAGGHYYACIKSFSD---------S
QWYSFNDQHVSK-----ITQDDIRKTYGGS--------SGSRGYYSSAFA-SSTNAYMLM
YRLKDPSRNAK-FLEVED----FPEHIKRLVQREKESEEQEKRQREIERNTCKIKLF---
-------CMHPVKMMMMENKLEVHK-DKTLNEATEMAY-----KLMDLEGVV--------
-P----LDCCRLVKYDEFHEYLERSYEGEEDMPMGLLLGGVKSSYMF---DLLLEIRRPE
QA--FQPYKPGEVMVKVH-----------VVDLKSESIAAPVS-------VRAYLN----
------------------------QTITEFKQLIAQA-TGLCAETMRVVLERCY---NDL
RLL-----YVPNKTLKAEGFFRSNKVFVESSDSTDHQAAFTDSVLWKLLDRHGNTIRLFV
-SLPEQSPGSFANRTSCPKASADSE------DSFDGAKAGRKSVE--------AILEEST
EKLKNLSLQQQQQQQ-----QTSSTSDSQKSSEHSDFEHIESPAQEPDASSQPSQTENCT
R------------AASDTDNQFPSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADS
GPLPLANGLDSHSITSSRRSKAHEGKKETWDTAEEDSGTDSEYDENGKSKADTQYLYFKA
EPYSQEDGAGDGQKSLLVHVDKRITLAAFKQNLEPFV--GVPSTQFKVFRVYANNQEF--
----ESVRLNETLSFFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVYQL---------L-----------VNDPEPCKFLLDTVFAKGMTV
RQSKEELLPQLK------DQCKLDLSIDRFRLRKKTWKNPGTVFLDYHVYEEDINISSNL
EVFLEVLEEP-------ERMK--SMSQLAVLTRRWCPAQMKLEAFREVVL------ESS-
---SVEELKEKLSEVSGIPLENLEFAKGRG------TFPCDISVLEIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDSSEELMELSEEER--NELMKKESSRL--LKTG
HRVSYSPRKEKALKIYLDGGPT-------KDPGLD----------
>gi|24641480|ref|NP_572779.2|	Drosophila melanogaster
MEIETDQSIEAMDTQDTQEVEILTSDLQQTQQQRNSPPQLPKFKNLIQPQLHAV------
----GAVTQLPSENGNMPPQQLLADSSSTSFGDGEAMGIDD-----------ESKEDQFR
SETTFSFTVENVVQLKSQRLSPPVYVRM-LPWRIMVIP----NDRALGFFLQCNGEND--
-----------------------SPTWSCNAIAELRLKCHKPDAQPFTRARIKHLFYSKE
NDYGYSNFITWQELKDSEKSYVHNNSI-----------TLEVHVVADAPHGV-----LW-
-------DS---KKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPT--------
-EADD-SSKSVGLSLQRVFHELQFGD-RPVGTKKLTKSFGWETLDS----FMQHDVQEFL
RVLLDKLESKMKGTILEGTIPGLFEGKMSSYIK--CKNVDYNSTRYETFYDIQLNIKDK-
-----KNIYESFQD-YVAPETLEGDNKYDAGV-HGLQEASKGVIFTSFPPVLHLHLMRFQ
YDPVTDSSIKYNDRFEFYEHINLDRYL---------------------------------
------------AESENTLAD---------------------------------------
-----------------------YVLHAVLVHSGDNHGGHYVVFINPKAD---------G
RWFKFDDDVVSSC----RKQEAIEQNYGGM--------DDEISFHA-----KCSNAYMLV
YIRQSELDRVLGDITESE----ISSDLVERLDLEKRIEMARRKERGEANTYVSVHVI---
-------LEENFE-------------EQHKR------------RLFDLEKVH--------
-P--RVFRIKQNQTVDELVDLFVRGFGVSRQR------------MRM----WNLCTAQTQ
KFSHFDFVAEGSRTIE-------------QISTSQKP-------------WVIWLQ----
------------------------LAWTDVPGPLPPF---------------NP---KTE
SLLFLKYYDPRNKRLNYIGCTQQPHT------------RRLIDLVPDVNSKLGFEPDTEL
TIYDEYADKKLVNL---------------------------------------------N
EPIESALFIPQDHLQ----------GHILIFERENVDAKLD-------------------
---------------------LPTVGDYFLDLVYRIEIIFSDKCNPNEP-----------
------------------------------------------------------------
--------------DFTLELSNRYNYDQLANAVAERL--NTDPQKLQFFMCINNYKET--
--------AGNAVPYTFKGTIKDLVSYTKQSSTKRIFYQRLSLSI-----------HEL-
---------DNKKQFKCV---------W-----------VSSDLKDEKELVLYPNKNDTV
KGLLEEAAK---------KISFAENSRRKLRLLKISNHKIVAVCKDDIPLDTLLKSNESI
TTAQGAQKTF----------------------------RIEEVPAEDMQL------AENE
FLIPVAHFSKELYNSFGIPFLTKARQG--E------PYGALKQRIQRRLNVQ-DKEWE--
-------NYKF-CVISMGHNAD---VNDNTPVDLEVYRSWT----SGQLPFFGLDHINKS
RKRSSLNFSEKAIKIYN----------------------------
>gi|109107292|ref|XP_001098793.	Macaca mulatta
-----------------------------------------MVPGEENQLVPKE------
----DVFWRCRQNIFDEMKKKFLQIENAAE---EPRVLCII-------------QDTTNS
KTVNERITLNLPASTPVRKLFEDVANKVGYINGTFDLVWGNGINTADMAPLDHTSDKSL-
-----------------------LDANFEPGKKNFLHLTDKDGEQPQILLEDS-------
-----------SAGEDSVHDRFIGPLP---------------REGSVGSTSD-----YV-
-SQSYSYSSILNKSKTGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-ESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINELYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SSQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMTFPEELDMSTFIDV-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFSN----------DDG----VDEGICLE
TNSG----TEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSD---------E
QWYSFNDQHVSR-----ITQEDIKKTHGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPARNAK-FLEVDE----YPEHIKNLVQKERELEEQEKRQREIERNTCKIKLF---
-------CLHPTKQVMMENKLEVHK-DKTLKEAVEMAY-----KMMDLEEVI--------
-P----LDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRKPD
QV--FQSYKPGEVMVKVH-----------VVDLKAESVAAPIT-------VRAYLN----
------------------------QTVTEFKQLISKA-IHLPAETMRIVLERCY---NDL
RLL-----SVSSKTLKAEGFFRSNKVFVESSETLDYQMAFAESHLWKLLDRHANTIRLFV
-LLPEQSPGSYSKRTAYQKAGGDSGNVDDDCERVKGPVGSLKSVE--------AILEEST
EKLKSLSLQQQQDGD---------NGDSSKSTETSDFENIESPLNERDSSASVDNRELEQ
HI-----------QTSDPEN-FQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADN
AQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKA
EPYAADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFV--GVLSSHFKVFRVYASNQEF--
----ESVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVYQL---------L-----------VNEQEPCKFLLDAVFAKGMTV
RQSKEELIPQLR------EQCGLELSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNW
EVFLEVLDGV-------EKMK--SMSQLAVLSRRWKPSEMKLDPFQEVVL------ESS-
---SVDELREKLSEISGIPLEDIEFAKGRG------TFPCDISVLDIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDKTEELMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDLTQD----------
>gi|126332479|ref|XP_001379670.	Monodelphis domestica
------------------------------------------------------------
-----MFWRCRQSIFDEMKKKFSQIENAAE---EPRVLCII-------------QDTTNS
KTVNERITLNLPASTPLRKLFEDVANKVGYVNGTFDLVWGN-GISATDMPLDHTSDKSL-
-----------------------LDTNFEPGKKNFLHLTDKDGEQPQILSEDS-------
-----------SAVDDSVQDRFIGPLP---------------REGSVGSTGD-----YV-
-SQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-ESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINELYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SSQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMTFPEELDMSTFIDI-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFSN----------DDG----VDEGICLE
SSSG----TEKITKPGLEKNSLLYELFSVMVHSGSAAGGHYYACIKSFSD---------E
QWYSFNDQHVSR-----ITQEDIKKTHGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPSRNAK-FLEVND----YPEHIKSLVQKEKELEEQEKRQREIERNTCKIKLF---
-------CMHPVKQVMMENKLEVHK-DKTLKEAVEIAY-----KMMDLEEVI--------
-P----LDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRKPD
QV--FQSYKPGEVMVKVH-----------VVDIKTESVAPPVS-------VRAYLN----
------------------------QTVTEFKQLISKA-IHLPAETMRIVLERCY---NDL
RLL-----NVSSKTLKAEGFFRSNKVFVESSESLDRQMAFTDSHLWKLLDRHANTIRLFV
-LLPEQSPGSHSKRTAYQKAGGDSGNVDDACERVKGPLGSLKSVE--------AILEEST
EKLKSLSLQQQQDGD---------NGDSSKSTETSDFENIESPLNERDSSGSVDNRELEQ
QI-----------QTSDPEN-FQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADS
APVPLANGLDSHSITSSRRSKANEGKKETWDTAEEDSGTDSEYDESGKSRGETQYMYFKA
ESYAADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFV--GVLSSHFKVFRVYASNQEF--
----ESVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVYQL---------L-----------VNEQEPCRFLLDAVFAKGMTV
RQSKEELLPQLR------EQCGLELSIDRFRLRKKTWKNPGTVFLDYHVYEEDINISSNW
EVFLEVLDGV-------EKMK--SMSQLAVLSRRWRPTDMRLDPFQEVVL------ESS-
---SVDELREKLCEISGIPLEDIEFAKGRG------TFPCDISVLEIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDKTEELMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDLTQD----------
>gi|114636190|ref|XP_001171078.	Pan troglodytes
-----------------------------------------MVPGEENQLVPKE------
----DVFWRCRQNIFDEMKKKFLQIENAAE---EPRVLCII-------------QDTTNS
KTVNERITLNLPASTPVRKLFEDVANKVGYINGTFDLVWGNGINTADMAPLDHTSDKSL-
-----------------------LDANFEPGKKNFLHLTDKDGEQPQILLEDS-------
-----------SAGEDSVHDRFIGPLP---------------REGSVGSTSD-----YV-
-SQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-ESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINELYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SSQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMTFPEELDMSTFIDV-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFSN----------DDG----VDEGICLE
TNSG----TEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSD---------E
QWYSFNDQHVSR-----ITQEDIKKTHGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPARNAK-FLEVDE----YPEHIKNLVQKERELEEQEKRQREIERNTCKIKLF---
-------CLHPTKQVMMENKLEVHK-DKTLKEAVEMAY-----KMMDLEEVI--------
-P----LDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRKPD
QV--FQSYKPGEVMVKVH-----------VVDLKAESVAAPIT-------VRAYLN----
------------------------QTVTEFKQLISKA-IHLPAETMRIVLERCY---NDL
RLL-----SVSSKTLKAEGFFRSNKVFVESSETLDYQMAFAESHLWKLLDRHANTIRLFV
-LLPEQSPGSYSKRTAYQKAGGDSGNVDDDCERVKGPVGSLKSVE--------AILEEST
EKLKSLSLQQQQDGD---------NGDSSKSTETSDFENIESPLNERDSSASVDNRELEQ
HI-----------QTSDPEN-FQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADN
AQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKA
EPYAADEGSGEGYKWLMVHVDKRITLAAFKQHLEPFV--GVLSSHFKVFRVYASNQEF--
----ESVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVYQL---------L-----------VNEQEPCKFLLDAVFAKGMTV
RQSKEELIPQLR------EQCGLELSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNW
EVFLEVLDGV-------EKMK--SMSQLAVLSRRWKPSEMKLDPFQEVVL------ESS-
---SVDELREKLSEISGIPLDDIEFAKGRG------TFPCDISVLDIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDKTEELMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDLTQD----------
>gi|109462693|ref|XP_001074180.	Rattus norvegicus
-----------------------------------------MVPGEENQLVPKE------
----DVFWRCRQNIFDEMKKKFLQIENAAE---EPRVLCII-------------QDTTNS
KTVNERITVNLPASTPVRKLFEDVANKVGYINGTFDLTWGNGINTADLAPLDHTSDKSL-
-----------------------LDANFEPGKKNFLHLTDKDGEQPQMLLDDS-------
-----------SHVDDSVHDRFIGPLP---------------REGSVASTSD-----YV-
-SQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-ESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINELYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SSQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMSFPEELDMSTFIDI-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFST----------DDA----VDEGICLE
SSTG----SEKISKPGLEKNSLMYELFSVMVHSGSAAGGHYYACIKSFSD---------D
QWYSFNDQHVSR-----ITQEDIKKTHGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPTRNAK-FLEVDE----YPEHIKNLVQKERELEEQEKRQREIERNTCKIKLF---
-------CLHPVKQVMMENKLEVHK-DKTLKEAVEMAY-----KMMDLEDVI--------
-P----LDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRKPD
QI--FQSYKPGEVMVKVH-----------VVDLKAETVAAPVT-------VRAYLN----
------------------------QTVLEFKQLISKA-THLPAEPMRIVLERCY---NDL
RLL-----SMPSKTLKAEGFFRSNKVFVESSETVDHQAAFTDSHLWKLLDRHANTIRLFV
-LLPEQSPGSYSKRTAYQKAGGDSGNVDDDCERAKGPAGSLKSVD--------AILEEST
EKLKSLSLQQQQDGD---------NGDSSKSTETSDFENIESPLNERGSSTSVDNRELEQ
HI-----------QTSDPEN-FQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADS
AQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKA
DPYTADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFV--GVLSSHFKVFRVYTSNQEF--
----ETVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVCQL---------L-----------VNEQEPCKFLLDAVFAKGMTV
RQSKEELIPQLR------EQCGLDLSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNW
EVFLEVLDGV-------EKMK--SMSQLAILTRRWRPSEMKLDPFQELVL------ESN-
---SVDELREKLSEISGIPLEDIEFAKGRG------TFPCDISVLDIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDRTEEVMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDVAQD----------
>gi|19112133|ref|NP_595341.1|	Schizosaccharomyces pombe
---------------------------------------------MVLSNVDAE------
----EVNMDSSMELEESSQEPLRADNYEEI---YNSLVHHE-------------PDLEEA
AHASYSWVVKNFSTLE-DKTYSPLFKAGHTTWRIVLFPKGCNQTEYASVFLEYLPQCKVE
AIRKYEAELAAGKTPTIDPEIVNDETYSCCAQFALSLS-NVQDPTVMQINTSHHRFRSEV
KDWGFTRFVDLRKIAVPTPEFPVPFLE-----NDEICISVTVRVLQD-PTGV-----LW-
-HSFVNYNS---KKETGYVGLKNQGATCYMNSLLQSLFFTNIFRKTVYKIPT--------
-DNDD-SRDSVAYALQRVFYNLEKQR-EPVSTTELTRSFGWNSFDS----FMQHDIQEFN
RVLQDNLEKKMKGTEVENALNDIFVGKMKSYVK--CIDVNYESSRVEDFWDIQLNVKGM-
-----DTLEDSFRD-AIQVETLTGDNKYYAEG-HGLQDAHKGIIFESLPNVLQLQLKRFD
YDMLRDMMVKINDRHEFPLEIDLEPYL---------------------------------
------------SETADKSES---------------------------------------
---------------------HVYVLHGVLVHGGDLHGGHYYALIKPEKD---------S
NWFKFDDDRVTRA----TIKEVLEDNYGGE------PAGRAKGYNGNPFK-RFMNAYMLV
YFRKSRLDHILSPVTAED----VPFHVRNTLDEEHRVVERKLLEREEQQIYRRVRVL---
-------TTDGFK----KYHGFDMT-DFSAS---------------DDDPVL--------
-I---TTKIKRNANIWDLQKHLAGLLNRDTSG------------IRI----WLMTNRQNR
TVRVDLPLDKKTILVDQ------------ICDMHIRKDMD----------MRVYVE----
-------------------------FLSEHNQLLADF-----------GATDDN---DFD
TYIFLKIFDYETQQISGLADLHVSKN------------SPISSLSEWIREHLKWSSDVPI
TYYEEIKTGMVDVL----------------------------------------------
--DPNASFEKSEIQV----------GDIICFEKKLVHDSSSDTSHP--------------
---------------------YKSALDLYDFMAHRVVITFEPRY----------------
------------------------------------------------------------
-------SDDTNNGVFDLVLTTHTNYTDMARAVANKL--NVDPNYLQFTMAHLPSR----
----TPRSVIRNPSKFTLQNAIPSTYSHNQNVV--MFYEVLDITL-----------SEL-
---------ERKQLIRVH---------F-----------LSNGISHETQMEFYVDKEGTV
EDILRQVTQ---------KVPLNAEDASRLRLYEVYNHR---ILKSHLPTDGIYDLNEFS
TAYVEVTPKE-------EQMQ------------------LKTDDAVSIVV------Q---
------HFFKDLSRLHDIPFYFVLLRG--E------TLKDLKKRLQKRLGYN-DTQFS--
-------KVKL-AVLQAQSFGKPYY----LTDDDEVLYGEL----EPQSHILGLDHPPAN
GSAQYHGM-DQAIRMK-----------------------------
>gi|47230431|emb|CAF99624.1|	Tetraodon nigroviridis
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MVPSEENQFVPKEAPLDHRSEMSL-
--------S--------------DSGFEPGGKRNFLHLTDKDGEQPQLASDES-------
------GAADSSGLDDSSQERFIGPLP---------------RDGSVGCSGD-----YS-
-SPTYSYSSILNKSDTGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYNWEFE-------
-ESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTVQADLINQLYQGKLKDYVR--CLECGYESWRIDTYLDIPLVIRPFG
ASQAYGSVEEALQA-FIQPETLDGPNQYFCERCQKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMTFPEELDMSPFIDV-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFST----------DDC----VDEGICLD
STNN----ADRMLKP---KSLLTFELFSVMVHSGSAAGGHYYAHIKSFSD---------G
QWYSFNDQHVSK-----ITQEDIRKTYGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPSRNAK-YLSVED----FPEHIKSLVQKEKESEEQEKRQREIERNTCKIKLF---
-------CIHPIK-MMMESKLEVHK-DKTLREATEMAY-----KLMELEGLV--------
-T----LDCCRLVKYDEFHEYLERSYEGEEDTPMGLLLGGVKSSYMF---DLLLETRRPD
QV--FQPYKPGEVMVKVH-----------VVDLESKTIAASVS-------VRAYLN----
------------------------QTITEFKQLIAQA-TGLSAETMRVVLERCY---NDL
RLL-----YVPNKTLKSEGFFRSNKVFVESSVSTDHQVPFTDSLLWKLLDRHGNTIRLLV
-LLPEQSPGTLTNRTVCQKVGADSD------ASLDGSKDKRKSVD--------AILEEST
EKLKNLSLQQQQQQQQQQQGSSTSTSDSQKSSDASDFEHIESPTQDADSNSLLCEAADNR
ELENRIGVAGGSGASSDPENHFACEERSDSEVNNDRSTSSVDSDILSSSHSSDTLCNADS
GPLALANGLDSHSITSSRRSKAHEGKKETWDTAEEDSGTDSEYDDNGKSKGEAQYLYFRA
EPCLQSDSTCDPQKCLVVYVDKRITLAAFKQNLEPYV--GVPSTQFKVFRVYANNQEFE-
----SVR-LNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVYQL---------L-----------VNESEPCKFLVDTVFAKGMTV
RQSKEELLPLLK------EQCKLDLNIDRVRLRKKTWKNPGTVFLDYHVYEEDISISSNW
EVFLEVLSES-------EKMK--SMSQLAVLTRRWSPSTMKLGPFQEVIL------ENS-
---SVDELKEKLSEMSDISLENLDFAKGRG------TFPCDISVLEIQQDLDWNPKVS--
-------TLNV-WPLYICDDGAVVFYRSSTEEPMELSEDER--NELMKRESSRL--LKTG
HRVSYSPRKEKALKIYLDGGPT-------KDPGQD----------
>gi|76614658|ref|XP_609625.2|	Bos taurus
------------------------------------------------------------
------------------------------------------------------------
-----MKKIQVLLPPKPRLLKEQLKISQGGDVGKFCF-------KNKDIYITCH------
--------------------------IFLRVVFSFTMFGDLFEEDYSSVSNNN-------
-----------GKGKRLKTKALEPPAP---------------------------------
------------REFTNLSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGLEELGSLED
KDKPDAKVRIIPLQLQRLFAQLLLLDQKAVSTADLTDSFGWTSDEE----MRQHDVQELN
RILFSALETSLVGTSGHDLINRLYHGTIVNQIV--CKECKNVSEKQEDFLDLTVAVKNV-
-----SGLEDALWNMYVEEEVFDCDNLYHCGNCDRLVKAAKSAKLRKLPPFLTISLLRFN
FDFVKCERYKETSCYTFPLRINLKPF----------------------------------
------------CEQSELDDL---------------------------------------
--------------------EYMYDLFSVIIHKGGCYGGHYHVYIKDVDHL--------G
NWQFQEDKSKPD-----VNLEDIQNKEEV---------DDPLMILKAILLQE----SNLI
--PVDQLGQKLLKKIGIS----WNKKYRKQYGPLRKFLQVHSQIFLLSSDESTVRLL---
-------KDSSLQ----AESDIQRN-DQRLFKTLTSES-----LTLNDRPSC--------
-P--HWFDINDSTVQPIKEKDIEQQFQGKESA------------YMLFYRKSQLQ-RPPE
ARANPRYKVPCHLLSEMD-----------AANIELQIKRAECDSTNNTIELHLHLGPHYH
FFNGALHPVVSQTESMWDLTFDKRKTLGDLRQSIFQL-LEFWEGDMVLSVAKFV---PAG
LHVCQTL-NGDDLALCEIEITDGEDIFVWNGVEVGGIQIPTGSDCEPLLLNVLH------
-VATSSEGEECQQLIESPHVFPSNAEIGTVFTALAIPEGVILINN--TESRGGESWITIP
KEDLKKTFREQGLRN----------GSSVLIQGSNNGNSLLTKQGKWIDTVNEINWLQVR
NL-----------SQLESEEEQVKISATLNTVVFDIRIKAIKELKLLKELAENSCLRP--
-------------IDRNGKLLCPVPDRCTLKEAGLKMGSSLGLCPGKAPTSSQLFLFFAL
G------SDVHPGTEMEIIVEETISVRDCLKIMLDKC--GLTGETWHLRKMDWCFEAGE-
----PLCEEDAKLKELMICSGDTLLLIEGKLPP--LGFLTVPIWWY---------QPQG-
-PLHHWKDHQDQTNCTLSQGSV-----WKASSTPGAPSDAHAEVSLWYLGDLEISEDATL
GELKSQAMTLP-------SLEFSIPSPAFLRAWTVENKRPGRLLRGHQQQLKEYKLGKRT
EICLEPLQKE-------ENL---GPWDVLLRTQMRLPGKRAYGPPVDVLW------DTA-
RGWTASSLRQRVADVYSLPVEKIEIAK---------YFPDKFAWLPVS---SWSQQTTKR
KKKKKQDNLQG-APYYL-KDGDTIGVKNLLVEDDDDFSTVQ--DDIGREKLKEVALGKRK
SREALRAQSSDVSSVEMPAQAR------GPEASLSIHVGSFR---
>gi|149720042|ref|XP_001501242.	Equus caballus
-------------------------MRALERLLEPGGAASRRDLACFSQLQCSKTFREGR
CRSWDVFWRCRQNIFDEMKKKFLQIENAAE---EPRVLCII-------------QDTTNS
KTVNERITLNLPASTPLRKLFEDVANKVGYINGTFDLVWGNGINTADTAPLDHTSDKSL-
-----------------------LDANFEPGKKNFLHLTDKDGEQPQILLEDS-------
-----------SAGDDSVHDRFIGPLP---------------REGSVGSTSD-----YV-
-SQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-ESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINELYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SSQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMTFPEELDMSTFIDV-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFSN----------DDG----VDEGICLE
NNSG----TEKISKPGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSD---------E
QWYSFNDQHVSR-----ITQEDIKKTHGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPARNAK-FLEVDE----YPEHIKSLVQRERELEEQEKRQREIERNTCKIKLF---
-------CLHPVKQVMMENKLEVHK-DKTLKEAVEMAY-----KMMDLEEVI--------
-P----MDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRKPD
QV--FQSYKPGEVMVKVH-----------VVDLKAESVAAPIT-------VRAYLN----
------------------------QTVTEFKQLISKTVVHLPAETMRIVLERCY---NDL
RLL-----TAPSKTLKAEGFFRSNKVFVESSETLDYQMAFTDSHLWKLLDRHANTIRLFV
-LLPEQSPGSYSKRTAYQKAGGDSGNVDDDCERVKGPVGSLKSVE--------AILEEST
EKLKSLSLQQQQDGE---------NGDSSKSTETSDFENIESPLNERDSSASVENRDLEQ
HI-----------QTSDPEN-FQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADN
AQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGETQYMYFKA
EPYAADAGSGEGHKWLMVHVDKRITLAAFKQHLEPFV--GVLSSHFKVFRVYASNQEF--
----ESVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVYQL---------L-----------VNEQEPCKFLLDAVFAKGMTV
RQSKEELIPQLR------EQCGLELSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNW
EVFLEVLDGV-------EKMK--SMSQLAVLSRRWRPSEMKLDPFQEVVL------ESS-
---SVDELREKLSEISGIPLEDIEFVKGRG------TFPCDISVLDIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDKTEELMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDLAQD----------
>gi|150865633|ref|XP_001384939.	Pichia stipitis
MDANAGNGVTPQKRAANNDIIDLDSDYEAIDDGQANGRRKENDIVEISNDEDDDLDG---
----DIDYDVDEDDDENDHIDSIAHKDSAAKKSINGIPPADDFAANAARLMKPIVDYPVK
DEAHYVWEIKDWHGLKEEKVRSPRFKCGDFEWNILLFPRGNGRDNAISIYMEPHPIPDEN
GAI--------------------SDDWYVCAQFGLDIWNPVY-PHSHIPSGSSHRFNKNE
TDWGFSSLID-GKQLTSANNSRIGNQPHAILENNQLNITGYVKIIDDSSTGV-----LW-
-HSFIDYDS---KKSSGFVGLNNQGATCYLNSLLQSYFTTLNFRKLVYQIPT--------
-NTASNSKQSVALSLQRIFYLLSSSK-EPVGTLELTKSFGWDSSDA----FTQHDVQELN
RILMDKLETAMKGSKIENSLNDIFVGKMKSYIK--CVHVPYESSRVEDFWDIQLNVKGF-
-----ANLQQSFKN-YIEIEMLEGENKYQAGDEYGYQDAKKGVVFESFPPVLHLQLKRFE
YDFMVDDLVKIDDFYEFPDKIDLKPYL---------------------------------
------------DEDLPEEVR---------------------------------------
------------------NQNWNYKLHGVLVHQGSISNGHYYAMIKPHAKG--------E
TWLRFDDDKVWKV----THSQVFKENFGANEVTSEEFSKMSRLEQQENLVRRVTSAYMLV
YYRESELDSVL-PSDEENLNAVIPEHIPRQIKHESEERERLERLKQEALYYTNVKFI---
-------TTSTIN----EYTGFDLALDPRVPKFYD--------ENLLGTPAE--------
-P-L-VFKVKKDDRFLSLNQLVGKHLKYFEEDDDDEVLDDKQLFFRL----IATCHRKNN
TNRTDTEVADELKDATIN-----------SVYFKAFNRKHDE--------MVFYVE----
ELNKDIRNIVQSVPSTGPIDPSEFQFSTVFNKLKEVG--TKQLDSFKFHNIFDY---SNH
ILIFVKYFDPISQELRGLSHIVVSKV------------EPISSIIKPINELLDFDPNYQL
DMFEELSPSKIDKL----------------------------------------------
--DRSLTFEKQELSN----------GDIITVQPHNSSELASGKK----------------
---------------------FEDVRDYYKFILTRMHIVVKPFKADIDEEDSDFVADEN-
------------------EELKISGEAEDITKNSDDEITTK-------------------
----EIEAAKQISKSFELWISTSYSYQDLAEEIARKLEADVDPQYLRIFVLNNQMQRY--
----PLKSIHQLSSFFPKTVPINQVVT--------FEYEILNIKL-----------KDY-
---------ENLKSVKIH---------W------------LSSLLQYQVFELLVPRNGLV
LDLINKLLH---------KVNVPKKDLKHILLWAGSNHSYQALIRFDNPIEQ---LQDGI
DLYAGIFPAEVEILTNHDMFKRFVNDPVDLNEFDNEFLKEEYQLSKELSK------DMN-
-MIPAFHFYKSIGYHHGIPFILAIYPK--E------KFSQTKERLRRKLGLG-IQAFE--
-------KIRF-SLSDSHDKGAYI----DNEDDDFILFDEI--GKAHTSISFGLDHPDRS
PRRQ--GQSDKGISIN-----------------------------
>gi|45200740|ref|NP_986310.1|	Ashbya gossypii
------------------------------------------------------------
-------MDVPETRETNMEAVELGKTFEEV------LPPLE--------------GEETE
YEGRFTWRIERWSELRGEKHYSPRVQVGRWEWDLLVFPHGN-STKGIAMYLAPHPVQA--
-----------------------EADWYVCAQFAIVLSRPGDDARTQLVSRSQHRFNAVD
KDWGFSNLIELEHLRFATRGRPSGFLS-----GDQLNVTVYVRVLRD-PTGV-----LW-
-HNFANYDS---KKVTGYVGLKNQGATCYLNSLLQSYYFTKYFRKLVYQIPT--------
-EGET-PANSVSLALQRAFFQLQRSS-EPLDTCELTRSFGWDTGDA----FTQHDVQELN
RILMDRLENKMKGTEVEGKLNGLFVGKMKSYIK--CVNVDYESSRVEDFWDIQLNVKGL-
-----KGLQQSFEN-YIEVEMMDGENQY-AAQGHGLQDAKKGVLFESFPPVLHLQLKRFE
YDFNYDQLIKINDRYEFPESIDLSPYLDP-------------------------------
----------EVQEDSPANAK---------------------------------------
-----------------------YNLHGVLVHTGDISTGHYYAMIKPGLE---------D
AWYRFDDDKVWRV----TKKQVFEQNFGFDKLSEYDLRSLTKEQYQNYLIARQTSAYMLV
YIREDMESTILQEVTDAD----VPEYIVNTIEEELKERERFQKEREEMHLYAKVYVH---
-------SMKNFI----HYQGYDLS-PNERSKLY-IPE-----LHGEDEYAL--------
-S----VKLPKNTKVKEIYTLFNEKLGIKRTD-----------LVRY----WTINYRTNT
SLRLDLPILPSYDEMTLE-----------SLMTSQGRNTA----------IDLFVE-ESY
FDLGYIHSIWDELDTS--------QNFADVLQQVKDMVNEGLLPSSETYIREKD---QTQ
ILLLVKKFDIGAQRLTGLGHILLSQY---------SKLSQLGTILSKLLN-----ISEEI
TFVEEYGPDGVETV----------------------------------------------
--DNHTELVRTELMD----------GDIITFAINPAEESLTYPF----------------
---------------------YSSIIEYYDYLRNRVKLKFTKTMSYDEEYVL--------
------------------------------------------------------------
-------PDNDGPNEFEFWISVKCTNEELARVVSKYV--NVSPEYLRLYAIYSNGKFS--
------MESGSLLTDYLVKR-----YNRNSIPP--FGYEVLTIPL-----------KEL-
---------EHLRSIKFY---------W-----------LEDSYVHFQSYEFRVANSSTV
SEFLDKVQA---------RIGFDDEKKKQVLLWTNSDFRFQGILSLDSKIE---SIDDSF
LIFARVLPEE-------VSVV-YHLEQLPSAEATDKSSENDLSISKHSNA------EET-
-IVIVQQYFKDWENKHGISFLFTLLPG--E------TFPETKKRLHERFGLG-QKEFS--
-------KIKL-GILYNTEEGPIFK---SLSSDDEEVGEIVLHDLMNNLDFITMDHPDRS
RNQTH---QDRPMMIKN----------------------------
>gi|149411364|ref|XP_001510790.	Ornithorhynchus anatinus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------IVVYLRVKYNFTMFGDLFDEDMYFGSNDNGMN----
-----------GNKTKSKPKDVDPPAH---------------------------------
------------REFTNLSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSLED
KDKPGAKVRIIPLQLQRLFAQLLLLDQQAASTTDLTDSFGWDSSEE----MRQHDVQELN
RILFSALETSLVGTSGHDLINRLYHGTVVNQIV--CKECKNLSEKQEDFLDLTVAVKDV-
-----SGLEDALWNMYVEEEFFDCENLYHCGACDKLVKAVKSTKLRKLPPFLTISLLRFN
FDFVKCERYKETSNYTFPLQLNLKPF----------------------------------
------------CEQNELDDS---------------------------------------
--------------------EYTYDLFSVIIHKGGCYGGHYHVYIKDVDQL--------G
NWQYQEEVAHENTLNSPVDQKEPKTCQEI---------DNPLIVLEAIILQG----CRLI
--QVDQLGQKILKKTGTS----WNKKYRKQHGPIRKFLQSHSQIFLLSSDCSKVGLK---
-------KTHPSQQPKLDFEAHNLN-SSQSSKGLQFPEAQAVGPLELEDGPC--------
-GTH-WFDINDSSVQPIREKDIKKQFEGKESA------------YMLFYRKSQLQ-RPPE
ARSNPRYRVPCHLLNEMD-----------TANIELQQKRADCDSAFNNIDLHLHLGSHYH
FSNGALHPSSSRKESVLDLTIDRRKTLGDLRQSIFQI-LEFWEGDMVLSIAKSV---PAG
LHLFQTL-YGDELSLRGIEIADGEDIFVWNGMEVSGEKIPTGEDCVPVLLTVFRPS----
---ENNGGGKVEQVTESQHVFPANADISSVCTALAFPAGSIWMNGAGSNVTELENWNVIL
KEDMKKTIRECGLKD----------GSSILLLRSNDCQE------RYLRNSFQIPWLQVK
NL-----------CNLECEKDPIKIPVTWEMLMLDIRIKAITELQLPEDLAGNSCLRP--
-------------INRKGKLLPPVPDDFTIKDANLKLGNALGLCPGKAPTSTQLFLYFAL
G------SDLQSGTEMEIIVEETISVKDCLKVMLEKS--GLPGDTWHLRKMDWCYEAGE-
----ALSEENATLKDLELCTGDTLVLTEGKLPP--MGFLKVLLWWY---------QPFTH
SPQENVREQENVTSLGLITSSVKWGLRWRTHVGQGLCAKEAAEVSLRYIGDLEISQEASL
EDLKIQALTLPS------FLEVSIPSPLFLRAWKMERKHPGKLLRNNQQPLKEYKLGERV
EVCVELLQKK-------ENL---GSRDLLLRVQMSIPHEREYSSPVDLAW------DIS-
KECTASSLTQQVANCYSLPVEKIEIAK---------YFPEKFEWMQIN---NWTQQVSKK
KRKKKLENLQT-APYHL-KDGDIIGVKNLLLDDDRDFSTTR--DDMGKKKLQQLT-LGKR
KSRQAARLQNSDIFFDVREEPV---RPHKPEAALSINVGVFR---
>gi|115811670|ref|XP_782883.2|	Strongylocentrotus purpuratus
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------MFGDLFGEEGETSSDVASQ-----
-----------NSAQRSSKKDGLPQPP------------------------------LL-
------------RGSTGLAGIANQGATCYLNSLLQTLLFTPEFRESLFALGQDELGNIAD
KEKPGSKVRVIPIHLQRLFARLLLLNQRSATTEELTDSFGWTNREVH---LQQHDVQELS
RILFCAIEDSLVGTSGENLISRLYRGSIVNQIT--CEECNRISERPEDFVDLTLAVGGY-
-----IGVVDTLRAYYVEEERMEGSNQYRCDRCKKLVNARKGAKLRSLPPILTISLLRFS
YDFVKLERFKETGHYTFPLELDMAPY----------------------------------
------------CEQAKEEAL---------------------------------------
-----------------------YELYSVVLHSGSTHGGHYHAYIRDVDNL--------G
TWSEPHKELIQLTPDSGSGKDDIIDM------------KSPQQCLTALLR-KHGGSEHVL
--SVENLCQVLNQETGVS----WNKRFKRQYGTMTKFLRKYNDLFELNTAGSFVHLVDPM
KGKASSPDQSPSKSPREGARQDNTN-AASEENHVNEEGGEAGQDQSNKERAIARATAKIP
EPGQCWYDFNDSSVEPIRENALYRQFQGRESA------------YMLLYRRKTMT-RPTE
AYNNAYHQMPAWLMAELE-----------TANQELEKQREVYDRSINSVELSLLLSSHCT
WSRGALQLAPDREPVK--ITLDRRKTITHLMGLIKEK--VPEDNNECLHVAKSL---PAG
FHLFDSLTDSPDKTLQDCYVTDQSFIFLWDGKQVDGNSILVGPTSEPILLILTYNAAPPS
NTSTKPTPPPPSSPTELPHGFPKDTRISELRCMVSDIVGIPKHRL--KLSRVQSVPVVVS
SEDDGRTLTQLDFSD----------GDKLMVESTGKDSPKSPRDFLAAREADNQKNSVKL
TIENRCVD-----PDDNGDWPVKQMDIPKDKTVFDLKQLIINTLGLYGNQRPKEGCRL--
-----------RISDDAMGLLAPLHENKSLTDSGVKIGKTIVIETGLPPTSNELTLNF--
-------SLMSGKKSWDMMVDKSTSMSECLTKMLSIA--GMEGTPYHLRKTNWCGEAAD-
----IITDMEQSLLQLHIQDGELLMLEEGRIPP--RGFLLLPVWLYPSPRRTSGAEEGGG
GVSSWMPHVQFANILNSLSSANSPNHDIQQSL-------ETPSNQHELLGEIEISQNATI
GDLKSQVMTLPA------MSQVVVPTVEFLRLRLLEDGRQGRVLRDNNQSLKFARMNIS-
QIAVQILPEE-------EHLR---QTEFVLTFQKRIPDTRLYGTAEDLVW------DAG-
KSAAPSGLRQAIADRLLIPVERVALAKHFTKKAEWIVIPEDKKVSETGKGRGGGKKKGKG
QTHKAI-NLKH-APYLL-RDGDVFGVVD--LKDDPFRKDDFTTIEDDREKERKEEVEQEK
RR----NRRDRRNAVSLGGGESKEKSKKRQEIGLMIKVDNFR---
>gi|68566204|sp|Q8BY87|UBP47_MO	Mus musculus
-----------------------------------------MVPGEENQLVPKE------
----DVFWRCRQNIFDEMKKKFLQIENAAE---EPRVLCII-------------QDTTNS
KTVSERITLNLPASTPVRKLFEDVANKVGYINGTFDLTRENGVTTADMAPLDHTSDKSL-
-----------------------LDANFEPGKKNFLHLTDKDGEPPQMLLEDS-------
-----------NNVDDSVHDRFIGPLP---------------REGSVASTND-----YV-
-SQNYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-DSEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINELYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SSQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMSFPEELDMSTFIDI-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFST----------DDA----VDEGICLE
SSSG----SEKISKPGLEKNSLMYELFSVMVHSGSAAGGHYYACIKSFSD---------D
QWYSFNDQHVSR-----ITQEDIKKTHGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPTRNAK-FLEVDE----YPEHIKNLVQKERELEEQEKRQREIERNTCKIKLF---
-------CLHPVKQVMMENKLEVHK-DKTLKEAVEMAY-----KMMDLEDVI--------
-P----LDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRKPD
QI--FQSYKPGEVMVKVH-----------VVDLKAETVAAPVT-------VRAYLN----
------------------------QTVTEFKQLISKA-THLPADSMRIVLERCY---NDL
RLL-----SMPSKTLKAEGFFRSNKVFVESSETVDHQAAFTDSHLWKLLDRHANTIRLFV
-LLPEQSPGSYSKRTAYQKAGGDSGNVDDDCERVKGPAGNLKSVD--------AILEEST
EKLKSLSLQQQQQDG--------DNGDSSKSTETSDFENIESPLNERGSSTSVDNRELEQ
HI-----------QTSDPEN-FQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADS
AQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGDMQYMYFKA
DPYTADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFV--GVLSSHFKVFRVYTSNQEF--
----ETVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVCQL---------L-----------VNEQEPCKFLLDAVFAKGMTV
RQSKEELIPQLR------EQCGLDLSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNW
EVFLEVLDGV-------EKMK--SMSQLAILTRRWRPAEMKLDPFQELVL------ESN-
---SVDELREKLSEISGIPLEDIEFAKGRG------TFPCDISVLDIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDRTEEVMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDVAQD----------
>gi|14041989|dbj|BAB55063.1|	Homo sapiens
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------MVPGEENQLVPKEAPLDHTSDKSL-
-----------------------LDANFEPGKKNFLHLTDKDGEQPQILLEDS-------
-----------SAGEDSVHDRFIGPLP---------------REGSVGSTSD-----YV-
-SQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFE-------
-ESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEA----WQQHDVQELC
RVMFDALEQKWKQTEQADLINELYQGKLKDYVR--CLECGYEGWRIDTYLDIPLVIRPYG
SSQAFASVEEALHA-FIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFD
FDYTTMHRIKLNDRMTFPEELDMSTFIDV-------------------------------
--EDEKSPQTESCTDSGAENEGSCHSDQMSNDFSN----------DDG----VDEGICLE
TNSG----TEKISKSGLEKNSLIYELFSVMAHSGSAAGGHYYACIKSFSD---------E
QWYSFDDQHVSR-----ITQEDIKKTHGGS--------SGSRGYYSSAFA-SSTNAYMLI
YRLKDPARNAK-FLEVGE----YPEHIKNLVQKERELEEQEKRQREIERNTCKIKLF---
-------CLHPTKQVMMENKLEVHK-DKTLKEAVEMAY-----KMMDLEEVI--------
-P----LDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMF---DLLLETRKPD
QV--FQSYKPGEVMVKVH-----------VVDLKAESVAAPIT-------VRAYLN----
------------------------QTVTEFKQLISKA-IHLPAETMRIVLERCY---NDL
RLL-----SVSSKTLKAEGFFRSNKVFVESSETLDYQMAFADSHLWKLLDRHANTIRLFV
-LLPEQSPVSYSKRTAYQKAGGDSGNVDDDCERVKGPVGSLKSVE--------AILEEST
EKLKSLSLQQQQDGD---------NGDSSKSTETSDFENIESPLNERDSSASVDNRELEQ
HI-----------QTSDPEN-FQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADN
AQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKA
EPYAADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFV--GVLSSHFKVFRVYASNQEF--
----ESVRLNETLSSFSDDN---------------KITIRLGRAL-----------KKG-
---------EYRVKVYQL---------L-----------VNEQEPCKFLLDAVFAKGMTV
RQSKEELIPQLR------EQCGLELSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNW
EVFLEVLDGV-------EKMK--SMSQLAVLSRRWKPSEMKLDPFQEVVL------ESS-
---SVDELREKLSEISGIPLDDIEFAKGRG------TFPCDISVLDIHQDLDWNPKVS--
-------TLNV-WPLYICDDGAVIFYRDKTEELMELTDEQR--NELMKKESSRL--QKTG
HRVTYSPRKEKALKIYLDGAPN-------KDLTQD----------
>gi|125981357|ref|XP_001354685.	Drosophila pseudoobscura
MEIETEQTIEAMDTQDTQE--------------------LPKFKNLIHPQLHAV------
----GGVTQLPNENGNVPPQQLLADSSSSSFTTMDTMTLDD-----------ENKEDQFR
SETTFSYTVDNVGQLKSQRLSPPVYVRM-LPWKIMVIP----NDRALGFFLQCNGEND--
-----------------------SPTWSCNAIAELRLKCHKAESQPFTRARIKHLFYSKE
NDYGYSNFITWQELQDSEKSYI-----------HNNSITLEVHVIADAPHGV-----LW-
-------DS---KKHTGYVGLKNQGATCYMNSLLQTLYFTNSLRLAVYRIPT--------
-EADD-STKSVGLSLQRVFHELQFGD-RPVGTKKLTKSFGWETLDS----FMQHDVQEFL
RVLLDKLESKMKGTCLEGTIPGLFEGKMSSYIK--CKNVDYNSTRYETFYDIQLNIKDK-
-----KNIYESFQD-YVASETLEGDNKYDAGV-HGLQEASKGVIFTSFPPVLHLHLMRFQ
YDPITDSSIKYNDRFEFYEQINLDQYL---------------------------------
------------AEGEKTSAD---------------------------------------
-----------------------YVLHAVLVHSGDNHGGHYVVFINPKAD---------G
RWFKFDDDVVSSC----RKQEAIELNYGGM--------DDEISFHA-----KCSNAYMLV
YIRQSELDRVLGDIPESE----ISSDLVERLDLEKRIEMARRKERSEANLYVSVHVI---
--------LEEYFESQQKRRLFDLE-KTHQR-----------------------------
-P----FKLKQTQTVDELVEMFVKGFGVSRNR------------MRI----WNMCTAQTQ
KFLYFDFEAEASRSIE-------------QIPTSQKP-------------WVIFLE----
------------------------LASPNTSEPLAPF---------------NP---KSD
VLLFLKYYDAKNKRLNYIGCTQQPQS------------RRLIDLCPEVNRKLGFDLDTEL
TVFDEYGDKKIANL---------------------------------------------N
DPIESVLYLPQDNLQ----------GQILIFEREIIDMKLD-------------------
---------------------LPTVEDYFLDLVYRIEIIFSDKCNPNEP-----------
------------------------------------------------------------
--------------DFVLELSNRYNYDQLTNAVAERL--NTDPQKLQFFMCINSYKET--
--------AGNAVPYTFKGTVKDLVSYTKQSTPKRIYYQRLSLSI-----------HEL-
---------DNKKQFKCI---------W-----------VSNDLKEEKELVLYPNKNDNV
KGLLEEAAK---------KITFLENSRKKLRLMKVSNHKIVAHCKDDTPLDTLLKANDSS
ITTTQSAQKI---------------------------YRIEEVPADEMQL------VENE
YLLPVAHFSKELYNSFGVPFFTKARHG--E------SYGALKQRIQKRLNVP-DKEWE--
-------NYKF----TVINTGLTTEVNDNDVINLENFRTSN----SGQLPFLGLDHINKS
RKRSSLNFSEKAIKIYN----------------------------
